Rattus norvegicus

83 known processes

Clu

clusterin

(Aliases: DAG,CLI,SGP2,Trpmb,SP-40,APOJ,SGP-2,TRPM2B,RATTRPM2B,TRPM-2,SP40,Trpm2)

Clu biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to lipidGO:00713962010.433
response to estrogenGO:00436272320.355
response to woundingGO:00096112540.344
carboxylic acid metabolic processGO:00197522890.342
cellular response to oxygen containing compoundGO:19017013860.321
response to inorganic substanceGO:00100353770.319
response to glucocorticoidGO:00513842230.302
regulation of cell proliferationGO:00421273590.302
cellular response to organic cyclic compoundGO:00714072020.245
organic acid metabolic processGO:00060822920.236
response to bacteriumGO:00096172000.234
response to molecule of bacterial originGO:00022371940.233
response to cytokineGO:00340972150.213
cellular response to hormone stimulusGO:00328702470.190
cell projection morphogenesisGO:00488581230.187
reproductive structure developmentGO:00486081280.181
response to peptide hormoneGO:00434342780.172
response to acid chemicalGO:00011012220.169
response to peptideGO:19016522920.163
cellular response to stressGO:00335542690.160
response to external biotic stimulusGO:00432072210.159
response to other organismGO:00517072200.159
oxoacid metabolic processGO:00434362900.153
tissue developmentGO:00098882520.147
programmed cell deathGO:00125013920.145
negative regulation of multicellular organismal processGO:00512412030.144
neuron developmentGO:00486662860.142
immune system processGO:00023762040.141
positive regulation of multicellular organismal processGO:00512403870.135
apoptotic processGO:00069153810.133
single organism reproductive processGO:00447022970.132
cellular response to cytokine stimulusGO:00713451270.131
regulation of nervous system developmentGO:00519602640.126
response to reactive oxygen speciesGO:00003021200.122
agingGO:00075682410.120
response to metal ionGO:00100382530.119
anatomical structure morphogenesisGO:00096532980.118
growthGO:00400071650.117
cellular response to endogenous stimulusGO:00714953770.116
cellular response to nitrogen compoundGO:19016992100.116
neuron differentiationGO:00301823680.115
response to interleukin 1GO:0070555550.111
response to oxidative stressGO:00069791860.107
response to biotic stimulusGO:00096072260.107
regulation of multicellular organismal developmentGO:20000263760.107
regulation of phosphorylationGO:00423252480.106
cellular amino acid metabolic processGO:00065201070.106
defense responseGO:00069521940.105
response to organophosphorusGO:00466831020.104
cellular lipid metabolic processGO:00442552080.103
response to corticosteroidGO:00319602350.102
cell morphogenesis involved in neuron differentiationGO:00486671060.101
neuron apoptotic processGO:0051402880.101
response to extracellular stimulusGO:00099913800.099
response to estradiolGO:00323551640.099
positive regulation of cell proliferationGO:00082842490.096
homeostatic processGO:00425923310.095
positive regulation of nitrogen compound metabolic processGO:00511733340.093
response to carbohydrateGO:00097431830.091
response to nutrient levelsGO:00316673700.090
reproductive processGO:00224143720.090
central nervous system developmentGO:00074173110.089
negative regulation of apoptotic processGO:00430661810.089
gland developmentGO:00487321550.085
neuron projection morphogenesisGO:00488121220.085
regulation of cell developmentGO:00602842630.084
protein phosphorylationGO:00064683450.083
regulation of response to external stimulusGO:00321011060.082
response to decreased oxygen levelsGO:00362932370.082
regulation of phosphate metabolic processGO:00192203490.082
single organism biosynthetic processGO:00447113420.081
cellular response to organonitrogen compoundGO:00714171970.081
catabolic processGO:00090563510.081
regulation of cellular component organizationGO:00511283680.081
epithelium developmentGO:0060429960.080
cell type specific apoptotic processGO:00972851340.080
cell projection organizationGO:00300303020.080
glial cell differentiationGO:0010001650.080
regulation of molecular functionGO:00650093980.079
regulation of neurogenesisGO:00507672470.079
single organism catabolic processGO:00447122830.079
amine metabolic processGO:0009308380.078
regulation of neuron differentiationGO:00456642080.075
response to insulinGO:00328681330.075
negative regulation of response to stimulusGO:00485851550.075
brain developmentGO:00074202470.074
response to lipopolysaccharideGO:00324961910.074
cellular response to reactive oxygen speciesGO:0034614550.074
response to oxygen levelsGO:00704822650.074
reproductive system developmentGO:00614581280.074
cellular response to peptideGO:19016531330.073
gliogenesisGO:0042063930.072
neuron projection developmentGO:00311752730.072
cellular response to interleukin 1GO:0071347370.072
regulation of cell differentiationGO:00455953200.071
immune responseGO:00069551040.071
response to alkaloidGO:00432791320.071
gonad developmentGO:00084061040.070
regulation of apoptotic processGO:00429813350.070
cell part morphogenesisGO:00329901230.070
organic substance catabolic processGO:19015753160.069
cellular response to peptide hormone stimulusGO:00713751200.069
response to hydrogen peroxideGO:0042542890.069
response to toxic substanceGO:00096361330.069
regulation of response to stressGO:00801341260.069
inflammatory responseGO:00069541500.068
cellular catabolic processGO:00442482950.068
sensory organ developmentGO:0007423740.068
response to purine containing compoundGO:00140741260.068
positive regulation of phosphorylationGO:00423271770.067
monocarboxylic acid metabolic processGO:00327871520.067
cellular component movementGO:00069282480.067
development of primary sexual characteristicsGO:00451371070.066
response to campGO:0051591910.064
cell motilityGO:00488702020.064
developmental process involved in reproductionGO:00030061590.063
positive regulation of biosynthetic processGO:00098913190.062
multi organism reproductive processGO:00447032620.062
regenerationGO:00310991630.062
wound healingGO:00420601220.062
positive regulation of neurogenesisGO:00507691650.062
regulation of catalytic activityGO:00507903040.061
head developmentGO:00603222470.061
negative regulation of cell deathGO:00605482290.060
cellular response to oxidative stressGO:0034599760.060
positive regulation of nucleobase containing compound metabolic processGO:00459353190.060
tube developmentGO:0035295890.059
positive regulation of phosphorus metabolic processGO:00105622620.059
localization of cellGO:00516742020.059
regulation of response to woundingGO:1903034690.058
organ morphogenesisGO:0009887750.058
response to mechanical stimulusGO:00096121340.057
cellular component biogenesisGO:00440853680.056
intracellular signal transductionGO:00355563140.056
negative regulation of metabolic processGO:00098923310.056
cellular component assemblyGO:00226073600.056
regulation of cellular amine metabolic processGO:003323880.056
rhythmic processGO:00485111560.054
tissue remodelingGO:0048771400.054
cell morphogenesis involved in differentiationGO:00009041190.054
response to hypoxiaGO:00016662310.054
neurological system processGO:00508772190.054
regulation of cellular amino acid metabolic processGO:000652120.054
regulation of phosphorus metabolic processGO:00511743490.053
negative regulation of cellular metabolic processGO:00313242810.053
macromolecular complex subunit organizationGO:00439333390.052
reproductionGO:00000032450.052
cell morphogenesisGO:00009021420.052
negative regulation of programmed cell deathGO:00430691830.051
positive regulation of developmental processGO:00510942830.051
organophosphate biosynthetic processGO:00904071430.051
cellular component morphogenesisGO:00329891550.051
cellular response to growth factor stimulusGO:00713631620.050
regulation of cellular ketone metabolic processGO:0010565270.050
positive regulation of protein metabolic processGO:00512471780.050
positive regulation of cell developmentGO:00107201760.048
neuronal action potentialGO:0019228350.047
organophosphate metabolic processGO:00196373700.047
cellular amine metabolic processGO:0044106380.047
regulation of neuron projection developmentGO:00109751610.047
multicellular organism reproductionGO:00325042330.046
regulation of system processGO:00440572080.046
single organism behaviorGO:00447081300.046
positive regulation of cellular amine metabolic processGO:003324030.046
multi multicellular organism processGO:00447061380.046
macromolecule catabolic processGO:0009057580.045
regulation of neuron apoptotic processGO:0043523830.044
response to ethanolGO:00454711620.043
positive regulation of nervous system developmentGO:00519621780.043
response to ketoneGO:19016541820.043
lipid metabolic processGO:00066292830.042
regulation of cellular component movementGO:00512701500.042
cellular amide metabolic processGO:0043603440.042
regulation of programmed cell deathGO:00430673410.042
multicellular organismal reproductive processGO:00486092330.042
nitrogen compound transportGO:00717052290.042
fatty acid derivative metabolic processGO:1901568380.041
positive regulation of cellular biosynthetic processGO:00313282950.040
positive regulation of cellular amino acid metabolic processGO:004576410.040
regulation of cellular localizationGO:00603412630.040
cellular response to external stimulusGO:00714961180.040
regulation of protein metabolic processGO:00512462890.040
positive regulation of response to stimulusGO:00485842850.039
neuron deathGO:00709971270.039
regulation of protein phosphorylationGO:00019321830.038
response to growth factorGO:00708481890.038
response to nutrientGO:00075842480.038
positive regulation of transportGO:00510502450.038
axon developmentGO:0061564960.038
negative regulation of response to external stimulusGO:0032102370.037
response to transition metal nanoparticleGO:19902671220.037
cellular ketone metabolic processGO:0042180510.037
cellular homeostasisGO:00197252520.036
regulation of protein modification processGO:00313991940.036
cellular modified amino acid metabolic processGO:0006575610.036
proteolysisGO:00065081750.036
positive regulation of cell differentiationGO:00455972170.036
skeletal system developmentGO:0001501410.036
regulation of locomotionGO:00400121480.036
carbohydrate derivative metabolic processGO:19011353460.035
secretion by cellGO:00329402480.035
regulation of anatomical structure morphogenesisGO:00226031410.035
regulation of secretion by cellGO:19035302080.035
positive regulation of phosphate metabolic processGO:00459372620.034
response to monosaccharideGO:00342841590.034
regulation of cell growthGO:0001558850.034
macromolecular complex assemblyGO:00650032730.034
response to nicotineGO:0035094510.034
fatty acid metabolic processGO:0006631990.034
locomotionGO:00400112370.034
regulation of cell morphogenesis involved in differentiationGO:0010769720.033
regulation of growthGO:00400081050.033
multicellular organismal signalingGO:0035637440.032
lipid biosynthetic processGO:00086101280.032
negative regulation of molecular functionGO:00440921330.032
negative regulation of developmental processGO:00510931250.032
signal transduction by phosphorylationGO:00230141440.032
positive regulation of mapk cascadeGO:0043410920.032
positive regulation of cellular component organizationGO:00511302000.031
regulation of cellular protein metabolic processGO:00322682670.031
positive regulation of cell communicationGO:00106472710.031
regulation of neuron deathGO:19012141150.031
regulation of membrane potentialGO:00423911100.031
positive regulation of gene expressionGO:00106282440.031
secretionGO:00469033070.030
chemical homeostasisGO:00488782920.030
peptide metabolic processGO:0006518320.030
sex differentiationGO:00075481130.030
response to retinoic acidGO:0032526630.029
positive regulation of neuron differentiationGO:00456661260.029
unsaturated fatty acid metabolic processGO:0033559390.029
regulation of axonogenesisGO:0050770370.029
response to vitaminGO:00332731310.029
positive regulation of immune system processGO:0002684900.028
cell growthGO:00160491040.028
negative regulation of signal transductionGO:0009968830.028
negative regulation of neuron apoptotic processGO:0043524450.028
positive regulation of cellular protein metabolic processGO:00322701670.027
positive regulation of molecular functionGO:00440932300.027
negative regulation of gene expressionGO:00106291990.027
female pregnancyGO:00075651220.027
gamete generationGO:00072761240.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
response to amino acidGO:0043200750.026
cellular response to lipopolysaccharideGO:0071222550.026
lipid localizationGO:0010876620.025
negative regulation of response to woundingGO:1903035230.025
cellular response to alcoholGO:0097306870.025
monovalent inorganic cation transportGO:00156721720.025
cell activationGO:0001775970.025
oxidation reduction processGO:00551143040.025
response to axon injuryGO:0048678590.025
regulation of dna metabolic processGO:0051052600.025
regulation of ion transportGO:00432692450.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.025
regulation of cell projection organizationGO:00313441750.025
positive regulation of signalingGO:00230562700.025
regulation of transferase activityGO:00513381230.024
lipid transportGO:0006869610.024
regulation of kinase activityGO:00435491170.024
response to glucoseGO:00097491360.024
protein complex assemblyGO:00064612630.024
cellular chemical homeostasisGO:00550822470.024
organelle organizationGO:00069962660.024
muscle contractionGO:0006936880.024
regulation of immune responseGO:0050776550.024
cellular response to insulin stimulusGO:0032869810.024
positive regulation of rna metabolic processGO:00512542030.024
cellular response to abiotic stimulusGO:0071214850.024
positive regulation of neuron projection developmentGO:0010976990.023
glial cell developmentGO:0021782190.023
single organism carbohydrate metabolic processGO:00447231180.023
dna metabolic processGO:0006259960.023
regulation of secretionGO:00510462240.023
liver developmentGO:0001889900.023
positive regulation of cell projection organizationGO:00313461110.023
cellular response to corticosteroid stimulusGO:0071384690.023
negative regulation of cell proliferationGO:00082851190.023
positive regulation of immune responseGO:0050778420.023
regulation of defense responseGO:0031347680.023
metal ion homeostasisGO:00550651860.023
regulation of immune system processGO:00026821230.022
protein complex biogenesisGO:00702712630.022
cellular response to mechanical stimulusGO:0071260480.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
glutathione metabolic processGO:0006749150.022
salivary gland developmentGO:000743130.022
glycosyl compound metabolic processGO:19016571820.021
male sex differentiationGO:0046661640.021
response to hexoseGO:00097461440.021
cation transportGO:00068123820.021
protein homooligomerizationGO:0051260910.021
multicellular organismal homeostasisGO:0048871490.020
cation homeostasisGO:00550801950.020
response to temperature stimulusGO:0009266940.020
cell cycle checkpointGO:000007520.020
appendage morphogenesisGO:003510740.020
transmission of nerve impulseGO:0019226420.020
circadian rhythmGO:0007623880.020
developmental growthGO:00485891000.020
sensory perceptionGO:00076001010.020
circulatory system processGO:00030131830.020
cellular response to molecule of bacterial originGO:0071219560.019
positive regulation of protein phosphorylationGO:00019341350.019
glycerolipid metabolic processGO:0046486670.019
positive regulation of rna biosynthetic processGO:19026801970.019
regulation of mapk cascadeGO:00434081160.019
regulation of cell morphogenesisGO:0022604770.019
protein complex subunit organizationGO:00718223020.019
sexual reproductionGO:00199531480.019
cardiovascular system developmentGO:00723581340.019
positive regulation of lipid kinase activityGO:009021820.019
single organism cellular localizationGO:19025801020.019
phospholipid biosynthetic processGO:0008654290.018
striated muscle contractionGO:0006941440.018
action potentialGO:0001508540.018
ion homeostasisGO:00508012120.018
mapk cascadeGO:00001651400.018
peptidyl tyrosine phosphorylationGO:0018108720.018
small molecule biosynthetic processGO:00442831240.018
regulation of homeostatic processGO:00328441010.018
organonitrogen compound biosynthetic processGO:19015661670.018
phospholipid metabolic processGO:0006644610.018
axonogenesisGO:0007409710.018
negative regulation of cell communicationGO:00106481580.018
metal ion transportGO:00300012890.018
organ regenerationGO:00311001010.018
carbohydrate metabolic processGO:00059751300.018
regulation of body fluid levelsGO:0050878900.018
regulation of catabolic processGO:00098941130.018
nucleotide metabolic processGO:00091172790.018
regulation of hormone levelsGO:00108171870.018
positive regulation of signal transductionGO:00099671750.018
innate immune responseGO:0045087350.018
peptidyl tyrosine modificationGO:0018212720.017
response to chromateGO:004668730.017
positive regulation of cell deathGO:00109421840.017
response to heatGO:0009408600.017
negative regulation of cellular component organizationGO:0051129830.017
organic hydroxy compound metabolic processGO:19016151150.017
neuron projection regenerationGO:0031102350.017
positive regulation of protein kinase activityGO:0045860730.017
nucleoside phosphate metabolic processGO:00067532830.017
regulation of cell migrationGO:00303341280.017
protein localizationGO:00081041910.017
gastrulationGO:000736920.017
rna biosynthetic processGO:00327743800.017
positive regulation of intracellular signal transductionGO:19025331380.017
behaviorGO:00076102050.017
rna metabolic processGO:00160704060.017
muscle system processGO:00030121150.017
cellular response to steroid hormone stimulusGO:0071383930.017
nucleobase containing small molecule metabolic processGO:00550863160.017
ribose phosphate metabolic processGO:00196932350.017
protein catabolic processGO:0030163300.017
negative regulation of transportGO:00510511360.017
taxisGO:0042330670.017
positive regulation of programmed cell deathGO:00430681570.017
maternal process involved in female pregnancyGO:0060135380.017
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
eye developmentGO:0001654500.016
respiratory system developmentGO:0060541450.016
cellular response to glucocorticoid stimulusGO:0071385680.016
cartilage developmentGO:0051216220.016
regulation of anatomical structure sizeGO:00900661350.016
regulation of wound healingGO:0061041140.016
negative regulation of neurogenesisGO:0050768780.016
regulation of protein kinase activityGO:00458591050.016
negative regulation of cellular protein metabolic processGO:00322691060.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
placenta developmentGO:0001890220.016
response to lead ionGO:0010288330.016
heart morphogenesisGO:000300730.016
immune effector processGO:0002252530.016
regulation of signal transductionGO:00099663180.016
cell migrationGO:00164771970.016
carboxylic acid biosynthetic processGO:0046394830.015
positive regulation of blood circulationGO:1903524650.015
positive regulation of transcription dna templatedGO:00458931970.015
cellular macromolecule catabolic processGO:0044265290.015
circulatory system developmentGO:00723591340.015
camera type eye developmentGO:0043010480.015
purine nucleotide metabolic processGO:00061632290.015
regulation of intracellular signal transductionGO:19025312180.015
positive regulation of kinase activityGO:0033674770.015
carbohydrate derivative catabolic processGO:19011361470.015
single organism carbohydrate catabolic processGO:0044724400.015
protein transportGO:00150311320.015
cellular ion homeostasisGO:00068731840.015
spermatogenesisGO:0007283990.014
regulation of transcription dna templatedGO:00063553740.014
macromolecule localizationGO:00330362520.014
regulation of muscle system processGO:0090257790.014
chemosensory behaviorGO:000763520.014
anion transportGO:00068201780.014
intracellular transportGO:00469071850.014
blood circulationGO:00080151830.014
macroautophagyGO:001623640.014
g protein coupled receptor signaling pathwayGO:00071862420.014
actin cytoskeleton organizationGO:0030036730.014
embryonic skeletal system morphogenesisGO:004870430.014
negative regulation of catalytic activityGO:00430861030.014
regulation of muscle contractionGO:0006937530.014
ras protein signal transductionGO:0007265290.014
male gamete generationGO:0048232990.014
cytoskeleton organizationGO:00070101110.014
positive regulation of catalytic activityGO:00430851840.014
muscle structure developmentGO:0061061870.014
cellular response to metal ionGO:0071248550.014
oligodendrocyte differentiationGO:0048709320.014
heart developmentGO:0007507720.014
male gonad developmentGO:0008584590.014
positive regulation of secretion by cellGO:19035321280.014
cytoplasmic transportGO:00164821150.014
tissue regenerationGO:0042246360.014
peptidyl amino acid modificationGO:00181931260.014
cellular response to inorganic substanceGO:0071241650.013
myelinationGO:0042552390.013
alpha amino acid metabolic processGO:1901605710.013
cellular response to biotic stimulusGO:0071216590.013
protein processingGO:0016485680.013
protein targetingGO:0006605610.013
cellular cation homeostasisGO:00300031800.013
acute inflammatory responseGO:0002526580.013
dna integrity checkpointGO:003157020.013
phenol containing compound metabolic processGO:0018958300.013
axis specificationGO:000979840.013
mitotic spindle organizationGO:000705220.013
positive regulation of protein modification processGO:00314011420.013
odontogenesisGO:0042476320.013
cellular calcium ion homeostasisGO:00068741600.013
eye morphogenesisGO:004859240.013
embryo implantationGO:0007566150.013
inorganic ion transmembrane transportGO:00986602290.013
negative regulation of signalingGO:00230571570.013
multicellular organismal catabolic processGO:004424320.013
divalent inorganic cation homeostasisGO:00725071650.012
cellular metal ion homeostasisGO:00068751720.012
cation transmembrane transportGO:00986552630.012
carboxylic acid transportGO:00469421150.012
dna replicationGO:0006260370.012
stress activated mapk cascadeGO:0051403350.012
negative regulation of neuron deathGO:1901215690.012
negative regulation of protein metabolic processGO:00512481140.012
forebrain developmentGO:0030900980.012
response to starvationGO:0042594590.012
response to tumor necrosis factorGO:0034612560.012
signal releaseGO:00230611450.012
ensheathment of neuronsGO:0007272400.012
hormone metabolic processGO:0042445690.012
response to cadmium ionGO:0046686350.012
brain renin angiotensin systemGO:000203530.012
telencephalon developmentGO:0021537620.012
purine nucleoside metabolic processGO:00422781690.012
aromatic compound catabolic processGO:00194391680.012
regulation of cell motilityGO:20001451310.012
organic acid biosynthetic processGO:0016053830.012
nuclear transportGO:0051169490.012
ribonucleotide metabolic processGO:00092592310.012
transcription dna templatedGO:00063513770.012
defense response to gram negative bacteriumGO:005082930.012
sulfur compound metabolic processGO:0006790700.012
negative regulation of mitotic cell cycle phase transitionGO:190199130.012
ion transmembrane transportGO:00342203650.012
single organism intracellular transportGO:19025821660.012
regulation of hydrolase activityGO:00513361430.012
reactive oxygen species metabolic processGO:0072593370.012
establishment of protein localizationGO:00451841410.012
negative regulation of macromolecule metabolic processGO:00106052600.011
activation of immune responseGO:0002253260.011
synaptic transmissionGO:00072682350.011
transmembrane transportGO:00550854120.011
regulation of rna biosynthetic processGO:20011413810.011
response to gonadotropinGO:0034698340.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.011
inorganic cation transmembrane transportGO:00986622020.011
inner ear receptor cell differentiationGO:006011320.011
protein maturationGO:0051604680.011
purine nucleotide catabolic processGO:00061951360.011
hemopoiesisGO:0030097340.011
hepaticobiliary system developmentGO:0061008900.011
anterior posterior pattern specificationGO:000995210.011
amide transportGO:00428861050.011
regulation of protein maturationGO:1903317500.011

Clu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
nervous system diseaseDOID:86300.066
disease of metabolismDOID:001466700.032
inherited metabolic disorderDOID:65500.032
retinal diseaseDOID:567900.025
retinal degenerationDOID:846600.025
sensory system diseaseDOID:005015500.025
eye diseaseDOID:561400.025
eye and adnexa diseaseDOID:149200.025
gastrointestinal system diseaseDOID:7700.022
hematopoietic system diseaseDOID:7400.016
immune system diseaseDOID:291400.016
primary immunodeficiency diseaseDOID:61200.016
central nervous system diseaseDOID:33100.013