Rattus norvegicus

91 known processes

Lrp6

low density lipoprotein receptor-related protein 6

Lrp6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transcription dna templatedGO:00063513770.152
organic acid metabolic processGO:00060822920.119
cell projection organizationGO:00300303020.090
positive regulation of nucleobase containing compound metabolic processGO:00459353190.089
Human
reproductive processGO:00224143720.073
multi organism reproductive processGO:00447032620.070
multicellular organism reproductionGO:00325042330.067
positive regulation of nitrogen compound metabolic processGO:00511733340.066
Human
positive regulation of signalingGO:00230562700.065
Human
regulation of rna biosynthetic processGO:20011413810.064
positive regulation of cellular biosynthetic processGO:00313282950.062
Human
central nervous system developmentGO:00074173110.062
positive regulation of rna biosynthetic processGO:19026801970.062
Human
gland developmentGO:00487321550.060
cell cell signalingGO:00072673350.060
single organism reproductive processGO:00447022970.060
cellular component biogenesisGO:00440853680.058
regulation of transcription dna templatedGO:00063553740.053
carboxylic acid metabolic processGO:00197522890.052
brain developmentGO:00074202470.050
motor neuron axon guidanceGO:000804510.049
sexual reproductionGO:00199531480.048
response to nutrient levelsGO:00316673700.048
taxisGO:0042330670.048
neuron differentiationGO:00301823680.048
neuron deathGO:00709971270.047
heart morphogenesisGO:000300730.046
negative regulation of multicellular organismal processGO:00512412030.046
cellular response to hormone stimulusGO:00328702470.046
homeostatic processGO:00425923310.045
monocarboxylic acid metabolic processGO:00327871520.044
positive regulation of transcription dna templatedGO:00458931970.044
Human
regulation of cell proliferationGO:00421273590.043
protein phosphorylationGO:00064683450.042
Human
regulation of cellular amino acid metabolic processGO:000652120.042
cellular component assemblyGO:00226073600.042
regulation of neuron differentiationGO:00456642080.042
regulation of protein phosphorylationGO:00019321830.042
Human
multicellular organismal reproductive processGO:00486092330.041
oxoacid metabolic processGO:00434362900.041
response to peptideGO:19016522920.041
negative regulation of osteoblast differentiationGO:004566820.040
regulation of phosphate metabolic processGO:00192203490.040
Human
positive regulation of biosynthetic processGO:00098913190.040
Human
regulation of rna metabolic processGO:00512523910.039
regulation of nucleic acid templated transcriptionGO:19035063800.038
hepaticobiliary system developmentGO:0061008900.038
cellular amino acid metabolic processGO:00065201070.038
cellular response to organonitrogen compoundGO:00714171970.038
reproductionGO:00000032450.037
negative regulation of macromolecule metabolic processGO:00106052600.036
Human
regulation of cellular ketone metabolic processGO:0010565270.036
ribose phosphate metabolic processGO:00196932350.035
regulation of cell developmentGO:00602842630.035
purine nucleoside metabolic processGO:00422781690.034
response to extracellular stimulusGO:00099913800.034
locomotionGO:00400112370.034
blood circulationGO:00080151830.034
response to inorganic substanceGO:00100353770.034
positive regulation of signal transductionGO:00099671750.034
Human
cellular response to oxygen containing compoundGO:19017013860.033
Human
regulation of signal transductionGO:00099663180.033
Human
cellular ketone metabolic processGO:0042180510.032
response to estrogenGO:00436272320.032
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.032
positive regulation of macromolecule biosynthetic processGO:00105572470.032
Human
negative regulation of cellular component organizationGO:0051129830.031
regulation of molecular functionGO:00650093980.031
Human
negative regulation of nervous system developmentGO:0051961790.031
positive regulation of cell communicationGO:00106472710.030
Human
synaptic transmissionGO:00072682350.030
regulation of phosphorus metabolic processGO:00511743490.030
Human
response to purine containing compoundGO:00140741260.030
negative regulation of apoptotic processGO:00430661810.030
Human
cell type specific apoptotic processGO:00972851340.029
Human
nucleotide metabolic processGO:00091172790.029
response to organophosphorusGO:00466831020.029
neuromuscular synaptic transmissionGO:000727420.029
neuron projection developmentGO:00311752730.029
rna biosynthetic processGO:00327743800.029
regulation of multicellular organismal developmentGO:20000263760.029
Human
negative regulation of molecular functionGO:00440921330.028
Human
response to acid chemicalGO:00011012220.028
gamete generationGO:00072761240.028
intracellular transportGO:00469071850.028
purine ribonucleoside metabolic processGO:00461281680.028
negative regulation of gene expressionGO:00106291990.027
mesoderm developmentGO:000749820.027
regulation of neuron deathGO:19012141150.027
positive regulation of molecular functionGO:00440932300.027
Human
response to hexoseGO:00097461440.027
negative regulation of cell proliferationGO:00082851190.026
organic substance catabolic processGO:19015753160.026
regulation of cellular protein metabolic processGO:00322682670.026
Human
amine metabolic processGO:0009308380.026
regulation of catalytic activityGO:00507903040.026
Human
cytoplasmic transportGO:00164821150.025
organelle organizationGO:00069962660.025
cation transportGO:00068123820.025
purine ribonucleotide metabolic processGO:00091502270.025
negative regulation of developmental processGO:00510931250.025
cell motilityGO:00488702020.025
response to nutrientGO:00075842480.025
multi multicellular organism processGO:00447061380.025
positive regulation of response to stimulusGO:00485842850.025
Human
positive regulation of transportGO:00510502450.024
cellular response to endogenous stimulusGO:00714953770.024
regulation of phosphorylationGO:00423252480.024
Human
axonogenesisGO:0007409710.024
positive regulation of gene expressionGO:00106282440.024
Human
nucleic acid templated transcriptionGO:00976593790.024
neuron apoptotic processGO:0051402880.024
negative regulation of nucleic acid templated transcriptionGO:19035071170.024
negative regulation of metabolic processGO:00098923310.024
Human
axis specificationGO:000979840.023
Human
anterior posterior pattern specificationGO:000995210.023
protein complex subunit organizationGO:00718223020.023
multicellular organismal signalingGO:0035637440.023
carbohydrate derivative metabolic processGO:19011353460.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
Human
cellular response to nitrogen compoundGO:19016992100.022
positive regulation of cellular catabolic processGO:0031331710.022
organ formationGO:004864530.022
lipid biosynthetic processGO:00086101280.022
regulation of cellular amine metabolic processGO:003323880.022
regulation of cell motilityGO:20001451310.022
protein complex biogenesisGO:00702712630.022
negative regulation of cellular biosynthetic processGO:00313271610.022
head developmentGO:00603222470.021
regulation of cell differentiationGO:00455953200.021
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
Human
cell morphogenesis involved in neuron differentiationGO:00486671060.021
liver developmentGO:0001889900.021
carbohydrate metabolic processGO:00059751300.021
response to vitaminGO:00332731310.021
positive regulation of intracellular signal transductionGO:19025331380.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
positive regulation of cell proliferationGO:00082842490.020
reproductive system developmentGO:00614581280.020
negative regulation of biosynthetic processGO:00098901680.020
cellular response to lipidGO:00713962010.020
Human
cellular response to stressGO:00335542690.020
establishment of tissue polarityGO:000716420.020
protein complex assemblyGO:00064612630.020
gastrulationGO:000736920.020
ribonucleotide metabolic processGO:00092592310.020
anatomical structure morphogenesisGO:00096532980.020
Human
cell migrationGO:00164771970.020
single organism biosynthetic processGO:00447113420.019
macromolecular complex subunit organizationGO:00439333390.019
cell morphogenesisGO:00009021420.019
Human
muscle system processGO:00030121150.019
nucleoside monophosphate metabolic processGO:0009123930.019
developmental process involved in reproductionGO:00030061590.019
cellular component movementGO:00069282480.019
negative regulation of neuron deathGO:1901215690.019
positive regulation of catabolic processGO:0009896780.019
purine nucleoside triphosphate metabolic processGO:00091441410.019
regulation of programmed cell deathGO:00430673410.019
Human
regulation of canonical wnt signaling pathwayGO:006082840.019
Human
negative regulation of cellular metabolic processGO:00313242810.019
Human
regulation of transcription from rna polymerase ii promoterGO:00063572340.019
Human
nucleoside phosphate metabolic processGO:00067532830.019
regulation of protein modification processGO:00313991940.019
Human
positive regulation of phosphate metabolic processGO:00459372620.018
negative regulation of signalingGO:00230571570.018
negative regulation of protein metabolic processGO:00512481140.018
Human
negative regulation of cell communicationGO:00106481580.018
regulation of mapk cascadeGO:00434081160.018
regulation of membrane potentialGO:00423911100.018
tube developmentGO:0035295890.018
formation of primary germ layerGO:000170410.018
cellular response to acid chemicalGO:0071229750.018
rhythmic processGO:00485111560.018
regulation of cellular carbohydrate metabolic processGO:0010675390.018
response to monosaccharideGO:00342841590.018
cellular response to organic cyclic compoundGO:00714072020.018
Human
negative regulation of macromolecule biosynthetic processGO:00105581480.018
rna metabolic processGO:00160704060.018
female pregnancyGO:00075651220.017
regulation of body fluid levelsGO:0050878900.017
intracellular signal transductionGO:00355563140.017
glucose metabolic processGO:0006006520.017
single organism carbohydrate metabolic processGO:00447231180.017
protein heterooligomerizationGO:0051291890.017
cation transmembrane transportGO:00986552630.017
cardiovascular system developmentGO:00723581340.017
maintenance of locationGO:0051235170.017
ribonucleoside monophosphate metabolic processGO:0009161880.017
response to campGO:0051591910.017
cellular carbohydrate metabolic processGO:0044262720.017
neuron developmentGO:00486662860.017
cell projection morphogenesisGO:00488581230.016
negative regulation of cell developmentGO:0010721820.016
protein oligomerizationGO:00512591910.016
small gtpase mediated signal transductionGO:0007264360.016
regulation of anatomical structure sizeGO:00900661350.016
organophosphate metabolic processGO:00196373700.016
chemical homeostasisGO:00488782920.016
reproductive structure developmentGO:00486081280.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
apoptotic processGO:00069153810.016
Human
single organism catabolic processGO:00447122830.016
cellular amine metabolic processGO:0044106380.016
regulation of apoptotic processGO:00429813350.016
Human
cellular chemical homeostasisGO:00550822470.016
catabolic processGO:00090563510.016
response to decreased oxygen levelsGO:00362932370.016
nucleocytoplasmic transportGO:0006913480.016
positive regulation of cell developmentGO:00107201760.015
regulation of cellular component movementGO:00512701500.015
circulatory system processGO:00030131830.015
programmed cell deathGO:00125013920.015
Human
regulation of blood vessel sizeGO:0050880890.015
regulation of carbohydrate metabolic processGO:0006109410.015
positive regulation of cellular amine metabolic processGO:003324030.015
cellular catabolic processGO:00442482950.015
regulation of locomotionGO:00400121480.015
epithelium developmentGO:0060429960.015
dendrite developmentGO:0016358720.015
glycosyl compound metabolic processGO:19016571820.015
positive regulation of phosphorylationGO:00423271770.015
negative regulation of cell differentiationGO:0045596990.015
lipid storageGO:001991510.015
transmission of nerve impulseGO:0019226420.015
monosaccharide metabolic processGO:0005996610.015
positive regulation of protein phosphorylationGO:00019341350.015
coenzyme metabolic processGO:0006732860.015
response to ethanolGO:00454711620.014
lipid metabolic processGO:00066292830.014
positive regulation of transferase activityGO:0051347810.014
response to growth factorGO:00708481890.014
cytosolic calcium ion homeostasisGO:00514801400.014
ion transmembrane transportGO:00342203650.014
positive regulation of cellular protein metabolic processGO:00322701670.014
regulation of neuron apoptotic processGO:0043523830.014
macromolecular complex assemblyGO:00650032730.014
response to hypoxiaGO:00016662310.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
mesenchymal cell proliferationGO:001046340.014
biological adhesionGO:00226101100.014
circadian rhythmGO:0007623880.014
cell cycleGO:00070491010.014
Human
neuron projection guidanceGO:0097485240.014
inorganic cation transmembrane transportGO:00986622020.014
cellular response to growth factor stimulusGO:00713631620.014
secretionGO:00469033070.014
mammary gland developmentGO:0030879380.014
positive regulation of rna metabolic processGO:00512542030.014
Human
response to mechanical stimulusGO:00096121340.013
regulation of catabolic processGO:00098941130.013
regulation of neuron projection developmentGO:00109751610.013
intracellular protein transportGO:0006886790.013
reactive oxygen species biosynthetic processGO:190340980.013
neuron neuron synaptic transmissionGO:0007270600.013
spermatogenesisGO:0007283990.013
response to insulinGO:00328681330.013
response to corticosteroidGO:00319602350.013
cellular ion homeostasisGO:00068731840.013
development of primary sexual characteristicsGO:00451371070.013
neuron projection morphogenesisGO:00488121220.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
negative regulation of neurogenesisGO:0050768780.013
response to glucoseGO:00097491360.013
localization of cellGO:00516742020.013
nitrogen compound transportGO:00717052290.013
eye morphogenesisGO:004859240.013
positive regulation of protein metabolic processGO:00512471780.013
ras protein signal transductionGO:0007265290.013
peptidyl tyrosine phosphorylationGO:0018108720.013
vascular process in circulatory systemGO:0003018960.013
inflammatory responseGO:00069541500.013
action potentialGO:0001508540.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
behaviorGO:00076102050.013
response to oxygen levelsGO:00704822650.013
regenerationGO:00310991630.013
mesoderm formationGO:000170710.012
agingGO:00075682410.012
autonomic nervous system developmentGO:004848330.012
protein homooligomerizationGO:0051260910.012
organonitrogen compound catabolic processGO:19015651790.012
response to carbohydrateGO:00097431830.012
regulation of protein metabolic processGO:00512462890.012
Human
growthGO:00400071650.012
developmental inductionGO:003112820.012
cell adhesionGO:00071551100.012
regulation of transferase activityGO:00513381230.012
Human
negative regulation of neuron differentiationGO:0045665620.012
regulation of hormone levelsGO:00108171870.012
regulation of nervous system developmentGO:00519602640.012
anion transportGO:00068201780.012
erythrocyte differentiationGO:003021810.012
multicellular organism growthGO:003526410.012
response to alkaloidGO:00432791320.012
chemotaxisGO:0006935660.012
positive regulation of phagocytosis engulfmentGO:006010040.012
vesicle mediated transportGO:00161921810.012
Human
negative regulation of response to stimulusGO:00485851550.012
positive regulation of developmental processGO:00510942830.012
Human
nucleobase containing small molecule metabolic processGO:00550863160.012
heterocycle catabolic processGO:00467001670.012
positive regulation of nervous system developmentGO:00519621780.012
cerebellar granule cell precursor proliferationGO:002193010.012
response to osmotic stressGO:0006970420.012
negative regulation of neuron apoptotic processGO:0043524450.012
hair follicle developmentGO:000194220.012
cellular lipid metabolic processGO:00442552080.012
single organism intracellular transportGO:19025821660.012
regulation of establishment of planar polarityGO:009017520.012
transmembrane transportGO:00550854120.012
purine nucleotide metabolic processGO:00061632290.012
ion homeostasisGO:00508012120.011
positive regulation of neurogenesisGO:00507691650.011
response to estradiolGO:00323551640.011
positive regulation of mesenchymal cell proliferationGO:000205340.011
hexose metabolic processGO:0019318580.011
response to peptide hormoneGO:00434342780.011
regulation of organ formationGO:000315620.011
divalent inorganic cation transportGO:00725111340.011
purine ribonucleotide catabolic processGO:00091541360.011
male gamete generationGO:0048232990.011
sequestering of calcium ionGO:005120880.011
signal transduction by phosphorylationGO:00230141440.011
telencephalon developmentGO:0021537620.011
regulation of cellular component organizationGO:00511283680.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
negative regulation of cellular protein metabolic processGO:00322691060.011
Human
skin morphogenesisGO:004358920.011
rab protein signal transductionGO:003248210.011
purine containing compound metabolic processGO:00725212530.011
nucleoside metabolic processGO:00091161790.011
defense responseGO:00069521940.011
positive regulation of locomotionGO:00400171020.011
regulation of embryonic developmentGO:004599520.011
heart developmentGO:0007507720.011
response to glucocorticoidGO:00513842230.011
neurotransmitter uptakeGO:000150430.011
regulation of anatomical structure morphogenesisGO:00226031410.011
regulation of system processGO:00440572080.011
regulation of secretionGO:00510462240.011
regulation of neurogenesisGO:00507672470.011
regulation of kinase activityGO:00435491170.011
Human
ribonucleoside monophosphate catabolic processGO:0009158550.011
cellular response to abiotic stimulusGO:0071214850.011
regulation of cellular localizationGO:00603412630.011
salivary gland developmentGO:000743130.010
negative regulation of transcription dna templatedGO:00458921160.010
purine ribonucleoside triphosphate metabolic processGO:00092051400.010
synaptic vesicle endocytosisGO:004848840.010
neuronal action potentialGO:0019228350.010
muscle contractionGO:0006936880.010
ribonucleoside metabolic processGO:00091191740.010
heart contractionGO:0060047570.010
purine ribonucleoside monophosphate catabolic processGO:0009169550.010
peptidyl tyrosine modificationGO:0018212720.010
single organism cell adhesionGO:0098602460.010
cell part morphogenesisGO:00329901230.010
negative regulation of nucleobase containing compound metabolic processGO:00459341530.010
mesoderm morphogenesisGO:004833210.010
positive regulation of cell differentiationGO:00455972170.010
molting cycle processGO:002240420.010
cellular component morphogenesisGO:00329891550.010
Human
mechanoreceptor differentiationGO:004249020.010
digestive system developmentGO:0055123410.010

Lrp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.016
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.015
cancerDOID:16200.015
neuropathyDOID:87000.014
neuromuscular diseaseDOID:44000.014
charcot marie tooth diseaseDOID:1059500.014