Rattus norvegicus

0 known processes

Spred1

sprouty-related, EVH1 domain containing 1

Spred1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of phosphate metabolic processGO:00192203490.048
carboxylic acid metabolic processGO:00197522890.047
protein phosphorylationGO:00064683450.045
intracellular signal transductionGO:00355563140.043
oxoacid metabolic processGO:00434362900.040
organic acid metabolic processGO:00060822920.040
regulation of phosphorus metabolic processGO:00511743490.038
cellular ketone metabolic processGO:0042180510.038
regulation of nervous system developmentGO:00519602640.038
regulation of molecular functionGO:00650093980.037
regulation of signal transductionGO:00099663180.036
organophosphate metabolic processGO:00196373700.036
regulation of multicellular organismal developmentGO:20000263760.035
amine metabolic processGO:0009308380.035
regulation of cellular ketone metabolic processGO:0010565270.035
positive regulation of phosphate metabolic processGO:00459372620.035
cellular amino acid metabolic processGO:00065201070.034
regulation of neurogenesisGO:00507672470.034
response to extracellular stimulusGO:00099913800.034
regulation of cellular amino acid metabolic processGO:000652120.034
carbohydrate derivative metabolic processGO:19011353460.034
regulation of nucleic acid templated transcriptionGO:19035063800.034
regulation of cell differentiationGO:00455953200.034
neuron differentiationGO:00301823680.033
regulation of apoptotic processGO:00429813350.033
regulation of programmed cell deathGO:00430673410.033
regulation of cellular protein metabolic processGO:00322682670.033
regulation of protein metabolic processGO:00512462890.032
positive regulation of multicellular organismal processGO:00512403870.032
cellular amine metabolic processGO:0044106380.032
rna biosynthetic processGO:00327743800.031
regulation of transcription dna templatedGO:00063553740.031
regulation of phosphorylationGO:00423252480.031
organic substance catabolic processGO:19015753160.030
regulation of protein modification processGO:00313991940.030
lipid metabolic processGO:00066292830.030
regulation of cell developmentGO:00602842630.029
cellular response to endogenous stimulusGO:00714953770.029
programmed cell deathGO:00125013920.029
transcription dna templatedGO:00063513770.029
regulation of cellular amine metabolic processGO:003323880.029
positive regulation of nitrogen compound metabolic processGO:00511733340.029
regulation of rna biosynthetic processGO:20011413810.029
nucleic acid templated transcriptionGO:00976593790.029
response to oxygen levelsGO:00704822650.029
cellular catabolic processGO:00442482950.029
cellular component biogenesisGO:00440853680.029
positive regulation of developmental processGO:00510942830.029
regulation of intracellular signal transductionGO:19025312180.028
cellular component assemblyGO:00226073600.028
regulation of cellular component organizationGO:00511283680.028
cell projection organizationGO:00300303020.028
positive regulation of phosphorus metabolic processGO:00105622620.028
regulation of catalytic activityGO:00507903040.028
reproductive processGO:00224143720.028
catabolic processGO:00090563510.028
regulation of rna metabolic processGO:00512523910.028
rna metabolic processGO:00160704060.028
cellular response to oxygen containing compoundGO:19017013860.028
single organism biosynthetic processGO:00447113420.027
negative regulation of metabolic processGO:00098923310.027
nucleoside phosphate metabolic processGO:00067532830.027
regulation of neuron differentiationGO:00456642080.026
apoptotic processGO:00069153810.026
protein complex assemblyGO:00064612630.026
single organism reproductive processGO:00447022970.026
organelle organizationGO:00069962660.026
chemical homeostasisGO:00488782920.025
response to decreased oxygen levelsGO:00362932370.025
neuron developmentGO:00486662860.025
single organism catabolic processGO:00447122830.025
nucleobase containing small molecule metabolic processGO:00550863160.025
regulation of cell proliferationGO:00421273590.025
positive regulation of cellular component organizationGO:00511302000.025
positive regulation of response to stimulusGO:00485842850.025
neuron projection developmentGO:00311752730.025
macromolecule localizationGO:00330362520.025
cellular response to stressGO:00335542690.025
purine nucleotide metabolic processGO:00061632290.025
response to hypoxiaGO:00016662310.025
response to peptide hormoneGO:00434342780.024
response to nutrient levelsGO:00316673700.024
central nervous system developmentGO:00074173110.024
regulation of protein phosphorylationGO:00019321830.024
response to peptideGO:19016522920.024
response to nutrientGO:00075842480.024
positive regulation of molecular functionGO:00440932300.023
positive regulation of nucleobase containing compound metabolic processGO:00459353190.023
purine containing compound metabolic processGO:00725212530.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
homeostatic processGO:00425923310.023
negative regulation of cell deathGO:00605482290.023
macromolecular complex subunit organizationGO:00439333390.023
transcription from rna polymerase ii promoterGO:00063662520.023
response to growth factorGO:00708481890.023
negative regulation of cellular metabolic processGO:00313242810.023
positive regulation of cell developmentGO:00107201760.023
cellular component movementGO:00069282480.023
positive regulation of cell communicationGO:00106472710.023
cation transportGO:00068123820.022
negative regulation of apoptotic processGO:00430661810.022
positive regulation of phosphorylationGO:00423271770.022
positive regulation of nervous system developmentGO:00519621780.022
response to inorganic substanceGO:00100353770.022
positive regulation of signalingGO:00230562700.022
positive regulation of cellular amine metabolic processGO:003324030.022
positive regulation of cell differentiationGO:00455972170.022
positive regulation of biosynthetic processGO:00098913190.022
reproductionGO:00000032450.022
protein localizationGO:00081041910.022
metal ion transportGO:00300012890.022
transmembrane transportGO:00550854120.021
negative regulation of multicellular organismal processGO:00512412030.021
positive regulation of cellular biosynthetic processGO:00313282950.021
negative regulation of macromolecule metabolic processGO:00106052600.021
nucleotide metabolic processGO:00091172790.021
ribose phosphate metabolic processGO:00196932350.021
small gtpase mediated signal transductionGO:0007264360.021
cellular response to growth factor stimulusGO:00713631620.021
multi organism reproductive processGO:00447032620.021
purine ribonucleotide metabolic processGO:00091502270.021
positive regulation of protein metabolic processGO:00512471780.021
head developmentGO:00603222470.021
macromolecular complex assemblyGO:00650032730.021
ras protein signal transductionGO:0007265290.021
secretionGO:00469033070.021
cellular response to hormone stimulusGO:00328702470.020
gland developmentGO:00487321550.020
intracellular transportGO:00469071850.020
regulation of cellular localizationGO:00603412630.020
multicellular organismal reproductive processGO:00486092330.020
positive regulation of cell proliferationGO:00082842490.020
regulation of neuron projection developmentGO:00109751610.020
regulation of cell projection organizationGO:00313441750.020
negative regulation of programmed cell deathGO:00430691830.020
protein complex biogenesisGO:00702712630.020
response to metal ionGO:00100382530.020
ribonucleotide metabolic processGO:00092592310.019
negative regulation of natural killer cell mediated immunityGO:000271640.019
agingGO:00075682410.019
vesicle mediated transportGO:00161921810.019
cellular homeostasisGO:00197252520.019
protein complex subunit organizationGO:00718223020.019
multicellular organism reproductionGO:00325042330.019
anatomical structure morphogenesisGO:00096532980.019
brain developmentGO:00074202470.019
positive regulation of protein modification processGO:00314011420.019
single organism intracellular transportGO:19025821660.019
purine ribonucleoside metabolic processGO:00461281680.019
negative regulation of transportGO:00510511360.019
cellular lipid metabolic processGO:00442552080.019
anterior posterior pattern specificationGO:000995210.018
response to corticosteroidGO:00319602350.018
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.018
heterocycle catabolic processGO:00467001670.018
ion transmembrane transportGO:00342203650.018
organic cyclic compound catabolic processGO:19013611750.018
glycosyl compound metabolic processGO:19016571820.018
positive regulation of gene expressionGO:00106282440.018
positive regulation of neurogenesisGO:00507691650.018
response to glucocorticoidGO:00513842230.018
secretion by cellGO:00329402480.018
locomotionGO:00400112370.018
cellular chemical homeostasisGO:00550822470.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
regulation of system processGO:00440572080.017
positive regulation of cellular protein metabolic processGO:00322701670.017
regulation of transferase activityGO:00513381230.017
cell cell signalingGO:00072673350.017
establishment of protein localizationGO:00451841410.017
cellular response to nitrogen compoundGO:19016992100.017
response to ketoneGO:19016541820.017
positive regulation of cell deathGO:00109421840.017
cellular response to organic cyclic compoundGO:00714072020.017
positive regulation of transportGO:00510502450.017
regulation of transcription from rna polymerase ii promoterGO:00063572340.017
cardiovascular system developmentGO:00723581340.017
ribonucleoside metabolic processGO:00091191740.017
negative regulation of cell communicationGO:00106481580.017
cellular nitrogen compound catabolic processGO:00442701630.017
negative regulation of developmental processGO:00510931250.017
response to estrogenGO:00436272320.017
negative regulation of gene expressionGO:00106291990.017
nucleoside metabolic processGO:00091161790.017
cation homeostasisGO:00550801950.017
negative regulation of innate immune responseGO:004582440.016
cell type specific apoptotic processGO:00972851340.016
localization of cellGO:00516742020.016
response to acid chemicalGO:00011012220.016
cell migrationGO:00164771970.016
axis specificationGO:000979840.016
response to cytokineGO:00340972150.016
regulation of kinase activityGO:00435491170.016
cellular protein localizationGO:00346131220.016
aromatic compound catabolic processGO:00194391680.016
positive regulation of transcription dna templatedGO:00458931970.016
regulation of protein kinase activityGO:00458591050.016
neurological system processGO:00508772190.016
positive regulation of catalytic activityGO:00430851840.016
positive regulation of rna metabolic processGO:00512542030.016
circulatory system processGO:00030131830.016
proteolysisGO:00065081750.016
response to woundingGO:00096112540.016
regulation of secretion by cellGO:19035302080.016
negative regulation of cellular biosynthetic processGO:00313271610.016
positive regulation of protein phosphorylationGO:00019341350.016
positive regulation of cell projection organizationGO:00313461110.016
peptidyl amino acid modificationGO:00181931260.015
cellular macromolecule localizationGO:00707271220.015
protein oligomerizationGO:00512591910.015
response to hexoseGO:00097461440.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
circulatory system developmentGO:00723591340.015
cell part morphogenesisGO:00329901230.015
synaptic transmissionGO:00072682350.015
heart morphogenesisGO:000300730.015
single organism organelle organizationGO:19025891800.015
developmental process involved in reproductionGO:00030061590.015
nucleobase containing compound catabolic processGO:00346551520.015
regulation of mapk cascadeGO:00434081160.015
mapk cascadeGO:00001651400.015
purine containing compound catabolic processGO:00725231380.015
metal ion homeostasisGO:00550651860.015
growthGO:00400071650.015
membrane organizationGO:0061024940.015
ion homeostasisGO:00508012120.015
carbohydrate derivative biosynthetic processGO:19011371240.015
positive regulation of signal transductionGO:00099671750.015
positive regulation of neuron differentiationGO:00456661260.014
regulation of ion transportGO:00432692450.014
nucleoside triphosphate metabolic processGO:00091411440.014
response to monosaccharideGO:00342841590.014
negative regulation of signalingGO:00230571570.014
organophosphate catabolic processGO:00464341480.014
response to estradiolGO:00323551640.014
negative regulation of biosynthetic processGO:00098901680.014
tissue developmentGO:00098882520.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
purine nucleoside metabolic processGO:00422781690.014
regulation of catabolic processGO:00098941130.014
negative regulation of cellular protein metabolic processGO:00322691060.014
cell cycleGO:00070491010.014
positive regulation of intracellular signal transductionGO:19025331380.014
negative regulation of molecular functionGO:00440921330.014
organonitrogen compound catabolic processGO:19015651790.014
g protein coupled receptor signaling pathwayGO:00071862420.014
response to carbohydrateGO:00097431830.014
response to oxidative stressGO:00069791860.014
cell motilityGO:00488702020.014
sexual reproductionGO:00199531480.014
cell activationGO:0001775970.014
blood circulationGO:00080151830.014
cell projection morphogenesisGO:00488581230.014
response to mechanical stimulusGO:00096121340.014
calcium ion homeostasisGO:00550741620.014
cytoplasmic transportGO:00164821150.014
regulation of hormone levelsGO:00108171870.014
muscle system processGO:00030121150.014
divalent inorganic cation homeostasisGO:00725071650.014
salivary gland developmentGO:000743130.014
cellular cation homeostasisGO:00300031800.014
nucleoside phosphate catabolic processGO:19012921400.014
single organism cellular localizationGO:19025801020.014
embryonic pattern specificationGO:000988010.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
response to vitaminGO:00332731310.014
neuron deathGO:00709971270.013
immune system processGO:00023762040.013
monovalent inorganic cation transportGO:00156721720.013
behaviorGO:00076102050.013
response to bacteriumGO:00096172000.013
positive regulation of rna biosynthetic processGO:19026801970.013
response to external biotic stimulusGO:00432072210.013
nucleoside catabolic processGO:00091641260.013
cellular response to external stimulusGO:00714961180.013
carbohydrate derivative catabolic processGO:19011361470.013
regenerationGO:00310991630.013
lipid biosynthetic processGO:00086101280.013
signal transduction by phosphorylationGO:00230141440.013
positive regulation of neuron projection developmentGO:0010976990.013
nucleotide catabolic processGO:00091661390.013
cellular metal ion homeostasisGO:00068751720.013
negative regulation of protein metabolic processGO:00512481140.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
regulation of response to stressGO:00801341260.013
response to ethanolGO:00454711620.013
axon developmentGO:0061564960.013
response to molecule of bacterial originGO:00022371940.013
regulation of anatomical structure sizeGO:00900661350.013
synaptic growth at neuromuscular junctionGO:005112410.013
organophosphate biosynthetic processGO:00904071430.013
cellular ion homeostasisGO:00068731840.013
positive regulation of apoptotic processGO:00430651540.013
protein transportGO:00150311320.013
regulation of neuron deathGO:19012141150.013
cellular calcium ion homeostasisGO:00068741600.013
regulation of secretionGO:00510462240.013
regulation of nucleotide metabolic processGO:00061401170.013
nitrogen compound transportGO:00717052290.013
ribonucleotide catabolic processGO:00092611360.013
cell morphogenesis involved in differentiationGO:00009041190.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
ribonucleoside catabolic processGO:00424541260.013
regulation of hydrolase activityGO:00513361430.013
signal releaseGO:00230611450.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
cellular component morphogenesisGO:00329891550.013
female pregnancyGO:00075651220.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.013
response to lipopolysaccharideGO:00324961910.013
regulation of organelle organizationGO:0033043800.013
negative regulation of cell differentiationGO:0045596990.013
neuron projection morphogenesisGO:00488121220.013
action potentialGO:0001508540.013
chromosome segregationGO:000705920.013
purine ribonucleoside catabolic processGO:00461301240.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
regulation of purine nucleotide metabolic processGO:19005421150.012
endocytosisGO:0006897840.012
negative regulation of cell developmentGO:0010721820.012
gamete generationGO:00072761240.012
response to biotic stimulusGO:00096072260.012
regulation of membrane potentialGO:00423911100.012
cellular response to lipidGO:00713962010.012
negative regulation of nervous system developmentGO:0051961790.012
cellular response to organonitrogen compoundGO:00714171970.012
purine ribonucleotide catabolic processGO:00091541360.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
eye morphogenesisGO:004859240.012
positive regulation of mapk cascadeGO:0043410920.012
response to glucoseGO:00097491360.012
positive regulation of programmed cell deathGO:00430681570.012
carbohydrate metabolic processGO:00059751300.012
inorganic ion transmembrane transportGO:00986602290.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
regulation of canonical wnt signaling pathwayGO:006082840.012
defense responseGO:00069521940.012
negative regulation of response to stimulusGO:00485851550.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
gastrulationGO:000736920.012
cellular response to cytokine stimulusGO:00713451270.012
nucleoside triphosphate catabolic processGO:00091431230.012
gtp catabolic processGO:0006184710.012
monocarboxylic acid metabolic processGO:00327871520.011
regulation of anatomical structure morphogenesisGO:00226031410.011
negative regulation of phosphorus metabolic processGO:0010563800.011
positive regulation of secretionGO:00510471400.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
inorganic cation transmembrane transportGO:00986622020.011
peptidyl tyrosine phosphorylationGO:0018108720.011
negative regulation of cellular component organizationGO:0051129830.011
multi multicellular organism processGO:00447061380.011
negative regulation of neurogenesisGO:0050768780.011
divalent inorganic cation transportGO:00725111340.011
regulation of cell motilityGO:20001451310.011
lipid storageGO:001991510.011
intracellular protein transportGO:0006886790.011
rho protein signal transductionGO:0007266110.011
nucleoside phosphate biosynthetic processGO:19012931020.011
purine nucleoside catabolic processGO:00061521240.011
neuron apoptotic processGO:0051402880.011
response to toxic substanceGO:00096361330.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
single organism membrane organizationGO:0044802740.011
reactive nitrogen species metabolic processGO:200105710.011
regulation of cell migrationGO:00303341280.011
reactive oxygen species biosynthetic processGO:190340980.011
sex differentiationGO:00075481130.011
cation transmembrane transportGO:00986552630.011
spindle organizationGO:000705120.011
response to other organismGO:00517072200.011
response to radiationGO:00093141370.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
negative regulation of catalytic activityGO:00430861030.011
reactive oxygen species metabolic processGO:0072593370.011
negative regulation of transcription dna templatedGO:00458921160.011
glycosyl compound catabolic processGO:19016581260.011
gonad developmentGO:00084061040.011
response to alkaloidGO:00432791320.011
reproductive structure developmentGO:00486081280.011
t cell tolerance inductionGO:000251730.011
chemosensory behaviorGO:000763520.011
male gamete generationGO:0048232990.011
regulation of protein localizationGO:0032880810.011
spermatogenesisGO:0007283990.011
regulation of neuron apoptotic processGO:0043523830.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
actin filament based processGO:0030029860.011
liver developmentGO:0001889900.011
regulation of growthGO:00400081050.011
immune responseGO:00069551040.011
response to insulinGO:00328681330.011
positive regulation of transferase activityGO:0051347810.011
development of primary sexual characteristicsGO:00451371070.011
developmental growthGO:00485891000.010
organonitrogen compound biosynthetic processGO:19015661670.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
nucleotide biosynthetic processGO:0009165980.010
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
axonogenesisGO:0007409710.010
regulation of cell cycleGO:0051726730.010
calcium ion transportGO:00068161310.010
regulation of synaptic transmissionGO:00508041410.010
negative regulation of phosphate metabolic processGO:0045936800.010
mesoderm developmentGO:000749820.010
ribonucleotide biosynthetic processGO:0009260850.010
dephosphorylationGO:0016311980.010
cellular response to peptideGO:19016531330.010
mitotic spindle organizationGO:000705220.010
regulation of blood circulationGO:19035221100.010
cytosolic calcium ion homeostasisGO:00514801400.010
positive regulation of cellular component movementGO:00512721020.010
positive regulation of nucleotide metabolic processGO:0045981910.010
negative regulation of rna biosynthetic processGO:19026791180.010
negative regulation of cell cycle phase transitionGO:190198840.010
cell morphogenesisGO:00009021420.010
purine nucleotide catabolic processGO:00061951360.010

Spred1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
musculoskeletal system diseaseDOID:1700.016
disease of metabolismDOID:001466700.013
central nervous system diseaseDOID:33100.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
sensory system diseaseDOID:005015500.011
organ system cancerDOID:005068600.010
connective tissue diseaseDOID:6500.010