Rattus norvegicus

0 known processes

Prok2

prokineticin 2

(Aliases: Bv8)

Prok2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to external biotic stimulusGO:00432072210.504
response to glucocorticoidGO:00513842230.376
response to bacteriumGO:00096172000.333
response to lipopolysaccharideGO:00324961910.321
programmed cell deathGO:00125013920.272
response to other organismGO:00517072200.260
mapk cascadeGO:00001651400.257
response to corticosteroidGO:00319602350.235
cation transportGO:00068123820.222
positive regulation of cell communicationGO:00106472710.221
response to biotic stimulusGO:00096072260.205
response to oxygen levelsGO:00704822650.202
regulation of phosphorylationGO:00423252480.184
signal transduction by phosphorylationGO:00230141440.183
agingGO:00075682410.175
response to cytokineGO:00340972150.175
response to mechanical stimulusGO:00096121340.173
response to campGO:0051591910.156
regulation of apoptotic processGO:00429813350.155
regulation of programmed cell deathGO:00430673410.154
response to inorganic substanceGO:00100353770.153
vasculature developmentGO:0001944700.153
intracellular signal transductionGO:00355563140.153
metal ion transportGO:00300012890.139
regulation of cell proliferationGO:00421273590.133
immune system processGO:00023762040.130
reproductive processGO:00224143720.129
cytosolic calcium ion homeostasisGO:00514801400.120
positive regulation of cell differentiationGO:00455972170.118
tissue developmentGO:00098882520.117
response to nutrient levelsGO:00316673700.115
homeostatic processGO:00425923310.111
apoptotic processGO:00069153810.110
cellular homeostasisGO:00197252520.107
ion transmembrane transportGO:00342203650.107
regulation of anatomical structure morphogenesisGO:00226031410.107
positive regulation of cell proliferationGO:00082842490.106
chemical homeostasisGO:00488782920.103
cell cell signalingGO:00072673350.102
cell migrationGO:00164771970.101
response to hypoxiaGO:00016662310.101
response to organophosphorusGO:00466831020.099
regulation of multicellular organismal developmentGO:20000263760.099
regulation of intracellular signal transductionGO:19025312180.099
positive regulation of nervous system developmentGO:00519621780.099
regulation of vasculature developmentGO:1901342440.097
regulation of molecular functionGO:00650093980.097
response to oxidative stressGO:00069791860.095
negative regulation of cell deathGO:00605482290.094
response to nutrientGO:00075842480.093
regulation of ion transportGO:00432692450.090
circulatory system processGO:00030131830.090
calcium ion homeostasisGO:00550741620.090
angiogenesisGO:0001525530.089
regulation of mapk cascadeGO:00434081160.088
ion homeostasisGO:00508012120.087
g protein coupled receptor signaling pathwayGO:00071862420.086
negative regulation of programmed cell deathGO:00430691830.086
positive regulation of cell deathGO:00109421840.086
cellular ion homeostasisGO:00068731840.083
positive regulation of intracellular signal transductionGO:19025331380.081
response to estrogenGO:00436272320.079
developmental process involved in reproductionGO:00030061590.079
response to molecule of bacterial originGO:00022371940.077
defense responseGO:00069521940.077
monovalent inorganic cation transportGO:00156721720.077
regulation of metal ion transportGO:00109591180.076
response to decreased oxygen levelsGO:00362932370.076
positive regulation of developmental processGO:00510942830.075
brain developmentGO:00074202470.074
regulation of cellular protein metabolic processGO:00322682670.071
regulation of neuron deathGO:19012141150.071
secretionGO:00469033070.071
regulation of angiogenesisGO:0045765390.071
cell motilityGO:00488702020.068
heart contractionGO:0060047570.068
regulation of phosphate metabolic processGO:00192203490.067
regulation of cell developmentGO:00602842630.063
positive regulation of phosphorylationGO:00423271770.063
negative regulation of apoptotic processGO:00430661810.062
cellular response to endogenous stimulusGO:00714953770.062
positive regulation of cellular component movementGO:00512721020.060
cellular response to growth factor stimulusGO:00713631620.059
cardiovascular system developmentGO:00723581340.056
cellular metal ion homeostasisGO:00068751720.056
positive regulation of nitrogen compound metabolic processGO:00511733340.056
response to extracellular stimulusGO:00099913800.055
positive regulation of cell motilityGO:2000147970.055
positive regulation of catalytic activityGO:00430851840.054
regulation of endocrine processGO:0044060210.054
regulation of signal transductionGO:00099663180.053
positive regulation of mapk cascadeGO:0043410920.053
blood circulationGO:00080151830.053
single organism reproductive processGO:00447022970.052
positive regulation of signal transductionGO:00099671750.052
regulation of system processGO:00440572080.052
cellular calcium ion homeostasisGO:00068741600.051
locomotionGO:00400112370.051
organophosphate metabolic processGO:00196373700.051
positive regulation of cell migrationGO:0030335960.050
neuron differentiationGO:00301823680.050
blood vessel morphogenesisGO:0048514580.050
cellular response to cytokine stimulusGO:00713451270.050
positive regulation of phosphorus metabolic processGO:00105622620.049
neurological system processGO:00508772190.049
proteolysisGO:00065081750.048
positive regulation of signalingGO:00230562700.048
response to purine containing compoundGO:00140741260.048
negative regulation of cellular metabolic processGO:00313242810.048
head developmentGO:00603222470.047
localization of cellGO:00516742020.046
multi multicellular organism processGO:00447061380.046
sensory perceptionGO:00076001010.046
neuron deathGO:00709971270.046
synaptic transmissionGO:00072682350.045
regulation of catalytic activityGO:00507903040.045
response to peptideGO:19016522920.045
cellular response to lipidGO:00713962010.044
purine nucleotide catabolic processGO:00061951360.043
cation homeostasisGO:00550801950.043
blood vessel developmentGO:0001568690.043
macromolecule localizationGO:00330362520.043
negative regulation of multicellular organismal processGO:00512412030.042
central nervous system developmentGO:00074173110.042
positive regulation of immune system processGO:0002684900.042
positive regulation of programmed cell deathGO:00430681570.042
regulation of cellular component organizationGO:00511283680.041
positive regulation of neurogenesisGO:00507691650.041
multicellular organismal homeostasisGO:0048871490.040
cellular cation homeostasisGO:00300031800.040
response to acid chemicalGO:00011012220.040
cellular divalent inorganic cation homeostasisGO:00725031620.040
positive regulation of apoptotic processGO:00430651540.040
cellular response to organonitrogen compoundGO:00714171970.040
actin filament based processGO:0030029860.039
inorganic cation transmembrane transportGO:00986622020.039
regulation of membrane potentialGO:00423911100.039
cellular chemical homeostasisGO:00550822470.038
cellular response to nitrogen compoundGO:19016992100.038
sexual reproductionGO:00199531480.038
organ regenerationGO:00311001010.038
aromatic compound catabolic processGO:00194391680.037
ossificationGO:0001503700.037
regulation of protein metabolic processGO:00512462890.037
metal ion homeostasisGO:00550651860.037
positive regulation of cellular component organizationGO:00511302000.037
regulation of cell differentiationGO:00455953200.036
taxisGO:0042330670.036
cellular response to metal ionGO:0071248550.036
positive regulation of multicellular organismal processGO:00512403870.036
regulation of cellular amino acid metabolic processGO:000652120.036
regulation of transferase activityGO:00513381230.036
positive regulation of response to stimulusGO:00485842850.036
muscle contractionGO:0006936880.036
response to metal ionGO:00100382530.035
renal system developmentGO:0072001670.035
cellular amino acid metabolic processGO:00065201070.034
purine containing compound catabolic processGO:00725231380.034
catabolic processGO:00090563510.034
response to radiationGO:00093141370.034
peptide secretionGO:0002790860.034
divalent inorganic cation transportGO:00725111340.034
regulation of secretionGO:00510462240.033
regulation of hormone secretionGO:00468831060.033
sodium ion transportGO:0006814820.033
response to ketoneGO:19016541820.033
response to monosaccharideGO:00342841590.033
positive regulation of molecular functionGO:00440932300.033
immune responseGO:00069551040.033
regulation of neuron apoptotic processGO:0043523830.032
development of primary sexual characteristicsGO:00451371070.032
positive regulation of saliva secretionGO:004687830.032
cellular response to abiotic stimulusGO:0071214850.032
signal releaseGO:00230611450.032
regulation of neurogenesisGO:00507672470.032
transmembrane transportGO:00550854120.032
chemotaxisGO:0006935660.032
positive regulation of biosynthetic processGO:00098913190.032
inflammatory responseGO:00069541500.031
response to ethanolGO:00454711620.031
positive regulation of phosphate metabolic processGO:00459372620.031
circulatory system developmentGO:00723591340.031
regulation of hormone levelsGO:00108171870.031
negative regulation of transportGO:00510511360.030
cellular response to oxygen containing compoundGO:19017013860.030
regulation of phosphorus metabolic processGO:00511743490.030
organelle organizationGO:00069962660.030
establishment of protein localizationGO:00451841410.030
nucleotide catabolic processGO:00091661390.030
nucleoside phosphate catabolic processGO:19012921400.030
regulation of organelle organizationGO:0033043800.029
single organism biosynthetic processGO:00447113420.029
heterocycle catabolic processGO:00467001670.029
regulation of protein kinase activityGO:00458591050.029
membrane organizationGO:0061024940.029
response to heatGO:0009408600.029
positive regulation of cell developmentGO:00107201760.029
cellular amine metabolic processGO:0044106380.029
cytokine productionGO:0001816610.028
sex differentiationGO:00075481130.028
purine ribonucleoside catabolic processGO:00461301240.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.028
tissue remodelingGO:0048771400.028
secretion by cellGO:00329402480.028
response to growth factorGO:00708481890.028
regulation of protein modification processGO:00313991940.028
ribonucleotide catabolic processGO:00092611360.028
hormone secretionGO:00468791150.028
detection of stimulusGO:0051606240.028
regulation of transmembrane transportGO:00347621220.028
regulation of blood circulationGO:19035221100.028
reproductionGO:00000032450.028
positive regulation of protein modification processGO:00314011420.028
response to ionizing radiationGO:0010212590.028
muscle system processGO:00030121150.027
heart processGO:0003015570.027
positive regulation of locomotionGO:00400171020.027
cellular nitrogen compound catabolic processGO:00442701630.027
neuron projection developmentGO:00311752730.027
muscle cell proliferationGO:0033002840.027
cellular response to external stimulusGO:00714961180.027
organonitrogen compound catabolic processGO:19015651790.027
leukocyte migrationGO:0050900380.027
purine ribonucleotide catabolic processGO:00091541360.027
multicellular organismal reproductive processGO:00486092330.026
detection of temperature stimulusGO:001604840.026
regulation of rna biosynthetic processGO:20011413810.026
positive regulation of neuron differentiationGO:00456661260.026
amine metabolic processGO:0009308380.026
regulation of calcium ion transportGO:0051924770.026
cell projection organizationGO:00300303020.026
organophosphate catabolic processGO:00464341480.026
negative regulation of signalingGO:00230571570.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
cell chemotaxisGO:0060326310.025
detection of temperature stimulus involved in sensory perception of painGO:005096540.025
carboxylic acid metabolic processGO:00197522890.025
response to hexoseGO:00097461440.025
regulation of smooth muscle cell proliferationGO:0048660750.025
cellular macromolecule localizationGO:00707271220.025
negative regulation of macromolecule metabolic processGO:00106052600.025
positive regulation of protein metabolic processGO:00512471780.024
regulation of peptide transportGO:0090087870.024
protein localizationGO:00081041910.024
cellular response to organic cyclic compoundGO:00714072020.024
multicellular organism reproductionGO:00325042330.024
regulation of cell migrationGO:00303341280.024
neuron developmentGO:00486662860.024
response to estradiolGO:00323551640.024
response to alkaloidGO:00432791320.024
regulation of cellular amine metabolic processGO:003323880.024
protein maturationGO:0051604680.024
regulation of nervous system developmentGO:00519602640.023
regulation of blood pressureGO:0008217830.023
negative regulation of metabolic processGO:00098923310.023
anatomical structure formation involved in morphogenesisGO:0048646830.023
cellular protein localizationGO:00346131220.023
epithelial cell differentiationGO:0030855710.023
intracellular transportGO:00469071850.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
cellular response to lipopolysaccharideGO:0071222550.023
cellular response to molecule of bacterial originGO:0071219560.023
oxoacid metabolic processGO:00434362900.023
regulation of cell motilityGO:20001451310.022
amide transportGO:00428861050.022
urinary tract smooth muscle contractionGO:001484840.022
nucleotide metabolic processGO:00091172790.022
negative regulation of phosphate metabolic processGO:0045936800.022
rna metabolic processGO:00160704060.022
cardiac muscle contractionGO:0060048270.022
positive regulation of nucleobase containing compound metabolic processGO:00459353190.022
response to glucoseGO:00097491360.022
ribonucleoside triphosphate catabolic processGO:00092031220.022
response to transition metal nanoparticleGO:19902671220.022
cognitionGO:0050890920.022
response to dexamethasoneGO:0071548490.021
neuron apoptotic processGO:0051402880.021
cellular response to stressGO:00335542690.021
positive regulation of cellular amine metabolic processGO:003324030.021
response to tumor necrosis factorGO:0034612560.021
ribose phosphate metabolic processGO:00196932350.021
regulation of hydrolase activityGO:00513361430.020
protein phosphorylationGO:00064683450.020
cellular ketone metabolic processGO:0042180510.020
purine nucleoside catabolic processGO:00061521240.020
regulation of secretion by cellGO:19035302080.020
sensory organ developmentGO:0007423740.020
nucleoside catabolic processGO:00091641260.020
nucleoside metabolic processGO:00091161790.020
growthGO:00400071650.020
cellular catabolic processGO:00442482950.020
positive regulation of transportGO:00510502450.020
involuntary skeletal muscle contractionGO:000301120.019
gliogenesisGO:0042063930.019
regulation of cellular component movementGO:00512701500.019
regulation of ion transmembrane transportGO:00347651210.019
cytoskeleton organizationGO:00070101110.019
negative regulation of cellular protein metabolic processGO:00322691060.019
divalent metal ion transportGO:00708381320.019
female pregnancyGO:00075651220.019
single organism membrane organizationGO:0044802740.019
peptide transportGO:0015833970.019
axon developmentGO:0061564960.019
positive regulation of rna biosynthetic processGO:19026801970.019
reproductive system developmentGO:00614581280.019
regulation of anatomical structure sizeGO:00900661350.019
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.019
regulation of cytoskeleton organizationGO:0051493490.018
divalent inorganic cation homeostasisGO:00725071650.018
biological adhesionGO:00226101100.018
positive regulation of long term synaptic potentiationGO:190027340.018
regulation of protein phosphorylationGO:00019321830.018
cellular response to hormone stimulusGO:00328702470.018
lymphocyte chemotaxisGO:004824730.018
ribonucleoside metabolic processGO:00091191740.018
multi organism reproductive processGO:00447032620.018
anatomical structure morphogenesisGO:00096532980.018
cellular response to hypoxiaGO:0071456510.018
carbohydrate metabolic processGO:00059751300.018
erk1 and erk2 cascadeGO:0070371480.018
urinary bladder smooth muscle contractionGO:001483240.018
response to vitaminGO:00332731310.018
organic cyclic compound catabolic processGO:19013611750.018
regulation of cellular catabolic processGO:00313291010.018
epithelium developmentGO:0060429960.018
negative regulation of neuron deathGO:1901215690.018
positive regulation of transferase activityGO:0051347810.017
reactive oxygen species metabolic processGO:0072593370.017
regulation of vasoconstrictionGO:0019229440.017
striated muscle tissue developmentGO:0014706580.017
positive regulation of gene expressionGO:00106282440.017
single organism catabolic processGO:00447122830.017
single organism intracellular transportGO:19025821660.017
response to woundingGO:00096112540.017
negative regulation of cellular biosynthetic processGO:00313271610.017
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
cellular response to oxidative stressGO:0034599760.017
behaviorGO:00076102050.017
vascular process in circulatory systemGO:0003018960.017
synaptic transmission glutamatergicGO:0035249330.017
endoplasmic reticulum organizationGO:000702910.017
regulation of synaptic transmissionGO:00508041410.017
purine containing compound metabolic processGO:00725212530.017
positive regulation of smooth muscle cell proliferationGO:0048661510.017
cellular response to transforming growth factor beta stimulusGO:0071560410.017
meiotic cell cycle processGO:190304630.017
regulation of organ formationGO:000315620.016
organic acid metabolic processGO:00060822920.016
cation transmembrane transportGO:00986552630.016
negative regulation of gene expressionGO:00106291990.016
intracellular protein transportGO:0006886790.016
positive regulation of cytosolic calcium ion concentrationGO:00072041220.016
sodium ion transmembrane transportGO:0035725670.016
sensory perception of painGO:0019233730.016
cell type specific apoptotic processGO:00972851340.016
positive regulation of cellular biosynthetic processGO:00313282950.016
vesicle mediated transportGO:00161921810.016
cytoplasmic transportGO:00164821150.016
cellular response to oxygen levelsGO:0071453600.016
positive regulation of cellular protein metabolic processGO:00322701670.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
negative regulation of cell communicationGO:00106481580.016
endocrine processGO:0050886320.016
regulation of kinase activityGO:00435491170.016
cellular response to tumor necrosis factorGO:0071356460.016
single organism cellular localizationGO:19025801020.016
response to peptide hormoneGO:00434342780.015
negative regulation of developmental processGO:00510931250.015
purine nucleoside triphosphate catabolic processGO:00091461220.015
regulation of cell adhesionGO:0030155520.015
protein transportGO:00150311320.015
regulation of proteolysisGO:0030162660.015
response to temperature stimulusGO:0009266940.015
single organism carbohydrate metabolic processGO:00447231180.015
organ formationGO:004864530.015
organic substance catabolic processGO:19015753160.015
regulation of neuron differentiationGO:00456642080.014
calcium ion transportGO:00068161310.014
peptidyl amino acid modificationGO:00181931260.014
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.014
protein processingGO:0016485680.014
cell cell signaling involved in cell fate commitmentGO:004516820.014
regulation of defense responseGO:0031347680.014
regulation of immune system processGO:00026821230.014
regulation of neuron projection developmentGO:00109751610.014
multicellular organism growthGO:003526410.014
potassium ion transportGO:0006813970.014
regulation of peptide secretionGO:0002791820.014
cellular response to inorganic substanceGO:0071241650.014
positive regulation of protein phosphorylationGO:00019341350.014
regenerationGO:00310991630.014
guanosine containing compound metabolic processGO:1901068740.014
defense response to gram negative bacteriumGO:005082930.014
gtp catabolic processGO:0006184710.014
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.014
regulation of cellular ketone metabolic processGO:0010565270.014
negative regulation of nitrogen compound metabolic processGO:00511721610.014
regulation of ion transmembrane transporter activityGO:0032412480.014
positive regulation of synaptic transmissionGO:0050806620.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
formation of primary germ layerGO:000170410.014
nucleoside triphosphate catabolic processGO:00091431230.014
positive regulation of angiogenesisGO:0045766280.014
regulation of chronic inflammatory responseGO:000267630.014
hormone transportGO:00099141210.013
negative regulation of protein processingGO:0010955470.013
response to cgmpGO:007030530.013
purine nucleotide metabolic processGO:00061632290.013
small gtpase mediated signal transductionGO:0007264360.013
rhythmic processGO:00485111560.013
negative regulation of ion transportGO:0043271510.013
cellular component assemblyGO:00226073600.013
response to gamma radiationGO:0010332240.013
reproductive structure developmentGO:00486081280.013
cellular response to reactive oxygen speciesGO:0034614550.013
positive regulation of chemotaxisGO:0050921230.013
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.013
regulation of response to stressGO:00801341260.013
response to carbohydrateGO:00097431830.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
regulation of cell projection organizationGO:00313441750.013
regulation of cytokine productionGO:0001817560.013
single organism behaviorGO:00447081300.013
cellular component movementGO:00069282480.013
positive regulation of the force of heart contraction by norepinephrineGO:000306110.013
positive regulation of cell projection organizationGO:00313461110.013
feeding behaviorGO:0007631530.013
nucleobase containing compound catabolic processGO:00346551520.013
positive regulation of kinase activityGO:0033674770.013
single organism organelle organizationGO:19025891800.013
ribonucleoside catabolic processGO:00424541260.012
regulation of locomotionGO:00400121480.012
actin cytoskeleton organizationGO:0030036730.012
inorganic ion transmembrane transportGO:00986602290.012
positive regulation of ion transportGO:0043270940.012
macromolecular complex assemblyGO:00650032730.012
response to lithium ionGO:0010226280.012
carbohydrate derivative catabolic processGO:19011361470.012
ribonucleotide metabolic processGO:00092592310.012
regulation of muscle contractionGO:0006937530.012
mechanoreceptor differentiationGO:004249020.012
eye developmentGO:0001654500.012
nucleobase containing small molecule metabolic processGO:00550863160.012
gamete generationGO:00072761240.012
saliva secretionGO:004654130.012
defense response to other organismGO:0098542170.012
cell adhesionGO:00071551100.012
regulation of muscle system processGO:0090257790.012
regulation of the force of heart contraction by chemical signalGO:000305720.012
dna metabolic processGO:0006259960.012
positive regulation of blood circulationGO:1903524650.012
striated muscle contractionGO:0006941440.012
negative regulation of secretionGO:0051048820.012
female sex differentiationGO:0046660590.012
purine nucleoside metabolic processGO:00422781690.012
regulation of blood vessel sizeGO:0050880890.012
regulation of saliva secretionGO:004687730.012
ras protein signal transductionGO:0007265290.012
negative regulation of molecular functionGO:00440921330.012
regulation of synaptic transmission glutamatergicGO:0051966260.012
response to antibioticGO:0046677390.012
purine ribonucleotide metabolic processGO:00091502270.012
regulation of endopeptidase activityGO:0052548510.012
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.012
gonad developmentGO:00084061040.012
calcium ion importGO:0070509220.011
gland developmentGO:00487321550.011
regulation of purine nucleotide catabolic processGO:0033121650.011
regulation of catabolic processGO:00098941130.011
cell morphogenesis involved in differentiationGO:00009041190.011
hematopoietic progenitor cell differentiationGO:000224420.011
temperature homeostasisGO:0001659170.011
regulation of synaptic plasticityGO:0048167700.011
regulation of erk1 and erk2 cascadeGO:0070372410.011
cellular response to alcoholGO:0097306870.011
regulation of actin filament based processGO:0032970420.011
developmental inductionGO:003112820.011
negative regulation of proteolysisGO:0045861410.011
muscle structure developmentGO:0061061870.011
guanosine containing compound catabolic processGO:1901069710.011
response to transforming growth factor betaGO:0071559460.011
oxidation reduction processGO:00551143040.011
positive regulation of map kinase activityGO:0043406460.011
regulation of nucleoside metabolic processGO:0009118660.011
response to corticosteroneGO:0051412400.011
leukocyte activationGO:0045321760.011
negative regulation of protein metabolic processGO:00512481140.011
negative regulation of cellular component organizationGO:0051129830.011
regulation of gtp catabolic processGO:0033124580.011

Prok2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
nervous system diseaseDOID:86300.035
disease of cellular proliferationDOID:1456600.016
sensory system diseaseDOID:005015500.013
retinal diseaseDOID:567900.013
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013
retinal degenerationDOID:846600.011