Rattus norvegicus

14 known processes

Adam15

a disintegrin and metallopeptidase domain 15 (metargidin)

(Aliases: tMDCVI,MDC15)

Adam15 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
catabolic processGO:00090563510.095
apoptotic processGO:00069153810.092
Rat
nucleobase containing small molecule metabolic processGO:00550863160.088
cellular ketone metabolic processGO:0042180510.078
positive regulation of nucleobase containing compound metabolic processGO:00459353190.075
single organism catabolic processGO:00447122830.069
organic substance catabolic processGO:19015753160.067
response to metal ionGO:00100382530.067
regulation of apoptotic processGO:00429813350.060
Rat
female pregnancyGO:00075651220.058
reproductive processGO:00224143720.057
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.057
carbohydrate derivative metabolic processGO:19011353460.056
intracellular signal transductionGO:00355563140.056
Human
regulation of cell motilityGO:20001451310.055
Human
organophosphate metabolic processGO:00196373700.054
programmed cell deathGO:00125013920.054
Rat
response to peptideGO:19016522920.051
purine nucleotide metabolic processGO:00061632290.050
tissue developmentGO:00098882520.050
regulation of phosphate metabolic processGO:00192203490.049
nucleoside metabolic processGO:00091161790.048
nucleoside phosphate metabolic processGO:00067532830.048
organonitrogen compound catabolic processGO:19015651790.048
organic acid metabolic processGO:00060822920.047
purine containing compound metabolic processGO:00725212530.047
ribose phosphate metabolic processGO:00196932350.046
organelle organizationGO:00069962660.045
single organism biosynthetic processGO:00447113420.044
carbohydrate derivative catabolic processGO:19011361470.044
ribonucleotide metabolic processGO:00092592310.042
g protein coupled receptor signaling pathwayGO:00071862420.041
single organism carbohydrate metabolic processGO:00447231180.041
response to extracellular stimulusGO:00099913800.041
protein complex subunit organizationGO:00718223020.041
response to nutrient levelsGO:00316673700.039
regulation of phosphorus metabolic processGO:00511743490.035
cellular amine metabolic processGO:0044106380.034
multi multicellular organism processGO:00447061380.034
cellular amino acid metabolic processGO:00065201070.033
nucleotide metabolic processGO:00091172790.033
single organism reproductive processGO:00447022970.033
Rat
rna metabolic processGO:00160704060.032
regulation of signal transductionGO:00099663180.032
negative regulation of cell deathGO:00605482290.032
Rat
oxoacid metabolic processGO:00434362900.032
multi organism reproductive processGO:00447032620.032
Rat
positive regulation of apoptotic processGO:00430651540.032
aromatic compound catabolic processGO:00194391680.031
positive regulation of biosynthetic processGO:00098913190.031
response to growth factorGO:00708481890.030
regulation of cellular amino acid metabolic processGO:000652120.030
negative regulation of signalingGO:00230571570.030
cellular component assemblyGO:00226073600.029
regulation of multicellular organismal developmentGO:20000263760.029
response to nutrientGO:00075842480.029
organophosphate biosynthetic processGO:00904071430.029
purine ribonucleotide metabolic processGO:00091502270.028
brain developmentGO:00074202470.027
amine metabolic processGO:0009308380.026
positive regulation of cellular biosynthetic processGO:00313282950.026
regulation of protein metabolic processGO:00512462890.025
negative regulation of response to stimulusGO:00485851550.025
positive regulation of cell deathGO:00109421840.025
carbohydrate metabolic processGO:00059751300.025
organic cyclic compound catabolic processGO:19013611750.025
regulation of catalytic activityGO:00507903040.025
regulation of purine nucleotide metabolic processGO:19005421150.024
regulation of cellular amine metabolic processGO:003323880.024
locomotionGO:00400112370.024
Human
ribonucleoside catabolic processGO:00424541260.024
regulation of hydrolase activityGO:00513361430.024
nucleoside phosphate catabolic processGO:19012921400.024
nucleoside triphosphate metabolic processGO:00091411440.024
regulation of cellular ketone metabolic processGO:0010565270.023
agingGO:00075682410.023
negative regulation of gene expressionGO:00106291990.023
cellular nitrogen compound catabolic processGO:00442701630.023
immune system processGO:00023762040.022
Human
negative regulation of transportGO:00510511360.022
regulation of phosphorylationGO:00423252480.022
regulation of nucleic acid templated transcriptionGO:19035063800.022
response to ketoneGO:19016541820.022
vesicle mediated transportGO:00161921810.022
nucleoside phosphate biosynthetic processGO:19012931020.022
cellular catabolic processGO:00442482950.022
metal ion transportGO:00300012890.022
transcription dna templatedGO:00063513770.022
nucleoside catabolic processGO:00091641260.021
purine nucleotide catabolic processGO:00061951360.021
organonitrogen compound biosynthetic processGO:19015661670.021
ribonucleoside triphosphate metabolic processGO:00091991410.021
response to estrogenGO:00436272320.021
atp catabolic processGO:0006200540.021
central nervous system developmentGO:00074173110.021
macromolecular complex assemblyGO:00650032730.020
purine nucleoside triphosphate metabolic processGO:00091441410.020
response to peptide hormoneGO:00434342780.020
response to ethanolGO:00454711620.020
regulation of cellular protein metabolic processGO:00322682670.020
cellular component movementGO:00069282480.020
Human
positive regulation of multicellular organismal processGO:00512403870.020
growthGO:00400071650.019
positive regulation of catalytic activityGO:00430851840.019
purine containing compound catabolic processGO:00725231380.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
purine nucleotide biosynthetic processGO:0006164830.019
negative regulation of cell communicationGO:00106481580.019
cellular component biogenesisGO:00440853680.018
purine ribonucleotide biosynthetic processGO:0009152810.018
response to inorganic substanceGO:00100353770.018
purine ribonucleoside catabolic processGO:00461301240.018
positive regulation of programmed cell deathGO:00430681570.018
regulation of programmed cell deathGO:00430673410.018
Rat
positive regulation of purine nucleotide metabolic processGO:1900544910.018
purine ribonucleoside monophosphate metabolic processGO:0009167840.018
nucleobase containing compound catabolic processGO:00346551520.018
response to decreased oxygen levelsGO:00362932370.018
reproductive system developmentGO:00614581280.017
protein phosphorylationGO:00064683450.017
nucleotide catabolic processGO:00091661390.017
regulation of nucleotide metabolic processGO:00061401170.017
purine ribonucleotide catabolic processGO:00091541360.017
regulation of secretion by cellGO:19035302080.017
secretionGO:00469033070.017
negative regulation of apoptotic processGO:00430661810.017
Rat
negative regulation of metabolic processGO:00098923310.017
regulation of protein phosphorylationGO:00019321830.017
response to cytokineGO:00340972150.017
carboxylic acid metabolic processGO:00197522890.017
response to glucocorticoidGO:00513842230.017
organophosphate catabolic processGO:00464341480.017
icosanoid metabolic processGO:0006690380.017
protein complex biogenesisGO:00702712630.017
small molecule biosynthetic processGO:00442831240.017
lipid metabolic processGO:00066292830.016
macromolecular complex subunit organizationGO:00439333390.016
positive regulation of cellular amine metabolic processGO:003324030.016
regulation of cellular catabolic processGO:00313291010.016
regulation of molecular functionGO:00650093980.016
Human
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
neurological system processGO:00508772190.016
response to radiationGO:00093141370.016
regulation of cellular component movementGO:00512701500.016
Human
regulation of neuron differentiationGO:00456642080.016
positive regulation of developmental processGO:00510942830.016
response to interleukin 1GO:0070555550.016
ribonucleoside metabolic processGO:00091191740.016
wound healingGO:00420601220.016
cellular lipid metabolic processGO:00442552080.016
positive regulation of phosphorus metabolic processGO:00105622620.016
neuron differentiationGO:00301823680.015
positive regulation of gene expressionGO:00106282440.015
negative regulation of protein metabolic processGO:00512481140.015
purine containing compound biosynthetic processGO:0072522850.015
negative regulation of macromolecule metabolic processGO:00106052600.015
ion transmembrane transportGO:00342203650.015
positive regulation of response to stimulusGO:00485842850.015
nucleotide biosynthetic processGO:0009165980.015
regulation of cellular localizationGO:00603412630.015
cellular response to abiotic stimulusGO:0071214850.015
positive regulation of signalingGO:00230562700.015
inorganic ion transmembrane transportGO:00986602290.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
cellular metal ion homeostasisGO:00068751720.015
secretion by cellGO:00329402480.015
purine nucleoside metabolic processGO:00422781690.015
positive regulation of protein metabolic processGO:00512471780.015
carbohydrate derivative biosynthetic processGO:19011371240.014
positive regulation of phosphorylationGO:00423271770.014
ribonucleotide catabolic processGO:00092611360.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
developmental growthGO:00485891000.014
positive regulation of signal transductionGO:00099671750.014
response to temperature stimulusGO:0009266940.014
proteolysisGO:00065081750.014
Human Rat
ras protein signal transductionGO:0007265290.014
enzyme linked receptor protein signaling pathwayGO:00071671160.014
regulation of neurogenesisGO:00507672470.014
cyclic nucleotide metabolic processGO:0009187800.014
ribose phosphate biosynthetic processGO:0046390870.014
head developmentGO:00603222470.014
single organism organelle organizationGO:19025891800.013
ion homeostasisGO:00508012120.013
response to oxygen levelsGO:00704822650.013
glycosyl compound metabolic processGO:19016571820.013
positive regulation of hydrolase activityGO:0051345860.013
positive regulation of nucleotide metabolic processGO:0045981910.013
cytoskeleton organizationGO:00070101110.013
regulation of protein modification processGO:00313991940.013
response to woundingGO:00096112540.013
developmental process involved in reproductionGO:00030061590.013
transmembrane transportGO:00550854120.013
positive regulation of transcription dna templatedGO:00458931970.013
cellular calcium ion homeostasisGO:00068741600.013
negative regulation of signal transductionGO:0009968830.013
homeostatic processGO:00425923310.012
glycosyl compound catabolic processGO:19016581260.012
cellular response to endogenous stimulusGO:00714953770.012
skeletal system developmentGO:0001501410.012
connective tissue developmentGO:0061448330.012
localization of cellGO:00516742020.012
Human
transcription from rna polymerase ii promoterGO:00063662520.012
positive regulation of nucleic acid templated transcriptionGO:19035081970.012
negative regulation of cellular protein metabolic processGO:00322691060.012
positive regulation of rna metabolic processGO:00512542030.012
regulation of cell differentiationGO:00455953200.012
divalent inorganic cation transportGO:00725111340.012
positive regulation of cell proliferationGO:00082842490.012
behaviorGO:00076102050.012
cellular response to stressGO:00335542690.012
small gtpase mediated signal transductionGO:0007264360.012
negative regulation of catalytic activityGO:00430861030.012
ribonucleotide biosynthetic processGO:0009260850.012
cellular chemical homeostasisGO:00550822470.012
cell migrationGO:00164771970.012
Human
heterocycle catabolic processGO:00467001670.012
negative regulation of multicellular organismal processGO:00512412030.012
regenerationGO:00310991630.011
defense responseGO:00069521940.011
Human
regulation of cyclic nucleotide biosynthetic processGO:0030802450.011
positive regulation of cell communicationGO:00106472710.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
regulation of cell migrationGO:00303341280.011
Human
cellular response to oxygen containing compoundGO:19017013860.011
actin filament based processGO:0030029860.011
regulation of intracellular signal transductionGO:19025312180.011
single organism intracellular transportGO:19025821660.011
cellular homeostasisGO:00197252520.011
single organism cellular localizationGO:19025801020.011
potassium ion transportGO:0006813970.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
blood vessel morphogenesisGO:0048514580.011
regulation of homeostatic processGO:00328441010.011
regulation of ion transportGO:00432692450.011
organic acid biosynthetic processGO:0016053830.011
monovalent inorganic cation transportGO:00156721720.011
regulation of hormone levelsGO:00108171870.011
hormone transportGO:00099141210.011
multicellular organism growthGO:003526410.011
epithelial cell differentiationGO:0030855710.011
protein oligomerizationGO:00512591910.011
metal ion homeostasisGO:00550651860.010
positive regulation of nervous system developmentGO:00519621780.010
inorganic cation transmembrane transportGO:00986622020.010
tissue regenerationGO:0042246360.010
chemical homeostasisGO:00488782920.010
response to molecule of bacterial originGO:00022371940.010
cellular cation homeostasisGO:00300031800.010
nucleoside triphosphate catabolic processGO:00091431230.010
response to monosaccharideGO:00342841590.010
peptide hormone secretionGO:0030072840.010
neuron developmentGO:00486662860.010
unsaturated fatty acid metabolic processGO:0033559390.010
cell motilityGO:00488702020.010
Human

Adam15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.058
nervous system diseaseDOID:86300.058
central nervous system diseaseDOID:33100.034
muscle tissue diseaseDOID:6600.016
muscular dystrophyDOID:988400.016
musculoskeletal system diseaseDOID:1700.016
muscular diseaseDOID:008000000.016
myopathyDOID:42300.016
cerebral degenerationDOID:144300.016
brain diseaseDOID:93600.016
disease of metabolismDOID:001466700.012