Rattus norvegicus

27 known processes

Macf1

microtubule-actin crosslinking factor 1

Macf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.171
regulation of phosphate metabolic processGO:00192203490.152
positive regulation of multicellular organismal processGO:00512403870.151
regulation of signal transductionGO:00099663180.134
cellular component movementGO:00069282480.121
single organism catabolic processGO:00447122830.119
neuron projection developmentGO:00311752730.116
regulation of intracellular signal transductionGO:19025312180.113
positive regulation of cellular biosynthetic processGO:00313282950.111
positive regulation of phosphate metabolic processGO:00459372620.109
nucleobase containing small molecule metabolic processGO:00550863160.108
regulation of cellular ketone metabolic processGO:0010565270.107
regulation of phosphorus metabolic processGO:00511743490.102
oxoacid metabolic processGO:00434362900.101
cellular amino acid metabolic processGO:00065201070.093
cellular component assemblyGO:00226073600.091
cellular catabolic processGO:00442482950.090
carboxylic acid metabolic processGO:00197522890.089
cell projection organizationGO:00300303020.088
intracellular signal transductionGO:00355563140.088
neuron deathGO:00709971270.087
locomotionGO:00400112370.084
positive regulation of developmental processGO:00510942830.084
head developmentGO:00603222470.083
catabolic processGO:00090563510.082
positive regulation of cell projection organizationGO:00313461110.082
positive regulation of neurogenesisGO:00507691650.082
programmed cell deathGO:00125013920.081
regulation of protein phosphorylationGO:00019321830.076
regulation of molecular functionGO:00650093980.073
regulation of phosphorylationGO:00423252480.073
anatomical structure morphogenesisGO:00096532980.072
regulation of nervous system developmentGO:00519602640.071
cellular component biogenesisGO:00440853680.068
g protein coupled receptor signaling pathwayGO:00071862420.068
protein localizationGO:00081041910.067
regulation of cellular component organizationGO:00511283680.067
regulation of apoptotic processGO:00429813350.067
neuron differentiationGO:00301823680.062
regulation of protein modification processGO:00313991940.062
macromolecule localizationGO:00330362520.061
cellular response to growth factor stimulusGO:00713631620.061
protein complex subunit organizationGO:00718223020.059
cellular response to endogenous stimulusGO:00714953770.059
regulation of cellular protein metabolic processGO:00322682670.058
protein heterooligomerizationGO:0051291890.058
regulation of locomotionGO:00400121480.058
regulation of transferase activityGO:00513381230.057
cellular response to stressGO:00335542690.057
protein complex assemblyGO:00064612630.057
regulation of multicellular organismal developmentGO:20000263760.057
negative regulation of developmental processGO:00510931250.055
protein phosphorylationGO:00064683450.055
gap junction assemblyGO:001626420.054
protein complex biogenesisGO:00702712630.054
regulation of mapk cascadeGO:00434081160.053
regulation of neurogenesisGO:00507672470.053
macromolecular complex assemblyGO:00650032730.052
response to growth factorGO:00708481890.051
negative regulation of cell differentiationGO:0045596990.051
positive regulation of phosphorus metabolic processGO:00105622620.050
ras protein signal transductionGO:0007265290.050
regulation of cellular amino acid metabolic processGO:000652120.050
positive regulation of cell deathGO:00109421840.049
positive regulation of biosynthetic processGO:00098913190.049
positive regulation of nucleobase containing compound metabolic processGO:00459353190.049
cation homeostasisGO:00550801950.048
cell cell signalingGO:00072673350.048
positive regulation of amine transportGO:0051954260.047
positive regulation of nervous system developmentGO:00519621780.047
regulation of cell projection organizationGO:00313441750.046
regulation of cell differentiationGO:00455953200.046
cell morphogenesis involved in neuron differentiationGO:00486671060.046
macromolecular complex subunit organizationGO:00439333390.045
neuron developmentGO:00486662860.045
mapk cascadeGO:00001651400.044
cellular response to nitrogen compoundGO:19016992100.044
inorganic ion transmembrane transportGO:00986602290.044
positive regulation of nitrogen compound metabolic processGO:00511733340.043
regulation of cellular amine metabolic processGO:003323880.043
positive regulation of cell differentiationGO:00455972170.043
regulation of cellular localizationGO:00603412630.042
response to purine containing compoundGO:00140741260.042
cell morphogenesis involved in differentiationGO:00009041190.041
cellular response to oxygen containing compoundGO:19017013860.040
organophosphate catabolic processGO:00464341480.040
positive regulation of cell migrationGO:0030335960.040
organelle organizationGO:00069962660.040
signal transduction by phosphorylationGO:00230141440.039
amine metabolic processGO:0009308380.039
small gtpase mediated signal transductionGO:0007264360.039
carbohydrate metabolic processGO:00059751300.039
regulation of neuron differentiationGO:00456642080.038
positive regulation of cellular component organizationGO:00511302000.038
cellular ketone metabolic processGO:0042180510.038
apoptotic processGO:00069153810.038
regulation of programmed cell deathGO:00430673410.038
response to oxygen levelsGO:00704822650.037
tissue developmentGO:00098882520.037
Rat
carbohydrate derivative metabolic processGO:19011353460.036
regulation of neuron projection developmentGO:00109751610.036
intracellular transportGO:00469071850.036
negative regulation of cell communicationGO:00106481580.036
cellular response to organonitrogen compoundGO:00714171970.036
regulation of cellular component movementGO:00512701500.036
cellular amine metabolic processGO:0044106380.035
protein oligomerizationGO:00512591910.035
positive regulation of response to stimulusGO:00485842850.035
positive regulation of cell developmentGO:00107201760.035
positive regulation of ras gtpase activityGO:0032320280.034
synaptic transmissionGO:00072682350.033
positive regulation of programmed cell deathGO:00430681570.033
cell migrationGO:00164771970.033
regulation of catalytic activityGO:00507903040.033
positive regulation of gtpase activityGO:0043547470.033
purine ribonucleotide metabolic processGO:00091502270.033
neurological system processGO:00508772190.033
positive regulation of protein metabolic processGO:00512471780.032
cellular ion homeostasisGO:00068731840.032
chemical homeostasisGO:00488782920.032
inorganic cation transmembrane transportGO:00986622020.032
positive regulation of macromolecule biosynthetic processGO:00105572470.032
purine containing compound catabolic processGO:00725231380.031
regulation of cell morphogenesisGO:0022604770.031
response to organophosphorusGO:00466831020.030
positive regulation of neuron projection developmentGO:0010976990.030
positive regulation of phosphorylationGO:00423271770.030
cell cycleGO:00070491010.030
regulation of cell developmentGO:00602842630.029
localization of cellGO:00516742020.029
regulation of neuron deathGO:19012141150.029
cell projection morphogenesisGO:00488581230.029
regulation of cell proliferationGO:00421273590.028
regulation of cell motilityGO:20001451310.028
organic substance catabolic processGO:19015753160.028
multicellular organism growthGO:003526410.027
negative regulation of signalingGO:00230571570.027
cell morphogenesisGO:00009021420.027
negative regulation of cellular component organizationGO:0051129830.027
regulation of anatomical structure morphogenesisGO:00226031410.027
cellular protein localizationGO:00346131220.027
positive regulation of cellular amino acid metabolic processGO:004576410.027
cellular divalent inorganic cation homeostasisGO:00725031620.027
positive regulation of locomotionGO:00400171020.026
reproductive processGO:00224143720.026
Rat
cytosolic calcium ion homeostasisGO:00514801400.026
regulation of synaptic transmissionGO:00508041410.026
enzyme linked receptor protein signaling pathwayGO:00071671160.026
brain developmentGO:00074202470.026
heterocycle catabolic processGO:00467001670.025
negative regulation of signal transductionGO:0009968830.025
regulation of protein metabolic processGO:00512462890.025
nitrogen compound transportGO:00717052290.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.025
axonogenesisGO:0007409710.025
positive regulation of cytosolic calcium ion concentrationGO:00072041220.025
cation transportGO:00068123820.025
regulation of hydrolase activityGO:00513361430.025
carbohydrate derivative catabolic processGO:19011361470.025
lipid metabolic processGO:00066292830.025
single organism intracellular transportGO:19025821660.025
cardiovascular system developmentGO:00723581340.025
positive regulation of molecular functionGO:00440932300.025
central nervous system developmentGO:00074173110.025
regulation of cell migrationGO:00303341280.024
action potentialGO:0001508540.024
positive regulation of intracellular signal transductionGO:19025331380.024
ion transmembrane transportGO:00342203650.024
negative regulation of response to stimulusGO:00485851550.024
calcium ion homeostasisGO:00550741620.024
homeostatic processGO:00425923310.024
positive regulation of purine nucleotide metabolic processGO:1900544910.024
circulatory system developmentGO:00723591340.024
positive regulation of transportGO:00510502450.024
metal ion homeostasisGO:00550651860.024
positive regulation of cellular component movementGO:00512721020.023
organonitrogen compound catabolic processGO:19015651790.023
developmental growthGO:00485891000.023
positive regulation of neuron differentiationGO:00456661260.023
cellular homeostasisGO:00197252520.023
positive regulation of nucleotide metabolic processGO:0045981910.023
response to extracellular stimulusGO:00099913800.023
Rat
cell part morphogenesisGO:00329901230.022
cytoskeleton organizationGO:00070101110.022
positive regulation of cell motilityGO:2000147970.022
secretion by cellGO:00329402480.022
positive regulation of cellular amine metabolic processGO:003324030.022
response to metal ionGO:00100382530.022
ribonucleotide metabolic processGO:00092592310.022
purine ribonucleoside catabolic processGO:00461301240.022
regulation of kinase activityGO:00435491170.022
transmembrane transportGO:00550854120.022
cell type specific apoptotic processGO:00972851340.022
alcohol metabolic processGO:0006066770.021
cellular metal ion homeostasisGO:00068751720.021
reproductionGO:00000032450.021
ion homeostasisGO:00508012120.021
regulation of canonical wnt signaling pathwayGO:006082840.021
rna biosynthetic processGO:00327743800.021
divalent inorganic cation homeostasisGO:00725071650.021
regulation of ras gtpase activityGO:0032318320.021
positive regulation of cell communicationGO:00106472710.021
single organism organelle organizationGO:19025891800.021
response to acid chemicalGO:00011012220.021
cellular component morphogenesisGO:00329891550.021
regulation of ion transportGO:00432692450.021
cellular macromolecule localizationGO:00707271220.020
positive regulation of protein modification processGO:00314011420.020
response to carbohydrateGO:00097431830.020
cell cycle processGO:0022402570.020
response to increased oxygen levelsGO:0036296450.020
ribonucleoside catabolic processGO:00424541260.020
calcium ion transportGO:00068161310.020
regulation of anatomical structure sizeGO:00900661350.019
organic cyclic compound catabolic processGO:19013611750.019
response to decreased oxygen levelsGO:00362932370.019
motor neuron axon guidanceGO:000804510.019
positive regulation of mapk cascadeGO:0043410920.019
protein targetingGO:0006605610.019
cellular lipid metabolic processGO:00442552080.019
glycosyl compound catabolic processGO:19016581260.019
metal ion transportGO:00300012890.019
cellular chemical homeostasisGO:00550822470.018
response to hypoxiaGO:00016662310.018
regulation of protein kinase activityGO:00458591050.018
regulation of cellular component biogenesisGO:0044087860.018
ribose phosphate metabolic processGO:00196932350.018
regulation of small gtpase mediated signal transductionGO:0051056480.018
response to alkaloidGO:00432791320.018
positive regulation of apoptotic processGO:00430651540.018
positive regulation of norepinephrine secretionGO:001070140.018
positive regulation of catalytic activityGO:00430851840.018
eye morphogenesisGO:004859240.018
regulation of gtpase activityGO:0043087570.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
carboxylic acid transportGO:00469421150.018
positive regulation of secretion by cellGO:19035321280.018
cation transmembrane transportGO:00986552630.018
protein tetramerizationGO:0051262380.018
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
protein modification by small protein conjugationGO:0032446310.017
stress activated protein kinase signaling cascadeGO:0031098370.017
metanephric comma shaped body morphogenesisGO:007227820.017
positive regulation of purine nucleotide catabolic processGO:0033123530.017
growthGO:00400071650.017
multi organism reproductive processGO:00447032620.017
Rat
single organism carbohydrate metabolic processGO:00447231180.017
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.017
cytoskeleton dependent cytokinesisGO:006164020.017
sequestering of calcium ionGO:005120880.017
regulation of neuron apoptotic processGO:0043523830.017
cell motilityGO:00488702020.016
nucleoside phosphate metabolic processGO:00067532830.016
nucleoside phosphate catabolic processGO:19012921400.016
neuron projection morphogenesisGO:00488121220.016
positive regulation of transcription dna templatedGO:00458931970.016
amine transportGO:0015837570.016
cellular cation homeostasisGO:00300031800.016
purine nucleoside triphosphate metabolic processGO:00091441410.016
transcription from rna polymerase ii promoterGO:00063662520.016
purine nucleoside catabolic processGO:00061521240.016
vesicle mediated transportGO:00161921810.016
aromatic compound catabolic processGO:00194391680.016
regulation of secretionGO:00510462240.016
protein transportGO:00150311320.016
nucleoside metabolic processGO:00091161790.016
ribonucleoside metabolic processGO:00091191740.016
glycosyl compound metabolic processGO:19016571820.016
secretionGO:00469033070.016
positive regulation of gene expressionGO:00106282440.016
carbohydrate derivative biosynthetic processGO:19011371240.016
regulation of rna biosynthetic processGO:20011413810.016
taxisGO:0042330670.016
regulation of transcription dna templatedGO:00063553740.015
rna metabolic processGO:00160704060.015
positive regulation of signalingGO:00230562700.015
positive regulation of cellular protein metabolic processGO:00322701670.015
cellular calcium ion homeostasisGO:00068741600.015
regulation of cell cycleGO:0051726730.015
axis specificationGO:000979840.015
cellular nitrogen compound catabolic processGO:00442701630.015
divalent inorganic cation transportGO:00725111340.015
anatomical structure formation involved in morphogenesisGO:0048646830.015
regulation of response to stressGO:00801341260.015
ribonucleoside triphosphate metabolic processGO:00091991410.015
calcium ion transmembrane transportGO:0070588700.015
multicellular organismal reproductive processGO:00486092330.015
purine nucleoside triphosphate catabolic processGO:00091461220.015
regulation of purine nucleotide catabolic processGO:0033121650.015
nucleoside triphosphate catabolic processGO:00091431230.014
purine nucleotide metabolic processGO:00061632290.014
gastrulationGO:000736920.014
positive regulation of protein phosphorylationGO:00019341350.014
stress activated mapk cascadeGO:0051403350.014
purine nucleoside metabolic processGO:00422781690.014
gtp catabolic processGO:0006184710.014
organelle localizationGO:0051640550.014
actin filament based processGO:0030029860.014
regulation of metal ion transportGO:00109591180.014
multicellular organism reproductionGO:00325042330.014
regulation of calcium ion transportGO:0051924770.014
response to inorganic substanceGO:00100353770.014
rho protein signal transductionGO:0007266110.014
response to peptideGO:19016522920.014
anion transportGO:00068201780.014
negative regulation of neurogenesisGO:0050768780.014
positive regulation of cell proliferationGO:00082842490.014
regenerationGO:00310991630.014
cellular response to lipidGO:00713962010.014
establishment of protein localizationGO:00451841410.014
cytoplasmic transportGO:00164821150.014
organic hydroxy compound transportGO:0015850770.014
positive regulation of ion transportGO:0043270940.013
heart developmentGO:0007507720.013
actin cytoskeleton organizationGO:0030036730.013
organic anion transportGO:00157111320.013
neuron projection guidanceGO:0097485240.013
maintenance of locationGO:0051235170.013
regulation of stress activated protein kinase signaling cascadeGO:0070302230.013
positive regulation of secretionGO:00510471400.013
potassium ion transportGO:0006813970.013
organophosphate metabolic processGO:00196373700.013
regulation of secretion by cellGO:19035302080.013
monovalent inorganic cation transportGO:00156721720.013
axon developmentGO:0061564960.013
regulation of rna metabolic processGO:00512523910.013
regulation of response to external stimulusGO:00321011060.013
retinal ganglion cell axon guidanceGO:003129010.013
chemotaxisGO:0006935660.013
regulation of system processGO:00440572080.013
dicarboxylic acid transportGO:0006835340.013
chromosome segregationGO:000705920.013
positive regulation of signal transductionGO:00099671750.013
anterior posterior pattern specificationGO:000995210.013
amino acid transportGO:0006865700.013
negative regulation of neuron differentiationGO:0045665620.013
ribonucleoside triphosphate catabolic processGO:00092031220.012
purine nucleotide catabolic processGO:00061951360.012
positive regulation of rna metabolic processGO:00512542030.012
negative regulation of cell projection organizationGO:0031345500.012
positive regulation of cellular component biogenesisGO:0044089550.012
behaviorGO:00076102050.012
sequestering of metal ionGO:005123890.012
regulation of ras protein signal transductionGO:0046578450.012
sexual reproductionGO:00199531480.012
muscle system processGO:00030121150.012
positive regulation of hydrolase activityGO:0051345860.012
muscle cell differentiationGO:0042692520.012
divalent metal ion transportGO:00708381320.012
phospholipid metabolic processGO:0006644610.012
forebrain developmentGO:0030900980.012
response to monosaccharideGO:00342841590.012
cellular response to hormone stimulusGO:00328702470.012
regulation of nucleotide metabolic processGO:00061401170.012
nucleobase containing compound catabolic processGO:00346551520.012
response to woundingGO:00096112540.012
regulation of growthGO:00400081050.012
transmission of nerve impulseGO:0019226420.012
negative regulation of cell deathGO:00605482290.012
negative regulation of gene expressionGO:00106291990.012
regulation of jnk cascadeGO:0046328190.012
response to peptide hormoneGO:00434342780.012
response to hyperoxiaGO:0055093450.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
dna metabolic processGO:0006259960.011
regulation of gtp catabolic processGO:0033124580.011
learning or memoryGO:0007611900.011
positive regulation of nucleoside metabolic processGO:0045979550.011
nucleic acid templated transcriptionGO:00976593790.011
response to estrogenGO:00436272320.011
intracellular protein transportGO:0006886790.011
cellular response to organic cyclic compoundGO:00714072020.011
response to external biotic stimulusGO:00432072210.011
pyrimidine nucleobase catabolic processGO:000620830.011
jnk cascadeGO:0007254280.011
immune responseGO:00069551040.011
sympathetic nervous system developmentGO:004848510.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
ribonucleotide catabolic processGO:00092611360.011
cellular response to cytokine stimulusGO:00713451270.011
single organism cellular localizationGO:19025801020.011
response to oxidative stressGO:00069791860.011
neuron apoptotic processGO:0051402880.011
regulation of purine nucleotide metabolic processGO:19005421150.011
response to insulinGO:00328681330.011
negative regulation of apoptotic processGO:00430661810.011
multicellular organismal signalingGO:0035637440.011
positive regulation of erk1 and erk2 cascadeGO:0070374290.011
cytosolic calcium ion transportGO:0060401390.011
single organism biosynthetic processGO:00447113420.011
blood vessel developmentGO:0001568690.011
response to magnesium ionGO:0032026200.011
response to fatty acidGO:0070542650.011
nucleoside triphosphate metabolic processGO:00091411440.011
axon guidanceGO:0007411240.011
purine containing compound metabolic processGO:00725212530.011
guanosine containing compound catabolic processGO:1901069710.011
regulation of dendrite developmentGO:0050773590.010
positive regulation of catabolic processGO:0009896780.010
catecholamine secretionGO:0050432330.010
defense responseGO:00069521940.010
striated muscle tissue developmentGO:0014706580.010
response to ammonium ionGO:0060359710.010
purine ribonucleoside metabolic processGO:00461281680.010
nucleotide catabolic processGO:00091661390.010
rhythmic processGO:00485111560.010
regulation of protein localizationGO:0032880810.010
peptidyl amino acid modificationGO:00181931260.010
sensory perception of bitter tasteGO:005091340.010
regulation of cellular response to stressGO:0080135490.010
negative regulation of cell developmentGO:0010721820.010
regulation of synaptic plasticityGO:0048167700.010
negative regulation of neuron projection developmentGO:0010977460.010
negative regulation of multicellular organismal processGO:00512412030.010
regulation of hormone levelsGO:00108171870.010
cellular carbohydrate metabolic processGO:0044262720.010
positive regulation of gtp catabolic processGO:0033126480.010
response to calcium ionGO:0051592590.010

Macf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.017
disease of anatomical entityDOID:700.017
urinary system diseaseDOID:1800.016
central nervous system diseaseDOID:33100.013
kidney diseaseDOID:55700.011