Rattus norvegicus

72 known processes

Htt

huntingtin

(Aliases: Hd,Hdh)

Htt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.170
positive regulation of transportGO:00510502450.105
Human
vesicle mediated transportGO:00161921810.084
Human
carboxylic acid metabolic processGO:00197522890.084
positive regulation of signalingGO:00230562700.078
Human
catabolic processGO:00090563510.077
cellular component biogenesisGO:00440853680.073
macromolecule localizationGO:00330362520.072
regulation of rna metabolic processGO:00512523910.072
regulation of molecular functionGO:00650093980.072
cellular amino acid metabolic processGO:00065201070.070
rna metabolic processGO:00160704060.070
cellular component assemblyGO:00226073600.068
regulation of phosphate metabolic processGO:00192203490.068
Human
single organism intracellular transportGO:19025821660.066
Human
homeostatic processGO:00425923310.065
cation transportGO:00068123820.065
Human
protein localizationGO:00081041910.063
organonitrogen compound catabolic processGO:19015651790.062
carbohydrate derivative metabolic processGO:19011353460.061
ion transmembrane transportGO:00342203650.060
Human
organic acid metabolic processGO:00060822920.060
regulation of cellular protein metabolic processGO:00322682670.059
response to nutrient levelsGO:00316673700.058
neuron differentiationGO:00301823680.058
programmed cell deathGO:00125013920.057
Human
cellular catabolic processGO:00442482950.056
regulation of signal transductionGO:00099663180.055
Human
central nervous system developmentGO:00074173110.055
cellular homeostasisGO:00197252520.055
macromolecular complex assemblyGO:00650032730.054
synaptic transmissionGO:00072682350.053
macromolecular complex subunit organizationGO:00439333390.053
response to inorganic substanceGO:00100353770.052
purine containing compound metabolic processGO:00725212530.052
response to acid chemicalGO:00011012220.050
regulation of cellular localizationGO:00603412630.050
intracellular signal transductionGO:00355563140.050
Human
organophosphate metabolic processGO:00196373700.050
cellular response to oxygen containing compoundGO:19017013860.049
regulation of transcription dna templatedGO:00063553740.048
neuron developmentGO:00486662860.048
cellular response to endogenous stimulusGO:00714953770.048
protein phosphorylationGO:00064683450.047
apoptotic processGO:00069153810.047
Human
response to extracellular stimulusGO:00099913800.046
response to nutrientGO:00075842480.046
positive regulation of cell communicationGO:00106472710.044
Human
protein autophosphorylationGO:0046777660.044
regulation of apoptotic processGO:00429813350.044
Human
negative regulation of cellular metabolic processGO:00313242810.044
positive regulation of phosphate metabolic processGO:00459372620.044
anatomical structure morphogenesisGO:00096532980.044
positive regulation of phosphorus metabolic processGO:00105622620.044
regulation of phosphorus metabolic processGO:00511743490.043
Human
protein complex assemblyGO:00064612630.043
cellular response to hormone stimulusGO:00328702470.043
divalent inorganic cation homeostasisGO:00725071650.042
reproductionGO:00000032450.042
regulation of protein modification processGO:00313991940.042
regulation of phosphorylationGO:00423252480.041
cellular amine metabolic processGO:0044106380.041
regulation of locomotionGO:00400121480.041
cell cell signalingGO:00072673350.040
nitrogen compound transportGO:00717052290.040
nucleotide metabolic processGO:00091172790.040
protein complex biogenesisGO:00702712630.040
positive regulation of cellular biosynthetic processGO:00313282950.040
nucleic acid templated transcriptionGO:00976593790.039
single organism biosynthetic processGO:00447113420.039
single organism reproductive processGO:00447022970.038
single organism catabolic processGO:00447122830.038
locomotionGO:00400112370.038
anion transportGO:00068201780.038
purine ribonucleotide metabolic processGO:00091502270.038
protein complex subunit organizationGO:00718223020.038
regulation of system processGO:00440572080.038
amine metabolic processGO:0009308380.038
transcription dna templatedGO:00063513770.038
rna biosynthetic processGO:00327743800.038
transmembrane transportGO:00550854120.037
Human
nucleoside phosphate metabolic processGO:00067532830.036
chemical homeostasisGO:00488782920.036
response to corticosteroidGO:00319602350.036
cell motilityGO:00488702020.036
organic substance catabolic processGO:19015753160.036
alpha amino acid metabolic processGO:1901605710.035
agingGO:00075682410.034
cellular cation homeostasisGO:00300031800.034
intracellular transportGO:00469071850.034
Human
cation homeostasisGO:00550801950.034
organophosphate biosynthetic processGO:00904071430.034
positive regulation of signal transductionGO:00099671750.033
Human
nucleobase containing small molecule metabolic processGO:00550863160.033
multi organism reproductive processGO:00447032620.033
cellular nitrogen compound catabolic processGO:00442701630.033
cellular response to lipidGO:00713962010.033
aromatic compound catabolic processGO:00194391680.033
purine nucleotide metabolic processGO:00061632290.032
cellular chemical homeostasisGO:00550822470.032
reproductive processGO:00224143720.032
regulation of cellular ketone metabolic processGO:0010565270.032
organic anion transportGO:00157111320.032
regulation of cellular amine metabolic processGO:003323880.031
cellular macromolecule localizationGO:00707271220.031
response to estrogenGO:00436272320.031
regulation of cell differentiationGO:00455953200.031
heterocycle catabolic processGO:00467001670.031
negative regulation of cell communicationGO:00106481580.030
Human
regulation of protein metabolic processGO:00512462890.030
endocytosisGO:0006897840.030
carboxylic acid transportGO:00469421150.030
nucleobase containing compound catabolic processGO:00346551520.030
regulation of cellular amino acid metabolic processGO:000652120.030
nucleoside metabolic processGO:00091161790.030
positive regulation of nitrogen compound metabolic processGO:00511733340.029
response to campGO:0051591910.029
response to estradiolGO:00323551640.029
negative regulation of cell deathGO:00605482290.029
Human
mesoderm developmentGO:000749820.029
regulation of cell proliferationGO:00421273590.029
purine nucleoside metabolic processGO:00422781690.028
purine ribonucleoside metabolic processGO:00461281680.028
ribonucleotide catabolic processGO:00092611360.028
behaviorGO:00076102050.028
regulation of rna biosynthetic processGO:20011413810.028
cytoplasmic transportGO:00164821150.028
ion homeostasisGO:00508012120.028
tissue developmentGO:00098882520.028
ribonucleoside metabolic processGO:00091191740.028
negative regulation of multicellular organismal processGO:00512412030.027
head developmentGO:00603222470.027
positive regulation of molecular functionGO:00440932300.027
Human
anion transmembrane transportGO:0098656770.027
positive regulation of catalytic activityGO:00430851840.027
ribose phosphate metabolic processGO:00196932350.027
metal ion homeostasisGO:00550651860.027
positive regulation of response to stimulusGO:00485842850.026
Human
response to metal ionGO:00100382530.026
reactive oxygen species metabolic processGO:0072593370.026
cell projection morphogenesisGO:00488581230.026
ras protein signal transductionGO:0007265290.026
purine nucleotide catabolic processGO:00061951360.026
regulation of nucleic acid templated transcriptionGO:19035063800.026
positive regulation of protein metabolic processGO:00512471780.026
regulation of hormone levelsGO:00108171870.026
multicellular organism reproductionGO:00325042330.026
response to vitaminGO:00332731310.026
cellular protein localizationGO:00346131220.026
regulation of membrane potentialGO:00423911100.025
regulation of protein kinase activityGO:00458591050.025
blood circulationGO:00080151830.025
cellular ion homeostasisGO:00068731840.025
organic cyclic compound catabolic processGO:19013611750.025
negative regulation of metabolic processGO:00098923310.025
regulation of programmed cell deathGO:00430673410.025
Human
neuron projection developmentGO:00311752730.025
positive regulation of biosynthetic processGO:00098913190.025
regulation of anatomical structure sizeGO:00900661350.025
sexual reproductionGO:00199531480.024
glycosyl compound catabolic processGO:19016581260.024
ribonucleotide metabolic processGO:00092592310.024
regulation of transferase activityGO:00513381230.024
cellular ketone metabolic processGO:0042180510.024
cellular response to organic cyclic compoundGO:00714072020.024
transcription from rna polymerase ii promoterGO:00063662520.024
negative regulation of macromolecule metabolic processGO:00106052600.024
positive regulation of developmental processGO:00510942830.024
regulation of nervous system developmentGO:00519602640.023
response to cytokineGO:00340972150.023
nucleoside triphosphate metabolic processGO:00091411440.023
secretion by cellGO:00329402480.023
lipid metabolic processGO:00066292830.023
negative regulation of signalingGO:00230571570.023
Human
regulation of secretionGO:00510462240.023
positive regulation of cell proliferationGO:00082842490.023
gonad developmentGO:00084061040.023
localization of cellGO:00516742020.023
cellular metal ion homeostasisGO:00068751720.023
positive regulation of phosphorylationGO:00423271770.023
response to organophosphorusGO:00466831020.023
regulation of protein phosphorylationGO:00019321830.023
organophosphate catabolic processGO:00464341480.023
negative regulation of protein metabolic processGO:00512481140.023
brain developmentGO:00074202470.023
organic acid transportGO:00158491160.022
neurological system processGO:00508772190.022
developmental process involved in reproductionGO:00030061590.022
negative regulation of molecular functionGO:00440921330.022
reactive oxygen species biosynthetic processGO:190340980.022
synaptic vesicle endocytosisGO:004848840.022
purine ribonucleotide catabolic processGO:00091541360.022
circulatory system developmentGO:00723591340.022
protein oligomerizationGO:00512591910.022
small molecule catabolic processGO:0044282590.022
response to peptideGO:19016522920.022
cytoskeleton organizationGO:00070101110.022
Human
cell migrationGO:00164771970.022
divalent inorganic cation transportGO:00725111340.021
Human
organic hydroxy compound metabolic processGO:19016151150.021
monocarboxylic acid metabolic processGO:00327871520.021
regulation of purine nucleotide metabolic processGO:19005421150.021
organelle organizationGO:00069962660.021
Human
cellular response to nitrogen compoundGO:19016992100.021
membrane organizationGO:0061024940.021
carbohydrate derivative catabolic processGO:19011361470.021
small gtpase mediated signal transductionGO:0007264360.021
ribonucleoside triphosphate metabolic processGO:00091991410.021
positive regulation of cellular amine metabolic processGO:003324030.021
positive regulation of cell deathGO:00109421840.021
regulation of cellular component organizationGO:00511283680.021
response to peptide hormoneGO:00434342780.020
purine ribonucleoside triphosphate catabolic processGO:00092071220.020
reproductive structure developmentGO:00486081280.020
regulation of multicellular organismal developmentGO:20000263760.020
multicellular organismal reproductive processGO:00486092330.020
learning or memoryGO:0007611900.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
secretionGO:00469033070.020
response to monosaccharideGO:00342841590.020
cell projection organizationGO:00300303020.020
cellular response to organonitrogen compoundGO:00714171970.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
cellular response to cytokine stimulusGO:00713451270.020
positive regulation of gene expressionGO:00106282440.020
positive regulation of cytosolic calcium ion concentrationGO:00072041220.020
negative regulation of transportGO:00510511360.019
actin filament based processGO:0030029860.019
reactive nitrogen species metabolic processGO:200105710.019
regulation of secretion by cellGO:19035302080.019
regulation of cell migrationGO:00303341280.019
cellular macromolecular complex assemblyGO:0034622580.019
synaptic growth at neuromuscular junctionGO:005112410.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
maintenance of locationGO:0051235170.019
negative regulation of phosphorus metabolic processGO:0010563800.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
positive regulation of programmed cell deathGO:00430681570.019
gland developmentGO:00487321550.019
negative regulation of macromolecule biosynthetic processGO:00105581480.019
organonitrogen compound biosynthetic processGO:19015661670.019
carbohydrate derivative biosynthetic processGO:19011371240.019
nucleoside phosphate catabolic processGO:19012921400.018
negative regulation of programmed cell deathGO:00430691830.018
Human
glycosyl compound metabolic processGO:19016571820.018
nucleoside catabolic processGO:00091641260.018
single organism organelle organizationGO:19025891800.018
Human
mapk cascadeGO:00001651400.018
signal transduction by phosphorylationGO:00230141440.018
positive regulation of apoptotic processGO:00430651540.018
purine containing compound catabolic processGO:00725231380.018
regulation of synaptic growth at neuromuscular junctionGO:000858210.018
ribonucleoside catabolic processGO:00424541260.018
gastrulationGO:000736920.018
ovulation cycle processGO:0022602500.018
cellular modified amino acid metabolic processGO:0006575610.018
multicellular organismal signalingGO:0035637440.018
negative regulation of gene expressionGO:00106291990.018
nucleoside triphosphate catabolic processGO:00091431230.018
nucleotide catabolic processGO:00091661390.018
negative regulation of phosphate metabolic processGO:0045936800.018
cellular component movementGO:00069282480.018
Human
g protein coupled receptor signaling pathwayGO:00071862420.017
response to transition metal nanoparticleGO:19902671220.017
negative regulation of biosynthetic processGO:00098901680.017
amine transportGO:0015837570.017
regulation of catalytic activityGO:00507903040.017
ribonucleoside triphosphate catabolic processGO:00092031220.017
nuclear transportGO:0051169490.017
calcium ion homeostasisGO:00550741620.017
rhythmic processGO:00485111560.017
negative regulation of nervous system developmentGO:0051961790.017
circulatory system processGO:00030131830.017
cellular calcium ion homeostasisGO:00068741600.017
metal ion transportGO:00300012890.017
Human
cellular response to acid chemicalGO:0071229750.017
response to growth factorGO:00708481890.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
negative regulation of cell proliferationGO:00082851190.016
cellular response to peptide hormone stimulusGO:00713751200.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
neurotransmitter transportGO:0006836420.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
purine ribonucleoside catabolic processGO:00461301240.016
eye morphogenesisGO:004859240.016
regulation of small gtpase mediated signal transductionGO:0051056480.016
establishment of protein localizationGO:00451841410.016
positive regulation of multicellular organismal processGO:00512403870.016
positive regulation of cellular protein metabolic processGO:00322701670.015
multicellular organism growthGO:003526410.015
regulation of ion transportGO:00432692450.015
Human
memoryGO:0007613540.015
negative regulation of rna biosynthetic processGO:19026791180.015
positive regulation of rna biosynthetic processGO:19026801970.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
action potentialGO:0001508540.015
circadian rhythmGO:0007623880.015
response to decreased oxygen levelsGO:00362932370.015
response to oxidative stressGO:00069791860.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
response to amino acidGO:0043200750.015
regulation of reactive oxygen species biosynthetic processGO:190342650.015
cellular component morphogenesisGO:00329891550.015
neuron deathGO:00709971270.015
response to insulinGO:00328681330.015
regulation of cellular component movementGO:00512701500.015
purine nucleoside triphosphate catabolic processGO:00091461220.015
regulation of cell motilityGO:20001451310.015
response to oxygen levelsGO:00704822650.015
regulation of calcium ion transportGO:0051924770.015
Human
embryonic pattern specificationGO:000988010.015
response to carbohydrateGO:00097431830.014
axon developmentGO:0061564960.014
intracellular protein transportGO:0006886790.014
negative regulation of signal transductionGO:0009968830.014
Human
neuron neuron synaptic transmissionGO:0007270600.014
cell adhesionGO:00071551100.014
calcium ion transportGO:00068161310.014
Human
positive regulation of cellular component organizationGO:00511302000.014
protein heterooligomerizationGO:0051291890.014
biological adhesionGO:00226101100.014
cognitionGO:0050890920.014
muscle system processGO:00030121150.014
chemosensory behaviorGO:000763520.014
regulation of intracellular signal transductionGO:19025312180.014
Human
nucleoside phosphate biosynthetic processGO:19012931020.014
gamete generationGO:00072761240.013
cellular response to external stimulusGO:00714961180.013
development of primary sexual characteristicsGO:00451371070.013
sympathetic nervous system developmentGO:004848510.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
regulation of neuron differentiationGO:00456642080.013
sex differentiationGO:00075481130.013
negative regulation of rna metabolic processGO:00512531230.013
regulation of neurogenesisGO:00507672470.013
chromosome segregationGO:000705920.013
cell morphogenesis involved in neuron differentiationGO:00486671060.013
positive regulation of intracellular signal transductionGO:19025331380.013
Human
divalent metal ion transportGO:00708381320.013
Human
regulation of proteasomal protein catabolic processGO:006113640.013
response to reactive oxygen speciesGO:00003021200.013
cellular lipid metabolic processGO:00442552080.013
response to glucocorticoidGO:00513842230.013
regulation of blood vessel sizeGO:0050880890.013
neural crest cell migrationGO:000175510.013
purine nucleotide biosynthetic processGO:0006164830.013
peptidyl amino acid modificationGO:00181931260.013
regulation of vesicle mediated transportGO:0060627810.013
negative regulation of mitotic cell cycle phase transitionGO:190199130.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
organic hydroxy compound transportGO:0015850770.013
regulation of cell projection organizationGO:00313441750.013
spindle organizationGO:000705120.012
growthGO:00400071650.012
negative regulation of cellular biosynthetic processGO:00313271610.012
regulation of ion transmembrane transportGO:00347651210.012
Human
regulation of neuron projection developmentGO:00109751610.012
response to ketoneGO:19016541820.012
inorganic cation transmembrane transportGO:00986622020.012
Human
female gonad developmentGO:0008585530.012
cell part morphogenesisGO:00329901230.012
lipid storageGO:001991510.012
amino acid transportGO:0006865700.012
negative regulation of apoptotic processGO:00430661810.012
Human
small molecule biosynthetic processGO:00442831240.012
vitamin transportGO:0051180140.012
regulation of mapk cascadeGO:00434081160.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
negative regulation of cell cycle phase transitionGO:190198840.012
receptor mediated endocytosisGO:0006898420.012
regulation of canonical wnt signaling pathwayGO:006082840.012
regulation of cell cycleGO:0051726730.012
regulation of nucleotide catabolic processGO:0030811650.012
purine nucleoside catabolic processGO:00061521240.012
positive regulation of nervous system developmentGO:00519621780.012
vascular process in circulatory systemGO:0003018960.012
negative regulation of ion transportGO:0043271510.012
neuromuscular synaptic transmissionGO:000727420.012
positive regulation of secretionGO:00510471400.012
formation of primary germ layerGO:000170410.012
regulation of nucleotide metabolic processGO:00061401170.012
amino acid transmembrane transportGO:0003333330.012
regulation of anatomical structure morphogenesisGO:00226031410.012
positive regulation of gtpase activityGO:0043547470.012
nucleoside monophosphate metabolic processGO:0009123930.012
actin cytoskeleton organizationGO:0030036730.012
positive regulation of neurogenesisGO:00507691650.012
reproductive system developmentGO:00614581280.012
nucleocytoplasmic transportGO:0006913480.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
digestive system developmentGO:0055123410.011
cytoskeleton dependent cytokinesisGO:006164020.011
positive regulation of kinase activityGO:0033674770.011
developmental growthGO:00485891000.011
protein transportGO:00150311320.011
cardiovascular system developmentGO:00723581340.011
carboxylic acid catabolic processGO:0046395490.011
muscle organ developmentGO:0007517500.011
alpha amino acid catabolic processGO:1901606200.011
cellular protein complex assemblyGO:0043623440.011
hormone secretionGO:00468791150.011
response to toxic substanceGO:00096361330.011
regulation of cellular catabolic processGO:00313291010.011
regulation of hormone secretionGO:00468831060.011
response to glucoseGO:00097491360.011
regulation of cytoskeleton organizationGO:0051493490.011
positive regulation of protein phosphorylationGO:00019341350.011
muscle structure developmentGO:0061061870.011
cell growthGO:00160491040.011
regulation of cell developmentGO:00602842630.011
cell type specific apoptotic processGO:00972851340.011
olfactory learningGO:000835510.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
regulation of peptide transportGO:0090087870.011
regulation of protein localizationGO:0032880810.011
cell morphogenesis involved in differentiationGO:00009041190.011
axis specificationGO:000979840.011
proteolysisGO:00065081750.011
mesoderm formationGO:000170710.011
purine containing compound biosynthetic processGO:0072522850.011
positive regulation of locomotionGO:00400171020.011
regulation of kinase activityGO:00435491170.011
protein localization to organelleGO:0033365570.011
negative regulation of cellular protein metabolic processGO:00322691060.011
adult locomotory behaviorGO:000834440.011
cellular amino acid catabolic processGO:0009063210.011
mechanoreceptor differentiationGO:004249020.011
epithelium developmentGO:0060429960.011
response to ethanolGO:00454711620.010
lipid biosynthetic processGO:00086101280.010
regulation of hydrolase activityGO:00513361430.010
lipid localizationGO:0010876620.010
protein targetingGO:0006605610.010
cell cycleGO:00070491010.010
Human
regulation of neurotransmitter levelsGO:0001505420.010
erk1 and erk2 cascadeGO:0070371480.010
regulation of synaptic plasticityGO:0048167700.010
microtubule organizing center organizationGO:003102310.010
positive regulation of synaptic transmissionGO:0050806620.010
positive regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124120.010
cation transmembrane transportGO:00986552630.010
Human
cytosolic calcium ion homeostasisGO:00514801400.010
regulation of respiratory system processGO:004406510.010
cell morphogenesisGO:00009021420.010
camera type eye morphogenesisGO:004859320.010
positive regulation of protein modification processGO:00314011420.010
response to mechanical stimulusGO:00096121340.010
negative regulation of protein modification processGO:0031400520.010
macroautophagyGO:001623640.010
positive regulation of mapk cascadeGO:0043410920.010

Htt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
Human
disease of anatomical entityDOID:700.029
Human
disease of cellular proliferationDOID:1456600.022
organ system cancerDOID:005068600.022
cancerDOID:16200.022
sensory system diseaseDOID:005015500.019
eye and adnexa diseaseDOID:149200.019
eye diseaseDOID:561400.019
retinal diseaseDOID:567900.016
retinal degenerationDOID:846600.016
neuromuscular diseaseDOID:44000.011
neuropathyDOID:87000.011
inherited metabolic disorderDOID:65500.010
disease of metabolismDOID:001466700.010