Rattus norvegicus

28 known processes

Pola1

polymerase (DNA directed), alpha 1

Pola1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna biosynthetic processGO:00327743800.129
rna metabolic processGO:00160704060.125
regulation of cell proliferationGO:00421273590.102
neuron differentiationGO:00301823680.090
nucleic acid templated transcriptionGO:00976593790.087
response to ethanolGO:00454711620.083
single organism reproductive processGO:00447022970.080
regulation of transcription dna templatedGO:00063553740.079
cell migrationGO:00164771970.078
cellular component movementGO:00069282480.078
organ regenerationGO:00311001010.075
coenzyme metabolic processGO:0006732860.070
regulation of nucleic acid templated transcriptionGO:19035063800.067
tetrahydrofolate metabolic processGO:004665390.066
head developmentGO:00603222470.066
cellular component biogenesisGO:00440853680.065
response to estrogenGO:00436272320.063
cellular catabolic processGO:00442482950.058
regulation of molecular functionGO:00650093980.058
response to corticosteroidGO:00319602350.056
regulation of rna metabolic processGO:00512523910.055
deoxyribonucleoside monophosphate biosynthetic processGO:000915740.055
response to estradiolGO:00323551640.054
nucleoside phosphate metabolic processGO:00067532830.054
carbohydrate derivative metabolic processGO:19011353460.053
rhythmic processGO:00485111560.052
response to other organismGO:00517072200.052
regenerationGO:00310991630.051
purine containing compound metabolic processGO:00725212530.051
cellular response to organic cyclic compoundGO:00714072020.050
single organism biosynthetic processGO:00447113420.050
central nervous system developmentGO:00074173110.050
response to ketoneGO:19016541820.050
reproductionGO:00000032450.048
tissue developmentGO:00098882520.048
apoptotic processGO:00069153810.048
cell motilityGO:00488702020.048
positive regulation of cellular biosynthetic processGO:00313282950.047
response to metal ionGO:00100382530.047
transcription dna templatedGO:00063513770.047
cellular response to oxygen containing compoundGO:19017013860.046
regulation of rna biosynthetic processGO:20011413810.045
cellular response to stressGO:00335542690.045
positive regulation of cell proliferationGO:00082842490.045
pyrimidine nucleobase metabolic processGO:000620680.044
positive regulation of rna metabolic processGO:00512542030.044
response to acid chemicalGO:00011012220.044
brain developmentGO:00074202470.043
secretionGO:00469033070.043
response to nutrientGO:00075842480.042
nucleobase containing small molecule metabolic processGO:00550863160.042
programmed cell deathGO:00125013920.042
sexual reproductionGO:00199531480.041
response to glucocorticoidGO:00513842230.041
macromolecule localizationGO:00330362520.040
positive regulation of nitrogen compound metabolic processGO:00511733340.040
locomotionGO:00400112370.040
response to nutrient levelsGO:00316673700.040
agingGO:00075682410.039
pteridine containing compound metabolic processGO:0042558140.039
reproductive processGO:00224143720.039
positive regulation of multicellular organismal processGO:00512403870.038
positive regulation of rna biosynthetic processGO:19026801970.038
organic acid metabolic processGO:00060822920.038
defense responseGO:00069521940.037
nucleotide metabolic processGO:00091172790.037
cellular response to hormone stimulusGO:00328702470.037
macromolecular complex subunit organizationGO:00439333390.037
positive regulation of cell differentiationGO:00455972170.036
response to extracellular stimulusGO:00099913800.036
organophosphate metabolic processGO:00196373700.036
regulation of catalytic activityGO:00507903040.036
response to decreased oxygen levelsGO:00362932370.035
positive regulation of biosynthetic processGO:00098913190.035
cellular response to endogenous stimulusGO:00714953770.035
regulation of programmed cell deathGO:00430673410.035
cellular response to lipidGO:00713962010.035
positive regulation of developmental processGO:00510942830.035
multi organism reproductive processGO:00447032620.034
multicellular organismal reproductive processGO:00486092330.034
response to woundingGO:00096112540.033
epithelium developmentGO:0060429960.033
negative regulation of cellular metabolic processGO:00313242810.033
response to toxic substanceGO:00096361330.033
aromatic compound catabolic processGO:00194391680.033
negative regulation of apoptotic processGO:00430661810.033
purine ribonucleotide metabolic processGO:00091502270.032
positive regulation of transportGO:00510502450.032
oxoacid metabolic processGO:00434362900.032
organophosphate catabolic processGO:00464341480.032
regulation of apoptotic processGO:00429813350.032
regulation of transcription from rna polymerase ii promoterGO:00063572340.032
regulation of phosphorus metabolic processGO:00511743490.032
dna metabolic processGO:0006259960.032
localization of cellGO:00516742020.032
carboxylic acid metabolic processGO:00197522890.031
transcription from rna polymerase ii promoterGO:00063662520.031
cellular component assemblyGO:00226073600.031
positive regulation of nucleic acid templated transcriptionGO:19035081970.031
female gonad developmentGO:0008585530.030
response to amino acidGO:0043200750.030
regulation of multicellular organismal developmentGO:20000263760.030
deoxyribonucleotide biosynthetic processGO:000926360.030
pyrimidine deoxyribonucleotide metabolic processGO:000921950.030
cell projection organizationGO:00300303020.030
alpha amino acid metabolic processGO:1901605710.030
purine nucleoside triphosphate metabolic processGO:00091441410.030
carbohydrate derivative catabolic processGO:19011361470.030
negative regulation of response to stimulusGO:00485851550.029
regulation of signal transductionGO:00099663180.029
protein complex assemblyGO:00064612630.029
homeostatic processGO:00425923310.029
ribose phosphate metabolic processGO:00196932350.029
positive regulation of nucleobase containing compound metabolic processGO:00459353190.029
development of primary sexual characteristicsGO:00451371070.029
regulation of cell differentiationGO:00455953200.029
chemical homeostasisGO:00488782920.029
purine nucleoside metabolic processGO:00422781690.029
purine nucleotide metabolic processGO:00061632290.029
response to external biotic stimulusGO:00432072210.029
organonitrogen compound catabolic processGO:19015651790.029
response to vitaminGO:00332731310.028
multicellular organism reproductionGO:00325042330.028
ovulation cycle processGO:0022602500.028
protein transportGO:00150311320.027
positive regulation of apoptotic processGO:00430651540.027
regulation of cellular localizationGO:00603412630.027
inflammatory responseGO:00069541500.027
ribonucleotide catabolic processGO:00092611360.027
cellular amine metabolic processGO:0044106380.027
response to hypoxiaGO:00016662310.026
cofactor metabolic processGO:0051186950.026
cation transportGO:00068123820.026
cellular response to nitrogen compoundGO:19016992100.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
anatomical structure morphogenesisGO:00096532980.026
positive regulation of cell deathGO:00109421840.026
forebrain developmentGO:0030900980.026
nucleoside metabolic processGO:00091161790.025
organic cyclic compound catabolic processGO:19013611750.025
negative regulation of macromolecule metabolic processGO:00106052600.025
cellular response to steroid hormone stimulusGO:0071383930.025
response to lipopolysaccharideGO:00324961910.025
ribonucleoside catabolic processGO:00424541260.025
anatomical structure formation involved in morphogenesisGO:0048646830.025
protein localizationGO:00081041910.025
positive regulation of response to stimulusGO:00485842850.024
transformation of host cell by virusGO:001908740.024
response to molecule of bacterial originGO:00022371940.024
purine nucleotide catabolic processGO:00061951360.024
response to bacteriumGO:00096172000.024
development of primary female sexual characteristicsGO:0046545560.024
regulation of secretionGO:00510462240.024
positive regulation of catabolic processGO:0009896780.024
glycosyl compound metabolic processGO:19016571820.024
reproductive system developmentGO:00614581280.023
positive regulation of molecular functionGO:00440932300.023
response to alkaloidGO:00432791320.023
regulation of protein metabolic processGO:00512462890.023
ribonucleoside triphosphate catabolic processGO:00092031220.023
single organism catabolic processGO:00447122830.023
catabolic processGO:00090563510.023
ribonucleoside metabolic processGO:00091191740.023
organic substance catabolic processGO:19015753160.022
positive regulation of protein metabolic processGO:00512471780.022
regulation of cellular component movementGO:00512701500.022
ovulation cycleGO:0042698670.022
female sex differentiationGO:0046660590.022
protein complex subunit organizationGO:00718223020.022
response to oxygen levelsGO:00704822650.022
circadian rhythmGO:0007623880.022
regulation of anatomical structure morphogenesisGO:00226031410.022
response to peptide hormoneGO:00434342780.022
nucleobase containing compound catabolic processGO:00346551520.022
protein complex biogenesisGO:00702712630.022
intracellular signal transductionGO:00355563140.021
regulation of protein localizationGO:0032880810.021
positive regulation of immune system processGO:0002684900.021
cellular response to organonitrogen compoundGO:00714171970.021
regulation of phosphate metabolic processGO:00192203490.021
intracellular transportGO:00469071850.021
folic acid containing compound metabolic processGO:0006760100.021
negative regulation of metabolic processGO:00098923310.021
negative regulation of transcription dna templatedGO:00458921160.021
response to biotic stimulusGO:00096072260.021
developmental process involved in reproductionGO:00030061590.021
positive regulation of phosphate metabolic processGO:00459372620.021
pyrimidine nucleotide biosynthetic processGO:000622190.020
camera type eye developmentGO:0043010480.020
purine ribonucleotide catabolic processGO:00091541360.020
response to inorganic substanceGO:00100353770.020
positive regulation of catalytic activityGO:00430851840.020
immune system processGO:00023762040.020
gamete generationGO:00072761240.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
response to transition metal nanoparticleGO:19902671220.020
negative regulation of signalingGO:00230571570.020
nucleoside phosphate catabolic processGO:19012921400.020
muscle structure developmentGO:0061061870.020
purine ribonucleoside metabolic processGO:00461281680.020
organonitrogen compound biosynthetic processGO:19015661670.020
response to cytokineGO:00340972150.020
tube developmentGO:0035295890.020
regulation of neurogenesisGO:00507672470.019
negative regulation of programmed cell deathGO:00430691830.019
nucleoside triphosphate catabolic processGO:00091431230.019
purine nucleoside triphosphate catabolic processGO:00091461220.019
regulation of cell developmentGO:00602842630.019
heterocycle catabolic processGO:00467001670.019
positive regulation of gene expressionGO:00106282440.019
organ morphogenesisGO:0009887750.019
organophosphate biosynthetic processGO:00904071430.019
positive regulation of secretionGO:00510471400.019
developmental growthGO:00485891000.019
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.019
positive regulation of programmed cell deathGO:00430681570.018
regulation of response to stressGO:00801341260.018
female pregnancyGO:00075651220.018
response to insulinGO:00328681330.018
neurological system processGO:00508772190.018
negative regulation of cellular biosynthetic processGO:00313271610.018
cerebellar purkinje cell layer developmentGO:002168020.018
purine ribonucleoside monophosphate metabolic processGO:0009167840.018
regulation of protein phosphorylationGO:00019321830.018
ribonucleoside triphosphate metabolic processGO:00091991410.018
purine ribonucleoside catabolic processGO:00461301240.018
cellular protein localizationGO:00346131220.018
single organism intracellular transportGO:19025821660.018
regulation of neuron differentiationGO:00456642080.018
deoxyribonucleoside monophosphate metabolic processGO:000916260.017
negative regulation of biosynthetic processGO:00098901680.017
positive regulation of transcription dna templatedGO:00458931970.017
amine metabolic processGO:0009308380.017
cell cycle checkpointGO:000007520.017
negative regulation of cell communicationGO:00106481580.017
double strand break repairGO:000630210.017
skeletal system developmentGO:0001501410.017
nucleoside monophosphate metabolic processGO:0009123930.017
spermatogenesisGO:0007283990.017
ion transmembrane transportGO:00342203650.017
eye morphogenesisGO:004859240.017
regulation of cell projection organizationGO:00313441750.017
cellular amino acid metabolic processGO:00065201070.017
regulation of establishment of protein localizationGO:0070201690.017
establishment of protein localizationGO:00451841410.017
negative regulation of mitotic cell cycle phase transitionGO:190199130.017
cardiovascular system developmentGO:00723581340.016
heart morphogenesisGO:000300730.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
positive regulation of cellular component organizationGO:00511302000.016
negative regulation of gene expressionGO:00106291990.016
secretion by cellGO:00329402480.016
metal ion homeostasisGO:00550651860.016
sex differentiationGO:00075481130.016
nucleoside triphosphate metabolic processGO:00091411440.016
multicellular organism growthGO:003526410.016
ribonucleotide metabolic processGO:00092592310.016
sensory organ developmentGO:0007423740.015
growthGO:00400071650.015
2 deoxyribonucleotide biosynthetic processGO:000926560.015
response to growth factorGO:00708481890.015
male gamete generationGO:0048232990.015
negative regulation of signal transductionGO:0009968830.015
purine containing compound catabolic processGO:00725231380.015
cellular chemical homeostasisGO:00550822470.015
positive regulation of phosphorus metabolic processGO:00105622620.015
positive regulation of cell developmentGO:00107201760.015
response to reactive oxygen speciesGO:00003021200.015
transmembrane transportGO:00550854120.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
atp metabolic processGO:0046034720.015
regulation of protein modification processGO:00313991940.015
positive regulation of neuron projection developmentGO:0010976990.015
actin filament based processGO:0030029860.015
ion homeostasisGO:00508012120.015
nucleotide catabolic processGO:00091661390.015
chemotaxisGO:0006935660.015
circulatory system processGO:00030131830.014
vesicle mediated transportGO:00161921810.014
neuron projection developmentGO:00311752730.014
regulation of cell motilityGO:20001451310.014
positive regulation of cellular component movementGO:00512721020.014
peptidyl amino acid modificationGO:00181931260.014
gland developmentGO:00487321550.014
mitotic cell cycle checkpointGO:000709310.014
proteolysisGO:00065081750.014
wound healingGO:00420601220.014
response to hexoseGO:00097461440.014
lipid metabolic processGO:00066292830.014
organelle organizationGO:00069962660.014
regulation of membrane potentialGO:00423911100.014
cation transmembrane transportGO:00986552630.014
regulation of ion transportGO:00432692450.014
negative regulation of cell cycle phase transitionGO:190198840.014
2 deoxyribonucleotide metabolic processGO:000939490.014
circulatory system developmentGO:00723591340.014
cellular response to cytokine stimulusGO:00713451270.014
protein autophosphorylationGO:0046777660.014
regulation of secretion by cellGO:19035302080.014
negative regulation of rna metabolic processGO:00512531230.014
peptide biosynthetic processGO:004304330.014
response to oxidative stressGO:00069791860.014
multi multicellular organism processGO:00447061380.013
regulation of catabolic processGO:00098941130.013
protein oligomerizationGO:00512591910.013
regulation of cellular amine metabolic processGO:003323880.013
cytokine productionGO:0001816610.013
positive regulation of protein modification processGO:00314011420.013
inorganic cation transmembrane transportGO:00986622020.013
cellular nitrogen compound catabolic processGO:00442701630.013
regulation of hydrolase activityGO:00513361430.013
monovalent inorganic cation transportGO:00156721720.013
neuron developmentGO:00486662860.013
positive regulation of signalingGO:00230562700.013
regulation of fat cell differentiationGO:004559830.013
purine nucleoside monophosphate catabolic processGO:0009128550.013
response to monosaccharideGO:00342841590.013
single organism organelle organizationGO:19025891800.013
positive regulation of phosphorylationGO:00423271770.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
regulation of phosphorylationGO:00423252480.013
cellular cation homeostasisGO:00300031800.013
macromolecular complex assemblyGO:00650032730.013
apoptotic signaling pathwayGO:0097190270.013
cellular response to alcoholGO:0097306870.012
negative regulation of rna biosynthetic processGO:19026791180.012
positive regulation of neurogenesisGO:00507691650.012
regulation of cell migrationGO:00303341280.012
cellular response to peptide hormone stimulusGO:00713751200.012
axis specificationGO:000979840.012
cellular ketone metabolic processGO:0042180510.012
regulation of cellular amino acid metabolic processGO:000652120.012
response to organophosphorusGO:00466831020.012
sensory perceptionGO:00076001010.012
activation of cysteine type endopeptidase activityGO:009720240.012
response to carbohydrateGO:00097431830.012
cytoplasmic transportGO:00164821150.012
positive regulation of cell communicationGO:00106472710.012
positive regulation of cell projection organizationGO:00313461110.012
cytosolic calcium ion homeostasisGO:00514801400.012
negative regulation of cell differentiationGO:0045596990.012
regulation of neuron projection developmentGO:00109751610.012
regulation of immune system processGO:00026821230.012
regulation of hormone levelsGO:00108171870.012
eye developmentGO:0001654500.012
positive regulation of cellular protein metabolic processGO:00322701670.012
regulation of cell morphogenesisGO:0022604770.012
anterior posterior pattern specificationGO:000995210.012
small gtpase mediated signal transductionGO:0007264360.012
regulation of growthGO:00400081050.012
regulation of intracellular transportGO:0032386650.012
protein heterooligomerizationGO:0051291890.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
deoxyribose phosphate biosynthetic processGO:004638560.011
maintenance of locationGO:0051235170.011
regulation of intracellular signal transductionGO:19025312180.011
regulation of neuron deathGO:19012141150.011
pyrimidine nucleotide metabolic processGO:000622090.011
negative regulation of cell deathGO:00605482290.011
single organism cellular localizationGO:19025801020.011
g protein coupled receptor signaling pathwayGO:00071862420.011
regulation of homeostatic processGO:00328441010.011
heart developmentGO:0007507720.011
epithelial cell differentiationGO:0030855710.011
chromosome segregationGO:000705920.011
glycosyl compound catabolic processGO:19016581260.011
response to glucoseGO:00097491360.011
uracil metabolic processGO:001986030.011
telencephalon developmentGO:0021537620.011
inorganic ion transmembrane transportGO:00986602290.011
urogenital system developmentGO:0001655780.011
pyrimidine containing compound biosynthetic processGO:0072528100.011
gliogenesisGO:0042063930.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
regulation of nervous system developmentGO:00519602640.011
regulation of protein transportGO:0051223680.011
reproductive structure developmentGO:00486081280.011
response to purine containing compoundGO:00140741260.011
response to light stimulusGO:0009416520.011
limbic system developmentGO:0021761380.011
cellular response to growth factor stimulusGO:00713631620.011
anion transportGO:00068201780.011
negative regulation of transportGO:00510511360.011
positive regulation of nervous system developmentGO:00519621780.011
cellular macromolecule localizationGO:00707271220.011
deoxyribose phosphate metabolic processGO:001969290.011
taxisGO:0042330670.011
regulation of cellular ketone metabolic processGO:0010565270.011
ras protein signal transductionGO:0007265290.010
protein phosphorylationGO:00064683450.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
organic anion transportGO:00157111320.010
cellular response to abiotic stimulusGO:0071214850.010
respiratory system developmentGO:0060541450.010
negative regulation of organ growthGO:004662130.010
response to radiationGO:00093141370.010
cell adhesionGO:00071551100.010
divalent inorganic cation homeostasisGO:00725071650.010
positive regulation of signal transductionGO:00099671750.010
cell morphogenesisGO:00009021420.010

Pola1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.026
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.010
sensory system diseaseDOID:005015500.010