Rattus norvegicus

17 known processes

Trpm8

transient receptor potential cation channel, subfamily M, member 8

(Aliases: CMR1)

Trpm8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
locomotionGO:00400112370.249
single organism behaviorGO:00447081300.212
Rat
homeostatic processGO:00425923310.212
Rat
cellular chemical homeostasisGO:00550822470.194
Rat
positive regulation of cytosolic calcium ion concentrationGO:00072041220.182
regulation of cell proliferationGO:00421273590.176
response to nutrient levelsGO:00316673700.160
programmed cell deathGO:00125013920.150
Rat
positive regulation of transportGO:00510502450.149
establishment of organ orientationGO:004856110.149
response to inorganic substanceGO:00100353770.142
cellular ion homeostasisGO:00068731840.134
Rat
regulation of hormone levelsGO:00108171870.134
cytosolic calcium ion homeostasisGO:00514801400.131
positive regulation of cell motilityGO:2000147970.127
metal ion homeostasisGO:00550651860.124
Rat
positive regulation of cell proliferationGO:00082842490.122
behaviorGO:00076102050.115
Rat
cellular divalent inorganic cation homeostasisGO:00725031620.115
Rat
regulation of secretionGO:00510462240.113
cellular metal ion homeostasisGO:00068751720.113
Rat
multi multicellular organism processGO:00447061380.113
transmembrane transportGO:00550854120.110
secretionGO:00469033070.096
calcium ion homeostasisGO:00550741620.095
cellular homeostasisGO:00197252520.092
Rat
regulation of cell motilityGO:20001451310.088
neurological system processGO:00508772190.084
Rat
skeletal system developmentGO:0001501410.084
localization of cellGO:00516742020.084
organic anion transportGO:00157111320.083
cellular calcium ion homeostasisGO:00068741600.083
cellular response to endogenous stimulusGO:00714953770.082
positive regulation of cellular biosynthetic processGO:00313282950.080
regulation of secretion by cellGO:19035302080.077
positive regulation of synaptic transmission cholinergicGO:003222460.077
nitrogen compound transportGO:00717052290.075
tissue developmentGO:00098882520.075
secretion by cellGO:00329402480.074
positive regulation of biosynthetic processGO:00098913190.074
regulation of cellular localizationGO:00603412630.074
reproductionGO:00000032450.071
response to lipopolysaccharideGO:00324961910.070
regulation of multicellular organismal developmentGO:20000263760.068
regulation of signal transductionGO:00099663180.064
cognitionGO:0050890920.063
Rat
positive regulation of cellular component movementGO:00512721020.063
reproductive processGO:00224143720.063
regulation of programmed cell deathGO:00430673410.063
Rat
positive regulation of secretion by cellGO:19035321280.062
negative regulation of rna metabolic processGO:00512531230.060
regulation of cell migrationGO:00303341280.059
ion homeostasisGO:00508012120.058
Rat
negative regulation of transcription dna templatedGO:00458921160.058
signal releaseGO:00230611450.057
response to estrogenGO:00436272320.057
regulation of blood pressureGO:0008217830.056
response to ketoneGO:19016541820.056
urinary bladder smooth muscle contractionGO:001483240.055
hormone transportGO:00099141210.055
chemical homeostasisGO:00488782920.055
Rat
smooth muscle cell proliferationGO:0048659770.054
synaptic transmissionGO:00072682350.054
multicellular organism reproductionGO:00325042330.053
hormone secretionGO:00468791150.053
cell migrationGO:00164771970.051
ovulation cycle processGO:0022602500.051
response to reactive oxygen speciesGO:00003021200.050
multicellular organismal reproductive processGO:00486092330.050
response to extracellular stimulusGO:00099913800.049
cellular cation homeostasisGO:00300031800.049
Rat
regulation of cellular component movementGO:00512701500.049
neuron deathGO:00709971270.048
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.048
micturitionGO:006007340.047
oxoacid metabolic processGO:00434362900.046
cellular response to nitrogen compoundGO:19016992100.046
insulin secretionGO:0030073690.046
tube developmentGO:0035295890.045
positive regulation of cell migrationGO:0030335960.045
negative regulation of macromolecule biosynthetic processGO:00105581480.045
negative regulation of secretion by cellGO:1903531720.044
divalent inorganic cation homeostasisGO:00725071650.044
Rat
positive regulation of developmental processGO:00510942830.043
cation homeostasisGO:00550801950.042
Rat
negative regulation of rna biosynthetic processGO:19026791180.042
peptide hormone secretionGO:0030072840.041
single organism reproductive processGO:00447022970.040
positive regulation of secretionGO:00510471400.040
rna biosynthetic processGO:00327743800.040
eye developmentGO:0001654500.039
positive regulation of nervous system developmentGO:00519621780.039
regulation of saliva secretionGO:004687730.039
angiotensin mediated drinking behaviorGO:000305120.038
cellular component movementGO:00069282480.038
multi organism reproductive processGO:00447032620.038
cell motilityGO:00488702020.037
regulation of cell differentiationGO:00455953200.037
negative regulation of macromolecule metabolic processGO:00106052600.037
positive regulation of lymphocyte proliferationGO:0050671200.037
cellular amine metabolic processGO:0044106380.037
ion transmembrane transportGO:00342203650.037
negative regulation of glutamate secretionGO:001405090.037
response to estradiolGO:00323551640.036
regulation of hormone secretionGO:00468831060.036
response to metal ionGO:00100382530.036
negative regulation of cell deathGO:00605482290.036
negative regulation of cell communicationGO:00106481580.036
response to mechanical stimulusGO:00096121340.036
cellular response to lipidGO:00713962010.036
neuron differentiationGO:00301823680.036
ovulation cycleGO:0042698670.036
positive regulation of gene expressionGO:00106282440.035
circulatory system processGO:00030131830.035
peptide transportGO:0015833970.035
regulation of nucleic acid templated transcriptionGO:19035063800.034
positive regulation of cell differentiationGO:00455972170.034
anion transportGO:00068201780.034
response to nicotineGO:0035094510.034
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.034
urinary tract smooth muscle contractionGO:001484840.033
cellular response to growth factor stimulusGO:00713631620.033
steroid metabolic processGO:0008202730.033
regulation of smooth muscle cell proliferationGO:0048660750.032
muscle cell proliferationGO:0033002840.032
calcium ion transportGO:00068161310.031
Rat
negative regulation of programmed cell deathGO:00430691830.031
head developmentGO:00603222470.031
amine metabolic processGO:0009308380.031
action potentialGO:0001508540.030
divalent metal ion transportGO:00708381320.030
Rat
brain developmentGO:00074202470.030
negative regulation of cellular metabolic processGO:00313242810.030
negative regulation of gene expressionGO:00106291990.030
positive regulation of nitrogen compound metabolic processGO:00511733340.030
regulation of peptide hormone secretionGO:0090276800.030
cellular response to oxygen containing compoundGO:19017013860.030
macromolecular complex subunit organizationGO:00439333390.030
response to oxygen levelsGO:00704822650.029
acid secretionGO:0046717480.029
reproductive system developmentGO:00614581280.029
leukocyte migrationGO:0050900380.029
regulation of neuron deathGO:19012141150.029
development of primary sexual characteristicsGO:00451371070.028
negative regulation of nitrogen compound metabolic processGO:00511721610.028
cell cell signalingGO:00072673350.028
positive regulation of transcription dna templatedGO:00458931970.028
central nervous system developmentGO:00074173110.027
cellular response to organonitrogen compoundGO:00714171970.027
synaptic vesicle amine transportGO:001584230.027
regulation of epithelial cell proliferationGO:0050678490.027
gonad developmentGO:00084061040.027
eosinophil migrationGO:007267730.027
regulation of nervous system developmentGO:00519602640.027
organic acid transportGO:00158491160.027
apoptotic processGO:00069153810.026
Rat
positive regulation of programmed cell deathGO:00430681570.026
Rat
response to external biotic stimulusGO:00432072210.026
response to woundingGO:00096112540.026
negative regulation of nucleic acid templated transcriptionGO:19035071170.026
carboxylic acid metabolic processGO:00197522890.025
regulation of molecular functionGO:00650093980.025
positive regulation of nucleic acid templated transcriptionGO:19035081970.025
negative regulation of multicellular organismal processGO:00512412030.025
synaptic transmission cholinergicGO:0007271110.025
regulation of anatomical structure morphogenesisGO:00226031410.025
negative regulation of metabolic processGO:00098923310.025
negative regulation of developmental processGO:00510931250.025
response to molecule of bacterial originGO:00022371940.025
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.025
negative regulation of transportGO:00510511360.025
positive regulation of multicellular organismal processGO:00512403870.025
positive regulation of mononuclear cell proliferationGO:0032946200.024
positive regulation of nucleobase containing compound metabolic processGO:00459353190.024
cellular response to cytokine stimulusGO:00713451270.024
neuron neuron synaptic transmissionGO:0007270600.024
response to oxidative stressGO:00069791860.024
positive regulation of rna metabolic processGO:00512542030.024
peptide secretionGO:0002790860.024
blood circulationGO:00080151830.023
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.023
cellular response to drugGO:0035690300.023
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.023
positive regulation of rna biosynthetic processGO:19026801970.023
establishment of anatomical structure orientationGO:004856010.023
positive regulation of response to stimulusGO:00485842850.022
growthGO:00400071650.022
regulation of immune system processGO:00026821230.022
protein complex assemblyGO:00064612630.022
positive regulation of phosphorus metabolic processGO:00105622620.022
developmental process involved in reproductionGO:00030061590.022
negative regulation of response to stimulusGO:00485851550.022
positive regulation of signal transductionGO:00099671750.022
rhythmic processGO:00485111560.022
cellular component assemblyGO:00226073600.022
positive regulation of cell communicationGO:00106472710.021
regulation of rna biosynthetic processGO:20011413810.021
nucleic acid templated transcriptionGO:00976593790.021
heart processGO:0003015570.020
anatomical structure morphogenesisGO:00096532980.020
regulation of rna metabolic processGO:00512523910.020
multicellular organismal response to stressGO:0033555250.020
tissue remodelingGO:0048771400.020
regulation of cell developmentGO:00602842630.020
cellular response to stressGO:00335542690.020
regulation of organic acid transportGO:0032890350.020
peptidyl amino acid modificationGO:00181931260.020
regulation of transcription from rna polymerase ii promoterGO:00063572340.020
response to hexoseGO:00097461440.020
cellular response to external stimulusGO:00714961180.020
vascular process in circulatory systemGO:0003018960.020
regulation of leukocyte migrationGO:0002685240.019
response to nutrientGO:00075842480.019
response to peptide hormoneGO:00434342780.019
positive regulation of signalingGO:00230562700.019
ribose phosphate metabolic processGO:00196932350.019
regulation of feeding behaviorGO:0060259140.019
learning or memoryGO:0007611900.019
Rat
female pregnancyGO:00075651220.019
sensory perception of painGO:0019233730.018
regulation of ion transportGO:00432692450.018
cation transportGO:00068123820.018
Rat
organic acid metabolic processGO:00060822920.018
positive regulation of epithelial cell proliferationGO:0050679320.018
response to growth factorGO:00708481890.018
negative regulation of biosynthetic processGO:00098901680.018
positive regulation of neurogenesisGO:00507691650.018
female sex differentiationGO:0046660590.018
response to acid chemicalGO:00011012220.018
g protein coupled receptor signaling pathwayGO:00071862420.018
neuron developmentGO:00486662860.018
response to cytokineGO:00340972150.018
response to vitaminGO:00332731310.018
regulation of anion transportGO:0044070430.018
mechanoreceptor differentiationGO:004249020.018
protein complex biogenesisGO:00702712630.017
regulation of membrane potentialGO:00423911100.017
positive regulation of immune system processGO:0002684900.017
reproductive structure developmentGO:00486081280.017
hematopoietic progenitor cell differentiationGO:000224420.017
angiogenesisGO:0001525530.017
positive regulation of lymphocyte activationGO:0051251250.017
response to alkaloidGO:00432791320.017
protein oligomerizationGO:00512591910.017
response to painGO:0048265110.017
learningGO:0007612330.017
negative regulation of signalingGO:00230571570.017
microglial cell activationGO:0001774140.016
cellular response to lipopolysaccharideGO:0071222550.016
positive regulation of protein metabolic processGO:00512471780.016
smooth muscle contraction involved in micturitionGO:006008310.016
negative regulation of neurogenesisGO:0050768780.016
positive regulation of peptide hormone secretionGO:0090277500.016
defense responseGO:00069521940.016
angioblast cell migrationGO:003547610.016
sex differentiationGO:00075481130.016
reactive oxygen species biosynthetic processGO:190340980.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
protein localizationGO:00081041910.016
regulation of neurogenesisGO:00507672470.016
regulation of blood vessel sizeGO:0050880890.016
regulation of protein modification processGO:00313991940.016
cellular response to organic cyclic compoundGO:00714072020.016
regulation of cellular component organizationGO:00511283680.016
cellular amino acid metabolic processGO:00065201070.015
regulation of immunoglobulin productionGO:000263740.015
epithelial cell proliferationGO:0050673540.015
glutamate secretionGO:0014047190.015
spinal cord developmentGO:0021510270.015
positive regulation of fibroblast proliferationGO:0048146150.015
lymphocyte activationGO:0046649430.015
regulation of anatomical structure sizeGO:00900661350.015
macromolecule localizationGO:00330362520.015
response to decreased oxygen levelsGO:00362932370.015
regulation of cellular amine metabolic processGO:003323880.015
circadian sleep wake cycle processGO:0022410210.015
immune system processGO:00023762040.015
positive regulation of hormone secretionGO:0046887650.015
lipid metabolic processGO:00066292830.015
steroid biosynthetic processGO:0006694480.015
cellular response to molecule of bacterial originGO:0071219560.015
carboxylic acid transportGO:00469421150.014
negative regulation of cell differentiationGO:0045596990.014
negative regulation of ion transportGO:0043271510.014
inner ear receptor cell differentiationGO:006011320.014
positive regulation of molecular functionGO:00440932300.014
axis specificationGO:000979840.014
regulation of protein metabolic processGO:00512462890.014
smooth muscle cell migrationGO:0014909360.014
negative regulation of secretionGO:0051048820.014
amide transportGO:00428861050.014
positive regulation of saliva secretionGO:004687830.014
regulation of vasculature developmentGO:1901342440.014
positive regulation of phosphate metabolic processGO:00459372620.014
cell growthGO:00160491040.014
heart contractionGO:0060047570.014
stress activated protein kinase signaling cascadeGO:0031098370.014
acute inflammatory responseGO:0002526580.014
intracellular signal transductionGO:00355563140.013
positive regulation of homeostatic processGO:0032846490.013
inorganic ion transmembrane transportGO:00986602290.013
Rat
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
cellular component biogenesisGO:00440853680.013
negative regulation of organ growthGO:004662130.013
response to tumor necrosis factorGO:0034612560.013
coenzyme metabolic processGO:0006732860.013
protein phosphorylationGO:00064683450.013
Rat
urogenital system developmentGO:0001655780.013
organ morphogenesisGO:0009887750.013
regulation of cell projection organizationGO:00313441750.013
reactive nitrogen species metabolic processGO:200105710.013
lipid biosynthetic processGO:00086101280.013
protein homooligomerizationGO:0051260910.013
cell chemotaxisGO:0060326310.013
epithelial cell differentiationGO:0030855710.013
macrophage activationGO:0042116150.013
glucose homeostasisGO:0042593750.013
negative regulation of long term synaptic potentiationGO:190027210.013
positive regulation of locomotionGO:00400171020.013
saliva secretionGO:004654130.013
vasculature developmentGO:0001944700.013
regulation of locomotionGO:00400121480.013
palate developmentGO:006002120.013
sensory perception of bitter tasteGO:005091340.013
transcription from rna polymerase ii promoterGO:00063662520.013
epithelium developmentGO:0060429960.013
inflammatory responseGO:00069541500.013
positive regulation of leukocyte proliferationGO:0070665200.013
regulation of cellular amino acid metabolic processGO:000652120.013
lymphocyte proliferationGO:0046651290.012
tachykinin receptor signaling pathwayGO:000721730.012
dendrite developmentGO:0016358720.012
negative regulation of chronic inflammatory responseGO:000267720.012
sexual reproductionGO:00199531480.012
response to biotic stimulusGO:00096072260.012
organic hydroxy compound metabolic processGO:19016151150.012
positive regulation of catalytic activityGO:00430851840.012
regulatory t cell differentiationGO:004506620.012
mapk cascadeGO:00001651400.012
ossificationGO:0001503700.012
cell projection organizationGO:00300303020.012
eye morphogenesisGO:004859240.012
cellular response to metal ionGO:0071248550.012
monovalent inorganic cation transportGO:00156721720.012
regulation of homeostatic processGO:00328441010.012
anterior posterior pattern specificationGO:000995210.012
regulation of phosphate metabolic processGO:00192203490.012
generation of ovulation cycle rhythmGO:006011220.012
regulation of catalytic activityGO:00507903040.012
response to radiationGO:00093141370.012
Rat
response to chromateGO:004668730.012
regulation of apoptotic processGO:00429813350.012
Rat
embryonic skeletal system morphogenesisGO:004870430.012
ventral spinal cord developmentGO:002151730.012
carbohydrate derivative metabolic processGO:19011353460.011
regulation of body fluid levelsGO:0050878900.011
positive regulation of cell developmentGO:00107201760.011
sensory organ developmentGO:0007423740.011
stress activated mapk cascadeGO:0051403350.011
cellular response to alcoholGO:0097306870.011
dopamine metabolic processGO:0042417120.011
regulation of synaptic transmission cholinergicGO:003222260.011
regulation of system processGO:00440572080.011
positive regulation of cell deathGO:00109421840.011
Rat
regulation of metal ion transportGO:00109591180.011
organonitrogen compound biosynthetic processGO:19015661670.011
somatostatin secretionGO:007025370.011
negative regulation of nervous system developmentGO:0051961790.011
response to amineGO:0014075460.011
positive regulation of phosphorylationGO:00423271770.011
response to peptideGO:19016522920.011
intracellular receptor signaling pathwayGO:0030522350.011
organelle organizationGO:00069962660.011
response to ethanolGO:00454711620.011
regulation of isotype switchingGO:004519110.011
positive regulation of somatostatin secretionGO:009027440.011
leukocyte activationGO:0045321760.011
divalent inorganic cation transportGO:00725111340.011
Rat
renal system developmentGO:0072001670.011
positive regulation of peptide secretionGO:0002793520.011
positive regulation of insulin secretionGO:0032024360.011
cellular response to hormone stimulusGO:00328702470.011
regulation of synaptic transmissionGO:00508041410.011
jnk cascadeGO:0007254280.011
respiratory system developmentGO:0060541450.011
regulation of behaviorGO:0050795610.011
organ regenerationGO:00311001010.011
metanephric tubule morphogenesisGO:007217320.011
odontogenesisGO:0042476320.010
regulation of response to external stimulusGO:00321011060.010
developmental growthGO:00485891000.010
hormone metabolic processGO:0042445690.010
negative regulation of apoptotic processGO:00430661810.010
regulation of acute inflammatory responseGO:0002673230.010
gamete generationGO:00072761240.010
single organism biosynthetic processGO:00447113420.010
regulation of phosphorus metabolic processGO:00511743490.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
regulation of peptide transportGO:0090087870.010
positive regulation of immunoglobulin productionGO:000263940.010
mononuclear cell proliferationGO:0032943290.010
operant conditioningGO:003510640.010
ameboidal type cell migrationGO:0001667260.010
response to hydrogen peroxideGO:0042542890.010
lipid transportGO:0006869610.010
response to calcium ionGO:0051592590.010
positive regulation of vascular permeabilityGO:004311770.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010

Trpm8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
nervous system diseaseDOID:86300.041
sensory system diseaseDOID:005015500.019
kidney diseaseDOID:55700.012
renal tubular transport diseaseDOID:44700.012
urinary system diseaseDOID:1800.012