Rattus norvegicus

177 known processes

Srd5a1

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

(Aliases: S5AR 1,MGC156498)

Srd5a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
halogenated hydrocarbon metabolic processGO:004219740.712
organic acid metabolic processGO:00060822920.626
Rat
oxoacid metabolic processGO:00434362900.429
Rat
carboxylic acid metabolic processGO:00197522890.308
Rat
monocarboxylic acid metabolic processGO:00327871520.291
lipid metabolic processGO:00066292830.272
fatty acid metabolic processGO:0006631990.263
response to inorganic substanceGO:00100353770.259
organic acid biosynthetic processGO:0016053830.199
chlorinated hydrocarbon metabolic processGO:004219640.188
response to metal ionGO:00100382530.146
response to bacteriumGO:00096172000.138
lipid biosynthetic processGO:00086101280.133
cellular catabolic processGO:00442482950.128
response to insulinGO:00328681330.124
organic anion transportGO:00157111320.124
carboxylic acid biosynthetic processGO:0046394830.120
apoptotic processGO:00069153810.119
response to other organismGO:00517072200.117
cellular amino acid metabolic processGO:00065201070.114
response to oxidative stressGO:00069791860.105
response to biotic stimulusGO:00096072260.102
coenzyme metabolic processGO:0006732860.101
cellular lipid metabolic processGO:00442552080.099
response to external biotic stimulusGO:00432072210.097
small molecule biosynthetic processGO:00442831240.094
regulation of apoptotic processGO:00429813350.088
response to acid chemicalGO:00011012220.088
anion transportGO:00068201780.086
amine metabolic processGO:0009308380.078
catabolic processGO:00090563510.077
Rat
central nervous system developmentGO:00074173110.076
sulfur compound metabolic processGO:0006790700.076
fatty acid derivative metabolic processGO:1901568380.075
cellular amine metabolic processGO:0044106380.074
response to ethanolGO:00454711620.068
response to ketoneGO:19016541820.066
behaviorGO:00076102050.065
cell projection organizationGO:00300303020.064
single organism catabolic processGO:00447122830.063
Rat
regulation of nervous system developmentGO:00519602640.063
programmed cell deathGO:00125013920.063
protein maturationGO:0051604680.062
neuron developmentGO:00486662860.062
lipid transportGO:0006869610.062
regulation of cellular amine metabolic processGO:003323880.061
negative regulation of gene expressionGO:00106291990.061
glycerolipid metabolic processGO:0046486670.059
cofactor metabolic processGO:0051186950.059
agingGO:00075682410.058
negative regulation of metabolic processGO:00098923310.058
rhythmic processGO:00485111560.058
regulation of cell differentiationGO:00455953200.057
response to peptide hormoneGO:00434342780.057
carboxylic acid transportGO:00469421150.057
reactive nitrogen species metabolic processGO:200105710.056
regulation of programmed cell deathGO:00430673410.055
nucleobase containing small molecule metabolic processGO:00550863160.054
neuron differentiationGO:00301823680.053
regulation of rna biosynthetic processGO:20011413810.053
cell cell signalingGO:00072673350.053
brain developmentGO:00074202470.053
icosanoid metabolic processGO:0006690380.053
regulation of cellular component organizationGO:00511283680.052
regulation of cellular amino acid metabolic processGO:000652120.051
positive regulation of cell communicationGO:00106472710.050
transcription dna templatedGO:00063513770.049
regulation of cellular protein metabolic processGO:00322682670.047
dopamine metabolic processGO:0042417120.047
monovalent inorganic cation transportGO:00156721720.047
steroid metabolic processGO:0008202730.047
organic acid transportGO:00158491160.046
macromolecule localizationGO:00330362520.045
multicellular organism reproductionGO:00325042330.045
organic hydroxy compound metabolic processGO:19016151150.044
protein phosphorylationGO:00064683450.044
carbohydrate derivative metabolic processGO:19011353460.044
anatomical structure morphogenesisGO:00096532980.043
cell motilityGO:00488702020.043
fluorene metabolic processGO:001891710.043
ion homeostasisGO:00508012120.042
positive regulation of cell deathGO:00109421840.042
positive regulation of developmental processGO:00510942830.042
response to lipopolysaccharideGO:00324961910.042
growthGO:00400071650.041
regulation of cellular ketone metabolic processGO:0010565270.040
cellular modified amino acid metabolic processGO:0006575610.039
chemical homeostasisGO:00488782920.039
cardiovascular system developmentGO:00723581340.039
cellular response to lipidGO:00713962010.039
circulatory system developmentGO:00723591340.039
response to mechanical stimulusGO:00096121340.039
negative regulation of molecular functionGO:00440921330.038
protein complex subunit organizationGO:00718223020.037
cellular component assemblyGO:00226073600.037
regulation of locomotionGO:00400121480.037
neuron projection developmentGO:00311752730.037
inflammatory responseGO:00069541500.037
regulation of molecular functionGO:00650093980.036
long chain fatty acid metabolic processGO:0001676320.036
locomotionGO:00400112370.036
acute phase responseGO:0006953200.036
cellular ketone metabolic processGO:0042180510.036
unsaturated fatty acid metabolic processGO:0033559390.036
regulation of protein metabolic processGO:00512462890.035
localization of cellGO:00516742020.035
defense responseGO:00069521940.035
single organism organelle organizationGO:19025891800.035
organophosphate metabolic processGO:00196373700.035
multi organism reproductive processGO:00447032620.035
regulation of cellular component movementGO:00512701500.034
proteolysisGO:00065081750.034
regulation of cell developmentGO:00602842630.034
response to molecule of bacterial originGO:00022371940.034
response to cytokineGO:00340972150.033
reactive oxygen species biosynthetic processGO:190340980.033
cellular component biogenesisGO:00440853680.033
cell migrationGO:00164771970.033
regulation of nucleic acid templated transcriptionGO:19035063800.033
regulation of hormone levelsGO:00108171870.032
cellular response to peptide hormone stimulusGO:00713751200.032
secretionGO:00469033070.032
homeostatic processGO:00425923310.032
smooth muscle cell proliferationGO:0048659770.031
response to alkaloidGO:00432791320.031
single organism biosynthetic processGO:00447113420.031
response to transition metal nanoparticleGO:19902671220.031
cellular modified amino acid biosynthetic processGO:0042398180.031
negative regulation of protein metabolic processGO:00512481140.031
neutral lipid metabolic processGO:0006638210.031
cellular component movementGO:00069282480.031
response to peptideGO:19016522920.031
regulation of neuron differentiationGO:00456642080.030
response to testosteroneGO:0033574550.030
positive regulation of cellular component organizationGO:00511302000.030
positive regulation of apoptotic processGO:00430651540.030
regulation of membrane potentialGO:00423911100.030
phenol containing compound metabolic processGO:0018958300.030
linoleic acid metabolic processGO:004365140.030
response to woundingGO:00096112540.029
organic substance catabolic processGO:19015753160.029
Rat
response to estrogenGO:00436272320.029
response to reactive oxygen speciesGO:00003021200.029
negative regulation of programmed cell deathGO:00430691830.029
regulation of tube sizeGO:0035150890.029
liver developmentGO:0001889900.029
cellular response to stressGO:00335542690.029
rna metabolic processGO:00160704060.029
regulation of synaptic transmissionGO:00508041410.029
negative regulation of developmental processGO:00510931250.028
regulation of transcription dna templatedGO:00063553740.028
positive regulation of nitrogen compound metabolic processGO:00511733340.028
regulation of secretionGO:00510462240.027
regulation of multicellular organismal developmentGO:20000263760.027
intracellular signal transductionGO:00355563140.027
reproductionGO:00000032450.027
positive regulation of cell differentiationGO:00455972170.027
negative regulation of cellular metabolic processGO:00313242810.027
positive regulation of nucleic acid templated transcriptionGO:19035081970.027
regulation of signal transductionGO:00099663180.027
monocarboxylic acid transportGO:0015718520.027
signal transduction by phosphorylationGO:00230141440.026
regulation of cellular localizationGO:00603412630.026
cellular metal ion homeostasisGO:00068751720.026
regulation of blood pressureGO:0008217830.026
gland developmentGO:00487321550.026
negative regulation of nitrogen compound metabolic processGO:00511721610.026
regulation of cell proliferationGO:00421273590.025
cellular response to oxygen containing compoundGO:19017013860.025
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.025
organic hydroxy compound biosynthetic processGO:1901617510.025
fatty acid biosynthetic processGO:0006633330.025
positive regulation of rna biosynthetic processGO:19026801970.025
response to temperature stimulusGO:0009266940.025
cation transportGO:00068123820.025
cellular response to organic cyclic compoundGO:00714072020.025
positive regulation of phosphorylationGO:00423271770.025
muscle cell proliferationGO:0033002840.025
ribose phosphate metabolic processGO:00196932350.025
organonitrogen compound biosynthetic processGO:19015661670.025
cell growthGO:00160491040.024
positive regulation of programmed cell deathGO:00430681570.024
regulation of neurogenesisGO:00507672470.024
cellular homeostasisGO:00197252520.024
negative regulation of cell differentiationGO:0045596990.024
negative regulation of catalytic activityGO:00430861030.024
positive regulation of cellular amino acid metabolic processGO:004576410.024
cellular component morphogenesisGO:00329891550.024
axon developmentGO:0061564960.024
positive regulation of transportGO:00510502450.023
positive regulation of cellular biosynthetic processGO:00313282950.023
regulation of protein modification processGO:00313991940.023
positive regulation of cellular amine metabolic processGO:003324030.023
circadian rhythmGO:0007623880.023
regulation of anatomical structure morphogenesisGO:00226031410.023
regulation of reactive oxygen species biosynthetic processGO:190342650.023
developmental growthGO:00485891000.023
negative regulation of cellular protein metabolic processGO:00322691060.023
purine nucleotide metabolic processGO:00061632290.023
nicotine metabolic processGO:001893310.023
peptidyl amino acid modificationGO:00181931260.023
negative regulation of cell developmentGO:0010721820.022
macromolecular complex subunit organizationGO:00439333390.022
phenylpropanoid catabolic processGO:004627130.022
regulation of catalytic activityGO:00507903040.022
reactive oxygen species metabolic processGO:0072593370.022
glial cell differentiationGO:0010001650.022
negative regulation of cell communicationGO:00106481580.022
aromatic compound catabolic processGO:00194391680.022
regulation of hydrolase activityGO:00513361430.022
response to toxic substanceGO:00096361330.022
benzene containing compound metabolic processGO:0042537220.022
Rat
organonitrogen compound catabolic processGO:19015651790.022
positive regulation of neurogenesisGO:00507691650.022
cell morphogenesis involved in neuron differentiationGO:00486671060.022
negative regulation of apoptotic processGO:00430661810.022
positive regulation of cell developmentGO:00107201760.021
response to decreased oxygen levelsGO:00362932370.021
regulation of phosphate metabolic processGO:00192203490.021
neuron projection morphogenesisGO:00488121220.021
protein processingGO:0016485680.021
response to extracellular stimulusGO:00099913800.021
cellular response to organonitrogen compoundGO:00714171970.021
single organism intracellular transportGO:19025821660.021
small molecule catabolic processGO:0044282590.020
ion transmembrane transportGO:00342203650.020
blood circulationGO:00080151830.020
regulation of proteasomal protein catabolic processGO:006113640.020
response to amino acidGO:0043200750.020
arachidonic acid metabolic processGO:0019369200.020
catecholamine metabolic processGO:0006584190.020
regulation of rna metabolic processGO:00512523910.020
regulation of ion transportGO:00432692450.020
epithelial cell proliferationGO:0050673540.020
ribonucleoside metabolic processGO:00091191740.020
reproductive processGO:00224143720.019
nucleic acid templated transcriptionGO:00976593790.019
cellular response to peptideGO:19016531330.019
mapk cascadeGO:00001651400.019
multicellular organismal reproductive processGO:00486092330.019
cell part morphogenesisGO:00329901230.019
regulation of immune system processGO:00026821230.019
action potentialGO:0001508540.019
negative regulation of protein maturationGO:1903318470.019
regulation of response to stressGO:00801341260.018
immune system processGO:00023762040.018
synaptic transmissionGO:00072682350.018
muscle structure developmentGO:0061061870.018
regulation of homeostatic processGO:00328441010.018
single organism reproductive processGO:00447022970.018
purine ribonucleotide metabolic processGO:00091502270.018
organic cyclic compound catabolic processGO:19013611750.018
Rat
metal ion homeostasisGO:00550651860.018
protein complex biogenesisGO:00702712630.018
regulation of intracellular signal transductionGO:19025312180.018
establishment of tissue polarityGO:000716420.018
naphthalene metabolic processGO:001893120.018
multicellular organism growthGO:003526410.018
nitrogen compound transportGO:00717052290.018
gap junction assemblyGO:001626420.018
coumarin catabolic processGO:004622630.018
response to carbohydrateGO:00097431830.018
regulation of reactive oxygen species metabolic processGO:2000377260.018
positive regulation of protein phosphorylationGO:00019341350.017
acid secretionGO:0046717480.017
acute inflammatory responseGO:0002526580.017
positive regulation of signalingGO:00230562700.017
glycosyl compound metabolic processGO:19016571820.017
sexual reproductionGO:00199531480.017
pyridine containing compound metabolic processGO:0072524320.017
nucleoside triphosphate catabolic processGO:00091431230.017
cellular response to growth factor stimulusGO:00713631620.017
positive regulation of nervous system developmentGO:00519621780.017
negative regulation of macromolecule metabolic processGO:00106052600.017
terpenoid metabolic processGO:0006721370.017
positive regulation of biosynthetic processGO:00098913190.017
monocarboxylic acid biosynthetic processGO:0072330480.016
response to nicotineGO:0035094510.016
transcription from rna polymerase ii promoterGO:00063662520.016
pteridine containing compound metabolic processGO:0042558140.016
purine containing compound metabolic processGO:00725212530.016
lipid storageGO:001991510.016
positive regulation of secretionGO:00510471400.016
positive regulation of gene expressionGO:00106282440.016
innate immune responseGO:0045087350.016
immune responseGO:00069551040.016
learning or memoryGO:0007611900.016
nucleoside triphosphate metabolic processGO:00091411440.016
purine ribonucleoside triphosphate catabolic processGO:00092071220.016
cell morphogenesisGO:00009021420.016
prostaglandin transportGO:001573280.016
regulation of smooth muscle cell proliferationGO:0048660750.016
positive regulation of lipid biosynthetic processGO:0046889250.016
positive regulation of signal transductionGO:00099671750.016
negative regulation of transportGO:00510511360.016
negative regulation of multicellular organismal processGO:00512412030.016
positive regulation of nucleobase containing compound metabolic processGO:00459353190.016
protein targetingGO:0006605610.016
negative regulation of cellular component organizationGO:0051129830.016
regulation of cell motilityGO:20001451310.016
cation homeostasisGO:00550801950.016
response to nutrient levelsGO:00316673700.016
cellular response to external stimulusGO:00714961180.016
heterocycle catabolic processGO:00467001670.015
rna biosynthetic processGO:00327743800.015
regulation of anatomical structure sizeGO:00900661350.015
negative regulation of response to stimulusGO:00485851550.015
gliogenesisGO:0042063930.015
single organism behaviorGO:00447081300.015
regulation of cell growthGO:0001558850.015
camera type eye morphogenesisGO:004859320.015
response to nutrientGO:00075842480.015
positive regulation of macromolecule biosynthetic processGO:00105572470.015
response to corticosteroneGO:0051412400.015
sensory perceptionGO:00076001010.015
vesicle localizationGO:0051648330.015
fatty acid transportGO:0015908250.015
positive regulation of catalytic activityGO:00430851840.015
acylglycerol metabolic processGO:0006639210.015
axonogenesisGO:0007409710.015
olfactory bulb interneuron differentiationGO:002188910.015
secretion by cellGO:00329402480.015
cell projection morphogenesisGO:00488581230.015
adult locomotory behaviorGO:000834440.015
neutral lipid biosynthetic processGO:004646070.015
ribonucleotide metabolic processGO:00092592310.014
regulation of lipid biosynthetic processGO:0046890380.014
nucleotide metabolic processGO:00091172790.014
regulation of calcium ion transportGO:0051924770.014
regulation of peptide transportGO:0090087870.014
response to sulfur dioxideGO:001047730.014
cellular response to insulin stimulusGO:0032869810.014
regulation of protein phosphorylationGO:00019321830.014
anterior posterior pattern specificationGO:000995210.014
purine nucleoside metabolic processGO:00422781690.014
amide transportGO:00428861050.014
small gtpase mediated signal transductionGO:0007264360.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
sterol homeostasisGO:005509230.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
epoxygenase p450 pathwayGO:001937310.014
positive regulation of neuron differentiationGO:00456661260.014
axis specificationGO:000979840.014
negative regulation of transcription regulatory region dna bindingGO:200067820.014
cellular cation homeostasisGO:00300031800.014
response to cesium ionGO:001016420.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
positive regulation of transcription dna templatedGO:00458931970.014
positive regulation of neuron projection developmentGO:0010976990.013
transmission of nerve impulseGO:0019226420.013
response to monosaccharideGO:00342841590.013
oxidation reduction processGO:00551143040.013
naphthalene containing compound metabolic processGO:009042020.013
positive regulation of organic acid transportGO:0032892220.013
protein complex assemblyGO:00064612630.013
regulation of fatty acid metabolic processGO:0019217180.013
cellular response to cytokine stimulusGO:00713451270.013
regulation of proteolysisGO:0030162660.013
isoquinoline alkaloid metabolic processGO:003307620.013
positive regulation of smooth muscle cell proliferationGO:0048661510.013
positive regulation of cellular protein metabolic processGO:00322701670.013
regulation of peptidase activityGO:0052547550.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
negative regulation of cell deathGO:00605482290.013
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.013
cellular response to hormone stimulusGO:00328702470.013
cardiac conductionGO:006133720.013
regulation of protein maturationGO:1903317500.013
protein autophosphorylationGO:0046777660.013
regulation of synaptic transmission glutamatergicGO:0051966260.013
cellular amino acid biosynthetic processGO:0008652320.013
head developmentGO:00603222470.013
lipid localizationGO:0010876620.013
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.013
regulation of neuron projection developmentGO:00109751610.013
regulation of protein processingGO:0070613500.013
transmembrane transportGO:00550854120.012
drug catabolic processGO:004273710.012
vesicle mediated transportGO:00161921810.012
cellular lipid catabolic processGO:0044242370.012
response to glucoseGO:00097491360.012
regulation of cell projection organizationGO:00313441750.012
positive regulation of cell projection organizationGO:00313461110.012
negative regulation of neurogenesisGO:0050768780.012
alkaloid metabolic processGO:000982030.012
cellular ion homeostasisGO:00068731840.012
nucleoside phosphate metabolic processGO:00067532830.012
regulation of blood circulationGO:19035221100.012
alpha amino acid metabolic processGO:1901605710.012
negative regulation of response to woundingGO:1903035230.012
positive regulation of molecular functionGO:00440932300.012
lipid catabolic processGO:0016042460.012
Rat
amine transportGO:0015837570.012
positive regulation of cell proliferationGO:00082842490.012
response to estradiolGO:00323551640.012
regulation of cellular catabolic processGO:00313291010.012
positive regulation of response to stimulusGO:00485842850.012
positive regulation of multicellular organismal processGO:00512403870.012
regulation of system processGO:00440572080.012
response to hydrogen peroxideGO:0042542890.012
female pregnancyGO:00075651220.012
cellular response to oxidative stressGO:0034599760.012
organelle organizationGO:00069962660.012
regulation of phosphorus metabolic processGO:00511743490.011
regulation of metal ion transportGO:00109591180.011
macromolecular complex assemblyGO:00650032730.011
regulation of growthGO:00400081050.011
morphogenesis of embryonic epitheliumGO:001633130.011
response to hypoxiaGO:00016662310.011
metaphase anaphase transition of mitotic cell cycleGO:000709110.011
peptide metabolic processGO:0006518320.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
establishment of organelle localizationGO:0051656370.011
regulation of phosphorylationGO:00423252480.011
intracellular transportGO:00469071850.011
response to campGO:0051591910.011
negative regulation of phosphorus metabolic processGO:0010563800.011
positive regulation of synaptic transmissionGO:0050806620.011
protein oligomerizationGO:00512591910.011
dicarboxylic acid transportGO:0006835340.011
purine containing compound catabolic processGO:00725231380.011
dendrite developmentGO:0016358720.011
purine nucleoside monophosphate metabolic processGO:0009126840.011
developmental process involved in reproductionGO:00030061590.011
regulation of cell migrationGO:00303341280.011
serotonin metabolic processGO:004242830.011
positive regulation of phosphorus metabolic processGO:00105622620.011
isoprenoid metabolic processGO:0006720450.011
nucleotide catabolic processGO:00091661390.011
positive regulation of protein metabolic processGO:00512471780.011
peptidyl tyrosine phosphorylationGO:0018108720.011
cytoplasmic transportGO:00164821150.011
tube developmentGO:0035295890.010
positive regulation of protein modification processGO:00314011420.010
positive regulation of secretion by cellGO:19035321280.010
catechol containing compound metabolic processGO:0009712190.010
amino acid transportGO:0006865700.010
response to ionizing radiationGO:0010212590.010
positive regulation of phosphate metabolic processGO:00459372620.010
protein transportGO:00150311320.010
cell morphogenesis involved in differentiationGO:00009041190.010
cellular response to steroid hormone stimulusGO:0071383930.010
positive regulation of reactive oxygen species metabolic processGO:2000379160.010
blood vessel morphogenesisGO:0048514580.010
negative regulation of rna biosynthetic processGO:19026791180.010
heart morphogenesisGO:000300730.010
hormone catabolic processGO:004244720.010
collateral sproutingGO:004866820.010
erk1 and erk2 cascadeGO:0070371480.010
rna localizationGO:000640340.010

Srd5a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.015
disease of cellular proliferationDOID:1456600.014