Rattus norvegicus

17 known processes

Limk2

LIM domain kinase 2

(Aliases: Limk2b,Link2)

Limk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.128
carboxylic acid metabolic processGO:00197522890.095
organic acid metabolic processGO:00060822920.078
protein phosphorylationGO:00064683450.071
intracellular signal transductionGO:00355563140.070
cellular amino acid metabolic processGO:00065201070.067
lipid metabolic processGO:00066292830.064
protein localizationGO:00081041910.063
regulation of phosphorylationGO:00423252480.057
positive regulation of signalingGO:00230562700.055
regulation of phosphorus metabolic processGO:00511743490.054
positive regulation of cell communicationGO:00106472710.054
negative regulation of cellular metabolic processGO:00313242810.053
cellular component movementGO:00069282480.053
positive regulation of nitrogen compound metabolic processGO:00511733340.052
cellular ketone metabolic processGO:0042180510.050
positive regulation of response to stimulusGO:00485842850.048
regulation of rna biosynthetic processGO:20011413810.047
tissue developmentGO:00098882520.047
Fly
positive regulation of phosphorus metabolic processGO:00105622620.047
catabolic processGO:00090563510.046
regulation of cell proliferationGO:00421273590.046
homeostatic processGO:00425923310.045
positive regulation of signal transductionGO:00099671750.044
regulation of phosphate metabolic processGO:00192203490.044
mapk cascadeGO:00001651400.044
cell cell signalingGO:00072673350.043
regulation of cellular amino acid metabolic processGO:000652120.043
regulation of cellular ketone metabolic processGO:0010565270.042
lipid biosynthetic processGO:00086101280.042
regulation of cell differentiationGO:00455953200.042
Fly
response to extracellular stimulusGO:00099913800.042
single organism biosynthetic processGO:00447113420.042
positive regulation of developmental processGO:00510942830.041
regulation of rna metabolic processGO:00512523910.041
macromolecule localizationGO:00330362520.041
regulation of protein phosphorylationGO:00019321830.040
regulation of cellular amine metabolic processGO:003323880.040
response to oxygen levelsGO:00704822650.040
transcription from rna polymerase ii promoterGO:00063662520.040
cellular response to stressGO:00335542690.040
regulation of molecular functionGO:00650093980.039
regulation of cellular component organizationGO:00511283680.039
Fly
cellular catabolic processGO:00442482950.039
cellular amine metabolic processGO:0044106380.039
nucleic acid templated transcriptionGO:00976593790.038
cellular response to oxygen containing compoundGO:19017013860.038
amine metabolic processGO:0009308380.037
positive regulation of cellular amino acid metabolic processGO:004576410.037
positive regulation of molecular functionGO:00440932300.037
regulation of signal transductionGO:00099663180.037
chemical homeostasisGO:00488782920.036
response to peptideGO:19016522920.036
rna metabolic processGO:00160704060.035
positive regulation of multicellular organismal processGO:00512403870.035
response to decreased oxygen levelsGO:00362932370.034
response to corticosteroidGO:00319602350.034
response to nutrient levelsGO:00316673700.034
cell projection organizationGO:00300303020.034
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353190.034
macromolecular complex assemblyGO:00650032730.033
anatomical structure morphogenesisGO:00096532980.033
Fly
programmed cell deathGO:00125013920.033
regulation of catalytic activityGO:00507903040.033
positive regulation of phosphate metabolic processGO:00459372620.032
positive regulation of phosphorylationGO:00423271770.032
cation homeostasisGO:00550801950.032
positive regulation of cellular biosynthetic processGO:00313282950.031
transcription dna templatedGO:00063513770.031
cellular response to endogenous stimulusGO:00714953770.031
cellular component assemblyGO:00226073600.031
Rat Fly
response to inorganic substanceGO:00100353770.031
Worm
cellular component biogenesisGO:00440853680.031
Rat Fly
cell migrationGO:00164771970.031
regulation of intracellular signal transductionGO:19025312180.031
secretionGO:00469033070.030
central nervous system developmentGO:00074173110.030
synaptic transmissionGO:00072682350.030
negative regulation of multicellular organismal processGO:00512412030.030
positive regulation of biosynthetic processGO:00098913190.030
regulation of programmed cell deathGO:00430673410.030
positive regulation of cellular amine metabolic processGO:003324030.029
negative regulation of metabolic processGO:00098923310.029
regulation of transcription from rna polymerase ii promoterGO:00063572340.029
rna biosynthetic processGO:00327743800.029
positive regulation of intracellular signal transductionGO:19025331380.029
organelle organizationGO:00069962660.029
Rat Fly
regulation of cellular protein metabolic processGO:00322682670.029
neuron differentiationGO:00301823680.028
Fly
localization of cellGO:00516742020.028
regulation of apoptotic processGO:00429813350.028
positive regulation of cell deathGO:00109421840.028
positive regulation of catalytic activityGO:00430851840.028
positive regulation of cell differentiationGO:00455972170.028
regulation of cellular localizationGO:00603412630.027
apoptotic processGO:00069153810.027
growthGO:00400071650.027
Fly
response to acid chemicalGO:00011012220.027
neuron projection developmentGO:00311752730.027
Fly
response to monosaccharideGO:00342841590.027
cation transportGO:00068123820.026
cellular lipid metabolic processGO:00442552080.026
organic substance catabolic processGO:19015753160.026
response to glucoseGO:00097491360.026
regulation of protein modification processGO:00313991940.026
negative regulation of developmental processGO:00510931250.026
response to hypoxiaGO:00016662310.026
regulation of nucleic acid templated transcriptionGO:19035063800.026
regulation of multicellular organismal developmentGO:20000263760.026
Fly
regulation of hormone levelsGO:00108171870.026
regulation of neurogenesisGO:00507672470.026
Fly
organophosphate metabolic processGO:00196373700.025
carbohydrate derivative metabolic processGO:19011353460.025
positive regulation of protein phosphorylationGO:00019341350.025
response to woundingGO:00096112540.025
agingGO:00075682410.024
Worm
negative regulation of cell communicationGO:00106481580.024
monocarboxylic acid metabolic processGO:00327871520.024
ion transmembrane transportGO:00342203650.024
regulation of proteasomal protein catabolic processGO:006113640.024
enzyme linked receptor protein signaling pathwayGO:00071671160.024
ion homeostasisGO:00508012120.024
single organism reproductive processGO:00447022970.024
Mouse Rat
regulation of cell projection organizationGO:00313441750.023
Fly
response to carbohydrateGO:00097431830.023
regulation of neuron differentiationGO:00456642080.023
Fly
positive regulation of mapk cascadeGO:0043410920.023
gastrulationGO:000736920.023
negative regulation of signalingGO:00230571570.023
positive regulation of protein modification processGO:00314011420.023
response to other organismGO:00517072200.023
cell motilityGO:00488702020.023
immune system processGO:00023762040.022
reproductive processGO:00224143720.022
Mouse Rat
defense responseGO:00069521940.022
regulation of neuron projection developmentGO:00109751610.022
Fly
multicellular organismal reproductive processGO:00486092330.022
Mouse Rat
protein oligomerizationGO:00512591910.022
cell morphogenesisGO:00009021420.022
Fly
transmembrane transportGO:00550854120.021
single organism catabolic processGO:00447122830.021
vesicle mediated transportGO:00161921810.021
organic acid transportGO:00158491160.021
regulation of cell developmentGO:00602842630.021
Fly
cellular response to peptideGO:19016531330.021
positive regulation of cell proliferationGO:00082842490.021
protein complex assemblyGO:00064612630.021
response to peptide hormoneGO:00434342780.021
purine containing compound metabolic processGO:00725212530.020
regulation of response to stressGO:00801341260.020
negative regulation of gene expressionGO:00106291990.020
positive regulation of protein metabolic processGO:00512471780.020
reproductionGO:00000032450.020
Mouse Rat
cellular response to peptide hormone stimulusGO:00713751200.020
cellular homeostasisGO:00197252520.020
positive regulation of nervous system developmentGO:00519621780.020
axis specificationGO:000979840.020
regenerationGO:00310991630.020
multicellular organism growthGO:003526410.020
peptidyl amino acid modificationGO:00181931260.020
anion transportGO:00068201780.020
intracellular transportGO:00469071850.020
positive regulation of cellular protein metabolic processGO:00322701670.020
proteolysisGO:00065081750.020
regulation of transferase activityGO:00513381230.020
cellular cation homeostasisGO:00300031800.019
response to nutrientGO:00075842480.019
metal ion homeostasisGO:00550651860.019
negative regulation of macromolecule metabolic processGO:00106052600.019
regulation of system processGO:00440572080.019
cellular chemical homeostasisGO:00550822470.019
regulation of ion transportGO:00432692450.019
regulation of kinase activityGO:00435491170.019
positive regulation of apoptotic processGO:00430651540.019
signal transduction by phosphorylationGO:00230141440.019
response to metal ionGO:00100382530.019
Worm
cellular response to nitrogen compoundGO:19016992100.019
small gtpase mediated signal transductionGO:0007264360.019
response to hexoseGO:00097461440.019
cellular response to hormone stimulusGO:00328702470.019
negative regulation of cell proliferationGO:00082851190.019
cellular macromolecule localizationGO:00707271220.018
response to glucocorticoidGO:00513842230.018
regulation of cell migrationGO:00303341280.018
ribose phosphate metabolic processGO:00196932350.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
positive regulation of programmed cell deathGO:00430681570.018
divalent inorganic cation homeostasisGO:00725071650.018
response to bacteriumGO:00096172000.018
cell morphogenesis involved in differentiationGO:00009041190.018
Fly
negative regulation of nitrogen compound metabolic processGO:00511721610.018
regulation of secretion by cellGO:19035302080.018
epithelium developmentGO:0060429960.018
Fly
negative regulation of neuron differentiationGO:0045665620.017
regulation of synaptic transmissionGO:00508041410.017
positive regulation of gene expressionGO:00106282440.017
positive regulation of cell developmentGO:00107201760.017
regulation of nervous system developmentGO:00519602640.017
Fly
regulation of cellular component movementGO:00512701500.017
positive regulation of neurogenesisGO:00507691650.017
protein complex biogenesisGO:00702712630.017
regulation of mapk cascadeGO:00434081160.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
neurological system processGO:00508772190.017
positive regulation of cellular component organizationGO:00511302000.017
embryonic pattern specificationGO:000988010.017
cellular response to growth factor stimulusGO:00713631620.017
positive regulation of transportGO:00510502450.017
regulation of cell motilityGO:20001451310.017
macromolecular complex subunit organizationGO:00439333390.017
negative regulation of biosynthetic processGO:00098901680.017
purine nucleotide metabolic processGO:00061632290.017
neuron developmentGO:00486662860.017
Fly
fatty acid metabolic processGO:0006631990.017
cellular ion homeostasisGO:00068731840.016
regulation of protein metabolic processGO:00512462890.016
action potentialGO:0001508540.016
negative regulation of rna metabolic processGO:00512531230.016
regulation of protein kinase activityGO:00458591050.016
response to insulinGO:00328681330.016
cation transmembrane transportGO:00986552630.016
eye morphogenesisGO:004859240.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
negative regulation of transcription dna templatedGO:00458921160.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
ras protein signal transductionGO:0007265290.016
formation of primary germ layerGO:000170410.016
negative regulation of transportGO:00510511360.016
locomotionGO:00400112370.016
blood circulationGO:00080151830.016
regulation of canonical wnt signaling pathwayGO:006082840.016
heart morphogenesisGO:000300730.015
cellular component morphogenesisGO:00329891550.015
Fly
protein complex subunit organizationGO:00718223020.015
organonitrogen compound biosynthetic processGO:19015661670.015
regulation of catabolic processGO:00098941130.015
cytoplasmic transportGO:00164821150.015
peptidyl tyrosine phosphorylationGO:0018108720.015
nucleoside phosphate metabolic processGO:00067532830.015
multicellular organism reproductionGO:00325042330.015
Mouse Rat
heterocycle catabolic processGO:00467001670.015
negative regulation of rna biosynthetic processGO:19026791180.015
regulation of transcription dna templatedGO:00063553740.015
response to growth factorGO:00708481890.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
circulatory system processGO:00030131830.015
inflammatory responseGO:00069541500.015
calcium ion homeostasisGO:00550741620.015
response to biotic stimulusGO:00096072260.015
nucleobase containing small molecule metabolic processGO:00550863160.015
negative regulation of programmed cell deathGO:00430691830.015
metal ion transportGO:00300012890.015
gamete generationGO:00072761240.015
Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.014
negative regulation of nervous system developmentGO:0051961790.014
single organism intracellular transportGO:19025821660.014
chromosome segregationGO:000705920.014
sexual reproductionGO:00199531480.014
Mouse Rat
regulation of locomotionGO:00400121480.014
negative regulation of phosphorus metabolic processGO:0010563800.014
purine ribonucleotide metabolic processGO:00091502270.014
organophosphate biosynthetic processGO:00904071430.014
regulation of membrane potentialGO:00423911100.014
regulation of cellular response to stressGO:0080135490.014
negative regulation of response to stimulusGO:00485851550.014
brain developmentGO:00074202470.014
negative regulation of catalytic activityGO:00430861030.014
peptidyl tyrosine modificationGO:0018212720.014
negative regulation of cellular component organizationGO:0051129830.014
head developmentGO:00603222470.014
multi organism reproductive processGO:00447032620.014
Mouse Rat
adult locomotory behaviorGO:000834440.014
cellular response to lipidGO:00713962010.014
cellular response to external stimulusGO:00714961180.014
response to external biotic stimulusGO:00432072210.014
regulation of growthGO:00400081050.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
negative regulation of cell deathGO:00605482290.014
negative regulation of cellular biosynthetic processGO:00313271610.013
secretion by cellGO:00329402480.013
positive regulation of neuron differentiationGO:00456661260.013
negative regulation of signal transductionGO:0009968830.013
response to starvationGO:0042594590.013
positive regulation of transferase activityGO:0051347810.013
cell part morphogenesisGO:00329901230.013
Fly
nitrogen compound transportGO:00717052290.013
carboxylic acid transportGO:00469421150.013
cellular response to organic cyclic compoundGO:00714072020.013
ossificationGO:0001503700.013
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.013
anterior posterior pattern specificationGO:000995210.013
hormone metabolic processGO:0042445690.013
dna metabolic processGO:0006259960.013
cell growthGO:00160491040.013
negative regulation of apoptotic processGO:00430661810.013
sensory perceptionGO:00076001010.013
purine ribonucleoside metabolic processGO:00461281680.013
hormone transportGO:00099141210.013
negative regulation of cell differentiationGO:0045596990.013
establishment of protein localizationGO:00451841410.013
positive regulation of cell projection organizationGO:00313461110.013
oxidation reduction processGO:00551143040.012
cellular nitrogen compound catabolic processGO:00442701630.012
cellular response to extracellular stimulusGO:0031668730.012
dephosphorylationGO:0016311980.012
cellular response to insulin stimulusGO:0032869810.012
cellular response to organonitrogen compoundGO:00714171970.012
negative regulation of phosphate metabolic processGO:0045936800.012
regulation of anatomical structure morphogenesisGO:00226031410.012
Fly
organonitrogen compound catabolic processGO:19015651790.012
protein autophosphorylationGO:0046777660.012
single organism cellular localizationGO:19025801020.012
single organism organelle organizationGO:19025891800.012
Rat Fly
cytosolic calcium ion homeostasisGO:00514801400.012
negative regulation of molecular functionGO:00440921330.012
protein homooligomerizationGO:0051260910.012
nucleoside metabolic processGO:00091161790.012
regulation of cellular catabolic processGO:00313291010.012
regulation of anatomical structure sizeGO:00900661350.012
developmental growthGO:00485891000.012
Fly
cellular protein localizationGO:00346131220.012
organic anion transportGO:00157111320.012
cardiac conductionGO:006133720.012
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.012
response to ketoneGO:19016541820.012
protein transportGO:00150311320.012
cellular metal ion homeostasisGO:00068751720.012
response to molecule of bacterial originGO:00022371940.012
regulation of secretionGO:00510462240.012
positive regulation of kinase activityGO:0033674770.012
embryonic skeletal system morphogenesisGO:004870430.011
protein heterooligomerizationGO:0051291890.011
carbohydrate metabolic processGO:00059751300.011
response to oxidative stressGO:00069791860.011
cardiovascular system developmentGO:00723581340.011
nucleotide metabolic processGO:00091172790.011
small molecule biosynthetic processGO:00442831240.011
developmental process involved in reproductionGO:00030061590.011
purine nucleoside metabolic processGO:00422781690.011
cell projection morphogenesisGO:00488581230.011
Fly
response to lipopolysaccharideGO:00324961910.011
cell cycle checkpointGO:000007520.011
activation of protein kinase activityGO:0032147470.011
monosaccharide metabolic processGO:0005996610.011
hepaticobiliary system developmentGO:0061008900.011
neuron deathGO:00709971270.011
regulation of cellular component biogenesisGO:0044087860.011
response to vitaminGO:00332731310.011
regulation of cell cycleGO:0051726730.011
regulation of purine nucleotide metabolic processGO:19005421150.011
negative regulation of cell developmentGO:0010721820.011
positive regulation of rna biosynthetic processGO:19026801970.011
g protein coupled receptor signaling pathwayGO:00071862420.011
lipid transportGO:0006869610.011
regulation of stem cell differentiationGO:200073620.011
response to axon injuryGO:0048678590.011
regulation of nucleotide metabolic processGO:00061401170.011
dendrite developmentGO:0016358720.011
positive regulation of rna metabolic processGO:00512542030.011
coenzyme metabolic processGO:0006732860.011
circulatory system developmentGO:00723591340.011
regulation of neuron deathGO:19012141150.011
embryonic axis specificationGO:000057810.011
response to radiationGO:00093141370.011
organ morphogenesisGO:0009887750.011
Fly
regulation of metal ion transportGO:00109591180.011
hexose metabolic processGO:0019318580.010
nucleoside phosphate catabolic processGO:19012921400.010
response to transition metal nanoparticleGO:19902671220.010
Worm
organophosphate catabolic processGO:00464341480.010
response to mechanical stimulusGO:00096121340.010
organic cyclic compound catabolic processGO:19013611750.010
gland developmentGO:00487321550.010
camera type eye morphogenesisGO:004859320.010
regulation of cell growthGO:0001558850.010
neuronal action potentialGO:0019228350.010
neural crest cell differentiationGO:001403320.010
negative regulation of neurogenesisGO:0050768780.010
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.010
mesoderm developmentGO:000749820.010
reactive nitrogen species metabolic processGO:200105710.010
positive regulation of transcription dna templatedGO:00458931970.010
inorganic ion transmembrane transportGO:00986602290.010
organic hydroxy compound metabolic processGO:19016151150.010
defense response to gram negative bacteriumGO:005082930.010
regulation of organelle organizationGO:0033043800.010
monovalent inorganic cation transportGO:00156721720.010

Limk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
cardiovascular system diseaseDOID:128700.016
disease of cellular proliferationDOID:1456600.013
disease of metabolismDOID:001466700.012
musculoskeletal system diseaseDOID:1700.012
organ system cancerDOID:005068600.011
cancerDOID:16200.011
gastrointestinal system cancerDOID:311900.011