IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Limk1

LIM domain kinase 1

Entrez: 65172
Ensembl: ENSRNOG00000001470
RGD: 62055
UniProtKB: G3V663

Process Predictions
Disease Predictions

Limk1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
anatomical structure morphogenesis	GO:0009653	298	0.200	Mouse Fly
neuron differentiation	GO:0030182	368	0.196	Mouse Fly
positive regulation of multicellular organismal process	GO:0051240	387	0.196	Mouse
cellular amino acid metabolic process	GO:0006520	107	0.125
regulation of cell differentiation	GO:0045595	320	0.122	Mouse Fly
regulation of cell proliferation	GO:0042127	359	0.120
organelle organization	GO:0006996	266	0.116	Human Mouse Rat Fly
protein phosphorylation	GO:0006468	345	0.113	Human Rat Worm Fly
cellular response to oxygen containing compound	GO:1901701	386	0.109
regulation of protein modification process	GO:0031399	194	0.108	Human
neurological system process	GO:0050877	219	0.105
positive regulation of cell communication	GO:0010647	271	0.103
cell migration	GO:0016477	197	0.103
neuron projection development	GO:0031175	273	0.099	Mouse Fly
positive regulation of cell differentiation	GO:0045597	217	0.099	Mouse
positive regulation of nervous system development	GO:0051962	178	0.097	Mouse
regulation of neuron differentiation	GO:0045664	208	0.092	Mouse Fly
macromolecular complex subunit organization	GO:0043933	339	0.090	Human Mouse
response to wounding	GO:0009611	254	0.090
regulation of nucleic acid templated transcription	GO:1903506	380	0.084
rna metabolic process	GO:0016070	406	0.080
regulation of cell projection organization	GO:0031344	175	0.078	Mouse Fly
positive regulation of neurogenesis	GO:0050769	165	0.077	Mouse
regulation of rna biosynthetic process	GO:2001141	381	0.075
response to hypoxia	GO:0001666	231	0.074
cellular chemical homeostasis	GO:0055082	247	0.074
response to peptide hormone	GO:0043434	278	0.071
homeostatic process	GO:0042592	331	0.070
organic substance catabolic process	GO:1901575	316	0.068
regulation of phosphorylation	GO:0042325	248	0.067
single organism organelle organization	GO:1902589	180	0.065	Human Mouse Rat Fly
oxoacid metabolic process	GO:0043436	290	0.065
axon development	GO:0061564	96	0.064	Mouse Fly
cell projection organization	GO:0030030	302	0.063	Mouse Fly
regulation of transcription dna templated	GO:0006355	374	0.063
catabolic process	GO:0009056	351	0.063
nucleic acid templated transcription	GO:0097659	379	0.062
regulation of neurogenesis	GO:0050767	247	0.062	Mouse Fly
protein complex assembly	GO:0006461	263	0.060
positive regulation of signaling	GO:0023056	270	0.060
regulation of multicellular organismal development	GO:2000026	376	0.059	Mouse Fly
protein complex biogenesis	GO:0070271	263	0.058
macromolecular complex assembly	GO:0065003	273	0.058
response to peptide	GO:1901652	292	0.058
organic acid metabolic process	GO:0006082	292	0.058
rna biosynthetic process	GO:0032774	380	0.057
cellular response to hormone stimulus	GO:0032870	247	0.055
positive regulation of protein metabolic process	GO:0051247	178	0.055
positive regulation of response to stimulus	GO:0048584	285	0.055
calcium ion homeostasis	GO:0055074	162	0.054
negative regulation of multicellular organismal process	GO:0051241	203	0.054
regulation of phosphorus metabolic process	GO:0051174	349	0.054
cytoskeleton organization	GO:0007010	111	0.054	Human Mouse Rat Fly
regulation of catalytic activity	GO:0050790	304	0.054	Human
head development	GO:0060322	247	0.054
response to nutrient levels	GO:0031667	370	0.053
regulation of cellular protein metabolic process	GO:0032268	267	0.053	Human
response to glucocorticoid	GO:0051384	223	0.053
single organism catabolic process	GO:0044712	283	0.052
response to nutrient	GO:0007584	248	0.051
regulation of neuron projection development	GO:0010975	161	0.051	Mouse Fly
amine metabolic process	GO:0009308	38	0.051
response to extracellular stimulus	GO:0009991	380	0.050
cellular component assembly	GO:0022607	360	0.050	Human Mouse Rat Fly
regulation of cellular amine metabolic process	GO:0033238	8	0.050
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.049	Mouse Fly
cellular protein localization	GO:0034613	122	0.049
regulation of apoptotic process	GO:0042981	335	0.048
regulation of molecular function	GO:0065009	398	0.048	Human
response to inorganic substance	GO:0010035	377	0.048	Worm
localization of cell	GO:0051674	202	0.047
positive regulation of neuron differentiation	GO:0045666	126	0.046	Mouse
cellular response to stress	GO:0033554	269	0.046
cellular metal ion homeostasis	GO:0006875	172	0.046
regulation of cellular component organization	GO:0051128	368	0.046	Human Mouse Fly
positive regulation of phosphorus metabolic process	GO:0010562	262	0.046
positive regulation of developmental process	GO:0051094	283	0.046	Mouse
transcription dna templated	GO:0006351	377	0.046
regulation of signal transduction	GO:0009966	318	0.045
programmed cell death	GO:0012501	392	0.045
response to acid chemical	GO:0001101	222	0.045
regulation of programmed cell death	GO:0043067	341	0.045
negative regulation of metabolic process	GO:0009892	331	0.045	Human
response to oxygen levels	GO:0070482	265	0.044
positive regulation of signal transduction	GO:0009967	175	0.043
cellular catabolic process	GO:0044248	295	0.043
regulation of anatomical structure size	GO:0090066	135	0.043	Mouse
cell part morphogenesis	GO:0032990	123	0.042	Mouse Fly
intracellular signal transduction	GO:0035556	314	0.042
positive regulation of cell proliferation	GO:0008284	249	0.042
cellular component biogenesis	GO:0044085	368	0.041	Human Mouse Rat Fly
neuron death	GO:0070997	127	0.041
regulation of protein phosphorylation	GO:0001932	183	0.041
cellular amine metabolic process	GO:0044106	38	0.040
cellular homeostasis	GO:0019725	252	0.040
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.040
regulation of locomotion	GO:0040012	148	0.040
regulation of anatomical structure morphogenesis	GO:0022603	141	0.039	Mouse Fly
positive regulation of peptide hormone secretion	GO:0090277	50	0.039
cellular calcium ion homeostasis	GO:0006874	160	0.038
regulation of phosphate metabolic process	GO:0019220	349	0.038
response to decreased oxygen levels	GO:0036293	237	0.038
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.038
amide transport	GO:0042886	105	0.038
blood circulation	GO:0008015	183	0.038
negative regulation of signaling	GO:0023057	157	0.038
reproductive process	GO:0022414	372	0.037	Rat
gland development	GO:0048732	155	0.037
regulation of peptide secretion	GO:0002791	82	0.037
regulation of cell development	GO:0060284	263	0.037	Mouse Fly
regulation of neuron apoptotic process	GO:0043523	83	0.036
regulation of dendrite development	GO:0050773	59	0.036
negative regulation of cell communication	GO:0010648	158	0.036
apoptotic process	GO:0006915	381	0.036
regulation of cellular localization	GO:0060341	263	0.036
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.036
protein localization	GO:0008104	191	0.035
response to ethanol	GO:0045471	162	0.035
regulation of peptide transport	GO:0090087	87	0.035
positive regulation of cell development	GO:0010720	176	0.035	Mouse
circulatory system process	GO:0003013	183	0.035
single organism cellular localization	GO:1902580	102	0.035
multicellular organism reproduction	GO:0032504	233	0.035	Rat
locomotion	GO:0040011	237	0.034
brain development	GO:0007420	247	0.034
cell motility	GO:0048870	202	0.034
positive regulation of catalytic activity	GO:0043085	184	0.034
positive regulation of protein phosphorylation	GO:0001934	135	0.034
positive regulation of molecular function	GO:0044093	230	0.034
anterior posterior pattern specification	GO:0009952	1	0.034
response to mechanical stimulus	GO:0009612	134	0.033
negative regulation of apoptotic process	GO:0043066	181	0.033
positive regulation of cellular component organization	GO:0051130	200	0.033	Human Mouse
multi organism reproductive process	GO:0044703	262	0.033	Rat
regulation of nervous system development	GO:0051960	264	0.033	Mouse Fly
positive regulation of cellular biosynthetic process	GO:0031328	295	0.033
regulation of neuron death	GO:1901214	115	0.033
cellular response to endogenous stimulus	GO:0071495	377	0.033
response to transition metal nanoparticle	GO:1990267	122	0.032	Worm
growth	GO:0040007	165	0.032	Mouse Fly
developmental growth	GO:0048589	100	0.032	Mouse Fly
response to estrogen	GO:0043627	232	0.032
regulation of membrane potential	GO:0042391	110	0.032
chemical homeostasis	GO:0048878	292	0.032
central nervous system development	GO:0007417	311	0.031
carbohydrate metabolic process	GO:0005975	130	0.031
positive regulation of cellular protein metabolic process	GO:0032270	167	0.031
single organism biosynthetic process	GO:0044711	342	0.031
positive regulation of biosynthetic process	GO:0009891	319	0.031
transcription from rna polymerase ii promoter	GO:0006366	252	0.031
response to organophosphorus	GO:0046683	102	0.031
positive regulation of phosphorylation	GO:0042327	177	0.030
nucleobase containing small molecule metabolic process	GO:0055086	316	0.030
positive regulation of neuron projection development	GO:0010976	99	0.030	Mouse
cellular component movement	GO:0006928	248	0.030
negative regulation of macromolecule metabolic process	GO:0010605	260	0.030	Human
response to reactive oxygen species	GO:0000302	120	0.030
regeneration	GO:0031099	163	0.029
intracellular transport	GO:0046907	185	0.029
hormone secretion	GO:0046879	115	0.029
cellular response to peptide	GO:1901653	133	0.029
positive regulation of cell death	GO:0010942	184	0.028
action potential	GO:0001508	54	0.028
negative regulation of developmental process	GO:0051093	125	0.028
carboxylic acid metabolic process	GO:0019752	289	0.028
secretion by cell	GO:0032940	248	0.028
response to oxidative stress	GO:0006979	186	0.028
regulation of intracellular signal transduction	GO:1902531	218	0.028
cellular response to organonitrogen compound	GO:0071417	197	0.028
regulation of cellular amino acid metabolic process	GO:0006521	2	0.028
cellular response to acid chemical	GO:0071229	75	0.028
neuron development	GO:0048666	286	0.028	Mouse Fly
negative regulation of cell development	GO:0010721	82	0.027
positive regulation of protein modification process	GO:0031401	142	0.027
response to camp	GO:0051591	91	0.027
positive regulation of rna metabolic process	GO:0051254	203	0.027
positive regulation of transport	GO:0051050	245	0.027
regulation of tube size	GO:0035150	89	0.026
divalent inorganic cation homeostasis	GO:0072507	165	0.026
mapk cascade	GO:0000165	140	0.026
response to estradiol	GO:0032355	164	0.026
protein complex subunit organization	GO:0071822	302	0.025	Human Mouse
branched chain amino acid transport	GO:0015803	2	0.025
multicellular organismal reproductive process	GO:0048609	233	0.025	Rat
tissue development	GO:0009888	252	0.025	Fly
negative regulation of cellular metabolic process	GO:0031324	281	0.025	Human
regulation of organelle organization	GO:0033043	80	0.025	Human Mouse
neuron apoptotic process	GO:0051402	88	0.025
immune system process	GO:0002376	204	0.025
ion homeostasis	GO:0050801	212	0.025
actin filament based process	GO:0030029	86	0.024	Human Mouse Rat Fly
response to metal ion	GO:0010038	253	0.024	Worm
positive regulation of apoptotic process	GO:0043065	154	0.024
positive regulation of cell projection organization	GO:0031346	111	0.024	Mouse
cellular cation homeostasis	GO:0030003	180	0.024
secretion	GO:0046903	307	0.024
regulation of cellular component biogenesis	GO:0044087	86	0.024	Human Mouse
alpha amino acid metabolic process	GO:1901605	71	0.024
aging	GO:0007568	241	0.023	Worm
single organism reproductive process	GO:0044702	297	0.023	Rat
positive regulation of phosphate metabolic process	GO:0045937	262	0.023
regulation of hormone secretion	GO:0046883	106	0.023
cation transport	GO:0006812	382	0.023
carbohydrate derivative metabolic process	GO:1901135	346	0.023
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.023
positive regulation of rna biosynthetic process	GO:1902680	197	0.023
cell cell signaling	GO:0007267	335	0.023
sensory perception	GO:0007600	101	0.023
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.023
single organism carbohydrate metabolic process	GO:0044723	118	0.023
response to external biotic stimulus	GO:0043207	221	0.022	Zebrafish
organonitrogen compound catabolic process	GO:1901565	179	0.022
positive regulation of kinase activity	GO:0033674	77	0.022
regulation of blood circulation	GO:1903522	110	0.022
cellular ion homeostasis	GO:0006873	184	0.022
positive regulation of gene expression	GO:0010628	244	0.022
cellular component morphogenesis	GO:0032989	155	0.022	Mouse Fly
heart contraction	GO:0060047	57	0.022
negative regulation of programmed cell death	GO:0043069	183	0.022
eye morphogenesis	GO:0048592	4	0.022
regulation of rna metabolic process	GO:0051252	391	0.022
response to ketone	GO:1901654	182	0.022
cellular macromolecule localization	GO:0070727	122	0.022
cell type specific apoptotic process	GO:0097285	134	0.022
macromolecule localization	GO:0033036	252	0.022
establishment of protein localization	GO:0045184	141	0.021
negative regulation of response to stimulus	GO:0048585	155	0.021
regulation of cellular ketone metabolic process	GO:0010565	27	0.021
negative regulation of signal transduction	GO:0009968	83	0.021
regulation of epithelial cell proliferation	GO:0050678	49	0.021
aromatic compound catabolic process	GO:0019439	168	0.021
organonitrogen compound biosynthetic process	GO:1901566	167	0.021
positive regulation of protein kinase activity	GO:0045860	73	0.021
urogenital system development	GO:0001655	78	0.021
synaptic growth at neuromuscular junction	GO:0051124	1	0.020	Fly
response to corticosteroid	GO:0031960	235	0.020
purine containing compound metabolic process	GO:0072521	253	0.020
protein transport	GO:0015031	132	0.020
peptide secretion	GO:0002790	86	0.020
response to axon injury	GO:0048678	59	0.020
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	41	0.020	Mouse
endocytosis	GO:0006897	84	0.020
response to insulin	GO:0032868	133	0.020
organophosphate metabolic process	GO:0019637	370	0.019
cell growth	GO:0016049	104	0.019	Mouse
response to toxic substance	GO:0009636	133	0.019
reproductive system development	GO:0061458	128	0.019
negative regulation of neurogenesis	GO:0050768	78	0.019
cytosolic calcium ion homeostasis	GO:0051480	140	0.019
positive regulation of intracellular signal transduction	GO:1902533	138	0.019
negative regulation of cell differentiation	GO:0045596	99	0.019
lipid metabolic process	GO:0006629	283	0.019
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.019	Mouse Fly
embryonic pattern specification	GO:0009880	1	0.019
positive regulation of protein serine threonine kinase activity	GO:0071902	52	0.018
positive regulation of cellular amine metabolic process	GO:0033240	3	0.018
regulation of protein kinase activity	GO:0045859	105	0.018
regulation of axonogenesis	GO:0050770	37	0.018	Mouse Fly
single organism intracellular transport	GO:1902582	166	0.018
vesicle mediated transport	GO:0016192	181	0.018
signal transduction by phosphorylation	GO:0023014	144	0.018
organic hydroxy compound metabolic process	GO:1901615	115	0.018
motor neuron axon guidance	GO:0008045	1	0.018
purine nucleotide metabolic process	GO:0006163	229	0.018
negative regulation of cell death	GO:0060548	229	0.018
forebrain development	GO:0030900	98	0.018
signal release	GO:0023061	145	0.018
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.018
kidney development	GO:0001822	67	0.018
positive regulation of programmed cell death	GO:0043068	157	0.018
embryonic axis specification	GO:0000578	1	0.018
regulation of mrna splicing via spliceosome	GO:0048024	3	0.018
transmembrane transport	GO:0055085	412	0.018
regulation of blood vessel size	GO:0050880	89	0.017
regulation of protein metabolic process	GO:0051246	289	0.017	Human
epithelium development	GO:0060429	96	0.017	Fly
dephosphorylation	GO:0016311	98	0.017
positive regulation of transferase activity	GO:0051347	81	0.017
actin cytoskeleton organization	GO:0030036	73	0.017	Human Mouse Rat Fly
ras protein signal transduction	GO:0007265	29	0.017
response to growth factor	GO:0070848	189	0.017
sensory perception of pain	GO:0019233	73	0.017
positive regulation of peptide secretion	GO:0002793	52	0.017
regulation of cytoskeleton organization	GO:0051493	49	0.017	Human Mouse
reproductive structure development	GO:0048608	128	0.017
response to cocaine	GO:0042220	39	0.016
peptide transport	GO:0015833	97	0.016
regulation of cell motility	GO:2000145	131	0.016
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.016
positive regulation of secretion	GO:0051047	140	0.016
cell morphogenesis	GO:0000902	142	0.016	Mouse Fly
cellular lipid metabolic process	GO:0044255	208	0.016
peptide hormone secretion	GO:0030072	84	0.016
hexose metabolic process	GO:0019318	58	0.016
cell projection morphogenesis	GO:0048858	123	0.016	Mouse Fly
regulation of system process	GO:0044057	208	0.016
cellular response to nitrogen compound	GO:1901699	210	0.016
negative regulation of cellular component organization	GO:0051129	83	0.016
circulatory system development	GO:0072359	134	0.016
axis specification	GO:0009798	4	0.016
heart morphogenesis	GO:0003007	3	0.016
metal ion homeostasis	GO:0055065	186	0.016
reproduction	GO:0000003	245	0.016	Rat
positive regulation of smooth muscle cell proliferation	GO:0048661	51	0.016
small molecule biosynthetic process	GO:0044283	124	0.016
glycosyl compound metabolic process	GO:1901657	182	0.016
membrane organization	GO:0061024	94	0.015
protein oligomerization	GO:0051259	191	0.015
regulation of immune system process	GO:0002682	123	0.015
cellular protein complex assembly	GO:0043623	44	0.015
heterocycle catabolic process	GO:0046700	167	0.015
synaptic transmission	GO:0007268	235	0.015
cellular response to lipid	GO:0071396	201	0.015
small gtpase mediated signal transduction	GO:0007264	36	0.015
cellular ketone metabolic process	GO:0042180	51	0.015
negative regulation of cellular protein metabolic process	GO:0032269	106	0.015	Human
cellular response to peptide hormone stimulus	GO:0071375	120	0.015
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.015
cellular response to growth factor stimulus	GO:0071363	162	0.015
regulation of hormone levels	GO:0010817	187	0.015
organophosphate catabolic process	GO:0046434	148	0.015
regulation of secretion by cell	GO:1903530	208	0.015
regulation of behavior	GO:0050795	61	0.015
neuron projection morphogenesis	GO:0048812	122	0.015	Mouse Fly
nucleoside metabolic process	GO:0009116	179	0.015
telencephalon development	GO:0021537	62	0.015
regulation of small gtpase mediated signal transduction	GO:0051056	48	0.015
hormone transport	GO:0009914	121	0.015
camera type eye morphogenesis	GO:0048593	2	0.014
response to purine containing compound	GO:0014074	126	0.014
positive regulation of hormone secretion	GO:0046887	65	0.014
male mating behavior	GO:0060179	3	0.014
negative regulation of nervous system development	GO:0051961	79	0.014
sensory organ development	GO:0007423	74	0.014	Fly
regulation of synaptic transmission	GO:0050804	141	0.014
multi multicellular organism process	GO:0044706	138	0.014
single organism behavior	GO:0044708	130	0.014
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.014
lymphocyte activation	GO:0046649	43	0.014
cell morphogenesis involved in differentiation	GO:0000904	119	0.014	Mouse Fly
positive regulation of cellular component movement	GO:0051272	102	0.014
regulation of response to external stimulus	GO:0032101	106	0.014
cellular response to oxidative stress	GO:0034599	76	0.014
cell adhesion	GO:0007155	110	0.014	Rat
negative regulation of molecular function	GO:0044092	133	0.014	Human
nucleoside phosphate metabolic process	GO:0006753	283	0.014
positive regulation of transcription dna templated	GO:0045893	197	0.014
regulation of heart contraction	GO:0008016	48	0.013
cardiac chamber development	GO:0003205	1	0.013
regulation of organic acid transport	GO:0032890	35	0.013
response to other organism	GO:0051707	220	0.013	Zebrafish
neuron neuron synaptic transmission	GO:0007270	60	0.013
regulation of dna metabolic process	GO:0051052	60	0.013
response to hydrogen peroxide	GO:0042542	89	0.013
axonogenesis	GO:0007409	71	0.013	Mouse Fly
sexual reproduction	GO:0019953	148	0.013	Rat
axon regeneration	GO:0031103	28	0.013
adult locomotory behavior	GO:0008344	4	0.013
response to vitamin	GO:0033273	131	0.013
regulation of potassium ion transport	GO:0043266	29	0.013
behavior	GO:0007610	205	0.013
regulation of synaptic plasticity	GO:0048167	70	0.013
monovalent inorganic cation transport	GO:0015672	172	0.013
regulation of transferase activity	GO:0051338	123	0.013	Human
purine nucleoside metabolic process	GO:0042278	169	0.013
neuronal action potential	GO:0019228	35	0.013
renal system development	GO:0072001	67	0.013
negative regulation of cellular biosynthetic process	GO:0031327	161	0.013
cell activation	GO:0001775	97	0.013
reactive oxygen species metabolic process	GO:0072593	37	0.012
retina morphogenesis in camera type eye	GO:0060042	1	0.012
chromosome segregation	GO:0007059	2	0.012
schwann cell migration	GO:0036135	2	0.012
regulation of kinase activity	GO:0043549	117	0.012
organ morphogenesis	GO:0009887	75	0.012	Fly
cofactor metabolic process	GO:0051186	95	0.012
positive regulation of nucleotide metabolic process	GO:0045981	91	0.012
response to alkaloid	GO:0043279	132	0.012
positive regulation of somatostatin secretion	GO:0090274	4	0.012
leukocyte activation	GO:0045321	76	0.012
regulation of smooth muscle cell migration	GO:0014910	36	0.012
positive regulation of secretion by cell	GO:1903532	128	0.012
regulation of defecation	GO:2000292	1	0.012
locomotory exploration behavior	GO:0035641	1	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.012
proteolysis	GO:0006508	175	0.012
response to hexose	GO:0009746	144	0.012
response to carbohydrate	GO:0009743	183	0.012
negative regulation of gene expression	GO:0010629	199	0.012
response to zinc ion	GO:0010043	39	0.012
gliogenesis	GO:0042063	93	0.012
regulation of peptide hormone secretion	GO:0090276	80	0.012
regulation of catabolic process	GO:0009894	113	0.012
negative regulation of transport	GO:0051051	136	0.012
organic cyclic compound catabolic process	GO:1901361	175	0.012
negative regulation of neuron differentiation	GO:0045665	62	0.011
cognition	GO:0050890	92	0.011
positive regulation of inflammatory response	GO:0050729	24	0.011
developmental growth involved in morphogenesis	GO:0060560	33	0.011	Mouse
purine ribonucleoside catabolic process	GO:0046130	124	0.011
negative regulation of phosphate metabolic process	GO:0045936	80	0.011
cell communication involved in cardiac conduction	GO:0086065	2	0.011
osteoblast differentiation	GO:0001649	26	0.011
mitotic spindle organization	GO:0007052	2	0.011
cellular nitrogen compound catabolic process	GO:0044270	163	0.011
regulation of mapk cascade	GO:0043408	116	0.011
ribose phosphate metabolic process	GO:0019693	235	0.011
negative regulation of protein metabolic process	GO:0051248	114	0.011	Human
positive regulation of hydrolase activity	GO:0051345	86	0.011
regulation of endothelial cell apoptotic process	GO:2000351	3	0.011
actin crosslink formation	GO:0051764	3	0.011
b cell differentiation	GO:0030183	2	0.011
response to ammonium ion	GO:0060359	71	0.011
regulation of hydrolase activity	GO:0051336	143	0.011
ion transmembrane transport	GO:0034220	365	0.011
nucleotide catabolic process	GO:0009166	139	0.011
response to radiation	GO:0009314	137	0.011
epithelial cell differentiation	GO:0030855	71	0.011	Fly
cardiovascular system development	GO:0072358	134	0.011
response to increased oxygen levels	GO:0036296	45	0.011
cellular response to insulin stimulus	GO:0032869	81	0.011
gastrulation	GO:0007369	2	0.011
neurotransmitter gated ion channel clustering	GO:0072578	3	0.011
gamete generation	GO:0007276	124	0.011	Rat
regulation of cell morphogenesis	GO:0022604	77	0.011	Mouse Fly
response to hyperoxia	GO:0055093	45	0.011
purine ribonucleoside metabolic process	GO:0046128	168	0.010
metanephric s shaped body morphogenesis	GO:0072284	2	0.010
spindle organization	GO:0007051	2	0.010
regulation of vasculature development	GO:1901342	44	0.010
response to temperature stimulus	GO:0009266	94	0.010
smooth muscle cell proliferation	GO:0048659	77	0.010
response to electrical stimulus	GO:0051602	56	0.010
negative regulation of protein phosphorylation	GO:0001933	44	0.010
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.010
response to cytokine	GO:0034097	215	0.010
transmission of nerve impulse	GO:0019226	42	0.010
nucleotide metabolic process	GO:0009117	279	0.010
regulation of protein localization	GO:0032880	81	0.010
response to activity	GO:0014823	73	0.010
prepulse inhibition	GO:0060134	1	0.010
alternative mrna splicing via spliceosome	GO:0000380	4	0.010
cellular response to external stimulus	GO:0071496	118	0.010
dna metabolic process	GO:0006259	96	0.010
sex differentiation	GO:0007548	113	0.010

Limk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.012
nervous system disease	DOID:863	0.012
central nervous system disease	DOID:331	0.012

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