Rattus norvegicus

62 known processes

Pdgfa

platelet-derived growth factor alpha polypeptide

(Aliases: PDGFACP)

Pdgfa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of signal transductionGO:00099663180.238
cell projection organizationGO:00300303020.185
regulation of cellular component movementGO:00512701500.171
cellular component morphogenesisGO:00329891550.170
regulation of transcription dna templatedGO:00063553740.169
cellular component movementGO:00069282480.163
negative regulation of cellular metabolic processGO:00313242810.161
negative regulation of biosynthetic processGO:00098901680.157
anatomical structure morphogenesisGO:00096532980.152
regulation of secretionGO:00510462240.150
rna biosynthetic processGO:00327743800.147
transcription dna templatedGO:00063513770.144
nucleic acid templated transcriptionGO:00976593790.139
regulation of intracellular signal transductionGO:19025312180.132
regulation of nucleic acid templated transcriptionGO:19035063800.132
positive regulation of developmental processGO:00510942830.131
positive regulation of programmed cell deathGO:00430681570.128
transcription from rna polymerase ii promoterGO:00063662520.123
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.119
regulation of multicellular organismal developmentGO:20000263760.119
negative regulation of macromolecule biosynthetic processGO:00105581480.119
cell motilityGO:00488702020.116
neuron developmentGO:00486662860.112
negative regulation of rna biosynthetic processGO:19026791180.112
intracellular signal transductionGO:00355563140.111
rna metabolic processGO:00160704060.109
macromolecule localizationGO:00330362520.105
response to growth factorGO:00708481890.104
cellular component biogenesisGO:00440853680.101
negative regulation of nucleobase containing compound metabolic processGO:00459341530.100
cellular component assemblyGO:00226073600.099
neuron differentiationGO:00301823680.098
negative regulation of macromolecule metabolic processGO:00106052600.097
regulation of cellular localizationGO:00603412630.095
negative regulation of rna metabolic processGO:00512531230.093
neuron projection developmentGO:00311752730.092
regulation of cell differentiationGO:00455953200.092
cell morphogenesisGO:00009021420.090
regulation of rna biosynthetic processGO:20011413810.089
negative regulation of nitrogen compound metabolic processGO:00511721610.088
secretionGO:00469033070.087
regulation of cellular component organizationGO:00511283680.084
regulation of cell developmentGO:00602842630.083
locomotionGO:00400112370.082
apoptotic processGO:00069153810.082
positive regulation of cell differentiationGO:00455972170.081
protein localizationGO:00081041910.076
negative regulation of nucleic acid templated transcriptionGO:19035071170.076
metal ion transportGO:00300012890.076
circulatory system developmentGO:00723591340.075
protein complex biogenesisGO:00702712630.074
positive regulation of rna biosynthetic processGO:19026801970.074
regulation of rna metabolic processGO:00512523910.073
regulation of transcription from rna polymerase ii promoterGO:00063572340.072
regulation of phosphate metabolic processGO:00192203490.071
immune system processGO:00023762040.071
positive regulation of response to stimulusGO:00485842850.070
macromolecular complex subunit organizationGO:00439333390.070
protein complex assemblyGO:00064612630.069
regulation of locomotionGO:00400121480.069
positive regulation of cell communicationGO:00106472710.068
negative regulation of metabolic processGO:00098923310.068
localization of cellGO:00516742020.068
positive regulation of apoptotic processGO:00430651540.068
negative regulation of response to stimulusGO:00485851550.066
nitrogen compound transportGO:00717052290.065
negative regulation of cell proliferationGO:00082851190.065
positive regulation of nucleic acid templated transcriptionGO:19035081970.064
regulation of protein metabolic processGO:00512462890.064
negative regulation of gene expressionGO:00106291990.062
cation transportGO:00068123820.062
regulation of nervous system developmentGO:00519602640.062
secretion by cellGO:00329402480.061
regulation of secretion by cellGO:19035302080.061
g protein coupled receptor signaling pathwayGO:00071862420.060
positive regulation of phosphorus metabolic processGO:00105622620.060
regulation of apoptotic processGO:00429813350.059
single organism reproductive processGO:00447022970.058
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.057
negative regulation of transcription dna templatedGO:00458921160.057
cell migrationGO:00164771970.057
cell part morphogenesisGO:00329901230.057
positive regulation of multicellular organismal processGO:00512403870.056
positive regulation of nitrogen compound metabolic processGO:00511733340.056
response to oxygen levelsGO:00704822650.056
positive regulation of macromolecule biosynthetic processGO:00105572470.056
positive regulation of nervous system developmentGO:00519621780.056
regulation of cell proliferationGO:00421273590.056
regulation of phosphorus metabolic processGO:00511743490.055
positive regulation of cell deathGO:00109421840.054
response to hypoxiaGO:00016662310.053
cardiovascular system developmentGO:00723581340.053
organelle organizationGO:00069962660.053
regulation of neuron differentiationGO:00456642080.051
positive regulation of biosynthetic processGO:00098913190.051
tissue developmentGO:00098882520.051
negative regulation of cellular biosynthetic processGO:00313271610.051
regulation of neurogenesisGO:00507672470.050
reproductionGO:00000032450.050
positive regulation of cellular component movementGO:00512721020.050
developmental growthGO:00485891000.050
positive regulation of gene expressionGO:00106282440.049
positive regulation of cell migrationGO:0030335960.049
positive regulation of nucleobase containing compound metabolic processGO:00459353190.049
positive regulation of molecular functionGO:00440932300.049
cellular response to stressGO:00335542690.049
response to decreased oxygen levelsGO:00362932370.048
cell cell signalingGO:00072673350.048
response to external biotic stimulusGO:00432072210.048
single organism organelle organizationGO:19025891800.048
regulation of cell morphogenesis involved in differentiationGO:0010769720.048
negative regulation of cell communicationGO:00106481580.048
positive regulation of signal transductionGO:00099671750.048
regulation of molecular functionGO:00650093980.048
cellular response to oxygen containing compoundGO:19017013860.048
cellular homeostasisGO:00197252520.048
bmp signaling pathwayGO:003050940.048
regulation of programmed cell deathGO:00430673410.047
regulation of cell motilityGO:20001451310.047
gland developmentGO:00487321550.047
positive regulation of signalingGO:00230562700.047
positive regulation of rna metabolic processGO:00512542030.046
response to other organismGO:00517072200.046
homeostatic processGO:00425923310.045
regulation of cell migrationGO:00303341280.044
negative regulation of multicellular organismal processGO:00512412030.044
positive regulation of cell proliferationGO:00082842490.043
negative regulation of signalingGO:00230571570.043
positive regulation of cellular component organizationGO:00511302000.043
programmed cell deathGO:00125013920.043
response to glucocorticoidGO:00513842230.042
macromolecular complex assemblyGO:00650032730.042
protein phosphorylationGO:00064683450.041
response to biotic stimulusGO:00096072260.041
behaviorGO:00076102050.041
response to extracellular stimulusGO:00099913800.041
regenerationGO:00310991630.041
reproductive processGO:00224143720.040
regulation of catalytic activityGO:00507903040.040
positive regulation of neurogenesisGO:00507691650.040
response to woundingGO:00096112540.040
mesoderm developmentGO:000749820.039
response to estradiolGO:00323551640.038
agingGO:00075682410.038
carbohydrate derivative metabolic processGO:19011353460.038
positive regulation of transcription dna templatedGO:00458931970.038
single organism biosynthetic processGO:00447113420.038
chemical homeostasisGO:00488782920.038
carboxylic acid transportGO:00469421150.038
multicellular organism reproductionGO:00325042330.037
regulation of system processGO:00440572080.037
hepaticobiliary system developmentGO:0061008900.037
cellular ion homeostasisGO:00068731840.037
response to bacteriumGO:00096172000.037
positive regulation of phosphorylationGO:00423271770.036
nucleotide metabolic processGO:00091172790.036
biological adhesionGO:00226101100.036
metal ion homeostasisGO:00550651860.036
regulation of ion transportGO:00432692450.036
response to corticosteroidGO:00319602350.036
cellular response to organic cyclic compoundGO:00714072020.036
cell projection morphogenesisGO:00488581230.036
regulation of ossificationGO:0030278320.036
ion homeostasisGO:00508012120.036
neuron projection morphogenesisGO:00488121220.036
cell morphogenesis involved in differentiationGO:00009041190.036
anatomical structure formation involved in morphogenesisGO:0048646830.035
catabolic processGO:00090563510.035
multicellular organismal reproductive processGO:00486092330.035
brain developmentGO:00074202470.035
response to inorganic substanceGO:00100353770.034
multi organism reproductive processGO:00447032620.034
positive regulation of transportGO:00510502450.034
regulation of response to stressGO:00801341260.034
proteolysisGO:00065081750.034
regulation of neuron projection developmentGO:00109751610.034
cellular response to growth factor stimulusGO:00713631620.034
regulation of proteasomal protein catabolic processGO:006113640.034
cellular response to endogenous stimulusGO:00714953770.034
cell morphogenesis involved in neuron differentiationGO:00486671060.033
transmembrane transportGO:00550854120.033
positive regulation of cell projection organizationGO:00313461110.033
synaptic growth at neuromuscular junctionGO:005112410.032
gastrulationGO:000736920.032
regulation of cellular amino acid metabolic processGO:000652120.032
cellular macromolecule localizationGO:00707271220.032
central nervous system developmentGO:00074173110.032
cellular catabolic processGO:00442482950.032
establishment of protein localizationGO:00451841410.032
reproductive system developmentGO:00614581280.032
response to cytokineGO:00340972150.032
positive regulation of cell motilityGO:2000147970.031
organic substance catabolic processGO:19015753160.031
cation transmembrane transportGO:00986552630.031
cell adhesionGO:00071551100.031
negative regulation of signal transductionGO:0009968830.031
oxoacid metabolic processGO:00434362900.031
positive regulation of cellular biosynthetic processGO:00313282950.031
organonitrogen compound biosynthetic processGO:19015661670.031
cellular amine metabolic processGO:0044106380.031
divalent inorganic cation homeostasisGO:00725071650.031
cellular response to nitrogen compoundGO:19016992100.030
regulation of chemotaxisGO:0050920290.030
signal transduction by phosphorylationGO:00230141440.030
divalent inorganic cation transportGO:00725111340.030
membrane organizationGO:0061024940.030
cell fate determinationGO:000170920.030
reproductive structure developmentGO:00486081280.030
forebrain developmentGO:0030900980.030
cardiac chamber developmentGO:000320510.030
epithelium developmentGO:0060429960.029
organ regenerationGO:00311001010.029
protein complex subunit organizationGO:00718223020.029
wound healingGO:00420601220.029
amine metabolic processGO:0009308380.029
intracellular transportGO:00469071850.028
response to ketoneGO:19016541820.028
cellular amino acid metabolic processGO:00065201070.028
activation of cysteine type endopeptidase activityGO:009720240.028
ossificationGO:0001503700.028
response to nutrient levelsGO:00316673700.028
regulation of cellular ketone metabolic processGO:0010565270.028
organophosphate metabolic processGO:00196373700.028
positive regulation of protein metabolic processGO:00512471780.028
cellular protein localizationGO:00346131220.028
regulation of anatomical structure sizeGO:00900661350.028
protein oligomerizationGO:00512591910.027
cation homeostasisGO:00550801950.027
positive regulation of catalytic activityGO:00430851840.027
gonad developmentGO:00084061040.027
positive regulation of locomotionGO:00400171020.027
cellular chemical homeostasisGO:00550822470.027
heart developmentGO:0007507720.027
chemotaxisGO:0006935660.027
sex differentiationGO:00075481130.027
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.027
regulation of phosphorylationGO:00423252480.027
regulation of protein localizationGO:0032880810.026
regulation of kinase activityGO:00435491170.026
regulation of transferase activityGO:00513381230.026
organic acid metabolic processGO:00060822920.026
regulation of protein modification processGO:00313991940.026
immune responseGO:00069551040.026
mapk cascadeGO:00001651400.026
response to lipopolysaccharideGO:00324961910.026
tube developmentGO:0035295890.026
defense responseGO:00069521940.026
digestive tract developmentGO:0048565390.025
positive regulation of intracellular signal transductionGO:19025331380.025
purine ribonucleotide metabolic processGO:00091502270.025
positive regulation of secretion by cellGO:19035321280.025
enzyme linked receptor protein signaling pathwayGO:00071671160.025
regulation of hydrolase activityGO:00513361430.025
positive regulation of secretionGO:00510471400.025
cellular response to organonitrogen compoundGO:00714171970.025
positive regulation of phosphate metabolic processGO:00459372620.025
regulation of cellular amine metabolic processGO:003323880.024
single organism intracellular transportGO:19025821660.024
regulation of cellular catabolic processGO:00313291010.024
protein heterooligomerizationGO:0051291890.024
ribose phosphate metabolic processGO:00196932350.024
negative regulation of developmental processGO:00510931250.023
regulation of cellular protein metabolic processGO:00322682670.023
ribonucleotide metabolic processGO:00092592310.023
positive regulation of transferase activityGO:0051347810.023
regulation of fat cell differentiationGO:004559830.023
heart morphogenesisGO:000300730.023
negative regulation of molecular functionGO:00440921330.023
response to monosaccharideGO:00342841590.023
negative regulation of transportGO:00510511360.023
regulation of protein kinase activityGO:00458591050.023
cellular cation homeostasisGO:00300031800.023
response to peptide hormoneGO:00434342780.023
positive regulation of cell developmentGO:00107201760.023
divalent metal ion transportGO:00708381320.023
regulation of anatomical structure morphogenesisGO:00226031410.023
ras protein signal transductionGO:0007265290.023
heterocycle catabolic processGO:00467001670.023
cellular response to hormone stimulusGO:00328702470.023
regulation of protein phosphorylationGO:00019321830.023
positive regulation of kinase activityGO:0033674770.023
anterior posterior pattern specificationGO:000995210.022
kidney developmentGO:0001822670.022
small gtpase mediated signal transductionGO:0007264360.022
epithelial cell differentiationGO:0030855710.022
response to temperature stimulusGO:0009266940.022
synaptic transmissionGO:00072682350.022
cellular response to lipidGO:00713962010.022
anion transportGO:00068201780.022
response to peptideGO:19016522920.022
head developmentGO:00603222470.022
regulation of mapk cascadeGO:00434081160.022
response to radiationGO:00093141370.022
ion transmembrane transportGO:00342203650.022
amide transportGO:00428861050.022
purine nucleotide metabolic processGO:00061632290.022
negative regulation of cell developmentGO:0010721820.021
regulation of immune system processGO:00026821230.021
negative regulation of programmed cell deathGO:00430691830.021
response to molecule of bacterial originGO:00022371940.021
liver developmentGO:0001889900.021
negative regulation of phosphorus metabolic processGO:0010563800.021
response to acid chemicalGO:00011012220.021
cellular ketone metabolic processGO:0042180510.021
negative regulation of cell deathGO:00605482290.021
epithelial cell proliferationGO:0050673540.021
cellular nitrogen compound catabolic processGO:00442701630.021
vascular process in circulatory systemGO:0003018960.021
single organism membrane organizationGO:0044802740.021
positive regulation of hydrolase activityGO:0051345860.021
regulation of cell projection organizationGO:00313441750.021
calcium ion transportGO:00068161310.020
renal system developmentGO:0072001670.020
nucleoside phosphate metabolic processGO:00067532830.020
single organism cellular localizationGO:19025801020.020
exocytosisGO:0006887600.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
positive regulation of cellular amine metabolic processGO:003324030.020
cellular lipid metabolic processGO:00442552080.020
axon developmentGO:0061564960.020
response to insulinGO:00328681330.019
urogenital system developmentGO:0001655780.019
salivary gland developmentGO:000743130.019
carboxylic acid metabolic processGO:00197522890.019
sexual reproductionGO:00199531480.019
cytoplasmic transportGO:00164821150.019
erk1 and erk2 cascadeGO:0070371480.019
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.019
organ morphogenesisGO:0009887750.019
rhythmic processGO:00485111560.019
regulation of establishment of protein localizationGO:0070201690.019
inflammatory responseGO:00069541500.019
regulation of behaviorGO:0050795610.019
negative regulation of apoptotic processGO:00430661810.019
negative regulation of cell differentiationGO:0045596990.019
oxidation reduction processGO:00551143040.018
cytoskeleton organizationGO:00070101110.018
peptide transportGO:0015833970.018
muscle structure developmentGO:0061061870.018
organophosphate catabolic processGO:00464341480.018
purine ribonucleoside metabolic processGO:00461281680.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
positive regulation of neuron differentiationGO:00456661260.018
mechanoreceptor differentiationGO:004249020.018
development of primary sexual characteristicsGO:00451371070.018
cell type specific apoptotic processGO:00972851340.018
growthGO:00400071650.018
organonitrogen compound catabolic processGO:19015651790.018
cellular metal ion homeostasisGO:00068751720.018
nucleobase containing small molecule metabolic processGO:00550863160.018
inorganic ion transmembrane transportGO:00986602290.017
regulation of nucleotide metabolic processGO:00061401170.017
vasculature developmentGO:0001944700.017
cellular calcium ion homeostasisGO:00068741600.017
purine nucleoside catabolic processGO:00061521240.017
regulation of peptide transportGO:0090087870.017
cytosolic calcium ion homeostasisGO:00514801400.017
response to hydrogen peroxideGO:0042542890.017
regulation of protein transportGO:0051223680.017
dephosphorylationGO:0016311980.017
taxisGO:0042330670.017
regulation of growthGO:00400081050.017
regulation of cytokine productionGO:0001817560.017
neurological system processGO:00508772190.017
negative regulation of protein metabolic processGO:00512481140.017
regulation of cellular component biogenesisGO:0044087860.017
negative regulation of phosphate metabolic processGO:0045936800.017
purine nucleoside triphosphate metabolic processGO:00091441410.017
formation of primary germ layerGO:000170410.017
cell differentiation involved in kidney developmentGO:006100540.017
small molecule biosynthetic processGO:00442831240.017
regulation of hormone levelsGO:00108171870.017
sensory perceptionGO:00076001010.017
axonogenesisGO:0007409710.016
mesenchymal cell proliferationGO:001046340.016
nucleoside triphosphate metabolic processGO:00091411440.016
axis specificationGO:000979840.016
tube formationGO:003514830.016
regulation of canonical wnt signaling pathwayGO:006082840.016
calcium ion homeostasisGO:00550741620.016
actin filament based processGO:0030029860.016
regulation of catabolic processGO:00098941130.016
positive regulation of protein kinase activityGO:0045860730.016
response to carbohydrateGO:00097431830.016
regulation of organelle organizationGO:0033043800.016
muscle tissue developmentGO:0060537580.016
regulation of epithelial cell proliferationGO:0050678490.016
embryo developmentGO:0009790490.016
vesicle mediated transportGO:00161921810.016
female gonad developmentGO:0008585530.016
positive regulation of cytosolic calcium ion concentrationGO:00072041220.016
carbohydrate derivative catabolic processGO:19011361470.016
regulation of osteoblast differentiationGO:0045667140.015
respiratory system developmentGO:0060541450.015
osteoblast differentiationGO:0001649260.015
purine nucleotide catabolic processGO:00061951360.015
regulation of stem cell proliferationGO:0072091140.015
positive regulation of protein modification processGO:00314011420.015
response to oxidative stressGO:00069791860.015
circulatory system processGO:00030131830.015
lipid metabolic processGO:00066292830.015
positive regulation of immune system processGO:0002684900.015
glycosyl compound catabolic processGO:19016581260.015
rho protein signal transductionGO:0007266110.015
negative regulation of secretionGO:0051048820.015
regulation of protein serine threonine kinase activityGO:0071900640.015
endomembrane system organizationGO:0010256480.015
single organism catabolic processGO:00447122830.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.015
response to glucoseGO:00097491360.015
organic cyclic compound catabolic processGO:19013611750.015
response to estrogenGO:00436272320.015
response to alkaloidGO:00432791320.015
response to hexoseGO:00097461440.015
embryonic appendage morphogenesisGO:003511340.015
regulation of response to external stimulusGO:00321011060.015
response to transforming growth factor betaGO:0071559460.015
positive regulation of neuron projection developmentGO:0010976990.015
regulation of hormone secretionGO:00468831060.015
dna metabolic processGO:0006259960.015
lipid biosynthetic processGO:00086101280.015
ribonucleoside catabolic processGO:00424541260.015
response to metal ionGO:00100382530.015
regulation of blood vessel sizeGO:0050880890.015
regulation of metal ion transportGO:00109591180.015
organic acid transportGO:00158491160.015
negative regulation of catalytic activityGO:00430861030.015
cell substrate adhesionGO:0031589290.014
protein transportGO:00150311320.014
regulation of calcium ion transportGO:0051924770.014
multicellular organismal signalingGO:0035637440.014
cardiac ventricle developmentGO:000323110.014
embryonic pattern specificationGO:000988010.014
positive regulation of cellular component biogenesisGO:0044089550.014
gliogenesisGO:0042063930.014
cellular response to corticosteroid stimulusGO:0071384690.014
cellular response to cytokine stimulusGO:00713451270.014
regulation of purine nucleotide metabolic processGO:19005421150.014
response to reactive oxygen speciesGO:00003021200.014
smooth muscle cell proliferationGO:0048659770.014
negative regulation of secretion by cellGO:1903531720.014
nucleoside metabolic processGO:00091161790.014
muscle system processGO:00030121150.014
positive regulation of mapk cascadeGO:0043410920.014
cyclic nucleotide metabolic processGO:0009187800.014
developmental process involved in reproductionGO:00030061590.014
purine containing compound metabolic processGO:00725212530.014
positive regulation of protein phosphorylationGO:00019341350.014
cellular response to steroid hormone stimulusGO:0071383930.014
positive regulation of hepatocyte differentiationGO:007036820.014
muscle cell proliferationGO:0033002840.014
coronary vasculature morphogenesisGO:006097730.014
nucleotide catabolic processGO:00091661390.014
hematopoietic progenitor cell differentiationGO:000224420.013
regulation of cell morphogenesisGO:0022604770.013
nucleoside phosphate catabolic processGO:19012921400.013
single organism behaviorGO:00447081300.013
regulation of membrane potentialGO:00423911100.013
regulation of dna metabolic processGO:0051052600.013
gtp metabolic processGO:0046039720.013
positive regulation of ion transportGO:0043270940.013
spermatogenesisGO:0007283990.013
regulation of organ formationGO:000315620.013
gtp catabolic processGO:0006184710.013
regulation of proteolysisGO:0030162660.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.013
camera type eye developmentGO:0043010480.013
cognitionGO:0050890920.013
negative regulation of intracellular signal transductionGO:1902532380.013
purine ribonucleotide catabolic processGO:00091541360.013
eye morphogenesisGO:004859240.013
cell cell junction organizationGO:0045216200.013
regulation of homeostatic processGO:00328441010.013
amino acid transportGO:0006865700.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
regulation of purine nucleotide catabolic processGO:0033121650.012
ribonucleoside metabolic processGO:00091191740.012
ovulation cycleGO:0042698670.012
purine nucleoside metabolic processGO:00422781690.012
neuron deathGO:00709971270.012
response to vitaminGO:00332731310.012
inner ear receptor cell differentiationGO:006011320.012
sensory perception of painGO:0019233730.012
synapse organizationGO:0050808460.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.012
neuronal action potentialGO:0019228350.012
regulation of cellular response to stressGO:0080135490.012
asymmetric protein localizationGO:000810520.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.012
organ formationGO:004864530.012
regulation of map kinase activityGO:0043405530.012

Pdgfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
urinary system diseaseDOID:1800.025
sensory system diseaseDOID:005015500.017
musculoskeletal system diseaseDOID:1700.014