IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Yars

tyrosyl-tRNA synthetase

(Aliases: MGC112837)

Entrez: 313047
RGD: 1307616
Ensembl: ENSRNOG00000007213
UniProtKB: Q4KM49

Process Predictions
Disease Predictions

Yars biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
trna aminoacylation	GO:0043039	3	0.929
amino acid activation	GO:0043038	3	0.922
trna aminoacylation for protein translation	GO:0006418	3	0.917
trna metabolic process	GO:0006399	4	0.447
cellular amino acid metabolic process	GO:0006520	107	0.446
oxoacid metabolic process	GO:0043436	290	0.227
organic acid metabolic process	GO:0006082	292	0.221
organic acid biosynthetic process	GO:0016053	83	0.190
translation	GO:0006412	35	0.179
neuromuscular process	GO:0050905	2	0.163
alpha amino acid metabolic process	GO:1901605	71	0.146
ncrna metabolic process	GO:0034660	8	0.140
cellular amino acid biosynthetic process	GO:0008652	32	0.114
rna metabolic process	GO:0016070	406	0.105
nucleotide metabolic process	GO:0009117	279	0.096
carboxylic acid metabolic process	GO:0019752	289	0.094
molting cycle process	GO:0022404	2	0.086
cerebellar purkinje cell layer development	GO:0021680	2	0.082
brain development	GO:0007420	247	0.081
hair cycle process	GO:0022405	2	0.076
aspartate family amino acid biosynthetic process	GO:0009067	4	0.067
regulation of protein metabolic process	GO:0051246	289	0.064
apoptotic process	GO:0006915	381	0.062
organophosphate metabolic process	GO:0019637	370	0.061
negative regulation of cell death	GO:0060548	229	0.057
nucleobase containing small molecule metabolic process	GO:0055086	316	0.057
neuron death	GO:0070997	127	0.055
regulation of cellular protein metabolic process	GO:0032268	267	0.053
reproduction	GO:0000003	245	0.053
regulation of programmed cell death	GO:0043067	341	0.049
ncrna processing	GO:0034470	3	0.048
regulation of apoptotic process	GO:0042981	335	0.048
posttranscriptional regulation of gene expression	GO:0010608	37	0.047
negative regulation of programmed cell death	GO:0043069	183	0.046
nucleoside phosphate metabolic process	GO:0006753	283	0.046
regulation of neuron death	GO:1901214	115	0.044
epithelium development	GO:0060429	96	0.039
organonitrogen compound biosynthetic process	GO:1901566	167	0.039
l serine metabolic process	GO:0006563	3	0.039
carboxylic acid biosynthetic process	GO:0046394	83	0.036
gland development	GO:0048732	155	0.036
single organism biosynthetic process	GO:0044711	342	0.036
organophosphate biosynthetic process	GO:0090407	143	0.034
neural crest cell differentiation	GO:0014033	2	0.033
head development	GO:0060322	247	0.033
cellular response to stress	GO:0033554	269	0.033
cellular response to hormone stimulus	GO:0032870	247	0.032
transcription dna templated	GO:0006351	377	0.031
developmental process involved in reproduction	GO:0003006	159	0.030
neuron apoptotic process	GO:0051402	88	0.030
neurological system process	GO:0050877	219	0.030
aspartate family amino acid metabolic process	GO:0009066	10	0.030
neural crest cell development	GO:0014032	2	0.029
small molecule biosynthetic process	GO:0044283	124	0.027
alpha amino acid biosynthetic process	GO:1901607	23	0.026
hepaticobiliary system development	GO:0061008	90	0.026
cellular response to endogenous stimulus	GO:0071495	377	0.026
programmed cell death	GO:0012501	392	0.026
glandular epithelial cell differentiation	GO:0002067	4	0.026
multi organism reproductive process	GO:0044703	262	0.025
regulation of cell development	GO:0060284	263	0.025
carbohydrate derivative metabolic process	GO:1901135	346	0.024
branched chain amino acid transport	GO:0015803	2	0.024
anion transport	GO:0006820	178	0.024
reproductive structure development	GO:0048608	128	0.023
cellular amine metabolic process	GO:0044106	38	0.023
sexual reproduction	GO:0019953	148	0.023
ribose phosphate metabolic process	GO:0019693	235	0.023
hair follicle development	GO:0001942	2	0.022
negative regulation of neuron apoptotic process	GO:0043524	45	0.022
cellular response to topologically incorrect protein	GO:0035967	3	0.022
central nervous system development	GO:0007417	311	0.022
nucleoside phosphate biosynthetic process	GO:1901293	102	0.021
single organism reproductive process	GO:0044702	297	0.021
regulation of rna biosynthetic process	GO:2001141	381	0.021
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.020
negative regulation of multicellular organismal process	GO:0051241	203	0.020
glycosyl compound metabolic process	GO:1901657	182	0.020
reproductive system development	GO:0061458	128	0.020
organic anion transport	GO:0015711	132	0.020
multicellular organism reproduction	GO:0032504	233	0.020
negative regulation of neuron death	GO:1901215	69	0.020
regulation of cell differentiation	GO:0045595	320	0.019
positive regulation of cell proliferation	GO:0008284	249	0.019
response to hexose	GO:0009746	144	0.019
sex differentiation	GO:0007548	113	0.018
tissue development	GO:0009888	252	0.018
positive regulation of biosynthetic process	GO:0009891	319	0.018
regulation of transcription dna templated	GO:0006355	374	0.018
nucleoside metabolic process	GO:0009116	179	0.018
purine nucleotide metabolic process	GO:0006163	229	0.018
response to nutrient levels	GO:0031667	370	0.017
purine nucleotide catabolic process	GO:0006195	136	0.017
gamete generation	GO:0007276	124	0.017
negative regulation of biosynthetic process	GO:0009890	168	0.017
response to acid chemical	GO:0001101	222	0.016
response to glucose	GO:0009749	136	0.016
negative regulation of metabolic process	GO:0009892	331	0.016
ribonucleoside metabolic process	GO:0009119	174	0.016
regulation of phosphorus metabolic process	GO:0051174	349	0.016
response to oxidative stress	GO:0006979	186	0.015
negative regulation of cellular metabolic process	GO:0031324	281	0.015
aromatic compound catabolic process	GO:0019439	168	0.015
response to monosaccharide	GO:0034284	159	0.015
reproductive process	GO:0022414	372	0.015
axis specification	GO:0009798	4	0.015
ribonucleotide metabolic process	GO:0009259	231	0.015
nucleotide biosynthetic process	GO:0009165	98	0.014
molting cycle	GO:0042303	3	0.014
regulation of multicellular organismal development	GO:2000026	376	0.014
organelle organization	GO:0006996	266	0.014
response to peptide	GO:1901652	292	0.014
negative regulation of cellular protein metabolic process	GO:0032269	106	0.014
cation transport	GO:0006812	382	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.014
response to other organism	GO:0051707	220	0.014
negative regulation of macromolecule metabolic process	GO:0010605	260	0.014
transmembrane transport	GO:0055085	412	0.014
purine containing compound metabolic process	GO:0072521	253	0.014
response to carbohydrate	GO:0009743	183	0.013
immune system process	GO:0002376	204	0.013
metal ion transport	GO:0030001	289	0.013
negative regulation of protein metabolic process	GO:0051248	114	0.013
positive regulation of cell death	GO:0010942	184	0.013
liver development	GO:0001889	90	0.013
positive regulation of apoptotic process	GO:0043065	154	0.013
rna processing	GO:0006396	22	0.013
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.013
anatomical structure morphogenesis	GO:0009653	298	0.012
lipid storage	GO:0019915	1	0.012
positive regulation of gene expression	GO:0010628	244	0.012
nucleic acid templated transcription	GO:0097659	379	0.012
eye morphogenesis	GO:0048592	4	0.012
response to extracellular stimulus	GO:0009991	380	0.012
purine ribonucleotide metabolic process	GO:0009150	227	0.012
negative regulation of developmental process	GO:0051093	125	0.012
cellular component biogenesis	GO:0044085	368	0.012
regulation of nucleic acid templated transcription	GO:1903506	380	0.012
embryonic axis specification	GO:0000578	1	0.012
response to peptide hormone	GO:0043434	278	0.012
response to inorganic substance	GO:0010035	377	0.012
nucleobase containing compound catabolic process	GO:0034655	152	0.012
positive regulation of response to stimulus	GO:0048584	285	0.012
positive regulation of rna metabolic process	GO:0051254	203	0.011
chemical homeostasis	GO:0048878	292	0.011
homeostatic process	GO:0042592	331	0.011
negative regulation of cellular biosynthetic process	GO:0031327	161	0.011
negative regulation of translation in response to stress	GO:0032055	5	0.011
cellular response to oxygen containing compound	GO:1901701	386	0.011
anterior posterior pattern specification	GO:0009952	1	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.011
ion transmembrane transport	GO:0034220	365	0.011
regulation of phosphate metabolic process	GO:0019220	349	0.011
regulation of rna metabolic process	GO:0051252	391	0.011
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.011
development of primary sexual characteristics	GO:0045137	107	0.011
positive regulation of programmed cell death	GO:0043068	157	0.011
response to decreased oxygen levels	GO:0036293	237	0.011
response to lipopolysaccharide	GO:0032496	191	0.011
hair cycle	GO:0042633	3	0.010
negative regulation of apoptotic process	GO:0043066	181	0.010
regulation of ion transport	GO:0043269	245	0.010
endoplasmic reticulum unfolded protein response	GO:0030968	2	0.010
cellular chemical homeostasis	GO:0055082	247	0.010
response to toxic substance	GO:0009636	133	0.010

Yars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.972
neuropathy	DOID:870	0.972
neuromuscular disease	DOID:440	0.972
charcot marie tooth disease type 2	DOID:0050539	0.972
disease of anatomical entity	DOID:7	0.972
charcot marie tooth disease	DOID:10595	0.972
central nervous system disease	DOID:331	0.019
sensory system disease	DOID:0050155	0.012
eye and adnexa disease	DOID:1492	0.011
eye disease	DOID:5614	0.011

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