Rattus norvegicus

43 known processes

Gch1

GTP cyclohydrolase 1

(Aliases: Gch)

Gch1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to lipopolysaccharideGO:00324961910.270
response to external biotic stimulusGO:00432072210.255
carboxylic acid metabolic processGO:00197522890.226
response to glucocorticoidGO:00513842230.216
regulation of protein metabolic processGO:00512462890.214
response to other organismGO:00517072200.194
negative regulation of metabolic processGO:00098923310.173
regulation of molecular functionGO:00650093980.166
response to biotic stimulusGO:00096072260.158
response to peptideGO:19016522920.151
regulation of rna metabolic processGO:00512523910.151
response to corticosteroidGO:00319602350.135
response to bacteriumGO:00096172000.131
reproductive processGO:00224143720.130
response to oxidative stressGO:00069791860.129
positive regulation of nitrogen compound metabolic processGO:00511733340.125
negative regulation of multicellular organismal processGO:00512412030.122
response to molecule of bacterial originGO:00022371940.122
response to woundingGO:00096112540.116
regulation of rna biosynthetic processGO:20011413810.115
rna metabolic processGO:00160704060.111
positive regulation of phosphorus metabolic processGO:00105622620.108
negative regulation of macromolecule metabolic processGO:00106052600.108
regulation of transcription dna templatedGO:00063553740.101
regulation of catalytic activityGO:00507903040.096
positive regulation of protein metabolic processGO:00512471780.091
regulation of ion transportGO:00432692450.090
response to estrogenGO:00436272320.089
nucleic acid templated transcriptionGO:00976593790.089
response to nutrient levelsGO:00316673700.087
transcription from rna polymerase ii promoterGO:00063662520.085
inflammatory responseGO:00069541500.084
regulation of neuron differentiationGO:00456642080.084
wound healingGO:00420601220.082
positive regulation of nucleic acid templated transcriptionGO:19035081970.082
cellular response to oxygen containing compoundGO:19017013860.081
regulation of phosphorylationGO:00423252480.080
regulation of cell differentiationGO:00455953200.080
response to extracellular stimulusGO:00099913800.079
response to hypoxiaGO:00016662310.078
alpha amino acid metabolic processGO:1901605710.077
response to inorganic substanceGO:00100353770.076
regulation of cell proliferationGO:00421273590.076
rna biosynthetic processGO:00327743800.072
response to oxygen levelsGO:00704822650.071
negative regulation of cellular metabolic processGO:00313242810.070
organic anion transportGO:00157111320.068
response to cytokineGO:00340972150.067
regulation of nervous system developmentGO:00519602640.066
organic acid transportGO:00158491160.065
cellular component assemblyGO:00226073600.065
neurological system processGO:00508772190.065
immune system processGO:00023762040.065
response to estradiolGO:00323551640.064
negative regulation of molecular functionGO:00440921330.064
response to peptide hormoneGO:00434342780.063
response to decreased oxygen levelsGO:00362932370.063
cellular amino acid metabolic processGO:00065201070.063
positive regulation of neurogenesisGO:00507691650.063
regulation of cellular protein metabolic processGO:00322682670.062
positive regulation of cell deathGO:00109421840.062
transcription dna templatedGO:00063513770.062
cell cell signalingGO:00072673350.061
regulation of cellular component organizationGO:00511283680.060
regulation of nucleic acid templated transcriptionGO:19035063800.060
positive regulation of phosphorylationGO:00423271770.059
secretionGO:00469033070.059
regulation of cell projection organizationGO:00313441750.059
positive regulation of multicellular organismal processGO:00512403870.059
cellular response to organic cyclic compoundGO:00714072020.058
regulation of multicellular organismal developmentGO:20000263760.057
positive regulation of macromolecule biosynthetic processGO:00105572470.057
regulation of phosphorus metabolic processGO:00511743490.057
regulation of apoptotic processGO:00429813350.056
protein phosphorylationGO:00064683450.055
catabolic processGO:00090563510.055
positive regulation of response to stimulusGO:00485842850.055
regulation of secretionGO:00510462240.054
cellular response to lipidGO:00713962010.053
cellular catabolic processGO:00442482950.052
regulation of programmed cell deathGO:00430673410.052
intracellular signal transductionGO:00355563140.051
regulation of cell developmentGO:00602842630.051
response to nutrientGO:00075842480.051
response to radiationGO:00093141370.051
positive regulation of phosphate metabolic processGO:00459372620.051
regulation of neuron projection developmentGO:00109751610.050
cellular response to stressGO:00335542690.050
defense responseGO:00069521940.049
hormone transportGO:00099141210.049
regulation of protein phosphorylationGO:00019321830.048
circulatory system processGO:00030131830.048
tissue developmentGO:00098882520.047
locomotionGO:00400112370.047
positive regulation of gene expressionGO:00106282440.047
transmembrane transportGO:00550854120.047
negative regulation of nucleic acid templated transcriptionGO:19035071170.047
organic acid metabolic processGO:00060822920.047
apoptotic processGO:00069153810.046
positive regulation of cellular component organizationGO:00511302000.046
regulation of phosphate metabolic processGO:00192203490.046
regulation of hormone levelsGO:00108171870.046
positive regulation of cell communicationGO:00106472710.046
positive regulation of developmental processGO:00510942830.045
response to mechanical stimulusGO:00096121340.044
response to reactive oxygen speciesGO:00003021200.044
multi organism reproductive processGO:00447032620.044
negative regulation of macromolecule biosynthetic processGO:00105581480.043
response to purine containing compoundGO:00140741260.043
positive regulation of nervous system developmentGO:00519621780.043
single organism biosynthetic processGO:00447113420.043
regulation of cellular amino acid metabolic processGO:000652120.043
positive regulation of cell proliferationGO:00082842490.043
negative regulation of cell deathGO:00605482290.043
regulation of cellular localizationGO:00603412630.042
immune responseGO:00069551040.042
neuron differentiationGO:00301823680.042
negative regulation of cellular biosynthetic processGO:00313271610.042
cellular response to cytokine stimulusGO:00713451270.042
regulation of transcription from rna polymerase ii promoterGO:00063572340.042
cellular response to endogenous stimulusGO:00714953770.042
nitrogen compound transportGO:00717052290.041
response to acid chemicalGO:00011012220.041
regulation of neurogenesisGO:00507672470.041
positive regulation of cellular protein metabolic processGO:00322701670.041
response to organophosphorusGO:00466831020.041
positive regulation of programmed cell deathGO:00430681570.041
cellular response to nitrogen compoundGO:19016992100.041
positive regulation of molecular functionGO:00440932300.040
oxoacid metabolic processGO:00434362900.040
negative regulation of developmental processGO:00510931250.040
localization of cellGO:00516742020.040
cell projection organizationGO:00300303020.039
cellular component biogenesisGO:00440853680.039
regulation of response to external stimulusGO:00321011060.039
response to campGO:0051591910.039
regulation of protein kinase activityGO:00458591050.039
cell motilityGO:00488702020.039
nucleoside phosphate metabolic processGO:00067532830.039
cellular response to hormone stimulusGO:00328702470.039
protein complex biogenesisGO:00702712630.039
synaptic growth at neuromuscular junctionGO:005112410.038
amine metabolic processGO:0009308380.038
cellular ketone metabolic processGO:0042180510.038
regulation of cellular ketone metabolic processGO:0010565270.038
cellular chemical homeostasisGO:00550822470.038
regulation of protein modification processGO:00313991940.038
neuron developmentGO:00486662860.038
positive regulation of signal transductionGO:00099671750.037
regulation of cellular amine metabolic processGO:003323880.037
programmed cell deathGO:00125013920.037
nucleobase containing small molecule metabolic processGO:00550863160.037
cellular amine metabolic processGO:0044106380.036
negative regulation of cell differentiationGO:0045596990.036
organonitrogen compound biosynthetic processGO:19015661670.036
negative regulation of biosynthetic processGO:00098901680.036
positive regulation of nucleobase containing compound metabolic processGO:00459353190.036
positive regulation of transcription dna templatedGO:00458931970.035
organophosphate metabolic processGO:00196373700.035
regulation of reactive oxygen species metabolic processGO:2000377260.035
metal ion homeostasisGO:00550651860.035
cellular response to interleukin 1GO:0071347370.035
response to metal ionGO:00100382530.034
positive regulation of apoptotic processGO:00430651540.034
carboxylic acid transportGO:00469421150.034
negative regulation of programmed cell deathGO:00430691830.034
regulation of transferase activityGO:00513381230.033
positive regulation of cellular amino acid metabolic processGO:004576410.033
anatomical structure morphogenesisGO:00096532980.033
mapk cascadeGO:00001651400.033
positive regulation of neuron differentiationGO:00456661260.033
positive regulation of cellular biosynthetic processGO:00313282950.033
anion transportGO:00068201780.033
cell migrationGO:00164771970.033
negative regulation of rna metabolic processGO:00512531230.032
carbohydrate derivative metabolic processGO:19011353460.032
negative regulation of gene expressionGO:00106291990.032
nucleotide metabolic processGO:00091172790.032
negative regulation of nitrogen compound metabolic processGO:00511721610.031
macromolecular complex assemblyGO:00650032730.031
regulation of intracellular signal transductionGO:19025312180.031
response to gamma radiationGO:0010332240.031
reactive oxygen species metabolic processGO:0072593370.031
negative regulation of cell proliferationGO:00082851190.031
regulation of neuron deathGO:19012141150.031
negative regulation of transcription dna templatedGO:00458921160.031
amino acid transportGO:0006865700.030
negative regulation of nucleobase containing compound metabolic processGO:00459341530.030
defense response to other organismGO:0098542170.030
positive regulation of cell migrationGO:0030335960.030
cellular response to organonitrogen compoundGO:00714171970.030
divalent inorganic cation homeostasisGO:00725071650.029
positive regulation of cell differentiationGO:00455972170.029
carbohydrate metabolic processGO:00059751300.029
agingGO:00075682410.029
homeostatic processGO:00425923310.029
regulation of hydrolase activityGO:00513361430.029
signal releaseGO:00230611450.029
lipid localizationGO:0010876620.028
positive regulation of response to external stimulusGO:0032103510.028
response to temperature stimulusGO:0009266940.028
cellular cation homeostasisGO:00300031800.028
central nervous system developmentGO:00074173110.028
chemical homeostasisGO:00488782920.028
ion homeostasisGO:00508012120.028
positive regulation of biosynthetic processGO:00098913190.028
single organism intracellular transportGO:19025821660.028
positive regulation of cell developmentGO:00107201760.028
positive regulation of catalytic activityGO:00430851840.028
positive regulation of cell motilityGO:2000147970.028
multicellular organism reproductionGO:00325042330.028
hormone secretionGO:00468791150.027
response to ammonium ionGO:0060359710.027
response to dexamethasoneGO:0071548490.027
cellular response to glucocorticoid stimulusGO:0071385680.027
multicellular organismal reproductive processGO:00486092330.027
positive regulation of transportGO:00510502450.026
positive regulation of rna metabolic processGO:00512542030.026
positive regulation of protein modification processGO:00314011420.026
amide transportGO:00428861050.026
reactive nitrogen species metabolic processGO:200105710.026
eosinophil chemotaxisGO:004824530.026
protein complex assemblyGO:00064612630.026
regulation of signal transductionGO:00099663180.026
neuron projection developmentGO:00311752730.025
lipid transportGO:0006869610.025
response to toxic substanceGO:00096361330.025
positive regulation of protein phosphorylationGO:00019341350.025
gastrulationGO:000736920.025
reactive oxygen species biosynthetic processGO:190340980.025
cellular metal ion homeostasisGO:00068751720.025
female pregnancyGO:00075651220.025
carbohydrate derivative biosynthetic processGO:19011371240.024
signal transduction by phosphorylationGO:00230141440.024
positive regulation of signalingGO:00230562700.024
cellular response to lipoteichoic acidGO:007122310.024
single organism reproductive processGO:00447022970.024
protein localizationGO:00081041910.024
ribonucleotide metabolic processGO:00092592310.024
protein transportGO:00150311320.024
response to heatGO:0009408600.024
cation transportGO:00068123820.024
organelle organizationGO:00069962660.024
purine containing compound metabolic processGO:00725212530.024
positive regulation of neuron projection developmentGO:0010976990.024
positive regulation of intracellular signal transductionGO:19025331380.023
cellular response to biotic stimulusGO:0071216590.023
neuron deathGO:00709971270.023
regulation of kinase activityGO:00435491170.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.023
negative regulation of apoptotic processGO:00430661810.023
cytokine mediated signaling pathwayGO:0019221430.022
response to ketoneGO:19016541820.022
circulatory system developmentGO:00723591340.022
cellular component movementGO:00069282480.022
jak stat cascadeGO:0007259260.022
macromolecule catabolic processGO:0009057580.022
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.022
taxisGO:0042330670.022
regulation of cell motilityGO:20001451310.022
sexual reproductionGO:00199531480.022
response to vitaminGO:00332731310.022
cellular homeostasisGO:00197252520.022
cellular response to steroid hormone stimulusGO:0071383930.021
cellular protein localizationGO:00346131220.021
negative regulation of catalytic activityGO:00430861030.021
positive regulation of cell projection organizationGO:00313461110.021
cellular divalent inorganic cation homeostasisGO:00725031620.021
negative regulation of neuron deathGO:1901215690.021
macromolecular complex subunit organizationGO:00439333390.021
regulation of neuron apoptotic processGO:0043523830.020
peptidyl amino acid modificationGO:00181931260.020
secretion by cellGO:00329402480.020
response to insulinGO:00328681330.020
blood circulationGO:00080151830.020
organophosphate biosynthetic processGO:00904071430.020
regulation of ion transmembrane transportGO:00347651210.020
reproductive system developmentGO:00614581280.020
metal ion transportGO:00300012890.020
organic substance catabolic processGO:19015753160.020
neuron apoptotic processGO:0051402880.020
proteolysisGO:00065081750.020
negative regulation of signalingGO:00230571570.020
response to hydrogen peroxideGO:0042542890.020
sequestering of triglycerideGO:003073010.019
positive regulation of cellular amine metabolic processGO:003324030.019
regulation of cellular component movementGO:00512701500.019
positive regulation of rna biosynthetic processGO:19026801970.019
cellular response to corticosteroid stimulusGO:0071384690.019
cellular response to peptide hormone stimulusGO:00713751200.019
response to axon injuryGO:0048678590.019
regulation of transmembrane transportGO:00347621220.019
response to glucoseGO:00097491360.019
behaviorGO:00076102050.019
negative regulation of cellular protein metabolic processGO:00322691060.018
ion transmembrane transportGO:00342203650.018
regulation of proteolysisGO:0030162660.018
regulation of smooth muscle cell proliferationGO:0048660750.018
negative regulation of protein metabolic processGO:00512481140.018
smooth muscle cell proliferationGO:0048659770.018
response to interleukin 1GO:0070555550.018
negative regulation of neurogenesisGO:0050768780.018
regulation of catabolic processGO:00098941130.018
negative regulation of rna biosynthetic processGO:19026791180.018
innate immune responseGO:0045087350.018
negative regulation of neuron apoptotic processGO:0043524450.018
response to starvationGO:0042594590.018
cellular response to molecule of bacterial originGO:0071219560.017
regulation of response to stressGO:00801341260.017
organic hydroxy compound metabolic processGO:19016151150.017
steroid metabolic processGO:0008202730.017
heterocycle catabolic processGO:00467001670.017
cellular response to oxidative stressGO:0034599760.017
response to transition metal nanoparticleGO:19902671220.017
response to growth factorGO:00708481890.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
cellular ion homeostasisGO:00068731840.017
leukocyte cell cell adhesionGO:000715940.017
positive regulation of cytosolic calcium ion concentrationGO:00072041220.017
positive regulation of mapk cascadeGO:0043410920.017
developmental process involved in reproductionGO:00030061590.017
cyclic nucleotide metabolic processGO:0009187800.016
response to carbohydrateGO:00097431830.016
cell adhesionGO:00071551100.016
regenerationGO:00310991630.016
reproductionGO:00000032450.016
cell morphogenesis involved in differentiationGO:00009041190.016
regulation of system processGO:00440572080.016
cellular calcium ion homeostasisGO:00068741600.016
blood vessel developmentGO:0001568690.016
reproductive structure developmentGO:00486081280.016
negative regulation of phosphorus metabolic processGO:0010563800.016
purine nucleotide metabolic processGO:00061632290.016
negative regulation of transportGO:00510511360.016
cellular hormone metabolic processGO:0034754490.016
cytokine productionGO:0001816610.016
positive regulation of cytokine productionGO:0001819420.016
calcium ion homeostasisGO:00550741620.016
single organism behaviorGO:00447081300.016
regulation of anatomical structure morphogenesisGO:00226031410.016
positive regulation of synaptic transmissionGO:0050806620.016
regulation of immune system processGO:00026821230.015
cation transmembrane transportGO:00986552630.015
protein maturationGO:0051604680.015
regulation of synaptic transmissionGO:00508041410.015
intracellular transportGO:00469071850.015
mesoderm developmentGO:000749820.015
leukocyte chemotaxisGO:0030595220.015
response to hexoseGO:00097461440.015
negative regulation of response to stimulusGO:00485851550.015
cellular response to tumor necrosis factorGO:0071356460.015
cellular response to extracellular stimulusGO:0031668730.015
response to alkaloidGO:00432791320.015
glucose homeostasisGO:0042593750.015
protein catabolic processGO:0030163300.015
single organismal cell cell adhesionGO:0016337420.015
response to monosaccharideGO:00342841590.015
maintenance of locationGO:0051235170.015
multi multicellular organism processGO:00447061380.015
cellular response to alcoholGO:0097306870.015
axis specificationGO:000979840.015
synaptic transmissionGO:00072682350.015
formation of primary germ layerGO:000170410.015
cellular nitrogen compound catabolic processGO:00442701630.015
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.015
regulation of cytokine productionGO:0001817560.014
divalent metal ion transportGO:00708381320.014
cellular response to interferon gammaGO:0071346140.014
response to tumor necrosis factorGO:0034612560.014
regulation of protein serine threonine kinase activityGO:0071900640.014
peptide transportGO:0015833970.014
dendrite developmentGO:0016358720.014
single organism catabolic processGO:00447122830.014
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.014
negative regulation of phosphate metabolic processGO:0045936800.014
biological adhesionGO:00226101100.014
response to transforming growth factor betaGO:0071559460.014
regulation of secretion by cellGO:19035302080.014
cellular response to alkaloidGO:0071312250.014
acute inflammatory responseGO:0002526580.014
positive regulation of cellular component movementGO:00512721020.014
head developmentGO:00603222470.014
purine ribonucleotide metabolic processGO:00091502270.014
gamete generationGO:00072761240.014
negative regulation of cell communicationGO:00106481580.014
cytoplasmic transportGO:00164821150.014
regulation of interleukin 6 productionGO:0032675120.014
negative regulation of cell developmentGO:0010721820.014
regulation of insulin secretionGO:0050796650.013
cytosolic calcium ion homeostasisGO:00514801400.013
defense response to gram positive bacteriumGO:005083020.013
protein oligomerizationGO:00512591910.013
regulation of protein maturationGO:1903317500.013
cellular response to dexamethasone stimulusGO:0071549360.013
positive regulation of transferase activityGO:0051347810.013
response to ethanolGO:00454711620.013
muscle cell proliferationGO:0033002840.013
hexose metabolic processGO:0019318580.013
macromolecule localizationGO:00330362520.013
response to amino acidGO:0043200750.013
regulation of map kinase activityGO:0043405530.013
insulin secretionGO:0030073690.013
lipid metabolic processGO:00066292830.013
positive regulation of secretionGO:00510471400.013
cellular response to external stimulusGO:00714961180.013
carbohydrate homeostasisGO:0033500750.013
single organism carbohydrate metabolic processGO:00447231180.013
regulation of peptidase activityGO:0052547550.013
chemosensory behaviorGO:000763520.013
lipid storageGO:001991510.013
regulation of locomotionGO:00400121480.013
response to activityGO:0014823730.013
calcium ion transportGO:00068161310.013
regulation of anion transportGO:0044070430.012
neutrophil migrationGO:1990266120.012
response to ionizing radiationGO:0010212590.012
olfactory behaviorGO:004204820.012
regulation of blood pressureGO:0008217830.012
gland developmentGO:00487321550.012
regulation of cell migrationGO:00303341280.012
acute phase responseGO:0006953200.012
g protein coupled receptor signaling pathwayGO:00071862420.012
peptide hormone secretionGO:0030072840.012
cellular macromolecule localizationGO:00707271220.012
gliogenesisGO:0042063930.012
vascular process in circulatory systemGO:0003018960.012
positive regulation of ion transportGO:0043270940.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
negative regulation of secretionGO:0051048820.012
cellular response to mechanical stimulusGO:0071260480.012
cellular modified amino acid biosynthetic processGO:0042398180.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
cellular response to lipopolysaccharideGO:0071222550.012
cell type specific apoptotic processGO:00972851340.012
regulation of cell adhesionGO:0030155520.012
organic cyclic compound catabolic processGO:19013611750.012
positive regulation of hydrolase activityGO:0051345860.011
regulation of protein transportGO:0051223680.011
negative regulation of natural killer cell mediated immunityGO:000271640.011
response to vitamin dGO:0033280340.011
immune effector processGO:0002252530.011
regulation of dendrite developmentGO:0050773590.011
positive regulation of catabolic processGO:0009896780.011
tumor necrosis factor mediated signaling pathwayGO:003320940.011
brain developmentGO:00074202470.011
exocytosisGO:0006887600.011
amine transportGO:0015837570.011
cellular response to ethanolGO:0071361130.011
peptide biosynthetic processGO:004304330.011
erk1 and erk2 cascadeGO:0070371480.011
sensory perceptionGO:00076001010.011
cellular response to peptideGO:19016531330.011
endocytosisGO:0006897840.011
multicellular organism growthGO:003526410.011
regulation of hormone secretionGO:00468831060.011
ncrna processingGO:003447030.011
response to amphetamineGO:0001975250.011
ribose phosphate metabolic processGO:00196932350.011
regulation of immune responseGO:0050776550.011
peptide secretionGO:0002790860.011
cellular response to growth factor stimulusGO:00713631620.011
cellular response to insulin stimulusGO:0032869810.011
positive regulation of cellular catabolic processGO:0031331710.011
salivary gland developmentGO:000743130.011
positive regulation of kinase activityGO:0033674770.011
myeloid leukocyte migrationGO:0097529200.011
regulation of peptide transportGO:0090087870.010
cellular response to carbohydrate stimulusGO:0071322720.010
cation homeostasisGO:00550801950.010
monosaccharide metabolic processGO:0005996610.010
response to high density lipoprotein particleGO:005509920.010
coenzyme metabolic processGO:0006732860.010
growthGO:00400071650.010
regulation of vasculature developmentGO:1901342440.010
regulation of apoptotic signaling pathwayGO:2001233130.010
protein processingGO:0016485680.010
regulation of peptide secretionGO:0002791820.010
regulation of metal ion transportGO:00109591180.010
defense response to gram negative bacteriumGO:005082930.010
developmental growthGO:00485891000.010
tumor necrosis factor superfamily cytokine productionGO:0071706130.010
vesicle mediated transportGO:00161921810.010
negative regulation of signal transductionGO:0009968830.010
tissue regenerationGO:0042246360.010

Gch1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.031
disease of anatomical entityDOID:700.031
disease of metabolismDOID:001466700.021
nervous system diseaseDOID:86300.015
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.014
connective tissue diseaseDOID:6500.012
organ system cancerDOID:005068600.012
gastrointestinal system cancerDOID:311900.012
stomach cancerDOID:1053400.012