Rattus norvegicus

75 known processes

Gclm

glutamate cysteine ligase, modifier subunit

(Aliases: Glclr)

Gclm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid biosynthetic processGO:0008652320.333
response to inorganic substanceGO:00100353770.230
response to oxidative stressGO:00069791860.215
organonitrogen compound biosynthetic processGO:19015661670.197
regulation of apoptotic processGO:00429813350.195
regulation of programmed cell deathGO:00430673410.181
carboxylic acid metabolic processGO:00197522890.177
single organism biosynthetic processGO:00447113420.159
organic acid biosynthetic processGO:0016053830.133
negative regulation of cell deathGO:00605482290.133
amide biosynthetic processGO:0043604100.127
cellular modified amino acid biosynthetic processGO:0042398180.123
response to oxygen levelsGO:00704822650.121
carboxylic acid biosynthetic processGO:0046394830.119
small molecule biosynthetic processGO:00442831240.111
response to metal ionGO:00100382530.106
response to carbohydrateGO:00097431830.103
negative regulation of programmed cell deathGO:00430691830.100
neuron apoptotic processGO:0051402880.097
cellular amino acid metabolic processGO:00065201070.089
organic acid metabolic processGO:00060822920.084
regulation of intracellular signal transductionGO:19025312180.083
nucleobase containing small molecule metabolic processGO:00550863160.083
response to hypoxiaGO:00016662310.081
cellular modified amino acid metabolic processGO:0006575610.078
apoptotic processGO:00069153810.074
cellular response to oxygen containing compoundGO:19017013860.072
cellular response to reactive oxygen speciesGO:0034614550.069
response to ethanolGO:00454711620.069
response to estradiolGO:00323551640.067
central nervous system developmentGO:00074173110.067
cellular response to oxidative stressGO:0034599760.064
alpha amino acid metabolic processGO:1901605710.063
response to decreased oxygen levelsGO:00362932370.063
single organism catabolic processGO:00447122830.062
neuron projection developmentGO:00311752730.060
neuron differentiationGO:00301823680.060
intracellular signal transductionGO:00355563140.059
response to estrogenGO:00436272320.059
programmed cell deathGO:00125013920.057
catabolic processGO:00090563510.055
regulation of secretionGO:00510462240.054
response to monosaccharideGO:00342841590.053
oxoacid metabolic processGO:00434362900.053
response to nutrient levelsGO:00316673700.053
negative regulation of apoptotic processGO:00430661810.053
brain developmentGO:00074202470.052
response to vitaminGO:00332731310.049
response to extracellular stimulusGO:00099913800.049
cellular catabolic processGO:00442482950.048
protein complex assemblyGO:00064612630.048
response to acid chemicalGO:00011012220.048
regulation of response to stressGO:00801341260.047
regulation of cell maturationGO:190342930.047
response to nutrientGO:00075842480.047
response to corticosteroidGO:00319602350.046
peptide metabolic processGO:0006518320.045
cellular component assemblyGO:00226073600.045
cellular ketone metabolic processGO:0042180510.043
neurological system processGO:00508772190.043
cellular response to stressGO:00335542690.043
positive regulation of cell deathGO:00109421840.042
cellular component biogenesisGO:00440853680.042
regulation of cellular component organizationGO:00511283680.041
reproductive processGO:00224143720.041
response to nitrosative stressGO:005140920.041
negative regulation of neuron apoptotic processGO:0043524450.041
organelle organizationGO:00069962660.040
response to reactive oxygen speciesGO:00003021200.040
regulation of protein metabolic processGO:00512462890.039
response to peptideGO:19016522920.039
protein complex subunit organizationGO:00718223020.039
small molecule catabolic processGO:0044282590.039
secretion by cellGO:00329402480.038
cell projection organizationGO:00300303020.038
response to toxic substanceGO:00096361330.038
head developmentGO:00603222470.037
multi organism reproductive processGO:00447032620.036
macromolecular complex assemblyGO:00650032730.036
response to biotic stimulusGO:00096072260.036
multicellular organismal reproductive processGO:00486092330.035
negative regulation of cell communicationGO:00106481580.035
transmembrane transportGO:00550854120.035
response to growth factorGO:00708481890.034
cellular response to endogenous stimulusGO:00714953770.034
developmental process involved in reproductionGO:00030061590.034
reactive oxygen species metabolic processGO:0072593370.033
anterior posterior pattern specificationGO:000995210.033
nucleoside phosphate metabolic processGO:00067532830.033
regulation of multicellular organismal developmentGO:20000263760.032
organophosphate metabolic processGO:00196373700.032
regulation of transcription dna templatedGO:00063553740.032
cellular amide metabolic processGO:0043603440.032
cell junction maintenanceGO:003433110.032
homeostatic processGO:00425923310.032
organophosphate biosynthetic processGO:00904071430.032
single organism carbohydrate metabolic processGO:00447231180.032
regulation of cellular protein metabolic processGO:00322682670.032
response to hydrogen peroxideGO:0042542890.031
regulation of protein modification processGO:00313991940.030
regulation of neuron deathGO:19012141150.030
response to other organismGO:00517072200.030
neuron deathGO:00709971270.030
sulfur compound metabolic processGO:0006790700.030
response to glucocorticoidGO:00513842230.030
cellular response to organic cyclic compoundGO:00714072020.030
regulation of signal transductionGO:00099663180.029
cell part morphogenesisGO:00329901230.029
negative regulation of multicellular organismal processGO:00512412030.029
anatomical structure morphogenesisGO:00096532980.029
neuron developmentGO:00486662860.028
organ formationGO:004864530.028
cellular homeostasisGO:00197252520.028
positive regulation of nervous system developmentGO:00519621780.028
positive regulation of multicellular organismal processGO:00512403870.027
agingGO:00075682410.027
intracellular transportGO:00469071850.027
regulation of neuron projection developmentGO:00109751610.027
ribonucleotide metabolic processGO:00092592310.027
regulation of phosphorus metabolic processGO:00511743490.026
actin filament based processGO:0030029860.026
organic hydroxy compound metabolic processGO:19016151150.026
regulation of cell differentiationGO:00455953200.026
regulation of nervous system developmentGO:00519602640.026
macromolecular complex subunit organizationGO:00439333390.026
purine containing compound metabolic processGO:00725212530.026
regulation of cell developmentGO:00602842630.025
cellular response to growth factor stimulusGO:00713631620.025
single organism reproductive processGO:00447022970.025
cation transportGO:00068123820.025
response to vitamin eGO:0033197240.024
organic substance catabolic processGO:19015753160.024
cell projection morphogenesisGO:00488581230.024
forebrain developmentGO:0030900980.024
purine containing compound catabolic processGO:00725231380.024
cellular response to cytokine stimulusGO:00713451270.024
negative regulation of signalingGO:00230571570.024
positive regulation of developmental processGO:00510942830.023
intracellular protein transportGO:0006886790.023
response to woundingGO:00096112540.023
carbohydrate metabolic processGO:00059751300.023
response to glucoseGO:00097491360.023
response to peptide hormoneGO:00434342780.023
regulation of neurogenesisGO:00507672470.023
response to ketoneGO:19016541820.023
secretionGO:00469033070.023
positive regulation of phosphate metabolic processGO:00459372620.022
purine nucleotide metabolic processGO:00061632290.022
locomotionGO:00400112370.022
ras protein signal transductionGO:0007265290.022
carbohydrate derivative metabolic processGO:19011353460.022
positive regulation of transportGO:00510502450.022
positive regulation of neurogenesisGO:00507691650.022
amine metabolic processGO:0009308380.022
negative regulation of neuron deathGO:1901215690.022
cellular amine metabolic processGO:0044106380.022
anion transportGO:00068201780.022
protein complex biogenesisGO:00702712630.022
chemical homeostasisGO:00488782920.022
macromolecule localizationGO:00330362520.021
cell fate determinationGO:000170920.021
small gtpase mediated signal transductionGO:0007264360.021
growthGO:00400071650.021
ribonucleoside triphosphate metabolic processGO:00091991410.021
cell growthGO:00160491040.021
regulation of neuron differentiationGO:00456642080.021
regulation of rna metabolic processGO:00512523910.021
ribose phosphate metabolic processGO:00196932350.021
response to bacteriumGO:00096172000.021
response to cadmium ionGO:0046686350.021
ribonucleoside metabolic processGO:00091191740.021
gastrulationGO:000736920.021
cofactor metabolic processGO:0051186950.020
regulation of cellular localizationGO:00603412630.020
cell cell signalingGO:00072673350.020
nucleotide metabolic processGO:00091172790.020
positive regulation of nitrogen compound metabolic processGO:00511733340.020
amide transportGO:00428861050.020
organic cyclic compound catabolic processGO:19013611750.020
nucleoside metabolic processGO:00091161790.020
cellular response to fluid shear stressGO:007149840.020
neuron projection morphogenesisGO:00488121220.020
positive regulation of phosphorus metabolic processGO:00105622620.020
dna metabolic processGO:0006259960.020
protein oligomerizationGO:00512591910.020
cellular lipid metabolic processGO:00442552080.019
development of primary sexual characteristicsGO:00451371070.019
aromatic compound catabolic processGO:00194391680.019
regenerationGO:00310991630.019
response to hexoseGO:00097461440.019
regulation of cellular amine metabolic processGO:003323880.019
axis specificationGO:000979840.019
negative regulation of protein metabolic processGO:00512481140.019
reproductive system developmentGO:00614581280.019
positive regulation of apoptotic processGO:00430651540.019
lipid metabolic processGO:00066292830.019
negative regulation of metabolic processGO:00098923310.019
multicellular organism reproductionGO:00325042330.019
cellular component movementGO:00069282480.019
purine nucleoside metabolic processGO:00422781690.019
cellular component morphogenesisGO:00329891550.019
cytokinetic processGO:003250610.018
cellular response to hormone stimulusGO:00328702470.018
rhythmic processGO:00485111560.018
bmp signaling pathwayGO:003050940.018
reproductionGO:00000032450.018
cell morphogenesis involved in differentiationGO:00009041190.018
positive regulation of biosynthetic processGO:00098913190.018
protein phosphorylationGO:00064683450.018
circulatory system developmentGO:00723591340.018
metal ion transportGO:00300012890.018
neuronal action potentialGO:0019228350.018
tissue developmentGO:00098882520.018
cellular response to superoxideGO:007145160.018
regulation of cellular response to stressGO:0080135490.018
circulatory system processGO:00030131830.018
response to external biotic stimulusGO:00432072210.018
carbohydrate derivative biosynthetic processGO:19011371240.018
regulation of catalytic activityGO:00507903040.018
regulation of cell growthGO:0001558850.017
cellular chemical homeostasisGO:00550822470.017
proteolysisGO:00065081750.017
single organism cellular localizationGO:19025801020.017
negative regulation of transportGO:00510511360.017
negative regulation of macromolecule metabolic processGO:00106052600.017
cell morphogenesisGO:00009021420.017
nucleoside triphosphate catabolic processGO:00091431230.017
response to insulinGO:00328681330.017
positive regulation of cellular amine metabolic processGO:003324030.017
regulation of secretion by cellGO:19035302080.017
response to cytokineGO:00340972150.017
purine ribonucleotide metabolic processGO:00091502270.017
vesicle mediated transportGO:00161921810.017
heterocycle catabolic processGO:00467001670.016
regulation of cellular ketone metabolic processGO:0010565270.016
nucleoside catabolic processGO:00091641260.016
glycosyl compound catabolic processGO:19016581260.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
rna biosynthetic processGO:00327743800.016
oxidation reduction processGO:00551143040.016
synaptic growth at neuromuscular junctionGO:005112410.016
positive regulation of cell projection organizationGO:00313461110.016
cellular carbohydrate metabolic processGO:0044262720.016
muscle system processGO:00030121150.016
glucose homeostasisGO:0042593750.016
response to activityGO:0014823730.016
negative regulation of molecular functionGO:00440921330.015
positive regulation of neuron projection developmentGO:0010976990.015
gamete generationGO:00072761240.015
peptide transportGO:0015833970.015
regulation of cell projection organizationGO:00313441750.015
transcription dna templatedGO:00063513770.015
exocytosisGO:0006887600.015
response to amino acidGO:0043200750.015
regulation of cellular amino acid metabolic processGO:000652120.015
peptide hormone secretionGO:0030072840.015
positive regulation of molecular functionGO:00440932300.015
cytoplasmic transportGO:00164821150.015
cellular response to lipidGO:00713962010.015
cellular response to organonitrogen compoundGO:00714171970.015
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.015
kidney developmentGO:0001822670.015
behaviorGO:00076102050.015
hormone transportGO:00099141210.015
ribonucleoside catabolic processGO:00424541260.015
regulation of molecular functionGO:00650093980.014
purine ribonucleoside catabolic processGO:00461301240.014
regulation of locomotionGO:00400121480.014
coenzyme metabolic processGO:0006732860.014
metaphase anaphase transition of mitotic cell cycleGO:000709110.014
regulation of peptide transportGO:0090087870.014
regulation of phosphorylationGO:00423252480.014
defense responseGO:00069521940.014
modification dependent protein catabolic processGO:0019941140.014
actin cytoskeleton organizationGO:0030036730.014
cytoskeleton organizationGO:00070101110.014
nitrogen compound transportGO:00717052290.014
nucleoside phosphate catabolic processGO:19012921400.014
peptide secretionGO:0002790860.014
positive regulation of signalingGO:00230562700.014
epithelium developmentGO:0060429960.014
regulation of rna biosynthetic processGO:20011413810.014
rna localizationGO:000640340.014
regulation of synaptic transmissionGO:00508041410.014
sexual reproductionGO:00199531480.014
single organism intracellular transportGO:19025821660.014
response to fatty acidGO:0070542650.014
multi multicellular organism processGO:00447061380.014
embryonic axis specificationGO:000057810.014
muscle cell proliferationGO:0033002840.014
male gamete generationGO:0048232990.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
negative regulation of cellular metabolic processGO:00313242810.013
nucleoside triphosphate metabolic processGO:00091411440.013
learning or memoryGO:0007611900.013
regulation of hormone levelsGO:00108171870.013
carbohydrate derivative catabolic processGO:19011361470.013
purine ribonucleotide catabolic processGO:00091541360.013
positive regulation of lipid catabolic processGO:005099640.013
regulation of embryonic developmentGO:004599520.013
negative regulation of cellular protein metabolic processGO:00322691060.013
regulation of cellular component movementGO:00512701500.013
purine nucleoside catabolic processGO:00061521240.013
regulation of response to external stimulusGO:00321011060.013
signal releaseGO:00230611450.013
synaptic transmissionGO:00072682350.013
organophosphate catabolic processGO:00464341480.013
regulation of anatomical structure sizeGO:00900661350.013
establishment of protein localizationGO:00451841410.013
response to hyperoxiaGO:0055093450.013
alcohol metabolic processGO:0006066770.013
cell motilityGO:00488702020.013
female pregnancyGO:00075651220.013
transmission of nerve impulseGO:0019226420.013
positive regulation of cellular biosynthetic processGO:00313282950.013
cellular response to nitrogen compoundGO:19016992100.013
purine ribonucleoside metabolic processGO:00461281680.012
chemotaxisGO:0006935660.012
ribonucleotide catabolic processGO:00092611360.012
mesonephric epithelium developmentGO:0072163140.012
axon developmentGO:0061564960.012
negative regulation of developmental processGO:00510931250.012
negative regulation of stress activated mapk cascadeGO:003287340.012
single organism behaviorGO:00447081300.012
positive regulation of phosphorylationGO:00423271770.012
regulation of nucleic acid templated transcriptionGO:19035063800.012
axonogenesisGO:0007409710.012
reproductive structure developmentGO:00486081280.012
endosome organizationGO:000703230.012
divalent inorganic cation transportGO:00725111340.012
regulation of cell motilityGO:20001451310.012
cellular response to oxygen levelsGO:0071453600.012
ion transmembrane transportGO:00342203650.012
rab protein signal transductionGO:003248210.012
regulation of neuron apoptotic processGO:0043523830.012
negative regulation of phosphate metabolic processGO:0045936800.012
regulation of synaptic plasticityGO:0048167700.012
phospholipid metabolic processGO:0006644610.012
purine nucleotide catabolic processGO:00061951360.012
nucleoside phosphate biosynthetic processGO:19012931020.012
regulation of blood circulationGO:19035221100.012
nucleobase containing compound catabolic processGO:00346551520.012
inorganic ion transmembrane transportGO:00986602290.012
nucleic acid templated transcriptionGO:00976593790.012
single organism membrane organizationGO:0044802740.012
cellular macromolecule localizationGO:00707271220.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
regulation of intracellular protein transportGO:0033157340.012
response to radiationGO:00093141370.012
negative regulation of signal transductionGO:0009968830.012
positive regulation of cell differentiationGO:00455972170.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
cell adhesionGO:00071551100.012
sex differentiationGO:00075481130.012
negative regulation of secretionGO:0051048820.012
cognitionGO:0050890920.011
carbohydrate homeostasisGO:0033500750.011
protein homooligomerizationGO:0051260910.011
hormone secretionGO:00468791150.011
cytoskeleton dependent cytokinesisGO:006164020.011
positive regulation of cell developmentGO:00107201760.011
mesonephros developmentGO:0001823140.011
cellular component maintenanceGO:004395440.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
regulation of sister chromatid segregationGO:003304510.011
regulation of protein phosphorylationGO:00019321830.011
regulation of growthGO:00400081050.011
negative regulation of catalytic activityGO:00430861030.011
organonitrogen compound catabolic processGO:19015651790.011
membrane organizationGO:0061024940.011
regulation of mitotic sister chromatid separationGO:001096510.011
regulation of membrane potentialGO:00423911100.011
regulation of cell proliferationGO:00421273590.011
glutathione metabolic processGO:0006749150.011
positive regulation of intracellular protein transportGO:0090316200.011
b cell differentiationGO:003018320.011
organic acid transportGO:00158491160.011
regulation of kinase activityGO:00435491170.011
positive regulation of cellular component organizationGO:00511302000.011
negative regulation of cell cycle phase transitionGO:190198840.010
negative regulation of nervous system developmentGO:0051961790.010
telencephalon developmentGO:0021537620.010
positive regulation of programmed cell deathGO:00430681570.010
cellular response to metal ionGO:0071248550.010
centrosome localizationGO:005164210.010
pallium developmentGO:0021543420.010
regulation of intracellular transportGO:0032386650.010
regulation of insulin secretionGO:0050796650.010
tube developmentGO:0035295890.010
cellular response to hydrogen peroxideGO:0070301420.010
regulation of phosphate metabolic processGO:00192203490.010
mesonephric tubule developmentGO:0072164140.010
blood circulationGO:00080151830.010
nucleotide catabolic processGO:00091661390.010
muscle tissue developmentGO:0060537580.010
dna replicationGO:0006260370.010
lipid localizationGO:0010876620.010
regulation of peptide secretionGO:0002791820.010

Gclm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.015
disease of cellular proliferationDOID:1456600.013