Rattus norvegicus

0 known processes

Trim28

tripartite motif-containing 28

(Aliases: Tif1b,Krip1,Kap1)

Trim28 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of mrna splicing via spliceosomeGO:004802430.801
regulation of alternative mrna splicing via spliceosomeGO:000038120.655
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.572
Human Mouse
negative regulation of rna metabolic processGO:00512531230.452
Human Mouse
organelle organizationGO:00069962660.418
Fly
regulation of rna metabolic processGO:00512523910.400
Human Mouse
negative regulation of nitrogen compound metabolic processGO:00511721610.345
Human Mouse
positive regulation of macromolecule biosynthetic processGO:00105572470.331
Mouse
cellular component movementGO:00069282480.311
Fly
regulation of nucleic acid templated transcriptionGO:19035063800.310
Human Mouse
rna metabolic processGO:00160704060.304
Human Mouse
negative regulation of nucleobase containing compound metabolic processGO:00459341530.304
Human Mouse
negative regulation of transcription dna templatedGO:00458921160.294
Human Mouse
negative regulation of rna splicingGO:003311930.286
single organism organelle organizationGO:19025891800.284
nucleic acid templated transcriptionGO:00976593790.275
Human Mouse
transcription from rna polymerase ii promoterGO:00063662520.272
Mouse
negative regulation of biosynthetic processGO:00098901680.243
Human Mouse
transcription dna templatedGO:00063513770.234
Human Mouse
macromolecular complex subunit organizationGO:00439333390.217
Human Fly
cell migrationGO:00164771970.209
single organism reproductive processGO:00447022970.205
Mouse
alternative mrna splicing via spliceosomeGO:000038040.205
negative regulation of rna biosynthetic processGO:19026791180.197
Human Mouse
negative regulation of nucleic acid templated transcriptionGO:19035071170.196
Human Mouse
regulation of transcription from rna polymerase ii promoterGO:00063572340.192
Mouse
positive regulation of nucleic acid templated transcriptionGO:19035081970.189
Mouse
positive regulation of rna metabolic processGO:00512542030.185
Mouse
endocytosisGO:0006897840.179
negative regulation of gene expressionGO:00106291990.176
Human Mouse
reproductive processGO:00224143720.170
Mouse
protein modification by small protein conjugation or removalGO:0070647350.159
Human
regulation of rna biosynthetic processGO:20011413810.157
Human Mouse
regulation of transcription dna templatedGO:00063553740.153
Human Mouse
positive regulation of gene expressionGO:00106282440.148
Mouse
rna biosynthetic processGO:00327743800.147
Human Mouse
negative regulation of macromolecule metabolic processGO:00106052600.146
Human Mouse
reproductionGO:00000032450.146
negative regulation of cellular metabolic processGO:00313242810.122
Human Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353190.120
Human Mouse
mrna splicing via spliceosomeGO:000039870.102
positive regulation of nitrogen compound metabolic processGO:00511733340.099
Human Mouse
mrna metabolic processGO:0016071200.098
mrna processingGO:0006397140.097
cell motilityGO:00488702020.092
protein complex subunit organizationGO:00718223020.091
Human
histone h3 acetylationGO:004396620.090
regulation of mrna processingGO:005068450.087
negative regulation of metabolic processGO:00098923310.084
Human Mouse
spindle organizationGO:000705120.083
positive regulation of transcription dna templatedGO:00458931970.082
Mouse
agingGO:00075682410.082
cell morphogenesis involved in neuron differentiationGO:00486671060.079
Fly
circulatory system developmentGO:00723591340.076
neuron differentiationGO:00301823680.075
Fly
positive regulation of biosynthetic processGO:00098913190.073
Mouse
chromatin modificationGO:0016568330.073
regulation of cell proliferationGO:00421273590.072
negative regulation of developmental processGO:00510931250.068
carbohydrate metabolic processGO:00059751300.067
mitotic spindle organizationGO:000705220.067
multicellular organism reproductionGO:00325042330.067
negative regulation of signalingGO:00230571570.067
cellular ketone metabolic processGO:0042180510.067
response to toxic substanceGO:00096361330.066
negative regulation of cellular biosynthetic processGO:00313271610.063
Human Mouse
lens development in camera type eyeGO:0002088130.063
viral transcriptionGO:001908320.062
chromatin assembly or disassemblyGO:000633310.061
central nervous system developmentGO:00074173110.061
chromosome organizationGO:0051276360.060
Fly
anatomical structure morphogenesisGO:00096532980.060
Mouse Fly
cellular response to organic cyclic compoundGO:00714072020.060
neuron projection developmentGO:00311752730.058
Fly
regulation of cell motilityGO:20001451310.057
nitrogen compound transportGO:00717052290.056
single organism carbohydrate metabolic processGO:00447231180.053
regulation of cell cycleGO:0051726730.052
response to extracellular stimulusGO:00099913800.047
sex differentiationGO:00075481130.045
regulation of rna splicingGO:004348460.045
cell part morphogenesisGO:00329901230.044
Fly
gliogenesisGO:0042063930.044
vesicle mediated transportGO:00161921810.044
negative regulation of multicellular organismal processGO:00512412030.043
regulation of cellular protein metabolic processGO:00322682670.043
negative regulation of cell differentiationGO:0045596990.042
locomotionGO:00400112370.042
Fly
negative regulation of cell communicationGO:00106481580.042
histone h3 k9 methylationGO:005156710.041
peptidyl amino acid modificationGO:00181931260.041
behaviorGO:00076102050.039
cell cycleGO:00070491010.039
immune system processGO:00023762040.039
Human
response to inorganic substanceGO:00100353770.038
multi organism reproductive processGO:00447032620.038
Mouse
homeostatic processGO:00425923310.038
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.038
Mouse
gonad developmentGO:00084061040.037
reproductive system developmentGO:00614581280.037
Mouse
gamete generationGO:00072761240.037
regulation of cellular amino acid metabolic processGO:000652120.036
axis specificationGO:000979840.036
chemotaxisGO:0006935660.036
Fly
receptor mediated endocytosisGO:0006898420.036
chromatin organizationGO:0006325340.036
Fly
response to nutrient levelsGO:00316673700.035
histone methylationGO:001657130.035
response to ketoneGO:19016541820.035
neuron projection guidanceGO:0097485240.035
Fly
cell projection organizationGO:00300303020.035
Fly
cellular response to organonitrogen compoundGO:00714171970.034
regulation of cellular ketone metabolic processGO:0010565270.034
regulation of cellular component movementGO:00512701500.034
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:000037770.033
regulation of gene expression epigeneticGO:0040029100.033
Mouse
developmental process involved in reproductionGO:00030061590.032
Mouse
response to fungicideGO:0060992200.032
negative regulation of signal transductionGO:0009968830.032
tissue developmentGO:00098882520.032
Mouse
multicellular organismal reproductive processGO:00486092330.032
sexual reproductionGO:00199531480.031
negative regulation of cell proliferationGO:00082851190.031
regulation of molecular functionGO:00650093980.031
negative regulation of mrna splicing via spliceosomeGO:004802520.031
regulation of cellular localizationGO:00603412630.031
Human
cellular response to growth factor stimulusGO:00713631620.031
erythrocyte differentiationGO:003021810.031
negative regulation of cell deathGO:00605482290.031
regulation of protein metabolic processGO:00512462890.031
regulation of cell differentiationGO:00455953200.030
protein dna complex disassemblyGO:003298610.030
development of primary sexual characteristicsGO:00451371070.030
positive regulation of cell differentiationGO:00455972170.030
calcium ion homeostasisGO:00550741620.029
cell morphogenesis involved in differentiationGO:00009041190.029
Mouse Fly
regulation of dna methylationGO:004403060.029
positive regulation of multicellular organismal processGO:00512403870.029
anatomical structure formation involved in morphogenesisGO:0048646830.029
positive regulation of cellular biosynthetic processGO:00313282950.029
Mouse
positive regulation of nervous system developmentGO:00519621780.029
regulation of protein modification processGO:00313991940.029
carboxylic acid metabolic processGO:00197522890.029
dna metabolic processGO:0006259960.028
Human Mouse
cellular component assemblyGO:00226073600.028
Human
negative regulation of g protein coupled receptor protein signaling pathwayGO:0045744150.028
regulation of canonical wnt signaling pathwayGO:006082840.028
oxoacid metabolic processGO:00434362900.028
regulation of response to stressGO:00801341260.027
Human
single organism behaviorGO:00447081300.027
regulation of neurogenesisGO:00507672470.027
rna splicingGO:0008380110.026
protein ubiquitinationGO:0016567280.026
Human
secretionGO:00469033070.026
cell cycle checkpointGO:000007520.026
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.026
cellular amine metabolic processGO:0044106380.025
innate immune responseGO:0045087350.025
Human
positive regulation of protein metabolic processGO:00512471780.025
regulation of multicellular organismal developmentGO:20000263760.024
catabolic processGO:00090563510.024
negative regulation of macromolecule biosynthetic processGO:00105581480.024
Human Mouse
apoptotic processGO:00069153810.024
regulation of cell developmentGO:00602842630.024
monosaccharide metabolic processGO:0005996610.024
embryo developmentGO:0009790490.024
Mouse
transmission of nerve impulseGO:0019226420.024
cellular chemical homeostasisGO:00550822470.024
cellular macromolecular complex assemblyGO:0034622580.024
regulation of cellular component organizationGO:00511283680.023
inflammatory responseGO:00069541500.023
macromolecular complex assemblyGO:00650032730.023
Human
regenerationGO:00310991630.023
neuron developmentGO:00486662860.022
Fly
positive regulation of transcription factor import into nucleusGO:004299340.022
Human
response to growth factorGO:00708481890.022
multi multicellular organism processGO:00447061380.022
Mouse
neuronal action potentialGO:0019228350.022
macromolecule localizationGO:00330362520.022
Human
programmed cell deathGO:00125013920.022
glucose metabolic processGO:0006006520.021
chromatin remodelingGO:000633830.021
peptide biosynthetic processGO:004304330.021
regulation of proteasomal protein catabolic processGO:006113640.021
monocarboxylic acid metabolic processGO:00327871520.020
cellular response to extracellular stimulusGO:0031668730.020
nucleocytoplasmic transportGO:0006913480.020
Human
response to biotic stimulusGO:00096072260.020
divalent inorganic cation homeostasisGO:00725071650.020
positive regulation of cell proliferationGO:00082842490.020
negative regulation of striated muscle contractionGO:004598820.020
cell cycle processGO:0022402570.020
gastrulationGO:000736920.019
response to estradiolGO:00323551640.019
defense responseGO:00069521940.019
Human
cell adhesionGO:00071551100.019
regulation of nervous system developmentGO:00519602640.019
cytoskeleton organizationGO:00070101110.019
cellular component biogenesisGO:00440853680.019
Human
regulation of fat cell differentiationGO:004559830.018
positive regulation of rna biosynthetic processGO:19026801970.018
Mouse
cellular response to nitrogen compoundGO:19016992100.018
carbohydrate derivative metabolic processGO:19011353460.018
neurological system processGO:00508772190.018
response to temperature stimulusGO:0009266940.018
regulation of signal transductionGO:00099663180.017
purine ribonucleotide metabolic processGO:00091502270.017
rna processingGO:0006396220.017
rna splicing via transesterification reactionsGO:000037570.017
response to decreased oxygen levelsGO:00362932370.017
protein complex assemblyGO:00064612630.017
Human
cytoplasmic transportGO:00164821150.017
Human
protein complex biogenesisGO:00702712630.017
Human
dna integrity checkpointGO:003157020.017
embryonic pattern specificationGO:000988010.017
amine metabolic processGO:0009308380.017
viral gene expressionGO:001908020.017
microtubule cytoskeleton organizationGO:0000226250.017
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243630.017
positive regulation of cellular component organizationGO:00511302000.017
positive regulation of cellular protein metabolic processGO:00322701670.017
positive regulation of cell developmentGO:00107201760.016
cellular response to stressGO:00335542690.016
Human
response to oxygen levelsGO:00704822650.016
regulation of system processGO:00440572080.016
aromatic compound catabolic processGO:00194391680.016
neural crest cell differentiationGO:001403320.015
meiotic cell cycle processGO:190304630.015
positive regulation of protein modification processGO:00314011420.015
response to monosaccharideGO:00342841590.015
regulation of phosphorylationGO:00423252480.015
axon developmentGO:0061564960.015
Fly
regulation of meiotic cell cycleGO:005144530.015
cellular process involved in reproduction in multicellular organismGO:0022412350.015
positive regulation of developmental processGO:00510942830.015
heart developmentGO:0007507720.015
regulation of phosphate metabolic processGO:00192203490.015
regulation of reactive oxygen species biosynthetic processGO:190342650.015
regulation of smooth muscle cell proliferationGO:0048660750.015
rna catabolic processGO:000640130.015
positive regulation of mrna metabolic processGO:190331340.015
regulation of locomotionGO:00400121480.015
localization of cellGO:00516742020.015
microtubule based processGO:0007017360.015
ribonucleoprotein complex biogenesisGO:0022613100.014
g protein coupled receptor signaling pathwayGO:00071862420.014
protein oligomerizationGO:00512591910.014
Human
response to peptideGO:19016522920.014
Rat
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.014
response to hydrogen peroxideGO:0042542890.014
carbohydrate biosynthetic processGO:0016051420.014
nuclear transportGO:0051169490.014
Human
rna localizationGO:000640340.014
negative regulation of apoptotic processGO:00430661810.014
chromatin disassemblyGO:003149810.014
reproductive structure developmentGO:00486081280.014
Mouse
negative regulation of protein metabolic processGO:00512481140.014
cellular carbohydrate metabolic processGO:0044262720.014
cytosolic calcium ion homeostasisGO:00514801400.014
nucleosome disassemblyGO:000633710.014
protein modification by small protein conjugationGO:0032446310.014
Human
heterocycle catabolic processGO:00467001670.013
organic hydroxy compound transportGO:0015850770.013
cellular homeostasisGO:00197252520.013
negative regulation of cellular component organizationGO:0051129830.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
organic substance catabolic processGO:19015753160.013
cellular lipid metabolic processGO:00442552080.013
regulation of programmed cell deathGO:00430673410.013
regulation of cellular catabolic processGO:00313291010.013
covalent chromatin modificationGO:0016569300.013
organic acid metabolic processGO:00060822920.013
cellular response to peptideGO:19016531330.013
response to lipopolysaccharideGO:00324961910.013
positive regulation of phosphorylationGO:00423271770.013
regulation of apoptotic processGO:00429813350.013
dna modificationGO:0006304120.013
Mouse
response to ionizing radiationGO:0010212590.013
multicellular organismal signalingGO:0035637440.013
negative regulation of vasculature developmentGO:1901343110.013
positive regulation of nitric oxide biosynthetic processGO:0045429140.012
head developmentGO:00603222470.012
nucleobase containing compound catabolic processGO:00346551520.012
negative regulation of programmed cell deathGO:00430691830.012
multicellular organism growthGO:003526410.012
g protein coupled receptor internalizationGO:000203130.012
mrna 3 end processingGO:003112410.012
axonogenesisGO:0007409710.012
Fly
cellular catabolic processGO:00442482950.012
positive regulation of transferase activityGO:0051347810.012
regulation of cell fate commitmentGO:001045310.012
molting cycle processGO:002240420.012
positive regulation of response to stimulusGO:00485842850.012
Human
negative regulation of cell cycle phase transitionGO:190198840.012
catecholamine transportGO:0051937370.012
positive regulation of signal transductionGO:00099671750.012
fertilizationGO:000956630.012
blood vessel developmentGO:0001568690.012
positive regulation of protein phosphorylationGO:00019341350.012
cellular response to external stimulusGO:00714961180.012
forebrain developmentGO:0030900980.012
cellular response to endogenous stimulusGO:00714953770.012
cellular amide metabolic processGO:0043603440.011
regulation of cellular amine metabolic processGO:003323880.011
polysaccharide metabolic processGO:0005976250.011
negative regulation of ion transmembrane transporter activityGO:0032413120.011
cell morphogenesisGO:00009021420.011
Mouse Fly
positive regulation of molecular functionGO:00440932300.011
reactive nitrogen species metabolic processGO:200105710.011
regulation of cell migrationGO:00303341280.011
response to tumor necrosis factorGO:0034612560.011
nucleotide metabolic processGO:00091172790.011
positive regulation of fat cell differentiationGO:004560020.011
response to carbohydrateGO:00097431830.011
positive regulation of proteasomal protein catabolic processGO:190180030.011
sensory organ developmentGO:0007423740.011
cellular response to cytokine stimulusGO:00713451270.011
growthGO:00400071650.011
Mouse
response to transforming growth factor betaGO:0071559460.011
insulin like growth factor receptor signaling pathwayGO:004800930.011
catecholamine secretionGO:0050432330.011
response to hyperoxiaGO:0055093450.011
reactive oxygen species biosynthetic processGO:190340980.011
positive regulation of cellular amino acid metabolic processGO:004576410.010
response to nutrientGO:00075842480.010
response to peptide hormoneGO:00434342780.010
Rat
response to ethanolGO:00454711620.010
positive regulation of neurogenesisGO:00507691650.010
cellular response to lipidGO:00713962010.010
hair cycle processGO:002240520.010
embryonic skeletal system developmentGO:004870630.010
ribonucleoprotein complex assemblyGO:002261880.010
macromolecule methylationGO:0043414160.010
Mouse
embryonic hindlimb morphogenesisGO:003511620.010
response to hypoxiaGO:00016662310.010
chemosensory behaviorGO:000763520.010
response to molecule of bacterial originGO:00022371940.010
regulation of response to external stimulusGO:00321011060.010

Trim28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hepatocellular carcinomaDOID:68400.021
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
liver carcinomaDOID:68600.021
gastrointestinal system cancerDOID:311900.021
liver cancerDOID:357100.021
organ system cancerDOID:005068600.021
musculoskeletal system diseaseDOID:1700.016
cardiovascular system diseaseDOID:128700.016
heart diseaseDOID:11400.016
cardiomyopathyDOID:005070000.016
muscular diseaseDOID:008000000.016
intrinsic cardiomyopathyDOID:006003600.016
dilated cardiomyopathyDOID:1293000.016
myopathyDOID:42300.016
disease of anatomical entityDOID:700.016
muscle tissue diseaseDOID:6600.016