Rattus norvegicus

0 known processes

Trim21

tripartite motif-containing 21

Trim21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.102
Human
protein complex assemblyGO:00064612630.063
Human
defense responseGO:00069521940.061
Human
response to oxidative stressGO:00069791860.060
rna biosynthetic processGO:00327743800.059
Human
macromolecular complex assemblyGO:00650032730.058
Human
response to extracellular stimulusGO:00099913800.049
macromolecular complex subunit organizationGO:00439333390.046
Human
regulation of rna metabolic processGO:00512523910.044
Human
cellular component biogenesisGO:00440853680.044
Human
regulation of molecular functionGO:00650093980.044
Human
response to woundingGO:00096112540.043
amine metabolic processGO:0009308380.043
homeostatic processGO:00425923310.041
regulation of nucleic acid templated transcriptionGO:19035063800.040
Human
negative regulation of cellular metabolic processGO:00313242810.039
Human
immune system processGO:00023762040.039
Human
cell cell signalingGO:00072673350.039
positive regulation of nitrogen compound metabolic processGO:00511733340.038
transcription dna templatedGO:00063513770.038
Human
protein complex biogenesisGO:00702712630.038
Human
positive regulation of biosynthetic processGO:00098913190.037
protein complex subunit organizationGO:00718223020.037
Human
chemical homeostasisGO:00488782920.037
programmed cell deathGO:00125013920.034
positive regulation of gene expressionGO:00106282440.034
negative regulation of macromolecule metabolic processGO:00106052600.032
Human
cation homeostasisGO:00550801950.032
response to inorganic substanceGO:00100353770.032
positive regulation of response to stimulusGO:00485842850.032
cell projection organizationGO:00300303020.031
multicellular organism reproductionGO:00325042330.031
negative regulation of metabolic processGO:00098923310.031
Human
protein oligomerizationGO:00512591910.031
Human
positive regulation of molecular functionGO:00440932300.030
Human
cellular component movementGO:00069282480.030
positive regulation of developmental processGO:00510942830.030
response to external biotic stimulusGO:00432072210.030
calcium ion homeostasisGO:00550741620.030
intracellular signal transductionGO:00355563140.029
cellular component assemblyGO:00226073600.029
Human
reproductive processGO:00224143720.029
regulation of protein metabolic processGO:00512462890.029
Human
multi organism reproductive processGO:00447032620.029
organic cyclic compound catabolic processGO:19013611750.028
ion homeostasisGO:00508012120.028
regulation of cell differentiationGO:00455953200.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
nucleoside phosphate metabolic processGO:00067532830.027
tissue developmentGO:00098882520.027
cellular amine metabolic processGO:0044106380.027
synaptic transmissionGO:00072682350.026
positive regulation of multicellular organismal processGO:00512403870.026
apoptotic processGO:00069153810.026
negative regulation of cellular biosynthetic processGO:00313271610.026
Human
positive regulation of secretionGO:00510471400.026
regulation of programmed cell deathGO:00430673410.026
regulation of catalytic activityGO:00507903040.026
regulation of hydrolase activityGO:00513361430.026
nitrogen compound transportGO:00717052290.026
localization of cellGO:00516742020.025
cellular response to endogenous stimulusGO:00714953770.025
muscle system processGO:00030121150.025
negative regulation of macromolecule biosynthetic processGO:00105581480.025
Human
positive regulation of signalingGO:00230562700.025
single organism reproductive processGO:00447022970.025
regulation of rna biosynthetic processGO:20011413810.025
Human
neuron differentiationGO:00301823680.025
reproductionGO:00000032450.025
neurological system processGO:00508772190.025
regulation of immune system processGO:00026821230.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
positive regulation of cellular biosynthetic processGO:00313282950.025
anatomical structure morphogenesisGO:00096532980.025
regulation of transcription dna templatedGO:00063553740.025
Human
leukocyte activationGO:0045321760.025
response to estrogenGO:00436272320.025
metal ion homeostasisGO:00550651860.025
regulation of body fluid levelsGO:0050878900.024
regulation of cellular amino acid metabolic processGO:000652120.024
organelle organizationGO:00069962660.024
cell activationGO:0001775970.024
cellular chemical homeostasisGO:00550822470.024
regulation of anatomical structure sizeGO:00900661350.024
cell migrationGO:00164771970.024
nucleic acid templated transcriptionGO:00976593790.023
Human
transmembrane transportGO:00550854120.023
sexual reproductionGO:00199531480.023
circulatory system processGO:00030131830.023
negative regulation of nitrogen compound metabolic processGO:00511721610.023
Human
multicellular organismal reproductive processGO:00486092330.023
negative regulation of gene expressionGO:00106291990.023
Human
response to peptide hormoneGO:00434342780.023
negative regulation of response to stimulusGO:00485851550.023
vesicle mediated transportGO:00161921810.023
regulation of response to external stimulusGO:00321011060.022
response to nutrient levelsGO:00316673700.022
positive regulation of cell proliferationGO:00082842490.022
response to corticosteroidGO:00319602350.021
agingGO:00075682410.021
response to nutrientGO:00075842480.021
developmental process involved in reproductionGO:00030061590.021
positive regulation of signal transductionGO:00099671750.021
regulation of signal transductionGO:00099663180.021
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
Human
cellular cation homeostasisGO:00300031800.021
regulation of cellular amine metabolic processGO:003323880.021
reproductive system developmentGO:00614581280.020
regulation of apoptotic processGO:00429813350.020
cellular calcium ion homeostasisGO:00068741600.020
immune effector processGO:0002252530.020
blood circulationGO:00080151830.020
response to monosaccharideGO:00342841590.020
central nervous system developmentGO:00074173110.020
catabolic processGO:00090563510.020
cellular response to stressGO:00335542690.020
organic acid metabolic processGO:00060822920.020
secretionGO:00469033070.019
regulation of cellular ketone metabolic processGO:0010565270.019
regulation of behaviorGO:0050795610.019
immune responseGO:00069551040.019
Human
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.019
positive regulation of catalytic activityGO:00430851840.019
regulation of multicellular organismal developmentGO:20000263760.019
response to oxygen levelsGO:00704822650.019
regulation of system processGO:00440572080.019
response to reactive oxygen speciesGO:00003021200.019
negative regulation of natural killer cell mediated immunityGO:000271640.019
response to temperature stimulusGO:0009266940.019
organophosphate metabolic processGO:00196373700.019
response to ketoneGO:19016541820.019
positive regulation of cell migrationGO:0030335960.019
cellular ion homeostasisGO:00068731840.019
positive regulation of cellular component movementGO:00512721020.019
carbohydrate metabolic processGO:00059751300.019
cytosolic calcium ion homeostasisGO:00514801400.019
inflammatory responseGO:00069541500.019
chemosensory behaviorGO:000763520.019
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.019
positive regulation of phosphate metabolic processGO:00459372620.019
nucleobase containing compound catabolic processGO:00346551520.018
secretion by cellGO:00329402480.018
cellular response to oxygen containing compoundGO:19017013860.018
neuron developmentGO:00486662860.018
appendage morphogenesisGO:003510740.018
proteolysisGO:00065081750.018
positive regulation of transcription dna templatedGO:00458931970.018
metal ion transportGO:00300012890.018
ribose phosphate metabolic processGO:00196932350.018
cellular metal ion homeostasisGO:00068751720.018
heart morphogenesisGO:000300730.018
regulation of response to stressGO:00801341260.018
cellular response to external stimulusGO:00714961180.018
response to metal ionGO:00100382530.018
response to acid chemicalGO:00011012220.017
regulation of intracellular signal transductionGO:19025312180.017
wound healingGO:00420601220.017
response to estradiolGO:00323551640.017
regulation of phosphorus metabolic processGO:00511743490.017
behaviorGO:00076102050.017
aromatic compound catabolic processGO:00194391680.017
regulation of catabolic processGO:00098941130.017
regulation of organelle organizationGO:0033043800.017
regulation of membrane potentialGO:00423911100.017
protein phosphorylationGO:00064683450.017
hormone secretionGO:00468791150.017
single organism carbohydrate metabolic processGO:00447231180.017
hormone transportGO:00099141210.017
regulation of phosphate metabolic processGO:00192203490.017
cellular response to organonitrogen compoundGO:00714171970.017
positive regulation of rna metabolic processGO:00512542030.017
organonitrogen compound catabolic processGO:19015651790.017
response to peptideGO:19016522920.016
regulation of cellular protein metabolic processGO:00322682670.016
Human
response to decreased oxygen levelsGO:00362932370.016
limb morphogenesisGO:003510840.016
cellular response to abiotic stimulusGO:0071214850.016
transcription from rna polymerase ii promoterGO:00063662520.016
regulation of defense responseGO:0031347680.016
organic substance catabolic processGO:19015753160.016
regulation of cellular component organizationGO:00511283680.016
negative regulation of multicellular organismal processGO:00512412030.016
carboxylic acid metabolic processGO:00197522890.016
actin filament based processGO:0030029860.016
dephosphorylationGO:0016311980.016
single organism biosynthetic processGO:00447113420.016
mesoderm developmentGO:000749820.016
positive regulation of cell motilityGO:2000147970.016
nucleotide metabolic processGO:00091172790.016
heterocycle catabolic processGO:00467001670.016
response to ethanolGO:00454711620.016
female pregnancyGO:00075651220.016
response to mechanical stimulusGO:00096121340.016
calcium ion transportGO:00068161310.016
neuron projection developmentGO:00311752730.016
positive regulation of immune system processGO:0002684900.016
oxoacid metabolic processGO:00434362900.016
regulation of secretion by cellGO:19035302080.016
negative regulation of transcription dna templatedGO:00458921160.016
negative regulation of innate immune responseGO:004582440.016
cellular nitrogen compound catabolic processGO:00442701630.016
response to hexoseGO:00097461440.016
divalent inorganic cation homeostasisGO:00725071650.016
reproductive structure developmentGO:00486081280.016
peptide secretionGO:0002790860.015
negative regulation of biosynthetic processGO:00098901680.015
Human
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
positive regulation of cellular amine metabolic processGO:003324030.015
regulation of peptide transportGO:0090087870.015
regenerationGO:00310991630.015
regulation of cell developmentGO:00602842630.015
positive regulation of cellular component organizationGO:00511302000.015
intracellular transportGO:00469071850.015
single organism intracellular transportGO:19025821660.015
multicellular organismal signalingGO:0035637440.015
regulation of peptide secretionGO:0002791820.015
positive regulation of map kinase activityGO:0043406460.015
response to toxic substanceGO:00096361330.015
anterior posterior pattern specificationGO:000995210.015
nucleoside metabolic processGO:00091161790.015
vascular process in circulatory systemGO:0003018960.015
response to hydrogen peroxideGO:0042542890.015
positive regulation of transportGO:00510502450.015
regulation of cell migrationGO:00303341280.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
response to hypoxiaGO:00016662310.015
regulation of hormone levelsGO:00108171870.014
cellular amino acid metabolic processGO:00065201070.014
single organism organelle organizationGO:19025891800.014
locomotionGO:00400112370.014
adult locomotory behaviorGO:000834440.014
negative regulation of apoptotic processGO:00430661810.014
cellular response to nitrogen compoundGO:19016992100.014
single organism behaviorGO:00447081300.014
protein localizationGO:00081041910.014
regulation of response to woundingGO:1903034690.014
cellular ketone metabolic processGO:0042180510.014
purine ribonucleotide metabolic processGO:00091502270.014
response to biotic stimulusGO:00096072260.014
negative regulation of rna metabolic processGO:00512531230.014
Human
positive regulation of nervous system developmentGO:00519621780.014
small gtpase mediated signal transductionGO:0007264360.014
divalent inorganic cation transportGO:00725111340.014
response to growth factorGO:00708481890.014
positive regulation of phosphorus metabolic processGO:00105622620.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
positive regulation of apoptotic processGO:00430651540.014
macromolecule localizationGO:00330362520.014
cellular catabolic processGO:00442482950.014
negative regulation of cell communicationGO:00106481580.014
negative regulation of cell deathGO:00605482290.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
rhythmic processGO:00485111560.013
positive regulation of cell communicationGO:00106472710.013
cell motilityGO:00488702020.013
sex differentiationGO:00075481130.013
olfactory behaviorGO:004204820.013
peptide transportGO:0015833970.013
regulation of cell projection organizationGO:00313441750.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
positive regulation of cell differentiationGO:00455972170.013
regulation of secretionGO:00510462240.013
positive regulation of intracellular signal transductionGO:19025331380.013
negative regulation of developmental processGO:00510931250.013
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.013
cellular homeostasisGO:00197252520.013
response to other organismGO:00517072200.013
reactive oxygen species metabolic processGO:0072593370.013
single organism cell adhesionGO:0098602460.013
carbohydrate derivative metabolic processGO:19011353460.013
regulation of peptide hormone secretionGO:0090276800.013
response to carbohydrateGO:00097431830.013
purine nucleotide metabolic processGO:00061632290.013
regulation of cellular catabolic processGO:00313291010.013
defense response to gram positive bacteriumGO:005083020.013
monovalent inorganic cation transportGO:00156721720.013
head developmentGO:00603222470.013
regulation of metal ion transportGO:00109591180.013
gland developmentGO:00487321550.013
organ morphogenesisGO:0009887750.013
regulation of locomotionGO:00400121480.013
cellular response to organic cyclic compoundGO:00714072020.013
female gonad developmentGO:0008585530.012
regulation of neurogenesisGO:00507672470.012
positive regulation of cell developmentGO:00107201760.012
negative regulation of cellular component organizationGO:0051129830.012
regulation of cell motilityGO:20001451310.012
response to glucoseGO:00097491360.012
development of primary female sexual characteristicsGO:0046545560.012
signal releaseGO:00230611450.012
positive regulation of rna biosynthetic processGO:19026801970.012
reactive oxygen species biosynthetic processGO:190340980.012
positive regulation of defense responseGO:0031349370.012
glycosyl compound catabolic processGO:19016581260.012
cell adhesionGO:00071551100.012
purine containing compound metabolic processGO:00725212530.012
cellular response to lipidGO:00713962010.012
glycosyl compound metabolic processGO:19016571820.012
muscle cell proliferationGO:0033002840.012
positive regulation of hydrolase activityGO:0051345860.012
positive regulation of mapk cascadeGO:0043410920.012
positive regulation of immune responseGO:0050778420.012
ras protein signal transductionGO:0007265290.012
leukocyte cell cell adhesionGO:000715940.012
regulation of blood circulationGO:19035221100.012
purine containing compound catabolic processGO:00725231380.012
response to progesteroneGO:0032570480.012
ribonucleotide metabolic processGO:00092592310.012
reactive nitrogen species metabolic processGO:200105710.011
nucleobase containing small molecule metabolic processGO:00550863160.011
positive regulation of programmed cell deathGO:00430681570.011
embryonic limb morphogenesisGO:003032640.011
cytoskeleton organizationGO:00070101110.011
positive regulation of phosphorylationGO:00423271770.011
action potentialGO:0001508540.011
cellular response to cytokine stimulusGO:00713451270.011
positive regulation of response to external stimulusGO:0032103510.011
regulation of stem cell differentiationGO:200073620.011
positive regulation of protein phosphorylationGO:00019341350.011
peptide hormone secretionGO:0030072840.011
response to transition metal nanoparticleGO:19902671220.011
axis specificationGO:000979840.011
gonad developmentGO:00084061040.011
regulation of hormone secretionGO:00468831060.011
cardiac conductionGO:006133720.011
response to bacteriumGO:00096172000.011
divalent metal ion transportGO:00708381320.011
amide transportGO:00428861050.011
peptidyl amino acid modificationGO:00181931260.011
response to cytokineGO:00340972150.011
salivary gland morphogenesisGO:000743510.011
response to glucocorticoidGO:00513842230.011
regulation of inflammatory responseGO:0050727480.011
nucleotide catabolic processGO:00091661390.011
regulation of vesicle mediated transportGO:0060627810.011
regulation of cellular component movementGO:00512701500.011
cell part morphogenesisGO:00329901230.011
regulation of blood vessel sizeGO:0050880890.011
cation transportGO:00068123820.011
regulation of map kinase activityGO:0043405530.011
negative regulation of cell differentiationGO:0045596990.011
positive regulation of cell projection organizationGO:00313461110.011
regulation of nervous system developmentGO:00519602640.011
female sex differentiationGO:0046660590.011
embryonic appendage morphogenesisGO:003511340.011
sequestering of metal ionGO:005123890.011
gastrulationGO:000736920.010
defense response to gram negative bacteriumGO:005082930.010
positive regulation of cell deathGO:00109421840.010
regulation of leukocyte activationGO:0002694450.010
cellular response to growth factor stimulusGO:00713631620.010
cellular response to alcoholGO:0097306870.010
regulation of canonical wnt signaling pathwayGO:006082840.010
regulation of phosphorylationGO:00423252480.010
biological adhesionGO:00226101100.010
cell cycleGO:00070491010.010
Human
negative regulation of programmed cell deathGO:00430691830.010
vasculature developmentGO:0001944700.010
regulation of cell proliferationGO:00421273590.010
signal transduction by phosphorylationGO:00230141440.010
salivary gland developmentGO:000743130.010
regulation of insulin secretionGO:0050796650.010
positive regulation of neuron differentiationGO:00456661260.010
purine ribonucleoside metabolic processGO:00461281680.010
male gamete generationGO:0048232990.010
neuronal action potentialGO:0019228350.010
regulation of anatomical structure morphogenesisGO:00226031410.010
response to amino acidGO:0043200750.010

Trim21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.018
musculoskeletal system diseaseDOID:1700.016
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.014
muscular diseaseDOID:008000000.013
myopathyDOID:42300.013
muscle tissue diseaseDOID:6600.013
sensory system diseaseDOID:005015500.012
inherited metabolic disorderDOID:65500.011