Rattus norvegicus

96 known processes

Itpka

inositol 1,4,5-trisphosphate 3-kinase A

Itpka biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.378
response to nutrient levelsGO:00316673700.281
organic substance catabolic processGO:19015753160.226
catabolic processGO:00090563510.203
positive regulation of nitrogen compound metabolic processGO:00511733340.199
oxoacid metabolic processGO:00434362900.159
response to toxic substanceGO:00096361330.153
positive regulation of nucleobase containing compound metabolic processGO:00459353190.152
apoptotic processGO:00069153810.150
response to extracellular stimulusGO:00099913800.148
positive regulation of biosynthetic processGO:00098913190.124
organic acid metabolic processGO:00060822920.121
synaptic transmissionGO:00072682350.119
single organism catabolic processGO:00447122830.108
vesicle mediated transportGO:00161921810.107
regulation of intracellular signal transductionGO:19025312180.099
regulation of phosphate metabolic processGO:00192203490.097
glycerolipid metabolic processGO:0046486670.097
regulation of signal transductionGO:00099663180.087
response to external biotic stimulusGO:00432072210.086
cellular amino acid metabolic processGO:00065201070.083
heterocycle catabolic processGO:00467001670.081
regulation of multicellular organismal developmentGO:20000263760.081
aromatic compound catabolic processGO:00194391680.080
regulation of phosphorus metabolic processGO:00511743490.080
response to oxidative stressGO:00069791860.079
Fly
purine nucleotide metabolic processGO:00061632290.078
regulation of molecular functionGO:00650093980.078
neuron deathGO:00709971270.075
regulation of hydrolase activityGO:00513361430.071
oxidation reduction processGO:00551143040.070
positive regulation of cellular biosynthetic processGO:00313282950.069
response to biotic stimulusGO:00096072260.068
macromolecular complex subunit organizationGO:00439333390.066
regulation of catalytic activityGO:00507903040.065
purine containing compound catabolic processGO:00725231380.065
cellular component biogenesisGO:00440853680.063
ribonucleoside triphosphate metabolic processGO:00091991410.062
rhythmic processGO:00485111560.061
nucleoside triphosphate metabolic processGO:00091411440.060
agingGO:00075682410.060
ion transmembrane transportGO:00342203650.059
positive regulation of macromolecule biosynthetic processGO:00105572470.058
response to decreased oxygen levelsGO:00362932370.056
gtp catabolic processGO:0006184710.056
response to hypoxiaGO:00016662310.055
nucleic acid templated transcriptionGO:00976593790.054
transcription dna templatedGO:00063513770.053
protein localizationGO:00081041910.053
protein complex subunit organizationGO:00718223020.053
cellular nitrogen compound catabolic processGO:00442701630.052
regulation of cellular catabolic processGO:00313291010.051
nucleoside phosphate metabolic processGO:00067532830.051
positive regulation of molecular functionGO:00440932300.051
gtp metabolic processGO:0046039720.051
rna metabolic processGO:00160704060.050
cellular catabolic processGO:00442482950.050
carbohydrate derivative catabolic processGO:19011361470.050
cellular response to hormone stimulusGO:00328702470.049
response to nutrientGO:00075842480.049
regulation of system processGO:00440572080.048
regulation of protein modification processGO:00313991940.048
cellular response to nitrogen compoundGO:19016992100.048
head developmentGO:00603222470.048
endocytosisGO:0006897840.048
organophosphate metabolic processGO:00196373700.047
Fly
nucleoside catabolic processGO:00091641260.047
purine nucleoside triphosphate catabolic processGO:00091461220.047
response to insulinGO:00328681330.047
amine metabolic processGO:0009308380.047
protein heterooligomerizationGO:0051291890.047
organonitrogen compound catabolic processGO:19015651790.046
growthGO:00400071650.046
cellular response to peptideGO:19016531330.046
positive regulation of transportGO:00510502450.046
response to estrogenGO:00436272320.046
cellular homeostasisGO:00197252520.046
regulation of cellular amino acid metabolic processGO:000652120.045
rna biosynthetic processGO:00327743800.045
inorganic cation transmembrane transportGO:00986622020.044
response to acid chemicalGO:00011012220.044
nucleobase containing compound catabolic processGO:00346551520.044
positive regulation of phosphorus metabolic processGO:00105622620.044
peptidyl amino acid modificationGO:00181931260.044
nucleoside triphosphate catabolic processGO:00091431230.043
cell cell signalingGO:00072673350.043
cellular component assemblyGO:00226073600.043
regulation of synaptic transmissionGO:00508041410.043
transmembrane transportGO:00550854120.042
purine ribonucleotide catabolic processGO:00091541360.042
protein complex assemblyGO:00064612630.042
neuron differentiationGO:00301823680.042
guanosine containing compound catabolic processGO:1901069710.042
positive regulation of apoptotic processGO:00430651540.041
macromolecular complex assemblyGO:00650032730.041
inorganic ion transmembrane transportGO:00986602290.041
nucleotide catabolic processGO:00091661390.040
regulation of nucleic acid templated transcriptionGO:19035063800.040
single organism biosynthetic processGO:00447113420.039
Fly
response to lipopolysaccharideGO:00324961910.039
multicellular organism growthGO:003526410.039
nucleotide metabolic processGO:00091172790.039
metal ion transportGO:00300012890.039
protein oligomerizationGO:00512591910.039
positive regulation of catalytic activityGO:00430851840.039
cellular amine metabolic processGO:0044106380.039
response to woundingGO:00096112540.039
response to ethanolGO:00454711620.038
neuron apoptotic processGO:0051402880.038
response to amino acidGO:0043200750.037
reproductive processGO:00224143720.037
positive regulation of signal transductionGO:00099671750.037
phospholipid metabolic processGO:0006644610.036
developmental process involved in reproductionGO:00030061590.036
positive regulation of intracellular signal transductionGO:19025331380.036
response to estradiolGO:00323551640.036
cellular response to organic cyclic compoundGO:00714072020.036
negative regulation of cell deathGO:00605482290.035
small gtpase mediated signal transductionGO:0007264360.035
purine ribonucleoside catabolic processGO:00461301240.035
positive regulation of protein metabolic processGO:00512471780.035
regulation of nucleoside metabolic processGO:0009118660.035
regulation of apoptotic processGO:00429813350.035
organophosphate catabolic processGO:00464341480.034
purine nucleoside metabolic processGO:00422781690.034
response to oxygen levelsGO:00704822650.034
ribose phosphate metabolic processGO:00196932350.034
purine ribonucleoside triphosphate metabolic processGO:00092051400.033
somatostatin signaling pathwayGO:003817040.033
purine containing compound metabolic processGO:00725212530.033
chemical homeostasisGO:00488782920.033
nucleoside metabolic processGO:00091161790.033
positive regulation of cell deathGO:00109421840.033
regulation of cellular amine metabolic processGO:003323880.033
cellular response to oxygen containing compoundGO:19017013860.032
response to peptideGO:19016522920.032
response to inorganic substanceGO:00100353770.032
l glutamate importGO:005193820.031
nucleoside phosphate catabolic processGO:19012921400.031
reproductionGO:00000032450.031
positive regulation of phosphate metabolic processGO:00459372620.030
response to vitaminGO:00332731310.030
response to carbohydrateGO:00097431830.030
guanosine containing compound metabolic processGO:1901068740.030
regulation of programmed cell deathGO:00430673410.030
defense responseGO:00069521940.030
regulation of purine nucleotide metabolic processGO:19005421150.030
ribonucleoside metabolic processGO:00091191740.030
homeostatic processGO:00425923310.030
regulation of vesicle mediated transportGO:0060627810.030
intracellular signal transductionGO:00355563140.030
negative regulation of metabolic processGO:00098923310.030
ribonucleotide metabolic processGO:00092592310.030
regulation of protein metabolic processGO:00512462890.029
response to other organismGO:00517072200.029
regulation of rna metabolic processGO:00512523910.029
regulation of cellular protein metabolic processGO:00322682670.029
organic cyclic compound catabolic processGO:19013611750.029
single organism reproductive processGO:00447022970.029
response to hydrogen peroxideGO:0042542890.028
response to molecule of bacterial originGO:00022371940.028
organelle organizationGO:00069962660.028
response to starvationGO:0042594590.028
negative regulation of cellular metabolic processGO:00313242810.028
circulatory system processGO:00030131830.027
regulation of membrane potentialGO:00423911100.027
programmed cell deathGO:00125013920.027
positive regulation of multicellular organismal processGO:00512403870.027
glutamate receptor signaling pathwayGO:0007215430.027
cation transportGO:00068123820.027
regulation of catabolic processGO:00098941130.026
organonitrogen compound biosynthetic processGO:19015661670.026
multicellular organism reproductionGO:00325042330.026
cellular response to stressGO:00335542690.026
regulation of nucleotide metabolic processGO:00061401170.026
protein autophosphorylationGO:0046777660.026
cellular response to endogenous stimulusGO:00714953770.026
purine ribonucleoside metabolic processGO:00461281680.025
response to peptide hormoneGO:00434342780.025
response to glucocorticoidGO:00513842230.025
ribonucleoside catabolic processGO:00424541260.025
response to ketoneGO:19016541820.025
lipid metabolic processGO:00066292830.025
regulation of blood circulationGO:19035221100.024
cellular glucan metabolic processGO:0006073230.024
ras protein signal transductionGO:0007265290.024
protein complex biogenesisGO:00702712630.024
regulation of neuron apoptotic processGO:0043523830.024
regulation of rna biosynthetic processGO:20011413810.024
response to monosaccharideGO:00342841590.024
single organism organelle organizationGO:19025891800.024
cellular response to organonitrogen compoundGO:00714171970.024
transcription from rna polymerase ii promoterGO:00063662520.023
intracellular transportGO:00469071850.023
regulation of cellular component organizationGO:00511283680.023
regulation of transporter activityGO:0032409500.023
positive regulation of response to stimulusGO:00485842850.023
multicellular organismal reproductive processGO:00486092330.023
cellular response to peptide hormone stimulusGO:00713751200.023
ribonucleotide catabolic processGO:00092611360.023
regulation of cellular ketone metabolic processGO:0010565270.023
alpha amino acid biosynthetic processGO:1901607230.023
regulation of neuron projection developmentGO:00109751610.023
cellular ketone metabolic processGO:0042180510.023
purine ribonucleotide metabolic processGO:00091502270.023
locomotionGO:00400112370.023
response to foodGO:0032094270.023
positive regulation of purine nucleotide metabolic processGO:1900544910.023
nucleobase containing small molecule metabolic processGO:00550863160.022
purine nucleotide catabolic processGO:00061951360.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
ionotropic glutamate receptor signaling pathwayGO:0035235340.022
proteolysisGO:00065081750.022
positive regulation of transcription dna templatedGO:00458931970.022
purine nucleoside triphosphate metabolic processGO:00091441410.022
blood circulationGO:00080151830.022
positive regulation of rna metabolic processGO:00512542030.022
brain developmentGO:00074202470.021
regulation of sodium ion transmembrane transporter activityGO:200064940.021
neuron developmentGO:00486662860.021
positive regulation of cellular amine metabolic processGO:003324030.021
dendritic spine morphogenesisGO:006099790.021
response to transition metal nanoparticleGO:19902671220.021
negative regulation of macromolecule metabolic processGO:00106052600.021
positive regulation of programmed cell deathGO:00430681570.021
purine ribonucleoside triphosphate catabolic processGO:00092071220.021
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
regulation of phosphorylationGO:00423252480.020
cytoskeleton organizationGO:00070101110.020
secretionGO:00469033070.020
regulation of endocytosisGO:0030100420.020
glycosyl compound metabolic processGO:19016571820.020
behaviorGO:00076102050.020
regulation of growthGO:00400081050.020
female sex differentiationGO:0046660590.020
regulation of tube sizeGO:0035150890.020
protein transportGO:00150311320.020
glycerophospholipid metabolic processGO:0006650470.020
regulation of excitatory postsynaptic membrane potentialGO:0060079180.020
negative regulation of apoptotic processGO:00430661810.019
positive regulation of gtp catabolic processGO:0033126480.019
cell type specific apoptotic processGO:00972851340.019
response to ammonium ionGO:0060359710.019
regulation of gtpase activityGO:0043087570.019
wound healingGO:00420601220.019
generation of precursor metabolites and energyGO:0006091620.019
ion homeostasisGO:00508012120.019
response to cytokineGO:00340972150.019
carbohydrate derivative metabolic processGO:19011353460.019
organophosphate biosynthetic processGO:00904071430.019
Fly
positive regulation of cellular amino acid metabolic processGO:004576410.019
cardiac muscle cell contractionGO:0086003100.019
regulation of transcription dna templatedGO:00063553740.018
response to hexoseGO:00097461440.018
positive regulation of hydrolase activityGO:0051345860.018
response to bacteriumGO:00096172000.018
multi organism reproductive processGO:00447032620.018
cation transmembrane transportGO:00986552630.018
bmp signaling pathwayGO:003050940.018
respiratory gaseous exchangeGO:000758540.018
neurological system processGO:00508772190.018
enzyme linked receptor protein signaling pathwayGO:00071671160.018
sex differentiationGO:00075481130.018
gastrulationGO:000736920.018
positive regulation of purine nucleotide catabolic processGO:0033123530.018
synaptic growth at neuromuscular junctionGO:005112410.018
regulation of homeostatic processGO:00328441010.017
regulation of anatomical structure sizeGO:00900661350.017
embryo developmentGO:0009790490.017
protein phosphorylationGO:00064683450.017
single organism behaviorGO:00447081300.017
regulation of transcription from rna polymerase ii promoterGO:00063572340.017
smooth muscle cell proliferationGO:0048659770.017
sodium ion transportGO:0006814820.017
positive regulation of nucleoside metabolic processGO:0045979550.017
asymmetric protein localizationGO:000810520.017
cellular chemical homeostasisGO:00550822470.017
regulation of kinase activityGO:00435491170.017
positive regulation of rna biosynthetic processGO:19026801970.017
negative regulation of signalingGO:00230571570.016
cellular response to alcoholGO:0097306870.016
regulation of neuron deathGO:19012141150.016
positive regulation of cellular component organizationGO:00511302000.016
negative regulation of molecular functionGO:00440921330.016
regulation of protein kinase activityGO:00458591050.016
cellular response to oxidative stressGO:0034599760.016
vascular process in circulatory systemGO:0003018960.016
response to glucoseGO:00097491360.016
response to amineGO:0014075460.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
respiratory system processGO:000301630.015
positive regulation of cell communicationGO:00106472710.015
positive regulation of gtpase activityGO:0043547470.015
actin filament based processGO:0030029860.015
glycosyl compound catabolic processGO:19016581260.015
regulation of purine nucleotide catabolic processGO:0033121650.015
sensory organ developmentGO:0007423740.015
positive regulation of gene expressionGO:00106282440.015
positive regulation of protein modification processGO:00314011420.015
positive regulation of cellular catabolic processGO:0031331710.015
regulation of cell developmentGO:00602842630.015
energy reserve metabolic processGO:0006112250.015
neuron projection developmentGO:00311752730.015
negative regulation of signal transductionGO:0009968830.015
negative regulation of biosynthetic processGO:00098901680.015
positive regulation of nucleotide catabolic processGO:0030813530.015
cellular ion homeostasisGO:00068731840.015
regulation of sodium ion transportGO:0002028210.015
ovulation cycleGO:0042698670.015
cellular amino acid biosynthetic processGO:0008652320.014
regulation of protein phosphorylationGO:00019321830.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
monocarboxylic acid metabolic processGO:00327871520.014
positive regulation of neuron differentiationGO:00456661260.014
neurotransmitter uptakeGO:000150430.014
negative regulation of cell proliferationGO:00082851190.014
polysaccharide metabolic processGO:0005976250.014
regulation of ion transmembrane transportGO:00347651210.014
macromolecule catabolic processGO:0009057580.014
response to antibioticGO:0046677390.014
anion transmembrane transportGO:0098656770.014
cgmp biosynthetic processGO:0006182150.014
positive regulation of growthGO:0045927550.014
protein homooligomerizationGO:0051260910.014
regulation of cell differentiationGO:00455953200.014
membrane hyperpolarizationGO:0060081110.014
organic hydroxy compound metabolic processGO:19016151150.014
Fly
negative regulation of ion transmembrane transporter activityGO:0032413120.014
regulation of nucleotide catabolic processGO:0030811650.014
negative regulation of innate immune responseGO:004582440.013
negative regulation of cell communicationGO:00106481580.013
regulation of transmembrane transporter activityGO:0022898490.013
lipid biosynthetic processGO:00086101280.013
positive regulation of protein kinase activityGO:0045860730.013
positive regulation of signalingGO:00230562700.013
cellular component movementGO:00069282480.013
cellular protein localizationGO:00346131220.013
metal ion homeostasisGO:00550651860.013
regulation of erk1 and erk2 cascadeGO:0070372410.013
reactive nitrogen species metabolic processGO:200105710.013
regulation of small gtpase mediated signal transductionGO:0051056480.013
gamete generationGO:00072761240.013
regulation of neurogenesisGO:00507672470.013
activation of protein kinase activityGO:0032147470.013
protein localization to organelleGO:0033365570.013
cellular lipid metabolic processGO:00442552080.013
regulation of ion transmembrane transporter activityGO:0032412480.012
hepaticobiliary system developmentGO:0061008900.012
response to campGO:0051591910.012
response to corticosteroidGO:00319602350.012
negative regulation of protein metabolic processGO:00512481140.012
dephosphorylationGO:0016311980.012
cellular response to external stimulusGO:00714961180.012
positive regulation of long term synaptic potentiationGO:190027340.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
regenerationGO:00310991630.012
response to cocaineGO:0042220390.012
dna metabolic processGO:0006259960.012
sexual reproductionGO:00199531480.012
positive regulation of cellular protein metabolic processGO:00322701670.012
neurotransmitter transportGO:0006836420.012
single organism intracellular transportGO:19025821660.012
anterior posterior pattern specificationGO:000995210.012
establishment of protein localizationGO:00451841410.012
g protein coupled receptor signaling pathwayGO:00071862420.012
response to metal ionGO:00100382530.012
positive regulation of secretionGO:00510471400.012
involuntary skeletal muscle contractionGO:000301120.012
regulation of gtp catabolic processGO:0033124580.012
positive regulation of membrane potentialGO:0045838160.012
cellular response to nutrient levelsGO:0031669600.011
liver developmentGO:0001889900.011
purine containing compound biosynthetic processGO:0072522850.011
dna replicationGO:0006260370.011
divalent inorganic cation homeostasisGO:00725071650.011
regulation of mapk cascadeGO:00434081160.011
response to reactive oxygen speciesGO:00003021200.011
rho protein signal transductionGO:0007266110.011
n methyl d aspartate receptor clusteringGO:009711420.011
reactive oxygen species biosynthetic processGO:190340980.011
establishment of tissue polarityGO:000716420.011
positive regulation of cell differentiationGO:00455972170.011
development of primary female sexual characteristicsGO:0046545560.011
positive regulation of mapk cascadeGO:0043410920.011
response to purine containing compoundGO:00140741260.011
positive regulation of the force of heart contraction by epinephrineGO:000305910.011
retina morphogenesis in camera type eyeGO:006004210.011
regulation of ion transportGO:00432692450.011
response to activityGO:0014823730.011
response to mineralocorticoidGO:0051385490.011
tissue developmentGO:00098882520.011
negative regulation of cellular protein metabolic processGO:00322691060.011
cytoplasmic transportGO:00164821150.011
regulation of dna metabolic processGO:0051052600.011
somatostatin receptor signaling pathwayGO:003816940.011
cellular response to extracellular stimulusGO:0031668730.011
response to electrical stimulusGO:0051602560.011
lipid catabolic processGO:0016042460.011
glycogen metabolic processGO:0005977230.011
divalent metal ion transportGO:00708381320.011
ovulation cycle processGO:0022602500.010
negative regulation of response to stimulusGO:00485851550.010
organic anion transportGO:00157111320.010
regulation of metal ion transportGO:00109591180.010
sensory perceptionGO:00076001010.010
gonad developmentGO:00084061040.010
regulation of endopeptidase activityGO:0052548510.010
regulation of vascular smooth muscle contractionGO:000305630.010
synapse assemblyGO:0007416290.010
positive regulation of catabolic processGO:0009896780.010
regulation of blood vessel sizeGO:0050880890.010
dendritic spine developmentGO:0060996200.010
membrane depolarizationGO:0051899320.010
negative regulation of catalytic activityGO:00430861030.010
cellular response to ammonium ionGO:0071242170.010
regulation of immune system processGO:00026821230.010
adult locomotory behaviorGO:000834440.010
formation of primary germ layerGO:000170410.010
regulation of dopamine secretionGO:0014059150.010
dopamine transportGO:0015872180.010
sequestering of metal ionGO:005123890.010
negative regulation of programmed cell deathGO:00430691830.010
positive regulation of synaptic vesicle recyclingGO:190342310.010
cell morphogenesis involved in differentiationGO:00009041190.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.010

Itpka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.019
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.014
central nervous system diseaseDOID:33100.013
inherited metabolic disorderDOID:65500.013