IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Scube1

signal peptide, CUB domain, EGF-like 1

Ensembl: ENSRNOG00000010617
Entrez: 315174
RGD: 1309015
UniProtKB: F1M987

Process Predictions
Disease Predictions

Scube1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
behavior	GO:0007610	205	0.218
cation transmembrane transport	GO:0098655	263	0.191
regulation of homeostatic process	GO:0032844	101	0.115
response to estradiol	GO:0032355	164	0.089
organonitrogen compound biosynthetic process	GO:1901566	167	0.079
cation transport	GO:0006812	382	0.069
aging	GO:0007568	241	0.069
cellular amine metabolic process	GO:0044106	38	0.067
amine metabolic process	GO:0009308	38	0.059
brain development	GO:0007420	247	0.058
regulation of multicellular organismal development	GO:2000026	376	0.054
response to estrogen	GO:0043627	232	0.053
anatomical structure morphogenesis	GO:0009653	298	0.051
response to temperature stimulus	GO:0009266	94	0.050
organic anion transport	GO:0015711	132	0.050
single organism biosynthetic process	GO:0044711	342	0.045
cellular amino acid metabolic process	GO:0006520	107	0.044
regulation of apoptotic process	GO:0042981	335	0.043
chemical homeostasis	GO:0048878	292	0.042
head development	GO:0060322	247	0.040
homeostatic process	GO:0042592	331	0.040
organic acid metabolic process	GO:0006082	292	0.039
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.039
organic acid transport	GO:0015849	116	0.038
regulation of phosphate metabolic process	GO:0019220	349	0.038
vasodilation	GO:0042311	44	0.038
response to decreased oxygen levels	GO:0036293	237	0.036
regulation of protein metabolic process	GO:0051246	289	0.035
cellular protein localization	GO:0034613	122	0.034
multi organism reproductive process	GO:0044703	262	0.034
cellular chemical homeostasis	GO:0055082	247	0.033
apoptotic process	GO:0006915	381	0.033
circulatory system process	GO:0003013	183	0.033
potassium ion transport	GO:0006813	97	0.033
protein phosphorylation	GO:0006468	345	0.033
positive regulation of cell communication	GO:0010647	271	0.032
transmembrane transport	GO:0055085	412	0.032
response to oxygen levels	GO:0070482	265	0.032
cell projection organization	GO:0030030	302	0.032
positive regulation of signaling	GO:0023056	270	0.032
response to cytokine	GO:0034097	215	0.031
regulation of phosphorylation	GO:0042325	248	0.031
regulation of cellular amine metabolic process	GO:0033238	8	0.031
regulation of molecular function	GO:0065009	398	0.030
positive regulation of response to stimulus	GO:0048584	285	0.030
anion transport	GO:0006820	178	0.030
response to extracellular stimulus	GO:0009991	380	0.030
single organism reproductive process	GO:0044702	297	0.029
response to radiation	GO:0009314	137	0.029
monovalent inorganic cation transport	GO:0015672	172	0.029
neurological system process	GO:0050877	219	0.028
response to nutrient levels	GO:0031667	370	0.028
regulation of protein modification process	GO:0031399	194	0.027
metal ion transport	GO:0030001	289	0.027
cellular catabolic process	GO:0044248	295	0.027
nitrogen compound transport	GO:0071705	229	0.026
regulation of cellular component organization	GO:0051128	368	0.026
cellular component morphogenesis	GO:0032989	155	0.025
protein complex subunit organization	GO:0071822	302	0.025	Human
response to alkaloid	GO:0043279	132	0.025
response to nutrient	GO:0007584	248	0.025
regulation of cell development	GO:0060284	263	0.025
regulation of neurogenesis	GO:0050767	247	0.024
transcription from rna polymerase ii promoter	GO:0006366	252	0.023
protein complex assembly	GO:0006461	263	0.023	Human
blood circulation	GO:0008015	183	0.023
negative regulation of glutamate secretion	GO:0014050	9	0.022
tissue development	GO:0009888	252	0.022
neuron differentiation	GO:0030182	368	0.022
regulation of nucleic acid templated transcription	GO:1903506	380	0.022
regulation of cellular amino acid metabolic process	GO:0006521	2	0.022
cellular response to oxygen containing compound	GO:1901701	386	0.022
neuron projection development	GO:0031175	273	0.022
cellular ketone metabolic process	GO:0042180	51	0.021
programmed cell death	GO:0012501	392	0.021
regulation of phosphorus metabolic process	GO:0051174	349	0.021
response to peptide	GO:1901652	292	0.021
response to hexose	GO:0009746	144	0.021
peptidyl amino acid modification	GO:0018193	126	0.021
carbohydrate derivative metabolic process	GO:1901135	346	0.021
response to peptide hormone	GO:0043434	278	0.021
single organism behavior	GO:0044708	130	0.020
macromolecular complex assembly	GO:0065003	273	0.020	Human
signal release	GO:0023061	145	0.020
response to ketone	GO:1901654	182	0.020
negative regulation of cell death	GO:0060548	229	0.020
response to inorganic substance	GO:0010035	377	0.020
action potential	GO:0001508	54	0.020
regulation of cell differentiation	GO:0045595	320	0.020
regulation of membrane potential	GO:0042391	110	0.019
intracellular signal transduction	GO:0035556	314	0.019
catabolic process	GO:0009056	351	0.019
synaptic transmission	GO:0007268	235	0.019
nucleobase containing small molecule metabolic process	GO:0055086	316	0.019
regulation of blood circulation	GO:1903522	110	0.019
sensory perception	GO:0007600	101	0.018
multicellular organism reproduction	GO:0032504	233	0.018
positive regulation of cellular amine metabolic process	GO:0033240	3	0.018
positive regulation of blood circulation	GO:1903524	65	0.018
positive regulation of multicellular organismal process	GO:0051240	387	0.018
positive regulation of protein metabolic process	GO:0051247	178	0.017
secretion	GO:0046903	307	0.017
negative regulation of programmed cell death	GO:0043069	183	0.017
regulation of programmed cell death	GO:0043067	341	0.017
positive regulation of signal transduction	GO:0009967	175	0.017
response to acid chemical	GO:0001101	222	0.017
organic substance catabolic process	GO:1901575	316	0.017
regeneration	GO:0031099	163	0.017
macromolecule localization	GO:0033036	252	0.016
regulation of immune system process	GO:0002682	123	0.016
negative regulation of response to stimulus	GO:0048585	155	0.016
regulation of amino acid transport	GO:0051955	25	0.016
multicellular organismal reproductive process	GO:0048609	233	0.016
cell cell signaling	GO:0007267	335	0.016
regulation of anatomical structure size	GO:0090066	135	0.016
transmission of nerve impulse	GO:0019226	42	0.016
positive regulation of protein modification process	GO:0031401	142	0.016
response to organophosphorus	GO:0046683	102	0.016
glycosyl compound metabolic process	GO:1901657	182	0.016
response to mechanical stimulus	GO:0009612	134	0.016
positive regulation of developmental process	GO:0051094	283	0.016
cell migration	GO:0016477	197	0.016
regulation of cellular ketone metabolic process	GO:0010565	27	0.015
response to wounding	GO:0009611	254	0.015
eye morphogenesis	GO:0048592	4	0.015
regulation of cellular localization	GO:0060341	263	0.015
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.015
regulation of neuron differentiation	GO:0045664	208	0.015
cell morphogenesis involved in differentiation	GO:0000904	119	0.015
sulfur compound metabolic process	GO:0006790	70	0.014
calcium ion transport	GO:0006816	131	0.014
carboxylic acid metabolic process	GO:0019752	289	0.014
b cell differentiation	GO:0030183	2	0.014
neuron development	GO:0048666	286	0.014
small molecule biosynthetic process	GO:0044283	124	0.014
regulation of sodium ion transmembrane transporter activity	GO:2000649	4	0.014
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.014
regulation of blood vessel size	GO:0050880	89	0.014
cellular response to stress	GO:0033554	269	0.014
cytoplasmic transport	GO:0016482	115	0.014
negative regulation of apoptotic process	GO:0043066	181	0.014
negative regulation of cell communication	GO:0010648	158	0.014
negative regulation of signaling	GO:0023057	157	0.014
acute inflammatory response	GO:0002526	58	0.014
carbohydrate derivative biosynthetic process	GO:1901137	124	0.014
regulation of system process	GO:0044057	208	0.014
organ regeneration	GO:0031100	101	0.014
single organism carbohydrate metabolic process	GO:0044723	118	0.014
hormone transport	GO:0009914	121	0.013
defense response	GO:0006952	194	0.013
cellular cation homeostasis	GO:0030003	180	0.013
developmental process involved in reproduction	GO:0003006	159	0.013
response to purine containing compound	GO:0014074	126	0.013
cellular component assembly	GO:0022607	360	0.013	Human
regulation of rna metabolic process	GO:0051252	391	0.013
divalent inorganic cation homeostasis	GO:0072507	165	0.013
cellular component biogenesis	GO:0044085	368	0.013	Human
organophosphate metabolic process	GO:0019637	370	0.013
positive regulation of immune system process	GO:0002684	90	0.013
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.013
response to carbohydrate	GO:0009743	183	0.013
central nervous system development	GO:0007417	311	0.013
negative regulation of transport	GO:0051051	136	0.013
carbohydrate metabolic process	GO:0005975	130	0.013
oxoacid metabolic process	GO:0043436	290	0.013
positive regulation of biosynthetic process	GO:0009891	319	0.013
positive regulation of phosphate metabolic process	GO:0045937	262	0.013
regulation of ion transport	GO:0043269	245	0.013
ribose phosphate metabolic process	GO:0019693	235	0.013
cellular response to growth factor stimulus	GO:0071363	162	0.012
cellular component movement	GO:0006928	248	0.012
reproduction	GO:0000003	245	0.012
purine containing compound metabolic process	GO:0072521	253	0.012
calcium ion homeostasis	GO:0055074	162	0.012
regulation of cellular protein metabolic process	GO:0032268	267	0.012
reproductive system development	GO:0061458	128	0.012
regulation of hormone levels	GO:0010817	187	0.012
regulation of transmembrane transporter activity	GO:0022898	49	0.012
secretion by cell	GO:0032940	248	0.012
purine ribonucleotide metabolic process	GO:0009150	227	0.012
regulation of ion homeostasis	GO:2000021	63	0.012
retina morphogenesis in camera type eye	GO:0060042	1	0.012
l glutamate import	GO:0051938	2	0.012
positive regulation of cell proliferation	GO:0008284	249	0.012
response to monosaccharide	GO:0034284	159	0.012
response to glucose	GO:0009749	136	0.012
response to blue light	GO:0009637	1	0.012
regulation of signal transduction	GO:0009966	318	0.012
organelle organization	GO:0006996	266	0.012
regulation of jnk cascade	GO:0046328	19	0.012
regulation of protein phosphorylation	GO:0001932	183	0.012
positive regulation of molecular function	GO:0044093	230	0.011
angiotensin mediated drinking behavior	GO:0003051	2	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.011
axon development	GO:0061564	96	0.011
regulation of neuron projection development	GO:0010975	161	0.011
regulation of cell projection organization	GO:0031344	175	0.011
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.011
regulation of neurological system process	GO:0031644	43	0.011
positive regulation of phosphorus metabolic process	GO:0010562	262	0.011
organophosphate biosynthetic process	GO:0090407	143	0.011
rna metabolic process	GO:0016070	406	0.011
regulation of peptide hormone secretion	GO:0090276	80	0.011
cellular response to endogenous stimulus	GO:0071495	377	0.011
regulation of potassium ion transport	GO:0043266	29	0.011
cellular response to nitrogen compound	GO:1901699	210	0.011
regulation of tube size	GO:0035150	89	0.011
regulation of response to stress	GO:0080134	126	0.011
regulation of fat cell differentiation	GO:0045598	3	0.011
camp metabolic process	GO:0046058	63	0.011
organic cyclic compound catabolic process	GO:1901361	175	0.011
nucleoside phosphate metabolic process	GO:0006753	283	0.011
protein maturation	GO:0051604	68	0.011
positive regulation of phosphorylation	GO:0042327	177	0.011
maternal process involved in female pregnancy	GO:0060135	38	0.011
inorganic cation transmembrane transport	GO:0098662	202	0.011
response to mineralocorticoid	GO:0051385	49	0.011
positive regulation of ion transport	GO:0043270	94	0.011
cellular protein complex assembly	GO:0043623	44	0.011
vascular process in circulatory system	GO:0003018	96	0.011
positive regulation of protein phosphorylation	GO:0001934	135	0.011
locomotion	GO:0040011	237	0.010
sexual reproduction	GO:0019953	148	0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	2	0.010
lymphoid progenitor cell differentiation	GO:0002320	2	0.010
single organism catabolic process	GO:0044712	283	0.010
regulation of anion transport	GO:0044070	43	0.010
regulation of blood pressure	GO:0008217	83	0.010
cellular response to hormone stimulus	GO:0032870	247	0.010
innate immune response	GO:0045087	35	0.010
female pregnancy	GO:0007565	122	0.010
secretion by tissue	GO:0032941	37	0.010
response to other organism	GO:0051707	220	0.010
positive regulation of rna metabolic process	GO:0051254	203	0.010
development of primary sexual characteristics	GO:0045137	107	0.010
protein localization	GO:0008104	191	0.010
nucleoside phosphate catabolic process	GO:1901292	140	0.010
proteolysis	GO:0006508	175	0.010
mapk cascade	GO:0000165	140	0.010
positive regulation of cellular protein metabolic process	GO:0032270	167	0.010
muscle structure development	GO:0061061	87	0.010
g protein coupled receptor signaling pathway	GO:0007186	242	0.010

Scube1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.017
disease of anatomical entity	DOID:7	0.017
muscular disease	DOID:0080000	0.011
myopathy	DOID:423	0.011
muscle tissue disease	DOID:66	0.011

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