Rattus norvegicus

58 known processes

Htra1

HtrA serine peptidase 1

(Aliases: Prss11,MGC93339)

Htra1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carbohydrate derivative metabolic processGO:19011353460.111
organic substance catabolic processGO:19015753160.108
carboxylic acid metabolic processGO:00197522890.088
cellular response to endogenous stimulusGO:00714953770.086
Zebrafish Mouse
agingGO:00075682410.082
oxoacid metabolic processGO:00434362900.076
catabolic processGO:00090563510.072
positive regulation of multicellular organismal processGO:00512403870.070
apoptotic processGO:00069153810.070
Rat
cellular catabolic processGO:00442482950.067
positive regulation of response to stimulusGO:00485842850.065
cellular response to hormone stimulusGO:00328702470.060
multicellular organismal reproductive processGO:00486092330.059
intracellular signal transductionGO:00355563140.057
organonitrogen compound catabolic processGO:19015651790.052
regulation of multicellular organismal developmentGO:20000263760.049
positive regulation of cell proliferationGO:00082842490.049
negative regulation of cell deathGO:00605482290.048
Rat
positive regulation of intracellular signal transductionGO:19025331380.048
cellular amino acid metabolic processGO:00065201070.045
single organism reproductive processGO:00447022970.044
single organism biosynthetic processGO:00447113420.043
positive regulation of signal transductionGO:00099671750.043
lipid metabolic processGO:00066292830.043
Rat
regulation of body fluid levelsGO:0050878900.043
response to acid chemicalGO:00011012220.042
positive regulation of cell communicationGO:00106472710.042
response to glucocorticoidGO:00513842230.041
regulation of molecular functionGO:00650093980.041
negative regulation of programmed cell deathGO:00430691830.039
regulation of programmed cell deathGO:00430673410.039
Rat
multi organism reproductive processGO:00447032620.038
homeostatic processGO:00425923310.038
cellular ketone metabolic processGO:0042180510.037
reproductive processGO:00224143720.037
wound healingGO:00420601220.036
hormone metabolic processGO:0042445690.036
signal transduction by phosphorylationGO:00230141440.036
response to metal ionGO:00100382530.034
regulation of protein metabolic processGO:00512462890.032
response to nutrient levelsGO:00316673700.032
carbohydrate derivative catabolic processGO:19011361470.032
sexual reproductionGO:00199531480.031
response to inorganic substanceGO:00100353770.031
cellular amine metabolic processGO:0044106380.031
regulation of signal transductionGO:00099663180.031
Zebrafish Mouse
monocarboxylic acid metabolic processGO:00327871520.031
response to peptide hormoneGO:00434342780.030
regulation of catalytic activityGO:00507903040.030
chemical homeostasisGO:00488782920.029
regulation of neuron apoptotic processGO:0043523830.028
amine metabolic processGO:0009308380.028
regulation of protein localizationGO:0032880810.028
negative regulation of apoptotic processGO:00430661810.027
response to extracellular stimulusGO:00099913800.027
response to hexoseGO:00097461440.027
response to nutrientGO:00075842480.027
lipid biosynthetic processGO:00086101280.027
multicellular organism reproductionGO:00325042330.027
regulation of neuron deathGO:19012141150.027
cell type specific apoptotic processGO:00972851340.027
response to carbohydrateGO:00097431830.026
positive regulation of nervous system developmentGO:00519621780.026
peptidyl amino acid modificationGO:00181931260.026
regulation of hydrolase activityGO:00513361430.026
respiratory system developmentGO:0060541450.026
gamete generationGO:00072761240.026
positive regulation of protein metabolic processGO:00512471780.025
cellular response to oxygen containing compoundGO:19017013860.025
regulation of cell differentiationGO:00455953200.025
positive regulation of phosphate metabolic processGO:00459372620.025
neuron projection developmentGO:00311752730.024
regulation of cell developmentGO:00602842630.024
response to peptideGO:19016522920.024
organic acid metabolic processGO:00060822920.024
response to estrogenGO:00436272320.023
central nervous system developmentGO:00074173110.023
developmental growthGO:00485891000.023
reproductionGO:00000032450.023
brain developmentGO:00074202470.023
regulation of nervous system developmentGO:00519602640.023
programmed cell deathGO:00125013920.022
Rat
positive regulation of cellular amine metabolic processGO:003324030.022
protein phosphorylationGO:00064683450.022
positive regulation of signalingGO:00230562700.022
cellular response to organic cyclic compoundGO:00714072020.022
single organism catabolic processGO:00447122830.022
regulation of cellular amine metabolic processGO:003323880.021
positive regulation of phosphorylationGO:00423271770.021
regulation of apoptotic processGO:00429813350.021
Rat
growthGO:00400071650.021
cellular modified amino acid metabolic processGO:0006575610.020
organic cyclic compound catabolic processGO:19013611750.020
positive regulation of cellular protein metabolic processGO:00322701670.020
cellular lipid metabolic processGO:00442552080.019
Rat
positive regulation of catalytic activityGO:00430851840.019
response to insulinGO:00328681330.019
nucleobase containing small molecule metabolic processGO:00550863160.019
organophosphate metabolic processGO:00196373700.019
response to monosaccharideGO:00342841590.018
regulation of phosphorylationGO:00423252480.018
regulation of anatomical structure sizeGO:00900661350.018
proteolysisGO:00065081750.018
Mouse Rat
posttranscriptional regulation of gene expressionGO:0010608370.018
neuron developmentGO:00486662860.018
mapk cascadeGO:00001651400.017
response to oxidative stressGO:00069791860.017
nucleoside phosphate metabolic processGO:00067532830.017
single organism behaviorGO:00447081300.017
multicellular organismal homeostasisGO:0048871490.017
spermatogenesisGO:0007283990.017
protein maturationGO:0051604680.017
neuron deathGO:00709971270.017
regulation of cellular protein metabolic processGO:00322682670.017
positive regulation of cellular amino acid metabolic processGO:004576410.016
defense responseGO:00069521940.016
positive regulation of blood coagulationGO:003019440.016
positive regulation of hemostasisGO:190004840.016
response to decreased oxygen levelsGO:00362932370.016
neuron differentiationGO:00301823680.016
positive regulation of cell developmentGO:00107201760.016
regulation of hormone levelsGO:00108171870.015
behaviorGO:00076102050.015
male gamete generationGO:0048232990.015
positive regulation of cell differentiationGO:00455972170.015
response to biotic stimulusGO:00096072260.015
negative regulation of response to stimulusGO:00485851550.015
cellular response to lipidGO:00713962010.015
glycosyl compound metabolic processGO:19016571820.015
locomotionGO:00400112370.015
response to woundingGO:00096112540.015
transmembrane transportGO:00550854120.015
cellular homeostasisGO:00197252520.015
cellular response to external stimulusGO:00714961180.015
head developmentGO:00603222470.014
organic hydroxy compound metabolic processGO:19016151150.014
regulation of cellular component organizationGO:00511283680.014
negative regulation of neuron deathGO:1901215690.014
regulation of response to stressGO:00801341260.014
steroid biosynthetic processGO:0006694480.014
cellular response to metal ionGO:0071248550.014
regulation of cellular amino acid metabolic processGO:000652120.014
small gtpase mediated signal transductionGO:0007264360.014
sulfur compound metabolic processGO:0006790700.014
respiratory tube developmentGO:0030323430.013
positive regulation of phosphorus metabolic processGO:00105622620.013
positive regulation of cell deathGO:00109421840.013
Rat
regulation of membrane potentialGO:00423911100.013
glycosyl compound catabolic processGO:19016581260.013
secretionGO:00469033070.013
renal system developmentGO:0072001670.013
carboxylic acid catabolic processGO:0046395490.013
anion transportGO:00068201780.013
protein processingGO:0016485680.013
regulation of cellular ketone metabolic processGO:0010565270.013
vesicle mediated transportGO:00161921810.013
isoprenoid metabolic processGO:0006720450.013
Rat
sulfur compound biosynthetic processGO:0044272190.013
response to estradiolGO:00323551640.013
cellular component movementGO:00069282480.013
regulation of cell projection organizationGO:00313441750.012
multi multicellular organism processGO:00447061380.012
cognitionGO:0050890920.012
response to retinoic acidGO:0032526630.012
coagulationGO:0050817280.012
activation of cysteine type endopeptidase activityGO:009720240.012
organonitrogen compound biosynthetic processGO:19015661670.012
tissue homeostasisGO:0001894280.012
positive regulation of cell projection organizationGO:00313461110.012
neuronal action potentialGO:0019228350.012
carbohydrate derivative biosynthetic processGO:19011371240.012
positive regulation of nitrogen compound metabolic processGO:00511733340.012
regulation of phosphorus metabolic processGO:00511743490.012
positive regulation of molecular functionGO:00440932300.012
positive regulation of neuron projection developmentGO:0010976990.012
positive regulation of hydrolase activityGO:0051345860.012
positive regulation of developmental processGO:00510942830.012
heterocycle catabolic processGO:00467001670.012
regulation of cell proliferationGO:00421273590.011
cellular response to stressGO:00335542690.011
response to glucoseGO:00097491360.011
positive regulation of neuron differentiationGO:00456661260.011
adult locomotory behaviorGO:000834440.011
salivary gland developmentGO:000743130.011
regulation of lipid biosynthetic processGO:0046890380.011
cellular component assemblyGO:00226073600.011
regulation of growthGO:00400081050.011
regulation of defense responseGO:0031347680.011
cell adhesionGO:00071551100.011
cellular response to steroid hormone stimulusGO:0071383930.011
regulation of cell motilityGO:20001451310.011
response to radiationGO:00093141370.011
metal ion transportGO:00300012890.011
regulation of peptidase activityGO:0052547550.011
cell part morphogenesisGO:00329901230.011
response to ethanolGO:00454711620.011
positive regulation of epithelial cell migrationGO:0010634130.011
rho protein signal transductionGO:0007266110.010
monosaccharide metabolic processGO:0005996610.010
cellular chemical homeostasisGO:00550822470.010
female pregnancyGO:00075651220.010
carbohydrate metabolic processGO:00059751300.010
neurological system processGO:00508772190.010
negative regulation of metabolic processGO:00098923310.010
regulation of proteolysisGO:0030162660.010
glucose homeostasisGO:0042593750.010
regulation of phosphate metabolic processGO:00192203490.010

Htra1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.034
musculoskeletal system diseaseDOID:1700.034
disease of anatomical entityDOID:700.034
Human
bone development diseaseDOID:008000600.018
bone diseaseDOID:008000100.018
disease of metabolismDOID:001466700.012
nervous system diseaseDOID:86300.011
Human
inherited metabolic disorderDOID:65500.011
cardiovascular system diseaseDOID:128700.011