Rattus norvegicus

145 known processes

Ddit3

DNA-damage inducible transcript 3

(Aliases: CHOP,CHOP-10,Gadd153,MGC124604,Chop10)

Ddit3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of macromolecule metabolic processGO:00106052600.128
programmed cell deathGO:00125013920.121
negative regulation of cell deathGO:00605482290.111
nucleic acid templated transcriptionGO:00976593790.105
transcription dna templatedGO:00063513770.085
regulation of rna metabolic processGO:00512523910.084
regulation of cellular protein metabolic processGO:00322682670.083
rna biosynthetic processGO:00327743800.076
cellular response to stressGO:00335542690.075
regulation of protein metabolic processGO:00512462890.071
negative regulation of apoptotic processGO:00430661810.063
regulation of apoptotic processGO:00429813350.061
regulation of rna biosynthetic processGO:20011413810.060
regulation of cell differentiationGO:00455953200.060
Mouse
regulation of nucleic acid templated transcriptionGO:19035063800.059
regulation of phosphorus metabolic processGO:00511743490.059
negative regulation of metabolic processGO:00098923310.058
negative regulation of response to stimulusGO:00485851550.057
Mouse
regulation of molecular functionGO:00650093980.057
negative regulation of gene expressionGO:00106291990.057
catabolic processGO:00090563510.056
Human
protein refoldingGO:004202630.055
nucleobase containing small molecule metabolic processGO:00550863160.055
apoptotic processGO:00069153810.053
negative regulation of cellular metabolic processGO:00313242810.052
intracellular signal transductionGO:00355563140.052
Human Mouse
regulation of catalytic activityGO:00507903040.052
response to inorganic substanceGO:00100353770.048
regulation of cellular component organizationGO:00511283680.048
positive regulation of nitrogen compound metabolic processGO:00511733340.048
regulation of phosphate metabolic processGO:00192203490.047
response to external biotic stimulusGO:00432072210.046
cellular catabolic processGO:00442482950.046
Human
protein phosphorylationGO:00064683450.045
intracellular transportGO:00469071850.045
Mouse
positive regulation of cellular biosynthetic processGO:00313282950.044
regulation of cell proliferationGO:00421273590.044
nucleoside phosphate metabolic processGO:00067532830.043
organic acid metabolic processGO:00060822920.043
negative regulation of programmed cell deathGO:00430691830.042
response to extracellular stimulusGO:00099913800.041
transmembrane transportGO:00550854120.041
response to hypoxiaGO:00016662310.041
defense responseGO:00069521940.040
rna metabolic processGO:00160704060.040
organophosphate metabolic processGO:00196373700.040
carboxylic acid metabolic processGO:00197522890.040
response to decreased oxygen levelsGO:00362932370.039
carbohydrate derivative metabolic processGO:19011353460.038
negative regulation of transportGO:00510511360.038
positive regulation of nucleobase containing compound metabolic processGO:00459353190.038
g protein coupled receptor signaling pathwayGO:00071862420.037
transcription from rna polymerase ii promoterGO:00063662520.037
negative regulation of multicellular organismal processGO:00512412030.036
Human Mouse
homeostatic processGO:00425923310.036
Human Mouse
neuron deathGO:00709971270.036
Mouse
response to oxygen levelsGO:00704822650.036
cellular amino acid metabolic processGO:00065201070.035
cation transportGO:00068123820.035
Mouse
oxidation reduction processGO:00551143040.034
regulation of cellular localizationGO:00603412630.034
oxoacid metabolic processGO:00434362900.034
nucleotide metabolic processGO:00091172790.034
secretion by cellGO:00329402480.033
regulation of hydrolase activityGO:00513361430.033
positive regulation of multicellular organismal processGO:00512403870.033
Human
macromolecule localizationGO:00330362520.033
negative regulation of cellular protein metabolic processGO:00322691060.032
negative regulation of cell communicationGO:00106481580.032
Mouse
regulation of nervous system developmentGO:00519602640.031
positive regulation of response to stimulusGO:00485842850.031
neuron projection developmentGO:00311752730.031
neuron differentiationGO:00301823680.031
positive regulation of molecular functionGO:00440932300.031
positive regulation of macromolecule biosynthetic processGO:00105572470.031
negative regulation of nucleic acid templated transcriptionGO:19035071170.031
organic substance catabolic processGO:19015753160.030
Human
negative regulation of macromolecule biosynthetic processGO:00105581480.030
organelle organizationGO:00069962660.030
response to other organismGO:00517072200.030
purine ribonucleotide metabolic processGO:00091502270.030
regulation of purine nucleotide metabolic processGO:19005421150.030
ribonucleotide metabolic processGO:00092592310.029
metal ion homeostasisGO:00550651860.029
Mouse
single organism biosynthetic processGO:00447113420.029
central nervous system developmentGO:00074173110.028
cellular component movementGO:00069282480.028
regulation of nucleotide metabolic processGO:00061401170.028
circulatory system processGO:00030131830.028
regulation of cell developmentGO:00602842630.028
Mouse
neuron developmentGO:00486662860.028
negative regulation of cellular biosynthetic processGO:00313271610.028
negative regulation of nitrogen compound metabolic processGO:00511721610.027
single organism catabolic processGO:00447122830.027
secretionGO:00469033070.027
regulation of ion transportGO:00432692450.027
negative regulation of developmental processGO:00510931250.027
Human Mouse
regulation of transcription dna templatedGO:00063553740.027
protein localizationGO:00081041910.026
response to nutrient levelsGO:00316673700.026
negative regulation of transcription dna templatedGO:00458921160.026
cellular amine metabolic processGO:0044106380.026
brain developmentGO:00074202470.025
regulation of transcription from rna polymerase ii promoterGO:00063572340.025
cellular component biogenesisGO:00440853680.025
cellular response to topologically incorrect proteinGO:003596730.025
Mouse
regulation of cellular amino acid metabolic processGO:000652120.025
regulation of phosphorylationGO:00423252480.024
response to biotic stimulusGO:00096072260.024
positive regulation of phosphorus metabolic processGO:00105622620.024
purine nucleoside triphosphate metabolic processGO:00091441410.024
amine metabolic processGO:0009308380.024
cell projection organizationGO:00300303020.024
purine containing compound metabolic processGO:00725212530.024
monovalent inorganic cation transportGO:00156721720.024
regulation of neuron differentiationGO:00456642080.024
purine ribonucleotide catabolic processGO:00091541360.024
cellular protein localizationGO:00346131220.023
regulation of protein modification processGO:00313991940.023
positive regulation of biosynthetic processGO:00098913190.023
negative regulation of rna metabolic processGO:00512531230.023
positive regulation of apoptotic processGO:00430651540.023
regulation of signal transductionGO:00099663180.023
Mouse
cellular homeostasisGO:00197252520.023
Human Mouse
single organism intracellular transportGO:19025821660.023
Mouse
negative regulation of molecular functionGO:00440921330.023
ribose phosphate metabolic processGO:00196932350.022
purine nucleotide metabolic processGO:00061632290.022
nucleoside metabolic processGO:00091161790.022
anatomical structure morphogenesisGO:00096532980.022
glycosyl compound metabolic processGO:19016571820.022
cellular cation homeostasisGO:00300031800.022
Mouse
regulation of response to stressGO:00801341260.021
negative regulation of biosynthetic processGO:00098901680.021
regulation of neurogenesisGO:00507672470.021
regulation of secretionGO:00510462240.021
negative regulation of phosphorus metabolic processGO:0010563800.021
nitrogen compound transportGO:00717052290.021
regulation of multicellular organismal developmentGO:20000263760.021
Human Mouse
positive regulation of transcription dna templatedGO:00458931970.021
ion homeostasisGO:00508012120.021
Mouse
organonitrogen compound biosynthetic processGO:19015661670.021
response to estrogenGO:00436272320.021
head developmentGO:00603222470.021
regulation of system processGO:00440572080.021
regulation of neuron deathGO:19012141150.020
Mouse
negative regulation of protein metabolic processGO:00512481140.020
macromolecular complex subunit organizationGO:00439333390.020
organonitrogen compound catabolic processGO:19015651790.020
regulation of cellular amine metabolic processGO:003323880.020
behaviorGO:00076102050.020
positive regulation of cell differentiationGO:00455972170.020
response to woundingGO:00096112540.020
proteolysisGO:00065081750.020
Human
negative regulation of rna biosynthetic processGO:19026791180.020
regulation of cellular ketone metabolic processGO:0010565270.020
axis specificationGO:000979840.019
Mouse
multicellular organism reproductionGO:00325042330.019
positive regulation of transportGO:00510502450.019
cell type specific apoptotic processGO:00972851340.019
Mouse
tissue developmentGO:00098882520.019
Mouse
cytoplasmic transportGO:00164821150.019
Mouse
cellular response to endogenous stimulusGO:00714953770.019
positive regulation of protein metabolic processGO:00512471780.019
cellular response to oxygen containing compoundGO:19017013860.019
regulation of programmed cell deathGO:00430673410.019
multi organism reproductive processGO:00447032620.019
heterocycle catabolic processGO:00467001670.019
positive regulation of nervous system developmentGO:00519621780.019
cellular response to growth factor stimulusGO:00713631620.019
chemical homeostasisGO:00488782920.018
Mouse
positive regulation of phosphate metabolic processGO:00459372620.018
response to growth factorGO:00708481890.018
response to molecule of bacterial originGO:00022371940.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
organophosphate catabolic processGO:00464341480.018
divalent inorganic cation homeostasisGO:00725071650.018
Mouse
cellular response to organic cyclic compoundGO:00714072020.018
regulation of cell projection organizationGO:00313441750.018
regenerationGO:00310991630.018
single organism cellular localizationGO:19025801020.018
regulation of immune system processGO:00026821230.018
response to lipopolysaccharideGO:00324961910.018
regulation of membrane potentialGO:00423911100.018
regulation of metal ion transportGO:00109591180.018
reproductive processGO:00224143720.017
positive regulation of protein modification processGO:00314011420.017
cell cell signalingGO:00072673350.017
establishment of protein localizationGO:00451841410.017
multicellular organismal reproductive processGO:00486092330.017
response to peptideGO:19016522920.017
response to hydrogen peroxideGO:0042542890.017
inorganic cation transmembrane transportGO:00986622020.017
heart morphogenesisGO:000300730.017
small gtpase mediated signal transductionGO:0007264360.017
neurological system processGO:00508772190.017
reactive oxygen species metabolic processGO:0072593370.017
regulation of neuron projection developmentGO:00109751610.017
mapk cascadeGO:00001651400.017
cellular ketone metabolic processGO:0042180510.017
agingGO:00075682410.017
regulation of secretion by cellGO:19035302080.017
signal transduction by phosphorylationGO:00230141440.017
positive regulation of neurogenesisGO:00507691650.017
nucleoside phosphate catabolic processGO:19012921400.017
positive regulation of cellular component organizationGO:00511302000.016
regulation of cellular catabolic processGO:00313291010.016
purine nucleoside metabolic processGO:00422781690.016
response to metal ionGO:00100382530.016
cellular metal ion homeostasisGO:00068751720.016
Mouse
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
amide transportGO:00428861050.016
purine ribonucleoside metabolic processGO:00461281680.016
response to cytokineGO:00340972150.016
cell morphogenesis involved in neuron differentiationGO:00486671060.016
positive regulation of neuron differentiationGO:00456661260.016
response to acid chemicalGO:00011012220.016
ribonucleoside triphosphate metabolic processGO:00091991410.016
cellular response to oxidative stressGO:0034599760.016
ras protein signal transductionGO:0007265290.016
cellular nitrogen compound catabolic processGO:00442701630.016
nucleobase containing compound catabolic processGO:00346551520.016
regulation of protein phosphorylationGO:00019321830.016
response to bacteriumGO:00096172000.016
response to estradiolGO:00323551640.016
positive regulation of rna metabolic processGO:00512542030.016
positive regulation of cell developmentGO:00107201760.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
localization of cellGO:00516742020.016
reproductionGO:00000032450.015
locomotionGO:00400112370.015
negative regulation of catalytic activityGO:00430861030.015
cation transmembrane transportGO:00986552630.015
positive regulation of cellular amine metabolic processGO:003324030.015
negative regulation of cell differentiationGO:0045596990.015
Mouse
dna metabolic processGO:0006259960.015
cellular component morphogenesisGO:00329891550.015
positive regulation of cell deathGO:00109421840.015
negative regulation of phosphate metabolic processGO:0045936800.015
ribonucleoside metabolic processGO:00091191740.015
positive regulation of rna biosynthetic processGO:19026801970.015
cell morphogenesisGO:00009021420.015
regulation of catabolic processGO:00098941130.015
organic anion transportGO:00157111320.015
positive regulation of developmental processGO:00510942830.015
protein transportGO:00150311320.015
purine nucleotide biosynthetic processGO:0006164830.015
cellular macromolecule localizationGO:00707271220.015
maintenance of locationGO:0051235170.015
Mouse
cellular component assemblyGO:00226073600.015
regulation of intracellular signal transductionGO:19025312180.015
cell projection morphogenesisGO:00488581230.015
carbohydrate derivative catabolic processGO:19011361470.015
purine ribonucleoside catabolic processGO:00461301240.015
organic cyclic compound catabolic processGO:19013611750.015
cation homeostasisGO:00550801950.015
Mouse
potassium ion transportGO:0006813970.015
negative regulation of neuron deathGO:1901215690.015
regulation of transferase activityGO:00513381230.015
cell migrationGO:00164771970.014
blood circulationGO:00080151830.014
response to ketoneGO:19016541820.014
purine nucleoside triphosphate catabolic processGO:00091461220.014
nucleotide catabolic processGO:00091661390.014
immune responseGO:00069551040.014
regulation of mapk cascadeGO:00434081160.014
ion transmembrane transportGO:00342203650.014
single organism organelle organizationGO:19025891800.014
axon developmentGO:0061564960.014
negative regulation of cellular component organizationGO:0051129830.014
ribonucleoside catabolic processGO:00424541260.014
organic acid transportGO:00158491160.014
carboxylic acid transportGO:00469421150.013
cellular lipid metabolic processGO:00442552080.013
generation of precursor metabolites and energyGO:0006091620.013
negative regulation of ion transportGO:0043271510.013
positive regulation of phosphorylationGO:00423271770.013
gastrulationGO:000736920.013
regulation of homeostatic processGO:00328441010.013
Mouse
protein complex subunit organizationGO:00718223020.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
positive regulation of cellular protein metabolic processGO:00322701670.013
synaptic growth at neuromuscular junctionGO:005112410.013
regulation of kinase activityGO:00435491170.013
organophosphate biosynthetic processGO:00904071430.013
single organism reproductive processGO:00447022970.013
purine containing compound catabolic processGO:00725231380.013
purine nucleoside catabolic processGO:00061521240.013
negative regulation of signal transductionGO:0009968830.013
Mouse
regulation of anatomical structure sizeGO:00900661350.013
cell part morphogenesisGO:00329901230.013
cellular calcium ion homeostasisGO:00068741600.012
Mouse
immune system processGO:00023762040.012
ribonucleotide catabolic processGO:00092611360.012
response to reactive oxygen speciesGO:00003021200.012
response to radiationGO:00093141370.012
aromatic compound catabolic processGO:00194391680.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
cell morphogenesis involved in differentiationGO:00009041190.012
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.012
anion transportGO:00068201780.012
regulation of hormone levelsGO:00108171870.012
renal system developmentGO:0072001670.012
positive regulation of protein phosphorylationGO:00019341350.012
spermatogenesisGO:0007283990.012
positive regulation of immune system processGO:0002684900.012
cell cycleGO:00070491010.012
metal ion transportGO:00300012890.012
Mouse
membrane organizationGO:0061024940.012
regulation of cell growthGO:0001558850.012
positive regulation of programmed cell deathGO:00430681570.012
calcium ion transportGO:00068161310.012
Mouse
purine nucleotide catabolic processGO:00061951360.012
regulation of protein processingGO:0070613500.012
response to nutrientGO:00075842480.012
cellular response to cytokine stimulusGO:00713451270.012
negative regulation of signalingGO:00230571570.011
Mouse
multicellular organism growthGO:003526410.011
positive regulation of hydrolase activityGO:0051345860.011
peptide transportGO:0015833970.011
nucleoside phosphate biosynthetic processGO:19012931020.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.011
nucleoside catabolic processGO:00091641260.011
cellular response to lipidGO:00713962010.011
regulation of proteasomal protein catabolic processGO:006113640.011
microtubule organizing center organizationGO:003102310.011
positive regulation of cell proliferationGO:00082842490.011
regulation of protein maturationGO:1903317500.011
glycosyl compound catabolic processGO:19016581260.011
response to toxic substanceGO:00096361330.011
regulation of protein kinase activityGO:00458591050.011
kidney developmentGO:0001822670.011
purine containing compound biosynthetic processGO:0072522850.011
cellular response to biotic stimulusGO:0071216590.011
positive regulation of nucleotide metabolic processGO:0045981910.011
positive regulation of gene expressionGO:00106282440.011
vesicle mediated transportGO:00161921810.011
inorganic ion transmembrane transportGO:00986602290.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
positive regulation of signalingGO:00230562700.011
energy derivation by oxidation of organic compoundsGO:0015980460.011
cold acclimationGO:000963110.011
positive regulation of response to external stimulusGO:0032103510.011
cellular response to nitrogen compoundGO:19016992100.011
growthGO:00400071650.011
positive regulation of catabolic processGO:0009896780.011
defense response to gram negative bacteriumGO:005082930.010
nucleotide biosynthetic processGO:0009165980.010
positive regulation of purine nucleotide catabolic processGO:0033123530.010
protein complex assemblyGO:00064612630.010
myosin filament assemblyGO:003103410.010
regulation of anatomical structure morphogenesisGO:00226031410.010
purine nucleoside monophosphate metabolic processGO:0009126840.010
response to carbohydrateGO:00097431830.010
amino acid transportGO:0006865700.010
cellular divalent inorganic cation homeostasisGO:00725031620.010
Mouse
regulation of cellular response to stressGO:0080135490.010
synaptic transmissionGO:00072682350.010
protein localization to membraneGO:0072657360.010
embryonic pattern specificationGO:000988010.010
cellular response to organonitrogen compoundGO:00714171970.010
nucleoside triphosphate metabolic processGO:00091411440.010
regulation of blood circulationGO:19035221100.010
response to ethanolGO:00454711620.010
regulation of defense responseGO:0031347680.010
cell motilityGO:00488702020.010
purine ribonucleoside monophosphate metabolic processGO:0009167840.010
cellular response to external stimulusGO:00714961180.010
positive regulation of cellular catabolic processGO:0031331710.010

Ddit3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.017
disease of anatomical entityDOID:700.017
disease of metabolismDOID:001466700.010
musculoskeletal system diseaseDOID:1700.010