| binding of sperm to zona pellucida | GO:0007339 | 1 | 0.862 | Mouse |
| cell cell recognition | GO:0009988 | 1 | 0.592 | Mouse |
| sperm egg recognition | GO:0035036 | 1 | 0.454 | Mouse |
| single fertilization | GO:0007338 | 3 | 0.404 | Mouse |
| protein folding | GO:0006457 | 12 | 0.397 | Yeast |
| mitotic spindle organization | GO:0007052 | 2 | 0.371 | Fly |
| cell recognition | GO:0008037 | 11 | 0.352 | Mouse |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.276 | |
| cellular component assembly | GO:0022607 | 360 | 0.245 | Fly |
| multi organism reproductive process | GO:0044703 | 262 | 0.240 | Mouse |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.189 | |
| toxin transport | GO:1901998 | 3 | 0.187 | Mouse |
| sexual reproduction | GO:0019953 | 148 | 0.180 | Mouse |
| protein complex assembly | GO:0006461 | 263 | 0.155 | Fly |
| cellular component biogenesis | GO:0044085 | 368 | 0.152 | Fly |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.149 | Fly |
| regulation of apoptotic process | GO:0042981 | 335 | 0.143 | |
| fertilization | GO:0009566 | 3 | 0.125 | Mouse |
| protein complex biogenesis | GO:0070271 | 263 | 0.120 | Fly |
| protein complex subunit organization | GO:0071822 | 302 | 0.117 | Fly |
| single organism reproductive process | GO:0044702 | 297 | 0.115 | Mouse |
| macromolecular complex assembly | GO:0065003 | 273 | 0.113 | Fly |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.096 | |
| cytoskeleton organization | GO:0007010 | 111 | 0.085 | Fly |
| programmed cell death | GO:0012501 | 392 | 0.082 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.076 | |
| regulation of molecular function | GO:0065009 | 398 | 0.072 | |
| microtubule based process | GO:0007017 | 36 | 0.070 | Fly |
| copper ion transport | GO:0006825 | 6 | 0.069 | |
| spindle organization | GO:0007051 | 2 | 0.067 | Fly |
| organelle organization | GO:0006996 | 266 | 0.067 | Fly |
| single organism organelle organization | GO:1902589 | 180 | 0.066 | Fly |
| cellular catabolic process | GO:0044248 | 295 | 0.066 | |
| catabolic process | GO:0009056 | 351 | 0.065 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.064 | |
| apoptotic process | GO:0006915 | 381 | 0.060 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.059 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.059 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.051 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.051 | |
| protein targeting to membrane | GO:0006612 | 11 | 0.050 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.049 | |
| mitotic cell cycle process | GO:1903047 | 35 | 0.048 | Fly |
| macromolecule catabolic process | GO:0009057 | 58 | 0.045 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.045 | |
| reproductive process | GO:0022414 | 372 | 0.044 | Mouse |
| rna metabolic process | GO:0016070 | 406 | 0.043 | |
| reproduction | GO:0000003 | 245 | 0.043 | Mouse |
| regulation of programmed cell death | GO:0043067 | 341 | 0.042 | |
| mitotic cell cycle | GO:0000278 | 49 | 0.042 | Fly |
| centrosome organization | GO:0051297 | 1 | 0.039 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 141 | 0.039 | |
| regulation of retinal cell programmed cell death | GO:0046668 | 1 | 0.037 | |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.034 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.034 | |
| proteolysis | GO:0006508 | 175 | 0.033 | |
| sensory organ development | GO:0007423 | 74 | 0.033 | |
| response to oxygen levels | GO:0070482 | 265 | 0.033 | |
| regulation of neuron death | GO:1901214 | 115 | 0.032 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.032 | |
| microtubule organizing center organization | GO:0031023 | 1 | 0.031 | |
| regulation of cell development | GO:0060284 | 263 | 0.031 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.030 | |
| transcription dna templated | GO:0006351 | 377 | 0.030 | |
| protein transport | GO:0015031 | 132 | 0.028 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.028 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.028 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.028 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.027 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.027 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.026 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 19 | 0.026 | |
| regulation of response to stress | GO:0080134 | 126 | 0.026 | |
| regulation of protein localization | GO:0032880 | 81 | 0.026 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.026 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.025 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.025 | |
| cell cycle process | GO:0022402 | 57 | 0.025 | Fly |
| gamete generation | GO:0007276 | 124 | 0.025 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.024 | |
| organelle assembly | GO:0070925 | 22 | 0.024 | Fly |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 3 | 0.024 | |
| ncrna processing | GO:0034470 | 3 | 0.024 | |
| cation transmembrane transport | GO:0098655 | 263 | 0.023 | |
| neurological system process | GO:0050877 | 219 | 0.023 | |
| regulation of insulin secretion involved in cellular response to glucose stimulus | GO:0061178 | 14 | 0.023 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.023 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.023 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.023 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.023 | |
| centrosome cycle | GO:0007098 | 1 | 0.022 | |
| immune system process | GO:0002376 | 204 | 0.022 | |
| amine metabolic process | GO:0009308 | 38 | 0.022 | |
| homeostatic process | GO:0042592 | 331 | 0.022 | |
| organelle fission | GO:0048285 | 25 | 0.022 | Fly |
| organophosphate metabolic process | GO:0019637 | 370 | 0.021 | |
| cellular response to peptide | GO:1901653 | 133 | 0.021 | |
| microtubule cytoskeleton organization | GO:0000226 | 25 | 0.021 | Fly |
| cell type specific apoptotic process | GO:0097285 | 134 | 0.020 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.020 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.020 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.020 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.019 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.019 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.019 | |
| locomotion | GO:0040011 | 237 | 0.019 | |
| positive regulation of cell death | GO:0010942 | 184 | 0.018 | |
| cellular macromolecular complex assembly | GO:0034622 | 58 | 0.018 | |
| blood vessel morphogenesis | GO:0048514 | 58 | 0.018 | |
| nucleotide metabolic process | GO:0009117 | 279 | 0.017 | |
| cardiac muscle cell apoptotic process | GO:0010659 | 13 | 0.017 | |
| aging | GO:0007568 | 241 | 0.017 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.017 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.017 | |
| response to radiation | GO:0009314 | 137 | 0.017 | |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.017 | |
| regulation of immune system process | GO:0002682 | 123 | 0.017 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.017 | |
| regulation of transferase activity | GO:0051338 | 123 | 0.017 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.016 | |
| positive regulation of protein modification process | GO:0031401 | 142 | 0.016 | |
| negative regulation of gene expression | GO:0010629 | 199 | 0.016 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.016 | |
| regulation of membrane potential | GO:0042391 | 110 | 0.016 | |
| blood circulation | GO:0008015 | 183 | 0.016 | |
| cellular macromolecule catabolic process | GO:0044265 | 29 | 0.016 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.016 | |
| positive regulation of apoptotic process | GO:0043065 | 154 | 0.016 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.016 | |
| protein homooligomerization | GO:0051260 | 91 | 0.015 | |
| spermatid nucleus differentiation | GO:0007289 | 1 | 0.015 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.015 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.015 | |
| triglyceride homeostasis | GO:0070328 | 2 | 0.015 | |
| macromolecule localization | GO:0033036 | 252 | 0.015 | |
| negative regulation of neuron death | GO:1901215 | 69 | 0.015 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.015 | |
| cell cycle | GO:0007049 | 101 | 0.015 | Fly |
| protein tetramerization | GO:0051262 | 38 | 0.014 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.014 | |
| male gamete generation | GO:0048232 | 99 | 0.014 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.014 | |
| negative regulation of biosynthetic process | GO:0009890 | 168 | 0.014 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 106 | 0.014 | |
| cellular homeostasis | GO:0019725 | 252 | 0.014 | |
| organ morphogenesis | GO:0009887 | 75 | 0.014 | |
| negative regulation of autophagy | GO:0010507 | 1 | 0.014 | |
| defense response | GO:0006952 | 194 | 0.013 | |
| negative regulation of response to stimulus | GO:0048585 | 155 | 0.013 | |
| rna catabolic process | GO:0006401 | 3 | 0.013 | |
| cellular response to stress | GO:0033554 | 269 | 0.013 | |
| regulation of transcription initiation from rna polymerase ii promoter | GO:0060260 | 3 | 0.013 | |
| neuron death | GO:0070997 | 127 | 0.013 | |
| cytoplasmic microtubule organization | GO:0031122 | 4 | 0.013 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 118 | 0.013 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.013 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.013 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.013 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.012 | |
| de novo protein folding | GO:0006458 | 2 | 0.012 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.012 | |
| response to uv c | GO:0010225 | 2 | 0.012 | |
| negative regulation of glycoprotein metabolic process | GO:1903019 | 2 | 0.012 | |
| negative regulation of molecular function | GO:0044092 | 133 | 0.012 | |
| immune effector process | GO:0002252 | 53 | 0.012 | |
| regulation of response to external stimulus | GO:0032101 | 106 | 0.012 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.012 | |
| cardiac muscle adaptation | GO:0014887 | 1 | 0.012 | |
| negative regulation of catalytic activity | GO:0043086 | 103 | 0.012 | |
| cellular response to alcohol | GO:0097306 | 87 | 0.012 | |
| osteoblast differentiation | GO:0001649 | 26 | 0.012 | |
| negative regulation of cell proliferation | GO:0008285 | 119 | 0.011 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.011 | |
| positive regulation of transcription initiation from rna polymerase ii promoter | GO:0060261 | 3 | 0.011 | |
| response to inorganic substance | GO:0010035 | 377 | 0.011 | |
| acylglycerol homeostasis | GO:0055090 | 2 | 0.011 | |
| positive regulation of protein phosphorylation | GO:0001934 | 135 | 0.011 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.011 | |
| regulation of neutrophil apoptotic process | GO:0033029 | 4 | 0.011 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 117 | 0.011 | |
| magnesium ion homeostasis | GO:0010960 | 2 | 0.011 | |
| regulation of embryonic development | GO:0045995 | 2 | 0.011 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.011 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.011 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.011 | |
| negative regulation of glucose transport | GO:0010829 | 4 | 0.011 | |
| cardiovascular system development | GO:0072358 | 134 | 0.011 | |
| response to hypoxia | GO:0001666 | 231 | 0.011 | |
| positive regulation of rna metabolic process | GO:0051254 | 203 | 0.010 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.010 | |
| histone ubiquitination | GO:0016574 | 1 | 0.010 | |
| organic cyclic compound catabolic process | GO:1901361 | 175 | 0.010 | |
| positive regulation of peptidyl threonine phosphorylation | GO:0010800 | 1 | 0.010 | |
| protein autoubiquitination | GO:0051865 | 2 | 0.010 | |
| response to histamine | GO:0034776 | 3 | 0.010 | |
| positive regulation of transcription dna templated | GO:0045893 | 197 | 0.010 | |
| dorsal ventral pattern formation | GO:0009953 | 4 | 0.010 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.010 | |