IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Gdf6

growth differentiation factor 6

(Aliases: gdf16)

Ensembl: ENSRNOG00000007810
RGD: 620104
Entrez: 252834
UniProtKB: Q6HA10

Process Predictions
Disease Predictions

Gdf6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
cation transport	GO:0006812	382	0.125
inorganic cation transmembrane transport	GO:0098662	202	0.095
metal ion transport	GO:0030001	289	0.090
cation transmembrane transport	GO:0098655	263	0.086
regulation of apoptotic process	GO:0042981	335	0.073	Rat
carboxylic acid metabolic process	GO:0019752	289	0.069
organic acid metabolic process	GO:0006082	292	0.064
cellular amino acid metabolic process	GO:0006520	107	0.061
ion transmembrane transport	GO:0034220	365	0.058
potassium ion transport	GO:0006813	97	0.045
oxoacid metabolic process	GO:0043436	290	0.042
negative regulation of apoptotic process	GO:0043066	181	0.041	Rat
regulation of cellular amine metabolic process	GO:0033238	8	0.041
neuron differentiation	GO:0030182	368	0.039	Mouse
transmembrane transport	GO:0055085	412	0.039
reproductive process	GO:0022414	372	0.039	Rat
regulation of cellular amino acid metabolic process	GO:0006521	2	0.039
amine metabolic process	GO:0009308	38	0.037
regulation of rna metabolic process	GO:0051252	391	0.037	Human Mouse Rat
transcription dna templated	GO:0006351	377	0.036	Human Mouse Rat
rna biosynthetic process	GO:0032774	380	0.036	Human Mouse Rat
cellular calcium ion homeostasis	GO:0006874	160	0.036
defense response	GO:0006952	194	0.035
nucleic acid templated transcription	GO:0097659	379	0.033	Human Mouse Rat
regulation of neuron differentiation	GO:0045664	208	0.033	Mouse
inorganic ion transmembrane transport	GO:0098660	229	0.032
regulation of nucleic acid templated transcription	GO:1903506	380	0.032	Human Mouse Rat
cellular amine metabolic process	GO:0044106	38	0.029
regulation of rna biosynthetic process	GO:2001141	381	0.028	Human Mouse Rat
secretion	GO:0046903	307	0.027
secretion by cell	GO:0032940	248	0.027
negative regulation of cell death	GO:0060548	229	0.027	Rat
neuron projection development	GO:0031175	273	0.026
cellular ion homeostasis	GO:0006873	184	0.026
apoptotic process	GO:0006915	381	0.025	Rat
protein oligomerization	GO:0051259	191	0.025
regulation of programmed cell death	GO:0043067	341	0.024	Rat
response to nutrient levels	GO:0031667	370	0.024	Rat
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.024
regulation of multicellular organismal development	GO:2000026	376	0.024	Mouse
programmed cell death	GO:0012501	392	0.024	Rat
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.024
protein complex assembly	GO:0006461	263	0.023
positive regulation of cellular amine metabolic process	GO:0033240	3	0.022
regulation of transcription dna templated	GO:0006355	374	0.022	Human Mouse Rat
response to metal ion	GO:0010038	253	0.022
rna metabolic process	GO:0016070	406	0.022	Human Mouse Rat
cellular component biogenesis	GO:0044085	368	0.021	Rat
cellular chemical homeostasis	GO:0055082	247	0.021
central nervous system development	GO:0007417	311	0.021	Rat
single organism organelle organization	GO:1902589	180	0.021	Rat
response to ketone	GO:1901654	182	0.020
multicellular organism reproduction	GO:0032504	233	0.020	Rat
ion homeostasis	GO:0050801	212	0.020
protein complex biogenesis	GO:0070271	263	0.020
intracellular transport	GO:0046907	185	0.020	Rat
regulation of neuron projection development	GO:0010975	161	0.020
neuron development	GO:0048666	286	0.020
negative regulation of signaling	GO:0023057	157	0.020	Rat
cellular response to oxygen containing compound	GO:1901701	386	0.020	Rat
chemical homeostasis	GO:0048878	292	0.019
negative regulation of programmed cell death	GO:0043069	183	0.019	Rat
monovalent inorganic cation transport	GO:0015672	172	0.019
divalent inorganic cation homeostasis	GO:0072507	165	0.019
neuronal action potential	GO:0019228	35	0.019
regulation of molecular function	GO:0065009	398	0.019	Rat
regulation of protein phosphorylation	GO:0001932	183	0.019	Human
protein complex subunit organization	GO:0071822	302	0.018
macromolecular complex assembly	GO:0065003	273	0.018
intracellular signal transduction	GO:0035556	314	0.018	Rat
response to acid chemical	GO:0001101	222	0.018
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.018	Human Rat
response to carbohydrate	GO:0009743	183	0.018
regulation of secretion by cell	GO:1903530	208	0.018
response to corticosteroid	GO:0031960	235	0.018
axon development	GO:0061564	96	0.018
sodium ion transport	GO:0006814	82	0.018
catabolic process	GO:0009056	351	0.018
regulation of cell projection organization	GO:0031344	175	0.018
response to estrogen	GO:0043627	232	0.017	Rat
regulation of protein metabolic process	GO:0051246	289	0.017	Human
multi organism reproductive process	GO:0044703	262	0.017
regulation of nervous system development	GO:0051960	264	0.017	Mouse
homeostatic process	GO:0042592	331	0.017
cytosolic calcium ion homeostasis	GO:0051480	140	0.017
positive regulation of protein modification process	GO:0031401	142	0.016	Human
cellular cation homeostasis	GO:0030003	180	0.016
cellular ketone metabolic process	GO:0042180	51	0.016
negative regulation of cell communication	GO:0010648	158	0.016	Rat
organelle organization	GO:0006996	266	0.016	Rat
negative regulation of macromolecule metabolic process	GO:0010605	260	0.016
reactive oxygen species metabolic process	GO:0072593	37	0.016	Rat
brain development	GO:0007420	247	0.016	Rat
regulation of response to stress	GO:0080134	126	0.016	Rat
cellular metal ion homeostasis	GO:0006875	172	0.016
calcium ion homeostasis	GO:0055074	162	0.016
macromolecular complex subunit organization	GO:0043933	339	0.016
sensory perception	GO:0007600	101	0.015
neurological system process	GO:0050877	219	0.015
circulatory system process	GO:0003013	183	0.015
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.015
regulation of cellular ketone metabolic process	GO:0010565	27	0.015
g protein coupled receptor signaling pathway	GO:0007186	242	0.015
positive regulation of neuron projection development	GO:0010976	99	0.015
positive regulation of molecular function	GO:0044093	230	0.015
growth	GO:0040007	165	0.015
positive regulation of rna metabolic process	GO:0051254	203	0.015	Human Rat
metal ion homeostasis	GO:0055065	186	0.015
muscle system process	GO:0003012	115	0.015	Rat
protein homooligomerization	GO:0051260	91	0.014
positive regulation of gene expression	GO:0010628	244	0.014	Human Rat
regulation of cell differentiation	GO:0045595	320	0.014	Mouse Rat
regulation of secretion	GO:0051046	224	0.014
carbohydrate derivative metabolic process	GO:1901135	346	0.014
regulation of cellular protein metabolic process	GO:0032268	267	0.014	Human
reactive nitrogen species metabolic process	GO:2001057	1	0.014
negative regulation of protein metabolic process	GO:0051248	114	0.014
negative regulation of multicellular organismal process	GO:0051241	203	0.014
response to glucocorticoid	GO:0051384	223	0.014
response to dexamethasone	GO:0071548	49	0.014
positive regulation of signal transduction	GO:0009967	175	0.014	Human
behavior	GO:0007610	205	0.014
transmission of nerve impulse	GO:0019226	42	0.014
organophosphate metabolic process	GO:0019637	370	0.014
single organism reproductive process	GO:0044702	297	0.013	Rat
regulation of cell development	GO:0060284	263	0.013	Mouse
response to peptide	GO:1901652	292	0.013	Rat
regulation of g0 to g1 transition	GO:0070316	3	0.013
locomotion	GO:0040011	237	0.013
nucleobase containing small molecule metabolic process	GO:0055086	316	0.013
response to hypoxia	GO:0001666	231	0.013	Rat
chromosome segregation	GO:0007059	2	0.013
regulation of system process	GO:0044057	208	0.013	Rat
heart morphogenesis	GO:0003007	3	0.013
positive regulation of cell motility	GO:2000147	97	0.013
adult locomotory behavior	GO:0008344	4	0.013
response to inorganic substance	GO:0010035	377	0.013	Rat
organ formation	GO:0048645	3	0.013
regulation of cell proliferation	GO:0042127	359	0.013
positive regulation of protein phosphorylation	GO:0001934	135	0.013	Human
positive regulation of protein metabolic process	GO:0051247	178	0.013	Human
cellular nitrogen compound catabolic process	GO:0044270	163	0.013
positive regulation of cellular protein metabolic process	GO:0032270	167	0.013	Human
positive regulation of neuron differentiation	GO:0045666	126	0.013	Mouse
regulation of cellular localization	GO:0060341	263	0.012	Rat
lipid metabolic process	GO:0006629	283	0.012
negative regulation of metabolic process	GO:0009892	331	0.012
organic anion transport	GO:0015711	132	0.012
regulation of cellular component organization	GO:0051128	368	0.012
reactive oxygen species biosynthetic process	GO:1903409	8	0.012
regulation of body fluid levels	GO:0050878	90	0.012
response to oxidative stress	GO:0006979	186	0.012	Rat
protein heterooligomerization	GO:0051291	89	0.012
negative regulation of cellular protein metabolic process	GO:0032269	106	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.012	Human Rat
regulation of catalytic activity	GO:0050790	304	0.012
response to alkaloid	GO:0043279	132	0.012
axis specification	GO:0009798	4	0.012
rho protein signal transduction	GO:0007266	11	0.012
multicellular organismal reproductive process	GO:0048609	233	0.012	Rat
positive regulation of catalytic activity	GO:0043085	184	0.012
asymmetric protein localization	GO:0008105	2	0.012
cation homeostasis	GO:0055080	195	0.011
potassium ion transmembrane transport	GO:0071805	71	0.011
positive regulation of signaling	GO:0023056	270	0.011	Human
positive regulation of cell proliferation	GO:0008284	249	0.011
regeneration	GO:0031099	163	0.011
multicellular organismal signaling	GO:0035637	44	0.011
response to vitamin	GO:0033273	131	0.011	Rat
second messenger mediated signaling	GO:0019932	51	0.011
signal transduction by phosphorylation	GO:0023014	144	0.011
regulation of membrane potential	GO:0042391	110	0.011
regulation of neurogenesis	GO:0050767	247	0.011	Mouse
purine containing compound metabolic process	GO:0072521	253	0.011
regulation of reactive oxygen species metabolic process	GO:2000377	26	0.011	Rat
developmental growth	GO:0048589	100	0.011
monocarboxylic acid metabolic process	GO:0032787	152	0.011
macromolecule localization	GO:0033036	252	0.011	Rat
cellular protein localization	GO:0034613	122	0.011	Rat
muscle contraction	GO:0006936	88	0.011
oxidation reduction process	GO:0055114	304	0.011
striated muscle contraction	GO:0006941	44	0.011
response to monosaccharide	GO:0034284	159	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.011
positive regulation of ion transport	GO:0043270	94	0.011
cellular component assembly	GO:0022607	360	0.011	Rat
cellular component morphogenesis	GO:0032989	155	0.010	Rat
regulation of phosphate metabolic process	GO:0019220	349	0.010	Human Rat
regulation of signal transduction	GO:0009966	318	0.010	Human Rat
nucleoside metabolic process	GO:0009116	179	0.010
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.010
sequestering of calcium ion	GO:0051208	8	0.010
cellular response to organic cyclic compound	GO:0071407	202	0.010
nucleoside phosphate metabolic process	GO:0006753	283	0.010

Gdf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.015	Human
	nervous system disease	DOID:863	0	0.015	Human

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network