Rattus norvegicus

0 known processes

Rtkn2

rhotekin 2

(Aliases: Plekhk1)

Rtkn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.046
carboxylic acid metabolic processGO:00197522890.042
oxoacid metabolic processGO:00434362900.041
protein phosphorylationGO:00064683450.039
regulation of phosphorus metabolic processGO:00511743490.038
rna metabolic processGO:00160704060.038
cellular ketone metabolic processGO:0042180510.037
anatomical structure morphogenesisGO:00096532980.037
cellular amino acid metabolic processGO:00065201070.037
response to inorganic substanceGO:00100353770.036
positive regulation of nitrogen compound metabolic processGO:00511733340.036
intracellular signal transductionGO:00355563140.036
regulation of multicellular organismal developmentGO:20000263760.035
regulation of transcription dna templatedGO:00063553740.034
programmed cell deathGO:00125013920.034
cellular component biogenesisGO:00440853680.034
cellular component assemblyGO:00226073600.033
protein complex assemblyGO:00064612630.033
macromolecular complex subunit organizationGO:00439333390.032
regulation of cellular amino acid metabolic processGO:000652120.032
apoptotic processGO:00069153810.031
cellular response to endogenous stimulusGO:00714953770.031
regulation of nucleic acid templated transcriptionGO:19035063800.031
amine metabolic processGO:0009308380.031
regulation of rna biosynthetic processGO:20011413810.030
regulation of cellular ketone metabolic processGO:0010565270.030
cation transportGO:00068123820.030
central nervous system developmentGO:00074173110.030
nucleic acid templated transcriptionGO:00976593790.029
regulation of molecular functionGO:00650093980.029
regulation of cellular amine metabolic processGO:003323880.029
protein complex subunit organizationGO:00718223020.029
regulation of apoptotic processGO:00429813350.029
reproductive processGO:00224143720.029
positive regulation of multicellular organismal processGO:00512403870.029
cellular amine metabolic processGO:0044106380.028
negative regulation of metabolic processGO:00098923310.028
positive regulation of biosynthetic processGO:00098913190.028
regulation of rna metabolic processGO:00512523910.027
rna biosynthetic processGO:00327743800.027
regulation of cellular component organizationGO:00511283680.027
response to extracellular stimulusGO:00099913800.027
transcription dna templatedGO:00063513770.027
cellular response to oxygen containing compoundGO:19017013860.027
organelle organizationGO:00069962660.027
regulation of nervous system developmentGO:00519602640.027
macromolecular complex assemblyGO:00650032730.027
regulation of programmed cell deathGO:00430673410.027
regulation of protein metabolic processGO:00512462890.027
catabolic processGO:00090563510.026
cell projection organizationGO:00300303020.026
positive regulation of nucleobase containing compound metabolic processGO:00459353190.026
neuron differentiationGO:00301823680.026
regulation of phosphate metabolic processGO:00192203490.025
carbohydrate derivative metabolic processGO:19011353460.025
regulation of phosphorylationGO:00423252480.025
regulation of protein modification processGO:00313991940.025
positive regulation of cellular biosynthetic processGO:00313282950.025
neuron projection developmentGO:00311752730.025
regulation of cell differentiationGO:00455953200.025
response to nutrient levelsGO:00316673700.025
neurological system processGO:00508772190.024
regulation of neurogenesisGO:00507672470.024
regulation of cell proliferationGO:00421273590.024
single organism biosynthetic processGO:00447113420.024
positive regulation of macromolecule biosynthetic processGO:00105572470.024
positive regulation of developmental processGO:00510942830.024
positive regulation of gene expressionGO:00106282440.023
cellular response to stressGO:00335542690.023
protein complex biogenesisGO:00702712630.023
single organism reproductive processGO:00447022970.023
organophosphate metabolic processGO:00196373700.023
reproductionGO:00000032450.022
regulation of cellular protein metabolic processGO:00322682670.022
regulation of catalytic activityGO:00507903040.022
single organism catabolic processGO:00447122830.022
multi organism reproductive processGO:00447032620.022
positive regulation of phosphorus metabolic processGO:00105622620.022
positive regulation of cell communicationGO:00106472710.022
response to metal ionGO:00100382530.022
positive regulation of cellular amino acid metabolic processGO:004576410.022
regulation of signal transductionGO:00099663180.022
ion transmembrane transportGO:00342203650.022
transcription from rna polymerase ii promoterGO:00063662520.022
positive regulation of rna metabolic processGO:00512542030.022
intracellular transportGO:00469071850.022
cellular response to nitrogen compoundGO:19016992100.022
protein localizationGO:00081041910.021
chemical homeostasisGO:00488782920.021
secretionGO:00469033070.021
regulation of cell developmentGO:00602842630.021
positive regulation of cellular amine metabolic processGO:003324030.021
multicellular organism reproductionGO:00325042330.021
single organism intracellular transportGO:19025821660.021
protein oligomerizationGO:00512591910.021
metal ion transportGO:00300012890.020
multicellular organismal reproductive processGO:00486092330.020
negative regulation of cell deathGO:00605482290.020
organic substance catabolic processGO:19015753160.020
positive regulation of transportGO:00510502450.020
response to oxidative stressGO:00069791860.020
regulation of protein phosphorylationGO:00019321830.020
regulation of system processGO:00440572080.020
response to nutrientGO:00075842480.020
negative regulation of macromolecule metabolic processGO:00106052600.020
positive regulation of protein metabolic processGO:00512471780.020
positive regulation of signalingGO:00230562700.020
negative regulation of cellular metabolic processGO:00313242810.020
locomotionGO:00400112370.020
nucleobase containing small molecule metabolic processGO:00550863160.020
positive regulation of molecular functionGO:00440932300.020
positive regulation of nucleic acid templated transcriptionGO:19035081970.020
regulation of neuron differentiationGO:00456642080.020
negative regulation of apoptotic processGO:00430661810.019
negative regulation of multicellular organismal processGO:00512412030.019
positive regulation of response to stimulusGO:00485842850.019
nucleotide metabolic processGO:00091172790.019
neuron developmentGO:00486662860.019
macromolecule localizationGO:00330362520.019
regulation of cellular localizationGO:00603412630.019
positive regulation of phosphate metabolic processGO:00459372620.019
regulation of membrane potentialGO:00423911100.019
secretion by cellGO:00329402480.019
positive regulation of rna biosynthetic processGO:19026801970.019
head developmentGO:00603222470.019
brain developmentGO:00074202470.019
lipid metabolic processGO:00066292830.019
homeostatic processGO:00425923310.019
cellular catabolic processGO:00442482950.019
nucleoside phosphate metabolic processGO:00067532830.019
agingGO:00075682410.019
response to acid chemicalGO:00011012220.019
regulation of transcription from rna polymerase ii promoterGO:00063572340.019
small gtpase mediated signal transductionGO:0007264360.019
purine containing compound metabolic processGO:00725212530.018
positive regulation of cellular protein metabolic processGO:00322701670.018
transmembrane transportGO:00550854120.018
negative regulation of cell communicationGO:00106481580.018
regulation of cell projection organizationGO:00313441750.018
positive regulation of phosphorylationGO:00423271770.018
response to peptideGO:19016522920.018
response to carbohydrateGO:00097431830.018
positive regulation of protein modification processGO:00314011420.018
positive regulation of transcription dna templatedGO:00458931970.018
regulation of intracellular signal transductionGO:19025312180.018
cellular response to hormone stimulusGO:00328702470.018
negative regulation of programmed cell deathGO:00430691830.018
positive regulation of cell proliferationGO:00082842490.018
response to woundingGO:00096112540.018
positive regulation of cellular component organizationGO:00511302000.018
regulation of neuron projection developmentGO:00109751610.017
response to hypoxiaGO:00016662310.017
response to oxygen levelsGO:00704822650.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
nitrogen compound transportGO:00717052290.017
negative regulation of natural killer cell mediated immunityGO:000271640.017
cell cell signalingGO:00072673350.017
peptidyl amino acid modificationGO:00181931260.017
single organism organelle organizationGO:19025891800.017
positive regulation of cell developmentGO:00107201760.017
response to growth factorGO:00708481890.017
anterior posterior pattern specificationGO:000995210.017
ras protein signal transductionGO:0007265290.017
heart morphogenesisGO:000300730.017
cellular chemical homeostasisGO:00550822470.017
calcium ion homeostasisGO:00550741620.016
muscle system processGO:00030121150.016
tissue developmentGO:00098882520.016
purine ribonucleotide metabolic processGO:00091502270.016
cellular response to organonitrogen compoundGO:00714171970.016
positive regulation of cell differentiationGO:00455972170.016
regulation of response to stressGO:00801341260.016
response to peptide hormoneGO:00434342780.016
cellular component movementGO:00069282480.016
cardiovascular system developmentGO:00723581340.016
positive regulation of nervous system developmentGO:00519621780.016
blood circulationGO:00080151830.016
purine nucleotide metabolic processGO:00061632290.016
ribose phosphate metabolic processGO:00196932350.016
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.016
immune system processGO:00023762040.016
defense responseGO:00069521940.016
circulatory system processGO:00030131830.016
negative regulation of signalingGO:00230571570.016
action potentialGO:0001508540.016
negative regulation of developmental processGO:00510931250.016
cellular response to growth factor stimulusGO:00713631620.016
cellular homeostasisGO:00197252520.015
response to external biotic stimulusGO:00432072210.015
organic cyclic compound catabolic processGO:19013611750.015
response to glucocorticoidGO:00513842230.015
establishment of protein localizationGO:00451841410.015
positive regulation of cell deathGO:00109421840.015
cation homeostasisGO:00550801950.015
negative regulation of innate immune responseGO:004582440.015
cellular lipid metabolic processGO:00442552080.015
cellular calcium ion homeostasisGO:00068741600.015
negative regulation of response to stimulusGO:00485851550.015
cellular response to lipidGO:00713962010.015
ion homeostasisGO:00508012120.015
heterocycle catabolic processGO:00467001670.015
ribonucleotide metabolic processGO:00092592310.015
regulation of transferase activityGO:00513381230.015
response to decreased oxygen levelsGO:00362932370.015
axis specificationGO:000979840.014
metal ion homeostasisGO:00550651860.014
cellular component morphogenesisGO:00329891550.014
cellular response to organic cyclic compoundGO:00714072020.014
regulation of secretionGO:00510462240.014
g protein coupled receptor signaling pathwayGO:00071862420.014
positive regulation of signal transductionGO:00099671750.014
rhythmic processGO:00485111560.014
purine nucleoside metabolic processGO:00422781690.014
positive regulation of protein phosphorylationGO:00019341350.014
cellular protein localizationGO:00346131220.014
protein transportGO:00150311320.014
ribonucleoside metabolic processGO:00091191740.014
negative regulation of molecular functionGO:00440921330.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
response to estrogenGO:00436272320.014
carbohydrate metabolic processGO:00059751300.014
circulatory system developmentGO:00723591340.014
positive regulation of neurogenesisGO:00507691650.014
response to cytokineGO:00340972150.014
signal transduction by phosphorylationGO:00230141440.014
regulation of ion transportGO:00432692450.014
response to monosaccharideGO:00342841590.014
single organism cellular localizationGO:19025801020.014
monovalent inorganic cation transportGO:00156721720.014
glycosyl compound metabolic processGO:19016571820.014
cell type specific apoptotic processGO:00972851340.014
cellular nitrogen compound catabolic processGO:00442701630.014
nucleoside metabolic processGO:00091161790.014
response to hexoseGO:00097461440.013
positive regulation of catalytic activityGO:00430851840.013
response to reactive oxygen speciesGO:00003021200.013
proteolysisGO:00065081750.013
response to ketoneGO:19016541820.013
organonitrogen compound catabolic processGO:19015651790.013
regulation of secretion by cellGO:19035302080.013
immune responseGO:00069551040.013
negative regulation of biosynthetic processGO:00098901680.013
chromosome segregationGO:000705920.013
regulation of immune system processGO:00026821230.013
cell migrationGO:00164771970.013
localization of cellGO:00516742020.013
organonitrogen compound biosynthetic processGO:19015661670.013
inorganic ion transmembrane transportGO:00986602290.013
regulation of anatomical structure sizeGO:00900661350.013
behaviorGO:00076102050.013
response to ethanolGO:00454711620.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
gamete generationGO:00072761240.013
cellular metal ion homeostasisGO:00068751720.013
gastrulationGO:000736920.013
regulation of kinase activityGO:00435491170.013
sexual reproductionGO:00199531480.013
negative regulation of gene expressionGO:00106291990.013
cellular cation homeostasisGO:00300031800.013
reactive oxygen species metabolic processGO:0072593370.013
synaptic transmissionGO:00072682350.013
negative regulation of transportGO:00510511360.013
vesicle mediated transportGO:00161921810.013
response to toxic substanceGO:00096361330.013
aromatic compound catabolic processGO:00194391680.013
nucleobase containing compound catabolic processGO:00346551520.013
eye morphogenesisGO:004859240.013
positive regulation of apoptotic processGO:00430651540.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
synaptic growth at neuromuscular junctionGO:005112410.013
growthGO:00400071650.013
cytoplasmic transportGO:00164821150.013
regulation of anatomical structure morphogenesisGO:00226031410.013
mapk cascadeGO:00001651400.013
oxidation reduction processGO:00551143040.013
carbohydrate derivative biosynthetic processGO:19011371240.013
gland developmentGO:00487321550.013
regulation of metal ion transportGO:00109591180.012
single organism carbohydrate metabolic processGO:00447231180.012
cellular ion homeostasisGO:00068731840.012
signal releaseGO:00230611450.012
regulation of protein kinase activityGO:00458591050.012
response to glucoseGO:00097491360.012
negative regulation of nervous system developmentGO:0051961790.012
purine ribonucleoside metabolic processGO:00461281680.012
positive regulation of neuron differentiationGO:00456661260.012
response to alkaloidGO:00432791320.012
response to molecule of bacterial originGO:00022371940.012
developmental growthGO:00485891000.012
divalent inorganic cation transportGO:00725111340.012
cell motilityGO:00488702020.012
embryonic pattern specificationGO:000988010.012
response to amino acidGO:0043200750.012
antigen receptor mediated signaling pathwayGO:005085110.012
cell projection morphogenesisGO:00488581230.012
dna metabolic processGO:0006259960.012
developmental process involved in reproductionGO:00030061590.012
cellular macromolecule localizationGO:00707271220.012
inflammatory responseGO:00069541500.012
ribonucleoside catabolic processGO:00424541260.012
response to vitaminGO:00332731310.012
response to transition metal nanoparticleGO:19902671220.012
regenerationGO:00310991630.012
cation transmembrane transportGO:00986552630.012
regulation of blood circulationGO:19035221100.012
positive regulation of intracellular signal transductionGO:19025331380.012
reactive nitrogen species metabolic processGO:200105710.012
negative regulation of protein metabolic processGO:00512481140.012
actin filament based processGO:0030029860.012
salivary gland developmentGO:000743130.011
cytokine biosynthetic processGO:004208930.011
response to purine containing compoundGO:00140741260.011
response to biotic stimulusGO:00096072260.011
regulation of organelle organizationGO:0033043800.011
calcium ion transportGO:00068161310.011
cytosolic calcium ion homeostasisGO:00514801400.011
divalent inorganic cation homeostasisGO:00725071650.011
regulation of catabolic processGO:00098941130.011
spermatogenesisGO:0007283990.011
protein heterooligomerizationGO:0051291890.011
negative regulation of cellular biosynthetic processGO:00313271610.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
response to estradiolGO:00323551640.011
nucleoside phosphate catabolic processGO:19012921400.011
female pregnancyGO:00075651220.011
nucleoside triphosphate catabolic processGO:00091431230.011
cell morphogenesisGO:00009021420.011
regulation of hormone levelsGO:00108171870.011
cell part morphogenesisGO:00329901230.011
negative regulation of cellular component organizationGO:0051129830.011
regulation of mapk cascadeGO:00434081160.011
carbohydrate derivative catabolic processGO:19011361470.011
sex differentiationGO:00075481130.011
neuronal action potentialGO:0019228350.011
multicellular organismal signalingGO:0035637440.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
divalent metal ion transportGO:00708381320.011
organophosphate biosynthetic processGO:00904071430.011
negative regulation of cell differentiationGO:0045596990.011
hormone secretionGO:00468791150.011
male gamete generationGO:0048232990.011
regulation of nucleotide metabolic processGO:00061401170.011
spindle organizationGO:000705120.011
regulation of neuron apoptotic processGO:0043523830.011
regulation of cellular component biogenesisGO:0044087860.011
neuron projection morphogenesisGO:00488121220.011
membrane organizationGO:0061024940.011
organophosphate catabolic processGO:00464341480.011
negative regulation of cell cycle phase transitionGO:190198840.010
multi multicellular organism processGO:00447061380.010
leukocyte activationGO:0045321760.010
reactive oxygen species biosynthetic processGO:190340980.010
purine nucleotide catabolic processGO:00061951360.010
vascular process in circulatory systemGO:0003018960.010
lipid storageGO:001991510.010
reproductive system developmentGO:00614581280.010
cell activationGO:0001775970.010
cell morphogenesis involved in differentiationGO:00009041190.010
positive regulation of cell projection organizationGO:00313461110.010
nucleotide catabolic processGO:00091661390.010
ncrna processingGO:003447030.010
nucleoside triphosphate metabolic processGO:00091411440.010
negative regulation of neurogenesisGO:0050768780.010
regulation of canonical wnt signaling pathwayGO:006082840.010
rna localizationGO:000640340.010
sequestering of metal ionGO:005123890.010
rho protein signal transductionGO:0007266110.010
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.010
regulation of neuron deathGO:19012141150.010
positive regulation of neuron projection developmentGO:0010976990.010
negative regulation of cellular protein metabolic processGO:00322691060.010

Rtkn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
disease of metabolismDOID:001466700.015
central nervous system diseaseDOID:33100.011
musculoskeletal system diseaseDOID:1700.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011
cancerDOID:16200.011
sensory system diseaseDOID:005015500.010