Rattus norvegicus

63 known processes

Pck1

phosphoenolpyruvate carboxykinase 1 (soluble)

(Aliases: Pepck,PEPCK-C,GTP,PCK,MGC93820,RATPEPCK)

Pck1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.483
cellular catabolic processGO:00442482950.305
organic acid metabolic processGO:00060822920.272
catabolic processGO:00090563510.236
alpha amino acid metabolic processGO:1901605710.220
carboxylic acid metabolic processGO:00197522890.209
response to corticosteroidGO:00319602350.208
Rat
aromatic amino acid family catabolic processGO:000907470.183
single organism catabolic processGO:00447122830.155
response to acid chemicalGO:00011012220.143
response to peptideGO:19016522920.138
Human
response to monosaccharideGO:00342841590.138
Rat
positive regulation of transportGO:00510502450.134
Rat
response to carbohydrateGO:00097431830.131
Rat
chemical homeostasisGO:00488782920.128
oxidation reduction processGO:00551143040.124
Rat
response to inorganic substanceGO:00100353770.124
regulation of response to external stimulusGO:00321011060.124
acylglycerol metabolic processGO:0006639210.104
nitrogen compound transportGO:00717052290.098
Rat
aromatic compound catabolic processGO:00194391680.090
cellular response to hormone stimulusGO:00328702470.088
monocarboxylic acid metabolic processGO:00327871520.087
cellular amino acid metabolic processGO:00065201070.084
regulation of response to stressGO:00801341260.084
cellular metal ion homeostasisGO:00068751720.075
cellular response to organic cyclic compoundGO:00714072020.069
nucleobase containing small molecule metabolic processGO:00550863160.069
Rat
small molecule catabolic processGO:0044282590.067
macromolecular complex assemblyGO:00650032730.066
cellular chemical homeostasisGO:00550822470.066
Rat
organic substance catabolic processGO:19015753160.066
response to peptide hormoneGO:00434342780.065
Human
homeostatic processGO:00425923310.065
cation transportGO:00068123820.065
glycerolipid metabolic processGO:0046486670.061
response to glucocorticoidGO:00513842230.060
Rat
defense responseGO:00069521940.059
organic acid catabolic processGO:0016054490.057
protein homooligomerizationGO:0051260910.055
long chain fatty acid metabolic processGO:0001676320.055
cellular response to oxygen containing compoundGO:19017013860.054
Rat
liver developmentGO:0001889900.054
transmembrane transportGO:00550854120.053
g protein coupled receptor signaling pathwayGO:00071862420.053
wnt signaling pathway calcium modulating pathwayGO:000722310.053
organ regenerationGO:00311001010.053
blood circulationGO:00080151830.053
organic cyclic compound catabolic processGO:19013611750.051
carbohydrate derivative catabolic processGO:19011361470.051
cellular response to peptideGO:19016531330.050
cellular modified amino acid metabolic processGO:0006575610.050
response to hexoseGO:00097461440.050
Rat
organonitrogen compound catabolic processGO:19015651790.050
multi organism reproductive processGO:00447032620.050
fatty acid metabolic processGO:0006631990.049
cellular component biogenesisGO:00440853680.049
carbohydrate derivative metabolic processGO:19011353460.049
reproductive processGO:00224143720.049
response to glucoseGO:00097491360.047
Rat
response to antibioticGO:0046677390.046
alpha amino acid catabolic processGO:1901606200.046
alkaloid metabolic processGO:000982030.045
nucleoside phosphate metabolic processGO:00067532830.044
Rat
response to growth factorGO:00708481890.044
head developmentGO:00603222470.044
epoxygenase p450 pathwayGO:001937310.044
heterocycle catabolic processGO:00467001670.044
circulatory system processGO:00030131830.043
response to metal ionGO:00100382530.043
regulation of cellular ketone metabolic processGO:0010565270.041
protein complex assemblyGO:00064612630.041
cell adhesionGO:00071551100.041
lipid transportGO:0006869610.041
cellular response to peptide hormone stimulusGO:00713751200.040
cellular ketone metabolic processGO:0042180510.039
cellular response to insulin stimulusGO:0032869810.039
cellular nitrogen compound catabolic processGO:00442701630.038
regulation of cell growthGO:0001558850.038
cellular response to abiotic stimulusGO:0071214850.038
multi multicellular organism processGO:00447061380.037
isoprenoid metabolic processGO:0006720450.037
organophosphate metabolic processGO:00196373700.036
Rat
regulation of peptide secretionGO:0002791820.035
Rat
hepaticobiliary system developmentGO:0061008900.035
regulation of cellular component organizationGO:00511283680.035
ion transmembrane transportGO:00342203650.035
response to sulfur dioxideGO:001047730.034
cellular response to nitrogen compoundGO:19016992100.034
vitamin d receptor signaling pathwayGO:007056110.034
exogenous drug catabolic processGO:004273810.033
response to estrogenGO:00436272320.033
cellular ion homeostasisGO:00068731840.033
gland developmentGO:00487321550.033
response to nutrientGO:00075842480.033
protein complex subunit organizationGO:00718223020.032
response to organophosphorusGO:00466831020.032
central nervous system developmentGO:00074173110.032
cellular response to hexose stimulusGO:0071331650.032
Rat
organic acid biosynthetic processGO:0016053830.032
cellular component assemblyGO:00226073600.031
glucose homeostasisGO:0042593750.031
carbohydrate homeostasisGO:0033500750.030
dicarboxylic acid metabolic processGO:0043648420.030
brain developmentGO:00074202470.030
aromatic amino acid family metabolic processGO:000907290.030
placenta developmentGO:0001890220.030
protein complex biogenesisGO:00702712630.030
cell growthGO:00160491040.029
agingGO:00075682410.029
hormone secretionGO:00468791150.029
Rat
response to biotic stimulusGO:00096072260.029
cellular homeostasisGO:00197252520.028
Rat
positive regulation of signalingGO:00230562700.028
Rat
regulation of catabolic processGO:00098941130.028
cellular response to endogenous stimulusGO:00714953770.028
protein oligomerizationGO:00512591910.027
response to reactive oxygen speciesGO:00003021200.027
regulation of protein metabolic processGO:00512462890.027
neutral lipid metabolic processGO:0006638210.027
purine nucleoside metabolic processGO:00422781690.026
regulation of cellular catabolic processGO:00313291010.026
regulation of immunoglobulin productionGO:000263740.026
reproductive system developmentGO:00614581280.025
response to hypoxiaGO:00016662310.025
amine metabolic processGO:0009308380.025
response to xenobiotic stimulusGO:0009410230.025
terpenoid metabolic processGO:0006721370.025
response to ionizing radiationGO:0010212590.025
response to extracellular stimulusGO:00099913800.025
cellular lipid metabolic processGO:00442552080.025
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.025
regenerationGO:00310991630.025
secretionGO:00469033070.024
Rat
regulation of response to woundingGO:1903034690.024
trichloroethylene metabolic processGO:001897910.024
regulation of defense responseGO:0031347680.024
response to vitaminGO:00332731310.024
peptide hormone secretionGO:0030072840.024
Rat
folic acid containing compound metabolic processGO:0006760100.023
choline transportGO:001587140.023
purine nucleoside triphosphate catabolic processGO:00091461220.023
ion homeostasisGO:00508012120.023
multicellular organism reproductionGO:00325042330.023
response to woundingGO:00096112540.023
regulation of wound healingGO:0061041140.023
cellular amine metabolic processGO:0044106380.022
response to toxic substanceGO:00096361330.022
multicellular organismal reproductive processGO:00486092330.022
regulation of body fluid levelsGO:0050878900.022
glycosyl compound metabolic processGO:19016571820.022
cellular cation homeostasisGO:00300031800.022
lipid metabolic processGO:00066292830.022
regulation of cellular amine metabolic processGO:003323880.022
response to ketoneGO:19016541820.022
regulation of cellular amino acid metabolic processGO:000652120.021
response to bacteriumGO:00096172000.021
peptide transportGO:0015833970.021
Rat
peptide secretionGO:0002790860.020
Rat
steroid biosynthetic processGO:0006694480.020
ribonucleoside metabolic processGO:00091191740.020
negative regulation of transportGO:00510511360.020
nucleoside triphosphate metabolic processGO:00091411440.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
purine ribonucleoside metabolic processGO:00461281680.020
small molecule biosynthetic processGO:00442831240.020
glycogen metabolic processGO:0005977230.020
response to estradiolGO:00323551640.020
neural crest cell migrationGO:000175510.020
glutamine family amino acid metabolic processGO:0009064150.020
response to dexamethasoneGO:0071548490.020
regulation of cellular response to stressGO:0080135490.019
response to nutrient levelsGO:00316673700.019
immune system processGO:00023762040.019
ras protein signal transductionGO:0007265290.019
organonitrogen compound biosynthetic processGO:19015661670.019
biological adhesionGO:00226101100.019
single organism biosynthetic processGO:00447113420.019
macromolecular complex subunit organizationGO:00439333390.019
positive regulation of catabolic processGO:0009896780.019
maternal process involved in female pregnancyGO:0060135380.019
reproductionGO:00000032450.019
divalent inorganic cation homeostasisGO:00725071650.018
hormone transportGO:00099141210.018
Rat
purine containing compound metabolic processGO:00725212530.018
negative regulation of programmed cell deathGO:00430691830.018
regulation of synaptic transmissionGO:00508041410.018
protein phosphorylationGO:00064683450.018
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.018
nucleoside catabolic processGO:00091641260.018
cellular amino acid catabolic processGO:0009063210.018
organophosphate catabolic processGO:00464341480.018
telencephalon developmentGO:0021537620.018
response to oxygen levelsGO:00704822650.018
insecticide metabolic processGO:001714340.018
organic hydroxy compound transportGO:0015850770.018
positive regulation of blood coagulationGO:003019440.018
nucleobase containing compound catabolic processGO:00346551520.017
hemostasisGO:0007599260.017
negative regulation of multicellular organismal processGO:00512412030.017
purine ribonucleotide catabolic processGO:00091541360.017
regulation of protein phosphorylationGO:00019321830.017
heart morphogenesisGO:000300730.017
protein localizationGO:00081041910.017
arachidonic acid metabolic processGO:0019369200.017
purine ribonucleoside triphosphate metabolic processGO:00092051400.017
cellular response to organonitrogen compoundGO:00714171970.017
divalent inorganic cation transportGO:00725111340.016
cofactor metabolic processGO:0051186950.016
Rat
regulation of coagulationGO:0050818110.016
cellular response to carbohydrate stimulusGO:0071322720.016
Rat
ribose phosphate metabolic processGO:00196932350.016
nucleoside metabolic processGO:00091161790.016
spermatogenesisGO:0007283990.016
positive regulation of cellular component organizationGO:00511302000.016
cellular response to monosaccharide stimulusGO:0071326670.016
Rat
nucleoside phosphate catabolic processGO:19012921400.016
neuron differentiationGO:00301823680.016
locomotionGO:00400112370.016
coagulationGO:0050817280.016
regulation of cellular component movementGO:00512701500.016
regulation of locomotionGO:00400121480.016
nucleotide catabolic processGO:00091661390.016
female pregnancyGO:00075651220.015
regulation of extracellular matrix constituent secretionGO:000333020.015
positive regulation of cellular amine metabolic processGO:003324030.015
apoptotic processGO:00069153810.015
response to oxidative stressGO:00069791860.015
carboxylic acid catabolic processGO:0046395490.015
positive regulation of immunoglobulin productionGO:000263940.015
hepatocyte proliferationGO:007257430.015
positive regulation of response to stimulusGO:00485842850.015
positive regulation of insulin secretionGO:0032024360.015
Rat
negative regulation of neuron differentiationGO:0045665620.014
response to fatty acidGO:0070542650.014
purine nucleotide catabolic processGO:00061951360.014
lipid storageGO:001991510.014
regulation of multicellular organismal developmentGO:20000263760.014
response to osmotic stressGO:0006970420.014
cellular response to stressGO:00335542690.014
membrane organizationGO:0061024940.014
regulation of hormone levelsGO:00108171870.014
Rat
positive regulation of peptide secretionGO:0002793520.014
Rat
positive regulation of multicellular organismal processGO:00512403870.014
extracellular matrix constituent secretionGO:007027840.014
response to transition metal nanoparticleGO:19902671220.014
negative regulation of cardiac muscle tissue developmentGO:005502630.014
small gtpase mediated signal transductionGO:0007264360.014
regulation of cytokine biosynthetic processGO:004203530.014
monocarboxylic acid transportGO:0015718520.014
negative regulation of cell deathGO:00605482290.014
anion transportGO:00068201780.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
reactive oxygen species metabolic processGO:0072593370.014
negative regulation of organ growthGO:004662130.014
cation homeostasisGO:00550801950.014
cellular calcium ion homeostasisGO:00068741600.014
pyridine containing compound metabolic processGO:0072524320.014
Rat
regulation of blood circulationGO:19035221100.014
negative regulation of protein metabolic processGO:00512481140.014
negative regulation of innate immune responseGO:004582440.014
reactive nitrogen species metabolic processGO:200105710.014
amide transportGO:00428861050.014
Rat
regulation of cell developmentGO:00602842630.013
nucleoside triphosphate catabolic processGO:00091431230.013
embryonic pattern specificationGO:000988010.013
secondary metabolic processGO:0019748150.013
regulation of homotypic cell cell adhesionGO:003411040.013
positive regulation of defense responseGO:0031349370.013
muscle system processGO:00030121150.013
regulation of phosphate metabolic processGO:00192203490.013
regulation of blood coagulationGO:003019390.013
steroid metabolic processGO:0008202730.013
purine nucleotide metabolic processGO:00061632290.013
signal releaseGO:00230611450.013
Rat
regulation of hormone secretionGO:00468831060.013
Rat
vascular process in circulatory systemGO:0003018960.013
carbohydrate biosynthetic processGO:0016051420.013
cellular protein localizationGO:00346131220.013
diterpenoid metabolic processGO:0016101330.013
carboxylic acid transportGO:00469421150.013
behaviorGO:00076102050.013
neural crest cell differentiationGO:001403320.013
tissue developmentGO:00098882520.013
macromolecule localizationGO:00330362520.013
response to calcium ionGO:0051592590.013
regulation of stem cell differentiationGO:200073620.013
negative regulation of molecular functionGO:00440921330.013
halogenated hydrocarbon metabolic processGO:004219740.013
cellular component movementGO:00069282480.013
positive regulation of cell developmentGO:00107201760.013
nicotine metabolic processGO:001893310.013
regulation of telomerase activityGO:005197220.013
positive regulation of molecular functionGO:00440932300.012
ribonucleoside catabolic processGO:00424541260.012
monovalent inorganic cation transportGO:00156721720.012
inflammatory responseGO:00069541500.012
decidualizationGO:0046697140.012
phenol containing compound biosynthetic processGO:004618990.012
sulfur compound metabolic processGO:0006790700.012
response to insulinGO:00328681330.012
Human
regulation of cellular localizationGO:00603412630.012
Rat
cardiac conductionGO:006133720.012
macromolecule catabolic processGO:0009057580.012
carboxylic acid biosynthetic processGO:0046394830.012
regulation of apoptotic processGO:00429813350.012
response to ethanolGO:00454711620.012
cellular response to xenobiotic stimulusGO:0071466190.012
negative regulation of developmental processGO:00510931250.012
cellular glucose homeostasisGO:0001678660.012
Rat
regulation of growthGO:00400081050.012
negative regulation of catalytic activityGO:00430861030.012
transmission of nerve impulseGO:0019226420.012
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.012
regulation of peptide hormone secretionGO:0090276800.012
Rat
response to mineralocorticoidGO:0051385490.011
proteolysisGO:00065081750.011
myelinationGO:0042552390.011
unsaturated fatty acid metabolic processGO:0033559390.011
purine ribonucleotide metabolic processGO:00091502270.011
muscle structure developmentGO:0061061870.011
lipid localizationGO:0010876620.011
negative regulation of growthGO:0045926370.011
defense response to gram negative bacteriumGO:005082930.011
cellular response to glucose stimulusGO:0071333650.011
Rat
response to decreased oxygen levelsGO:00362932370.011
regulation of catalytic activityGO:00507903040.011
negative regulation of mitotic cell cycle phase transitionGO:190199130.011
positive regulation of peptide hormone secretionGO:0090277500.011
Rat
positive regulation of cellular catabolic processGO:0031331710.011
tube developmentGO:0035295890.011
secretion by cellGO:00329402480.011
Rat
vitamin biosynthetic processGO:000911030.011
response to insecticideGO:0017085210.011
protein tetramerizationGO:0051262380.011
male gamete generationGO:0048232990.011
regulation of programmed cell deathGO:00430673410.011
bile acid biosynthetic processGO:000669930.011
fatty acid oxidationGO:0019395290.011
protein transportGO:00150311320.011
response to low density lipoprotein particleGO:005509840.011
renal system processGO:0003014400.011
negative regulation of synaptic transmission dopaminergicGO:003222740.011
ribonucleotide catabolic processGO:00092611360.011
cellular response to oxygen levelsGO:0071453600.011
regulation of protein modification processGO:00313991940.011
positive regulation of phosphorus metabolic processGO:00105622620.011
negative regulation of fibrinolysisGO:005191820.011
monocarboxylic acid biosynthetic processGO:0072330480.011
positive regulation of protein phosphorylationGO:00019341350.011
negative regulation of wound healingGO:006104580.011
positive regulation of hemostasisGO:190004840.011
tetrahydrofolate metabolic processGO:004665390.011
positive regulation of blood circulationGO:1903524650.011
single organism cell adhesionGO:0098602460.011
ribonucleotide metabolic processGO:00092592310.011
reproductive structure developmentGO:00486081280.011
nucleotide metabolic processGO:00091172790.011
Rat
regulation of phagocytosis engulfmentGO:006009940.011
ribonucleoside monophosphate metabolic processGO:0009161880.010
neurotransmitter uptakeGO:000150430.010
developmental growthGO:00485891000.010
alpha amino acid biosynthetic processGO:1901607230.010
regulation of hemostasisGO:190004690.010
multicellular organismal signalingGO:0035637440.010
sexual reproductionGO:00199531480.010
negative regulation of cell communicationGO:00106481580.010
cellular lipid catabolic processGO:0044242370.010
negative regulation of macromolecule metabolic processGO:00106052600.010
anatomical structure morphogenesisGO:00096532980.010
fat soluble vitamin biosynthetic processGO:004236220.010
purine ribonucleoside catabolic processGO:00461301240.010
divalent metal ion transportGO:00708381320.010
programmed cell deathGO:00125013920.010
meiotic cell cycle processGO:190304630.010
gamete generationGO:00072761240.010
response to corticosteroneGO:0051412400.010
regulation of monooxygenase activityGO:003276880.010
metal ion homeostasisGO:00550651860.010
regulation of synaptic transmission gabaergicGO:0032228170.010
heart developmentGO:0007507720.010
ribonucleoside triphosphate catabolic processGO:00092031220.010
sodium ion transportGO:0006814820.010
regulation of cell differentiationGO:00455953200.010

Pck1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.121
nutrition diseaseDOID:37400.054
acquired metabolic diseaseDOID:006015800.054
obesityDOID:997000.054
overnutritionDOID:65400.054
inherited metabolic disorderDOID:65500.028
disease of anatomical entityDOID:700.027
urinary system diseaseDOID:1800.027
kidney diseaseDOID:55700.021
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.018
connective tissue diseaseDOID:6500.014
sensory system diseaseDOID:005015500.011