Rattus norvegicus

0 known processes

Hlf

hepatic leukemia factor

Hlf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of multicellular organismal processGO:00512403870.437
regulation of rna biosynthetic processGO:20011413810.331
response to glucocorticoidGO:00513842230.217
developmental process involved in reproductionGO:00030061590.202
positive regulation of biosynthetic processGO:00098913190.193
reproductive processGO:00224143720.181
cell projection organizationGO:00300303020.172
cellular ketone metabolic processGO:0042180510.152
carboxylic acid metabolic processGO:00197522890.152
regulation of cell differentiationGO:00455953200.151
transcription dna templatedGO:00063513770.149
single organism reproductive processGO:00447022970.143
negative regulation of nitrogen compound metabolic processGO:00511721610.126
reproductive system developmentGO:00614581280.119
positive regulation of rna metabolic processGO:00512542030.110
organic acid metabolic processGO:00060822920.109
positive regulation of nitrogen compound metabolic processGO:00511733340.108
regulation of programmed cell deathGO:00430673410.108
positive regulation of rna biosynthetic processGO:19026801970.106
response to peptideGO:19016522920.106
positive regulation of nucleobase containing compound metabolic processGO:00459353190.103
regulation of system processGO:00440572080.102
positive regulation of phosphate metabolic processGO:00459372620.098
response to estradiolGO:00323551640.092
central nervous system developmentGO:00074173110.092
transmembrane transportGO:00550854120.091
response to alkaloidGO:00432791320.091
regulation of cell projection organizationGO:00313441750.089
brain developmentGO:00074202470.089
macromolecule localizationGO:00330362520.089
reproductive structure developmentGO:00486081280.086
positive regulation of transcription dna templatedGO:00458931970.085
regulation of molecular functionGO:00650093980.084
multicellular organism reproductionGO:00325042330.082
regulation of catalytic activityGO:00507903040.082
response to inorganic substanceGO:00100353770.081
regulation of transcription dna templatedGO:00063553740.080
transcription from rna polymerase ii promoterGO:00063662520.077
cellular amino acid metabolic processGO:00065201070.076
positive regulation of nucleic acid templated transcriptionGO:19035081970.075
positive regulation of gene expressionGO:00106282440.075
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.075
regulation of multicellular organismal developmentGO:20000263760.073
multi organism reproductive processGO:00447032620.070
cellular protein localizationGO:00346131220.070
positive regulation of cellular biosynthetic processGO:00313282950.068
oxoacid metabolic processGO:00434362900.068
regulation of nervous system developmentGO:00519602640.067
response to extracellular stimulusGO:00099913800.066
regulation of neuron projection developmentGO:00109751610.066
development of primary sexual characteristicsGO:00451371070.066
store operated calcium entryGO:000211520.065
reproductionGO:00000032450.064
rna metabolic processGO:00160704060.063
positive regulation of macromolecule biosynthetic processGO:00105572470.063
regulation of phosphorylationGO:00423252480.062
neuron differentiationGO:00301823680.058
positive regulation of synaptic transmissionGO:0050806620.056
cellular response to organonitrogen compoundGO:00714171970.056
cardiac chamber developmentGO:000320510.056
neurological system processGO:00508772190.055
negative regulation of apoptotic processGO:00430661810.055
regulation of rna metabolic processGO:00512523910.054
cellular response to stressGO:00335542690.054
sexual reproductionGO:00199531480.053
cellular response to endogenous stimulusGO:00714953770.053
male sex differentiationGO:0046661640.052
head developmentGO:00603222470.052
nucleic acid templated transcriptionGO:00976593790.050
response to peptide hormoneGO:00434342780.050
nitrogen compound transportGO:00717052290.050
carboxylic acid biosynthetic processGO:0046394830.049
cell cell signalingGO:00072673350.049
regulation of transcription from rna polymerase ii promoterGO:00063572340.049
positive regulation of nervous system developmentGO:00519621780.049
regulation of signal transductionGO:00099663180.048
gonad developmentGO:00084061040.048
rna biosynthetic processGO:00327743800.048
cellular component assemblyGO:00226073600.048
regulation of cell developmentGO:00602842630.047
response to tumor necrosis factorGO:0034612560.047
programmed cell deathGO:00125013920.047
negative regulation of cellular biosynthetic processGO:00313271610.046
negative regulation of signalingGO:00230571570.046
negative regulation of gene expressionGO:00106291990.046
negative regulation of cell deathGO:00605482290.046
organic acid biosynthetic processGO:0016053830.045
cellular response to hormone stimulusGO:00328702470.044
single organism behaviorGO:00447081300.043
apoptotic processGO:00069153810.043
regulation of apoptotic processGO:00429813350.042
intracellular transportGO:00469071850.042
sex differentiationGO:00075481130.041
response to corticosteroidGO:00319602350.041
protein phosphorylationGO:00064683450.041
positive regulation of secretionGO:00510471400.041
positive regulation of cell differentiationGO:00455972170.041
positive regulation of cellular component organizationGO:00511302000.041
macromolecular complex assemblyGO:00650032730.041
regulation of cellular ketone metabolic processGO:0010565270.040
regulation of intracellular signal transductionGO:19025312180.040
cellular response to oxygen containing compoundGO:19017013860.040
regulation of protein localizationGO:0032880810.040
cellular response to peptide hormone stimulusGO:00713751200.040
regulation of neuron differentiationGO:00456642080.040
regulation of lipid metabolic processGO:0019216680.039
multicellular organismal reproductive processGO:00486092330.039
regulation of cell cycleGO:0051726730.039
positive regulation of molecular functionGO:00440932300.039
regulation of cytokine productionGO:0001817560.039
cellular catabolic processGO:00442482950.038
positive regulation of peptide secretionGO:0002793520.038
carboxylic acid transportGO:00469421150.038
hormone transportGO:00099141210.037
cellular response to peptideGO:19016531330.037
response to toxic substanceGO:00096361330.037
response to radiationGO:00093141370.037
regulation of phosphate metabolic processGO:00192203490.036
neuron developmentGO:00486662860.036
cellular response to insulin stimulusGO:0032869810.036
intracellular receptor signaling pathwayGO:0030522350.035
heart morphogenesisGO:000300730.035
negative regulation of cell communicationGO:00106481580.035
negative regulation of metabolic processGO:00098923310.035
organic acid transportGO:00158491160.035
regulation of systemic arterial blood pressureGO:0003073300.035
regulation of secretion by cellGO:19035302080.035
regulation of cellular amino acid metabolic processGO:000652120.034
regulation of cellular localizationGO:00603412630.034
organelle organizationGO:00069962660.034
secretionGO:00469033070.034
regulation of cellular component organizationGO:00511283680.034
multi multicellular organism processGO:00447061380.033
response to reactive oxygen speciesGO:00003021200.033
cellular response to organic cyclic compoundGO:00714072020.033
protein complex subunit organizationGO:00718223020.033
response to insulinGO:00328681330.033
metal ion transportGO:00300012890.033
positive regulation of protein transportGO:0051222410.033
regulation of protein modification processGO:00313991940.032
protein complex biogenesisGO:00702712630.032
tube developmentGO:0035295890.032
negative regulation of cellular metabolic processGO:00313242810.032
regulation of neurogenesisGO:00507672470.032
protein transportGO:00150311320.032
negative regulation of macromolecule metabolic processGO:00106052600.031
cellular response to cytokine stimulusGO:00713451270.031
lipid metabolic processGO:00066292830.031
positive regulation of cell communicationGO:00106472710.031
response to hexoseGO:00097461440.030
cellular response to nitrogen compoundGO:19016992100.030
positive regulation of developmental processGO:00510942830.030
negative regulation of nucleic acid templated transcriptionGO:19035071170.030
negative regulation of programmed cell deathGO:00430691830.030
negative regulation of nucleobase containing compound metabolic processGO:00459341530.030
response to ethanolGO:00454711620.030
male gonad developmentGO:0008584590.029
response to decreased oxygen levelsGO:00362932370.029
single organism organelle organizationGO:19025891800.029
positive regulation of neurogenesisGO:00507691650.028
negative regulation of transcription dna templatedGO:00458921160.028
anatomical structure morphogenesisGO:00096532980.028
positive regulation of intracellular signal transductionGO:19025331380.028
regulation of secretionGO:00510462240.027
cellular amine metabolic processGO:0044106380.027
synaptic growth at neuromuscular junctionGO:005112410.027
forebrain developmentGO:0030900980.027
response to nutrient levelsGO:00316673700.027
positive regulation of transportGO:00510502450.027
regulation of hormone levelsGO:00108171870.027
female mating behaviorGO:006018060.027
g protein coupled acetylcholine receptor signaling pathwayGO:000721350.026
positive regulation of secretion by cellGO:19035321280.026
gamete generationGO:00072761240.026
secretion by cellGO:00329402480.026
glycosyl compound metabolic processGO:19016571820.026
cellular response to lipidGO:00713962010.026
cellular component morphogenesisGO:00329891550.026
negative regulation of rna biosynthetic processGO:19026791180.025
response to cytokineGO:00340972150.025
response to oxidative stressGO:00069791860.025
positive regulation of phosphorus metabolic processGO:00105622620.025
negative regulation of neurogenesisGO:0050768780.025
proteolysisGO:00065081750.025
positive regulation of catalytic activityGO:00430851840.024
purine containing compound metabolic processGO:00725212530.024
cardiac ventricle developmentGO:000323110.024
diencephalon developmentGO:0021536210.024
regulation of phosphorus metabolic processGO:00511743490.024
nephric duct developmentGO:007217610.023
response to growth factorGO:00708481890.023
protein localizationGO:00081041910.023
intracellular signal transductionGO:00355563140.023
response to transition metal nanoparticleGO:19902671220.023
sympathetic nervous system developmentGO:004848510.023
regulation of hydrolase activityGO:00513361430.022
muscle contractionGO:0006936880.022
small gtpase mediated signal transductionGO:0007264360.022
negative regulation of molecular functionGO:00440921330.022
cellular response to tumor necrosis factorGO:0071356460.022
l glutamate importGO:005193820.022
nucleoside triphosphate metabolic processGO:00091411440.022
cellular lipid metabolic processGO:00442552080.022
development of primary male sexual characteristicsGO:0046546590.021
cell type specific apoptotic processGO:00972851340.021
cellular component movementGO:00069282480.021
response to acid chemicalGO:00011012220.021
nucleoside metabolic processGO:00091161790.021
positive regulation of protein metabolic processGO:00512471780.021
metanephric comma shaped body morphogenesisGO:007227820.021
establishment of protein localizationGO:00451841410.021
response to glucoseGO:00097491360.021
regulation of nucleic acid templated transcriptionGO:19035063800.021
axonogenesisGO:0007409710.021
multicellular organism growthGO:003526410.021
comma shaped body morphogenesisGO:007204920.021
positive regulation of long term synaptic potentiationGO:190027340.020
regulation of protein phosphorylationGO:00019321830.020
n methyl d aspartate receptor clusteringGO:009711420.020
positive regulation of cellular protein metabolic processGO:00322701670.020
regulation of kinase activityGO:00435491170.020
peptide biosynthetic processGO:004304330.020
protein homooligomerizationGO:0051260910.020
purine nucleoside metabolic processGO:00422781690.019
organonitrogen compound biosynthetic processGO:19015661670.019
purine nucleoside catabolic processGO:00061521240.019
nucleoside monophosphate metabolic processGO:0009123930.019
axon developmentGO:0061564960.019
synapse organizationGO:0050808460.019
hormone metabolic processGO:0042445690.019
response to metal ionGO:00100382530.019
positive regulation of cell developmentGO:00107201760.019
regulation of acrosome reactionGO:006004610.019
sensory perception of painGO:0019233730.019
protein complex assemblyGO:00064612630.019
cellular component biogenesisGO:00440853680.019
motor neuron axon guidanceGO:000804510.019
neurotransmitter gated ion channel clusteringGO:007257830.018
neuron projection developmentGO:00311752730.018
leydig cell differentiationGO:003332780.018
negative regulation of response to stimulusGO:00485851550.018
fatty acid metabolic processGO:0006631990.018
amine metabolic processGO:0009308380.018
telencephalon developmentGO:0021537620.018
spermatogenesisGO:0007283990.018
negative regulation of intracellular estrogen receptor signaling pathwayGO:003314720.018
muscle structure developmentGO:0061061870.018
inorganic cation transmembrane transportGO:00986622020.018
gliogenesisGO:0042063930.017
protein maturationGO:0051604680.017
cardiac muscle cell contractionGO:0086003100.017
negative regulation of signal transductionGO:0009968830.017
grooming behaviorGO:000762540.017
cellular carbohydrate metabolic processGO:0044262720.017
regulation of protein transportGO:0051223680.017
negative regulation of rna metabolic processGO:00512531230.017
purine ribonucleoside metabolic processGO:00461281680.017
nucleobase containing small molecule metabolic processGO:00550863160.017
carbohydrate derivative metabolic processGO:19011353460.017
hormone secretionGO:00468791150.017
cellular response to abiotic stimulusGO:0071214850.017
tissue developmentGO:00098882520.016
positive regulation of cellular amine metabolic processGO:003324030.016
response to oxygen levelsGO:00704822650.016
purine ribonucleoside monophosphate metabolic processGO:0009167840.016
regulation of protein metabolic processGO:00512462890.016
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.016
regulation of ion transmembrane transportGO:00347651210.016
regulation of cellular amine metabolic processGO:003323880.016
regulation of cellular catabolic processGO:00313291010.016
regulation of cellular protein metabolic processGO:00322682670.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
regulation of cell growthGO:0001558850.015
regulation of embryonic developmentGO:004599520.015
defense responseGO:00069521940.015
actin filament based processGO:0030029860.015
hematopoietic progenitor cell differentiationGO:000224420.015
circadian rhythmGO:0007623880.015
response to vitamin eGO:0033197240.015
circulatory system processGO:00030131830.015
response to temperature stimulusGO:0009266940.015
positive regulation of cellular catabolic processGO:0031331710.015
dendrite developmentGO:0016358720.015
developmental growthGO:00485891000.015
heart processGO:0003015570.015
heart developmentGO:0007507720.015
metanephric s shaped body morphogenesisGO:007228420.015
chemosensory behaviorGO:000763520.015
response to carbohydrateGO:00097431830.015
interleukin 6 productionGO:0032635120.015
response to interleukin 1GO:0070555550.015
regulation of sensory perceptionGO:0051931290.014
positive regulation of cell projection organizationGO:00313461110.014
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.014
response to transforming growth factor betaGO:0071559460.014
protein oligomerizationGO:00512591910.014
gastrulationGO:000736920.014
locomotory exploration behaviorGO:003564110.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
monocarboxylic acid metabolic processGO:00327871520.014
insulin secretionGO:0030073690.014
cytoplasmic transportGO:00164821150.014
small molecule biosynthetic processGO:00442831240.014
negative regulation of developmental processGO:00510931250.014
single organism biosynthetic processGO:00447113420.014
leukocyte differentiationGO:0002521300.014
cell morphogenesisGO:00009021420.014
olfactory behaviorGO:004204820.014
axon midline choice point recognitionGO:001619920.014
regulation of muscle contractionGO:0006937530.014
positive regulation of lipid kinase activityGO:009021820.014
nucleoside triphosphate catabolic processGO:00091431230.014
sensory perceptionGO:00076001010.014
cellular response to hexose stimulusGO:0071331650.014
icosanoid metabolic processGO:0006690380.014
c21 steroid hormone biosynthetic processGO:0006700100.013
muscle tissue morphogenesisGO:006041510.013
cellular macromolecule localizationGO:00707271220.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
antral ovarian follicle growthGO:000154730.013
cell growthGO:00160491040.013
ion transmembrane transportGO:00342203650.013
cellular response to oxidative stressGO:0034599760.013
positive regulation of phosphorylationGO:00423271770.013
male gamete generationGO:0048232990.013
positive regulation of neuron differentiationGO:00456661260.013
negative regulation of cell differentiationGO:0045596990.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.013
nucleotide metabolic processGO:00091172790.013
locomotionGO:00400112370.013
developmental growth involved in morphogenesisGO:0060560330.013
peptide secretionGO:0002790860.013
fertilizationGO:000956630.013
response to estrogenGO:00436272320.013
cell projection morphogenesisGO:00488581230.013
regulation of axonogenesisGO:0050770370.013
nucleoside phosphate metabolic processGO:00067532830.013
female pregnancyGO:00075651220.013
carbohydrate derivative catabolic processGO:19011361470.012
metanephric part of ureteric bud developmentGO:003550210.012
purine nucleotide metabolic processGO:00061632290.012
growthGO:00400071650.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
atp metabolic processGO:0046034720.012
regulation of nephron tubule epithelial cell differentiationGO:007218210.012
negative regulation of cell developmentGO:0010721820.012
response to monosaccharideGO:00342841590.012
regulation of blood pressureGO:0008217830.012
response to ketoneGO:19016541820.012
cellular response to reactive oxygen speciesGO:0034614550.012
embryo developmentGO:0009790490.012
negative regulation of calcium ion importGO:009028120.012
locomotor rhythmGO:004547510.012
regulation of peptide secretionGO:0002791820.012
odontogenesisGO:0042476320.012
cellular response to carbohydrate stimulusGO:0071322720.012
vasoconstrictionGO:0042310540.012
negative regulation of protein metabolic processGO:00512481140.012
negative regulation of neuron differentiationGO:0045665620.012
potassium ion transportGO:0006813970.012
response to ionizing radiationGO:0010212590.012
glial cell differentiationGO:0010001650.012
cytokine productionGO:0001816610.012
response to herbicideGO:0009635160.012
regulation of sensory perception of painGO:0051930290.012
blood circulationGO:00080151830.011
cell morphogenesis involved in differentiationGO:00009041190.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
mapk cascadeGO:00001651400.011
positive regulation of transferase activityGO:0051347810.011
ribonucleoside metabolic processGO:00091191740.011
purine ribonucleotide metabolic processGO:00091502270.011
macromolecular complex subunit organizationGO:00439333390.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
peptide hormone secretionGO:0030072840.011
nucleobase containing compound catabolic processGO:00346551520.011
lipid biosynthetic processGO:00086101280.011
positive regulation of protein modification processGO:00314011420.011
reactive nitrogen species metabolic processGO:200105710.011
adult locomotory behaviorGO:000834440.011
purine containing compound biosynthetic processGO:0072522850.011
cellular response to external stimulusGO:00714961180.011
negative regulation of uterine smooth muscle contractionGO:007047320.011
actin cytoskeleton organizationGO:0030036730.011
positive regulation of ruffle assemblyGO:190002910.011
olfactory bulb interneuron differentiationGO:002188910.011
cation transportGO:00068123820.011
regulation of establishment of protein localizationGO:0070201690.011
positive regulation of cell proliferationGO:00082842490.011
cell activationGO:0001775970.011
synaptic transmissionGO:00072682350.011
response to nicotineGO:0035094510.011
carbohydrate homeostasisGO:0033500750.011
reproductive behaviorGO:0019098100.011
response to nutrientGO:00075842480.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
cellular response to extracellular stimulusGO:0031668730.011
regulation of insulin secretionGO:0050796650.011
oxidation reduction processGO:00551143040.011
reactive oxygen species biosynthetic processGO:190340980.011
excretionGO:0007588240.011
autonomic nervous system developmentGO:004848330.011
muscle organ morphogenesisGO:004864410.010
organic substance catabolic processGO:19015753160.010
negative regulation of biosynthetic processGO:00098901680.010
ras protein signal transductionGO:0007265290.010
regulation of cell proliferationGO:00421273590.010
positive regulation of neuron migrationGO:200122420.010
glucose homeostasisGO:0042593750.010
respiratory gaseous exchangeGO:000758540.010
behavioral response to ethanolGO:004814910.010
neuron neuron synaptic transmissionGO:0007270600.010
purine ribonucleoside triphosphate metabolic processGO:00092051400.010
axon choice point recognitionGO:001619820.010
morphogenesis of embryonic epitheliumGO:001633130.010
axis specificationGO:000979840.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
nucleoside catabolic processGO:00091641260.010
regulation of interferon gamma productionGO:003264930.010
positive regulation of lipid metabolic processGO:0045834330.010
positive regulation of mapk cascadeGO:0043410920.010
response to starvationGO:0042594590.010
positive regulation of kinase activityGO:0033674770.010
energy derivation by oxidation of organic compoundsGO:0015980460.010

Hlf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.029
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.028
urinary system diseaseDOID:1800.026
central nervous system diseaseDOID:33100.013
epilepsy syndromeDOID:182600.013
brain diseaseDOID:93600.013
kidney diseaseDOID:55700.012
connective tissue diseaseDOID:6500.012