Rattus norvegicus

0 known processes

Ap2a1

adaptor-related protein complex 2, alpha 1 subunit

Ap2a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic vesicle endocytosisGO:004848840.894
vesicle mediated transportGO:00161921810.417
endocytosisGO:0006897840.285
cell cell signalingGO:00072673350.180
nucleotide metabolic processGO:00091172790.172
purine ribonucleotide catabolic processGO:00091541360.171
purine ribonucleoside triphosphate metabolic processGO:00092051400.159
synaptic vesicle recyclingGO:003646550.158
macromolecule localizationGO:00330362520.157
nucleoside catabolic processGO:00091641260.154
organelle organizationGO:00069962660.151
nucleoside triphosphate catabolic processGO:00091431230.140
response to heatGO:0009408600.133
purine nucleoside triphosphate metabolic processGO:00091441410.132
regulation of cellular component organizationGO:00511283680.130
purine nucleoside triphosphate catabolic processGO:00091461220.126
cellular catabolic processGO:00442482950.125
carbohydrate derivative metabolic processGO:19011353460.122
nucleobase containing small molecule metabolic processGO:00550863160.120
glycosyl compound metabolic processGO:19016571820.119
purine ribonucleotide metabolic processGO:00091502270.119
olfactory learningGO:000835510.117
protein localizationGO:00081041910.114
ribonucleoside triphosphate catabolic processGO:00092031220.113
nucleoside triphosphate metabolic processGO:00091411440.112
single organism behaviorGO:00447081300.111
ribonucleotide metabolic processGO:00092592310.110
organophosphate metabolic processGO:00196373700.109
purine containing compound metabolic processGO:00725212530.108
ribose phosphate metabolic processGO:00196932350.108
nucleotide catabolic processGO:00091661390.107
carbohydrate derivative catabolic processGO:19011361470.107
purine containing compound catabolic processGO:00725231380.102
cellular component assemblyGO:00226073600.100
purine nucleotide catabolic processGO:00061951360.098
salivary gland morphogenesisGO:000743510.098
purine nucleoside metabolic processGO:00422781690.098
purine ribonucleoside metabolic processGO:00461281680.097
gland developmentGO:00487321550.093
organic cyclic compound catabolic processGO:19013611750.091
gtp catabolic processGO:0006184710.090
vesicle localizationGO:0051648330.090
aromatic compound catabolic processGO:00194391680.089
ribonucleotide catabolic processGO:00092611360.088
catabolic processGO:00090563510.087
ribonucleoside triphosphate metabolic processGO:00091991410.087
nucleoside metabolic processGO:00091161790.087
nucleoside phosphate metabolic processGO:00067532830.085
nucleoside phosphate catabolic processGO:19012921400.084
macromolecular complex assemblyGO:00650032730.079
glycosyl compound catabolic processGO:19016581260.078
nucleobase containing compound catabolic processGO:00346551520.076
learning or memoryGO:0007611900.075
guanosine containing compound metabolic processGO:1901068740.074
cellular component biogenesisGO:00440853680.072
purine ribonucleoside triphosphate catabolic processGO:00092071220.072
ribonucleoside metabolic processGO:00091191740.072
purine nucleoside catabolic processGO:00061521240.072
vesicle organizationGO:0016050290.072
heterocycle catabolic processGO:00467001670.070
synaptic transmissionGO:00072682350.070
organic substance catabolic processGO:19015753160.069
positive regulation of response to stimulusGO:00485842850.068
guanosine containing compound catabolic processGO:1901069710.067
membrane organizationGO:0061024940.066
regulation of neurogenesisGO:00507672470.066
positive regulation of signal transductionGO:00099671750.066
response to nutrientGO:00075842480.064
positive regulation of signalingGO:00230562700.064
cell cycleGO:00070491010.063
positive regulation of catalytic activityGO:00430851840.062
purine ribonucleoside catabolic processGO:00461301240.061
regulation of multicellular organismal developmentGO:20000263760.061
single organism catabolic processGO:00447122830.060
response to extracellular stimulusGO:00099913800.060
positive regulation of nervous system developmentGO:00519621780.060
chemosensory behaviorGO:000763520.059
cell junction maintenanceGO:003433110.059
response to nutrient levelsGO:00316673700.059
synaptic vesicle localizationGO:0097479240.059
organophosphate catabolic processGO:00464341480.058
anatomical structure morphogenesisGO:00096532980.058
positive regulation of phosphate metabolic processGO:00459372620.057
organonitrogen compound catabolic processGO:19015651790.056
regulation of phosphate metabolic processGO:00192203490.056
macromolecular complex subunit organizationGO:00439333390.055
cell projection organizationGO:00300303020.054
regulation of cell developmentGO:00602842630.054
learningGO:0007612330.053
establishment of organelle localizationGO:0051656370.053
positive regulation of neurogenesisGO:00507691650.053
feeding behaviorGO:0007631530.052
synapse organizationGO:0050808460.052
programmed cell deathGO:00125013920.052
regulation of cell differentiationGO:00455953200.052
multi organism reproductive processGO:00447032620.051
morphogenesis of a polarized epitheliumGO:000173810.051
organelle localizationGO:0051640550.049
apoptotic processGO:00069153810.049
salivary gland developmentGO:000743130.048
establishment of vesicle localizationGO:0051650310.047
positive regulation of nitrogen compound metabolic processGO:00511733340.047
reproductive processGO:00224143720.047
positive regulation of cell differentiationGO:00455972170.047
positive regulation of phosphorus metabolic processGO:00105622620.046
establishment of synaptic vesicle localizationGO:0097480230.046
regulation of nervous system developmentGO:00519602640.045
positive regulation of nucleobase containing compound metabolic processGO:00459353190.044
protein complex assemblyGO:00064612630.044
response to temperature stimulusGO:0009266940.044
positive regulation of developmental processGO:00510942830.043
single organism organelle organizationGO:19025891800.043
synaptic vesicle transportGO:0048489230.041
receptor metabolic processGO:0043112180.040
regulation of apoptotic processGO:00429813350.039
cellular nitrogen compound catabolic processGO:00442701630.039
multicellular organismal reproductive processGO:00486092330.039
regulation of programmed cell deathGO:00430673410.038
positive regulation of molecular functionGO:00440932300.038
regulation of phosphorus metabolic processGO:00511743490.038
positive regulation of multicellular organismal processGO:00512403870.037
positive regulation of cell developmentGO:00107201760.037
cell junction organizationGO:0034330210.037
regulation of neuron differentiationGO:00456642080.036
protein phosphorylationGO:00064683450.036
cellular response to stressGO:00335542690.036
cytoskeleton dependent cytokinesisGO:006164020.036
cognitionGO:0050890920.036
response to peptideGO:19016522920.036
receptor internalizationGO:0031623140.035
regulation of synaptic transmissionGO:00508041410.035
regulation of cytoskeleton organizationGO:0051493490.034
regulation of signal transductionGO:00099663180.034
gtp metabolic processGO:0046039720.034
metal ion transportGO:00300012890.034
cellular component maintenanceGO:004395440.033
regulation of system processGO:00440572080.033
neuron differentiationGO:00301823680.033
regulation of cellular protein metabolic processGO:00322682670.033
growthGO:00400071650.033
conditioned taste aversionGO:000166120.032
synapse assemblyGO:0007416290.032
transcription dna templatedGO:00063513770.032
purine nucleotide metabolic processGO:00061632290.031
regulation of molecular functionGO:00650093980.031
negative regulation of cell deathGO:00605482290.031
transmembrane transportGO:00550854120.031
regulation of protein metabolic processGO:00512462890.031
single organism membrane organizationGO:0044802740.030
cellular amine metabolic processGO:0044106380.030
protein complex biogenesisGO:00702712630.030
establishment of protein localizationGO:00451841410.029
regulation of endocytosisGO:0030100420.029
memoryGO:0007613540.029
regulation of transcription dna templatedGO:00063553740.029
protein complex subunit organizationGO:00718223020.029
reproductionGO:00000032450.029
synaptic growth at neuromuscular junctionGO:005112410.029
ribonucleoside catabolic processGO:00424541260.028
rna biosynthetic processGO:00327743800.028
multicellular organism reproductionGO:00325042330.028
cell cycle processGO:0022402570.028
olfactory behaviorGO:004204820.028
cation transportGO:00068123820.028
positive regulation of gtpase activityGO:0043547470.027
amine metabolic processGO:0009308380.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
neurological system processGO:00508772190.026
positive regulation of transportGO:00510502450.025
secretionGO:00469033070.025
regulation of notch signaling pathwayGO:000859330.025
regulation of vesicle mediated transportGO:0060627810.025
cellular macromolecular complex assemblyGO:0034622580.025
neuron developmentGO:00486662860.025
oxoacid metabolic processGO:00434362900.025
regulation of cellular amine metabolic processGO:003323880.025
regulation of cellular amino acid metabolic processGO:000652120.025
brain developmentGO:00074202470.025
behaviorGO:00076102050.024
cell projection assemblyGO:0030031210.024
positive regulation of biosynthetic processGO:00098913190.024
negative regulation of macromolecule metabolic processGO:00106052600.024
transcription from rna polymerase ii promoterGO:00063662520.024
regulation of actin cytoskeleton organizationGO:0032956300.024
regulation of cell cycleGO:0051726730.024
positive regulation of protein phosphorylationGO:00019341350.023
small gtpase mediated signal transductionGO:0007264360.023
regulation of catalytic activityGO:00507903040.023
negative regulation of metabolic processGO:00098923310.023
regulation of purine nucleotide metabolic processGO:19005421150.023
negative regulation of programmed cell deathGO:00430691830.023
response to estrogenGO:00436272320.023
nucleic acid templated transcriptionGO:00976593790.023
positive regulation of cellular protein metabolic processGO:00322701670.022
receptor mediated endocytosisGO:0006898420.022
negative regulation of nitrogen compound metabolic processGO:00511721610.022
neuron projection developmentGO:00311752730.022
regulation of cellular ketone metabolic processGO:0010565270.022
signal releaseGO:00230611450.022
single organism reproductive processGO:00447022970.022
positive regulation of cellular biosynthetic processGO:00313282950.022
regulation of rna biosynthetic processGO:20011413810.022
cytoskeleton organizationGO:00070101110.021
rna metabolic processGO:00160704060.021
regulation of kinase activityGO:00435491170.021
positive regulation of rna biosynthetic processGO:19026801970.021
response to radiationGO:00093141370.021
central nervous system developmentGO:00074173110.021
negative regulation of cellular component organizationGO:0051129830.021
sexual reproductionGO:00199531480.021
extracellular matrix organizationGO:0030198130.021
gland morphogenesisGO:0022612120.021
positive regulation of cellular amino acid metabolic processGO:004576410.020
anatomical structure formation involved in morphogenesisGO:0048646830.020
positive regulation of gene expressionGO:00106282440.020
regulation of neuron deathGO:19012141150.020
adult locomotory behaviorGO:000834440.020
carboxylic acid metabolic processGO:00197522890.020
regulation of transferase activityGO:00513381230.020
secretion by cellGO:00329402480.020
positive regulation of cellular amine metabolic processGO:003324030.019
regulation of nucleic acid templated transcriptionGO:19035063800.019
developmental process involved in reproductionGO:00030061590.019
regulation of organelle organizationGO:0033043800.019
male gamete generationGO:0048232990.019
positive regulation of cellular component organizationGO:00511302000.019
positive regulation of rna metabolic processGO:00512542030.019
negative regulation of apoptotic processGO:00430661810.019
positive regulation of transferase activityGO:0051347810.019
negative regulation of cell communicationGO:00106481580.018
negative regulation of rna metabolic processGO:00512531230.018
positive regulation of phosphorylationGO:00423271770.018
cellular lipid metabolic processGO:00442552080.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
positive regulation of apoptotic processGO:00430651540.018
neurotransmitter transportGO:0006836420.018
regulation of phosphorylationGO:00423252480.018
negative regulation of biosynthetic processGO:00098901680.017
cellular ketone metabolic processGO:0042180510.017
positive regulation of cell deathGO:00109421840.017
positive regulation of protein modification processGO:00314011420.017
regulation of muscle system processGO:0090257790.017
cellular amino acid metabolic processGO:00065201070.017
negative regulation of cellular metabolic processGO:00313242810.017
organic acid metabolic processGO:00060822920.017
positive regulation of cell communicationGO:00106472710.017
blood circulationGO:00080151830.017
positive regulation of neuron differentiationGO:00456661260.017
regulation of synaptic plasticityGO:0048167700.017
regulation of protein kinase activityGO:00458591050.017
regulation of rna metabolic processGO:00512523910.017
carbohydrate metabolic processGO:00059751300.017
regulation of protein modification processGO:00313991940.017
ion homeostasisGO:00508012120.017
spermatogenesisGO:0007283990.017
positive regulation of protein metabolic processGO:00512471780.017
regulation of mrna splicing via spliceosomeGO:004802430.017
regulation of hydrolase activityGO:00513361430.017
negative regulation of gene expressionGO:00106291990.017
epithelium developmentGO:0060429960.016
cellular response to oxygen containing compoundGO:19017013860.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
positive regulation of cell proliferationGO:00082842490.016
positive regulation of nucleotide metabolic processGO:0045981910.016
protein oligomerizationGO:00512591910.016
negative regulation of cellular biosynthetic processGO:00313271610.016
response to cytokineGO:00340972150.016
positive regulation of gtp catabolic processGO:0033126480.016
intracellular signal transductionGO:00355563140.016
oxidation reduction processGO:00551143040.016
circulatory system processGO:00030131830.016
response to oxygen levelsGO:00704822650.016
negative regulation of multicellular organismal processGO:00512412030.016
negative regulation of macromolecule biosynthetic processGO:00105581480.015
regulation of gtpase activityGO:0043087570.015
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
neuron apoptotic processGO:0051402880.015
adherens junction organizationGO:0034332130.015
regulation of gtp catabolic processGO:0033124580.015
single organism biosynthetic processGO:00447113420.015
response to purine containing compoundGO:00140741260.015
lipid biosynthetic processGO:00086101280.015
endomembrane system organizationGO:0010256480.015
positive regulation of programmed cell deathGO:00430681570.015
positive regulation of purine nucleotide metabolic processGO:1900544910.015
regulation of cell proliferationGO:00421273590.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.015
organ morphogenesisGO:0009887750.015
response to ethanolGO:00454711620.014
response to corticosteroidGO:00319602350.014
homeostatic processGO:00425923310.014
response to insulinGO:00328681330.014
cellular response to external stimulusGO:00714961180.014
regulation of intracellular signal transductionGO:19025312180.014
regulation of neuronal synaptic plasticityGO:0048168310.014
negative regulation of protein metabolic processGO:00512481140.014
muscle system processGO:00030121150.014
negative regulation of neuron deathGO:1901215690.014
anterior posterior pattern specificationGO:000995210.014
cellular chemical homeostasisGO:00550822470.014
cell cell junction organizationGO:0045216200.014
regulation of nucleoside metabolic processGO:0009118660.014
regulation of nucleotide metabolic processGO:00061401170.014
regulation of purine nucleotide catabolic processGO:0033121650.014
regulation of nucleotide catabolic processGO:0030811650.014
positive regulation of transcription dna templatedGO:00458931970.014
lipid metabolic processGO:00066292830.014
cellular response to unfolded proteinGO:003462020.014
negative regulation of molecular functionGO:00440921330.014
rhythmic processGO:00485111560.014
positive regulation of hydrolase activityGO:0051345860.014
cellular component movementGO:00069282480.014
cellular response to cytokine stimulusGO:00713451270.014
negative regulation of transcription dna templatedGO:00458921160.014
cellular response to hormone stimulusGO:00328702470.013
regulation of growthGO:00400081050.013
positive regulation of cellular catabolic processGO:0031331710.013
actin cytoskeleton organizationGO:0030036730.013
acid secretionGO:0046717480.013
carbohydrate derivative biosynthetic processGO:19011371240.013
female pregnancyGO:00075651220.013
associative learningGO:0008306190.013
actin filament based processGO:0030029860.013
response to inorganic substanceGO:00100353770.013
response to estradiolGO:00323551640.013
negative regulation of cellular protein metabolic processGO:00322691060.013
response to bacteriumGO:00096172000.013
axis specificationGO:000979840.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
negative regulation of rna biosynthetic processGO:19026791180.013
gamete generationGO:00072761240.013
cellular protein complex assemblyGO:0043623440.013
chemical homeostasisGO:00488782920.013
lipid storageGO:001991510.013
response to decreased oxygen levelsGO:00362932370.013
cellular process involved in reproduction in multicellular organismGO:0022412350.013
cellular response to extracellular stimulusGO:0031668730.013
cell part morphogenesisGO:00329901230.013
positive regulation of immune system processGO:0002684900.013
positive regulation of intracellular signal transductionGO:19025331380.013
limb morphogenesisGO:003510840.013
negative regulation of neuron apoptotic processGO:0043524450.013
regulation of cellular catabolic processGO:00313291010.012
negative regulation of response to stimulusGO:00485851550.012
protein transportGO:00150311320.012
head developmentGO:00603222470.012
negative regulation of signalingGO:00230571570.012
regulation of cellular localizationGO:00603412630.012
regulation of protein phosphorylationGO:00019321830.012
ras protein signal transductionGO:0007265290.012
positive regulation of kinase activityGO:0033674770.012
cellular homeostasisGO:00197252520.012
peptidyl amino acid modificationGO:00181931260.012
cellular response to nitrogen compoundGO:19016992100.012
response to acid chemicalGO:00011012220.012
eye morphogenesisGO:004859240.012
gastrulationGO:000736920.012
negative regulation of natural killer cell mediated immunityGO:000271640.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
regulation of hormone levelsGO:00108171870.012
response to hypoxiaGO:00016662310.012
inorganic ion transmembrane transportGO:00986602290.012
response to peptide hormoneGO:00434342780.012
response to vitaminGO:00332731310.012
cellular protein localizationGO:00346131220.012
neuron neuron synaptic transmissionGO:0007270600.012
axon developmentGO:0061564960.011
single organism intracellular transportGO:19025821660.011
negative regulation of innate immune responseGO:004582440.011
regenerationGO:00310991630.011
monovalent inorganic cation transportGO:00156721720.011
positive regulation of cellular component movementGO:00512721020.011
regulation of muscle contractionGO:0006937530.011
response to woundingGO:00096112540.011
regulation of catabolic processGO:00098941130.011
muscle contractionGO:0006936880.011
cell motilityGO:00488702020.011
regulation of neuron apoptotic processGO:0043523830.011
localization of cellGO:00516742020.011
regulation of actin filament based processGO:0032970420.011
cell projection morphogenesisGO:00488581230.011
response to lipopolysaccharideGO:00324961910.011
embryonic pattern specificationGO:000988010.011
dna metabolic processGO:0006259960.011
organophosphate biosynthetic processGO:00904071430.011
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.011
cell morphogenesisGO:00009021420.011
locomotionGO:00400112370.011
cytoplasmic transportGO:00164821150.011
positive regulation of t cell mediated cytotoxicityGO:000191640.011
glial cell differentiationGO:0010001650.011
response to glucocorticoidGO:00513842230.011
g protein coupled receptor signaling pathwayGO:00071862420.011
divalent metal ion transportGO:00708381320.011
toxin transportGO:190199830.011
positive regulation of protein kinase activityGO:0045860730.011
neuron projection morphogenesisGO:00488121220.011
muscle structure developmentGO:0061061870.011
organic hydroxy compound metabolic processGO:19016151150.010
cortical actin cytoskeleton organizationGO:003086620.010
ribose phosphate biosynthetic processGO:0046390870.010
endoplasmic reticulum unfolded protein responseGO:003096820.010
neuromuscular processGO:005090520.010
negative regulation of transportGO:00510511360.010
regulation of ion transportGO:00432692450.010
membrane buddingGO:000690080.010
response to external biotic stimulusGO:00432072210.010
regulation of membrane potentialGO:00423911100.010
regulation of protein localizationGO:0032880810.010
response to oxidative stressGO:00069791860.010
regulation of secretion by cellGO:19035302080.010
cellular response to growth factor stimulusGO:00713631620.010
carboxylic acid transportGO:00469421150.010
embryonic limb morphogenesisGO:003032640.010
agingGO:00075682410.010

Ap2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.079
musculoskeletal system diseaseDOID:1700.079
myopathyDOID:42300.051
muscle tissue diseaseDOID:6600.051
muscular diseaseDOID:008000000.051
nervous system diseaseDOID:86300.026
disease of metabolismDOID:001466700.012
sensory system diseaseDOID:005015500.011
central nervous system diseaseDOID:33100.010