Rattus norvegicus

53 known processes

Mgp

matrix Gla protein

(Aliases: Mglap)

Mgp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to external biotic stimulusGO:00432072210.877
response to other organismGO:00517072200.848
response to biotic stimulusGO:00096072260.804
tissue developmentGO:00098882520.757
response to corticosteroidGO:00319602350.748
protein complex subunit organizationGO:00718223020.693
response to inorganic substanceGO:00100353770.658
macromolecular complex subunit organizationGO:00439333390.578
response to molecule of bacterial originGO:00022371940.515
regulation of multicellular organismal developmentGO:20000263760.463
programmed cell deathGO:00125013920.457
wound healingGO:00420601220.442
regulation of schwann cell migrationGO:190014720.361
response to glucocorticoidGO:00513842230.345
response to zinc ionGO:0010043390.341
Rat
response to transition metal nanoparticleGO:19902671220.337
Rat
response to nutrient levelsGO:00316673700.328
anatomical structure morphogenesisGO:00096532980.300
response to bacteriumGO:00096172000.293
regulation of cellular component organizationGO:00511283680.273
response to lipopolysaccharideGO:00324961910.265
eye developmentGO:0001654500.240
negative regulation of macromolecule metabolic processGO:00106052600.239
negative regulation of nitrogen compound metabolic processGO:00511721610.236
positive regulation of multicellular organismal processGO:00512403870.235
response to amino acidGO:0043200750.232
negative regulation of cell deathGO:00605482290.230
negative regulation of nucleobase containing compound metabolic processGO:00459341530.227
negative regulation of biosynthetic processGO:00098901680.222
astrocyte developmentGO:001400240.220
negative regulation of gene expressionGO:00106291990.208
chylomicron remodelingGO:003437110.208
reproductive processGO:00224143720.207
response to woundingGO:00096112540.202
regulation of cell proliferationGO:00421273590.201
negative regulation of viral entry into host cellGO:004659730.199
cell adhesionGO:00071551100.193
regulation of locomotionGO:00400121480.193
embryo implantationGO:0007566150.178
cellular response to endogenous stimulusGO:00714953770.177
defense responseGO:00069521940.176
response to growth factorGO:00708481890.174
Rat
multicellular organism reproductionGO:00325042330.172
blood coagulationGO:0007596260.170
lipid biosynthetic processGO:00086101280.169
coagulationGO:0050817280.166
negative regulation of metabolic processGO:00098923310.162
response to estradiolGO:00323551640.162
schwann cell migrationGO:003613520.161
response to antidepressantGO:003627640.158
cell morphogenesisGO:00009021420.157
protein complex assemblyGO:00064612630.155
response to oxygen levelsGO:00704822650.154
response to interferon alphaGO:003545510.154
response to decreased oxygen levelsGO:00362932370.150
regulation of cell differentiationGO:00455953200.148
single organism biosynthetic processGO:00447113420.147
agingGO:00075682410.146
Rat
response to estrogenGO:00436272320.144
Rat
negative regulation of rna metabolic processGO:00512531230.144
positive regulation of developmental processGO:00510942830.141
cellular response to growth factor stimulusGO:00713631620.138
Rat
regulation of viral transcriptionGO:004678220.138
single organism reproductive processGO:00447022970.136
regulation of viral entry into host cellGO:004659630.133
protein complex biogenesisGO:00702712630.133
negative regulation of multicellular organismal processGO:00512412030.131
growthGO:00400071650.129
response to nutrientGO:00075842480.128
negative regulation of rna biosynthetic processGO:19026791180.127
response to acid chemicalGO:00011012220.126
rna metabolic processGO:00160704060.126
circulatory system developmentGO:00723591340.124
response to monosaccharideGO:00342841590.124
macromolecular complex assemblyGO:00650032730.122
astrocyte differentiationGO:0048708190.120
negative regulation of cell differentiationGO:0045596990.117
biological adhesionGO:00226101100.117
cellular response to organic cyclic compoundGO:00714072020.113
Rat
negative regulation of developmental processGO:00510931250.112
developmental growthGO:00485891000.111
cardiovascular system developmentGO:00723581340.111
oxoacid metabolic processGO:00434362900.106
locomotionGO:00400112370.104
regulation of skeletal muscle cell differentiationGO:200101410.102
cell migrationGO:00164771970.099
urogenital system developmentGO:0001655780.099
galactolipid catabolic processGO:001937610.098
negative regulation of cellular biosynthetic processGO:00313271610.098
apoptotic processGO:00069153810.097
negative regulation of cellular metabolic processGO:00313242810.097
tissue regenerationGO:0042246360.096
cellular response to stressGO:00335542690.095
response to metal ionGO:00100382530.095
response to fibroblast growth factorGO:0071774290.094
inorganic ion transmembrane transportGO:00986602290.093
cell activationGO:0001775970.090
skeletal muscle tissue regenerationGO:0043403100.089
positive regulation of response to stimulusGO:00485842850.089
multi multicellular organism processGO:00447061380.089
positive regulation of voltage gated calcium channel activityGO:190138710.088
cellular response to lipidGO:00713962010.087
Rat
regulation of programmed cell deathGO:00430673410.086
response to interferon betaGO:003545610.086
multi organism reproductive processGO:00447032620.082
localization of cellGO:00516742020.080
response to hypoxiaGO:00016662310.079
regulation of catalytic activityGO:00507903040.078
rna biosynthetic processGO:00327743800.078
intermediate filament bundle assemblyGO:004511010.077
negative regulation of macromolecule biosynthetic processGO:00105581480.076
response to carbohydrateGO:00097431830.075
developmental process involved in reproductionGO:00030061590.074
positive regulation of gene expressionGO:00106282440.074
regulation of cell morphogenesisGO:0022604770.072
cellular catabolic processGO:00442482950.072
regulation of rna biosynthetic processGO:20011413810.071
response to radiationGO:00093141370.070
striated muscle tissue developmentGO:0014706580.070
regulation of transcription from rna polymerase ii promoterGO:00063572340.070
regulation of anatomical structure morphogenesisGO:00226031410.069
blood vessel developmentGO:0001568690.069
cellular component assemblyGO:00226073600.069
negative regulation of nucleic acid templated transcriptionGO:19035071170.067
carboxylic acid metabolic processGO:00197522890.064
sulfur compound metabolic processGO:0006790700.064
organic acid metabolic processGO:00060822920.063
regulation of response to stressGO:00801341260.063
multicellular organismal reproductive processGO:00486092330.063
placenta developmentGO:0001890220.063
protein oligomerizationGO:00512591910.063
cell projection organizationGO:00300303020.062
neuron developmentGO:00486662860.061
transcription from rna polymerase ii promoterGO:00063662520.060
response to hexoseGO:00097461440.059
neuron differentiationGO:00301823680.058
response to glucoseGO:00097491360.056
negative regulation of response to stimulusGO:00485851550.054
regulation of neurogenesisGO:00507672470.054
regulation of cell developmentGO:00602842630.053
cellular response to hormone stimulusGO:00328702470.053
lipid metabolic processGO:00066292830.052
cellular component movementGO:00069282480.051
regulation of nervous system developmentGO:00519602640.051
ras protein signal transductionGO:0007265290.050
positive regulation of nucleobase containing compound metabolic processGO:00459353190.050
response to peptide hormoneGO:00434342780.050
homeostatic processGO:00425923310.050
viral gene expressionGO:001908020.050
positive regulation of signalingGO:00230562700.050
catabolic processGO:00090563510.050
regulation of rna metabolic processGO:00512523910.049
negative regulation of innate immune responseGO:004582440.049
positive regulation of synaptic transmissionGO:0050806620.048
behaviorGO:00076102050.048
positive regulation of cellular biosynthetic processGO:00313282950.047
muscle structure developmentGO:0061061870.047
proteolysisGO:00065081750.047
response to peptideGO:19016522920.047
reproductive structure developmentGO:00486081280.047
regulation of calcium ion transmembrane transportGO:1903169180.046
positive regulation of neurogenesisGO:00507691650.046
positive regulation of cell differentiationGO:00455972170.046
response to vitaminGO:00332731310.046
Rat
chemical homeostasisGO:00488782920.046
vesicle mediated transportGO:00161921810.045
negative regulation of viral processGO:004852540.045
reactive oxygen species metabolic processGO:0072593370.045
regulation of nucleic acid templated transcriptionGO:19035063800.045
reproductive system developmentGO:00614581280.044
viral transcriptionGO:001908320.044
positive regulation of cellular component organizationGO:00511302000.044
regulation of neuron projection developmentGO:00109751610.043
positive regulation of nervous system developmentGO:00519621780.043
cyclic nucleotide metabolic processGO:0009187800.043
negative regulation of skeletal muscle cell differentiationGO:200101510.042
intracellular signal transductionGO:00355563140.042
muscle tissue developmentGO:0060537580.041
innate immune responseGO:0045087350.041
glial cell differentiationGO:0010001650.041
response to campGO:0051591910.041
positive regulation of response to external stimulusGO:0032103510.041
cellular response to glucocorticoid stimulusGO:0071385680.040
response to reactive oxygen speciesGO:00003021200.040
positive regulation of neuron differentiationGO:00456661260.040
female pregnancyGO:00075651220.039
regulation of body fluid levelsGO:0050878900.039
positive regulation of nitrogen compound metabolic processGO:00511733340.039
reproductionGO:00000032450.038
positive regulation of cell proliferationGO:00082842490.038
cellular component biogenesisGO:00440853680.038
positive regulation of catalytic activityGO:00430851840.038
cellular response to fibroblast growth factor stimulusGO:0044344240.038
non canonical wnt signaling pathwayGO:003556730.038
response to hydrogen peroxideGO:0042542890.037
regulation of phosphorus metabolic processGO:00511743490.037
carbohydrate derivative metabolic processGO:19011353460.037
response to extracellular stimulusGO:00099913800.037
synaptic transmissionGO:00072682350.037
response to cytokineGO:00340972150.037
regulation of wound healingGO:0061041140.037
rhythmic processGO:00485111560.036
vasculature developmentGO:0001944700.036
neuron projection developmentGO:00311752730.036
organophosphate metabolic processGO:00196373700.036
regulation of cyclase activityGO:0031279210.036
enzyme linked receptor protein signaling pathwayGO:00071671160.035
camp metabolic processGO:0046058630.035
cellular homeostasisGO:00197252520.035
cellular response to abiotic stimulusGO:0071214850.035
viral genome replicationGO:001907920.035
regenerationGO:00310991630.035
organelle organizationGO:00069962660.034
regulation of cell motilityGO:20001451310.034
protein processingGO:0016485680.033
positive regulation of biosynthetic processGO:00098913190.033
ion transmembrane transportGO:00342203650.033
very low density lipoprotein particle remodelingGO:003437210.033
regulation of apoptotic processGO:00429813350.033
cellular response to oxygen containing compoundGO:19017013860.033
Rat
response to ketoneGO:19016541820.032
Rat
positive regulation of phosphorus metabolic processGO:00105622620.032
cell motilityGO:00488702020.031
regulation of cell projection organizationGO:00313441750.031
regulation of cellular response to stressGO:0080135490.031
response to ethanolGO:00454711620.030
Rat
central nervous system developmentGO:00074173110.030
carbohydrate derivative catabolic processGO:19011361470.029
epithelium developmentGO:0060429960.029
endocytosisGO:0006897840.029
positive regulation of hydrolase activityGO:0051345860.028
intermediate filament based processGO:004510330.028
regulation of cellular component movementGO:00512701500.028
axis elongationGO:000340120.028
transmembrane transportGO:00550854120.028
positive regulation of ion transportGO:0043270940.027
positive regulation of neuron projection developmentGO:0010976990.027
kidney developmentGO:0001822670.027
tissue remodelingGO:0048771400.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
intermediate filament organizationGO:004510910.026
glycosyl compound metabolic processGO:19016571820.026
muscle cell differentiationGO:0042692520.025
integrin mediated signaling pathwayGO:000722970.025
negative regulation of immune system processGO:0002683390.025
cellular chemical homeostasisGO:00550822470.025
regulation of transmembrane transporter activityGO:0022898490.025
regulation of ion transmembrane transportGO:00347651210.025
regulation of protein metabolic processGO:00512462890.024
skeletal system developmentGO:0001501410.024
Rat
maternal process involved in female pregnancyGO:0060135380.024
regulation of synaptic transmissionGO:00508041410.024
cytolysisGO:001983540.024
regulation of cellular ketone metabolic processGO:0010565270.024
anterior posterior pattern specificationGO:000995210.024
response to cadmium ionGO:0046686350.024
small gtpase mediated signal transductionGO:0007264360.024
cartilage developmentGO:0051216220.024
response to toxic substanceGO:00096361330.023
positive regulation of cell developmentGO:00107201760.023
regulation of small gtpase mediated signal transductionGO:0051056480.023
cellular response to interleukin 1GO:0071347370.023
metal ion transportGO:00300012890.023
fatty acid derivative biosynthetic processGO:1901570180.023
neurological system processGO:00508772190.022
regulation of transmembrane transportGO:00347621220.022
cellular component morphogenesisGO:00329891550.022
cellular amino acid metabolic processGO:00065201070.022
regulation of neuron differentiationGO:00456642080.022
gliogenesisGO:0042063930.022
heart developmentGO:0007507720.022
positive regulation of cell deathGO:00109421840.022
regulation of proteolysisGO:0030162660.022
anatomical structure homeostasisGO:0060249290.022
positive regulation of apoptotic processGO:00430651540.021
regulation of signal transductionGO:00099663180.021
response to purine containing compoundGO:00140741260.021
skeletal muscle cell differentiationGO:003591420.021
nucleotide metabolic processGO:00091172790.021
cellular ketone metabolic processGO:0042180510.021
positive regulation of molecular functionGO:00440932300.021
blood vessel morphogenesisGO:0048514580.021
regulation of cell migrationGO:00303341280.021
cellular response to steroid hormone stimulusGO:0071383930.021
protein lipid complex remodelingGO:003436810.021
positive regulation of ion transmembrane transporter activityGO:0032414130.020
nucleobase containing small molecule metabolic processGO:00550863160.020
peptide cross linkingGO:001814910.020
amine metabolic processGO:0009308380.020
negative regulation of neurogenesisGO:0050768780.020
defense response to gram positive bacteriumGO:005083020.020
unsaturated fatty acid metabolic processGO:0033559390.020
protein heterooligomerizationGO:0051291890.020
response to organophosphorusGO:00466831020.020
head developmentGO:00603222470.020
negative regulation of atp catabolic processGO:190329020.020
regulation of molecular functionGO:00650093980.020
negative regulation of signalingGO:00230571570.020
calcium ion transportGO:00068161310.019
negative regulation of viral genome replicationGO:004507110.019
connective tissue developmentGO:0061448330.019
steroid biosynthetic processGO:0006694480.019
cellular response to molecule of bacterial originGO:0071219560.019
response to dexamethasoneGO:0071548490.019
regulation of nucleotide metabolic processGO:00061401170.019
cellular amine metabolic processGO:0044106380.019
regulation of catabolic processGO:00098941130.018
regulation of cellular catabolic processGO:00313291010.018
regulation of voltage gated calcium channel activityGO:190138560.018
monocarboxylic acid biosynthetic processGO:0072330480.018
chronic inflammatory responseGO:0002544160.018
purine nucleotide metabolic processGO:00061632290.018
gonad developmentGO:00084061040.017
negative regulation of protein processingGO:0010955470.017
negative regulation of apoptotic processGO:00430661810.017
regulation of calcium ion transmembrane transporter activityGO:1901019170.017
response to vitamin dGO:0033280340.016
Rat
small molecule biosynthetic processGO:00442831240.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.016
positive regulation of signal transductionGO:00099671750.016
positive regulation of ion transmembrane transportGO:0034767240.016
purine nucleotide catabolic processGO:00061951360.016
epithelial cell differentiationGO:0030855710.016
phosphatidylethanolamine metabolic processGO:004633710.016
regulation of protein modification processGO:00313991940.016
cellular response to metal ionGO:0071248550.016
cellular response to hypoxiaGO:0071456510.016
cellular response to biotic stimulusGO:0071216590.016
stress activated mapk cascadeGO:0051403350.016
transcription dna templatedGO:00063513770.016
response to interferon gammaGO:0034341200.015
defense response to gram negative bacteriumGO:005082930.015
platelet aggregationGO:007052740.015
response to starvationGO:0042594590.015
skeletal muscle organ developmentGO:0060538330.015
single organism catabolic processGO:00447122830.015
gland developmentGO:00487321550.015
regulation of cell morphogenesis involved in differentiationGO:0010769720.015
single organism organelle organizationGO:19025891800.015
regulation of camp biosynthetic processGO:0030817380.015
ribose phosphate metabolic processGO:00196932350.015
cellular response to hexose stimulusGO:0071331650.015
negative regulation of locomotionGO:0040013410.015
regulation of cellular amino acid metabolic processGO:000652120.015
circadian rhythmGO:0007623880.015
organic acid biosynthetic processGO:0016053830.015
regulation of purine nucleotide metabolic processGO:19005421150.015
protein maturationGO:0051604680.015
regulation of calcium ion transportGO:0051924770.015
respiratory system developmentGO:0060541450.014
regulation of cyclic nucleotide metabolic processGO:0030799510.014
negative regulation of programmed cell deathGO:00430691830.014
regulation of transcription dna templatedGO:00063553740.014
negative regulation of response to external stimulusGO:0032102370.014
response to mechanical stimulusGO:00096121340.014
secretionGO:00469033070.014
erythrocyte aggregationGO:003411710.014
positive regulation of camp metabolic processGO:0030816310.014
nucleic acid templated transcriptionGO:00976593790.014
camp biosynthetic processGO:0006171470.014
cellular response to reactive oxygen speciesGO:0034614550.014
positive regulation of intracellular signal transductionGO:19025331380.013
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.013
regulation of ras protein signal transductionGO:0046578450.013
positive regulation of transporter activityGO:0032411140.013
skeletal muscle tissue developmentGO:0007519310.013
glial cell developmentGO:0021782190.013
response to fatty acidGO:0070542650.013
regulation of peptidase activityGO:0052547550.013
negative regulation of cell developmentGO:0010721820.013
response to methylmercuryGO:0051597160.013
positive regulation of fibroblast proliferationGO:0048146150.013
positive regulation of cell projection organizationGO:00313461110.013
regulation of cellular protein metabolic processGO:00322682670.013
cellular response to vascular endothelial growth factor stimulusGO:003592460.013
fatty acid metabolic processGO:0006631990.013
positive regulation of cardiac muscle contractionGO:006045240.013
gamete generationGO:00072761240.013
regulation of heart morphogenesisGO:200082620.012
cellular protein localizationGO:00346131220.012
regulation of cellular amine metabolic processGO:003323880.012
carbohydrate homeostasisGO:0033500750.012
regulation of axonogenesisGO:0050770370.012
cellular response to oxygen levelsGO:0071453600.012
cellular metal ion homeostasisGO:00068751720.012
regulation of endopeptidase activityGO:0052548510.012
regulation of phosphorylationGO:00423252480.012
negative regulation of neuron projection developmentGO:0010977460.012
regulation of hydrolase activityGO:00513361430.012
autophagic cell deathGO:004810240.012
cation transportGO:00068123820.012
intermediate filament cytoskeleton organizationGO:004510430.012
cell cell signalingGO:00072673350.012
positive regulation of erk1 and erk2 cascadeGO:0070374290.012
purine containing compound metabolic processGO:00725212530.012
brain developmentGO:00074202470.012
immune system processGO:00023762040.012
glial cell migrationGO:0008347110.012
inflammatory responseGO:00069541500.012
muscle organ developmentGO:0007517500.012
purine containing compound catabolic processGO:00725231380.012
carbohydrate derivative biosynthetic processGO:19011371240.012
single organismal cell cell adhesionGO:0016337420.011
rho protein signal transductionGO:0007266110.011
purine nucleoside metabolic processGO:00422781690.011
neuronal action potentialGO:0019228350.011
negative regulation of transcription dna templatedGO:00458921160.011
regulation of cation channel activityGO:2001257230.011
negative regulation of endopeptidase activityGO:0010951360.011
negative regulation of secretionGO:0051048820.011
protein transportGO:00150311320.011
regulation of ion transmembrane transporter activityGO:0032412480.011
nucleoside triphosphate metabolic processGO:00091411440.011
regulation of growthGO:00400081050.011
proteoglycan metabolic processGO:000602930.011
cellular response to glucose stimulusGO:0071333650.011
cellular response to inorganic substanceGO:0071241650.011
organic substance catabolic processGO:19015753160.011
triglyceride homeostasisGO:007032820.011
sulfur compound biosynthetic processGO:0044272190.011
cellular macromolecule localizationGO:00707271220.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
negative regulation of peptidase activityGO:0010466380.011
positive regulation of cell communicationGO:00106472710.011
cellular response to corticosteroid stimulusGO:0071384690.011
neuron projection morphogenesisGO:00488121220.011
protein phosphorylationGO:00064683450.010
g protein coupled receptor signaling pathwayGO:00071862420.010
regulation of response to external stimulusGO:00321011060.010
organonitrogen compound biosynthetic processGO:19015661670.010
cellular response to platelet derived growth factor stimulusGO:003612070.010
purine ribonucleotide metabolic processGO:00091502270.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
response to temperature stimulusGO:0009266940.010
ribonucleotide metabolic processGO:00092592310.010
cardiac muscle tissue developmentGO:0048738260.010
inorganic cation transmembrane transportGO:00986622020.010
response to axon injuryGO:0048678590.010
action potentialGO:0001508540.010
regulation of cytokinesisGO:003246530.010
membrane lipid catabolic processGO:004646610.010

Mgp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
myopathyDOID:42300.017
intrinsic cardiomyopathyDOID:006003600.017
dilated cardiomyopathyDOID:1293000.017
disease of anatomical entityDOID:700.017
muscular diseaseDOID:008000000.017
cardiovascular system diseaseDOID:128700.017
muscle tissue diseaseDOID:6600.017
musculoskeletal system diseaseDOID:1700.017
cardiomyopathyDOID:005070000.017
heart diseaseDOID:11400.017
nervous system diseaseDOID:86300.016
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012