IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Fam148b

family with sequence similarity 148, member B

(Aliases: Nlf2)

Entrez: 501015
RGD: 1591932
UniProtKB: D3ZDJ2

Process Predictions
Disease Predictions

Fam148b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
response to nutrient	GO:0007584	248	0.245
metal ion homeostasis	GO:0055065	186	0.241
response to nutrient levels	GO:0031667	370	0.234
response to extracellular stimulus	GO:0009991	380	0.203
transmembrane transport	GO:0055085	412	0.162
response to carbohydrate	GO:0009743	183	0.140
cation transmembrane transport	GO:0098655	263	0.124
negative regulation of metabolic process	GO:0009892	331	0.117
inorganic cation transmembrane transport	GO:0098662	202	0.114
response to corticosteroid	GO:0031960	235	0.110
regulation of hormone secretion	GO:0046883	106	0.097
cellular response to endogenous stimulus	GO:0071495	377	0.094
cellular modified amino acid metabolic process	GO:0006575	61	0.093
divalent inorganic cation homeostasis	GO:0072507	165	0.088
cellular ion homeostasis	GO:0006873	184	0.087
calcium ion import	GO:0070509	22	0.083
calcium ion homeostasis	GO:0055074	162	0.082
response to oxygen levels	GO:0070482	265	0.080
homeostatic process	GO:0042592	331	0.079
cellular amino acid metabolic process	GO:0006520	107	0.078
cell cell signaling	GO:0007267	335	0.078
nitrogen compound transport	GO:0071705	229	0.074
inorganic ion transmembrane transport	GO:0098660	229	0.073
response to glucocorticoid	GO:0051384	223	0.073
nucleobase containing small molecule metabolic process	GO:0055086	316	0.073
organophosphate biosynthetic process	GO:0090407	143	0.073
negative regulation of cellular metabolic process	GO:0031324	281	0.070
positive regulation of transport	GO:0051050	245	0.067
cation homeostasis	GO:0055080	195	0.064
blood vessel development	GO:0001568	69	0.064
anatomical structure morphogenesis	GO:0009653	298	0.062
chemical homeostasis	GO:0048878	292	0.062
cellular calcium ion homeostasis	GO:0006874	160	0.061
positive regulation of developmental process	GO:0051094	283	0.058
cation transport	GO:0006812	382	0.056
signal release	GO:0023061	145	0.053
positive regulation of rna biosynthetic process	GO:1902680	197	0.049
response to bacterium	GO:0009617	200	0.048
rhythmic process	GO:0048511	156	0.048
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.048
response to lipopolysaccharide	GO:0032496	191	0.047
regulation of hormone levels	GO:0010817	187	0.047
cellular homeostasis	GO:0019725	252	0.047
regulation of peptide secretion	GO:0002791	82	0.047
growth	GO:0040007	165	0.046
peptide hormone secretion	GO:0030072	84	0.046
carbohydrate derivative metabolic process	GO:1901135	346	0.045
positive regulation of cell differentiation	GO:0045597	217	0.045
negative regulation of transport	GO:0051051	136	0.045
calcium ion transmembrane transport	GO:0070588	70	0.045
peptide secretion	GO:0002790	86	0.043
negative regulation of macromolecule metabolic process	GO:0010605	260	0.042
nucleotide metabolic process	GO:0009117	279	0.042
regulation of purine nucleotide metabolic process	GO:1900542	115	0.042
response to hypoxia	GO:0001666	231	0.041
hormone transport	GO:0009914	121	0.041
peptide transport	GO:0015833	97	0.040
developmental growth	GO:0048589	100	0.040
positive regulation of hormone secretion	GO:0046887	65	0.040
response to decreased oxygen levels	GO:0036293	237	0.039
amine metabolic process	GO:0009308	38	0.038
insulin like growth factor receptor signaling pathway	GO:0048009	3	0.038
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.038
aging	GO:0007568	241	0.038
response to other organism	GO:0051707	220	0.038
macromolecular complex assembly	GO:0065003	273	0.037
cellular response to nitrogen compound	GO:1901699	210	0.037
cellular cation homeostasis	GO:0030003	180	0.036
locomotion	GO:0040011	237	0.035
feeding behavior	GO:0007631	53	0.035
organophosphate metabolic process	GO:0019637	370	0.035
multicellular organism growth	GO:0035264	1	0.035
positive regulation of gene expression	GO:0010628	244	0.034
oxoacid metabolic process	GO:0043436	290	0.034
cytosolic calcium ion homeostasis	GO:0051480	140	0.033
ion transmembrane transport	GO:0034220	365	0.032
positive regulation of biosynthetic process	GO:0009891	319	0.031
positive regulation of transcription dna templated	GO:0045893	197	0.031
positive regulation of cellular component organization	GO:0051130	200	0.031
divalent metal ion transport	GO:0070838	132	0.031
purine nucleotide metabolic process	GO:0006163	229	0.031
regulation of multicellular organismal development	GO:2000026	376	0.031
regulation of cellular component organization	GO:0051128	368	0.031
response to axon injury	GO:0048678	59	0.031
maintenance of location	GO:0051235	17	0.031
calcium ion transport	GO:0006816	131	0.031
regulation of neuron projection development	GO:0010975	161	0.030
tissue development	GO:0009888	252	0.030
positive regulation of nucleotide metabolic process	GO:0045981	91	0.029
negative regulation of programmed cell death	GO:0043069	183	0.029
regulation of molecular function	GO:0065009	398	0.029
ion homeostasis	GO:0050801	212	0.029
regulation of phosphate metabolic process	GO:0019220	349	0.028
carbohydrate derivative biosynthetic process	GO:1901137	124	0.028
cellular response to hormone stimulus	GO:0032870	247	0.027
response to wounding	GO:0009611	254	0.027
response to vitamin	GO:0033273	131	0.027
nucleic acid templated transcription	GO:0097659	379	0.027
sensory perception of pain	GO:0019233	73	0.027
response to growth factor	GO:0070848	189	0.027
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.026
endocrine hormone secretion	GO:0060986	21	0.026
regulation of cellular amino acid metabolic process	GO:0006521	2	0.026
regulation of cell proliferation	GO:0042127	359	0.026
regulation of secretion by cell	GO:1903530	208	0.025
protein oligomerization	GO:0051259	191	0.025
leukocyte chemotaxis	GO:0030595	22	0.025
response to biotic stimulus	GO:0009607	226	0.025
protein complex biogenesis	GO:0070271	263	0.025
response to prostaglandin f	GO:0034696	4	0.025
regulation of nucleotide metabolic process	GO:0006140	117	0.025
positive regulation of cellular amine metabolic process	GO:0033240	3	0.025
proteolysis	GO:0006508	175	0.025
cyclic purine nucleotide metabolic process	GO:0052652	62	0.025
metal ion transport	GO:0030001	289	0.025
circulatory system development	GO:0072359	134	0.025
cellular amine metabolic process	GO:0044106	38	0.024
cellular component movement	GO:0006928	248	0.024
regulation of transmembrane transport	GO:0034762	122	0.024
response to electrical stimulus	GO:0051602	56	0.024
positive regulation of secretion	GO:0051047	140	0.024
cellular response to external stimulus	GO:0071496	118	0.024
carbohydrate metabolic process	GO:0005975	130	0.024
negative regulation of multicellular organismal process	GO:0051241	203	0.024
negative regulation of gene expression	GO:0010629	199	0.024
cell projection organization	GO:0030030	302	0.024
negative regulation of apoptotic process	GO:0043066	181	0.024
cellular metal ion homeostasis	GO:0006875	172	0.024
regulation of programmed cell death	GO:0043067	341	0.024
regulation of tube size	GO:0035150	89	0.023
somatostatin receptor signaling pathway	GO:0038169	4	0.023
circulatory system process	GO:0003013	183	0.023
regulation of carbohydrate metabolic process	GO:0006109	41	0.023
cellular response to corticosteroid stimulus	GO:0071384	69	0.023
protein complex assembly	GO:0006461	263	0.023
regulation of nucleic acid templated transcription	GO:1903506	380	0.022
response to molecule of bacterial origin	GO:0002237	194	0.022
cellular glucan metabolic process	GO:0006073	23	0.022
response to purine containing compound	GO:0014074	126	0.022
regulation of growth	GO:0040008	105	0.022
regulation of system process	GO:0044057	208	0.022
nucleoside phosphate metabolic process	GO:0006753	283	0.022
negative regulation of cell death	GO:0060548	229	0.022
lipid biosynthetic process	GO:0008610	128	0.022
response to external biotic stimulus	GO:0043207	221	0.022
positive regulation of response to stimulus	GO:0048584	285	0.021
neuron death	GO:0070997	127	0.021
cellular response to organonitrogen compound	GO:0071417	197	0.021
ribose phosphate metabolic process	GO:0019693	235	0.021
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.021
regulation of phosphorus metabolic process	GO:0051174	349	0.021
regulation of phagocytosis	GO:0050764	13	0.021
response to monosaccharide	GO:0034284	159	0.021
camp biosynthetic process	GO:0006171	47	0.021
cellular component assembly	GO:0022607	360	0.021
regulation of cyclic nucleotide biosynthetic process	GO:0030802	45	0.020
response to inorganic substance	GO:0010035	377	0.020
regulation of anatomical structure morphogenesis	GO:0022603	141	0.020
regulation of cellular localization	GO:0060341	263	0.020
positive regulation of ion transport	GO:0043270	94	0.020
regulation of cellular component movement	GO:0051270	150	0.020
chronic inflammatory response to non antigenic stimulus	GO:0002545	1	0.020
positive regulation of secretion by cell	GO:1903532	128	0.020
wound healing	GO:0042060	122	0.020
regulation of peptide transport	GO:0090087	87	0.020
positive regulation of peptide hormone secretion	GO:0090277	50	0.019
regulation of cell growth	GO:0001558	85	0.019
glucose homeostasis	GO:0042593	75	0.019
epithelial cell differentiation	GO:0030855	71	0.019
response to metal ion	GO:0010038	253	0.019
intracellular transport	GO:0046907	185	0.019
purine ribonucleotide metabolic process	GO:0009150	227	0.019
regulation of appetite	GO:0032098	8	0.019
positive regulation of cellular biosynthetic process	GO:0031328	295	0.019
muscle contraction	GO:0006936	88	0.019
development of primary female sexual characteristics	GO:0046545	56	0.019
immune system process	GO:0002376	204	0.018
response to fatty acid	GO:0070542	65	0.018
regulation of insulin secretion	GO:0050796	65	0.018
cellular response to steroid hormone stimulus	GO:0071383	93	0.018
hormone secretion	GO:0046879	115	0.018
cellular protein localization	GO:0034613	122	0.018
purine containing compound metabolic process	GO:0072521	253	0.018
rna metabolic process	GO:0016070	406	0.017
response to estrogen	GO:0043627	232	0.017
gamete generation	GO:0007276	124	0.017
positive regulation of phosphorylation	GO:0042327	177	0.017
second messenger mediated signaling	GO:0019932	51	0.017
synaptic transmission	GO:0007268	235	0.017
response to amino acid	GO:0043200	75	0.017
glycoprotein biosynthetic process	GO:0009101	19	0.017
glucan metabolic process	GO:0044042	23	0.017
response to cytokine	GO:0034097	215	0.017
regulation of cellular carbohydrate metabolic process	GO:0010675	39	0.017
positive regulation of neuron differentiation	GO:0045666	126	0.017
multicellular organism reproduction	GO:0032504	233	0.017
negative regulation of cell communication	GO:0010648	158	0.017
insulin secretion	GO:0030073	69	0.017
cellular chemical homeostasis	GO:0055082	247	0.017
regulation of cell projection organization	GO:0031344	175	0.017
carboxylic acid metabolic process	GO:0019752	289	0.016
amide transport	GO:0042886	105	0.016
negative regulation of secretion	GO:0051048	82	0.016
macromolecule localization	GO:0033036	252	0.016
neuron apoptotic process	GO:0051402	88	0.016
response to hexose	GO:0009746	144	0.016
organonitrogen compound biosynthetic process	GO:1901566	167	0.016
protein phosphorylation	GO:0006468	345	0.016
negative regulation of molecular function	GO:0044092	133	0.016
negative regulation of cellular protein metabolic process	GO:0032269	106	0.016
behavior	GO:0007610	205	0.016
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.016
programmed cell death	GO:0012501	392	0.016
regulation of skeletal muscle tissue regeneration	GO:0043416	2	0.016
response to zinc ion	GO:0010043	39	0.016
positive regulation of multicellular organismal process	GO:0051240	387	0.016
adenylate cyclase inhibiting opioid receptor signaling pathway	GO:0031635	2	0.016
protein kinase c activating g protein coupled receptor signaling pathway	GO:0007205	12	0.016
detection of temperature stimulus	GO:0016048	4	0.016
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.015
neurotransmitter transport	GO:0006836	42	0.015
regulation of rna biosynthetic process	GO:2001141	381	0.015
regulation of peptide hormone secretion	GO:0090276	80	0.015
cartilage condensation	GO:0001502	2	0.015
regulation of neuron death	GO:1901214	115	0.015
secretion by cell	GO:0032940	248	0.015
single organism behavior	GO:0044708	130	0.015
prostate gland growth	GO:0060736	1	0.015
regulation of sensory perception of pain	GO:0051930	29	0.015
ribonucleotide metabolic process	GO:0009259	231	0.015
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.015
cgmp biosynthetic process	GO:0006182	15	0.015
response to peptide hormone	GO:0043434	278	0.015
regulation of cell development	GO:0060284	263	0.015
regulation of cell morphogenesis	GO:0022604	77	0.015
regulation of neurotransmitter uptake	GO:0051580	1	0.015
negative regulation of phosphate metabolic process	GO:0045936	80	0.015
negative regulation of signal transduction	GO:0009968	83	0.015
generation of precursor metabolites and energy	GO:0006091	62	0.015
protein heterooligomerization	GO:0051291	89	0.014
glycogen metabolic process	GO:0005977	23	0.014
defense response	GO:0006952	194	0.014
multi organism reproductive process	GO:0044703	262	0.014
regulation of sequence specific dna binding transcription factor activity	GO:0051090	35	0.014
sequestering of metal ion	GO:0051238	9	0.014
sequestering of calcium ion	GO:0051208	8	0.014
transcription from rna polymerase ii promoter	GO:0006366	252	0.014
regeneration	GO:0031099	163	0.014
transcription dna templated	GO:0006351	377	0.014
regulation of dendrite development	GO:0050773	59	0.014
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.014
positive regulation of calcium ion transport	GO:0051928	36	0.014
rna biosynthetic process	GO:0032774	380	0.014
reactive oxygen species metabolic process	GO:0072593	37	0.014
cellular macromolecule localization	GO:0070727	122	0.014
regulation of nervous system development	GO:0051960	264	0.014
positive regulation of glomerular mesangial cell proliferation	GO:0072126	4	0.014
cell morphogenesis involved in differentiation	GO:0000904	119	0.014
molting cycle	GO:0042303	3	0.014
neurological system process	GO:0050877	219	0.014
response to mechanical stimulus	GO:0009612	134	0.014
positive regulation of purine nucleotide biosynthetic process	GO:1900373	36	0.014
organic acid metabolic process	GO:0006082	292	0.013
positive regulation of response to food	GO:0032097	3	0.013
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.013
regulation of apoptotic process	GO:0042981	335	0.013
purine containing compound biosynthetic process	GO:0072522	85	0.013
positive regulation of fat cell proliferation	GO:0070346	1	0.013
regulation of neuron apoptotic process	GO:0043523	83	0.013
ovulation cycle process	GO:0022602	50	0.013
positive regulation of phagocytosis	GO:0050766	9	0.013
regulation of metal ion transport	GO:0010959	118	0.013
ribose phosphate biosynthetic process	GO:0046390	87	0.013
negative regulation of neuron death	GO:1901215	69	0.013
cyclic nucleotide biosynthetic process	GO:0009190	63	0.013
cellular response to cytokine stimulus	GO:0071345	127	0.013
regulation of cell differentiation	GO:0045595	320	0.013
cell growth	GO:0016049	104	0.013
sensory perception	GO:0007600	101	0.013
response to ethanol	GO:0045471	162	0.013
apoptotic process	GO:0006915	381	0.013
retina morphogenesis in camera type eye	GO:0060042	1	0.013
positive regulation of catalytic activity	GO:0043085	184	0.013
regulation of ion transport	GO:0043269	245	0.013
positive regulation of molecular function	GO:0044093	230	0.013
molting cycle process	GO:0022404	2	0.012
positive regulation of protein modification process	GO:0031401	142	0.012
cytoplasmic transport	GO:0016482	115	0.012
regulation of secretion	GO:0051046	224	0.012
protein complex subunit organization	GO:0071822	302	0.012
macromolecular complex subunit organization	GO:0043933	339	0.012
response to light stimulus	GO:0009416	52	0.012
spermatogenesis	GO:0007283	99	0.012
regulation of transcription dna templated	GO:0006355	374	0.012
single organism intracellular transport	GO:1902582	166	0.012
cellular response to growth factor stimulus	GO:0071363	162	0.012
female sex differentiation	GO:0046660	59	0.012
regulation of calcium ion transport	GO:0051924	77	0.012
polysaccharide metabolic process	GO:0005976	25	0.012
male gamete generation	GO:0048232	99	0.012
cognition	GO:0050890	92	0.012
cellular carbohydrate metabolic process	GO:0044262	72	0.012
regulation of blood circulation	GO:1903522	110	0.012
positive regulation of cell proliferation	GO:0008284	249	0.011
regulation of response to wounding	GO:1903034	69	0.011
positive regulation of insulin secretion	GO:0032024	36	0.011
regulation of cyclase activity	GO:0031279	21	0.011
cell type specific apoptotic process	GO:0097285	134	0.011
eosinophil migration	GO:0072677	3	0.011
regulation of locomotion	GO:0040012	148	0.011
positive regulation of growth	GO:0045927	55	0.011
positive regulation of serotonin secretion	GO:0014064	1	0.011
hair cycle process	GO:0022405	2	0.011
cardiac muscle contraction	GO:0060048	27	0.011
negative regulation of chronic inflammatory response	GO:0002677	2	0.011
response to acid chemical	GO:0001101	222	0.011
intracellular signal transduction	GO:0035556	314	0.011
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.011
somatostatin signaling pathway	GO:0038170	4	0.011
reproductive process	GO:0022414	372	0.011
nucleoside phosphate biosynthetic process	GO:1901293	102	0.011
prostate gland morphogenesis	GO:0060512	2	0.011
energy reserve metabolic process	GO:0006112	25	0.011
taxis	GO:0042330	67	0.011
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	4	0.010
locomotor rhythm	GO:0045475	1	0.010
response to glucose	GO:0009749	136	0.010
regulation of sensory perception	GO:0051931	29	0.010
hexose transport	GO:0008645	29	0.010
divalent inorganic cation transport	GO:0072511	134	0.010
g protein coupled receptor signaling pathway	GO:0007186	242	0.010
epithelium development	GO:0060429	96	0.010

Fam148b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.029
respiratory system disease	DOID:1579	0.029
lower respiratory tract disease	DOID:0050161	0.029
long qt syndrome	DOID:2843	0.020
type 2 diabetes mellitus	DOID:9352	0.014
disease of metabolism	DOID:0014667	0.014
carbohydrate metabolism disease	DOID:0050013	0.014
glucose metabolism disease	DOID:4194	0.014
acquired metabolic disease	DOID:0060158	0.014
diabetes mellitus	DOID:9351	0.014
nervous system disease	DOID:863	0.013
disease of cellular proliferation	DOID:14566	0.011

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