Rattus norvegicus

0 known processes

Otp

orthopedia homeobox

Otp biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of multicellular organismal processGO:00512403870.355
regulation of phosphate metabolic processGO:00192203490.161
programmed cell deathGO:00125013920.150
homeostatic processGO:00425923310.139
positive regulation of cell proliferationGO:00082842490.136
inflammatory responseGO:00069541500.130
response to biotic stimulusGO:00096072260.124
regulation of cell differentiationGO:00455953200.123
positive regulation of cell differentiationGO:00455972170.115
positive regulation of nitrogen compound metabolic processGO:00511733340.112
positive regulation of kinase activityGO:0033674770.110
negative regulation of nitrogen compound metabolic processGO:00511721610.107
protein phosphorylationGO:00064683450.095
cation transportGO:00068123820.088
positive regulation of neurogenesisGO:00507691650.085
positive regulation of nervous system developmentGO:00519621780.084
positive regulation of nucleobase containing compound metabolic processGO:00459353190.077
regulation of neuron differentiationGO:00456642080.077
reproductive processGO:00224143720.075
secretion by cellGO:00329402480.074
positive regulation of cell developmentGO:00107201760.072
negative regulation of nucleobase containing compound metabolic processGO:00459341530.071
organic acid metabolic processGO:00060822920.069
regulation of rna biosynthetic processGO:20011413810.066
response to peptide hormoneGO:00434342780.065
negative regulation of macromolecule biosynthetic processGO:00105581480.063
regulation of neurogenesisGO:00507672470.063
cellular amine metabolic processGO:0044106380.062
ion transmembrane transportGO:00342203650.062
regulation of nucleic acid templated transcriptionGO:19035063800.061
peptidyl tyrosine phosphorylationGO:0018108720.061
intracellular signal transductionGO:00355563140.060
peptidyl amino acid modificationGO:00181931260.060
single organism reproductive processGO:00447022970.058
regulation of secretion by cellGO:19035302080.057
regulation of rna metabolic processGO:00512523910.056
positive regulation of phosphate metabolic processGO:00459372620.055
sex differentiationGO:00075481130.051
macromolecule localizationGO:00330362520.050
regulation of hormone secretionGO:00468831060.050
defense responseGO:00069521940.049
brain renin angiotensin systemGO:000203530.049
negative regulation of cellular biosynthetic processGO:00313271610.048
amine metabolic processGO:0009308380.048
regulation of phosphorylationGO:00423252480.048
positive regulation of cell communicationGO:00106472710.048
regulation of cellular component organizationGO:00511283680.047
response to peptideGO:19016522920.047
cellular response to oxygen containing compoundGO:19017013860.046
cell cell signalingGO:00072673350.046
regulation of cell developmentGO:00602842630.046
inorganic cation transmembrane transportGO:00986622020.046
metal ion transportGO:00300012890.046
agingGO:00075682410.046
multicellular organism reproductionGO:00325042330.045
secretionGO:00469033070.045
regulation of cellular localizationGO:00603412630.045
positive regulation of rna metabolic processGO:00512542030.045
transcription dna templatedGO:00063513770.045
regulation of cell proliferationGO:00421273590.045
cellular response to stressGO:00335542690.044
regulation of cell projection organizationGO:00313441750.044
multicellular organismal homeostasisGO:0048871490.044
reproductive system developmentGO:00614581280.043
nucleotide metabolic processGO:00091172790.043
regulation of phosphorus metabolic processGO:00511743490.043
positive regulation of signalingGO:00230562700.042
tissue developmentGO:00098882520.042
cell projection organizationGO:00300303020.041
positive regulation of transcription dna templatedGO:00458931970.041
hormone secretionGO:00468791150.040
response to cytokineGO:00340972150.040
negative regulation of cellular metabolic processGO:00313242810.039
response to nutrient levelsGO:00316673700.039
positive regulation of phosphorylationGO:00423271770.039
response to woundingGO:00096112540.038
positive regulation of biosynthetic processGO:00098913190.038
positive regulation of macromolecule biosynthetic processGO:00105572470.038
neuron differentiationGO:00301823680.038
response to external biotic stimulusGO:00432072210.037
regulation of growthGO:00400081050.037
divalent metal ion transportGO:00708381320.037
vitamin d metabolic processGO:004235940.036
protein transportGO:00150311320.036
establishment of protein localizationGO:00451841410.036
nucleic acid templated transcriptionGO:00976593790.036
regulation of protein modification processGO:00313991940.036
regulation of cellular amine metabolic processGO:003323880.035
cellular ketone metabolic processGO:0042180510.035
positive regulation of rna biosynthetic processGO:19026801970.035
positive regulation of developmental processGO:00510942830.035
positive regulation of cellular biosynthetic processGO:00313282950.034
regulation of cellular amino acid metabolic processGO:000652120.034
positive regulation of phosphorus metabolic processGO:00105622620.034
response to oxygen levelsGO:00704822650.034
response to alkaloidGO:00432791320.034
negative regulation of metabolic processGO:00098923310.034
regulation of transcription dna templatedGO:00063553740.033
negative regulation of transcription dna templatedGO:00458921160.033
lymphocyte activationGO:0046649430.032
positive regulation of immune system processGO:0002684900.032
single organism intracellular transportGO:19025821660.032
response to estrogenGO:00436272320.032
response to radiationGO:00093141370.032
regulation of apoptotic processGO:00429813350.031
negative regulation of developmental processGO:00510931250.031
neuron projection developmentGO:00311752730.031
positive regulation of secretionGO:00510471400.031
multicellular organismal reproductive processGO:00486092330.031
cellular homeostasisGO:00197252520.030
nucleobase containing small molecule metabolic processGO:00550863160.030
cellular response to lipidGO:00713962010.030
response to corticosteroidGO:00319602350.030
regulation of catalytic activityGO:00507903040.030
gamete generationGO:00072761240.030
mapk cascadeGO:00001651400.030
carbohydrate derivative metabolic processGO:19011353460.029
regulation of neuron projection developmentGO:00109751610.029
response to extracellular stimulusGO:00099913800.029
protein maturationGO:0051604680.028
regulation of leukocyte activationGO:0002694450.028
positive regulation of neuron differentiationGO:00456661260.028
immune responseGO:00069551040.028
cerebral cortex tangential migrationGO:002180010.028
regulation of protein metabolic processGO:00512462890.028
regulation of transmembrane transportGO:00347621220.027
regulation of molecular functionGO:00650093980.027
regulation of homeostatic processGO:00328441010.027
reproductionGO:00000032450.027
development of primary sexual characteristicsGO:00451371070.027
response to molecule of bacterial originGO:00022371940.027
regulation of cellular protein metabolic processGO:00322682670.026
growthGO:00400071650.026
positive regulation of transportGO:00510502450.026
neuron developmentGO:00486662860.026
response to oxidative stressGO:00069791860.026
multi organism reproductive processGO:00447032620.026
negative regulation of rna biosynthetic processGO:19026791180.026
positive regulation of nucleic acid templated transcriptionGO:19035081970.025
sodium ion transmembrane transportGO:0035725670.025
positive regulation of jak stat cascadeGO:0046427190.025
jak stat cascadeGO:0007259260.025
regulation of transcription from rna polymerase ii promoterGO:00063572340.025
regulation of signal transductionGO:00099663180.025
positive regulation of cellular protein metabolic processGO:00322701670.025
single organism biosynthetic processGO:00447113420.025
negative regulation of multicellular organismal processGO:00512412030.025
negative regulation of apoptotic processGO:00430661810.025
regenerationGO:00310991630.025
regulation of immune system processGO:00026821230.025
regulation of kinase activityGO:00435491170.025
lymphoid progenitor cell differentiationGO:000232020.025
single organism organelle organizationGO:19025891800.025
negative regulation of gene expressionGO:00106291990.025
protein localizationGO:00081041910.024
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.024
cellular response to biotic stimulusGO:0071216590.024
positive regulation of cytokine productionGO:0001819420.024
negative regulation of rna metabolic processGO:00512531230.024
anatomical structure homeostasisGO:0060249290.024
regulation of hormone levelsGO:00108171870.024
carboxylic acid metabolic processGO:00197522890.024
cellular amino acid metabolic processGO:00065201070.023
positive regulation of protein modification processGO:00314011420.023
ion homeostasisGO:00508012120.023
chemical homeostasisGO:00488782920.023
cell activationGO:0001775970.023
negative regulation of macromolecule metabolic processGO:00106052600.023
ribose phosphate biosynthetic processGO:0046390870.023
intramembranous ossificationGO:000195710.023
muscle system processGO:00030121150.023
positive regulation of response to stimulusGO:00485842850.023
female pregnancyGO:00075651220.023
regulation of nervous system developmentGO:00519602640.023
cell type specific apoptotic processGO:00972851340.023
response to hexoseGO:00097461440.022
peptide biosynthetic processGO:004304330.022
action potentialGO:0001508540.022
cellular response to growth factor stimulusGO:00713631620.022
regulation of locomotionGO:00400121480.022
transcription from rna polymerase ii promoterGO:00063662520.022
regulation of system processGO:00440572080.022
response to reactive oxygen speciesGO:00003021200.022
positive regulation of protein kinase activityGO:0045860730.022
cyclic nucleotide biosynthetic processGO:0009190630.022
rna metabolic processGO:00160704060.022
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.022
cellular response to peptide hormone stimulusGO:00713751200.022
positive regulation of catalytic activityGO:00430851840.022
regulation of programmed cell deathGO:00430673410.021
response to metal ionGO:00100382530.021
positive regulation of molecular functionGO:00440932300.021
positive regulation of signal transductionGO:00099671750.021
positive regulation of cellular amine metabolic processGO:003324030.021
inorganic ion transmembrane transportGO:00986602290.021
negative regulation of transportGO:00510511360.021
leukocyte activationGO:0045321760.021
male gonad developmentGO:0008584590.021
monovalent inorganic cation transportGO:00156721720.021
oxoacid metabolic processGO:00434362900.021
positive regulation of cellular amino acid metabolic processGO:004576410.020
proteolysisGO:00065081750.020
cellular ion homeostasisGO:00068731840.020
regulation of cellular ketone metabolic processGO:0010565270.020
protein complex subunit organizationGO:00718223020.020
g protein coupled receptor signaling pathwayGO:00071862420.020
positive regulation of protein metabolic processGO:00512471780.020
cellular component movementGO:00069282480.020
protein autophosphorylationGO:0046777660.020
motor neuron axon guidanceGO:000804510.019
endocrine processGO:0050886320.019
muscle contractionGO:0006936880.019
developmental process involved in reproductionGO:00030061590.019
positive regulation of purine nucleotide metabolic processGO:1900544910.019
ossificationGO:0001503700.019
cellular component morphogenesisGO:00329891550.019
apoptotic processGO:00069153810.019
cytokine productionGO:0001816610.019
cellular chemical homeostasisGO:00550822470.019
positive regulation of cytosolic calcium ion concentrationGO:00072041220.019
positive regulation of humoral immune responseGO:000292220.019
rna biosynthetic processGO:00327743800.019
sexual reproductionGO:00199531480.019
organophosphate metabolic processGO:00196373700.019
regulation of mapk cascadeGO:00434081160.019
gliogenesisGO:0042063930.019
neurological system processGO:00508772190.018
regulation of establishment of protein localizationGO:0070201690.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.018
intracellular transportGO:00469071850.018
regulation of protein phosphorylationGO:00019321830.018
negative regulation of biosynthetic processGO:00098901680.018
organic acid transportGO:00158491160.018
brain developmentGO:00074202470.018
spermatogenesisGO:0007283990.018
anatomical structure morphogenesisGO:00096532980.017
sensory perceptionGO:00076001010.017
positive regulation of protein phosphorylationGO:00019341350.017
cellular catabolic processGO:00442482950.017
ribose phosphate metabolic processGO:00196932350.017
regulation of ion transmembrane transportGO:00347651210.017
single organism catabolic processGO:00447122830.017
cellular calcium ion homeostasisGO:00068741600.017
regulation of hydrolase activityGO:00513361430.017
reproductive structure developmentGO:00486081280.017
response to temperature stimulusGO:0009266940.017
enzyme linked receptor protein signaling pathwayGO:00071671160.017
regulation of ion transportGO:00432692450.017
regulation of multicellular organismal developmentGO:20000263760.017
organonitrogen compound biosynthetic processGO:19015661670.017
positive regulation of intracellular signal transductionGO:19025331380.017
negative regulation of cell differentiationGO:0045596990.017
cellular response to interleukin 1GO:0071347370.017
carbohydrate derivative biosynthetic processGO:19011371240.016
positive regulation of cellular component organizationGO:00511302000.016
positive regulation of secretion by cellGO:19035321280.016
response to retinoic acidGO:0032526630.016
regulation of secretionGO:00510462240.016
potassium ion transportGO:0006813970.016
single organism cellular localizationGO:19025801020.016
neuron deathGO:00709971270.016
response to lipopolysaccharideGO:00324961910.016
activation of cysteine type endopeptidase activityGO:009720240.015
protein complex biogenesisGO:00702712630.015
regulation of cytokine productionGO:0001817560.015
positive regulation of cell projection organizationGO:00313461110.015
organic hydroxy compound metabolic processGO:19016151150.015
cell growthGO:00160491040.015
positive regulation of apoptotic processGO:00430651540.015
positive regulation of programmed cell deathGO:00430681570.015
catabolic processGO:00090563510.015
lipid metabolic processGO:00066292830.015
synaptic transmissionGO:00072682350.015
regulation of protein transportGO:0051223680.015
ribonucleotide biosynthetic processGO:0009260850.015
positive regulation of transferase activityGO:0051347810.015
sodium ion transportGO:0006814820.015
regulation of response to stressGO:00801341260.015
head developmentGO:00603222470.015
regulation of peptide secretionGO:0002791820.015
positive regulation of cell deathGO:00109421840.015
inflammatory response to antigenic stimulusGO:0002437180.015
regulation of organelle organizationGO:0033043800.015
skeletal muscle contractionGO:0003009170.015
purine containing compound biosynthetic processGO:0072522850.015
organ regenerationGO:00311001010.015
regulation of metal ion transportGO:00109591180.015
negative regulation of ion transportGO:0043271510.014
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.014
positive regulation of gene expressionGO:00106282440.014
organic hydroxy compound biosynthetic processGO:1901617510.014
peptide secretionGO:0002790860.014
response to growth factorGO:00708481890.014
oxidation reduction processGO:00551143040.014
cytoskeleton organizationGO:00070101110.014
regulation of sodium ion transportGO:0002028210.014
establishment of anatomical structure orientationGO:004856010.014
cellular cation homeostasisGO:00300031800.014
macromolecular complex subunit organizationGO:00439333390.014
immune system processGO:00023762040.014
positive regulation of neuron projection developmentGO:0010976990.014
peptidyl tyrosine modificationGO:0018212720.014
male sex differentiationGO:0046661640.014
protein complex assemblyGO:00064612630.014
cellular response to tumor necrosis factorGO:0071356460.014
negative regulation of cell deathGO:00605482290.014
t cell activationGO:0042110290.014
interleukin 18 productionGO:003262110.014
cell morphogenesis involved in differentiationGO:00009041190.014
nucleotide biosynthetic processGO:0009165980.014
neuron apoptotic processGO:0051402880.014
blood circulationGO:00080151830.013
response to glucocorticoidGO:00513842230.013
female gonad developmentGO:0008585530.013
lipid transportGO:0006869610.013
purine containing compound metabolic processGO:00725212530.013
epithelium developmentGO:0060429960.013
purine containing compound catabolic processGO:00725231380.013
central nervous system developmentGO:00074173110.013
positive regulation of mapk cascadeGO:0043410920.013
nucleoside metabolic processGO:00091161790.013
negative regulation of nervous system developmentGO:0051961790.013
response to inorganic substanceGO:00100353770.013
tissue homeostasisGO:0001894280.013
regulation of cellular catabolic processGO:00313291010.013
response to nutrientGO:00075842480.013
purine ribonucleotide metabolic processGO:00091502270.013
embryonic appendage morphogenesisGO:003511340.013
positive regulation of cellular component movementGO:00512721020.013
response to other organismGO:00517072200.013
male gamete generationGO:0048232990.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.013
alcohol metabolic processGO:0006066770.012
purine ribonucleotide biosynthetic processGO:0009152810.012
protein processingGO:0016485680.012
response to bacteriumGO:00096172000.012
positive regulation of ion transportGO:0043270940.012
regulation of neuron deathGO:19012141150.012
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.012
response to decreased oxygen levelsGO:00362932370.012
hematopoietic progenitor cell differentiationGO:000224420.012
negative regulation of neurogenesisGO:0050768780.012
nitrogen compound transportGO:00717052290.012
alcohol biosynthetic processGO:0046165380.012
purine nucleoside metabolic processGO:00422781690.012
regulation of jak stat cascadeGO:0046425210.012
response to monosaccharideGO:00342841590.012
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.012
negative regulation of programmed cell deathGO:00430691830.012
response to molecule of fungal originGO:000223830.012
calcium ion homeostasisGO:00550741620.012
regulation of sodium ion transmembrane transporter activityGO:200064940.012
divalent inorganic cation homeostasisGO:00725071650.012
metanephric comma shaped body morphogenesisGO:007227820.012
response to interleukin 1GO:0070555550.012
axis specificationGO:000979840.012
immune system developmentGO:0002520410.012
cellular metal ion homeostasisGO:00068751720.012
divalent inorganic cation transportGO:00725111340.012
negative regulation of uterine smooth muscle contractionGO:007047320.012
positive regulation of cellular catabolic processGO:0031331710.012
response to tumor necrosis factorGO:0034612560.012
positive regulation of hydrolase activityGO:0051345860.012
negative regulation of cell developmentGO:0010721820.012
cytosolic calcium ion homeostasisGO:00514801400.012
regulation of alternative mrna splicing via spliceosomeGO:000038120.012
cyclic purine nucleotide metabolic processGO:0052652620.011
calcium ion transmembrane transportGO:0070588700.011
regulation of protein kinase activityGO:00458591050.011
insulin secretionGO:0030073690.011
positive regulation of homeostatic processGO:0032846490.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
cellular response to lipopolysaccharideGO:0071222550.011
sensory perception of painGO:0019233730.011
regulation of transferase activityGO:00513381230.011
regulation of behaviorGO:0050795610.011
regulation of cell cycleGO:0051726730.011
regulation of saliva secretionGO:004687730.011
regulation of protein localizationGO:0032880810.011
regulation of intracellular signal transductionGO:19025312180.011
regulation of interferon gamma productionGO:003264930.011
response to mechanical stimulusGO:00096121340.011
organic hydroxy compound transportGO:0015850770.011
peptide hormone secretionGO:0030072840.011
cellular macromolecule localizationGO:00707271220.011
phospholipid metabolic processGO:0006644610.011
amide transportGO:00428861050.011
purine nucleotide metabolic processGO:00061632290.011
keratinocyte migrationGO:005154620.011
signal releaseGO:00230611450.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
cellular response to organic cyclic compoundGO:00714072020.011
regulation of cell morphogenesisGO:0022604770.011
lymphocyte proliferationGO:0046651290.011
neuropeptide signaling pathwayGO:0007218290.011
quaternary ammonium group transportGO:001569760.011
negative regulation of transporter activityGO:0032410130.011
hair cycleGO:004263330.011
somatostatin receptor signaling pathwayGO:003816940.010
negative regulation of neuron projection developmentGO:0010977460.010
development of primary male sexual characteristicsGO:0046546590.010
fatty acid transportGO:0015908250.010
response to transition metal nanoparticleGO:19902671220.010
hormone transportGO:00099141210.010
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.010
salivary gland developmentGO:000743130.010
cardiovascular system developmentGO:00723581340.010
response to hypoxiaGO:00016662310.010
regulation of synaptic transmissionGO:00508041410.010
molting cycleGO:004230330.010
autophagic cell deathGO:004810240.010
positive regulation of interferon gamma productionGO:003272920.010
lipid localizationGO:0010876620.010

Otp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.039
bone diseaseDOID:008000100.039
musculoskeletal system diseaseDOID:1700.039
disease of anatomical entityDOID:700.039
cardiovascular system diseaseDOID:128700.038
nervous system diseaseDOID:86300.015
sensory system diseaseDOID:005015500.015
eye and adnexa diseaseDOID:149200.013
vascular diseaseDOID:17800.011
eye diseaseDOID:561400.011
bone development diseaseDOID:008000600.010