Rattus norvegicus

0 known processes

Capn6

calpain 6

Capn6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tissue developmentGO:00098882520.484
Rat
intracellular signal transductionGO:00355563140.289
cell motilityGO:00488702020.225
anatomical structure morphogenesisGO:00096532980.214
ossificationGO:0001503700.199
cellular response to endogenous stimulusGO:00714953770.188
secretionGO:00469033070.171
regulation of signal transductionGO:00099663180.152
response to inorganic substanceGO:00100353770.152
organ morphogenesisGO:0009887750.136
regulation of intracellular signal transductionGO:19025312180.132
regulation of phosphorus metabolic processGO:00511743490.121
macromolecular complex subunit organizationGO:00439333390.120
response to nutrient levelsGO:00316673700.110
regulation of apoptotic processGO:00429813350.109
response to extracellular stimulusGO:00099913800.107
transcription dna templatedGO:00063513770.106
positive regulation of cell proliferationGO:00082842490.104
cellular response to peptide hormone stimulusGO:00713751200.102
locomotionGO:00400112370.101
regulation of cell differentiationGO:00455953200.099
cellular response to oxygen containing compoundGO:19017013860.096
positive regulation of cell deathGO:00109421840.095
multi organism reproductive processGO:00447032620.091
positive regulation of cell communicationGO:00106472710.090
regulation of multicellular organismal developmentGO:20000263760.088
rna metabolic processGO:00160704060.088
cell migrationGO:00164771970.087
regulation of rna metabolic processGO:00512523910.087
neuron projection developmentGO:00311752730.086
cell projection organizationGO:00300303020.082
reproductive processGO:00224143720.082
Rat
regulation of phosphate metabolic processGO:00192203490.082
salivary gland morphogenesisGO:000743510.081
cellular component movementGO:00069282480.079
regulation of molecular functionGO:00650093980.079
transcription from rna polymerase ii promoterGO:00063662520.079
programmed cell deathGO:00125013920.078
positive regulation of developmental processGO:00510942830.076
positive regulation of phosphate metabolic processGO:00459372620.074
gastrulationGO:000736920.074
positive regulation of cell migrationGO:0030335960.073
regulation of phosphorylationGO:00423252480.071
response to oxygen levelsGO:00704822650.071
regulation of programmed cell deathGO:00430673410.071
growthGO:00400071650.071
regulation of nucleic acid templated transcriptionGO:19035063800.069
response to decreased oxygen levelsGO:00362932370.069
localization of cellGO:00516742020.069
response to biotic stimulusGO:00096072260.068
agingGO:00075682410.068
cellular response to peptideGO:19016531330.068
organelle organizationGO:00069962660.068
Mouse
skeletal system developmentGO:0001501410.067
neuron differentiationGO:00301823680.067
regulation of transcription dna templatedGO:00063553740.066
regulation of cell developmentGO:00602842630.066
positive regulation of transcription dna templatedGO:00458931970.065
positive regulation of phosphorus metabolic processGO:00105622620.065
tissue morphogenesisGO:0048729220.065
positive regulation of macromolecule biosynthetic processGO:00105572470.064
metal ion transportGO:00300012890.064
negative regulation of signal transductionGO:0009968830.063
negative regulation of signalingGO:00230571570.063
epithelium developmentGO:0060429960.063
Rat
muscle tissue developmentGO:0060537580.062
embryonic appendage morphogenesisGO:003511340.062
response to peptideGO:19016522920.062
rna biosynthetic processGO:00327743800.062
response to nutrientGO:00075842480.061
appendage morphogenesisGO:003510740.061
g protein coupled receptor signaling pathwayGO:00071862420.059
regulation of canonical wnt signaling pathwayGO:006082840.058
response to metal ionGO:00100382530.058
response to glucocorticoidGO:00513842230.057
nucleic acid templated transcriptionGO:00976593790.057
single organism organelle organizationGO:19025891800.055
Mouse
cellular component morphogenesisGO:00329891550.055
apoptotic processGO:00069153810.055
response to corticosteroidGO:00319602350.055
cellular amino acid metabolic processGO:00065201070.055
cytosolic calcium ion homeostasisGO:00514801400.054
embryonic skeletal system developmentGO:004870630.054
response to hypoxiaGO:00016662310.054
negative regulation of response to stimulusGO:00485851550.054
positive regulation of nitrogen compound metabolic processGO:00511733340.053
response to acid chemicalGO:00011012220.053
positive regulation of molecular functionGO:00440932300.053
positive regulation of signal transductionGO:00099671750.051
regulation of rna biosynthetic processGO:20011413810.051
positive regulation of biosynthetic processGO:00098913190.050
positive regulation of programmed cell deathGO:00430681570.049
cellular carbohydrate metabolic processGO:0044262720.049
central nervous system developmentGO:00074173110.049
regulation of catalytic activityGO:00507903040.049
positive regulation of cell motilityGO:2000147970.049
regulation of cellular localizationGO:00603412630.048
response to purine containing compoundGO:00140741260.047
negative regulation of metabolic processGO:00098923310.046
macromolecular complex assemblyGO:00650032730.046
cellular response to lipidGO:00713962010.046
response to external biotic stimulusGO:00432072210.046
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.045
regulation of cellular protein metabolic processGO:00322682670.045
regulation of cell proliferationGO:00421273590.045
regulation of anatomical structure morphogenesisGO:00226031410.044
positive regulation of response to stimulusGO:00485842850.044
cellular response to organic cyclic compoundGO:00714072020.044
chemotaxisGO:0006935660.044
cell part morphogenesisGO:00329901230.044
negative regulation of nitrogen compound metabolic processGO:00511721610.044
osteoblast differentiationGO:0001649260.043
response to vitaminGO:00332731310.042
cytoskeleton organizationGO:00070101110.042
Mouse
epithelial cell proliferationGO:0050673540.042
response to estradiolGO:00323551640.042
organophosphate metabolic processGO:00196373700.042
brain developmentGO:00074202470.041
cellular component biogenesisGO:00440853680.041
morphogenesis of an epitheliumGO:0002009200.041
positive regulation of secretionGO:00510471400.041
positive regulation of nucleic acid templated transcriptionGO:19035081970.041
negative regulation of cellular biosynthetic processGO:00313271610.041
regulation of protein metabolic processGO:00512462890.041
response to growth factorGO:00708481890.040
positive regulation of phosphorylationGO:00423271770.040
cellular response to organonitrogen compoundGO:00714171970.040
regulation of cellular component organizationGO:00511283680.040
Mouse
positive regulation of intracellular signal transductionGO:19025331380.040
regulation of secretionGO:00510462240.040
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.040
insulin like growth factor receptor signaling pathwayGO:004800930.039
heart morphogenesisGO:000300730.039
negative regulation of cell communicationGO:00106481580.039
actin filament based processGO:0030029860.039
learning or memoryGO:0007611900.039
response to peptide hormoneGO:00434342780.039
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.038
response to woundingGO:00096112540.038
cardiac chamber developmentGO:000320510.038
cation transportGO:00068123820.038
positive regulation of apoptotic processGO:00430651540.038
positive regulation of gene expressionGO:00106282440.038
neuron developmentGO:00486662860.037
negative regulation of macromolecule metabolic processGO:00106052600.037
response to heatGO:0009408600.037
response to lipopolysaccharideGO:00324961910.037
cellular component assemblyGO:00226073600.037
cellular ketone metabolic processGO:0042180510.037
regulation of neurogenesisGO:00507672470.036
negative regulation of osteoblast differentiationGO:004566820.036
cell morphogenesis involved in differentiationGO:00009041190.036
regulation of metal ion transportGO:00109591180.036
regulation of cell motilityGO:20001451310.036
molting cycle processGO:002240420.036
connective tissue developmentGO:0061448330.036
nucleotide metabolic processGO:00091172790.035
sexual reproductionGO:00199531480.035
odontogenesisGO:0042476320.035
organonitrogen compound catabolic processGO:19015651790.035
cell cell signalingGO:00072673350.035
transformation of host cell by virusGO:001908740.035
positive regulation of rna metabolic processGO:00512542030.034
non canonical wnt signaling pathwayGO:003556730.034
ion transmembrane transportGO:00342203650.034
reproductionGO:00000032450.034
Rat
catabolic processGO:00090563510.034
regulation of cell migrationGO:00303341280.034
regulation of mesenchymal cell proliferationGO:001046440.034
calcium ion transportGO:00068161310.033
tube developmentGO:0035295890.033
gland developmentGO:00487321550.033
regulation of nervous system developmentGO:00519602640.033
axon developmentGO:0061564960.033
single organism intracellular transportGO:19025821660.033
protein complex subunit organizationGO:00718223020.033
embryo developmentGO:0009790490.033
negative regulation of canonical wnt signaling pathwayGO:009009040.033
negative regulation of cellular metabolic processGO:00313242810.032
negative regulation of biosynthetic processGO:00098901680.032
cellular response to growth factor stimulusGO:00713631620.032
regulation of hormone levelsGO:00108171870.032
mesenchymal cell proliferationGO:001046340.031
positive regulation of cellular component organizationGO:00511302000.031
response to transition metal nanoparticleGO:19902671220.031
positive regulation of rna biosynthetic processGO:19026801970.031
single organism reproductive processGO:00447022970.031
Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.031
actin cytoskeleton organizationGO:0030036730.031
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.031
positive regulation of transportGO:00510502450.030
circulatory system processGO:00030131830.030
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.030
regulation of protein phosphorylationGO:00019321830.030
blood vessel developmentGO:0001568690.030
protein phosphorylationGO:00064683450.030
regulation of locomotionGO:00400121480.030
single organism carbohydrate metabolic processGO:00447231180.030
cellular lipid metabolic processGO:00442552080.030
limb morphogenesisGO:003510840.030
head developmentGO:00603222470.030
blood circulationGO:00080151830.030
positive regulation of signalingGO:00230562700.029
regulation of carbohydrate metabolic processGO:0006109410.029
regulation of system processGO:00440572080.029
defense responseGO:00069521940.029
synaptic transmissionGO:00072682350.029
carbohydrate metabolic processGO:00059751300.029
negative regulation of cell deathGO:00605482290.029
homeostatic processGO:00425923310.029
regulation of cellular component movementGO:00512701500.029
regulation of homeostatic processGO:00328441010.029
eye morphogenesisGO:004859240.029
regulation of anatomical structure sizeGO:00900661350.029
signal transduction by phosphorylationGO:00230141440.029
neural crest cell developmentGO:001403220.028
response to campGO:0051591910.028
neuron projection morphogenesisGO:00488121220.028
chemical homeostasisGO:00488782920.028
cell projection morphogenesisGO:00488581230.028
cardiovascular system developmentGO:00723581340.028
single organism catabolic processGO:00447122830.028
muscle structure developmentGO:0061061870.028
cellular response to stressGO:00335542690.028
nucleoside phosphate metabolic processGO:00067532830.028
negative regulation of cell developmentGO:0010721820.028
negative regulation of gene expressionGO:00106291990.027
regulation of cellular ketone metabolic processGO:0010565270.027
camp metabolic processGO:0046058630.027
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.027
cell morphogenesisGO:00009021420.027
ribonucleotide metabolic processGO:00092592310.027
regulation of ion transportGO:00432692450.027
divalent metal ion transportGO:00708381320.027
cell growthGO:00160491040.027
cellular response to nitrogen compoundGO:19016992100.026
neural crest cell differentiationGO:001403320.026
circulatory system developmentGO:00723591340.026
secretion by cellGO:00329402480.026
multicellular organismal reproductive processGO:00486092330.026
Rat
negative regulation of rna metabolic processGO:00512531230.026
positive regulation of cellular biosynthetic processGO:00313282950.026
positive regulation of cell developmentGO:00107201760.026
insulin receptor signaling pathwayGO:0008286240.026
anatomical structure formation involved in morphogenesisGO:0048646830.026
multicellular organism reproductionGO:00325042330.026
Rat
maintenance of locationGO:0051235170.026
sequestering of calcium ionGO:005120880.026
glucose metabolic processGO:0006006520.026
embryonic limb morphogenesisGO:003032640.026
negative regulation of multicellular organismal processGO:00512412030.026
lipid metabolic processGO:00066292830.026
regulation of cellular carbohydrate metabolic processGO:0010675390.026
cellular response to alcoholGO:0097306870.026
positive regulation of cellular protein metabolic processGO:00322701670.026
cell adhesionGO:00071551100.026
response to other organismGO:00517072200.026
response to bacteriumGO:00096172000.025
sequestering of metal ionGO:005123890.025
response to ethanolGO:00454711620.025
biological adhesionGO:00226101100.025
regulation of neuron deathGO:19012141150.025
response to molecule of bacterial originGO:00022371940.025
wnt signaling pathwayGO:0016055170.025
cellular calcium ion homeostasisGO:00068741600.025
amine metabolic processGO:0009308380.025
calcium ion homeostasisGO:00550741620.025
enzyme linked receptor protein signaling pathwayGO:00071671160.025
endoplasmic reticulum to cytosol transportGO:190351340.024
regulation of blood pressureGO:0008217830.024
skeletal muscle tissue developmentGO:0007519310.024
calcium ion transport into cytosolGO:0060402380.024
positive regulation of cell differentiationGO:00455972170.024
response to retinoic acidGO:0032526630.024
response to organophosphorusGO:00466831020.024
regulation of smooth muscle cell migrationGO:0014910360.024
vesicle mediated transportGO:00161921810.024
response to axon injuryGO:0048678590.024
divalent inorganic cation transportGO:00725111340.024
formation of primary germ layerGO:000170410.024
embryonic skeletal system morphogenesisGO:004870430.023
positive regulation of mesenchymal cell proliferationGO:000205340.023
gliogenesisGO:0042063930.023
regenerationGO:00310991630.023
positive regulation of nucleobase containing compound metabolic processGO:00459353190.023
glial cell differentiationGO:0010001650.023
response to alkaloidGO:00432791320.023
organic substance catabolic processGO:19015753160.023
cellular response to hormone stimulusGO:00328702470.023
skin morphogenesisGO:004358920.023
regulation of neural precursor cell proliferationGO:2000177160.023
sarcoplasmic reticulum calcium ion transportGO:007029680.023
salivary gland developmentGO:000743130.022
purine ribonucleotide metabolic processGO:00091502270.022
intracellular transportGO:00469071850.022
cell type specific apoptotic processGO:00972851340.022
regulation of cellular amino acid metabolic processGO:000652120.022
cellular amine metabolic processGO:0044106380.022
protein complex assemblyGO:00064612630.022
positive regulation of neurogenesisGO:00507691650.022
positive regulation of cytosolic calcium ion concentrationGO:00072041220.022
positive regulation of nervous system developmentGO:00519621780.022
cellular response to acid chemicalGO:0071229750.022
tube morphogenesisGO:0035239230.022
single organismal cell cell adhesionGO:0016337420.022
multi multicellular organism processGO:00447061380.022
cartilage development involved in endochondral bone morphogenesisGO:006035130.022
regulation of cytoskeleton organizationGO:0051493490.022
Mouse
nucleobase containing small molecule metabolic processGO:00550863160.021
positive regulation of cellular component movementGO:00512721020.021
cellular divalent inorganic cation homeostasisGO:00725031620.021
glucose homeostasisGO:0042593750.021
cytosolic calcium ion transportGO:0060401390.021
skeletal muscle organ developmentGO:0060538330.021
single organism biosynthetic processGO:00447113420.021
mapk cascadeGO:00001651400.021
regulation of protein transportGO:0051223680.021
regulation of cellular amine metabolic processGO:003323880.021
axonogenesisGO:0007409710.021
ribose phosphate metabolic processGO:00196932350.020
positive regulation of locomotionGO:00400171020.020
negative regulation of nervous system developmentGO:0051961790.020
ameboidal type cell migrationGO:0001667260.020
positive regulation of catalytic activityGO:00430851840.020
receptor mediated endocytosisGO:0006898420.020
wound healingGO:00420601220.020
negative regulation of apoptotic processGO:00430661810.020
positive regulation of multicellular organismal processGO:00512403870.020
behaviorGO:00076102050.020
nucleotide catabolic processGO:00091661390.020
protein complex biogenesisGO:00702712630.020
skeletal muscle cell differentiationGO:003591420.020
smooth muscle cell migrationGO:0014909360.020
muscle cell migrationGO:0014812360.020
regulation of body fluid levelsGO:0050878900.020
striated muscle tissue developmentGO:0014706580.020
organonitrogen compound biosynthetic processGO:19015661670.020
regulation of establishment of planar polarityGO:009017520.019
neurological system processGO:00508772190.019
positive regulation of cellular amine metabolic processGO:003324030.019
cellular homeostasisGO:00197252520.019
regulation of ossificationGO:0030278320.019
purine nucleotide metabolic processGO:00061632290.019
artery developmentGO:006084030.019
response to radiationGO:00093141370.019
establishment of protein localizationGO:00451841410.019
regulation of protein modification processGO:00313991940.019
peptidyl amino acid modificationGO:00181931260.019
prostate gland epithelium morphogenesisGO:006074020.019
digestive system developmentGO:0055123410.019
organic hydroxy compound metabolic processGO:19016151150.019
hair follicle developmentGO:000194220.019
regulation of calcium ion transportGO:0051924770.018
vascular process in circulatory systemGO:0003018960.018
protein oligomerizationGO:00512591910.018
monosaccharide metabolic processGO:0005996610.018
regulation of epithelial cell proliferationGO:0050678490.018
hair cycle processGO:002240520.018
cellular catabolic processGO:00442482950.018
regulation of stem cell differentiationGO:200073620.018
purine containing compound metabolic processGO:00725212530.018
carbohydrate derivative metabolic processGO:19011353460.018
hindlimb morphogenesisGO:003513720.018
heterocycle catabolic processGO:00467001670.018
small gtpase mediated signal transductionGO:0007264360.018
positive regulation of mapk cascadeGO:0043410920.018
hormone transportGO:00099141210.017
response to oxidative stressGO:00069791860.017
negative regulation of transportGO:00510511360.017
regulation of secretion by cellGO:19035302080.017
ion homeostasisGO:00508012120.017
negative regulation of cell proliferationGO:00082851190.016
response to hydrogen peroxideGO:0042542890.016
anterior posterior pattern specificationGO:000995210.016
tissue remodelingGO:0048771400.016
wnt signaling pathway planar cell polarity pathwayGO:006007120.016
response to hexoseGO:00097461440.016
neuronal action potentialGO:0019228350.016
neuron deathGO:00709971270.016
hexose metabolic processGO:0019318580.016
ras protein signal transductionGO:0007265290.016
protein transportGO:00150311320.016
response to vitamin dGO:0033280340.016
neuron apoptotic processGO:0051402880.016
ureteric bud developmentGO:0001657140.015
cytoplasmic transportGO:00164821150.015
palate developmentGO:006002120.015
forebrain developmentGO:0030900980.015
cation transmembrane transportGO:00986552630.015
cell morphogenesis involved in neuron differentiationGO:00486671060.015
negative regulation of neurogenesisGO:0050768780.015
response to insulinGO:00328681330.015
regulation of mapk cascadeGO:00434081160.015
response to indole 3 methanolGO:007168020.015
inorganic cation transmembrane transportGO:00986622020.015
aromatic compound catabolic processGO:00194391680.015
negative regulation of protein metabolic processGO:00512481140.015
cardiac ventricle developmentGO:000323110.015
embryonic pattern specificationGO:000988010.015
negative regulation of phosphate metabolic processGO:0045936800.015
cognitionGO:0050890920.015
olfactory behaviorGO:004204820.015
regulation of neuron projection developmentGO:00109751610.015
autonomic nervous system developmentGO:004848330.015
response to estrogenGO:00436272320.015
organic cyclic compound catabolic processGO:19013611750.015
renal system developmentGO:0072001670.015
nucleoside phosphate catabolic processGO:19012921400.015
regulation of smoothened signaling pathwayGO:000858920.015
purine nucleotide catabolic processGO:00061951360.015
response to carbohydrateGO:00097431830.014
carbohydrate biosynthetic processGO:0016051420.014
development of primary sexual characteristicsGO:00451371070.014
Rat
cellular response to steroid hormone stimulusGO:0071383930.014
regulation of neuron differentiationGO:00456642080.014
motor neuron axon guidanceGO:000804510.014
establishment of tissue polarityGO:000716420.014
hair cycleGO:004263330.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
peptidyl tyrosine modificationGO:0018212720.014
positive regulation of immune system processGO:0002684900.014
growth plate cartilage developmentGO:000341720.014
carbohydrate derivative catabolic processGO:19011361470.014
smooth muscle cell proliferationGO:0048659770.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
heart developmentGO:0007507720.014
axis specificationGO:000979840.014
positive regulation of secretion by cellGO:19035321280.014
release of sequestered calcium ion into cytosolGO:0051209250.014
small molecule catabolic processGO:0044282590.014
positive regulation of smoothened signaling pathwayGO:004588010.014
regulation of hydrolase activityGO:00513361430.014
action potentialGO:0001508540.014
regulation of ion homeostasisGO:2000021630.014
camera type eye morphogenesisGO:004859320.013
macromolecule localizationGO:00330362520.013
urogenital system developmentGO:0001655780.013
mesonephros developmentGO:0001823140.013
negative regulation of programmed cell deathGO:00430691830.013
establishment of planar polarityGO:000173610.013
negative regulation of developmental processGO:00510931250.013
positive regulation of transferase activityGO:0051347810.013
negative regulation of cellular protein metabolic processGO:00322691060.013
kidney developmentGO:0001822670.013
regulation of neuron apoptotic processGO:0043523830.013
nucleoside catabolic processGO:00091641260.013
positive regulation of protein metabolic processGO:00512471780.013
morphogenesis of a polarized epitheliumGO:000173810.013
mammary gland developmentGO:0030879380.013
nucleobase containing compound catabolic processGO:00346551520.013
ribonucleoside metabolic processGO:00091191740.013
proteolysisGO:00065081750.013
spermatogenesisGO:0007283990.013
muscle organ developmentGO:0007517500.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
blood vessel morphogenesisGO:0048514580.013
response to low density lipoprotein particleGO:005509840.013
hormone secretionGO:00468791150.013
divalent inorganic cation homeostasisGO:00725071650.013
purine ribonucleoside catabolic processGO:00461301240.013
regulation of synaptic transmissionGO:00508041410.012
gamete generationGO:00072761240.012
regulation of transferase activityGO:00513381230.012
cellular response to retinoic acidGO:0071300270.012
cellular response to abiotic stimulusGO:0071214850.012
negative regulation of secretionGO:0051048820.012
positive regulation of neuron differentiationGO:00456661260.012
neural crest cell migrationGO:000175510.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
negative regulation of wnt signaling pathwayGO:003017870.012
negative regulation of neuron differentiationGO:0045665620.012
regulation of tube sizeGO:0035150890.012
nitrogen compound transportGO:00717052290.012
regulation of immune system processGO:00026821230.012
taxisGO:0042330670.012
cellular response to oxidative stressGO:0034599760.012
regulation of cellular component biogenesisGO:0044087860.012
mesoderm developmentGO:000749820.012
positive regulation of protein phosphorylationGO:00019341350.012
muscle cell proliferationGO:0033002840.012
response to calcium ionGO:0051592590.012
purine ribonucleotide catabolic processGO:00091541360.012
developmental growthGO:00485891000.012
transmembrane transportGO:00550854120.012
male mating behaviorGO:006017930.012
regulation of cell projection organizationGO:00313441750.012

Capn6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.018
nervous system diseaseDOID:86300.018
urinary system diseaseDOID:1800.015
kidney diseaseDOID:55700.015
bone diseaseDOID:008000100.014
connective tissue diseaseDOID:6500.014
musculoskeletal system diseaseDOID:1700.014
bone development diseaseDOID:008000600.012
osteochondrodysplasiaDOID:225600.012