IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Cyp2b21

cytochrome P450, family 2, subfamily b, polypeptide 21

(Aliases: Cyp2b13)

RGD: 735174
Entrez: 292728
Ensembl: ENSRNOG00000032004
UniProtKB: Q9JJ02

Process Predictions
Disease Predictions

Cyp2b21 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of transport	GO:0051050	245	0.270
synaptic transmission	GO:0007268	235	0.262
positive regulation of multicellular organismal process	GO:0051240	387	0.225
cation transmembrane transport	GO:0098655	263	0.224
sodium ion transport	GO:0006814	82	0.165
regulation of cell proliferation	GO:0042127	359	0.145
response to wounding	GO:0009611	254	0.141
positive regulation of signaling	GO:0023056	270	0.130
cell cell signaling	GO:0007267	335	0.104
feeding behavior	GO:0007631	53	0.095
regulation of synaptic transmission	GO:0050804	141	0.093
regulation of multicellular organismal development	GO:2000026	376	0.085
positive regulation of nervous system development	GO:0051962	178	0.083
regulation of cellular localization	GO:0060341	263	0.078
catecholamine transport	GO:0051937	37	0.075
positive regulation of neurogenesis	GO:0050769	165	0.075
alkaloid metabolic process	GO:0009820	3	0.071	Rat
positive regulation of cellular component organization	GO:0051130	200	0.061
transmembrane transport	GO:0055085	412	0.061
regulation of phosphate metabolic process	GO:0019220	349	0.061
single organism organelle organization	GO:1902589	180	0.060
response to cesium ion	GO:0010164	2	0.060	Rat
response to peptide	GO:1901652	292	0.059	Rat
cation transport	GO:0006812	382	0.058
ion homeostasis	GO:0050801	212	0.058
arachidonic acid metabolic process	GO:0019369	20	0.057	Rat
carboxylic acid metabolic process	GO:0019752	289	0.056	Rat
hormone transport	GO:0009914	121	0.055
signal release	GO:0023061	145	0.055
regulation of rna metabolic process	GO:0051252	391	0.054
positive regulation of cell proliferation	GO:0008284	249	0.053
oxoacid metabolic process	GO:0043436	290	0.053	Rat
regulation of cell differentiation	GO:0045595	320	0.053
reproductive process	GO:0022414	372	0.052	Rat
regulation of phosphorus metabolic process	GO:0051174	349	0.052
regulation of amine transport	GO:0051952	54	0.052
regulation of neurogenesis	GO:0050767	247	0.050
rhythmic process	GO:0048511	156	0.049
halogenated hydrocarbon metabolic process	GO:0042197	4	0.049	Rat
protein complex subunit organization	GO:0071822	302	0.047
positive regulation of biosynthetic process	GO:0009891	319	0.046
negative regulation of signaling	GO:0023057	157	0.046
defense response	GO:0006952	194	0.046
regulation of signal transduction	GO:0009966	318	0.045
positive regulation of cell differentiation	GO:0045597	217	0.044
regulation of secretion	GO:0051046	224	0.043
response to oxidative stress	GO:0006979	186	0.043	Rat
purine ribonucleotide metabolic process	GO:0009150	227	0.043
amino acid transport	GO:0006865	70	0.042
regulation of transcription dna templated	GO:0006355	374	0.042
calcitriol biosynthetic process from calciol	GO:0036378	2	0.041
g protein coupled purinergic nucleotide receptor signaling pathway	GO:0035589	3	0.041
cellular response to stress	GO:0033554	269	0.041
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.041
regulation of protein metabolic process	GO:0051246	289	0.041
positive regulation of molecular function	GO:0044093	230	0.040
cation homeostasis	GO:0055080	195	0.038
regulation of nervous system development	GO:0051960	264	0.038
regulation of molecular function	GO:0065009	398	0.037
positive regulation of gene expression	GO:0010628	244	0.037
negative regulation of vesicle fusion	GO:0031339	2	0.036
organic acid transport	GO:0015849	116	0.036
neuron death	GO:0070997	127	0.035
regulation of protein phosphorylation	GO:0001932	183	0.035
positive regulation of cell communication	GO:0010647	271	0.035
negative regulation of secretion	GO:0051048	82	0.035
cellular homeostasis	GO:0019725	252	0.034
divalent metal ion transport	GO:0070838	132	0.034
secretion	GO:0046903	307	0.034
response to nutrient levels	GO:0031667	370	0.034
response to estrogen	GO:0043627	232	0.034
metal ion transport	GO:0030001	289	0.033
positive regulation of synaptic transmission	GO:0050806	62	0.033
cellular component biogenesis	GO:0044085	368	0.032
regulation of nucleotide metabolic process	GO:0006140	117	0.032
response to oxygen levels	GO:0070482	265	0.032
metal ion homeostasis	GO:0055065	186	0.032
anatomical structure morphogenesis	GO:0009653	298	0.032
positive regulation of developmental process	GO:0051094	283	0.031
cellular component movement	GO:0006928	248	0.031
cellular metal ion homeostasis	GO:0006875	172	0.031
anion transport	GO:0006820	178	0.031
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.031
vesicle mediated transport	GO:0016192	181	0.031
secretion by cell	GO:0032940	248	0.030
blood vessel morphogenesis	GO:0048514	58	0.030
carboxylic acid transport	GO:0046942	115	0.030
response to inorganic substance	GO:0010035	377	0.030	Rat
neuron differentiation	GO:0030182	368	0.030
regulation of cellular component movement	GO:0051270	150	0.030
negative regulation of gene expression	GO:0010629	199	0.029
organic anion transport	GO:0015711	132	0.029
response to ketone	GO:1901654	182	0.029	Rat
neuron projection development	GO:0031175	273	0.029
localization of cell	GO:0051674	202	0.029
nucleobase containing small molecule metabolic process	GO:0055086	316	0.029
cellular chemical homeostasis	GO:0055082	247	0.028
response to alkaloid	GO:0043279	132	0.028
cellular cation homeostasis	GO:0030003	180	0.028
inorganic ion transmembrane transport	GO:0098660	229	0.028
chlorinated hydrocarbon metabolic process	GO:0042196	4	0.028	Rat
response to decreased oxygen levels	GO:0036293	237	0.028
cellular ion homeostasis	GO:0006873	184	0.028
regulation of cellular protein metabolic process	GO:0032268	267	0.028
icosanoid metabolic process	GO:0006690	38	0.027	Rat
carbohydrate derivative metabolic process	GO:1901135	346	0.027
regulation of neuron projection development	GO:0010975	161	0.027
response to peptide hormone	GO:0043434	278	0.027	Rat
regulation of hormone levels	GO:0010817	187	0.027
reproduction	GO:0000003	245	0.026
nucleic acid templated transcription	GO:0097659	379	0.026
detection of chemical stimulus involved in sensory perception of bitter taste	GO:0001580	4	0.026
cell projection organization	GO:0030030	302	0.025
regulation of system process	GO:0044057	208	0.025
neuron development	GO:0048666	286	0.025
regulation of ion transport	GO:0043269	245	0.025
positive regulation of phosphorus metabolic process	GO:0010562	262	0.025
regulation of response to stress	GO:0080134	126	0.025
ribose phosphate metabolic process	GO:0019693	235	0.024
positive regulation of neuron differentiation	GO:0045666	126	0.024
positive regulation of protein metabolic process	GO:0051247	178	0.024
positive regulation of secretion	GO:0051047	140	0.024
central nervous system development	GO:0007417	311	0.024
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.024
regulation of cell migration	GO:0030334	128	0.024
ion transmembrane transport	GO:0034220	365	0.024
regulation of nucleic acid templated transcription	GO:1903506	380	0.024
organic hydroxy compound biosynthetic process	GO:1901617	51	0.024	Rat
negative regulation of cell communication	GO:0010648	158	0.024
macromolecule localization	GO:0033036	252	0.024
response to bacterium	GO:0009617	200	0.024
macromolecular complex assembly	GO:0065003	273	0.023
regulation of phosphatidylinositol dephosphorylation	GO:0060304	1	0.023
growth	GO:0040007	165	0.023
nitrogen compound transport	GO:0071705	229	0.023
circulatory system process	GO:0003013	183	0.023
regulation of apoptotic process	GO:0042981	335	0.023
regulation of rna biosynthetic process	GO:2001141	381	0.023
sensory perception	GO:0007600	101	0.023
circulatory system development	GO:0072359	134	0.022
actin filament based process	GO:0030029	86	0.022
response to hypoxia	GO:0001666	231	0.022
regulation of homeostatic process	GO:0032844	101	0.022
regulation of response to external stimulus	GO:0032101	106	0.022
negative regulation of transport	GO:0051051	136	0.022
sodium ion transmembrane transport	GO:0035725	67	0.022
detection of chemical stimulus	GO:0009593	10	0.022
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.022
positive regulation of ion transport	GO:0043270	94	0.022
chemical homeostasis	GO:0048878	292	0.022
protein complex biogenesis	GO:0070271	263	0.022
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.021
response to mechanical stimulus	GO:0009612	134	0.021
dicarboxylic acid metabolic process	GO:0043648	42	0.021
regulation of heart contraction	GO:0008016	48	0.021
protein phosphorylation	GO:0006468	345	0.021
positive regulation of nucleotide metabolic process	GO:0045981	91	0.020
macromolecular complex subunit organization	GO:0043933	339	0.020
vasculature development	GO:0001944	70	0.020
positive regulation of leukocyte activation	GO:0002696	30	0.020
nucleoside phosphate metabolic process	GO:0006753	283	0.020
response to growth factor	GO:0070848	189	0.020
organelle organization	GO:0006996	266	0.020
regulation of peptide secretion	GO:0002791	82	0.020
phenol containing compound biosynthetic process	GO:0046189	9	0.020	Rat
regulation of neuron differentiation	GO:0045664	208	0.020
trichloroethylene metabolic process	GO:0018979	1	0.020	Rat
apoptotic process	GO:0006915	381	0.020
regulation of secretion by cell	GO:1903530	208	0.020
negative regulation of metabolic process	GO:0009892	331	0.019
blood circulation	GO:0008015	183	0.019
purine nucleotide metabolic process	GO:0006163	229	0.019
positive regulation of phosphate metabolic process	GO:0045937	262	0.019
transcription from rna polymerase ii promoter	GO:0006366	252	0.019
g protein coupled receptor signaling pathway	GO:0007186	242	0.019
naphthalene metabolic process	GO:0018931	2	0.019	Rat
potassium ion homeostasis	GO:0055075	2	0.019
ribonucleotide metabolic process	GO:0009259	231	0.019
positive regulation of cellular biosynthetic process	GO:0031328	295	0.019
dopamine metabolic process	GO:0042417	12	0.019	Rat
positive regulation of action potential	GO:0045760	8	0.019
organophosphate metabolic process	GO:0019637	370	0.019
multi organism reproductive process	GO:0044703	262	0.018	Rat
behavior	GO:0007610	205	0.018
fatty acid derivative metabolic process	GO:1901568	38	0.018	Rat
digestive system process	GO:0022600	24	0.018
fat cell proliferation	GO:0070341	2	0.018
monoamine transport	GO:0015844	43	0.018
neurological system process	GO:0050877	219	0.018
regulation of cellular component organization	GO:0051128	368	0.018
muscle cell proliferation	GO:0033002	84	0.018
regulation of metal ion transport	GO:0010959	118	0.018
regulation of cellular amine metabolic process	GO:0033238	8	0.018
action potential	GO:0001508	54	0.018
cellular response to oxygen containing compound	GO:1901701	386	0.018
inorganic cation transmembrane transport	GO:0098662	202	0.018
cellular response to endogenous stimulus	GO:0071495	377	0.017
peptidyl tyrosine phosphorylation	GO:0018108	72	0.017
protein complex assembly	GO:0006461	263	0.017
cellular amino acid metabolic process	GO:0006520	107	0.017
peristalsis	GO:0030432	2	0.017
amine metabolic process	GO:0009308	38	0.017
positive regulation of cell development	GO:0010720	176	0.017
multicellular organismal homeostasis	GO:0048871	49	0.017
regulation of cell motility	GO:2000145	131	0.017
positive regulation of intracellular signal transduction	GO:1902533	138	0.017
regulation of canonical wnt signaling pathway	GO:0060828	4	0.016
cytoskeleton organization	GO:0007010	111	0.016
inflammatory response	GO:0006954	150	0.016
intracellular signal transduction	GO:0035556	314	0.016
regeneration	GO:0031099	163	0.016
aging	GO:0007568	241	0.016	Rat
cell migration	GO:0016477	197	0.016
divalent inorganic cation transport	GO:0072511	134	0.016
response to other organism	GO:0051707	220	0.016
regulation of peptide transport	GO:0090087	87	0.016
response to molecule of bacterial origin	GO:0002237	194	0.016
multicellular organismal reproductive process	GO:0048609	233	0.016
single organism reproductive process	GO:0044702	297	0.016
brain development	GO:0007420	247	0.016
multi multicellular organism process	GO:0044706	138	0.016	Rat
amine transport	GO:0015837	57	0.015
negative regulation of secretion by cell	GO:1903531	72	0.015
cardiovascular system development	GO:0072358	134	0.015
negative regulation of cellular metabolic process	GO:0031324	281	0.015
endoplasmic reticulum membrane organization	GO:0090158	1	0.015
positive regulation of cellular amine metabolic process	GO:0033240	3	0.015
immune system process	GO:0002376	204	0.015
purine containing compound metabolic process	GO:0072521	253	0.015
blood vessel development	GO:0001568	69	0.015
regulation of cell development	GO:0060284	263	0.015
regulation of neuron death	GO:1901214	115	0.015
locomotion	GO:0040011	237	0.015
cellular response to organic cyclic compound	GO:0071407	202	0.015
hormone secretion	GO:0046879	115	0.015
fatty acid metabolic process	GO:0006631	99	0.015	Rat
nucleoside triphosphate metabolic process	GO:0009141	144	0.015
regulation of hormone secretion	GO:0046883	106	0.014
neuronal ion channel clustering	GO:0045161	3	0.014
negative regulation of amine transport	GO:0051953	24	0.014
cellular amine metabolic process	GO:0044106	38	0.014
sensory perception of bitter taste	GO:0050913	4	0.014
negative regulation of macromolecule metabolic process	GO:0010605	260	0.014
negative regulation of cell death	GO:0060548	229	0.014
potassium ion transmembrane transport	GO:0071805	71	0.014
positive regulation of catalytic activity	GO:0043085	184	0.014
regulation of hydrolase activity	GO:0051336	143	0.014
defense response to gram negative bacterium	GO:0050829	3	0.014
positive regulation of phosphorylation	GO:0042327	177	0.014
regulation of phosphorylation	GO:0042325	248	0.014
response to ethanol	GO:0045471	162	0.014	Rat
defecation	GO:0030421	1	0.013
positive regulation of blood circulation	GO:1903524	65	0.013
regulation of immune system process	GO:0002682	123	0.013
positive regulation of cellular protein metabolic process	GO:0032270	167	0.013
spermatogenesis	GO:0007283	99	0.013
homeostatic process	GO:0042592	331	0.013
monovalent inorganic cation homeostasis	GO:0055067	36	0.013
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.013
pancreatic a cell differentiation	GO:0003310	1	0.013
calcium ion homeostasis	GO:0055074	162	0.013
male sex differentiation	GO:0046661	64	0.013
rna metabolic process	GO:0016070	406	0.013
positive regulation of programmed cell death	GO:0043068	157	0.013
gamete generation	GO:0007276	124	0.013
acute inflammatory response	GO:0002526	58	0.013
positive regulation of protein phosphorylation	GO:0001934	135	0.013
response to cytokine	GO:0034097	215	0.013
single organism biosynthetic process	GO:0044711	342	0.013
regulation of cellular ketone metabolic process	GO:0010565	27	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.013
organic hydroxy compound metabolic process	GO:1901615	115	0.013	Rat
positive regulation of signal transduction	GO:0009967	175	0.013
regulation of muscle contraction	GO:0006937	53	0.013
regulation of cyclic nucleotide biosynthetic process	GO:0030802	45	0.012
response to reactive oxygen species	GO:0000302	120	0.012	Rat
urinary tract smooth muscle contraction	GO:0014848	4	0.012
hormone metabolic process	GO:0042445	69	0.012
regulation of heart rate	GO:0002027	16	0.012
urinary bladder smooth muscle contraction	GO:0014832	4	0.012
oligopeptide transport	GO:0006857	4	0.012
actin mediated cell contraction	GO:0070252	12	0.012
head development	GO:0060322	247	0.012
fertilization	GO:0009566	3	0.012
peptide transport	GO:0015833	97	0.012
regulation of neuron apoptotic process	GO:0043523	83	0.012
acylglycerol metabolic process	GO:0006639	21	0.012	Rat
amide transport	GO:0042886	105	0.012
multicellular organism reproduction	GO:0032504	233	0.012
vesicle organization	GO:0016050	29	0.012
regulation of programmed cell death	GO:0043067	341	0.012
positive regulation of saliva secretion	GO:0046878	3	0.012
cellular response to organonitrogen compound	GO:0071417	197	0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	51	0.012
catecholamine secretion	GO:0050432	33	0.012
positive regulation of response to stimulus	GO:0048584	285	0.012
regulation of protein kinase activity	GO:0045859	105	0.012
monovalent inorganic cation transport	GO:0015672	172	0.012
nucleoside metabolic process	GO:0009116	179	0.011
endoplasmic reticulum organization	GO:0007029	1	0.011
purine ribonucleotide biosynthetic process	GO:0009152	81	0.011
regulation of defense response	GO:0031347	68	0.011
wound healing	GO:0042060	122	0.011
positive regulation of homeostatic process	GO:0032846	49	0.011
cell type specific apoptotic process	GO:0097285	134	0.011
regulation of membrane potential	GO:0042391	110	0.011
positive regulation of protein modification process	GO:0031401	142	0.011
negative regulation of long term synaptic potentiation	GO:1900272	1	0.011
muscle contraction	GO:0006936	88	0.011
male gamete generation	GO:0048232	99	0.011
response to glucocorticoid	GO:0051384	223	0.011
negative regulation of cell proliferation	GO:0008285	119	0.011
response to extracellular stimulus	GO:0009991	380	0.011
positive regulation of secretion by cell	GO:1903532	128	0.011
negative regulation of ion transport	GO:0043271	51	0.011
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.011
lipid storage	GO:0019915	1	0.011
cellular component morphogenesis	GO:0032989	155	0.011
regulation of leukocyte activation	GO:0002694	45	0.011
transcription dna templated	GO:0006351	377	0.011
negative regulation of cellular biosynthetic process	GO:0031327	161	0.011
cellular protein localization	GO:0034613	122	0.011
erk1 and erk2 cascade	GO:0070371	48	0.011
positive regulation of amine transport	GO:0051954	26	0.011
second messenger mediated signaling	GO:0019932	51	0.011
cardiac conduction	GO:0061337	2	0.011
regulation of organic acid transport	GO:0032890	35	0.011
regulation of growth	GO:0040008	105	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.011
hematopoietic or lymphoid organ development	GO:0048534	36	0.011
cellular protein complex assembly	GO:0043623	44	0.010
regulation of calcium ion transport	GO:0051924	77	0.010
negative regulation of molecular function	GO:0044092	133	0.010
regulation of saliva secretion	GO:0046877	3	0.010
regulation of action potential	GO:0098900	14	0.010
sexual reproduction	GO:0019953	148	0.010
anterior posterior pattern specification	GO:0009952	1	0.010
regulation of protein modification process	GO:0031399	194	0.010
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.010
muscle system process	GO:0003012	115	0.010
protein oligomerization	GO:0051259	191	0.010
negative regulation of response to stimulus	GO:0048585	155	0.010
response to external biotic stimulus	GO:0043207	221	0.010
rna biosynthetic process	GO:0032774	380	0.010
regulation of purine nucleotide metabolic process	GO:1900542	115	0.010
angiotensin mediated drinking behavior	GO:0003051	2	0.010
regulation of peptide hormone secretion	GO:0090276	80	0.010
cellular macromolecule localization	GO:0070727	122	0.010
epoxygenase p450 pathway	GO:0019373	1	0.010	Rat
response to carbohydrate	GO:0009743	183	0.010

Cyp2b21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.012
disease of anatomical entity	DOID:7	0.012
nervous system disease	DOID:863	0.011

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