Rattus norvegicus

0 known processes

Capn8

calpain 8

(Aliases: Cls4,CL-2',nCL-2)

Capn8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to peptideGO:19016522920.350
rna biosynthetic processGO:00327743800.319
response to metal ionGO:00100382530.291
Rat
anion transportGO:00068201780.256
positive regulation of multicellular organismal processGO:00512403870.240
positive regulation of cell deathGO:00109421840.202
Worm
response to peptide hormoneGO:00434342780.199
brain developmentGO:00074202470.196
response to nutrient levelsGO:00316673700.192
reproductive processGO:00224143720.190
transcription dna templatedGO:00063513770.189
response to organophosphorusGO:00466831020.188
response to extracellular stimulusGO:00099913800.185
positive regulation of nitrogen compound metabolic processGO:00511733340.166
response to purine containing compoundGO:00140741260.163
response to corticosteroidGO:00319602350.162
regulation of rna metabolic processGO:00512523910.160
regulation of nucleic acid templated transcriptionGO:19035063800.159
regulation of neurogenesisGO:00507672470.144
carboxylic acid transportGO:00469421150.136
regulation of rna biosynthetic processGO:20011413810.133
positive regulation of developmental processGO:00510942830.131
neuron developmentGO:00486662860.130
positive regulation of cellular biosynthetic processGO:00313282950.127
cellular homeostasisGO:00197252520.125
regenerationGO:00310991630.122
circulatory system processGO:00030131830.121
programmed cell deathGO:00125013920.120
cellular component assemblyGO:00226073600.117
regulation of system processGO:00440572080.116
central nervous system developmentGO:00074173110.115
blood circulationGO:00080151830.114
regulation of nervous system developmentGO:00519602640.107
reproductive system developmentGO:00614581280.106
response to amino acidGO:0043200750.106
Rat
cellular response to hormone stimulusGO:00328702470.106
nucleic acid templated transcriptionGO:00976593790.105
cellular chemical homeostasisGO:00550822470.105
gland developmentGO:00487321550.103
response to cytokineGO:00340972150.102
transmembrane transportGO:00550854120.100
positive regulation of nervous system developmentGO:00519621780.100
response to ketoneGO:19016541820.098
response to glucocorticoidGO:00513842230.098
secretionGO:00469033070.094
regulation of neuron differentiationGO:00456642080.092
ion transmembrane transportGO:00342203650.092
oxoacid metabolic processGO:00434362900.088
cellular component biogenesisGO:00440853680.086
rna metabolic processGO:00160704060.086
carbohydrate derivative metabolic processGO:19011353460.085
regulation of transcription from rna polymerase ii promoterGO:00063572340.084
carboxylic acid metabolic processGO:00197522890.083
positive regulation of apoptotic processGO:00430651540.083
regulation of cell developmentGO:00602842630.082
chemical homeostasisGO:00488782920.082
negative regulation of nucleobase containing compound metabolic processGO:00459341530.082
apoptotic processGO:00069153810.081
cellular cation homeostasisGO:00300031800.080
protein maturationGO:0051604680.080
Rat
cellular response to organic cyclic compoundGO:00714072020.079
immune system processGO:00023762040.079
organic acid metabolic processGO:00060822920.079
cell projection organizationGO:00300303020.078
cellular response to alkaloidGO:0071312250.078
regulation of cell differentiationGO:00455953200.077
cation transportGO:00068123820.076
response to alkaloidGO:00432791320.075
regulation of ion transportGO:00432692450.074
metal ion transportGO:00300012890.074
regulation of ion transmembrane transportGO:00347651210.072
positive regulation of programmed cell deathGO:00430681570.072
wound healingGO:00420601220.070
negative regulation of neuron differentiationGO:0045665620.067
positive regulation of rna biosynthetic processGO:19026801970.066
acid secretionGO:0046717480.066
homeostatic processGO:00425923310.066
negative regulation of rna biosynthetic processGO:19026791180.066
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163520.064
positive regulation of cell developmentGO:00107201760.061
positive regulation of ion transportGO:0043270940.061
regulation of protein metabolic processGO:00512462890.061
positive regulation of cellular component organizationGO:00511302000.060
cardiovascular system developmentGO:00723581340.060
organic anion transportGO:00157111320.060
divalent inorganic cation homeostasisGO:00725071650.058
regulation of cell proliferationGO:00421273590.058
positive regulation of response to stimulusGO:00485842850.057
positive regulation of nucleic acid templated transcriptionGO:19035081970.057
transcription from rna polymerase ii promoterGO:00063662520.057
organophosphate metabolic processGO:00196373700.054
macromolecular complex assemblyGO:00650032730.054
regulation of molecular functionGO:00650093980.054
proteolysisGO:00065081750.053
Rat
head developmentGO:00603222470.052
calcium ion importGO:0070509220.052
response to mineralocorticoidGO:0051385490.052
anatomical structure morphogenesisGO:00096532980.051
positive regulation of nucleobase containing compound metabolic processGO:00459353190.051
negative regulation of gene expressionGO:00106291990.051
cellular calcium ion homeostasisGO:00068741600.051
growthGO:00400071650.051
positive regulation of macromolecule biosynthetic processGO:00105572470.050
regulation of programmed cell deathGO:00430673410.050
positive regulation of cell differentiationGO:00455972170.049
regulation of cellular component organizationGO:00511283680.049
positive regulation of biosynthetic processGO:00098913190.049
organic acid transportGO:00158491160.049
ion homeostasisGO:00508012120.049
cellular lipid metabolic processGO:00442552080.048
regulation of secretionGO:00510462240.048
response to external biotic stimulusGO:00432072210.048
response to carbohydrateGO:00097431830.047
regulation of multicellular organismal developmentGO:20000263760.047
positive regulation of gene expressionGO:00106282440.046
negative regulation of transcription dna templatedGO:00458921160.046
response to inorganic substanceGO:00100353770.046
Rat
response to estradiolGO:00323551640.045
axon developmentGO:0061564960.045
peptidyl tyrosine phosphorylationGO:0018108720.045
cellular response to endogenous stimulusGO:00714953770.045
Rat
nitrogen compound transportGO:00717052290.044
transmission of nerve impulseGO:0019226420.044
cation homeostasisGO:00550801950.044
forebrain developmentGO:0030900980.043
regulation of transcription dna templatedGO:00063553740.043
negative regulation of nitrogen compound metabolic processGO:00511721610.043
positive regulation of neurogenesisGO:00507691650.042
cellular response to nitrogen compoundGO:19016992100.042
Rat
multicellular organismal signalingGO:0035637440.042
cellular response to stressGO:00335542690.042
multicellular organismal reproductive processGO:00486092330.041
response to lipopolysaccharideGO:00324961910.041
cellular metal ion homeostasisGO:00068751720.041
positive regulation of transportGO:00510502450.041
response to estrogenGO:00436272320.040
response to oxygen levelsGO:00704822650.039
Rat
potassium ion transportGO:0006813970.039
purine nucleotide metabolic processGO:00061632290.038
positive regulation of molecular functionGO:00440932300.038
macromolecular complex subunit organizationGO:00439333390.038
negative regulation of rna metabolic processGO:00512531230.038
purine ribonucleotide metabolic processGO:00091502270.038
cellular response to oxygen containing compoundGO:19017013860.038
Rat
cellular response to alcoholGO:0097306870.037
fatty acid biosynthetic processGO:0006633330.037
circulatory system developmentGO:00723591340.037
response to nutrientGO:00075842480.036
regulation of apoptotic processGO:00429813350.036
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.036
carboxylic acid biosynthetic processGO:0046394830.036
cellular response to growth factor stimulusGO:00713631620.035
cellular amine metabolic processGO:0044106380.035
regulation of cell projection organizationGO:00313441750.035
urogenital system developmentGO:0001655780.035
tissue developmentGO:00098882520.035
multicellular organism reproductionGO:00325042330.035
negative regulation of cellular biosynthetic processGO:00313271610.034
positive regulation of gastric acid secretionGO:006045420.034
protein complex subunit organizationGO:00718223020.034
regulation of synaptic transmissionGO:00508041410.034
regulation of cellular ketone metabolic processGO:0010565270.033
response to acid chemicalGO:00011012220.032
Rat
gliogenesisGO:0042063930.032
cellular response to acid chemicalGO:0071229750.032
Rat
monocarboxylic acid transportGO:0015718520.032
protein processingGO:0016485680.032
Rat
negative regulation of macromolecule metabolic processGO:00106052600.032
regulation of catalytic activityGO:00507903040.031
purine containing compound metabolic processGO:00725212530.031
response to woundingGO:00096112540.031
action potentialGO:0001508540.031
calcium ion homeostasisGO:00550741620.031
negative regulation of cell communicationGO:00106481580.031
negative regulation of multicellular organismal processGO:00512412030.030
purine nucleotide biosynthetic processGO:0006164830.030
protein complex biogenesisGO:00702712630.030
positive regulation of cytosolic calcium ion concentrationGO:00072041220.030
regulation of signal transductionGO:00099663180.030
carbohydrate metabolic processGO:00059751300.030
cellular divalent inorganic cation homeostasisGO:00725031620.030
response to monosaccharideGO:00342841590.029
response to growth factorGO:00708481890.029
positive regulation of transcription dna templatedGO:00458931970.029
positive regulation of rna metabolic processGO:00512542030.029
cellular response to lipidGO:00713962010.028
protein phosphorylationGO:00064683450.028
organelle organizationGO:00069962660.028
response to transition metal nanoparticleGO:19902671220.028
protein homooligomerizationGO:0051260910.028
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.028
renal system processGO:0003014400.028
cellular response to steroid hormone stimulusGO:0071383930.028
organic acid biosynthetic processGO:0016053830.027
inorganic cation transmembrane transportGO:00986622020.027
inflammatory responseGO:00069541500.027
negative regulation of biosynthetic processGO:00098901680.027
single organism reproductive processGO:00447022970.027
synaptic transmissionGO:00072682350.027
response to insulinGO:00328681330.027
amine metabolic processGO:0009308380.027
negative regulation of macromolecule biosynthetic processGO:00105581480.027
purine ribonucleoside triphosphate catabolic processGO:00092071220.026
response to osmotic stressGO:0006970420.026
regulation of cellular amine metabolic processGO:003323880.026
cell cell signalingGO:00072673350.026
positive regulation of cell communicationGO:00106472710.026
response to hexoseGO:00097461440.026
lipid biosynthetic processGO:00086101280.025
negative regulation of nucleic acid templated transcriptionGO:19035071170.025
positive regulation of cellular amino acid metabolic processGO:004576410.025
organ morphogenesisGO:0009887750.025
nucleotide metabolic processGO:00091172790.025
neuron differentiationGO:00301823680.025
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.025
regulation of secretion by cellGO:19035302080.025
cellular amide metabolic processGO:0043603440.025
negative regulation of cellular metabolic processGO:00313242810.025
regulation of phosphorus metabolic processGO:00511743490.025
regulation of phosphorylationGO:00423252480.025
catabolic processGO:00090563510.025
mapk cascadeGO:00001651400.024
peptidyl tyrosine modificationGO:0018212720.024
long chain fatty acid transportGO:0015909140.024
positive regulation of signal transductionGO:00099671750.024
response to tumor necrosis factorGO:0034612560.024
intracellular signal transductionGO:00355563140.024
ras protein signal transductionGO:0007265290.024
cellular catabolic processGO:00442482950.023
nucleotide biosynthetic processGO:0009165980.023
heart contractionGO:0060047570.023
regulation of anatomical structure sizeGO:00900661350.023
regulation of neuron projection developmentGO:00109751610.023
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.023
neuron deathGO:00709971270.023
neurotransmitter uptakeGO:000150430.023
protein oligomerizationGO:00512591910.023
negative regulation of apoptotic processGO:00430661810.023
cellular ion homeostasisGO:00068731840.022
neuron neuron synaptic transmissionGO:0007270600.022
multi organism reproductive processGO:00447032620.022
g protein coupled receptor signaling pathwayGO:00071862420.022
metal ion homeostasisGO:00550651860.022
response to corticosteroneGO:0051412400.022
behaviorGO:00076102050.022
regulation of calcium ion transportGO:0051924770.022
cognitionGO:0050890920.022
response to campGO:0051591910.021
developmental process involved in reproductionGO:00030061590.021
cellular response to metal ionGO:0071248550.021
endocrine system developmentGO:0035270300.021
regulation of membrane potentialGO:00423911100.021
cellular response to gonadotropin stimulusGO:0071371170.021
cytosolic calcium ion homeostasisGO:00514801400.021
lipid localizationGO:0010876620.021
single organism catabolic processGO:00447122830.021
neuronal action potentialGO:0019228350.021
cation transmembrane transportGO:00986552630.021
cellular response to insulin stimulusGO:0032869810.021
nucleoside phosphate metabolic processGO:00067532830.021
heart developmentGO:0007507720.020
organic substance catabolic processGO:19015753160.020
female pregnancyGO:00075651220.020
regulation of cellular amino acid metabolic processGO:000652120.020
positive regulation of cell projection organizationGO:00313461110.020
lipid storageGO:001991510.020
neuron projection developmentGO:00311752730.020
intracellular transportGO:00469071850.020
nucleobase containing small molecule metabolic processGO:00550863160.020
cellular response to drugGO:0035690300.020
inorganic ion transmembrane transportGO:00986602290.019
response to biotic stimulusGO:00096072260.019
cardiac cell developmentGO:0055006160.019
epithelium developmentGO:0060429960.019
positive regulation of cell proliferationGO:00082842490.019
cellular response to glucose stimulusGO:0071333650.019
cellular response to organonitrogen compoundGO:00714171970.019
Rat
small gtpase mediated signal transductionGO:0007264360.019
cardiac chamber developmentGO:000320510.019
cellular amino acid metabolic processGO:00065201070.019
negative regulation of metabolic processGO:00098923310.019
positive regulation of long term synaptic potentiationGO:190027340.019
regulation of reactive oxygen species biosynthetic processGO:190342650.018
regulation of cell growthGO:0001558850.018
positive regulation of protein modification processGO:00314011420.018
heart processGO:0003015570.018
negative regulation of growthGO:0045926370.018
steroid biosynthetic processGO:0006694480.018
telencephalon developmentGO:0021537620.018
regulation of lyase activityGO:0051339220.018
ribonucleotide metabolic processGO:00092592310.018
response to vitaminGO:00332731310.018
single organism biosynthetic processGO:00447113420.018
regulation of lipid biosynthetic processGO:0046890380.018
muscle system processGO:00030121150.018
macromolecule localizationGO:00330362520.018
nucleoside monophosphate catabolic processGO:0009125560.018
reproductionGO:00000032450.017
nucleoside phosphate biosynthetic processGO:19012931020.017
negative regulation of cell developmentGO:0010721820.017
cytoplasmic transportGO:00164821150.017
negative regulation of neuron projection developmentGO:0010977460.017
ribonucleoside triphosphate metabolic processGO:00091991410.017
androgen metabolic processGO:0008209140.017
purine nucleoside triphosphate metabolic processGO:00091441410.017
negative regulation of response to stimulusGO:00485851550.017
carbohydrate homeostasisGO:0033500750.017
ribonucleoside triphosphate catabolic processGO:00092031220.016
neurological system processGO:00508772190.016
positive regulation of phosphate metabolic processGO:00459372620.016
ribose phosphate metabolic processGO:00196932350.016
response to calcium ionGO:0051592590.016
Rat
l glutamate importGO:005193820.016
kidney developmentGO:0001822670.016
regulation of nucleotide metabolic processGO:00061401170.016
positive regulation of mapk cascadeGO:0043410920.016
defense responseGO:00069521940.016
regulation of growthGO:00400081050.016
response to cadmium ionGO:0046686350.016
regulation of cellular catabolic processGO:00313291010.016
liver developmentGO:0001889900.016
regulation of reactive oxygen species metabolic processGO:2000377260.016
connective tissue developmentGO:0061448330.016
positive regulation of intracellular signal transductionGO:19025331380.016
cellular response to lipopolysaccharideGO:0071222550.016
glucose homeostasisGO:0042593750.016
reactive nitrogen species metabolic processGO:200105710.015
dicarboxylic acid transportGO:0006835340.015
cellular ketone metabolic processGO:0042180510.015
reactive oxygen species biosynthetic processGO:190340980.015
positive regulation of neuron differentiationGO:00456661260.015
response to molecule of bacterial originGO:00022371940.015
male sex differentiationGO:0046661640.015
response to ammonium ionGO:0060359710.015
negative regulation of cellular component organizationGO:0051129830.015
tissue regenerationGO:0042246360.015
positive regulation of neuron projection developmentGO:0010976990.015
hindbrain morphogenesisGO:002157520.015
cellular response to inorganic substanceGO:0071241650.015
regulation of phosphate metabolic processGO:00192203490.015
reproductive structure developmentGO:00486081280.015
tube developmentGO:0035295890.014
regulation of hormone levelsGO:00108171870.014
sequestering of calcium ionGO:005120880.014
unsaturated fatty acid biosynthetic processGO:0006636210.014
regulation of jnk cascadeGO:0046328190.014
cellular component movementGO:00069282480.014
purine ribonucleoside triphosphate metabolic processGO:00092051400.014
regulation of transmembrane transportGO:00347621220.014
response to amineGO:0014075460.014
protein secretionGO:0009306340.014
camp metabolic processGO:0046058630.014
lipid metabolic processGO:00066292830.014
heart morphogenesisGO:000300730.014
positive regulation of cellular amine metabolic processGO:003324030.014
positive regulation of kinase activityGO:0033674770.014
digestionGO:0007586260.014
response to bacteriumGO:00096172000.014
neurotransmitter transportGO:0006836420.014
negative regulation of protein processingGO:0010955470.014
androgen biosynthetic processGO:0006702100.014
pancreas developmentGO:0031016190.014
positive regulation of the force of heart contraction by norepinephrineGO:000306110.014
cellular nitrogen compound catabolic processGO:00442701630.013
positive regulation of protein metabolic processGO:00512471780.013
positive regulation of phosphorus metabolic processGO:00105622620.013
muscle cell differentiationGO:0042692520.013
single organism intracellular transportGO:19025821660.013
amino acid transportGO:0006865700.013
immune responseGO:00069551040.013
cell cycleGO:00070491010.013
regulation of protein phosphorylationGO:00019321830.013
cellular response to tumor necrosis factorGO:0071356460.013
lipid transportGO:0006869610.013
endocardial cushion developmentGO:000319710.013
molting cycle processGO:002240420.013
negative regulation of molecular functionGO:00440921330.013
nucleoside phosphate catabolic processGO:19012921400.013
positive regulation of homeostatic processGO:0032846490.013
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.013
positive regulation of transferase activityGO:0051347810.013
regulation of cyclase activityGO:0031279210.013
gtp metabolic processGO:0046039720.013
regulation of metal ion transportGO:00109591180.013
regulation of heart contractionGO:0008016480.012
purine containing compound biosynthetic processGO:0072522850.012
regulation of protein processingGO:0070613500.012
somatostatin receptor signaling pathwayGO:003816940.012
ribonucleoside catabolic processGO:00424541260.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
cellular response to monosaccharide stimulusGO:0071326670.012
single organism cellular localizationGO:19025801020.012
locomotionGO:00400112370.012
ribonucleoside metabolic processGO:00091191740.012
hexose metabolic processGO:0019318580.012
ribonucleotide biosynthetic processGO:0009260850.012
agingGO:00075682410.012
actin filament based movementGO:0030048160.012
glucose metabolic processGO:0006006520.012
response to decreased oxygen levelsGO:00362932370.012
Rat
response to reactive oxygen speciesGO:00003021200.012
single organism behaviorGO:00447081300.012
cardiocyte differentiationGO:0035051220.012
divalent metal ion transportGO:00708381320.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
regulation of neurological system processGO:0031644430.012
regulation of cellular protein metabolic processGO:00322682670.012
response to glucoseGO:00097491360.012
vasculature developmentGO:0001944700.012
regulation of protein maturationGO:1903317500.012
regulation of cyclic nucleotide biosynthetic processGO:0030802450.012
cyclic nucleotide biosynthetic processGO:0009190630.012
fructose 2 6 bisphosphate metabolic processGO:000600320.012
regulation of response to stressGO:00801341260.012
hemostasisGO:0007599260.012
positive regulation of organic acid transportGO:0032892220.012
purine ribonucleotide biosynthetic processGO:0009152810.012
synapse organizationGO:0050808460.012
regulation of body fluid levelsGO:0050878900.011
sex differentiationGO:00075481130.011
organ regenerationGO:00311001010.011
ensheathment of neuronsGO:0007272400.011
divalent inorganic cation transportGO:00725111340.011
carbohydrate derivative biosynthetic processGO:19011371240.011
cellular response to abiotic stimulusGO:0071214850.011
cell growthGO:00160491040.011
protein complex assemblyGO:00064612630.011
ribose phosphate biosynthetic processGO:0046390870.011
regulation of mapk cascadeGO:00434081160.011
negative regulation of ion transportGO:0043271510.011
mammary gland developmentGO:0030879380.011
regulation of interleukin 1 alpha productionGO:003265010.011
positive regulation of transmembrane transportGO:0034764250.011
sexual reproductionGO:00199531480.011
negative regulation of protein maturationGO:1903318470.011
cellular response to peptide hormone stimulusGO:00713751200.011
protein transportGO:00150311320.011
positive regulation of secretion by cellGO:19035321280.011
monovalent inorganic cation transportGO:00156721720.011
estrous cycle phaseGO:0060206150.011
protein homotetramerizationGO:0051289250.011
regulation of blood vessel sizeGO:0050880890.011
positive regulation of neuron deathGO:1901216430.011
interleukin 1 alpha productionGO:003261010.011
epithelial cell proliferationGO:0050673540.011
t cell costimulationGO:003129520.011
negative regulation of calcium ion importGO:009028120.011
negative regulation of neurogenesisGO:0050768780.011
tissue remodelingGO:0048771400.011
peptidyl amino acid modificationGO:00181931260.011
rho protein signal transductionGO:0007266110.011
maintenance of locationGO:0051235170.011
multicellular organismal water homeostasisGO:005089140.011
regulation of intracellular signal transductionGO:19025312180.010
hormone metabolic processGO:0042445690.010
cellular response to carbohydrate stimulusGO:0071322720.010
positive regulation of phosphorylationGO:00423271770.010
positive regulation of camp mediated signalingGO:004395020.010
monosaccharide metabolic processGO:0005996610.010
negative regulation of nervous system developmentGO:0051961790.010
positive regulation of ion transmembrane transportGO:0034767240.010
learning or memoryGO:0007611900.010
secretion by cellGO:00329402480.010
spermatogenesisGO:0007283990.010
rhythmic processGO:00485111560.010
positive regulation of secretionGO:00510471400.010
negative regulation of cell projection organizationGO:0031345500.010
glycosyl compound metabolic processGO:19016571820.010
nucleotide catabolic processGO:00091661390.010

Capn8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
urinary system diseaseDOID:1800.032
musculoskeletal system diseaseDOID:1700.028
disease of metabolismDOID:001466700.021
nervous system diseaseDOID:86300.020
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.012
inherited metabolic disorderDOID:65500.011