Rattus norvegicus

51 known processes

Dpyd

dihydropyrimidine dehydrogenase

Dpyd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.719
carboxylic acid metabolic processGO:00197522890.548
organic acid metabolic processGO:00060822920.371
fatty acid metabolic processGO:0006631990.228
monocarboxylic acid metabolic processGO:00327871520.217
agingGO:00075682410.187
cellular lipid metabolic processGO:00442552080.170
lipid metabolic processGO:00066292830.164
cellular hormone metabolic processGO:0034754490.164
cellular amino acid metabolic processGO:00065201070.159
response to extracellular stimulusGO:00099913800.144
response to corticosteroidGO:00319602350.138
response to nutrient levelsGO:00316673700.133
response to peptide hormoneGO:00434342780.131
response to glucocorticoidGO:00513842230.128
cellular response to organonitrogen compoundGO:00714171970.111
halogenated hydrocarbon metabolic processGO:004219740.108
gland developmentGO:00487321550.103
response to peptideGO:19016522920.102
organic acid biosynthetic processGO:0016053830.098
cellular response to peptideGO:19016531330.097
cellular ketone metabolic processGO:0042180510.096
organic substance catabolic processGO:19015753160.092
retinal metabolic processGO:004257430.091
organic hydroxy compound metabolic processGO:19016151150.090
catabolic processGO:00090563510.089
cellular response to peptide hormone stimulusGO:00713751200.089
small molecule biosynthetic processGO:00442831240.088
sulfur compound metabolic processGO:0006790700.085
liver developmentGO:0001889900.084
alpha amino acid metabolic processGO:1901605710.080
cellular response to oxygen containing compoundGO:19017013860.076
single organism catabolic processGO:00447122830.071
cellular response to endogenous stimulusGO:00714953770.071
response to acid chemicalGO:00011012220.071
response to insulinGO:00328681330.070
response to inorganic substanceGO:00100353770.069
response to xenobiotic stimulusGO:0009410230.067
hormone metabolic processGO:0042445690.064
oxidation reduction processGO:00551143040.063
steroid metabolic processGO:0008202730.063
small molecule catabolic processGO:0044282590.062
lipid biosynthetic processGO:00086101280.062
response to nutrientGO:00075842480.060
response to biotic stimulusGO:00096072260.060
response to metal ionGO:00100382530.058
intracellular signal transductionGO:00355563140.056
chlorinated hydrocarbon metabolic processGO:004219640.055
naphthalene metabolic processGO:001893120.055
response to ketoneGO:19016541820.054
cellular response to organic cyclic compoundGO:00714072020.053
single organism biosynthetic processGO:00447113420.049
hepaticobiliary system developmentGO:0061008900.048
unsaturated fatty acid metabolic processGO:0033559390.047
regulation of hormone levelsGO:00108171870.046
cellular response to xenobiotic stimulusGO:0071466190.046
response to external biotic stimulusGO:00432072210.046
cellular catabolic processGO:00442482950.046
calcitriol biosynthetic process from calciolGO:003637820.045
blood circulationGO:00080151830.045
phenol containing compound metabolic processGO:0018958300.044
regulation of cellular ketone metabolic processGO:0010565270.044
regulation of signal transductionGO:00099663180.042
cellular response to nitrogen compoundGO:19016992100.042
carbohydrate derivative metabolic processGO:19011353460.041
response to bacteriumGO:00096172000.041
naphthalene containing compound metabolic processGO:009042020.041
tube developmentGO:0035295890.040
response to growth factorGO:00708481890.038
icosanoid metabolic processGO:0006690380.038
reproductive processGO:00224143720.037
fatty acid derivative metabolic processGO:1901568380.037
multicellular organismal reproductive processGO:00486092330.037
central nervous system developmentGO:00074173110.036
response to carbohydrateGO:00097431830.036
cofactor metabolic processGO:0051186950.035
response to ethanolGO:00454711620.035
response to estrogenGO:00436272320.034
response to toxic substanceGO:00096361330.034
cellular response to lipidGO:00713962010.034
positive regulation of signalingGO:00230562700.034
regenerationGO:00310991630.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
response to amino acidGO:0043200750.033
cellular response to insulin stimulusGO:0032869810.033
response to reactive oxygen speciesGO:00003021200.033
regulation of molecular functionGO:00650093980.031
cellular response to growth factor stimulusGO:00713631620.031
cellular component biogenesisGO:00440853680.031
heterocycle catabolic processGO:00467001670.030
organic cyclic compound catabolic processGO:19013611750.030
neurological system processGO:00508772190.030
response to oxidative stressGO:00069791860.030
apoptotic processGO:00069153810.029
regulation of cellular amino acid metabolic processGO:000652120.029
aromatic compound catabolic processGO:00194391680.029
nucleoside metabolic processGO:00091161790.029
response to hypoxiaGO:00016662310.028
cellular response to external stimulusGO:00714961180.028
positive regulation of response to stimulusGO:00485842850.028
cellular amine metabolic processGO:0044106380.028
female pregnancyGO:00075651220.028
monocarboxylic acid transportGO:0015718520.027
anion transportGO:00068201780.027
response to vitaminGO:00332731310.027
organic acid catabolic processGO:0016054490.027
response to decreased oxygen levelsGO:00362932370.027
organic hydroxy compound biosynthetic processGO:1901617510.026
coenzyme metabolic processGO:0006732860.026
terpenoid metabolic processGO:0006721370.026
carboxylic acid catabolic processGO:0046395490.026
response to other organismGO:00517072200.026
tissue developmentGO:00098882520.026
positive regulation of cellular amine metabolic processGO:003324030.026
ribonucleoside metabolic processGO:00091191740.025
response to lipopolysaccharideGO:00324961910.025
organonitrogen compound biosynthetic processGO:19015661670.025
purine ribonucleoside metabolic processGO:00461281680.025
positive regulation of cellular amino acid metabolic processGO:004576410.025
nucleobase containing small molecule metabolic processGO:00550863160.025
organic acid transportGO:00158491160.025
organonitrogen compound catabolic processGO:19015651790.025
circulatory system processGO:00030131830.024
cellular response to extracellular stimulusGO:0031668730.024
reproductive structure developmentGO:00486081280.024
regulation of cellular amine metabolic processGO:003323880.024
response to monosaccharideGO:00342841590.024
cellular nitrogen compound catabolic processGO:00442701630.024
cellular response to stressGO:00335542690.024
triglyceride metabolic processGO:0006641210.024
response to molecule of bacterial originGO:00022371940.024
alkaloid metabolic processGO:000982030.023
multicellular organism reproductionGO:00325042330.023
behaviorGO:00076102050.023
glycosyl compound metabolic processGO:19016571820.023
protein transportGO:00150311320.023
regulation of intracellular signal transductionGO:19025312180.023
regulation of multicellular organismal developmentGO:20000263760.023
eye morphogenesisGO:004859240.023
positive regulation of signal transductionGO:00099671750.023
linoleic acid metabolic processGO:004365140.023
response to cytokineGO:00340972150.022
positive regulation of catalytic activityGO:00430851840.022
cellular chemical homeostasisGO:00550822470.022
isoprenoid metabolic processGO:0006720450.022
purine nucleoside metabolic processGO:00422781690.022
glial cell differentiationGO:0010001650.022
multi organism reproductive processGO:00447032620.022
single organism reproductive processGO:00447022970.022
cellular modified amino acid metabolic processGO:0006575610.022
regulation of cell differentiationGO:00455953200.022
macromolecule localizationGO:00330362520.022
reproductionGO:00000032450.022
response to cadmium ionGO:0046686350.022
chemical homeostasisGO:00488782920.021
protein complex biogenesisGO:00702712630.021
purine containing compound metabolic processGO:00725212530.021
regulation of phosphate metabolic processGO:00192203490.021
acylglycerol metabolic processGO:0006639210.021
response to organophosphorusGO:00466831020.021
positive regulation of cell proliferationGO:00082842490.021
alcohol metabolic processGO:0006066770.020
chromosome segregationGO:000705920.020
single organism carbohydrate metabolic processGO:00447231180.020
cellular response to reactive oxygen speciesGO:0034614550.020
reproductive system developmentGO:00614581280.020
negative regulation of cell deathGO:00605482290.020
defense responseGO:00069521940.020
long chain fatty acid metabolic processGO:0001676320.020
negative regulation of metabolic processGO:00098923310.020
neuron developmentGO:00486662860.020
cellular response to hormone stimulusGO:00328702470.020
head developmentGO:00603222470.020
positive regulation of intracellular signal transductionGO:19025331380.020
regulation of phosphorylationGO:00423252480.020
transmembrane transportGO:00550854120.020
positive regulation of protein metabolic processGO:00512471780.020
carbohydrate metabolic processGO:00059751300.020
cellular response to steroid hormone stimulusGO:0071383930.020
organophosphate metabolic processGO:00196373700.020
cellular amino acid biosynthetic processGO:0008652320.020
diterpenoid metabolic processGO:0016101330.019
exogenous drug catabolic processGO:004273810.019
macromolecular complex subunit organizationGO:00439333390.019
ras protein signal transductionGO:0007265290.019
regulation of secretion by cellGO:19035302080.019
brain developmentGO:00074202470.019
positive regulation of phosphorus metabolic processGO:00105622620.019
response to purine containing compoundGO:00140741260.019
ion transmembrane transportGO:00342203650.019
positive regulation of cellular protein metabolic processGO:00322701670.018
inner medullary collecting duct developmentGO:007206110.018
monosaccharide metabolic processGO:0005996610.018
positive regulation of developmental processGO:00510942830.018
regulation of catabolic processGO:00098941130.018
alditol metabolic processGO:001940040.018
catechol containing compound metabolic processGO:0009712190.018
cellular component assemblyGO:00226073600.018
action potentialGO:0001508540.018
response to oxygen levelsGO:00704822650.018
positive regulation of protein phosphorylationGO:00019341350.018
neutral lipid metabolic processGO:0006638210.018
regulation of catalytic activityGO:00507903040.018
neuron differentiationGO:00301823680.018
regulation of mapk cascadeGO:00434081160.018
positive regulation of phosphate metabolic processGO:00459372620.018
positive regulation of phosphorylationGO:00423271770.018
protein localizationGO:00081041910.017
regulation of nervous system developmentGO:00519602640.017
neuron projection developmentGO:00311752730.017
regulation of membrane potentialGO:00423911100.017
nicotine metabolic processGO:001893310.017
amine metabolic processGO:0009308380.017
cellular response to alcoholGO:0097306870.017
macromolecular complex assemblyGO:00650032730.017
organelle organizationGO:00069962660.017
cellular amino acid catabolic processGO:0009063210.017
glycerolipid metabolic processGO:0046486670.017
monocarboxylic acid biosynthetic processGO:0072330480.017
positive regulation of cell developmentGO:00107201760.017
developmental process involved in reproductionGO:00030061590.017
cellular ion homeostasisGO:00068731840.017
transmission of nerve impulseGO:0019226420.017
protein oligomerizationGO:00512591910.017
positive regulation of multicellular organismal processGO:00512403870.017
response to testosteroneGO:0033574550.017
small gtpase mediated signal transductionGO:0007264360.017
lipid catabolic processGO:0016042460.017
neuronal action potentialGO:0019228350.016
arachidonic acid metabolic processGO:0019369200.016
regulation of phosphorus metabolic processGO:00511743490.016
nucleoside phosphate metabolic processGO:00067532830.016
programmed cell deathGO:00125013920.016
neuron projection morphogenesisGO:00488121220.016
ion homeostasisGO:00508012120.016
cellular response to ketoneGO:1901655510.016
regulation of programmed cell deathGO:00430673410.016
cellular response to corticosteroid stimulusGO:0071384690.016
locomotionGO:00400112370.016
negative regulation of cellular metabolic processGO:00313242810.016
positive regulation of transportGO:00510502450.016
anatomical structure morphogenesisGO:00096532980.015
gliogenesisGO:0042063930.015
positive regulation of cell differentiationGO:00455972170.015
lipid storageGO:001991510.015
protein complex assemblyGO:00064612630.015
transcription dna templatedGO:00063513770.015
regulation of rna biosynthetic processGO:20011413810.015
protein phosphorylationGO:00064683450.015
positive regulation of cell motilityGO:2000147970.015
regulation of neurogenesisGO:00507672470.015
homeostatic processGO:00425923310.015
negative regulation of programmed cell deathGO:00430691830.015
regulation of nucleic acid templated transcriptionGO:19035063800.015
retinoid metabolic processGO:0001523240.015
forebrain developmentGO:0030900980.015
response to insecticideGO:0017085210.015
single organism cellular localizationGO:19025801020.015
response to hexoseGO:00097461440.015
4 chlorobiphenyl metabolic processGO:001888010.015
vitamin d3 metabolic processGO:007064020.015
purine ribonucleotide metabolic processGO:00091502270.015
alpha amino acid catabolic processGO:1901606200.015
carboxylic acid transportGO:00469421150.014
heart morphogenesisGO:000300730.014
xenobiotic metabolic processGO:0006805190.014
4 nitrophenol metabolic processGO:001896010.014
positive regulation of cellular biosynthetic processGO:00313282950.014
peptidyl tyrosine modificationGO:0018212720.014
organophosphate catabolic processGO:00464341480.014
axis specificationGO:000979840.014
fat soluble vitamin biosynthetic processGO:004236220.014
cellular component movementGO:00069282480.014
cytoplasmic transportGO:00164821150.014
cellular homeostasisGO:00197252520.014
regulation of transcription dna templatedGO:00063553740.014
response to hydrogen peroxideGO:0042542890.014
peptidyl amino acid modificationGO:00181931260.014
regulation of cell developmentGO:00602842630.014
cell cell signalingGO:00072673350.014
nucleic acid templated transcriptionGO:00976593790.014
protein homooligomerizationGO:0051260910.014
intracellular transportGO:00469071850.014
response to starvationGO:0042594590.014
protein complex subunit organizationGO:00718223020.014
positive regulation of nervous system developmentGO:00519621780.014
positive regulation of neurogenesisGO:00507691650.014
positive regulation of molecular functionGO:00440932300.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
c21 steroid hormone metabolic processGO:0008207140.014
steroid biosynthetic processGO:0006694480.014
secretionGO:00469033070.013
cellular macromolecule localizationGO:00707271220.013
regulation of proteasomal protein catabolic processGO:006113640.013
purine nucleotide metabolic processGO:00061632290.013
rna biosynthetic processGO:00327743800.013
response to temperature stimulusGO:0009266940.013
mesoderm developmentGO:000749820.013
maintenance of locationGO:0051235170.013
organ regenerationGO:00311001010.013
regulation of cellular protein metabolic processGO:00322682670.013
growthGO:00400071650.013
positive regulation of gene expressionGO:00106282440.013
carboxylic acid biosynthetic processGO:0046394830.013
regulation of system processGO:00440572080.013
ribonucleotide metabolic processGO:00092592310.013
kidney developmentGO:0001822670.013
response to estradiolGO:00323551640.013
positive regulation of biosynthetic processGO:00098913190.013
cell part morphogenesisGO:00329901230.013
regulation of transferase activityGO:00513381230.013
response to sulfur dioxideGO:001047730.013
cell projection organizationGO:00300303020.013
fatty acid catabolic processGO:0009062260.013
regulation of anatomical structure sizeGO:00900661350.013
protein localization to organelleGO:0033365570.013
drug metabolic processGO:0017144110.013
regulation of protein metabolic processGO:00512462890.013
epoxygenase p450 pathwayGO:001937310.013
salivary gland developmentGO:000743130.012
cellular alcohol biosynthetic processGO:004410820.012
regulation of lipid metabolic processGO:0019216680.012
positive regulation of protein modification processGO:00314011420.012
positive regulation of cellular component organizationGO:00511302000.012
cellular protein localizationGO:00346131220.012
hormone biosynthetic processGO:0042446250.012
immune system processGO:00023762040.012
secretion by cellGO:00329402480.012
negative regulation of protein import into nucleus translocationGO:003315910.012
regulation of protein modification processGO:00313991940.012
neuron apoptotic processGO:0051402880.012
cell type specific apoptotic processGO:00972851340.012
regulation of protein phosphorylationGO:00019321830.012
sulfur amino acid metabolic processGO:000009690.012
cellular component morphogenesisGO:00329891550.012
cation transportGO:00068123820.012
ribose phosphate metabolic processGO:00196932350.012
positive regulation of cell communicationGO:00106472710.012
sex differentiationGO:00075481130.012
chemosensory behaviorGO:000763520.012
drug catabolic processGO:004273710.012
epithelium developmentGO:0060429960.012
regulation of cell proliferationGO:00421273590.012
response to alkaloidGO:00432791320.012
renal system developmentGO:0072001670.012
negative regulation of macromolecule metabolic processGO:00106052600.012
response to vitamin dGO:0033280340.012
cellular response to cytokine stimulusGO:00713451270.012
dicarboxylic acid metabolic processGO:0043648420.012
vitamin d metabolic processGO:004235940.012
cell morphogenesisGO:00009021420.012
membrane organizationGO:0061024940.012
organic anion transportGO:00157111320.011
vitamin d biosynthetic processGO:004236820.011
gastrulationGO:000736920.011
cellular response to metal ionGO:0071248550.011
nucleobase containing compound catabolic processGO:00346551520.011
positive regulation of catabolic processGO:0009896780.011
response to radiationGO:00093141370.011
gonad developmentGO:00084061040.011
thioester metabolic processGO:0035383280.011
androgen metabolic processGO:0008209140.011
cellular response to nutrient levelsGO:0031669600.011
response to transition metal nanoparticleGO:19902671220.011
xenobiotic catabolic processGO:004217870.011
cellular amide metabolic processGO:0043603440.011
lipid transportGO:0006869610.011
regulation of cellular component organizationGO:00511283680.011
negative regulation of apoptotic processGO:00430661810.011
nucleoside catabolic processGO:00091641260.011
negative regulation of cell communicationGO:00106481580.011
regulation of neuron differentiationGO:00456642080.011
single organism behaviorGO:00447081300.011
response to transforming growth factor betaGO:0071559460.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
alpha amino acid biosynthetic processGO:1901607230.011
regulation of cellular localizationGO:00603412630.011
regulation of tube sizeGO:0035150890.011
regulation of cell migrationGO:00303341280.011
cation homeostasisGO:00550801950.011
single organism organelle organizationGO:19025891800.011
regulation of cell projection organizationGO:00313441750.011
rna metabolic processGO:00160704060.011
sulfationGO:005192320.011
regulation of blood pressureGO:0008217830.011
olfactory behaviorGO:004204820.011
aromatic amino acid family catabolic processGO:000907470.011
regulation of cellular catabolic processGO:00313291010.010
negative regulation of cell cycle phase transitionGO:190198840.010
reactive oxygen species metabolic processGO:0072593370.010
ribonucleoside catabolic processGO:00424541260.010
regulation of neuron deathGO:19012141150.010
response to woundingGO:00096112540.010
lauric acid metabolic processGO:004825240.010
positive regulation of neuron differentiationGO:00456661260.010
phthalate metabolic processGO:001896380.010
defense response to gram negative bacteriumGO:005082930.010
serine family amino acid metabolic processGO:0009069120.010
positive regulation of transcription dna templatedGO:00458931970.010
benzene containing compound metabolic processGO:0042537220.010
oligopeptide transportGO:000685740.010
regulation of cellular component movementGO:00512701500.010
gtp catabolic processGO:0006184710.010
negative regulation of macromolecule biosynthetic processGO:00105581480.010
single organism intracellular transportGO:19025821660.010
cellular lipid catabolic processGO:0044242370.010

Dpyd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.054
inherited metabolic disorderDOID:65500.054
disease of anatomical entityDOID:700.026
vascular diseaseDOID:17800.026
cardiovascular system diseaseDOID:128700.026
hypertensionDOID:1076300.018
artery diseaseDOID:005082800.018
nervous system diseaseDOID:86300.016
disease of cellular proliferationDOID:1456600.011