IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Etfdh

electron-transferring-flavoprotein dehydrogenase

(Aliases: MGC93785)

Ensembl: ENSRNOG00000009538
RGD: 735052
Entrez: 295143
UniProtKB: Q66HF3

Process Predictions
Disease Predictions

Etfdh biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
lipid oxidation	GO:0034440	30	1.000
fatty acid oxidation	GO:0019395	29	1.000
monocarboxylic acid catabolic process	GO:0072329	28	0.999
fatty acid beta oxidation	GO:0006635	22	0.997
fatty acid catabolic process	GO:0009062	26	0.997
cellular lipid catabolic process	GO:0044242	37	0.987
fatty acid metabolic process	GO:0006631	99	0.986
small molecule catabolic process	GO:0044282	59	0.979
monocarboxylic acid metabolic process	GO:0032787	152	0.958
carboxylic acid catabolic process	GO:0046395	49	0.951
cellular lipid metabolic process	GO:0044255	208	0.944
lipid modification	GO:0030258	52	0.944
carboxylic acid metabolic process	GO:0019752	289	0.942
oxidation reduction process	GO:0055114	304	0.905
oxoacid metabolic process	GO:0043436	290	0.891
lipid catabolic process	GO:0016042	46	0.886
carnitine metabolic process	GO:0009437	3	0.797
organic acid metabolic process	GO:0006082	292	0.707
organic acid catabolic process	GO:0016054	49	0.633
long chain fatty acid metabolic process	GO:0001676	32	0.626
lipid metabolic process	GO:0006629	283	0.594
single organism catabolic process	GO:0044712	283	0.436
glycogen biosynthetic process	GO:0005978	15	0.413
cellular ketone metabolic process	GO:0042180	51	0.390
single organism biosynthetic process	GO:0044711	342	0.376
cellular catabolic process	GO:0044248	295	0.351
regulation of gluconeogenesis	GO:0006111	4	0.317
regulation of fatty acid oxidation	GO:0046320	10	0.314
generation of precursor metabolites and energy	GO:0006091	62	0.285
glucan metabolic process	GO:0044042	23	0.270
cellular glucan metabolic process	GO:0006073	23	0.262
response to nutrient levels	GO:0031667	370	0.260
lipid biosynthetic process	GO:0008610	128	0.249
organic substance catabolic process	GO:1901575	316	0.247
regulation of cellular ketone metabolic process	GO:0010565	27	0.240
gland development	GO:0048732	155	0.236
positive regulation of triglyceride biosynthetic process	GO:0010867	4	0.208
energy reserve metabolic process	GO:0006112	25	0.204
fatty acid beta oxidation using acyl coa dehydrogenase	GO:0033539	4	0.196
protein homotetramerization	GO:0051289	25	0.192
energy derivation by oxidation of organic compounds	GO:0015980	46	0.190
hexose metabolic process	GO:0019318	58	0.187
androgen metabolic process	GO:0008209	14	0.185
regulation of fatty acid beta oxidation	GO:0031998	8	0.179
regulation of fatty acid metabolic process	GO:0019217	18	0.167
response to extracellular stimulus	GO:0009991	380	0.161
regulation of lipid metabolic process	GO:0019216	68	0.160
acetyl coa metabolic process	GO:0006084	17	0.155
catabolic process	GO:0009056	351	0.155
cellular component assembly	GO:0022607	360	0.152
protein homooligomerization	GO:0051260	91	0.149
amino acid betaine metabolic process	GO:0006577	3	0.146
tissue development	GO:0009888	252	0.141
carboxylic acid biosynthetic process	GO:0046394	83	0.140
steroid metabolic process	GO:0008202	73	0.140
long chain fatty acid import	GO:0044539	1	0.139
fatty acid biosynthetic process	GO:0006633	33	0.132
acetate ester biosynthetic process	GO:1900620	2	0.129
lipid localization	GO:0010876	62	0.128
acyl coa metabolic process	GO:0006637	28	0.125
long chain fatty acid transport	GO:0015909	14	0.113
negative regulation of fatty acid oxidation	GO:0046322	2	0.106
single organism carbohydrate metabolic process	GO:0044723	118	0.104
protein tetramerization	GO:0051262	38	0.100
neurotransmitter biosynthetic process	GO:0042136	2	0.097
response to acid chemical	GO:0001101	222	0.095
very long chain fatty acid catabolic process	GO:0042760	2	0.090
cellular component biogenesis	GO:0044085	368	0.084
sulfur compound metabolic process	GO:0006790	70	0.083
response to nutrient	GO:0007584	248	0.082
protein oligomerization	GO:0051259	191	0.082
regulation of cholesterol metabolic process	GO:0090181	5	0.078
small molecule biosynthetic process	GO:0044283	124	0.076
macromolecular complex assembly	GO:0065003	273	0.066
cellular response to oxygen containing compound	GO:1901701	386	0.066
fatty acid transmembrane transport	GO:1902001	3	0.065
glucan biosynthetic process	GO:0009250	15	0.065
organic anion transport	GO:0015711	132	0.065
valine metabolic process	GO:0006573	1	0.063
organophosphate metabolic process	GO:0019637	370	0.061
temperature homeostasis	GO:0001659	17	0.060
negative regulation of cellular biosynthetic process	GO:0031327	161	0.056
cellular polysaccharide metabolic process	GO:0044264	23	0.056
protein complex subunit organization	GO:0071822	302	0.054
response to carbohydrate	GO:0009743	183	0.053
protein complex biogenesis	GO:0070271	263	0.053
protein complex assembly	GO:0006461	263	0.051
fatty acid derivative metabolic process	GO:1901568	38	0.050
cellular polysaccharide biosynthetic process	GO:0033692	15	0.050
glycosyl compound metabolic process	GO:1901657	182	0.049
nucleobase containing small molecule metabolic process	GO:0055086	316	0.049
positive regulation of fatty acid oxidation	GO:0046321	6	0.048
fatty acid transport	GO:0015908	25	0.046
programmed cell death	GO:0012501	392	0.046
polysaccharide biosynthetic process	GO:0000271	16	0.046
monocarboxylic acid biosynthetic process	GO:0072330	48	0.046
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.045
response to estradiol	GO:0032355	164	0.044
response to monosaccharide	GO:0034284	159	0.044
response to oxygen levels	GO:0070482	265	0.043
regulation of lipid biosynthetic process	GO:0046890	38	0.043
carbohydrate derivative metabolic process	GO:1901135	346	0.043
monosaccharide metabolic process	GO:0005996	61	0.042
very long chain fatty acid metabolic process	GO:0000038	3	0.042
organic hydroxy compound metabolic process	GO:1901615	115	0.042
carbohydrate biosynthetic process	GO:0016051	42	0.041
regulation of cellular localization	GO:0060341	263	0.041
response to estrogen	GO:0043627	232	0.040
branched chain amino acid metabolic process	GO:0009081	4	0.040
macromolecular complex subunit organization	GO:0043933	339	0.040
response to peptide hormone	GO:0043434	278	0.040
glucose metabolic process	GO:0006006	52	0.039
urogenital system development	GO:0001655	78	0.039
glycerolipid metabolic process	GO:0046486	67	0.039
gluconeogenesis	GO:0006094	15	0.039
purine containing compound metabolic process	GO:0072521	253	0.038
homeostatic process	GO:0042592	331	0.037
negative regulation of metabolic process	GO:0009892	331	0.036
liver development	GO:0001889	90	0.036
thioester metabolic process	GO:0035383	28	0.036
secretion by cell	GO:0032940	248	0.036
regulation of hormone levels	GO:0010817	187	0.036
cofactor metabolic process	GO:0051186	95	0.035
regulation of protein metabolic process	GO:0051246	289	0.035
heart development	GO:0007507	72	0.035
response to peptide	GO:1901652	292	0.034
purine ribonucleotide metabolic process	GO:0009150	227	0.033
regulation of triglyceride biosynthetic process	GO:0010866	4	0.033
ribonucleoside metabolic process	GO:0009119	174	0.032
signal release	GO:0023061	145	0.032
acylglycerol metabolic process	GO:0006639	21	0.031
antral ovarian follicle growth	GO:0001547	3	0.031
unsaturated fatty acid metabolic process	GO:0033559	39	0.031
response to inorganic substance	GO:0010035	377	0.031
negative regulation of lipid biosynthetic process	GO:0051055	2	0.031
branched chain amino acid catabolic process	GO:0009083	4	0.031
positive regulation of lipid catabolic process	GO:0050996	4	0.030
hepaticobiliary system development	GO:0061008	90	0.030
organic hydroxy compound biosynthetic process	GO:1901617	51	0.030
positive regulation of phosphorylation	GO:0042327	177	0.030
ribose phosphate metabolic process	GO:0019693	235	0.030
developmental process involved in reproduction	GO:0003006	159	0.030
reactive oxygen species metabolic process	GO:0072593	37	0.029
regulation of secretion by cell	GO:1903530	208	0.029
purine nucleotide metabolic process	GO:0006163	229	0.029
kidney development	GO:0001822	67	0.029
cellular response to nitrogen compound	GO:1901699	210	0.028
regulation of protein modification process	GO:0031399	194	0.028
negative regulation of cellular metabolic process	GO:0031324	281	0.028
response to cold	GO:0009409	29	0.028
regulation of secretion	GO:0051046	224	0.028
cellular response to endogenous stimulus	GO:0071495	377	0.027
tricarboxylic acid cycle	GO:0006099	11	0.027
cellular response to organic cyclic compound	GO:0071407	202	0.026
carbohydrate metabolic process	GO:0005975	130	0.026
aging	GO:0007568	241	0.026
regulation of peptide secretion	GO:0002791	82	0.026
positive regulation of molecular function	GO:0044093	230	0.025
positive regulation of fatty acid beta oxidation	GO:0032000	4	0.025
positive regulation of triglyceride metabolic process	GO:0090208	4	0.025
cell projection organization	GO:0030030	302	0.025
organic acid transport	GO:0015849	116	0.025
peptide secretion	GO:0002790	86	0.025
nucleoside metabolic process	GO:0009116	179	0.025
cellular amine metabolic process	GO:0044106	38	0.024
regulation of phosphorus metabolic process	GO:0051174	349	0.024
hormone mediated signaling pathway	GO:0009755	23	0.024
nucleoside phosphate metabolic process	GO:0006753	283	0.023
neutral lipid metabolic process	GO:0006638	21	0.023
atp synthesis coupled electron transport	GO:0042773	2	0.023
organelle organization	GO:0006996	266	0.023
hormone biosynthetic process	GO:0042446	25	0.023
regulation of peptide transport	GO:0090087	87	0.022
regulation of cellular protein metabolic process	GO:0032268	267	0.022
regulation of catabolic process	GO:0009894	113	0.022
positive regulation of protein metabolic process	GO:0051247	178	0.022
aerobic respiration	GO:0009060	13	0.022
purine nucleoside metabolic process	GO:0042278	169	0.021
response to starvation	GO:0042594	59	0.021
cellular response to peptide	GO:1901653	133	0.020
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.020
growth	GO:0040007	165	0.020
positive regulation of phosphorus metabolic process	GO:0010562	262	0.019
cellular response to insulin stimulus	GO:0032869	81	0.019
positive regulation of fatty acid transport	GO:2000193	9	0.019
response to decreased oxygen levels	GO:0036293	237	0.019
amine metabolic process	GO:0009308	38	0.019
regulation of cellular catabolic process	GO:0031329	101	0.019
regulation of body fluid levels	GO:0050878	90	0.019
cellular nitrogen compound catabolic process	GO:0044270	163	0.018
positive regulation of biosynthetic process	GO:0009891	319	0.018
cellular response to hormone stimulus	GO:0032870	247	0.018
female pregnancy	GO:0007565	122	0.018
cellular response to lipid	GO:0071396	201	0.018
positive regulation of phosphate metabolic process	GO:0045937	262	0.018
regulation of peptide hormone secretion	GO:0090276	80	0.018
negative regulation of biosynthetic process	GO:0009890	168	0.017
ribonucleotide metabolic process	GO:0009259	231	0.017
regulation of hormone secretion	GO:0046883	106	0.017
regulation of phosphate metabolic process	GO:0019220	349	0.017
response to growth factor	GO:0070848	189	0.017
positive regulation of protein phosphorylation	GO:0001934	135	0.017
pyrimidine nucleobase catabolic process	GO:0006208	3	0.017
positive regulation of cellular amine metabolic process	GO:0033240	3	0.017
regulation of protein phosphorylation	GO:0001932	183	0.016
regulation of cell differentiation	GO:0045595	320	0.016
response to corticosteroid	GO:0031960	235	0.016
multicellular organism reproduction	GO:0032504	233	0.016
apoptotic mitochondrial changes	GO:0008637	10	0.016
regulation of blood vessel size	GO:0050880	89	0.016
dicarboxylic acid metabolic process	GO:0043648	42	0.016
response to hexose	GO:0009746	144	0.016
regulation of steroid metabolic process	GO:0019218	25	0.015
coenzyme metabolic process	GO:0006732	86	0.015
response to glucocorticoid	GO:0051384	223	0.015
regulation of programmed cell death	GO:0043067	341	0.015
negative regulation of programmed cell death	GO:0043069	183	0.015
cellular response to peptide hormone stimulus	GO:0071375	120	0.015
regulation of phosphorylation	GO:0042325	248	0.015
regulation of cellular amino acid metabolic process	GO:0006521	2	0.015
ovulation cycle process	GO:0022602	50	0.015
insulin secretion	GO:0030073	69	0.015
regulation of catalytic activity	GO:0050790	304	0.015
neurological system process	GO:0050877	219	0.015
regulation of intracellular transport	GO:0032386	65	0.014
peptide transport	GO:0015833	97	0.014
metanephric tubule development	GO:0072170	4	0.014
positive regulation of cellular protein metabolic process	GO:0032270	167	0.014
hormone transport	GO:0009914	121	0.014
cellular response to organonitrogen compound	GO:0071417	197	0.014
negative regulation of cell death	GO:0060548	229	0.014
positive regulation of blood circulation	GO:1903524	65	0.014
cellular response to reactive oxygen species	GO:0034614	55	0.014
negative regulation of macromolecule metabolic process	GO:0010605	260	0.014
purine ribonucleoside metabolic process	GO:0046128	168	0.014
regulation of cellular carbohydrate metabolic process	GO:0010675	39	0.014
striated muscle tissue development	GO:0014706	58	0.013
regulation of blood pressure	GO:0008217	83	0.013
single organism organelle organization	GO:1902589	180	0.013
cell morphogenesis	GO:0000902	142	0.013
regulation of insulin secretion	GO:0050796	65	0.013
regulation of kinase activity	GO:0043549	117	0.013
positive regulation of jak stat cascade	GO:0046427	19	0.013
positive regulation of multicellular organismal process	GO:0051240	387	0.013
positive regulation of fatty acid metabolic process	GO:0045923	14	0.013
response to metal ion	GO:0010038	253	0.013
muscle structure development	GO:0061061	87	0.013
icosanoid metabolic process	GO:0006690	38	0.013
response to wounding	GO:0009611	254	0.013
positive regulation of signal transduction	GO:0009967	175	0.013
fatty acyl coa metabolic process	GO:0035337	1	0.013
response to toxic substance	GO:0009636	133	0.013
amide transport	GO:0042886	105	0.012
negative regulation of transport	GO:0051051	136	0.012
positive regulation of catalytic activity	GO:0043085	184	0.012
renal system development	GO:0072001	67	0.012
medium chain fatty acid metabolic process	GO:0051791	5	0.012
peptide hormone secretion	GO:0030072	84	0.012
neutral lipid biosynthetic process	GO:0046460	7	0.012
cellular response to oxidative stress	GO:0034599	76	0.012
cellular response to cytokine stimulus	GO:0071345	127	0.012
response to glucose	GO:0009749	136	0.012
metanephric epithelium development	GO:0072207	4	0.012
response to transition metal nanoparticle	GO:1990267	122	0.012
nucleotide metabolic process	GO:0009117	279	0.012
cellular hormone metabolic process	GO:0034754	49	0.012
regulation of tube size	GO:0035150	89	0.012
regulation of molecular function	GO:0065009	398	0.012
hormone metabolic process	GO:0042445	69	0.011
triglyceride metabolic process	GO:0006641	21	0.011
positive regulation of cell differentiation	GO:0045597	217	0.011
response to bacterium	GO:0009617	200	0.011
response to food	GO:0032094	27	0.011
cellular respiration	GO:0045333	21	0.011
central nervous system development	GO:0007417	311	0.011
anion transport	GO:0006820	178	0.011
acylglycerol biosynthetic process	GO:0046463	7	0.011
positive regulation of intracellular signal transduction	GO:1902533	138	0.011
response to hypoxia	GO:0001666	231	0.011
reproductive system development	GO:0061458	128	0.011
response to external biotic stimulus	GO:0043207	221	0.011
cellular carbohydrate metabolic process	GO:0044262	72	0.011
hexose biosynthetic process	GO:0019319	15	0.010
positive regulation of protein modification process	GO:0031401	142	0.010
protein phosphorylation	GO:0006468	345	0.010
acetyl coa biosynthetic process from pyruvate	GO:0006086	5	0.010
ion transmembrane transport	GO:0034220	365	0.010
secretion	GO:0046903	307	0.010
progesterone metabolic process	GO:0042448	8	0.010
lipid transport	GO:0006869	61	0.010
brain development	GO:0007420	247	0.010

Etfdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
inherited metabolic disorder	DOID:655	0.321
disease of metabolism	DOID:0014667	0.321
nervous system disease	DOID:863	0.018
disease of anatomical entity	DOID:7	0.018
sensory system disease	DOID:0050155	0.017
eye and adnexa disease	DOID:1492	0.017
eye disease	DOID:5614	0.017
retinal disease	DOID:5679	0.017
gastrointestinal system disease	DOID:77	0.012

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