Rattus norvegicus

46 known processes

Pfkm

phosphofructokinase, muscle

(Aliases: Pfk-M,PFK-A)

Pfkm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
generation of precursor metabolites and energyGO:0006091620.961
oxoacid metabolic processGO:00434362900.596
carboxylic acid metabolic processGO:00197522890.588
single organism carbohydrate metabolic processGO:00447231180.499
energy derivation by oxidation of organic compoundsGO:0015980460.487
purine ribonucleoside monophosphate metabolic processGO:0009167840.465
organophosphate metabolic processGO:00196373700.419
ribose phosphate biosynthetic processGO:0046390870.374
carbohydrate metabolic processGO:00059751300.326
oxidation reduction processGO:00551143040.325
organic substance catabolic processGO:19015753160.269
organic acid metabolic processGO:00060822920.251
single organism carbohydrate catabolic processGO:0044724400.249
organophosphate biosynthetic processGO:00904071430.249
monocarboxylic acid metabolic processGO:00327871520.240
single organism biosynthetic processGO:00447113420.235
glycogen metabolic processGO:0005977230.226
carbohydrate catabolic processGO:0016052400.189
carboxylic acid biosynthetic processGO:0046394830.185
organic acid biosynthetic processGO:0016053830.167
pyruvate metabolic processGO:0006090270.159
glucan metabolic processGO:0044042230.145
carbohydrate derivative metabolic processGO:19011353460.141
nucleobase containing small molecule metabolic processGO:00550863160.137
regulation of molecular functionGO:00650093980.136
nucleotide metabolic processGO:00091172790.129
nucleoside monophosphate metabolic processGO:0009123930.126
nucleoside phosphate metabolic processGO:00067532830.122
neurological system processGO:00508772190.121
ribose phosphate metabolic processGO:00196932350.121
glycosyl compound catabolic processGO:19016581260.118
response to monosaccharideGO:00342841590.115
single organism catabolic processGO:00447122830.114
regulation of ion transportGO:00432692450.106
ribonucleoside metabolic processGO:00091191740.105
oxaloacetate metabolic processGO:000610760.104
regulation of phosphate metabolic processGO:00192203490.103
cellular component biogenesisGO:00440853680.102
glucose metabolic processGO:0006006520.099
cellular carbohydrate metabolic processGO:0044262720.095
cellular glucan metabolic processGO:0006073230.095
divalent metal ion transportGO:00708381320.095
hexose metabolic processGO:0019318580.090
cellular calcium ion homeostasisGO:00068741600.087
glycosyl compound metabolic processGO:19016571820.086
positive regulation of transportGO:00510502450.085
cellular polysaccharide metabolic processGO:0044264230.085
ribonucleoside monophosphate metabolic processGO:0009161880.084
nucleotide catabolic processGO:00091661390.083
acetyl coa metabolic processGO:0006084170.082
regulation of cell maturationGO:190342930.082
cellular chemical homeostasisGO:00550822470.082
calcium ion transportGO:00068161310.082
cation homeostasisGO:00550801950.081
response to peptide hormoneGO:00434342780.080
nucleoside metabolic processGO:00091161790.079
fatty acid metabolic processGO:0006631990.079
chemical homeostasisGO:00488782920.079
positive regulation of cell developmentGO:00107201760.078
regulation of phosphorus metabolic processGO:00511743490.075
purine nucleotide biosynthetic processGO:0006164830.073
purine ribonucleoside metabolic processGO:00461281680.073
cellular homeostasisGO:00197252520.070
Human
cation transportGO:00068123820.069
apoptotic processGO:00069153810.067
response to organophosphorusGO:00466831020.067
regulation of rna biosynthetic processGO:20011413810.066
positive regulation of multicellular organismal processGO:00512403870.066
amp metabolic processGO:004603380.064
ribonucleotide biosynthetic processGO:0009260850.064
ribonucleotide metabolic processGO:00092592310.062
polysaccharide metabolic processGO:0005976250.062
negative regulation of metabolic processGO:00098923310.062
nucleoside monophosphate biosynthetic processGO:0009124280.062
respiratory gaseous exchangeGO:000758540.060
neuron differentiationGO:00301823680.059
cellular response to hormone stimulusGO:00328702470.059
acyl coa metabolic processGO:0006637280.058
purine containing compound biosynthetic processGO:0072522850.058
purine nucleoside monophosphate metabolic processGO:0009126840.056
regulation of rna metabolic processGO:00512523910.055
ion homeostasisGO:00508012120.055
intracellular signal transductionGO:00355563140.055
synapse organizationGO:0050808460.054
energy reserve metabolic processGO:0006112250.053
monosaccharide metabolic processGO:0005996610.053
cellular catabolic processGO:00442482950.052
anatomical structure morphogenesisGO:00096532980.052
homeostatic processGO:00425923310.052
Human
positive regulation of biosynthetic processGO:00098913190.052
rna biosynthetic processGO:00327743800.051
metal ion transportGO:00300012890.050
purine nucleoside metabolic processGO:00422781690.050
cellular divalent inorganic cation homeostasisGO:00725031620.050
positive regulation of phosphate metabolic processGO:00459372620.050
cation transmembrane transportGO:00986552630.050
positive regulation of phosphorus metabolic processGO:00105622620.050
purine nucleoside triphosphate catabolic processGO:00091461220.049
protein phosphorylationGO:00064683450.049
neuron projection morphogenesisGO:00488121220.049
cellular component assemblyGO:00226073600.049
nucleoside diphosphate metabolic processGO:0009132140.049
metal ion homeostasisGO:00550651860.048
alpha amino acid catabolic processGO:1901606200.047
response to ketoneGO:19016541820.047
purine ribonucleoside biosynthetic processGO:0046129210.047
cell projection morphogenesisGO:00488581230.047
divalent inorganic cation transportGO:00725111340.047
regulation of metal ion transportGO:00109591180.047
aromatic compound catabolic processGO:00194391680.046
response to hexoseGO:00097461440.046
lipid biosynthetic processGO:00086101280.046
cofactor metabolic processGO:0051186950.045
negative regulation of macromolecule metabolic processGO:00106052600.044
regulation of nucleotide metabolic processGO:00061401170.044
calcium ion homeostasisGO:00550741620.043
programmed cell deathGO:00125013920.043
purine containing compound metabolic processGO:00725212530.043
nucleic acid templated transcriptionGO:00976593790.043
regulation of nucleic acid templated transcriptionGO:19035063800.042
growthGO:00400071650.041
regulation of calcium ion transportGO:0051924770.041
cellular ketone metabolic processGO:0042180510.040
cell projection organizationGO:00300303020.039
gtp metabolic processGO:0046039720.039
neuron developmentGO:00486662860.039
cellular response to organonitrogen compoundGO:00714171970.039
central nervous system developmentGO:00074173110.038
dicarboxylic acid metabolic processGO:0043648420.038
organonitrogen compound biosynthetic processGO:19015661670.038
cellular response to stressGO:00335542690.038
response to glucoseGO:00097491360.037
inorganic cation transmembrane transportGO:00986622020.036
purine nucleotide metabolic processGO:00061632290.035
nucleoside phosphate biosynthetic processGO:19012931020.035
purine ribonucleotide biosynthetic processGO:0009152810.035
transcription dna templatedGO:00063513770.035
monocarboxylic acid biosynthetic processGO:0072330480.034
positive regulation of neurogenesisGO:00507691650.034
negative regulation of apoptotic processGO:00430661810.034
cofactor biosynthetic processGO:0051188280.034
carbohydrate biosynthetic processGO:0016051420.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
hexose biosynthetic processGO:0019319150.033
peptidyl amino acid modificationGO:00181931260.033
positive regulation of molecular functionGO:00440932300.033
regulation of catalytic activityGO:00507903040.033
positive regulation of nucleobase containing compound metabolic processGO:00459353190.032
gliogenesisGO:0042063930.032
transmembrane transportGO:00550854120.032
rna metabolic processGO:00160704060.031
positive regulation of purine nucleotide metabolic processGO:1900544910.031
regulation of apoptotic processGO:00429813350.031
dicarboxylic acid catabolic processGO:004364910.030
small molecule biosynthetic processGO:00442831240.030
regulation of multicellular organismal developmentGO:20000263760.030
response to nutrientGO:00075842480.030
regulation of purine nucleotide metabolic processGO:19005421150.029
regulation of cellular localizationGO:00603412630.029
response to extracellular stimulusGO:00099913800.029
nucleoside triphosphate metabolic processGO:00091411440.028
purine ribonucleotide metabolic processGO:00091502270.028
response to temperature stimulusGO:0009266940.028
regulation of cellular ketone metabolic processGO:0010565270.028
citrate metabolic processGO:000610130.028
inorganic ion transmembrane transportGO:00986602290.028
regulation of transmembrane transportGO:00347621220.027
catabolic processGO:00090563510.027
cell cell signalingGO:00072673350.026
regulation of cellular protein metabolic processGO:00322682670.026
single organism organelle organizationGO:19025891800.026
regulation of ion transmembrane transporter activityGO:0032412480.026
cellular response to insulin stimulusGO:0032869810.025
response to campGO:0051591910.025
olfactory behaviorGO:004204820.025
muscle structure developmentGO:0061061870.025
lipid transportGO:0006869610.024
purine ribonucleoside monophosphate biosynthetic processGO:0009168200.024
regulation of protein modification processGO:00313991940.024
cellular cation homeostasisGO:00300031800.024
nitrogen compound transportGO:00717052290.024
positive regulation of protein export from nucleusGO:004682730.024
response to nutrient levelsGO:00316673700.024
divalent inorganic cation homeostasisGO:00725071650.024
intracellular transportGO:00469071850.023
monosaccharide biosynthetic processGO:0046364160.023
sexual reproductionGO:00199531480.023
organonitrogen compound catabolic processGO:19015651790.023
regulation of transferase activityGO:00513381230.023
response to metal ionGO:00100382530.023
regulation of transporter activityGO:0032409500.022
regulation of nervous system developmentGO:00519602640.022
purine nucleoside biosynthetic processGO:0042451210.022
olfactory learningGO:000835510.022
purine ribonucleoside monophosphate catabolic processGO:0009169550.022
glycogen biosynthetic processGO:0005978150.022
calcium ion transmembrane transportGO:0070588700.022
neuron projection developmentGO:00311752730.022
regulation of phosphatidylinositol dephosphorylationGO:006030410.022
positive regulation of nervous system developmentGO:00519621780.022
ribonucleoside biosynthetic processGO:0042455250.021
protein complex subunit organizationGO:00718223020.021
cellular response to peptide hormone stimulusGO:00713751200.021
regulation of phosphorylationGO:00423252480.021
carbohydrate derivative catabolic processGO:19011361470.021
purine nucleoside triphosphate metabolic processGO:00091441410.021
sensory perceptionGO:00076001010.021
transcription from rna polymerase ii promoterGO:00063662520.021
regulation of cell developmentGO:00602842630.021
cellular metal ion homeostasisGO:00068751720.020
response to oxidative stressGO:00069791860.020
response to carbohydrateGO:00097431830.020
cellular respirationGO:0045333210.020
macromolecular complex assemblyGO:00650032730.020
coenzyme biosynthetic processGO:0009108220.020
positive regulation of cellular biosynthetic processGO:00313282950.020
adp metabolic processGO:004603180.020
muscle system processGO:00030121150.020
cellular response to nitrogen compoundGO:19016992100.020
response to insulinGO:00328681330.019
regulation of hydrolase activityGO:00513361430.019
purine ribonucleotide catabolic processGO:00091541360.019
enzyme linked receptor protein signaling pathwayGO:00071671160.019
carbohydrate derivative biosynthetic processGO:19011371240.019
regulation of transcription dna templatedGO:00063553740.019
response to activityGO:0014823730.019
head developmentGO:00603222470.019
regulation of protein metabolic processGO:00512462890.019
neuron deathGO:00709971270.019
developmental process involved in reproductionGO:00030061590.019
aspartate family amino acid biosynthetic processGO:000906740.019
response to purine containing compoundGO:00140741260.019
mitochondrion organizationGO:0007005350.019
regulation of neuron maturationGO:001404130.019
negative regulation of molecular functionGO:00440921330.018
organic hydroxy compound metabolic processGO:19016151150.018
positive regulation of nucleotide metabolic processGO:0045981910.018
response to fatty acidGO:0070542650.018
regulation of transmembrane transporter activityGO:0022898490.018
purine nucleoside monophosphate biosynthetic processGO:0009127200.018
single organism reproductive processGO:00447022970.018
cellular amino acid catabolic processGO:0009063210.018
regulation of cell differentiationGO:00455953200.018
negative regulation of developmental processGO:00510931250.018
positive regulation of rna biosynthetic processGO:19026801970.018
tricarboxylic acid metabolic processGO:0072350100.018
negative regulation of protein metabolic processGO:00512481140.018
positive regulation of programmed cell deathGO:00430681570.017
regulation of calcium ion transmembrane transportGO:1903169180.017
reproductionGO:00000032450.017
acyl coa biosynthetic processGO:007161670.017
gluconeogenesisGO:0006094150.017
secretionGO:00469033070.017
dephosphorylationGO:0016311980.017
striated muscle contractionGO:0006941440.017
coenzyme metabolic processGO:0006732860.017
regulation of neurogenesisGO:00507672470.017
macromolecule localizationGO:00330362520.017
thioester metabolic processGO:0035383280.017
ribonucleoside catabolic processGO:00424541260.017
small molecule catabolic processGO:0044282590.017
positive regulation of cyclic nucleotide metabolic processGO:0030801370.017
regulation of gluconeogenesisGO:000611140.017
axon cargo transportGO:000808810.017
response to amino acidGO:0043200750.017
actin filament based movementGO:0030048160.017
alpha amino acid metabolic processGO:1901605710.016
synaptic transmissionGO:00072682350.016
regulation of high voltage gated calcium channel activityGO:190184130.016
regulation of protein export from nucleusGO:004682540.016
purine nucleotide transportGO:001586530.016
organ formationGO:004864530.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
learning or memoryGO:0007611900.016
purine nucleoside diphosphate metabolic processGO:000913590.016
cell cycle processGO:0022402570.016
glucose homeostasisGO:0042593750.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
amine metabolic processGO:0009308380.016
regulation of necroptotic processGO:006054420.016
cellular response to oxygen containing compoundGO:19017013860.016
second messenger mediated signalingGO:0019932510.015
heart morphogenesisGO:000300730.015
axon developmentGO:0061564960.015
thioester biosynthetic processGO:003538470.015
regulation of cellular amine metabolic processGO:003323880.015
atp metabolic processGO:0046034720.015
developmental maturationGO:0021700250.015
forebrain developmentGO:0030900980.015
organelle organizationGO:00069962660.015
negative regulation of gene expressionGO:00106291990.015
lipid metabolic processGO:00066292830.015
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
brain developmentGO:00074202470.015
organic anion transportGO:00157111320.015
rna localizationGO:000640340.015
cellular ion homeostasisGO:00068731840.015
tissue developmentGO:00098882520.015
acetyl coa biosynthetic process from pyruvateGO:000608650.015
establishment of protein localizationGO:00451841410.015
regulation of system processGO:00440572080.015
ribonucleoside diphosphate biosynthetic processGO:0009188100.015
positive regulation of rna metabolic processGO:00512542030.015
cell cycleGO:00070491010.015
positive regulation of developmental processGO:00510942830.015
positive regulation of transcription dna templatedGO:00458931970.014
response to glucocorticoidGO:00513842230.014
cellular amine metabolic processGO:0044106380.014
ras protein signal transductionGO:0007265290.014
response to cytokineGO:00340972150.014
positive regulation of cellular component organizationGO:00511302000.014
cellular response to peptideGO:19016531330.014
circadian rhythmGO:0007623880.014
cytosolic calcium ion homeostasisGO:00514801400.014
multi organism reproductive processGO:00447032620.014
response to reactive oxygen speciesGO:00003021200.014
cellular sodium ion homeostasisGO:000688340.014
negative regulation of macromolecule biosynthetic processGO:00105581480.014
chemosensory behaviorGO:000763520.014
regulation of vesicle mediated transportGO:0060627810.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
aspartate family amino acid metabolic processGO:0009066100.014
regulation of cellular catabolic processGO:00313291010.014
protein complex biogenesisGO:00702712630.014
positive regulation of ion transportGO:0043270940.014
ribonucleotide catabolic processGO:00092611360.014
spermatogenesisGO:0007283990.013
specification of organ identityGO:001009220.013
glucan biosynthetic processGO:0009250150.013
telencephalon developmentGO:0021537620.013
reproductive processGO:00224143720.013
adult locomotory behaviorGO:000834440.013
negative regulation of programmed cell deathGO:00430691830.013
male gamete generationGO:0048232990.013
microtubule cytoskeleton organizationGO:0000226250.013
negative regulation of cellular component organizationGO:0051129830.013
behaviorGO:00076102050.013
negative regulation of cell deathGO:00605482290.013
negative regulation of cellular metabolic processGO:00313242810.012
regulation of cell cycleGO:0051726730.012
organophosphate catabolic processGO:00464341480.012
glycolytic processGO:0006096170.012
regulation of reactive oxygen species metabolic processGO:2000377260.012
response to bacteriumGO:00096172000.012
nucleoside triphosphate catabolic processGO:00091431230.012
tricarboxylic acid cycleGO:0006099110.012
single organism intracellular transportGO:19025821660.012
glycosyl compound biosynthetic processGO:1901659250.012
muscle organ developmentGO:0007517500.012
positive regulation of neuron differentiationGO:00456661260.012
regulation of neuron differentiationGO:00456642080.012
regulation of cellular response to stressGO:0080135490.012
regulation of sodium ion transmembrane transporter activityGO:200064940.012
sulfur compound metabolic processGO:0006790700.012
positive regulation of cell differentiationGO:00455972170.012
regulation of membrane potentialGO:00423911100.012
regulation of cellular component biogenesisGO:0044087860.012
positive regulation of apoptotic processGO:00430651540.012
neurotransmitter uptakeGO:000150430.012
cytoskeleton organizationGO:00070101110.012
multi multicellular organism processGO:00447061380.012
regulation of secretionGO:00510462240.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
circulatory system developmentGO:00723591340.012
protein complex assemblyGO:00064612630.012
cellular response to endogenous stimulusGO:00714953770.012
regulation of signal transductionGO:00099663180.012
regulation of nitric oxide synthase activityGO:005099980.012
cellular response to oxidative stressGO:0034599760.012
mesoderm developmentGO:000749820.012
response to alkaloidGO:00432791320.012
response to radiationGO:00093141370.012
regulation of cellular component organizationGO:00511283680.012
response to peptideGO:19016522920.012
response to other organismGO:00517072200.012
response to light stimulusGO:0009416520.012
cytoplasmic transportGO:00164821150.012
regulation of cellular amino acid metabolic processGO:000652120.012
nucleoside catabolic processGO:00091641260.011
cell morphogenesis involved in differentiationGO:00009041190.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
blood circulationGO:00080151830.011
nucleobase containing compound catabolic processGO:00346551520.011
tube developmentGO:0035295890.011
heterocycle catabolic processGO:00467001670.011
fatty acid biosynthetic processGO:0006633330.011
organ morphogenesisGO:0009887750.011
sodium ion transmembrane transportGO:0035725670.011
cellular glucose homeostasisGO:0001678660.011
reactive oxygen species biosynthetic processGO:190340980.011
cardiac chamber developmentGO:000320510.011
kidney developmentGO:0001822670.011
ion transmembrane transportGO:00342203650.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
negative regulation of rna biosynthetic processGO:19026791180.011
cardiac muscle contractionGO:0060048270.011
vesicle organizationGO:0016050290.011
cellular response to external stimulusGO:00714961180.011
cellular carbohydrate catabolic processGO:0044275200.011
multicellular organismal reproductive processGO:00486092330.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
establishment of vesicle localizationGO:0051650310.011
regulation of intracellular transportGO:0032386650.011
nucleotide biosynthetic processGO:0009165980.011
purine nucleoside monophosphate catabolic processGO:0009128550.011
positive regulation of cellular amine metabolic processGO:003324030.011
protein oligomerizationGO:00512591910.011
cell cycle g2 m phase transitionGO:004483960.011
cellular polysaccharide biosynthetic processGO:0033692150.011
regulation of intracellular signal transductionGO:19025312180.011
proteolysisGO:00065081750.011
cardiac ventricle developmentGO:000323110.011
cognitionGO:0050890920.011
purine nucleotide catabolic processGO:00061951360.011
hepaticobiliary system developmentGO:0061008900.011
regulation of purine nucleotide catabolic processGO:0033121650.011
single organism behaviorGO:00447081300.011
negative regulation of biosynthetic processGO:00098901680.011
regulation of anatomical structure sizeGO:00900661350.011
udp glucose metabolic processGO:000601130.010
response to acid chemicalGO:00011012220.010
protein processingGO:0016485680.010
epithelium developmentGO:0060429960.010
axis specificationGO:000979840.010
formation of primary germ layerGO:000170410.010
nucleoside phosphate catabolic processGO:19012921400.010
lipid storageGO:001991510.010
chromosome segregationGO:000705920.010
peptidyl serine phosphorylationGO:0018105330.010
spindle organizationGO:000705120.010
positive regulation of signalingGO:00230562700.010
response to toxic substanceGO:00096361330.010
regulation of protein kinase activityGO:00458591050.010
positive regulation of signal transductionGO:00099671750.010
negative regulation of transportGO:00510511360.010
glutamine family amino acid biosynthetic processGO:000908420.010

Pfkm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.107
Human
disease of metabolismDOID:001466700.107
Human
nervous system diseaseDOID:86300.032
disease of anatomical entityDOID:700.032
central nervous system diseaseDOID:33100.032
amino acid metabolic disorderDOID:925200.028
carbohydrate metabolic disorderDOID:297800.015
Human
musculoskeletal system diseaseDOID:1700.011
acquired metabolic diseaseDOID:006015800.011