Rattus norvegicus

46 known processes

Pfkl

phosphofructokinase, liver

Pfkl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
generation of precursor metabolites and energyGO:0006091620.238
oxoacid metabolic processGO:00434362900.209
carbohydrate catabolic processGO:0016052400.159
carbohydrate metabolic processGO:00059751300.140
response to other organismGO:00517072200.133
single organism intracellular transportGO:19025821660.130
response to inorganic substanceGO:00100353770.119
oxidation reduction processGO:00551143040.101
single organism biosynthetic processGO:00447113420.094
single organism carbohydrate metabolic processGO:00447231180.090
monocarboxylic acid metabolic processGO:00327871520.089
carbohydrate derivative metabolic processGO:19011353460.088
negative regulation of cell deathGO:00605482290.087
single organism carbohydrate catabolic processGO:0044724400.087
negative regulation of apoptotic processGO:00430661810.083
carboxylic acid metabolic processGO:00197522890.083
liver developmentGO:0001889900.079
nucleotide metabolic processGO:00091172790.079
response to nutrient levelsGO:00316673700.079
organic acid metabolic processGO:00060822920.074
gland developmentGO:00487321550.072
organophosphate metabolic processGO:00196373700.068
organic substance catabolic processGO:19015753160.065
response to metal ionGO:00100382530.064
response to hypoxiaGO:00016662310.064
central nervous system developmentGO:00074173110.064
small molecule biosynthetic processGO:00442831240.064
negative regulation of programmed cell deathGO:00430691830.063
purine containing compound catabolic processGO:00725231380.060
response to corticosteroidGO:00319602350.058
nucleobase containing small molecule metabolic processGO:00550863160.058
regulation of programmed cell deathGO:00430673410.058
chemical homeostasisGO:00488782920.057
response to external biotic stimulusGO:00432072210.056
regulation of locomotionGO:00400121480.056
catabolic processGO:00090563510.054
g protein coupled receptor signaling pathwayGO:00071862420.054
nucleoside phosphate metabolic processGO:00067532830.054
purine containing compound metabolic processGO:00725212530.053
response to peptideGO:19016522920.053
organelle organizationGO:00069962660.053
protein phosphorylationGO:00064683450.053
regulation of protein metabolic processGO:00512462890.052
negative regulation of transportGO:00510511360.052
Mouse
response to carbohydrateGO:00097431830.051
Mouse
single organism catabolic processGO:00447122830.051
response to extracellular stimulusGO:00099913800.050
response to glucocorticoidGO:00513842230.049
response to cytokineGO:00340972150.048
membrane organizationGO:0061024940.048
organonitrogen compound catabolic processGO:19015651790.047
organonitrogen compound biosynthetic processGO:19015661670.046
intracellular transportGO:00469071850.046
single organism organelle organizationGO:19025891800.045
hepaticobiliary system developmentGO:0061008900.045
protein complex biogenesisGO:00702712630.045
programmed cell deathGO:00125013920.043
regulation of ion transportGO:00432692450.042
macromolecular complex subunit organizationGO:00439333390.042
protein complex assemblyGO:00064612630.041
glycosaminoglycan biosynthetic processGO:000602440.041
regulation of apoptotic processGO:00429813350.041
pyruvate metabolic processGO:0006090270.041
response to biotic stimulusGO:00096072260.041
regulation of molecular functionGO:00650093980.041
cellular component movementGO:00069282480.040
organ regenerationGO:00311001010.040
ribonucleoside triphosphate metabolic processGO:00091991410.040
homeostatic processGO:00425923310.040
cellular chemical homeostasisGO:00550822470.040
purine ribonucleotide catabolic processGO:00091541360.039
purine ribonucleoside monophosphate metabolic processGO:0009167840.039
purine ribonucleoside metabolic processGO:00461281680.039
response to oxygen levelsGO:00704822650.038
localization of cellGO:00516742020.037
apoptotic processGO:00069153810.037
single organism membrane organizationGO:0044802740.036
ribonucleotide metabolic processGO:00092592310.036
response to peptide hormoneGO:00434342780.036
calcium ion homeostasisGO:00550741620.034
purine ribonucleoside triphosphate metabolic processGO:00092051400.034
organophosphate catabolic processGO:00464341480.034
positive regulation of response to stimulusGO:00485842850.034
nucleoside triphosphate metabolic processGO:00091411440.034
cellular response to hormone stimulusGO:00328702470.034
agingGO:00075682410.034
negative regulation of signalingGO:00230571570.033
Mouse
purine ribonucleoside catabolic processGO:00461301240.033
cellular response to oxygen containing compoundGO:19017013860.033
response to heatGO:0009408600.032
cellular amino acid metabolic processGO:00065201070.032
insulin like growth factor receptor signaling pathwayGO:004800930.032
defense responseGO:00069521940.032
cell type specific apoptotic processGO:00972851340.031
response to estrogenGO:00436272320.031
cellular catabolic processGO:00442482950.031
regulation of catalytic activityGO:00507903040.031
locomotionGO:00400112370.031
response to monosaccharideGO:00342841590.030
Mouse
purine nucleoside metabolic processGO:00422781690.030
neuron projection developmentGO:00311752730.029
ribose phosphate metabolic processGO:00196932350.029
metal ion homeostasisGO:00550651860.029
brain developmentGO:00074202470.029
response to acid chemicalGO:00011012220.029
purine ribonucleotide metabolic processGO:00091502270.029
regenerationGO:00310991630.029
olfactory behaviorGO:004204820.029
regulation of hormone levelsGO:00108171870.028
Mouse
monosaccharide metabolic processGO:0005996610.028
carbohydrate derivative catabolic processGO:19011361470.028
cation transportGO:00068123820.027
regulation of cellular protein metabolic processGO:00322682670.027
ribonucleoside metabolic processGO:00091191740.027
positive regulation of rna biosynthetic processGO:19026801970.027
neuron differentiationGO:00301823680.027
transmembrane transportGO:00550854120.027
regulation of immune system processGO:00026821230.026
neural crest cell developmentGO:001403220.026
cellular ion homeostasisGO:00068731840.026
positive regulation of cellular amine metabolic processGO:003324030.026
regulation of muscle system processGO:0090257790.026
regulation of membrane potentialGO:00423911100.026
tube formationGO:003514830.025
cellular response to nitrogen compoundGO:19016992100.025
amine metabolic processGO:0009308380.025
regulation of cell developmentGO:00602842630.025
regulation of hydrolase activityGO:00513361430.025
negative regulation of metabolic processGO:00098923310.025
response to decreased oxygen levelsGO:00362932370.024
head developmentGO:00603222470.024
g protein coupled receptor internalizationGO:000203130.024
aromatic compound catabolic processGO:00194391680.024
response to oxidative stressGO:00069791860.024
tissue developmentGO:00098882520.024
cell motilityGO:00488702020.024
protein complex subunit organizationGO:00718223020.024
gtp metabolic processGO:0046039720.024
cellular response to external stimulusGO:00714961180.024
nucleoside metabolic processGO:00091161790.023
positive regulation of cell proliferationGO:00082842490.023
positive regulation of nucleobase containing compound metabolic processGO:00459353190.023
carbohydrate derivative biosynthetic processGO:19011371240.023
nucleoside phosphate catabolic processGO:19012921400.023
response to hexoseGO:00097461440.023
Mouse
b cell activation involved in immune responseGO:000231210.023
response to radiationGO:00093141370.023
monovalent inorganic cation transportGO:00156721720.023
cation homeostasisGO:00550801950.023
neurological system processGO:00508772190.023
purine nucleoside triphosphate metabolic processGO:00091441410.023
positive regulation of immune system processGO:0002684900.023
cellular homeostasisGO:00197252520.022
nucleotide catabolic processGO:00091661390.022
gtp catabolic processGO:0006184710.022
response to glucoseGO:00097491360.021
Mouse
multi multicellular organism processGO:00447061380.021
behaviorGO:00076102050.021
secretionGO:00469033070.021
Mouse
cellular amine metabolic processGO:0044106380.021
purine nucleotide biosynthetic processGO:0006164830.021
glycosyl compound metabolic processGO:19016571820.021
purine ribonucleoside triphosphate catabolic processGO:00092071220.021
cytosolic calcium ion homeostasisGO:00514801400.020
heart morphogenesisGO:000300730.020
positive regulation of cell migrationGO:0030335960.020
regulation of cellular localizationGO:00603412630.020
Mouse
positive regulation of cellular component movementGO:00512721020.020
metal ion transportGO:00300012890.020
cellular response to abiotic stimulusGO:0071214850.019
cellular response to peptideGO:19016531330.019
negative regulation of secretionGO:0051048820.019
Mouse
cell cycle checkpointGO:000007520.019
macromolecular complex assemblyGO:00650032730.019
response to ammonium ionGO:0060359710.019
cellular response to stressGO:00335542690.019
ribonucleoside catabolic processGO:00424541260.019
neuron developmentGO:00486662860.019
cell projection organizationGO:00300303020.019
positive regulation of biosynthetic processGO:00098913190.019
response to bacteriumGO:00096172000.019
response to woundingGO:00096112540.019
cellular ketone metabolic processGO:0042180510.019
regulation of ion transmembrane transportGO:00347651210.018
chemosensory behaviorGO:000763520.018
cellular cation homeostasisGO:00300031800.018
ribose phosphate biosynthetic processGO:0046390870.018
single fertilizationGO:000733830.018
regulation of purine nucleotide metabolic processGO:19005421150.018
protein oligomerizationGO:00512591910.018
regulation of cell differentiationGO:00455953200.018
negative regulation of cellular metabolic processGO:00313242810.018
establishment of protein localizationGO:00451841410.018
regulation of the force of heart contraction by chemical signalGO:000305720.017
peptide secretionGO:0002790860.017
Mouse
cellular carbohydrate metabolic processGO:0044262720.017
negative regulation of gene expressionGO:00106291990.017
nucleotide biosynthetic processGO:0009165980.017
nucleobase containing compound catabolic processGO:00346551520.017
female pregnancyGO:00075651220.017
single organism cellular localizationGO:19025801020.017
positive regulation of multicellular organismal processGO:00512403870.017
negative regulation of molecular functionGO:00440921330.017
nucleoside triphosphate catabolic processGO:00091431230.017
single organism behaviorGO:00447081300.017
purine containing compound biosynthetic processGO:0072522850.017
anatomical structure morphogenesisGO:00096532980.017
positive regulation of locomotionGO:00400171020.017
regulation of cellular amino acid metabolic processGO:000652120.016
reproductionGO:00000032450.016
response to alkaloidGO:00432791320.016
cellular calcium ion homeostasisGO:00068741600.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
multicellular organismal reproductive processGO:00486092330.016
regulation of metal ion transportGO:00109591180.016
multicellular organism reproductionGO:00325042330.016
regulation of mitochondrion organizationGO:001082170.016
aminoglycan biosynthetic processGO:000602340.016
negative regulation of rna splicingGO:003311930.016
regulation of phosphorus metabolic processGO:00511743490.016
ribonucleoside triphosphate catabolic processGO:00092031220.016
regulation of homeostatic processGO:00328441010.016
regulation of cellular component movementGO:00512701500.016
positive regulation of phosphorus metabolic processGO:00105622620.016
immune system processGO:00023762040.016
cellular response to growth factor stimulusGO:00713631620.016
smooth muscle cell proliferationGO:0048659770.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
positive regulation of gene expressionGO:00106282440.016
positive regulation of cellular component organizationGO:00511302000.016
neural crest cell differentiationGO:001403320.016
glycogen metabolic processGO:0005977230.016
response to insulinGO:00328681330.016
regulation of peptide secretionGO:0002791820.016
Mouse
reproductive system developmentGO:00614581280.016
ion transmembrane transportGO:00342203650.016
regulation of cell proliferationGO:00421273590.015
cellular metal ion homeostasisGO:00068751720.015
transcription dna templatedGO:00063513770.015
response to nutrientGO:00075842480.015
regulation of rna biosynthetic processGO:20011413810.015
heterocycle catabolic processGO:00467001670.015
purine nucleotide metabolic processGO:00061632290.015
cellular response to endogenous stimulusGO:00714953770.015
action potentialGO:0001508540.015
proteolysisGO:00065081750.015
peptide transportGO:0015833970.015
Mouse
regulation of dna metabolic processGO:0051052600.015
divalent inorganic cation homeostasisGO:00725071650.015
immune responseGO:00069551040.015
ion homeostasisGO:00508012120.015
positive regulation of developmental processGO:00510942830.015
regulation of response to external stimulusGO:00321011060.015
ribonucleotide catabolic processGO:00092611360.015
endoplasmic reticulum organizationGO:000702910.015
negative regulation of cell communicationGO:00106481580.015
Mouse
regulation of blood pressureGO:0008217830.015
regulation of nucleotide catabolic processGO:0030811650.014
neuronal action potentialGO:0019228350.014
regulation of synaptic transmissionGO:00508041410.014
cellular lipid metabolic processGO:00442552080.014
multicellular organismal signalingGO:0035637440.014
cellular response to peptide hormone stimulusGO:00713751200.014
regulation of blood circulationGO:19035221100.014
regulation of multicellular organismal developmentGO:20000263760.014
nucleic acid templated transcriptionGO:00976593790.014
response to amino acidGO:0043200750.014
adult locomotory behaviorGO:000834440.014
response to temperature stimulusGO:0009266940.014
organic cyclic compound catabolic processGO:19013611750.014
cellular component biogenesisGO:00440853680.014
response to growth factorGO:00708481890.014
forebrain developmentGO:0030900980.014
cellular response to organonitrogen compoundGO:00714171970.014
negative regulation of catalytic activityGO:00430861030.014
regulation of secretion by cellGO:19035302080.014
Mouse
cellular response to insulin stimulusGO:0032869810.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
positive regulation of protein metabolic processGO:00512471780.014
cellular response to organic cyclic compoundGO:00714072020.014
response to starvationGO:0042594590.014
vesicle mediated transportGO:00161921810.013
regulation of cellular component organizationGO:00511283680.013
epithelium developmentGO:0060429960.013
negative regulation of mitotic cell cycle phase transitionGO:190199130.013
regulation of smooth muscle cell proliferationGO:0048660750.013
ribonucleoside monophosphate metabolic processGO:0009161880.013
positive regulation of nucleotide metabolic processGO:0045981910.013
lipid metabolic processGO:00066292830.013
circulatory system processGO:00030131830.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
fertilizationGO:000956630.013
ras protein signal transductionGO:0007265290.013
sulfur compound biosynthetic processGO:0044272190.013
regulation of cell motilityGO:20001451310.013
positive regulation of cellular biosynthetic processGO:00313282950.013
positive regulation of cell communicationGO:00106472710.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
transmission of nerve impulseGO:0019226420.013
neural tube formationGO:000184110.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
protein heterooligomerizationGO:0051291890.013
spermatogenesisGO:0007283990.013
glucose metabolic processGO:0006006520.013
muscle system processGO:00030121150.013
sensory organ developmentGO:0007423740.012
regulation of cellular ketone metabolic processGO:0010565270.012
regulation of behaviorGO:0050795610.012
negative regulation of ion transportGO:0043271510.012
synaptic growth at neuromuscular junctionGO:005112410.012
nucleoside phosphate biosynthetic processGO:19012931020.012
innate immune responseGO:0045087350.012
cellular response to extracellular stimulusGO:0031668730.012
carbohydrate phosphorylationGO:0046835160.012
regulation of anatomical structure sizeGO:00900661350.012
peptidyl amino acid modificationGO:00181931260.012
rhythmic processGO:00485111560.012
response to ketoneGO:19016541820.012
regulation of protein maturationGO:1903317500.012
blood circulationGO:00080151830.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.012
organophosphate biosynthetic processGO:00904071430.012
neuron neuron synaptic transmissionGO:0007270600.012
anion transportGO:00068201780.012
regulation of cell migrationGO:00303341280.012
regulation of transcription dna templatedGO:00063553740.012
sexual reproductionGO:00199531480.012
regulation of immunoglobulin productionGO:000263740.012
negative regulation of neuron deathGO:1901215690.012
nitrogen compound transportGO:00717052290.011
Mouse
axis specificationGO:000979840.011
cell cycleGO:00070491010.011
multi organism reproductive processGO:00447032620.011
regulation of system processGO:00440572080.011
positive regulation of cell motilityGO:2000147970.011
negative regulation of macromolecule metabolic processGO:00106052600.011
cellular response to oxygen levelsGO:0071453600.011
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.011
positive regulation of b cell mediated immunityGO:000271420.011
response to estradiolGO:00323551640.011
sex differentiationGO:00075481130.011
developmental process involved in reproductionGO:00030061590.011
negative regulation of protein metabolic processGO:00512481140.011
neural crest cell migrationGO:000175510.011
negative regulation of proteolysisGO:0045861410.011
regulation of cell projection organizationGO:00313441750.011
cellular glucan metabolic processGO:0006073230.011
cell migrationGO:00164771970.011
response to activityGO:0014823730.011
regulation of nucleotide metabolic processGO:00061401170.011
energy derivation by oxidation of organic compoundsGO:0015980460.011
ribonucleotide biosynthetic processGO:0009260850.011
rna biosynthetic processGO:00327743800.011
regulation of neuron differentiationGO:00456642080.011
hormone secretionGO:00468791150.011
Mouse
regulation of arp2 3 complex mediated actin nucleationGO:003431520.011
response to interleukin 1GO:0070555550.011
positive regulation of organelle organizationGO:0010638480.011
regulation of rna metabolic processGO:00512523910.011
reproductive processGO:00224143720.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
negative regulation of cell cycle phase transitionGO:190198840.011
negative regulation of cell proliferationGO:00082851190.010
negative regulation of cellular protein metabolic processGO:00322691060.010
purine nucleoside catabolic processGO:00061521240.010
regulation of hormone secretionGO:00468831060.010
Mouse
positive regulation of cell developmentGO:00107201760.010
cytoplasmic transportGO:00164821150.010
cellular nitrogen compound catabolic processGO:00442701630.010
cell cell signalingGO:00072673350.010
Mouse
single organism reproductive processGO:00447022970.010
sensory perceptionGO:00076001010.010
purine nucleoside triphosphate catabolic processGO:00091461220.010
cellular response to hexose stimulusGO:0071331650.010
behavioral response to ethanolGO:004814910.010
vesicle organizationGO:0016050290.010
rna metabolic processGO:00160704060.010
response to uv cGO:001022520.010
reactive oxygen species biosynthetic processGO:190340980.010

Pfkl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.027
disease of cellular proliferationDOID:1456600.027
gastrointestinal system cancerDOID:311900.027
organ system cancerDOID:005068600.027
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.026
intestinal cancerDOID:1015500.019
large intestine cancerDOID:567200.019
colorectal cancerDOID:925600.019
colon cancerDOID:21900.019
colon carcinomaDOID:152000.019
thoracic cancerDOID:509300.012
breast cancerDOID:161200.012
central nervous system diseaseDOID:33100.011