Rattus norvegicus

0 known processes

Mapkapk2

mitogen-activated protein kinase-activated protein kinase 2

Mapkapk2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201070.295
rna metabolic processGO:00160704060.172
carboxylic acid metabolic processGO:00197522890.172
nucleic acid templated transcriptionGO:00976593790.160
response to molecule of bacterial originGO:00022371940.121
programmed cell deathGO:00125013920.119
regulation of rna metabolic processGO:00512523910.118
cellular response to biotic stimulusGO:0071216590.113
regulation of signal transductionGO:00099663180.109
secretionGO:00469033070.109
negative regulation of cell deathGO:00605482290.109
regulation of rna biosynthetic processGO:20011413810.108
regulation of transcription dna templatedGO:00063553740.102
apoptotic processGO:00069153810.099
regulation of apoptotic processGO:00429813350.096
protein phosphorylationGO:00064683450.092
Human
regulation of intracellular signal transductionGO:19025312180.089
negative regulation of signalingGO:00230571570.086
regulation of protein metabolic processGO:00512462890.084
response to lipopolysaccharideGO:00324961910.083
organic acid metabolic processGO:00060822920.080
transcription from rna polymerase ii promoterGO:00063662520.079
protein complex assemblyGO:00064612630.076
response to external biotic stimulusGO:00432072210.075
negative regulation of apoptotic processGO:00430661810.072
positive regulation of nitrogen compound metabolic processGO:00511733340.072
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.071
regulation of cellular protein metabolic processGO:00322682670.071
organic substance catabolic processGO:19015753160.070
regulation of cell differentiationGO:00455953200.070
positive regulation of rna metabolic processGO:00512542030.069
tissue developmentGO:00098882520.068
transcription dna templatedGO:00063513770.068
response to bacteriumGO:00096172000.068
oxoacid metabolic processGO:00434362900.067
positive regulation of biosynthetic processGO:00098913190.067
regulation of nucleic acid templated transcriptionGO:19035063800.066
negative regulation of rna metabolic processGO:00512531230.066
rna biosynthetic processGO:00327743800.064
intracellular signal transductionGO:00355563140.061
positive regulation of nucleobase containing compound metabolic processGO:00459353190.058
anatomical structure morphogenesisGO:00096532980.058
regulation of secretion by cellGO:19035302080.058
negative regulation of macromolecule metabolic processGO:00106052600.057
regulation of molecular functionGO:00650093980.056
response to other organismGO:00517072200.056
regulation of fat cell differentiationGO:004559830.055
positive regulation of cellular protein metabolic processGO:00322701670.055
response to inorganic substanceGO:00100353770.054
response to oxidative stressGO:00069791860.053
single organism catabolic processGO:00447122830.053
cellular ketone metabolic processGO:0042180510.052
catabolic processGO:00090563510.052
organophosphate metabolic processGO:00196373700.052
response to growth factorGO:00708481890.051
Human
agingGO:00075682410.051
amine metabolic processGO:0009308380.051
regulation of cellular localizationGO:00603412630.051
regulation of secretionGO:00510462240.050
regulation of phosphate metabolic processGO:00192203490.050
negative regulation of metabolic processGO:00098923310.049
regulation of response to stressGO:00801341260.049
negative regulation of developmental processGO:00510931250.049
purine containing compound metabolic processGO:00725212530.048
negative regulation of cellular metabolic processGO:00313242810.048
regulation of transcription from rna polymerase ii promoterGO:00063572340.048
mapk cascadeGO:00001651400.048
negative regulation of nitrogen compound metabolic processGO:00511721610.047
carbohydrate derivative metabolic processGO:19011353460.047
cellular amine metabolic processGO:0044106380.047
regulation of cellular ketone metabolic processGO:0010565270.046
positive regulation of transcription dna templatedGO:00458931970.045
secretion by cellGO:00329402480.045
regulation of programmed cell deathGO:00430673410.045
negative regulation of gene expressionGO:00106291990.044
regulation of proteasomal protein catabolic processGO:006113640.044
negative regulation of cell communicationGO:00106481580.044
response to oxygen levelsGO:00704822650.044
cellular catabolic processGO:00442482950.043
regulation of cell developmentGO:00602842630.043
regulation of hormone secretionGO:00468831060.043
positive regulation of gene expressionGO:00106282440.042
positive regulation of cell communicationGO:00106472710.042
positive regulation of nucleic acid templated transcriptionGO:19035081970.041
cellular response to organonitrogen compoundGO:00714171970.041
cellular response to lipopolysaccharideGO:0071222550.040
positive regulation of developmental processGO:00510942830.040
nucleoside phosphate metabolic processGO:00067532830.039
cellular homeostasisGO:00197252520.039
positive regulation of response to stimulusGO:00485842850.038
positive regulation of cellular biosynthetic processGO:00313282950.038
positive regulation of protein metabolic processGO:00512471780.038
positive regulation of transportGO:00510502450.038
response to extracellular stimulusGO:00099913800.037
regulation of mapk cascadeGO:00434081160.037
response to biotic stimulusGO:00096072260.037
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.037
Human
positive regulation of signalingGO:00230562700.037
negative regulation of response to stimulusGO:00485851550.037
regulation of phosphorylationGO:00423252480.037
negative regulation of programmed cell deathGO:00430691830.036
cellular response to oxygen containing compoundGO:19017013860.036
response to decreased oxygen levelsGO:00362932370.036
chemical homeostasisGO:00488782920.036
negative regulation of cellular biosynthetic processGO:00313271610.036
regulation of cellular amino acid metabolic processGO:000652120.036
cellular component assemblyGO:00226073600.035
cellular response to hormone stimulusGO:00328702470.035
peptidyl amino acid modificationGO:00181931260.035
Human
negative regulation of biosynthetic processGO:00098901680.034
regulation of catabolic processGO:00098941130.034
macromolecular complex subunit organizationGO:00439333390.033
regulation of cell proliferationGO:00421273590.033
homeostatic processGO:00425923310.033
positive regulation of secretionGO:00510471400.033
regulation of hormone levelsGO:00108171870.033
organic anion transportGO:00157111320.032
positive regulation of molecular functionGO:00440932300.031
cellular response to endogenous stimulusGO:00714953770.031
response to insulinGO:00328681330.031
positive regulation of rna biosynthetic processGO:19026801970.031
response to nutrient levelsGO:00316673700.031
response to peptideGO:19016522920.030
negative regulation of rna biosynthetic processGO:19026791180.030
nucleotide metabolic processGO:00091172790.030
carboxylic acid transportGO:00469421150.030
neuron deathGO:00709971270.030
nitrogen compound transportGO:00717052290.030
positive regulation of cellular catabolic processGO:0031331710.030
regulation of catalytic activityGO:00507903040.030
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.030
regulation of phosphorus metabolic processGO:00511743490.030
defense responseGO:00069521940.030
single organism biosynthetic processGO:00447113420.029
cellular response to molecule of bacterial originGO:0071219560.029
brain developmentGO:00074202470.029
cellular chemical homeostasisGO:00550822470.029
regulation of protein localizationGO:0032880810.029
positive regulation of cellular amino acid metabolic processGO:004576410.029
positive regulation of macromolecule biosynthetic processGO:00105572470.028
positive regulation of cellular amine metabolic processGO:003324030.028
muscle system processGO:00030121150.028
positive regulation of cell proliferationGO:00082842490.028
macromolecule localizationGO:00330362520.028
multicellular organism growthGO:003526410.028
regulation of protein phosphorylationGO:00019321830.028
signal transduction by phosphorylationGO:00230141440.028
divalent inorganic cation homeostasisGO:00725071650.028
single organism reproductive processGO:00447022970.027
response to hypoxiaGO:00016662310.027
amide transportGO:00428861050.027
nucleobase containing small molecule metabolic processGO:00550863160.027
protein complex subunit organizationGO:00718223020.027
positive regulation of cell differentiationGO:00455972170.027
organophosphate biosynthetic processGO:00904071430.027
macromolecular complex assemblyGO:00650032730.026
cellular calcium ion homeostasisGO:00068741600.026
regulation of system processGO:00440572080.026
purine nucleotide biosynthetic processGO:0006164830.026
reproductive processGO:00224143720.026
regulation of cellular response to stressGO:0080135490.026
response to organophosphorusGO:00466831020.026
regulation of kinase activityGO:00435491170.025
protein transportGO:00150311320.025
hormone transportGO:00099141210.025
regulation of ion transportGO:00432692450.025
nucleoside phosphate biosynthetic processGO:19012931020.025
positive regulation of protein phosphorylationGO:00019341350.025
negative regulation of macromolecule biosynthetic processGO:00105581480.025
negative regulation of multicellular organismal processGO:00512412030.025
response to peptide hormoneGO:00434342780.024
regulation of cellular component organizationGO:00511283680.024
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.024
peptide transportGO:0015833970.024
glycosyl compound metabolic processGO:19016571820.024
regulation of protein modification processGO:00313991940.024
organic acid transportGO:00158491160.024
epithelium developmentGO:0060429960.024
positive regulation of apoptotic processGO:00430651540.024
purine nucleotide metabolic processGO:00061632290.023
cellular macromolecule localizationGO:00707271220.023
organonitrogen compound biosynthetic processGO:19015661670.023
positive regulation of secretion by cellGO:19035321280.023
response to campGO:0051591910.023
cytokine productionGO:0001816610.023
Human
cellular response to nitrogen compoundGO:19016992100.023
organelle organizationGO:00069962660.023
rhythmic processGO:00485111560.023
protein oligomerizationGO:00512591910.023
neuron differentiationGO:00301823680.023
purine ribonucleotide biosynthetic processGO:0009152810.023
signal releaseGO:00230611450.023
ribonucleotide biosynthetic processGO:0009260850.022
peptide biosynthetic processGO:004304330.022
regulation of multicellular organismal developmentGO:20000263760.022
positive regulation of programmed cell deathGO:00430681570.022
gastrulationGO:000736920.022
nucleobase containing compound catabolic processGO:00346551520.022
positive regulation of cell deathGO:00109421840.022
central nervous system developmentGO:00074173110.022
positive regulation of multicellular organismal processGO:00512403870.022
prostaglandin transportGO:001573280.022
ribonucleotide metabolic processGO:00092592310.022
axis specificationGO:000979840.021
ion homeostasisGO:00508012120.021
anion transportGO:00068201780.021
hormone secretionGO:00468791150.021
carbohydrate derivative biosynthetic processGO:19011371240.021
cell cell signalingGO:00072673350.021
tube developmentGO:0035295890.021
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
cellular response to stressGO:00335542690.021
Human
cellular nitrogen compound catabolic processGO:00442701630.021
response to acid chemicalGO:00011012220.020
response to reactive oxygen speciesGO:00003021200.020
multicellular organismal reproductive processGO:00486092330.020
cation homeostasisGO:00550801950.020
regulation of peptide transportGO:0090087870.020
purine ribonucleotide metabolic processGO:00091502270.020
proteolysisGO:00065081750.020
positive regulation of cell developmentGO:00107201760.020
vesicle mediated transportGO:00161921810.020
regulation of purine nucleotide metabolic processGO:19005421150.020
multi organism reproductive processGO:00447032620.020
organonitrogen compound catabolic processGO:19015651790.020
response to radiationGO:00093141370.020
regulation of establishment of protein localizationGO:0070201690.020
regulation of neuron deathGO:19012141150.019
cytoskeleton organizationGO:00070101110.019
metal ion homeostasisGO:00550651860.019
regulation of cellular amine metabolic processGO:003323880.019
ribose phosphate metabolic processGO:00196932350.019
positive regulation of cytosolic calcium ion concentrationGO:00072041220.019
g protein coupled receptor signaling pathwayGO:00071862420.019
regulation of transferase activityGO:00513381230.019
protein complex biogenesisGO:00702712630.019
intracellular protein transportGO:0006886790.018
response to ketoneGO:19016541820.018
positive regulation of nervous system developmentGO:00519621780.018
regulation of neurogenesisGO:00507672470.018
circulatory system developmentGO:00723591340.018
cellular metal ion homeostasisGO:00068751720.018
negative regulation of signal transductionGO:0009968830.018
ribose phosphate biosynthetic processGO:0046390870.018
monovalent inorganic cation transportGO:00156721720.018
positive regulation of catalytic activityGO:00430851840.018
positive regulation of phosphate metabolic processGO:00459372620.018
regulation of nervous system developmentGO:00519602640.018
nuclear importGO:0051170350.018
response to hexoseGO:00097461440.018
protein localizationGO:00081041910.018
regulation of protein kinase activityGO:00458591050.018
cyclic nucleotide metabolic processGO:0009187800.018
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.018
positive regulation of protein modification processGO:00314011420.017
cellular response to growth factor stimulusGO:00713631620.017
Human
cellular component biogenesisGO:00440853680.017
response to carbohydrateGO:00097431830.017
endocytosisGO:0006897840.017
response to glucoseGO:00097491360.017
negative regulation of cell differentiationGO:0045596990.017
regulation of neuron apoptotic processGO:0043523830.017
circulatory system processGO:00030131830.017
positive regulation of phosphorus metabolic processGO:00105622620.017
neuron developmentGO:00486662860.017
cellular response to oxidative stressGO:0034599760.016
positive regulation of intracellular signal transductionGO:19025331380.016
cation transportGO:00068123820.016
generation of precursor metabolites and energyGO:0006091620.016
response to nutrientGO:00075842480.016
peptide secretionGO:0002790860.016
protein import into nucleusGO:0006606350.016
negative regulation of protein metabolic processGO:00512481140.016
cellular response to organic cyclic compoundGO:00714072020.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
calcium ion homeostasisGO:00550741620.016
regulation of membrane potentialGO:00423911100.016
oxidation reduction processGO:00551143040.016
amino acid transportGO:0006865700.016
response to metal ionGO:00100382530.016
regulation of protein transportGO:0051223680.016
neuron apoptotic processGO:0051402880.015
reproductive structure developmentGO:00486081280.015
purine containing compound biosynthetic processGO:0072522850.015
immune responseGO:00069551040.015
cellular protein localizationGO:00346131220.015
action potentialGO:0001508540.015
cell cycle checkpointGO:000007520.015
Human
positive regulation of proteasomal protein catabolic processGO:190180030.015
divalent metal ion transportGO:00708381320.015
head developmentGO:00603222470.015
positive regulation of phosphorylationGO:00423271770.015
cellular cation homeostasisGO:00300031800.015
positive regulation of kinase activityGO:0033674770.015
small gtpase mediated signal transductionGO:0007264360.015
nucleoside metabolic processGO:00091161790.015
negative regulation of molecular functionGO:00440921330.014
purine nucleoside metabolic processGO:00422781690.014
gamete generationGO:00072761240.014
cellular ion homeostasisGO:00068731840.014
cell adhesionGO:00071551100.014
developmental process involved in reproductionGO:00030061590.014
heterocycle catabolic processGO:00467001670.014
nucleoside phosphate catabolic processGO:19012921400.014
lipid transportGO:0006869610.014
regulation of cellular component biogenesisGO:0044087860.014
regulation of response to external stimulusGO:00321011060.014
nucleotide biosynthetic processGO:0009165980.014
alpha amino acid metabolic processGO:1901605710.014
regulation of peptide secretionGO:0002791820.014
regulation of cellular catabolic processGO:00313291010.014
reproductionGO:00000032450.014
reproductive system developmentGO:00614581280.014
regulation of peptide hormone secretionGO:0090276800.014
regulation of jnk cascadeGO:0046328190.014
purine ribonucleoside metabolic processGO:00461281680.014
response to cytokineGO:00340972150.014
Human
cellular divalent inorganic cation homeostasisGO:00725031620.014
regulation of nucleotide metabolic processGO:00061401170.014
cytoplasmic transportGO:00164821150.014
response to transition metal nanoparticleGO:19902671220.014
carbohydrate derivative catabolic processGO:19011361470.014
ras protein signal transductionGO:0007265290.014
cellular modified amino acid metabolic processGO:0006575610.014
response to cadmium ionGO:0046686350.013
lipid biosynthetic processGO:00086101280.013
positive regulation of cellular component organizationGO:00511302000.013
single organism carbohydrate metabolic processGO:00447231180.013
multicellular organism reproductionGO:00325042330.013
neuron projection developmentGO:00311752730.013
response to ethanolGO:00454711620.013
regulation of insulin secretionGO:0050796650.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
insulin secretionGO:0030073690.013
sexual reproductionGO:00199531480.013
biological adhesionGO:00226101100.013
protein heterooligomerizationGO:0051291890.013
positive regulation of protein kinase activityGO:0045860730.013
aromatic compound catabolic processGO:00194391680.013
lipid metabolic processGO:00066292830.013
response to mechanical stimulusGO:00096121340.013
hematopoietic progenitor cell differentiationGO:000224420.013
response to temperature stimulusGO:0009266940.013
heart developmentGO:0007507720.013
cell projection organizationGO:00300303020.013
negative regulation of transcription dna templatedGO:00458921160.013
negative regulation of neuron deathGO:1901215690.012
positive regulation of catabolic processGO:0009896780.012
regulation of muscle system processGO:0090257790.012
response to woundingGO:00096112540.012
metal ion transportGO:00300012890.012
skeletal system developmentGO:0001501410.012
renal system developmentGO:0072001670.012
positive regulation of transferase activityGO:0051347810.012
cytosolic calcium ion homeostasisGO:00514801400.012
negative regulation of phosphate metabolic processGO:0045936800.012
cytokine biosynthetic processGO:004208930.012
lipid localizationGO:0010876620.012
ribonucleoside metabolic processGO:00091191740.012
negative regulation of catalytic activityGO:00430861030.012
inflammatory responseGO:00069541500.012
protein targetingGO:0006605610.012
establishment of protein localizationGO:00451841410.012
regulation of blood vessel sizeGO:0050880890.012
cell type specific apoptotic processGO:00972851340.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
positive regulation of response to external stimulusGO:0032103510.012
response to alkaloidGO:00432791320.012
neurological system processGO:00508772190.012
positive regulation of signal transductionGO:00099671750.012
cellular response to reactive oxygen speciesGO:0034614550.012
negative regulation of transportGO:00510511360.012
peptide hormone secretionGO:0030072840.012
positive regulation of cytoplasmic transportGO:1903651320.011
organic cyclic compound catabolic processGO:19013611750.011
nucleotide catabolic processGO:00091661390.011
cellular response to lipidGO:00713962010.011
jnk cascadeGO:0007254280.011
regulation of map kinase activityGO:0043405530.011
positive regulation of ion transportGO:0043270940.011
acid secretionGO:0046717480.011
lipid storageGO:001991510.011
negative regulation of phosphorus metabolic processGO:0010563800.011
purine nucleoside monophosphate metabolic processGO:0009126840.011
single organism intracellular transportGO:19025821660.011
response to vitaminGO:00332731310.011
organophosphate catabolic processGO:00464341480.011
negative regulation of mitotic cell cycle phase transitionGO:190199130.011
purine nucleotide catabolic processGO:00061951360.011
regulation of defense responseGO:0031347680.011
cell growthGO:00160491040.011
cell activationGO:0001775970.011
carbohydrate homeostasisGO:0033500750.011
ribonucleotide catabolic processGO:00092611360.011
mirna metabolic processGO:001058610.011
muscle structure developmentGO:0061061870.011
intracellular transportGO:00469071850.011
spermatogenesisGO:0007283990.011
cellular lipid metabolic processGO:00442552080.011
purine ribonucleoside biosynthetic processGO:0046129210.011
response to glucocorticoidGO:00513842230.011
response to purine containing compoundGO:00140741260.011
regulation of transcription regulatory region dna bindingGO:200067740.011
maintenance of locationGO:0051235170.011
connective tissue developmentGO:0061448330.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
cellular response to cytokine stimulusGO:00713451270.011
regulation of canonical wnt signaling pathwayGO:006082840.011
ovulation cycle processGO:0022602500.011
macromolecule catabolic processGO:0009057580.010
neuronal action potentialGO:0019228350.010
cellular component morphogenesisGO:00329891550.010
membrane organizationGO:0061024940.010
glucose homeostasisGO:0042593750.010
negative regulation of cellular protein metabolic processGO:00322691060.010
single organism organelle organizationGO:19025891800.010
reactive nitrogen species metabolic processGO:200105710.010
carbohydrate metabolic processGO:00059751300.010
response to monosaccharideGO:00342841590.010
multicellular organismal signalingGO:0035637440.010
regulation of organic acid transportGO:0032890350.010
cell morphogenesisGO:00009021420.010
negative regulation of cellular response to insulin stimulusGO:1900077110.010
cellular response to carbohydrate stimulusGO:0071322720.010
embryonic pattern specificationGO:000988010.010
defense response to gram negative bacteriumGO:005082930.010
negative regulation of cell developmentGO:0010721820.010
cellular response to peptideGO:19016531330.010
negative regulation of insulin receptor signaling pathwayGO:0046627100.010

Mapkapk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.011