IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Ddx54

DEAD (Asp-Glu-Ala-Asp) box polypeptide 54

(Aliases: RGD1562539)

Entrez: 360815
Ensembl: ENSRNOG00000001377
RGD: 1562539
UniProtKB: D3ZHY6

Process Predictions
Disease Predictions

Ddx54 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
homeostatic process	GO:0042592	331	0.117
regulation of rna metabolic process	GO:0051252	391	0.088
chromosome segregation	GO:0007059	2	0.080
rna metabolic process	GO:0016070	406	0.078
mesoderm development	GO:0007498	2	0.070
regulation of transcription dna templated	GO:0006355	374	0.064
rna biosynthetic process	GO:0032774	380	0.063
nucleic acid templated transcription	GO:0097659	379	0.060
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.057
negative regulation of macromolecule metabolic process	GO:0010605	260	0.054
negative regulation of rna metabolic process	GO:0051253	123	0.047
transcription dna templated	GO:0006351	377	0.044
response to inorganic substance	GO:0010035	377	0.044
regulation of rna biosynthetic process	GO:2001141	381	0.042
meiotic cell cycle process	GO:1903046	3	0.036
negative regulation of cellular biosynthetic process	GO:0031327	161	0.033
glial cell differentiation	GO:0010001	65	0.032
regulation of mrna splicing via spliceosome	GO:0048024	3	0.032
negative regulation of cellular metabolic process	GO:0031324	281	0.031
immune response	GO:0006955	104	0.031
positive regulation of biosynthetic process	GO:0009891	319	0.030
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.030
response to growth factor	GO:0070848	189	0.030
protein complex subunit organization	GO:0071822	302	0.029
ion transmembrane transport	GO:0034220	365	0.029
gamete generation	GO:0007276	124	0.029
positive regulation of cell proliferation	GO:0008284	249	0.028
regulation of cell proliferation	GO:0042127	359	0.028
negative regulation of biosynthetic process	GO:0009890	168	0.028
brain development	GO:0007420	247	0.027
reproduction	GO:0000003	245	0.027
dna packaging	GO:0006323	4	0.027
embryonic skeletal system development	GO:0048706	3	0.026
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.026
regulation of nucleic acid templated transcription	GO:1903506	380	0.026
response to biotic stimulus	GO:0009607	226	0.024
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.024
macromolecular complex subunit organization	GO:0043933	339	0.024
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.024
negative regulation of metabolic process	GO:0009892	331	0.024
negative regulation of gene expression	GO:0010629	199	0.022
cation transport	GO:0006812	382	0.022
organelle organization	GO:0006996	266	0.021
positive regulation of cellular biosynthetic process	GO:0031328	295	0.021
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.021
sexual reproduction	GO:0019953	148	0.021
positive regulation of rna metabolic process	GO:0051254	203	0.020
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.020
positive regulation of gene expression	GO:0010628	244	0.020
cellular component biogenesis	GO:0044085	368	0.020
negative regulation of cell communication	GO:0010648	158	0.020
multicellular organismal reproductive process	GO:0048609	233	0.020
negative regulation of programmed cell death	GO:0043069	183	0.020
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.020
positive regulation of neurogenesis	GO:0050769	165	0.020
positive regulation of transcription dna templated	GO:0045893	197	0.019
reproductive process	GO:0022414	372	0.019
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.019
transcription from rna polymerase ii promoter	GO:0006366	252	0.019
gastrulation	GO:0007369	2	0.019
immune system process	GO:0002376	204	0.019
regulation of molecular function	GO:0065009	398	0.019
central nervous system development	GO:0007417	311	0.019
single organism reproductive process	GO:0044702	297	0.018
regulation of cellular localization	GO:0060341	263	0.018
leukocyte activation	GO:0045321	76	0.018
response to other organism	GO:0051707	220	0.018
multi organism reproductive process	GO:0044703	262	0.018
regulation of body fluid levels	GO:0050878	90	0.018
triglyceride homeostasis	GO:0070328	2	0.017
cellular homeostasis	GO:0019725	252	0.017
aging	GO:0007568	241	0.017
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.017
spermatogenesis	GO:0007283	99	0.017
regulation of alternative mrna splicing via spliceosome	GO:0000381	2	0.017
positive regulation of rna biosynthetic process	GO:1902680	197	0.017
gliogenesis	GO:0042063	93	0.016
cellular response to endogenous stimulus	GO:0071495	377	0.016
single organism intracellular transport	GO:1902582	166	0.016
response to mechanical stimulus	GO:0009612	134	0.016
alpha amino acid metabolic process	GO:1901605	71	0.016
response to metal ion	GO:0010038	253	0.016
negative regulation of transcription dna templated	GO:0045892	116	0.016
head development	GO:0060322	247	0.016
negative regulation of mitotic cell cycle phase transition	GO:1901991	3	0.015
sensory organ development	GO:0007423	74	0.015
carboxylic acid metabolic process	GO:0019752	289	0.015
leukocyte homeostasis	GO:0001776	7	0.015
amine metabolic process	GO:0009308	38	0.015
positive regulation of humoral immune response	GO:0002922	2	0.015
metal ion homeostasis	GO:0055065	186	0.015
cellular chemical homeostasis	GO:0055082	247	0.015
chemical homeostasis	GO:0048878	292	0.014
cellular calcium ion homeostasis	GO:0006874	160	0.014
protein complex biogenesis	GO:0070271	263	0.014
male gamete generation	GO:0048232	99	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.014
cell activation	GO:0001775	97	0.014
folic acid containing compound metabolic process	GO:0006760	10	0.014
cellular response to growth factor stimulus	GO:0071363	162	0.014
regulation of fat cell differentiation	GO:0045598	3	0.014
programmed cell death	GO:0012501	392	0.014
nucleobase containing small molecule metabolic process	GO:0055086	316	0.013
regulation of cell differentiation	GO:0045595	320	0.013
ncrna processing	GO:0034470	3	0.013
embryonic appendage morphogenesis	GO:0035113	4	0.013
negative regulation of rna biosynthetic process	GO:1902679	118	0.013
regulation of leukocyte proliferation	GO:0070663	26	0.013
anatomical structure morphogenesis	GO:0009653	298	0.013
axis specification	GO:0009798	4	0.013
negative regulation of cell cycle phase transition	GO:1901988	4	0.013
cellular response to cytokine stimulus	GO:0071345	127	0.013
embryonic skeletal system morphogenesis	GO:0048704	3	0.013
nucleoside phosphate biosynthetic process	GO:1901293	102	0.013
response to extracellular stimulus	GO:0009991	380	0.013
cellular amino acid metabolic process	GO:0006520	107	0.013
forebrain development	GO:0030900	98	0.013
positive regulation of cell differentiation	GO:0045597	217	0.013
protein oligomerization	GO:0051259	191	0.013
cellular ion homeostasis	GO:0006873	184	0.013
positive regulation of molecular function	GO:0044093	230	0.013
oxoacid metabolic process	GO:0043436	290	0.012
cytosolic calcium ion homeostasis	GO:0051480	140	0.012
regulation of odontogenesis	GO:0042481	4	0.012
cellular cation homeostasis	GO:0030003	180	0.012
chromosome organization	GO:0051276	36	0.012
negative regulation of transport	GO:0051051	136	0.012
regulation of cell growth	GO:0001558	85	0.012
proteolysis	GO:0006508	175	0.012
negative regulation of cell death	GO:0060548	229	0.012
pteridine containing compound metabolic process	GO:0042558	14	0.012
ion homeostasis	GO:0050801	212	0.012
multicellular organism reproduction	GO:0032504	233	0.012
macromolecular complex assembly	GO:0065003	273	0.012
regulation of protein metabolic process	GO:0051246	289	0.012
formation of primary germ layer	GO:0001704	1	0.012
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.012
cellular amine metabolic process	GO:0044106	38	0.012
actin filament organization	GO:0007015	42	0.012
cation transmembrane transport	GO:0098655	263	0.012
negative regulation of apoptotic process	GO:0043066	181	0.012
regeneration	GO:0031099	163	0.012
organic acid metabolic process	GO:0006082	292	0.011
cellular component assembly	GO:0022607	360	0.011
positive regulation of response to stimulus	GO:0048584	285	0.011
cellular ketone metabolic process	GO:0042180	51	0.011
peptide biosynthetic process	GO:0043043	3	0.011
wound healing	GO:0042060	122	0.011
regulation of response to stress	GO:0080134	126	0.011
negative regulation of rna splicing	GO:0033119	3	0.011
purine ribonucleotide metabolic process	GO:0009150	227	0.011
cellular response to nitrogen compound	GO:1901699	210	0.011
cellular response to hormone stimulus	GO:0032870	247	0.011
regulation of protein targeting	GO:1903533	28	0.011
cation homeostasis	GO:0055080	195	0.011
cell cell signaling involved in cell fate commitment	GO:0045168	2	0.011
palate development	GO:0060021	2	0.011
cellular response to insulin stimulus	GO:0032869	81	0.011
response to external biotic stimulus	GO:0043207	221	0.011
cellular modified amino acid biosynthetic process	GO:0042398	18	0.011
regulation of phosphorylation	GO:0042325	248	0.011
response to alkaloid	GO:0043279	132	0.011
positive regulation of jnk cascade	GO:0046330	13	0.010
secretion	GO:0046903	307	0.010
calcium ion homeostasis	GO:0055074	162	0.010
response to acid chemical	GO:0001101	222	0.010
positive regulation of cell development	GO:0010720	176	0.010
regulation of cell cycle g1 s phase transition	GO:1902806	7	0.010
regulation of proteasomal protein catabolic process	GO:0061136	4	0.010
regulation of neurogenesis	GO:0050767	247	0.010
regulation of catalytic activity	GO:0050790	304	0.010

Ddx54 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.026
nervous system disease	DOID:863	0.026
gastrointestinal system cancer	DOID:3119	0.024
organ system cancer	DOID:0050686	0.024
disease of cellular proliferation	DOID:14566	0.024
cancer	DOID:162	0.024
hepatocellular carcinoma	DOID:684	0.016
liver cancer	DOID:3571	0.016
liver carcinoma	DOID:686	0.016
central nervous system disease	DOID:331	0.011
sensory system disease	DOID:0050155	0.010

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