Rattus norvegicus

0 known processes

Sla

src-like adaptor

(Aliases: Slap1)

Sla biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune system processGO:00023762040.306
immune responseGO:00069551040.248
immune response regulating signaling pathwayGO:0002764190.167
cell activationGO:0001775970.165
regulation of platelet derived growth factor receptor signaling pathwayGO:001064020.157
cation homeostasisGO:00550801950.144
positive regulation of signalingGO:00230562700.140
ion homeostasisGO:00508012120.131
positive regulation of cell motilityGO:2000147970.129
immunoglobulin mediated immune responseGO:001606440.126
defense responseGO:00069521940.121
intracellular signal transductionGO:00355563140.117
response to biotic stimulusGO:00096072260.106
positive regulation of cell communicationGO:00106472710.103
single organism intracellular transportGO:19025821660.099
regulation of programmed cell deathGO:00430673410.098
metal ion homeostasisGO:00550651860.096
localization of cellGO:00516742020.092
regulation of b cell differentiationGO:004557710.091
calcium ion transport into cytosolGO:0060402380.091
divalent inorganic cation homeostasisGO:00725071650.089
positive regulation of response to stimulusGO:00485842850.089
cellular metal ion homeostasisGO:00068751720.086
regulation of immune system processGO:00026821230.085
positive regulation of signal transductionGO:00099671750.085
homeostatic processGO:00425923310.081
positive regulation of immune system processGO:0002684900.081
protein phosphorylationGO:00064683450.080
cellular amine metabolic processGO:0044106380.080
positive regulation of nitrogen compound metabolic processGO:00511733340.079
positive regulation of neurogenesisGO:00507691650.076
mapk cascadeGO:00001651400.076
positive regulation of intracellular signal transductionGO:19025331380.075
calcium ion homeostasisGO:00550741620.074
immune response regulating cell surface receptor signaling pathwayGO:0002768100.069
signal transduction by phosphorylationGO:00230141440.069
anatomical structure morphogenesisGO:00096532980.069
regulation of release of sequestered calcium ion into cytosolGO:0051279180.068
immune response activating signal transductionGO:0002757150.067
regulation of molecular functionGO:00650093980.067
leukocyte activationGO:0045321760.067
positive regulation of immune responseGO:0050778420.065
positive regulation of cell differentiationGO:00455972170.064
sequestering of metal ionGO:005123890.062
regulation of mapk cascadeGO:00434081160.060
regulation of intracellular signal transductionGO:19025312180.059
regulation of cellular amino acid metabolic processGO:000652120.059
regulation of phosphate metabolic processGO:00192203490.058
cellular ketone metabolic processGO:0042180510.055
cellular component biogenesisGO:00440853680.055
Yeast Rat
cation transportGO:00068123820.055
positive regulation of phosphate metabolic processGO:00459372620.054
positive regulation of transcription factor import into nucleusGO:004299340.053
sequestering of calcium ionGO:005120880.052
cellular amino acid metabolic processGO:00065201070.051
response to extracellular stimulusGO:00099913800.051
neuron differentiationGO:00301823680.051
cellular component movementGO:00069282480.050
protein localizationGO:00081041910.050
regulation of phosphorylationGO:00423252480.049
positive regulation of phosphorus metabolic processGO:00105622620.048
mast cell migrationGO:009753140.048
regulation of signal transductionGO:00099663180.048
single organism cellular localizationGO:19025801020.047
release of sequestered calcium ion into cytosolGO:0051209250.047
cellular divalent inorganic cation homeostasisGO:00725031620.047
neuron developmentGO:00486662860.046
dephosphorylationGO:0016311980.046
b cell differentiationGO:003018320.046
cellular ion homeostasisGO:00068731840.045
regulation of apoptotic processGO:00429813350.045
response to growth factorGO:00708481890.044
immune effector processGO:0002252530.044
cellular protein localizationGO:00346131220.043
cytokine biosynthetic processGO:004208930.042
apoptotic processGO:00069153810.042
cellular chemical homeostasisGO:00550822470.042
regulation of immune responseGO:0050776550.042
programmed cell deathGO:00125013920.041
cellular cation homeostasisGO:00300031800.040
negative regulation of cellular response to insulin stimulusGO:1900077110.039
positive regulation of programmed cell deathGO:00430681570.039
positive regulation of transportGO:00510502450.039
agingGO:00075682410.039
Rat
divalent metal ion transportGO:00708381320.038
multi organism reproductive processGO:00447032620.038
activation of immune responseGO:0002253260.038
regulation of protein transportGO:0051223680.037
positive regulation of developmental processGO:00510942830.037
negative regulation of metabolic processGO:00098923310.037
hematopoietic progenitor cell differentiationGO:000224420.036
regulation of cellular amine metabolic processGO:003323880.035
macromolecular complex subunit organizationGO:00439333390.035
Yeast Rat
cellular calcium ion homeostasisGO:00068741600.035
cytoplasmic transportGO:00164821150.034
establishment of protein localizationGO:00451841410.034
regulation of rna metabolic processGO:00512523910.034
cell motilityGO:00488702020.034
protein complex biogenesisGO:00702712630.034
Yeast Rat
regulation of protein phosphorylationGO:00019321830.034
metal ion transportGO:00300012890.034
protein complex subunit organizationGO:00718223020.034
Yeast Rat
macromolecule localizationGO:00330362520.033
amine metabolic processGO:0009308380.033
neuron deathGO:00709971270.033
response to bacteriumGO:00096172000.033
response to oxygen levelsGO:00704822650.033
single organism reproductive processGO:00447022970.033
cellular macromolecule localizationGO:00707271220.033
positive regulation of phosphorylationGO:00423271770.032
lymphocyte activationGO:0046649430.032
regulation of transcription dna templatedGO:00063553740.032
cellular response to cytokine stimulusGO:00713451270.032
positive regulation of cellular biosynthetic processGO:00313282950.032
cytosolic calcium ion homeostasisGO:00514801400.032
calcium ion transportGO:00068161310.032
regulation of cell differentiationGO:00455953200.032
chemical homeostasisGO:00488782920.031
organic acid metabolic processGO:00060822920.031
regulation of catalytic activityGO:00507903040.031
regulation of cytokine biosynthetic processGO:004203530.031
peptidyl amino acid modificationGO:00181931260.031
cellular response to stressGO:00335542690.031
response to external biotic stimulusGO:00432072210.031
cell cell signalingGO:00072673350.030
negative regulation of response to stimulusGO:00485851550.030
cell substrate adhesionGO:0031589290.029
regulation of neurogenesisGO:00507672470.029
positive regulation of cytosolic calcium ion concentrationGO:00072041220.029
cell type specific apoptotic processGO:00972851340.029
reproductive processGO:00224143720.029
b cell mediated immunityGO:001972440.029
positive regulation of biosynthetic processGO:00098913190.029
cell migrationGO:00164771970.028
regulation of intracellular transportGO:0032386650.028
positive regulation of rna metabolic processGO:00512542030.028
positive regulation of apoptotic processGO:00430651540.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.027
leukocyte mediated immunityGO:0002443280.027
salivary gland morphogenesisGO:000743510.027
g protein coupled receptor signaling pathwayGO:00071862420.027
positive regulation of neuron differentiationGO:00456661260.027
regulation of neuron apoptotic processGO:0043523830.027
multicellular organismal reproductive processGO:00486092330.027
response to alkyl hydroperoxideGO:003319510.027
response to insulinGO:00328681330.027
positive regulation of cell activationGO:0050867340.027
secretion by cellGO:00329402480.027
regulation of neuron deathGO:19012141150.026
response to decreased oxygen levelsGO:00362932370.026
head developmentGO:00603222470.026
hormone secretionGO:00468791150.026
actin filament based processGO:0030029860.026
Yeast
positive regulation of immunoglobulin productionGO:000263940.026
regulation of secretion by cellGO:19035302080.026
regulation of cellular extravasationGO:000269120.026
regulation of protein kinase activityGO:00458591050.026
negative regulation of neuron apoptotic processGO:0043524450.026
regulation of kinase activityGO:00435491170.026
regulation of hormone levelsGO:00108171870.026
negative regulation of programmed cell deathGO:00430691830.025
cellular component assemblyGO:00226073600.025
Yeast Rat
nucleic acid templated transcriptionGO:00976593790.025
response to hypoxiaGO:00016662310.025
salivary gland developmentGO:000743130.025
maintenance of locationGO:0051235170.025
multicellular organism reproductionGO:00325042330.024
blood vessel developmentGO:0001568690.024
positive regulation of cell deathGO:00109421840.024
positive regulation of isotype switching to igg isotypesGO:004830410.024
regulation of cell migrationGO:00303341280.024
central nervous system developmentGO:00074173110.024
positive regulation of cellular protein metabolic processGO:00322701670.024
response to mechanical stimulusGO:00096121340.024
regulation of phosphorus metabolic processGO:00511743490.024
cellular homeostasisGO:00197252520.024
regulation of cellular localizationGO:00603412630.023
regulation of neuron projection developmentGO:00109751610.023
gland developmentGO:00487321550.023
regulation of b cell mediated immunityGO:000271220.023
positive regulation of cell developmentGO:00107201760.023
positive regulation of multicellular organismal processGO:00512403870.023
positive regulation of cellular component organizationGO:00511302000.023
muscle contractionGO:0006936880.023
rna biosynthetic processGO:00327743800.022
negative regulation of insulin receptor signaling pathwayGO:0046627100.022
response to corticosteroidGO:00319602350.022
antigen receptor mediated signaling pathwayGO:005085110.022
regulation of ion transportGO:00432692450.022
hematopoietic or lymphoid organ developmentGO:0048534360.022
macromolecular complex assemblyGO:00650032730.022
Yeast Rat
regulation of transferase activityGO:00513381230.022
cytokine mediated signaling pathwayGO:0019221430.022
response to nutrient levelsGO:00316673700.022
regulation of homeostatic processGO:00328441010.022
actin filament bundle assemblyGO:0051017190.022
nucleobase containing small molecule metabolic processGO:00550863160.021
positive regulation of protein kinase activityGO:0045860730.021
cellular carbohydrate metabolic processGO:0044262720.021
regulation of immunoglobulin productionGO:000263740.021
locomotionGO:00400112370.021
positive regulation of cell projection organizationGO:00313461110.021
enzyme linked receptor protein signaling pathwayGO:00071671160.021
cell projection organizationGO:00300303020.021
biological adhesionGO:00226101100.021
protein transportGO:00150311320.021
muscle system processGO:00030121150.021
cellular response to endogenous stimulusGO:00714953770.021
cellular response to external stimulusGO:00714961180.021
neurotrophin trk receptor signaling pathwayGO:0048011100.021
negative regulation of homeostatic processGO:0032845470.021
purine containing compound metabolic processGO:00725212530.021
positive regulation of nucleic acid templated transcriptionGO:19035081970.020
b cell activation involved in immune responseGO:000231210.020
regulation of dna metabolic processGO:0051052600.020
regulation of cell proliferationGO:00421273590.020
negative regulation of neuron deathGO:1901215690.020
reproductionGO:00000032450.020
oxoacid metabolic processGO:00434362900.020
regulation of cell developmentGO:00602842630.020
regulation of locomotionGO:00400121480.020
regulation of sequestering of calcium ionGO:0051282260.020
cellular lipid metabolic processGO:00442552080.020
cellular response to hormone stimulusGO:00328702470.020
leukocyte activation involved in immune responseGO:0002366160.020
cytoskeleton organizationGO:00070101110.020
Yeast
axis specificationGO:000979840.020
brain developmentGO:00074202470.020
positive regulation of rna biosynthetic processGO:19026801970.020
positive regulation of transcription dna templatedGO:00458931970.020
positive regulation of macromolecule biosynthetic processGO:00105572470.019
negative regulation of signalingGO:00230571570.019
organic hydroxy compound metabolic processGO:19016151150.019
positive regulation of cell migrationGO:0030335960.019
nitrogen compound transportGO:00717052290.019
fc receptor mediated stimulatory signaling pathwayGO:000243130.019
regulation of calcium ion transport into cytosolGO:0010522250.019
regulation of system processGO:00440572080.019
response to toxic substanceGO:00096361330.019
small gtpase mediated signal transductionGO:0007264360.019
positive regulation of cellular amine metabolic processGO:003324030.019
regulation of protein metabolic processGO:00512462890.018
regulation of protein modification processGO:00313991940.018
olfactory learningGO:000835510.018
regulation of platelet activationGO:001054320.018
positive regulation of nervous system developmentGO:00519621780.018
regulation of b cell proliferationGO:003088860.018
response to other organismGO:00517072200.018
neuron apoptotic processGO:0051402880.018
anterior posterior pattern specificationGO:000995210.018
cellular response to oxygen containing compoundGO:19017013860.018
mononuclear cell proliferationGO:0032943290.018
cytokine productionGO:0001816610.018
intracellular transportGO:00469071850.018
organophosphate metabolic processGO:00196373700.017
positive regulation of humoral immune responseGO:000292220.017
motor neuron axon guidanceGO:000804510.017
cellular response to growth factor stimulusGO:00713631620.017
positive regulation of mapk cascadeGO:0043410920.017
regulation of response to stressGO:00801341260.017
regulation of nervous system developmentGO:00519602640.017
negative regulation of chronic inflammatory responseGO:000267720.017
positive regulation of intracellular protein transportGO:0090316200.017
regulation of cell adhesionGO:0030155520.017
protein autophosphorylationGO:0046777660.017
regulation of protein serine threonine kinase activityGO:0071900640.017
response to fatty acidGO:0070542650.017
single organism organelle organizationGO:19025891800.017
Yeast
cellular response to organonitrogen compoundGO:00714171970.017
reactive oxygen species metabolic processGO:0072593370.017
regulation of nucleic acid templated transcriptionGO:19035063800.017
vesicle mediated transportGO:00161921810.016
Yeast
positive regulation of neuron projection developmentGO:0010976990.016
positive regulation of smooth muscle cell migrationGO:0014911270.016
regulation of cellular component movementGO:00512701500.016
leukocyte cell cell adhesionGO:000715940.016
positive regulation of protein phosphorylationGO:00019341350.016
regulation of leukocyte proliferationGO:0070663260.016
insulin receptor signaling pathwayGO:0008286240.016
circulatory system developmentGO:00723591340.016
carboxylic acid metabolic processGO:00197522890.016
cell projection morphogenesisGO:00488581230.016
positive regulation of catalytic activityGO:00430851840.016
positive regulation of gamma delta t cell activationGO:004664510.016
cellular response to insulin stimulusGO:0032869810.016
neuron projection developmentGO:00311752730.016
cell morphogenesis involved in differentiationGO:00009041190.015
negative regulation of signal transductionGO:0009968830.015
negative regulation of cell communicationGO:00106481580.015
positive regulation of molecular functionGO:00440932300.015
anatomical structure formation involved in morphogenesisGO:0048646830.015
nuclear transportGO:0051169490.015
developmental process involved in reproductionGO:00030061590.015
positive regulation of cellular component movementGO:00512721020.015
regulation of mononuclear cell proliferationGO:0032944260.015
regulation of cellular protein metabolic processGO:00322682670.015
positive regulation of leukocyte activationGO:0002696300.015
leukocyte aggregationGO:007048610.015
glial cell differentiationGO:0010001650.015
cytokine metabolic processGO:004210760.015
leukocyte proliferationGO:0070661290.015
positive regulation of lymphocyte proliferationGO:0050671200.015
regulation of t cell proliferationGO:0042129170.015
actin filament bundle organizationGO:0061572190.015
regulation of isotype switchingGO:004519110.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.014
regulation of cellular ketone metabolic processGO:0010565270.014
reactive oxygen species biosynthetic processGO:190340980.014
regulation of rna biosynthetic processGO:20011413810.014
erythrocyte homeostasisGO:003410120.014
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.014
purine ribonucleoside catabolic processGO:00461301240.014
negative regulation of phosphate metabolic processGO:0045936800.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
reactive nitrogen species metabolic processGO:200105710.014
negative regulation of cell deathGO:00605482290.014
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124030.014
lipid metabolic processGO:00066292830.014
positive regulation of gene expressionGO:00106282440.014
actin cytoskeleton organizationGO:0030036730.014
Yeast
positive regulation of protein modification processGO:00314011420.014
positive regulation of immune effector processGO:0002699190.013
activation of protein kinase b activityGO:003214830.013
carbohydrate derivative metabolic processGO:19011353460.013
gamma delta t cell differentiationGO:004249210.013
dna metabolic processGO:0006259960.013
regulation of cell activationGO:0050865500.013
membrane organizationGO:0061024940.013
peptidyl tyrosine phosphorylationGO:0018108720.013
rna metabolic processGO:00160704060.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
negative regulation of sequestering of calcium ionGO:0051283250.013
regulation of cellular component organizationGO:00511283680.013
negative regulation of catalytic activityGO:00430861030.013
response to vitaminGO:00332731310.013
erk1 and erk2 cascadeGO:0070371480.013
phosphatidylinositol 3 kinase signalingGO:0014065140.013
positive regulation of myeloid cell differentiationGO:004563970.012
positive regulation of kinase activityGO:0033674770.012
positive regulation of nf kappab import into nucleusGO:004234620.012
mast cell chemotaxisGO:000255140.012
inflammatory responseGO:00069541500.012
positive regulation of secretionGO:00510471400.012
positive regulation of cellular component biogenesisGO:0044089550.012
mitotic spindle organizationGO:000705220.012
cell cycleGO:00070491010.012
gamete generationGO:00072761240.012
defense response to gram negative bacteriumGO:005082930.012
regulation of response to woundingGO:1903034690.012
heterotypic cell cell adhesionGO:003411320.012
positive regulation of leukocyte degranulationGO:004330240.012
signal releaseGO:00230611450.012
myoblast fusionGO:000752020.012
regulation of ion homeostasisGO:2000021630.012
positive regulation of fc receptor mediated stimulatory signaling pathwayGO:006036910.012
regulation of cell motilityGO:20001451310.012
cellular response to oxidative stressGO:0034599760.012
cellular response to peptideGO:19016531330.012
progesterone receptor signaling pathwayGO:005084710.012
peptide transportGO:0015833970.012
regulation of actin filament based processGO:0032970420.011
regulation of isotype switching to igg isotypesGO:004830210.011
response to peptide hormoneGO:00434342780.011
multicellular organismal homeostasisGO:0048871490.011
tube developmentGO:0035295890.011
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.011
regulation of cellular response to insulin stimulusGO:1900076160.011
lipid storageGO:001991510.011
defense response to gram positive bacteriumGO:005083020.011
negative regulation of macromolecule metabolic processGO:00106052600.011
embryonic pattern specificationGO:000988010.011
cell adhesionGO:00071551100.011
positive regulation of hydrolase activityGO:0051345860.011
negative regulation of cell proliferationGO:00082851190.011
negative regulation of apoptotic processGO:00430661810.011
syncytium formationGO:000694940.011
response to radiationGO:00093141370.011
positive regulation of leukocyte differentiationGO:1902107130.011
negative regulation of molecular functionGO:00440921330.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
peptidyl tyrosine modificationGO:0018212720.011
defense response to other organismGO:0098542170.011
cytosolic calcium ion transportGO:0060401390.011
positive regulation of cytokine productionGO:0001819420.011
negative regulation of cellular metabolic processGO:00313242810.011
t cell migrationGO:007267820.011
cellular response to abiotic stimulusGO:0071214850.011
spindle organizationGO:000705120.011
protein complex assemblyGO:00064612630.011
Yeast Rat
regulation of multicellular organismal developmentGO:20000263760.011
cardiovascular system developmentGO:00723581340.011
nucleoside phosphate metabolic processGO:00067532830.011
organelle organizationGO:00069962660.010
Yeast
macrophage activationGO:0042116150.010
regenerationGO:00310991630.010
lymphocyte activation involved in immune responseGO:000228530.010
response to peptideGO:19016522920.010
response to oxidative stressGO:00069791860.010
triglyceride homeostasisGO:007032820.010
positive regulation of transferase activityGO:0051347810.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
sexual reproductionGO:00199531480.010
ribonucleoside triphosphate metabolic processGO:00091991410.010
response to purine containing compoundGO:00140741260.010
regulation of cytokinesisGO:003246530.010
transcription dna templatedGO:00063513770.010
phospholipid metabolic processGO:0006644610.010
organic cyclic compound catabolic processGO:19013611750.010
ribose phosphate metabolic processGO:00196932350.010
regulation of neutrophil migrationGO:190262260.010
embryonic axis specificationGO:000057810.010
single organism cell adhesionGO:0098602460.010
alcohol metabolic processGO:0006066770.010

Sla disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
endocrine system diseaseDOID:2800.013
thyroid gland diseaseDOID:5000.013
congenital hypothyroidismDOID:005032800.013
disease of anatomical entityDOID:700.013
hypothyroidismDOID:145900.013