IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Ttc30b

tetratricopeptide repeat domain 30B

(Aliases: MGC188467)

Entrez: 499814
RGD: 1590784
UniProtKB: B2RYD6

Process Predictions
Disease Predictions

Ttc30b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular component assembly	GO:0022607	360	0.060
cellular component biogenesis	GO:0044085	368	0.057
reproductive process	GO:0022414	372	0.054
olfactory learning	GO:0008355	1	0.049
organelle organization	GO:0006996	266	0.046
ion transmembrane transport	GO:0034220	365	0.044
nucleosome organization	GO:0034728	1	0.040
reproduction	GO:0000003	245	0.039
single organism reproductive process	GO:0044702	297	0.037
transmembrane transport	GO:0055085	412	0.033
regulation of phosphorus metabolic process	GO:0051174	349	0.031
macromolecular complex subunit organization	GO:0043933	339	0.031
protein complex subunit organization	GO:0071822	302	0.030
organic acid metabolic process	GO:0006082	292	0.030
divalent inorganic cation homeostasis	GO:0072507	165	0.029
cation transport	GO:0006812	382	0.029
regulation of cellular component organization	GO:0051128	368	0.028
anatomical structure morphogenesis	GO:0009653	298	0.028
multicellular organism reproduction	GO:0032504	233	0.027
regulation of cellular amine metabolic process	GO:0033238	8	0.027
cell projection organization	GO:0030030	302	0.027
carboxylic acid metabolic process	GO:0019752	289	0.027
single organism catabolic process	GO:0044712	283	0.025
protein complex biogenesis	GO:0070271	263	0.025
cellular response to stress	GO:0033554	269	0.024
multi organism reproductive process	GO:0044703	262	0.023
single organism organelle organization	GO:1902589	180	0.023
regulation of cellular amino acid metabolic process	GO:0006521	2	0.022
cation transmembrane transport	GO:0098655	263	0.022
amine metabolic process	GO:0009308	38	0.022
cellular amine metabolic process	GO:0044106	38	0.022
catabolic process	GO:0009056	351	0.022
cellular ketone metabolic process	GO:0042180	51	0.022
multicellular organismal reproductive process	GO:0048609	233	0.022
dna packaging	GO:0006323	4	0.022
regulation of phosphorylation	GO:0042325	248	0.021
regulation of protein metabolic process	GO:0051246	289	0.021
regulation of phosphate metabolic process	GO:0019220	349	0.021
gliogenesis	GO:0042063	93	0.021
protein complex assembly	GO:0006461	263	0.021
small gtpase mediated signal transduction	GO:0007264	36	0.021
cellular amino acid metabolic process	GO:0006520	107	0.021
oxoacid metabolic process	GO:0043436	290	0.021
male mating behavior	GO:0060179	3	0.020
neuron differentiation	GO:0030182	368	0.019
regulation of cell proliferation	GO:0042127	359	0.019
inorganic ion transmembrane transport	GO:0098660	229	0.019
cellular response to oxygen containing compound	GO:1901701	386	0.019
intracellular signal transduction	GO:0035556	314	0.019
regulation of molecular function	GO:0065009	398	0.019
establishment of anatomical structure orientation	GO:0048560	1	0.019
macromolecular complex assembly	GO:0065003	273	0.019
regulation of cellular ketone metabolic process	GO:0010565	27	0.018
apoptotic process	GO:0006915	381	0.018
positive regulation of cellular amine metabolic process	GO:0033240	3	0.018
regulation of protein modification process	GO:0031399	194	0.018
protein oligomerization	GO:0051259	191	0.018
cellular catabolic process	GO:0044248	295	0.018
multi multicellular organism process	GO:0044706	138	0.018
programmed cell death	GO:0012501	392	0.018
central nervous system development	GO:0007417	311	0.017
cellular response to peptide	GO:1901653	133	0.017
organic substance catabolic process	GO:1901575	316	0.017
chromatin assembly or disassembly	GO:0006333	1	0.017
cellular response to nitrogen compound	GO:1901699	210	0.017
positive regulation of cellular biosynthetic process	GO:0031328	295	0.017
positive regulation of cellular protein metabolic process	GO:0032270	167	0.017
rna metabolic process	GO:0016070	406	0.017
metal ion transport	GO:0030001	289	0.017
intracellular transport	GO:0046907	185	0.017
regulation of protein phosphorylation	GO:0001932	183	0.017
oxidation reduction process	GO:0055114	304	0.017
neurological system process	GO:0050877	219	0.017
cellular homeostasis	GO:0019725	252	0.017
learning or memory	GO:0007611	90	0.017
response to peptide hormone	GO:0043434	278	0.017
positive regulation of molecular function	GO:0044093	230	0.017
rna biosynthetic process	GO:0032774	380	0.016
negative regulation of macromolecule metabolic process	GO:0010605	260	0.016
response to oxygen levels	GO:0070482	265	0.016
regulation of cell differentiation	GO:0045595	320	0.016
nucleic acid templated transcription	GO:0097659	379	0.016
single organism behavior	GO:0044708	130	0.015
protein phosphorylation	GO:0006468	345	0.015
negative regulation of metabolic process	GO:0009892	331	0.015
positive regulation of cellular component organization	GO:0051130	200	0.015
mapk cascade	GO:0000165	140	0.015
positive regulation of phosphorylation	GO:0042327	177	0.015
regulation of cellular protein metabolic process	GO:0032268	267	0.015
regulation of cellular localization	GO:0060341	263	0.015
cellular response to peptide hormone stimulus	GO:0071375	120	0.015
positive regulation of protein metabolic process	GO:0051247	178	0.015
sexual reproduction	GO:0019953	148	0.015
response to peptide	GO:1901652	292	0.014
positive regulation of multicellular organismal process	GO:0051240	387	0.014
carbohydrate derivative metabolic process	GO:1901135	346	0.014
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.014
neuron projection development	GO:0031175	273	0.014
positive regulation of developmental process	GO:0051094	283	0.014
cellular component movement	GO:0006928	248	0.014
positive regulation of phosphorus metabolic process	GO:0010562	262	0.014
regulation of cell development	GO:0060284	263	0.014
regulation of cell projection organization	GO:0031344	175	0.014
calcium ion homeostasis	GO:0055074	162	0.014
regulation of catalytic activity	GO:0050790	304	0.014
inorganic cation transmembrane transport	GO:0098662	202	0.014
response to decreased oxygen levels	GO:0036293	237	0.014
regulation of neurogenesis	GO:0050767	247	0.014
locomotion	GO:0040011	237	0.014
chemical homeostasis	GO:0048878	292	0.013
olfactory behavior	GO:0042048	2	0.013
positive regulation of cell communication	GO:0010647	271	0.013
cognition	GO:0050890	92	0.013
cell projection morphogenesis	GO:0048858	123	0.013
macromolecule localization	GO:0033036	252	0.013
dna metabolic process	GO:0006259	96	0.013
regulation of transcription dna templated	GO:0006355	374	0.013
cellular chemical homeostasis	GO:0055082	247	0.013
regulation of intracellular signal transduction	GO:1902531	218	0.013
male gamete generation	GO:0048232	99	0.013
behavior	GO:0007610	205	0.012
cellular response to hormone stimulus	GO:0032870	247	0.012
metal ion homeostasis	GO:0055065	186	0.012
cellular response to endogenous stimulus	GO:0071495	377	0.012
cellular response to organonitrogen compound	GO:0071417	197	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.012
transcription dna templated	GO:0006351	377	0.012
regulation of membrane potential	GO:0042391	110	0.012
ion homeostasis	GO:0050801	212	0.012
negative regulation of multicellular organismal process	GO:0051241	203	0.012
negative regulation of apoptotic process	GO:0043066	181	0.012
positive regulation of protein modification process	GO:0031401	142	0.012
positive regulation of gene expression	GO:0010628	244	0.012
glycosyl compound metabolic process	GO:1901657	182	0.012
spermatogenesis	GO:0007283	99	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.012
anion transport	GO:0006820	178	0.012
cellular calcium ion homeostasis	GO:0006874	160	0.012
regulation of nucleic acid templated transcription	GO:1903506	380	0.012
negative regulation of gene expression	GO:0010629	199	0.011
neuron development	GO:0048666	286	0.011
negative regulation of transport	GO:0051051	136	0.011
positive regulation of phosphate metabolic process	GO:0045937	262	0.011
regulation of protein kinase activity	GO:0045859	105	0.011
negative regulation of programmed cell death	GO:0043069	183	0.011
aging	GO:0007568	241	0.011
regulation of apoptotic process	GO:0042981	335	0.011
negative regulation of molecular function	GO:0044092	133	0.011
positive regulation of biosynthetic process	GO:0009891	319	0.011
chromosome segregation	GO:0007059	2	0.011
cell cycle checkpoint	GO:0000075	2	0.011
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.011
cytoplasmic transport	GO:0016482	115	0.011
response to inorganic substance	GO:0010035	377	0.011
regulation of rna metabolic process	GO:0051252	391	0.011
ras protein signal transduction	GO:0007265	29	0.011
regulation of transferase activity	GO:0051338	123	0.011
negative regulation of cell communication	GO:0010648	158	0.011
regulation of ion transport	GO:0043269	245	0.011
divalent inorganic cation transport	GO:0072511	134	0.011
divalent metal ion transport	GO:0070838	132	0.011
nucleobase containing small molecule metabolic process	GO:0055086	316	0.011
regulation of neuron death	GO:1901214	115	0.011
response to acid chemical	GO:0001101	222	0.011
regulation of neuron differentiation	GO:0045664	208	0.011
fertilization	GO:0009566	3	0.010
regulation of nervous system development	GO:0051960	264	0.010
cation homeostasis	GO:0055080	195	0.010
synaptic transmission	GO:0007268	235	0.010
rho protein signal transduction	GO:0007266	11	0.010
response to metal ion	GO:0010038	253	0.010
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.010
organophosphate biosynthetic process	GO:0090407	143	0.010
positive regulation of signal transduction	GO:0009967	175	0.010
single fertilization	GO:0007338	3	0.010
organophosphate metabolic process	GO:0019637	370	0.010
developmental process involved in reproduction	GO:0003006	159	0.010
defense response to gram negative bacterium	GO:0050829	3	0.010
purine nucleotide metabolic process	GO:0006163	229	0.010
cellular cation homeostasis	GO:0030003	180	0.010

Ttc30b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.036
disease of anatomical entity	DOID:7	0.036
sensory system disease	DOID:0050155	0.017
eye and adnexa disease	DOID:1492	0.017
disease of cellular proliferation	DOID:14566	0.014
eye disease	DOID:5614	0.014
muscular disease	DOID:0080000	0.011
muscle tissue disease	DOID:66	0.011
musculoskeletal system disease	DOID:17	0.011

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