Rattus norvegicus

61 known processes

Gjb2

gap junction protein, beta 2

(Aliases: Cx26,CXN-26,MGC93804)

Gjb2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to metal ionGO:00100382530.227
organic acid biosynthetic processGO:0016053830.214
nitrogen compound transportGO:00717052290.195
Rat
monocarboxylic acid transportGO:0015718520.183
transmembrane transportGO:00550854120.183
cellular response to oxygen containing compoundGO:19017013860.182
Rat
response to inorganic substanceGO:00100353770.163
Rat
organic anion transportGO:00157111320.157
Rat
anion transportGO:00068201780.150
Rat
carboxylic acid transportGO:00469421150.143
response to transition metal nanoparticleGO:19902671220.131
response to retinoic acidGO:0032526630.130
cellular response to lipidGO:00713962010.128
ion transmembrane transportGO:00342203650.125
response to nutrient levelsGO:00316673700.121
amino acid transmembrane transportGO:0003333330.118
organic acid transportGO:00158491160.116
response to campGO:0051591910.111
secretionGO:00469033070.111
Rat
organic acid metabolic processGO:00060822920.101
choline transportGO:001587140.099
cellular response to organonitrogen compoundGO:00714171970.097
anion transmembrane transportGO:0098656770.097
reproductive processGO:00224143720.096
response to estrogenGO:00436272320.095
carboxylic acid biosynthetic processGO:0046394830.093
response to organophosphorusGO:00466831020.093
response to nutrientGO:00075842480.091
protein complex assemblyGO:00064612630.090
Rat
response to purine containing compoundGO:00140741260.088
response to extracellular stimulusGO:00099913800.087
central nervous system developmentGO:00074173110.087
cellular component biogenesisGO:00440853680.087
Rat
amino acid transportGO:0006865700.085
response to acid chemicalGO:00011012220.085
carboxylic acid metabolic processGO:00197522890.084
response to toxic substanceGO:00096361330.083
oxoacid metabolic processGO:00434362900.079
protein oligomerizationGO:00512591910.078
Rat
response to corticosteroidGO:00319602350.077
cellular response to endogenous stimulusGO:00714953770.075
macromolecular complex subunit organizationGO:00439333390.073
Rat
protein complex biogenesisGO:00702712630.072
Rat
protein complex subunit organizationGO:00718223020.069
Rat
tissue developmentGO:00098882520.067
response to carbohydrateGO:00097431830.066
Rat
regulation of multicellular organismal developmentGO:20000263760.065
Rat
regulation of cell proliferationGO:00421273590.063
Rat
protein homooligomerizationGO:0051260910.063
macromolecule localizationGO:00330362520.061
single organism reproductive processGO:00447022970.060
lipid biosynthetic processGO:00086101280.059
reproductionGO:00000032450.059
cation transportGO:00068123820.058
Rat
multicellular organismal reproductive processGO:00486092330.057
response to biotic stimulusGO:00096072260.057
Rat
cellular response to peptideGO:19016531330.053
multi organism reproductive processGO:00447032620.053
cellular response to nitrogen compoundGO:19016992100.051
response to glucocorticoidGO:00513842230.050
regulation of secretionGO:00510462240.050
Rat
lipid transportGO:0006869610.050
cellular amino acid biosynthetic processGO:0008652320.049
gamete generationGO:00072761240.049
response to estradiolGO:00323551640.048
kidney developmentGO:0001822670.047
organic hydroxy compound transportGO:0015850770.047
multicellular organism reproductionGO:00325042330.046
cellular response to organic cyclic compoundGO:00714072020.046
negative regulation of multicellular organismal processGO:00512412030.046
Rat
response to woundingGO:00096112540.045
Rat
cofactor metabolic processGO:0051186950.045
behaviorGO:00076102050.045
Rat
negative regulation of nervous system developmentGO:0051961790.045
regulation of hormone levelsGO:00108171870.044
Rat
macromolecular complex assemblyGO:00650032730.044
Rat
head developmentGO:00603222470.043
programmed cell deathGO:00125013920.043
Rat
sexual reproductionGO:00199531480.043
cellular amino acid metabolic processGO:00065201070.042
catabolic processGO:00090563510.042
Rat
response to hypoxiaGO:00016662310.041
cellular ketone metabolic processGO:0042180510.041
anatomical structure morphogenesisGO:00096532980.040
Rat
cellular component assemblyGO:00226073600.040
Rat
regulation of cellular localizationGO:00603412630.040
Rat
negative regulation of cell developmentGO:0010721820.039
response to oxygen levelsGO:00704822650.039
positive regulation of secretionGO:00510471400.039
Rat
neuron differentiationGO:00301823680.039
Rat
defense responseGO:00069521940.039
Rat
response to peptide hormoneGO:00434342780.038
Rat
cell cell signalingGO:00072673350.038
Rat
response to vitaminGO:00332731310.038
organelle organizationGO:00069962660.038
positive regulation of transportGO:00510502450.038
Rat
regulation of programmed cell deathGO:00430673410.038
response to hexoseGO:00097461440.037
Rat
single organism catabolic processGO:00447122830.037
positive regulation of cell proliferationGO:00082842490.036
positive regulation of phosphorus metabolic processGO:00105622620.036
learning or memoryGO:0007611900.036
wound healingGO:00420601220.036
Rat
nucleobase containing small molecule metabolic processGO:00550863160.036
monocarboxylic acid metabolic processGO:00327871520.035
brain developmentGO:00074202470.034
negative regulation of metabolic processGO:00098923310.034
Rat
neurological system processGO:00508772190.033
Rat
negative regulation of developmental processGO:00510931250.033
Rat
small molecule biosynthetic processGO:00442831240.033
response to lipopolysaccharideGO:00324961910.032
Rat
cellular homeostasisGO:00197252520.032
Rat
liver developmentGO:0001889900.032
negative regulation of programmed cell deathGO:00430691830.032
urogenital system developmentGO:0001655780.032
intracellular signal transductionGO:00355563140.032
negative regulation of macromolecule metabolic processGO:00106052600.031
Rat
response to ethanolGO:00454711620.031
response to decreased oxygen levelsGO:00362932370.031
cellular amine metabolic processGO:0044106380.031
cellular response to peptide hormone stimulusGO:00713751200.031
regulation of cell differentiationGO:00455953200.030
single organism biosynthetic processGO:00447113420.030
response to monosaccharideGO:00342841590.030
Rat
negative regulation of cell differentiationGO:0045596990.030
response to alkaloidGO:00432791320.030
cellular lipid metabolic processGO:00442552080.030
regulation of nervous system developmentGO:00519602640.029
cellular hormone metabolic processGO:0034754490.029
neuron projection developmentGO:00311752730.029
Rat
cation transmembrane transportGO:00986552630.029
cellular catabolic processGO:00442482950.028
cellular modified amino acid metabolic processGO:0006575610.028
renal system developmentGO:0072001670.028
negative regulation of neuron differentiationGO:0045665620.028
drug transmembrane transportGO:0006855130.028
oxidation reduction processGO:00551143040.028
regulation of body fluid levelsGO:0050878900.028
Rat
positive regulation of immunoglobulin productionGO:000263940.028
regulation of apoptotic processGO:00429813350.028
agingGO:00075682410.028
Rat
response to molecule of bacterial originGO:00022371940.027
Rat
regulation of molecular functionGO:00650093980.027
negative regulation of cell communicationGO:00106481580.027
cellular chemical homeostasisGO:00550822470.027
Rat
developmental growthGO:00485891000.026
Rat
response to peptideGO:19016522920.026
Rat
cellular response to hormone stimulusGO:00328702470.026
response to nicotineGO:0035094510.026
negative regulation of signalingGO:00230571570.026
neurotransmitter uptakeGO:000150430.026
positive regulation of amino acid transportGO:0051957130.026
organic substance catabolic processGO:19015753160.025
Rat
acid secretionGO:0046717480.025
glycerol transportGO:001579320.025
regulation of cellular component organizationGO:00511283680.025
Rat
heterocycle catabolic processGO:00467001670.025
organophosphate catabolic processGO:00464341480.024
amide transportGO:00428861050.024
Rat
aromatic compound catabolic processGO:00194391680.024
response to radiationGO:00093141370.024
regenerationGO:00310991630.024
organic cation transportGO:0015695110.024
positive regulation of protein metabolic processGO:00512471780.024
Rat
regulation of protein metabolic processGO:00512462890.024
Rat
reproductive system developmentGO:00614581280.023
epithelium developmentGO:0060429960.023
Rat
cell projection morphogenesisGO:00488581230.023
Rat
positive regulation of gamma aminobutyric acid secretionGO:001405440.023
cellular response to molecule of bacterial originGO:0071219560.023
lipid localizationGO:0010876620.023
organophosphate metabolic processGO:00196373700.022
signal releaseGO:00230611450.022
Rat
oligopeptide transportGO:000685740.022
positive regulation of cellular protein metabolic processGO:00322701670.022
peptide biosynthetic processGO:004304330.022
response to ketoneGO:19016541820.022
regulation of secretion by cellGO:19035302080.021
Rat
regulation of protein transportGO:0051223680.021
regulation of phosphorus metabolic processGO:00511743490.021
protein phosphorylationGO:00064683450.021
nucleoside phosphate metabolic processGO:00067532830.021
cellular response to acid chemicalGO:0071229750.021
positive regulation of phosphate metabolic processGO:00459372620.021
regulation of cellular ketone metabolic processGO:0010565270.021
lipid metabolic processGO:00066292830.021
chemical homeostasisGO:00488782920.021
Rat
regulation of neuron differentiationGO:00456642080.021
biological adhesionGO:00226101100.020
cellular component movementGO:00069282480.020
response to other organismGO:00517072200.020
Rat
carbohydrate derivative metabolic processGO:19011353460.020
regulation of intracellular signal transductionGO:19025312180.020
regulation of catalytic activityGO:00507903040.020
regulation of phosphate metabolic processGO:00192203490.020
response to growth factorGO:00708481890.020
regulation of membrane potentialGO:00423911100.020
nucleotide metabolic processGO:00091172790.020
regulation of cellular amino acid metabolic processGO:000652120.020
response to cytokineGO:00340972150.019
spermatogenesisGO:0007283990.019
regulation of signal transductionGO:00099663180.019
gastrulationGO:000736920.019
monocarboxylic acid biosynthetic processGO:0072330480.019
positive regulation of phosphorylationGO:00423271770.019
regulation of rna biosynthetic processGO:20011413810.019
response to glucoseGO:00097491360.019
Rat
response to external biotic stimulusGO:00432072210.019
Rat
regulation of kinase activityGO:00435491170.019
regulation of anatomical structure sizeGO:00900661350.019
Rat
organic cyclic compound catabolic processGO:19013611750.019
negative regulation of nitrogen compound metabolic processGO:00511721610.018
Rat
negative regulation of cellular metabolic processGO:00313242810.018
Rat
peptide transportGO:0015833970.018
Rat
amine metabolic processGO:0009308380.018
negative regulation of cellular biosynthetic processGO:00313271610.018
Rat
circulatory system processGO:00030131830.018
Rat
protein localizationGO:00081041910.018
cell activationGO:0001775970.018
cellular response to insulin stimulusGO:0032869810.018
steroid metabolic processGO:0008202730.018
hepaticobiliary system developmentGO:0061008900.017
response to ionizing radiationGO:0010212590.017
multi multicellular organism processGO:00447061380.017
cellular response to cgmpGO:007132120.017
protein transportGO:00150311320.017
tube developmentGO:0035295890.017
gliogenesisGO:0042063930.017
positive regulation of ion transportGO:0043270940.017
mesoderm developmentGO:000749820.017
negative regulation of rna metabolic processGO:00512531230.017
coenzyme metabolic processGO:0006732860.017
regulation of neurogenesisGO:00507672470.017
fatty acid biosynthetic processGO:0006633330.017
rhythmic processGO:00485111560.016
apoptotic processGO:00069153810.016
Rat
purine nucleotide metabolic processGO:00061632290.016
regulation of cellular protein metabolic processGO:00322682670.016
negative regulation of neurogenesisGO:0050768780.016
regulation of cell adhesionGO:0030155520.016
cellular response to lipopolysaccharideGO:0071222550.016
modified amino acid transportGO:0072337120.016
glycosyl compound metabolic processGO:19016571820.016
organonitrogen compound biosynthetic processGO:19015661670.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
Rat
coagulationGO:0050817280.016
male gamete generationGO:0048232990.016
negative regulation of cell deathGO:00605482290.016
cellular response to growth factor stimulusGO:00713631620.016
positive regulation of molecular functionGO:00440932300.016
limb morphogenesisGO:003510840.016
regulation of cell developmentGO:00602842630.016
positive regulation of cellular amine metabolic processGO:003324030.016
cell projection organizationGO:00300303020.016
Rat
blood circulationGO:00080151830.016
Rat
negative regulation of response to stimulusGO:00485851550.015
Rat
embryonic appendage morphogenesisGO:003511340.015
insecticide metabolic processGO:001714340.015
purine ribonucleotide metabolic processGO:00091502270.015
eye morphogenesisGO:004859240.015
cellular response to abiotic stimulusGO:0071214850.015
Rat
purine containing compound metabolic processGO:00725212530.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.015
regulation of blood vessel sizeGO:0050880890.015
Rat
single organism behaviorGO:00447081300.015
Rat
ribonucleotide metabolic processGO:00092592310.015
cellular nitrogen compound catabolic processGO:00442701630.015
negative regulation of transcription dna templatedGO:00458921160.015
positive regulation of apoptotic processGO:00430651540.015
positive regulation of cell differentiationGO:00455972170.014
rna biosynthetic processGO:00327743800.014
small molecule catabolic processGO:0044282590.014
vitamin transportGO:0051180140.014
ribose phosphate metabolic processGO:00196932350.014
transcription dna templatedGO:00063513770.014
single organism organelle organizationGO:19025891800.014
negative regulation of gene expressionGO:00106291990.014
glial cell differentiationGO:0010001650.014
ras protein signal transductionGO:0007265290.014
cell adhesionGO:00071551100.014
reproductive structure developmentGO:00486081280.014
proteolysisGO:00065081750.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
cognitionGO:0050890920.014
intracellular transportGO:00469071850.014
neurotransmitter transportGO:0006836420.014
tripeptide transportGO:004293920.014
cellular component morphogenesisGO:00329891550.014
Rat
regulation of system processGO:00440572080.014
Rat
regulation of immunoglobulin productionGO:000263740.014
regulation of cellular amine metabolic processGO:003323880.014
synaptic transmissionGO:00072682350.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
positive regulation of protein phosphorylationGO:00019341350.014
nucleobase containing compound catabolic processGO:00346551520.014
regulation of transcription dna templatedGO:00063553740.014
regulation of ion transportGO:00432692450.014
Rat
regulation of rna metabolic processGO:00512523910.014
defense response to gram negative bacteriumGO:005082930.014
inorganic cation transmembrane transportGO:00986622020.014
response to bacteriumGO:00096172000.014
Rat
single organismal cell cell adhesionGO:0016337420.014
regulation of response to external stimulusGO:00321011060.014
Rat
regulation of transferase activityGO:00513381230.014
negative regulation of protein metabolic processGO:00512481140.014
regulation of response to woundingGO:1903034690.013
Rat
dopamine transportGO:0015872180.013
positive regulation of response to stimulusGO:00485842850.013
Rat
purine ribonucleoside metabolic processGO:00461281680.013
regulation of cell projection organizationGO:00313441750.013
neural crest cell differentiationGO:001403320.013
amide biosynthetic processGO:0043604100.013
muscle tissue developmentGO:0060537580.013
Rat
positive regulation of programmed cell deathGO:00430681570.013
c21 steroid hormone biosynthetic processGO:0006700100.013
positive regulation of cell growthGO:0030307440.013
positive regulation of catalytic activityGO:00430851840.013
regulation of hydrolase activityGO:00513361430.013
neuron neuron synaptic transmissionGO:0007270600.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
Rat
regulation of cell growthGO:0001558850.013
organ regenerationGO:00311001010.013
organonitrogen compound catabolic processGO:19015651790.013
positive regulation of protein modification processGO:00314011420.013
cellular response to hexose stimulusGO:0071331650.013
Rat
regulation of catabolic processGO:00098941130.013
Rat
cellular modified amino acid biosynthetic processGO:0042398180.013
response to mercury ionGO:0046689150.013
metal ion transportGO:00300012890.013
Rat
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.013
cell part morphogenesisGO:00329901230.012
Rat
regulation of response to stressGO:00801341260.012
Rat
cellular hyperosmotic responseGO:007147440.012
developmental process involved in reproductionGO:00030061590.012
negative regulation of synaptic transmission dopaminergicGO:003222740.012
positive regulation of cell communicationGO:00106472710.012
Rat
reactive oxygen species biosynthetic processGO:190340980.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
anterior posterior pattern specificationGO:000995210.012
response to antibioticGO:0046677390.012
homeostatic processGO:00425923310.012
Rat
cell proliferation in external granule layerGO:002192410.012
negative regulation of molecular functionGO:00440921330.012
positive regulation of nitrogen compound metabolic processGO:00511733340.012
nucleoside metabolic processGO:00091161790.012
response to lead ionGO:0010288330.012
small gtpase mediated signal transductionGO:0007264360.012
cell morphogenesisGO:00009021420.012
Rat
positive regulation of isotype switchingGO:004583010.012
cell migrationGO:00164771970.012
cell type specific apoptotic processGO:00972851340.012
cellular macromolecule localizationGO:00707271220.012
axis specificationGO:000979840.012
positive regulation of immune system processGO:0002684900.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
Rat
regulation of canonical wnt signaling pathwayGO:006082840.012
porphyrin containing compound metabolic processGO:000677880.012
response to testosteroneGO:0033574550.012
establishment of protein localizationGO:00451841410.012
regulation of protein modification processGO:00313991940.012
response to mechanical stimulusGO:00096121340.012
Rat
response to cgmpGO:007030530.012
cell motilityGO:00488702020.012
regulation of immunoglobulin secretionGO:005102310.012
purine nucleoside metabolic processGO:00422781690.012
memoryGO:0007613540.011
reactive oxygen species metabolic processGO:0072593370.011
non canonical wnt signaling pathwayGO:003556730.011
cellular response to external stimulusGO:00714961180.011
Rat
t cell activationGO:0042110290.011
regulation of immune system processGO:00026821230.011
cellular response to stressGO:00335542690.011
rna metabolic processGO:00160704060.011
positive regulation of cell deathGO:00109421840.011
purine nucleotide catabolic processGO:00061951360.011
bile acid and bile salt transportGO:0015721120.011
glial cell developmentGO:0021782190.011
positive regulation of developmental processGO:00510942830.011
locomotionGO:00400112370.011
regulation of protein phosphorylationGO:00019321830.011
cofactor biosynthetic processGO:0051188280.011
cellular response to steroid hormone stimulusGO:0071383930.011
organ morphogenesisGO:0009887750.011
regulation of tube sizeGO:0035150890.011
Rat
embryo developmentGO:0009790490.011
Rat
neuron developmentGO:00486662860.011
Rat
hormone metabolic processGO:0042445690.011
nucleoside phosphate catabolic processGO:19012921400.011
regulation of peptide secretionGO:0002791820.011
Rat
alpha amino acid metabolic processGO:1901605710.011
positive regulation of secretion by cellGO:19035321280.011
Rat
hormone transportGO:00099141210.011
Rat
b cell differentiationGO:003018320.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
negative regulation of cellular protein metabolic processGO:00322691060.011
negative regulation of transportGO:00510511360.011
canalicular bile acid transportGO:001572250.011
regulation of synaptic plasticityGO:0048167700.011
negative regulation of apoptotic processGO:00430661810.011
regulation of cellular component movementGO:00512701500.011
regulation of developmental growthGO:0048638450.010
Rat
fatty acid metabolic processGO:0006631990.010
cell growthGO:00160491040.010
immune system processGO:00023762040.010
embryonic limb morphogenesisGO:003032640.010
gland developmentGO:00487321550.010
positive regulation of intracellular signal transductionGO:19025331380.010
purine containing compound catabolic processGO:00725231380.010
glutathione transportGO:003463520.010
response to oxidative stressGO:00069791860.010
negative regulation of biosynthetic processGO:00098901680.010
Rat
dna metabolic processGO:0006259960.010
Rat
axon developmentGO:0061564960.010
single organism cellular localizationGO:19025801020.010
alcohol metabolic processGO:0006066770.010
astrocyte developmentGO:001400240.010

Gjb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.027
disease of anatomical entityDOID:700.023
Human
nervous system diseaseDOID:86300.023
Human
inherited metabolic disorderDOID:65500.013
gastrointestinal system diseaseDOID:7700.011
central nervous system diseaseDOID:33100.011