Rattus norvegicus

0 known processes

Klrk1

killer cell lectin-like receptor subfamily K, member 1

(Aliases: NKG2D,Nkrp2)

Klrk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of immune response to tumor cellGO:000283820.358
Rat
regulation of immune response to tumor cellGO:000283730.353
Rat
leukocyte activationGO:0045321760.266
Mouse Rat
natural killer cell mediated immune response to tumor cellGO:000242310.243
Rat
regulation of rna biosynthetic processGO:20011413810.209
positive regulation of phosphate metabolic processGO:00459372620.181
negative regulation of response to tumor cellGO:000283520.177
Rat
regulation of cell developmentGO:00602842630.155
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.154
Rat
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.136
intracellular signal transductionGO:00355563140.129
regulation of rna metabolic processGO:00512523910.127
response to inorganic substanceGO:00100353770.123
Rat
immune responseGO:00069551040.116
Human Mouse Rat
nucleic acid templated transcriptionGO:00976593790.112
positive regulation of macromolecule biosynthetic processGO:00105572470.111
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285910.106
Rat
regulation of cellular localizationGO:00603412630.103
positive regulation of cell communicationGO:00106472710.102
innate immune responseGO:0045087350.100
Human Mouse Rat
rna metabolic processGO:00160704060.089
inflammatory responseGO:00069541500.086
Rat
regulation of nucleic acid templated transcriptionGO:19035063800.085
chemotaxisGO:0006935660.079
transcription dna templatedGO:00063513770.078
nitrogen compound transportGO:00717052290.076
regulation of secretionGO:00510462240.076
regulation of neurogenesisGO:00507672470.075
regulation of signal transductionGO:00099663180.075
cellular divalent inorganic cation homeostasisGO:00725031620.075
response to external biotic stimulusGO:00432072210.071
Mouse
cytosolic calcium ion homeostasisGO:00514801400.069
positive regulation of nervous system developmentGO:00519621780.068
positive regulation of neurogenesisGO:00507691650.068
regulation of molecular functionGO:00650093980.067
regulation of immune system processGO:00026821230.067
Human Mouse Rat
regulation of intracellular signal transductionGO:19025312180.066
regulation of cell differentiationGO:00455953200.063
cellular response to tumor necrosis factorGO:0071356460.063
response to cytokineGO:00340972150.061
positive regulation of cellular amine metabolic processGO:003324030.059
blood circulationGO:00080151830.059
metal ion transportGO:00300012890.058
positive regulation of cellular biosynthetic processGO:00313282950.057
Mouse
regulation of response to tumor cellGO:000283430.057
Rat
regulation of secretion by cellGO:19035302080.056
peptidyl amino acid modificationGO:00181931260.055
immune response to tumor cellGO:000241830.055
Rat
response to tumor cellGO:000234740.053
Rat
cellular response to cytokine stimulusGO:00713451270.053
negative regulation of macromolecule metabolic processGO:00106052600.051
secretionGO:00469033070.051
positive regulation of rna biosynthetic processGO:19026801970.049
positive regulation of intracellular signal transductionGO:19025331380.049
regulation of cellular amine metabolic processGO:003323880.048
anatomical structure morphogenesisGO:00096532980.048
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.047
Rat
regulation of cellular component organizationGO:00511283680.047
amine metabolic processGO:0009308380.047
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.046
Rat
peptidyl tyrosine phosphorylationGO:0018108720.046
positive regulation of neuron differentiationGO:00456661260.046
striated muscle contractionGO:0006941440.046
divalent metal ion transportGO:00708381320.045
cellular amine metabolic processGO:0044106380.045
regulation of protein phosphorylationGO:00019321830.044
negative regulation of natural killer cell mediated immunityGO:000271640.044
Rat
calcium ion homeostasisGO:00550741620.044
neuron differentiationGO:00301823680.044
secretion by cellGO:00329402480.043
regulation of phosphorus metabolic processGO:00511743490.043
signal releaseGO:00230611450.043
peptidyl tyrosine modificationGO:0018212720.043
regulation of ion transportGO:00432692450.042
protein phosphorylationGO:00064683450.042
negative regulation of nucleobase containing compound metabolic processGO:00459341530.042
positive regulation of mapk cascadeGO:0043410920.042
carbohydrate derivative metabolic processGO:19011353460.040
positive regulation of nitrogen compound metabolic processGO:00511733340.040
Mouse
circulatory system processGO:00030131830.039
lymphocyte activationGO:0046649430.039
Mouse Rat
positive regulation of transcription dna templatedGO:00458931970.039
endoplasmic reticulum to cytosol transportGO:190351340.038
positive regulation of signal transductionGO:00099671750.038
cellular amino acid metabolic processGO:00065201070.037
regulation of cellular amino acid metabolic processGO:000652120.037
response to purine containing compoundGO:00140741260.037
taxisGO:0042330670.037
positive regulation of nucleic acid templated transcriptionGO:19035081970.037
chemical homeostasisGO:00488782920.037
cellular metal ion homeostasisGO:00068751720.036
cell projection morphogenesisGO:00488581230.036
negative regulation of immune system processGO:0002683390.036
Rat
response to campGO:0051591910.036
positive regulation of gene expressionGO:00106282440.036
positive regulation of molecular functionGO:00440932300.035
positive regulation of biosynthetic processGO:00098913190.035
Mouse
rna biosynthetic processGO:00327743800.035
negative regulation of rna metabolic processGO:00512531230.035
jak stat cascadeGO:0007259260.035
negative regulation of gene expressionGO:00106291990.035
cellular homeostasisGO:00197252520.035
positive regulation of cell proliferationGO:00082842490.035
positive regulation of nucleobase containing compound metabolic processGO:00459353190.034
negative regulation of chronic inflammatory responseGO:000267720.034
intracellular transportGO:00469071850.034
positive regulation of cell developmentGO:00107201760.033
acute inflammatory responseGO:0002526580.033
salivary gland developmentGO:000743130.033
regulation of nervous system developmentGO:00519602640.033
regulation of phosphorylationGO:00423252480.033
heart contractionGO:0060047570.032
negative regulation of nucleic acid templated transcriptionGO:19035071170.032
regulation of necroptotic processGO:006054420.032
immune system processGO:00023762040.032
Human Mouse Rat
synaptic transmissionGO:00072682350.032
eosinophil chemotaxisGO:004824530.032
cytoplasmic transportGO:00164821150.031
neuron developmentGO:00486662860.031
positive regulation of cytosolic calcium ion concentrationGO:00072041220.030
fever generationGO:000166090.030
response to organophosphorusGO:00466831020.030
positive regulation of response to stimulusGO:00485842850.030
Human Mouse
t cell activationGO:0042110290.030
cellular chemical homeostasisGO:00550822470.029
positive regulation of signalingGO:00230562700.029
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.029
negative regulation of macromolecule biosynthetic processGO:00105581480.029
eosinophil migrationGO:007267730.029
regulation of phosphate metabolic processGO:00192203490.029
single organism catabolic processGO:00447122830.029
circulatory system developmentGO:00723591340.028
hormone secretionGO:00468791150.028
second messenger mediated signalingGO:0019932510.028
nucleoside phosphate metabolic processGO:00067532830.028
positive regulation of rna metabolic processGO:00512542030.028
purine ribonucleotide catabolic processGO:00091541360.027
response to ethanolGO:00454711620.027
positive regulation of phosphorylationGO:00423271770.027
peptide transportGO:0015833970.027
regulation of protein modification processGO:00313991940.027
positive regulation of cellular component organizationGO:00511302000.027
cellular catabolic processGO:00442482950.027
transcription from rna polymerase ii promoterGO:00063662520.026
programmed cell deathGO:00125013920.026
neuron deathGO:00709971270.026
ribonucleotide catabolic processGO:00092611360.026
regulation of locomotionGO:00400121480.026
positive regulation of immune system processGO:0002684900.025
Human Mouse
regulation of cellular ketone metabolic processGO:0010565270.025
response to radiationGO:00093141370.025
regulation of multicellular organismal developmentGO:20000263760.025
immune system developmentGO:0002520410.025
negative regulation of metabolic processGO:00098923310.025
purine containing compound catabolic processGO:00725231380.025
behaviorGO:00076102050.025
negative regulation of rna biosynthetic processGO:19026791180.025
regulation of lymphocyte migrationGO:200040110.025
regulation of neuron deathGO:19012141150.025
negative regulation of nitrogen compound metabolic processGO:00511721610.025
purine nucleotide metabolic processGO:00061632290.024
negative regulation of innate immune responseGO:004582440.024
Rat
response to metal ionGO:00100382530.024
positive regulation of protein modification processGO:00314011420.024
regulation of anatomical structure morphogenesisGO:00226031410.024
organic substance catabolic processGO:19015753160.024
regulation of synaptic transmissionGO:00508041410.024
lymphocyte migrationGO:007267630.024
response to peptideGO:19016522920.024
response to nutrient levelsGO:00316673700.024
cardiovascular system developmentGO:00723581340.023
t cell proliferationGO:0042098190.023
single organism intracellular transportGO:19025821660.023
ras protein signal transductionGO:0007265290.023
cellular ketone metabolic processGO:0042180510.023
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.023
immune effector processGO:0002252530.023
Human Mouse Rat
regulation of body fluid levelsGO:0050878900.023
agingGO:00075682410.023
t helper 1 type immune responseGO:004208810.022
regulation of response to stressGO:00801341260.022
Human Mouse Rat
positive regulation of multicellular organismal processGO:00512403870.022
Mouse
positive regulation of neuron projection developmentGO:0010976990.022
leukocyte mediated immunityGO:0002443280.022
Human Mouse Rat
neurological system processGO:00508772190.022
organelle organizationGO:00069962660.022
single organism reproductive processGO:00447022970.022
negative regulation of natural killer cell mediated immune response to tumor cellGO:000285610.022
Rat
hepatocyte proliferationGO:007257430.022
cellular nitrogen compound catabolic processGO:00442701630.022
angioblast cell migrationGO:003547610.022
divalent inorganic cation homeostasisGO:00725071650.022
cation homeostasisGO:00550801950.022
homeostatic processGO:00425923310.021
memoryGO:0007613540.021
regulation of neuron projection developmentGO:00109751610.021
organic acid metabolic processGO:00060822920.021
embryonic pattern specificationGO:000988010.021
positive regulation of secretionGO:00510471400.021
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.021
catabolic processGO:00090563510.021
regulation of neuron differentiationGO:00456642080.020
negative regulation of viral processGO:004852540.020
cell projection organizationGO:00300303020.020
single organism behaviorGO:00447081300.020
motor neuron axon guidanceGO:000804510.020
purine nucleoside triphosphate catabolic processGO:00091461220.020
alpha beta t cell activationGO:004663130.020
nucleoside phosphate catabolic processGO:19012921400.020
positive regulation of secretion by cellGO:19035321280.019
response to estradiolGO:00323551640.019
sexual reproductionGO:00199531480.019
negative regulation of multicellular organismal processGO:00512412030.019
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.019
cellular response to growth factor stimulusGO:00713631620.019
purine containing compound metabolic processGO:00725212530.019
divalent inorganic cation transportGO:00725111340.019
positive regulation of developmental processGO:00510942830.019
defense responseGO:00069521940.019
Human Mouse Rat
regulation of amine transportGO:0051952540.019
response to other organismGO:00517072200.019
Mouse
calcium mediated signalingGO:0019722230.019
peptide hormone secretionGO:0030072840.019
regulation of calcium ion transportGO:0051924770.018
regulation of transcription dna templatedGO:00063553740.018
cell chemotaxisGO:0060326310.018
inflammatory response to antigenic stimulusGO:0002437180.018
response to woundingGO:00096112540.018
ion homeostasisGO:00508012120.018
sequestering of metal ionGO:005123890.018
response to oxidative stressGO:00069791860.018
Rat
negative regulation of response to stimulusGO:00485851550.018
Rat
organophosphate metabolic processGO:00196373700.017
positive regulation of lymphocyte activationGO:0051251250.017
brain developmentGO:00074202470.017
purine nucleotide catabolic processGO:00061951360.017
positive regulation of necrotic cell deathGO:001094040.017
small gtpase mediated signal transductionGO:0007264360.017
calcium ion transport into cytosolGO:0060402380.017
response to biotic stimulusGO:00096072260.017
Mouse Rat
nucleobase containing small molecule metabolic processGO:00550863160.017
anatomical structure formation involved in morphogenesisGO:0048646830.017
negative regulation of long term synaptic potentiationGO:190027210.017
organophosphate catabolic processGO:00464341480.017
regulation of kinase activityGO:00435491170.017
positive regulation of protein kinase activityGO:0045860730.017
response to corticosteroidGO:00319602350.016
heart processGO:0003015570.016
lipid metabolic processGO:00066292830.016
sensory perceptionGO:00076001010.016
proteolysisGO:00065081750.016
negative regulation of response to biotic stimulusGO:000283240.016
Rat
cytokine mediated signaling pathwayGO:0019221430.016
ribonucleoside triphosphate catabolic processGO:00092031220.016
reproductionGO:00000032450.016
leukocyte cell cell adhesionGO:000715940.016
Rat
response to peptide hormoneGO:00434342780.016
negative regulation of biosynthetic processGO:00098901680.016
multicellular organismal reproductive processGO:00486092330.016
regulation of programmed cell deathGO:00430673410.016
positive regulation of catalytic activityGO:00430851840.016
negative regulation of cellular metabolic processGO:00313242810.016
heterocycle catabolic processGO:00467001670.016
cellular response to molecule of bacterial originGO:0071219560.016
Mouse
purine ribonucleoside catabolic processGO:00461301240.015
cell cell signalingGO:00072673350.015
response to estrogenGO:00436272320.015
regulation of peptide hormone secretionGO:0090276800.015
release of sequestered calcium ion into cytosolGO:0051209250.015
response to lipopolysaccharideGO:00324961910.015
Mouse
neuron projection developmentGO:00311752730.015
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.015
muscle cell differentiationGO:0042692520.015
purine nucleoside metabolic processGO:00422781690.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
leukocyte chemotaxisGO:0030595220.015
leukocyte differentiationGO:0002521300.015
circadian rhythmGO:0007623880.015
axis specificationGO:000979840.015
regulation of mononuclear cell proliferationGO:0032944260.015
mapk cascadeGO:00001651400.015
single organism organelle organizationGO:19025891800.015
central nervous system developmentGO:00074173110.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
regulation of heart contractionGO:0008016480.015
mast cell migrationGO:009753140.014
cellular ion homeostasisGO:00068731840.014
cardiac muscle contractionGO:0060048270.014
response to alkaloidGO:00432791320.014
regulation of behaviorGO:0050795610.014
positive regulation of cell deathGO:00109421840.014
positive regulation of phosphorus metabolic processGO:00105622620.014
regulation of cell killingGO:0031341120.014
Human Mouse Rat
anterior posterior pattern specificationGO:000995210.014
regulation of leukocyte differentiationGO:1902105200.014
cellular response to stressGO:00335542690.014
negative regulation of transcription dna templatedGO:00458921160.014
regulation of blood pressureGO:0008217830.014
regulation of protein kinase activityGO:00458591050.013
cation transportGO:00068123820.013
b cell activation involved in immune responseGO:000231210.013
insulin secretionGO:0030073690.013
organic cyclic compound catabolic processGO:19013611750.013
response to temperature stimulusGO:0009266940.013
positive regulation of cellular protein metabolic processGO:00322701670.013
response to insulinGO:00328681330.013
cell activationGO:0001775970.013
Mouse Rat
calcium ion transportGO:00068161310.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
maintenance of locationGO:0051235170.013
negative regulation of immune responseGO:0050777150.013
Rat
ribonucleoside metabolic processGO:00091191740.013
neuronal action potentialGO:0019228350.013
regulation of cell projection organizationGO:00313441750.013
nucleoside triphosphate catabolic processGO:00091431230.013
locomotionGO:00400112370.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
regulation of cellular protein metabolic processGO:00322682670.013
regulation of blood circulationGO:19035221100.013
biological adhesionGO:00226101100.013
Rat
glycosyl compound catabolic processGO:19016581260.013
learning or memoryGO:0007611900.013
response to calcium ionGO:0051592590.013
nucleoside triphosphate metabolic processGO:00091411440.013
carbohydrate derivative catabolic processGO:19011361470.013
organonitrogen compound catabolic processGO:19015651790.013
muscle contractionGO:0006936880.013
metal ion homeostasisGO:00550651860.012
tissue developmentGO:00098882520.012
sensory perception of painGO:0019233730.012
regulation of muscle contractionGO:0006937530.012
regulation of mapk cascadeGO:00434081160.012
mast cell chemotaxisGO:000255140.012
calcium ion transmembrane transportGO:0070588700.012
dna metabolic processGO:0006259960.012
glycosyl compound metabolic processGO:19016571820.012
inner ear morphogenesisGO:004247210.012
regulation of t cell activationGO:0050863230.012
retinal ganglion cell axon guidanceGO:003129010.012
cellular response to transforming growth factor beta stimulusGO:0071560410.012
regulation of hormone secretionGO:00468831060.012
regulation of system processGO:00440572080.012
cellular response to nitrogen compoundGO:19016992100.012
negative regulation of molecular functionGO:00440921330.012
response to growth factorGO:00708481890.012
negative regulation of protein metabolic processGO:00512481140.012
cellular response to organic cyclic compoundGO:00714072020.012
sequestering of calcium ionGO:005120880.012
response to ammonium ionGO:0060359710.012
establishment of protein localizationGO:00451841410.012
response to bacteriumGO:00096172000.012
Mouse
positive regulation of transferase activityGO:0051347810.012
regulation of cell proliferationGO:00421273590.012
cellular response to hormone stimulusGO:00328702470.011
positive regulation of cell differentiationGO:00455972170.011
nucleotide metabolic processGO:00091172790.011
erk1 and erk2 cascadeGO:0070371480.011
ribonucleotide metabolic processGO:00092592310.011
carbohydrate derivative biosynthetic processGO:19011371240.011
positive regulation of t cell activationGO:0050870170.011
nucleobase containing compound catabolic processGO:00346551520.011
carboxylic acid metabolic processGO:00197522890.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
cardiac chamber developmentGO:000320510.011
regulation of hydrolase activityGO:00513361430.011
oxoacid metabolic processGO:00434362900.011
positive regulation of protein metabolic processGO:00512471780.011
axonogenesisGO:0007409710.011
response to acid chemicalGO:00011012220.011
myeloid leukocyte migrationGO:0097529200.011
organelle localizationGO:0051640550.011
signal transduction by phosphorylationGO:00230141440.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
single organism cellular localizationGO:19025801020.011
regulation of protein metabolic processGO:00512462890.011
response to ionizing radiationGO:0010212590.011
response to hexoseGO:00097461440.011
reproductive processGO:00224143720.011
positive regulation of erk1 and erk2 cascadeGO:0070374290.011
positive regulation of ion transportGO:0043270940.011
response to cgmpGO:007030530.011
antigen receptor mediated signaling pathwayGO:005085110.011
protein processingGO:0016485680.011
interleukin 1 alpha productionGO:003261010.011
regulation of apoptotic processGO:00429813350.010
lipoprotein metabolic processGO:0042157150.010
Rat
nucleotide catabolic processGO:00091661390.010
cellular response to organonitrogen compoundGO:00714171970.010
spindle organizationGO:000705120.010
lipid storageGO:001991510.010
male gamete generationGO:0048232990.010
acid secretionGO:0046717480.010
ribose phosphate metabolic processGO:00196932350.010
regulation of vasculature developmentGO:1901342440.010
cognitionGO:0050890920.010
nucleoside catabolic processGO:00091641260.010
response to toxic substanceGO:00096361330.010
response to mineralocorticoidGO:0051385490.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.010
cellular response to biotic stimulusGO:0071216590.010
Mouse
t cell receptor signaling pathwayGO:005085210.010

Klrk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.063
cancerDOID:16200.063
organ system cancerDOID:005068600.037
musculoskeletal system diseaseDOID:1700.019
disease of anatomical entityDOID:700.019
gastrointestinal system cancerDOID:311900.018