| dicarboxylic acid catabolic process | GO:0043649 | 1 | 0.536 | |
| dicarboxylic acid metabolic process | GO:0043648 | 42 | 0.479 | |
| cofactor metabolic process | GO:0051186 | 95 | 0.386 | |
| coenzyme metabolic process | GO:0006732 | 86 | 0.377 | |
| nicotinamide nucleotide metabolic process | GO:0046496 | 28 | 0.335 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.208 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.202 | |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.197 | |
| acyl coa metabolic process | GO:0006637 | 28 | 0.189 | |
| generation of precursor metabolites and energy | GO:0006091 | 62 | 0.160 | |
| 2 oxoglutarate metabolic process | GO:0006103 | 6 | 0.143 | |
| oxidation reduction process | GO:0055114 | 304 | 0.135 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.132 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.116 | |
| pyridine containing compound metabolic process | GO:0072524 | 32 | 0.111 | |
| oxaloacetate metabolic process | GO:0006107 | 6 | 0.110 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.107 | |
| response to molecule of bacterial origin | GO:0002237 | 194 | 0.086 | |
| tricarboxylic acid metabolic process | GO:0072350 | 10 | 0.085 | |
| oxidoreduction coenzyme metabolic process | GO:0006733 | 31 | 0.085 | |
| response to oxidative stress | GO:0006979 | 186 | 0.083 | |
| nucleotide metabolic process | GO:0009117 | 279 | 0.081 | Yeast |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.079 | |
| cellular amino acid biosynthetic process | GO:0008652 | 32 | 0.076 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.070 | Yeast |
| programmed cell death | GO:0012501 | 392 | 0.068 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 46 | 0.064 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.063 | Yeast |
| cellular respiration | GO:0045333 | 21 | 0.062 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.061 | Yeast |
| regulation of phosphorylation | GO:0042325 | 248 | 0.057 | |
| glutamine family amino acid biosynthetic process | GO:0009084 | 2 | 0.057 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.056 | |
| positive regulation of programmed cell death | GO:0043068 | 157 | 0.054 | |
| carbohydrate catabolic process | GO:0016052 | 40 | 0.051 | |
| glutamate metabolic process | GO:0006536 | 3 | 0.050 | |
| response to temperature stimulus | GO:0009266 | 94 | 0.050 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.049 | Yeast |
| cellular response to stress | GO:0033554 | 269 | 0.047 | |
| pyridine nucleotide metabolic process | GO:0019362 | 28 | 0.044 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.044 | |
| nadh metabolic process | GO:0006734 | 10 | 0.041 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.041 | |
| cellular homeostasis | GO:0019725 | 252 | 0.040 | |
| reproductive process | GO:0022414 | 372 | 0.038 | |
| cation transport | GO:0006812 | 382 | 0.038 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.038 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.036 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.035 | |
| response to peptide hormone | GO:0043434 | 278 | 0.034 | |
| cation homeostasis | GO:0055080 | 195 | 0.034 | |
| carbohydrate metabolic process | GO:0005975 | 130 | 0.034 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.033 | |
| protein processing | GO:0016485 | 68 | 0.033 | |
| protein maturation | GO:0051604 | 68 | 0.033 | |
| synaptic transmission | GO:0007268 | 235 | 0.033 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 38 | 0.032 | |
| protein phosphorylation | GO:0006468 | 345 | 0.032 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.031 | |
| nad metabolic process | GO:0019674 | 15 | 0.031 | |
| regulation of cell development | GO:0060284 | 263 | 0.031 | |
| head development | GO:0060322 | 247 | 0.031 | |
| regulation of nervous system development | GO:0051960 | 264 | 0.030 | |
| positive regulation of signal transduction | GO:0009967 | 175 | 0.029 | |
| feeding behavior | GO:0007631 | 53 | 0.029 | |
| response to nutrient levels | GO:0031667 | 370 | 0.028 | |
| female pregnancy | GO:0007565 | 122 | 0.028 | |
| gonad development | GO:0008406 | 104 | 0.028 | |
| response to corticosteroid | GO:0031960 | 235 | 0.028 | |
| cellular response to reactive oxygen species | GO:0034614 | 55 | 0.027 | |
| response to reactive oxygen species | GO:0000302 | 120 | 0.027 | |
| apoptotic process | GO:0006915 | 381 | 0.027 | |
| single organism catabolic process | GO:0044712 | 283 | 0.027 | Yeast |
| positive regulation of cell death | GO:0010942 | 184 | 0.027 | |
| alpha amino acid biosynthetic process | GO:1901607 | 23 | 0.026 | |
| response to toxic substance | GO:0009636 | 133 | 0.026 | |
| homeostatic process | GO:0042592 | 331 | 0.026 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.025 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.025 | |
| positive regulation of multicellular organismal process | GO:0051240 | 387 | 0.025 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.024 | |
| monocarboxylic acid metabolic process | GO:0032787 | 152 | 0.024 | |
| proteolysis | GO:0006508 | 175 | 0.024 | |
| ion homeostasis | GO:0050801 | 212 | 0.024 | |
| regulation of kinase activity | GO:0043549 | 117 | 0.023 | |
| mapk cascade | GO:0000165 | 140 | 0.023 | |
| glutamate catabolic process | GO:0006538 | 1 | 0.023 | |
| response to lipopolysaccharide | GO:0032496 | 191 | 0.023 | |
| single organism reproductive process | GO:0044702 | 297 | 0.023 | |
| regulation of response to stress | GO:0080134 | 126 | 0.022 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.022 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.022 | |
| reproductive structure development | GO:0048608 | 128 | 0.021 | |
| brain development | GO:0007420 | 247 | 0.021 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.021 | |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.021 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.021 | |
| alpha amino acid metabolic process | GO:1901605 | 71 | 0.021 | |
| central nervous system development | GO:0007417 | 311 | 0.021 | |
| regulation of molecular function | GO:0065009 | 398 | 0.020 | |
| monovalent inorganic cation transport | GO:0015672 | 172 | 0.020 | |
| cellular metal ion homeostasis | GO:0006875 | 172 | 0.020 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.020 | |
| negative regulation of signal transduction | GO:0009968 | 83 | 0.020 | |
| response to nutrient | GO:0007584 | 248 | 0.020 | |
| mitochondrion organization | GO:0007005 | 35 | 0.020 | Yeast |
| glutamine family amino acid metabolic process | GO:0009064 | 15 | 0.019 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.019 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.019 | |
| positive regulation of apoptotic process | GO:0043065 | 154 | 0.019 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.018 | |
| response to transition metal nanoparticle | GO:1990267 | 122 | 0.018 | |
| transcription dna templated | GO:0006351 | 377 | 0.018 | |
| negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902176 | 2 | 0.018 | |
| development of primary sexual characteristics | GO:0045137 | 107 | 0.018 | |
| catabolic process | GO:0009056 | 351 | 0.018 | Yeast |
| circulatory system process | GO:0003013 | 183 | 0.018 | |
| cell migration | GO:0016477 | 197 | 0.018 | |
| regulation of hydrolase activity | GO:0051336 | 143 | 0.018 | |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.018 | |
| protein complex biogenesis | GO:0070271 | 263 | 0.018 | |
| response to activity | GO:0014823 | 73 | 0.017 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 124 | 0.017 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.017 | Yeast |
| cellular cation homeostasis | GO:0030003 | 180 | 0.017 | |
| positive regulation of neurogenesis | GO:0050769 | 165 | 0.017 | |
| gamete generation | GO:0007276 | 124 | 0.017 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.017 | |
| response to peptide | GO:1901652 | 292 | 0.017 | |
| response to bacterium | GO:0009617 | 200 | 0.016 | |
| small molecule biosynthetic process | GO:0044283 | 124 | 0.016 | |
| tricarboxylic acid cycle | GO:0006099 | 11 | 0.016 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.016 | Yeast |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.016 | |
| positive regulation of catalytic activity | GO:0043085 | 184 | 0.016 | |
| regulation of ion transport | GO:0043269 | 245 | 0.016 | |
| growth | GO:0040007 | 165 | 0.016 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.016 | |
| positive regulation of immune system process | GO:0002684 | 90 | 0.015 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.015 | |
| chemical homeostasis | GO:0048878 | 292 | 0.015 | |
| regeneration | GO:0031099 | 163 | 0.015 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.015 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.015 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.015 | |
| response to acid chemical | GO:0001101 | 222 | 0.015 | |
| ion transmembrane transport | GO:0034220 | 365 | 0.015 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.015 | Yeast |
| thioester metabolic process | GO:0035383 | 28 | 0.015 | |
| metal ion homeostasis | GO:0055065 | 186 | 0.015 | |
| alpha amino acid catabolic process | GO:1901606 | 20 | 0.015 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 167 | 0.014 | |
| immune system process | GO:0002376 | 204 | 0.014 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 4 | 0.014 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.014 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.014 | |
| cellular component assembly | GO:0022607 | 360 | 0.014 | |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.014 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.014 | |
| amine metabolic process | GO:0009308 | 38 | 0.014 | |
| purine nucleoside metabolic process | GO:0042278 | 169 | 0.014 | Yeast |
| multi multicellular organism process | GO:0044706 | 138 | 0.014 | |
| brain renin angiotensin system | GO:0002035 | 3 | 0.014 | |
| cellular response to hormone stimulus | GO:0032870 | 247 | 0.014 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.014 | Yeast |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.014 | |
| nucleoside metabolic process | GO:0009116 | 179 | 0.014 | Yeast |
| organic acid biosynthetic process | GO:0016053 | 83 | 0.014 | |
| response to estrogen | GO:0043627 | 232 | 0.013 | |
| sex differentiation | GO:0007548 | 113 | 0.013 | |
| cell projection organization | GO:0030030 | 302 | 0.013 | |
| cellular amino acid catabolic process | GO:0009063 | 21 | 0.013 | |
| response to inorganic substance | GO:0010035 | 377 | 0.013 | |
| organic acid catabolic process | GO:0016054 | 49 | 0.013 | |
| rna metabolic process | GO:0016070 | 406 | 0.013 | |
| ribonucleotide metabolic process | GO:0009259 | 231 | 0.013 | Yeast |
| positive regulation of signaling | GO:0023056 | 270 | 0.013 | |
| regulation of neuron differentiation | GO:0045664 | 208 | 0.013 | |
| cellular ion homeostasis | GO:0006873 | 184 | 0.013 | |
| single organism carbohydrate metabolic process | GO:0044723 | 118 | 0.013 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.013 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.012 | |
| positive regulation of cell development | GO:0010720 | 176 | 0.012 | |
| regulation of growth | GO:0040008 | 105 | 0.012 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.012 | |
| positive regulation of hydrolase activity | GO:0051345 | 86 | 0.012 | |
| positive regulation of developmental process | GO:0051094 | 283 | 0.012 | |
| response to oxygen levels | GO:0070482 | 265 | 0.012 | |
| protein complex assembly | GO:0006461 | 263 | 0.012 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.011 | |
| metal ion transport | GO:0030001 | 289 | 0.011 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.011 | |
| ras protein signal transduction | GO:0007265 | 29 | 0.011 | |
| positive regulation of intracellular signal transduction | GO:1902533 | 138 | 0.011 | |
| liver development | GO:0001889 | 90 | 0.011 | |
| apoptotic signaling pathway | GO:0097190 | 27 | 0.011 | |
| regulation of peptidase activity | GO:0052547 | 55 | 0.011 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 31 | 0.011 | |
| cellular response to lipid | GO:0071396 | 201 | 0.011 | |
| cell cell signaling | GO:0007267 | 335 | 0.011 | |
| response to organophosphorus | GO:0046683 | 102 | 0.011 | |
| regulation of system process | GO:0044057 | 208 | 0.011 | |
| response to mechanical stimulus | GO:0009612 | 134 | 0.010 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.010 | |
| cellular response to organic cyclic compound | GO:0071407 | 202 | 0.010 | |
| cellular response to alcohol | GO:0097306 | 87 | 0.010 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.010 | |
| endocytosis | GO:0006897 | 84 | 0.010 | |
