Rattus norvegicus

50 known processes

Scn2a1

sodium channel, voltage-gated, type II, alpha 1

(Aliases: Nav1.2,SCN,NachII,SCN2A,Scn2a2,RNSCPIIR,ScpII,RII/RIIA)

Scn2a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell cell signalingGO:00072673350.275
anatomical structure morphogenesisGO:00096532980.241
transmembrane transportGO:00550854120.222
secretionGO:00469033070.210
cell projection organizationGO:00300303020.209
regulation of cell developmentGO:00602842630.200
neuron developmentGO:00486662860.197
cellular response to endogenous stimulusGO:00714953770.193
metal ion transportGO:00300012890.181
neuron differentiationGO:00301823680.172
regulation of cellular component organizationGO:00511283680.150
regulation of multicellular organismal developmentGO:20000263760.148
cell projection morphogenesisGO:00488581230.144
positive regulation of cell communicationGO:00106472710.135
carboxylic acid metabolic processGO:00197522890.129
cell morphogenesisGO:00009021420.123
regulation of secretionGO:00510462240.116
intracellular transportGO:00469071850.113
organophosphate metabolic processGO:00196373700.111
positive regulation of transportGO:00510502450.110
nucleoside phosphate metabolic processGO:00067532830.109
organic acid metabolic processGO:00060822920.103
anion transportGO:00068201780.101
neuron projection developmentGO:00311752730.098
regulation of signal transductionGO:00099663180.096
regulation of ion transportGO:00432692450.093
purine ribonucleoside metabolic processGO:00461281680.091
cellular component morphogenesisGO:00329891550.090
protein complex subunit organizationGO:00718223020.089
neuron projection morphogenesisGO:00488121220.081
regulation of rna metabolic processGO:00512523910.081
positive regulation of signalingGO:00230562700.079
cellular macromolecule localizationGO:00707271220.078
organic substance catabolic processGO:19015753160.074
cell morphogenesis involved in neuron differentiationGO:00486671060.073
regulation of phosphate metabolic processGO:00192203490.071
regulation of phosphorus metabolic processGO:00511743490.071
organic anion transportGO:00157111320.070
transcription from rna polymerase ii promoterGO:00063662520.067
cation transmembrane transportGO:00986552630.067
cell part morphogenesisGO:00329901230.063
oxoacid metabolic processGO:00434362900.062
catabolic processGO:00090563510.061
ribonucleotide catabolic processGO:00092611360.060
nitrogen compound transportGO:00717052290.060
Rat
intracellular signal transductionGO:00355563140.059
Mouse
ribonucleoside metabolic processGO:00091191740.059
response to nutrient levelsGO:00316673700.059
regulation of nucleic acid templated transcriptionGO:19035063800.058
regulation of intracellular signal transductionGO:19025312180.058
nucleoside metabolic processGO:00091161790.057
regulation of cellular catabolic processGO:00313291010.056
intracellular protein transportGO:0006886790.056
ribonucleoside triphosphate metabolic processGO:00091991410.056
regulation of secretion by cellGO:19035302080.056
cellular component assemblyGO:00226073600.055
purine ribonucleotide catabolic processGO:00091541360.055
regulation of protein metabolic processGO:00512462890.053
apoptotic processGO:00069153810.052
Mouse
aromatic compound catabolic processGO:00194391680.052
response to extracellular stimulusGO:00099913800.052
purine ribonucleoside triphosphate metabolic processGO:00092051400.052
regulation of hydrolase activityGO:00513361430.051
purine nucleoside catabolic processGO:00061521240.051
positive regulation of multicellular organismal processGO:00512403870.051
regulation of molecular functionGO:00650093980.050
cellular nitrogen compound catabolic processGO:00442701630.050
ribonucleoside triphosphate catabolic processGO:00092031220.050
regulation of cellular amino acid metabolic processGO:000652120.049
regulation of nervous system developmentGO:00519602640.049
purine ribonucleotide metabolic processGO:00091502270.049
cellular response to hormone stimulusGO:00328702470.049
regulation of catabolic processGO:00098941130.049
purine ribonucleoside catabolic processGO:00461301240.048
regulation of cellular localizationGO:00603412630.048
cellular ketone metabolic processGO:0042180510.048
macromolecule localizationGO:00330362520.047
cellular protein localizationGO:00346131220.047
single organism catabolic processGO:00447122830.046
peptide secretionGO:0002790860.046
regulation of cellular amine metabolic processGO:003323880.046
nucleotide metabolic processGO:00091172790.046
regulation of cell differentiationGO:00455953200.046
cellular response to organonitrogen compoundGO:00714171970.045
protein complex assemblyGO:00064612630.045
positive regulation of nucleobase containing compound metabolic processGO:00459353190.045
purine nucleoside triphosphate catabolic processGO:00091461220.044
glycosyl compound catabolic processGO:19016581260.044
cellular response to oxygen containing compoundGO:19017013860.044
organic cyclic compound catabolic processGO:19013611750.044
purine nucleotide metabolic processGO:00061632290.043
lipid metabolic processGO:00066292830.043
cellular amine metabolic processGO:0044106380.043
positive regulation of nitrogen compound metabolic processGO:00511733340.043
regulation of transcription dna templatedGO:00063553740.043
multicellular organism reproductionGO:00325042330.042
purine nucleoside triphosphate metabolic processGO:00091441410.042
purine nucleoside metabolic processGO:00422781690.042
purine containing compound catabolic processGO:00725231380.041
nucleoside phosphate catabolic processGO:19012921400.041
macromolecular complex assemblyGO:00650032730.041
monovalent inorganic cation transportGO:00156721720.040
single organism biosynthetic processGO:00447113420.040
regulation of phosphatidylinositol dephosphorylationGO:006030410.040
single organism intracellular transportGO:19025821660.039
protein homooligomerizationGO:0051260910.039
regulation of hormone levelsGO:00108171870.039
cellular response to nitrogen compoundGO:19016992100.039
glycosyl compound metabolic processGO:19016571820.038
carbohydrate derivative metabolic processGO:19011353460.038
cation transportGO:00068123820.038
purine ribonucleoside triphosphate catabolic processGO:00092071220.038
protein phosphorylationGO:00064683450.037
regulation of neurogenesisGO:00507672470.037
positive regulation of cell developmentGO:00107201760.037
nucleobase containing small molecule metabolic processGO:00550863160.037
response to external biotic stimulusGO:00432072210.037
amino acid transportGO:0006865700.037
regulation of phosphorylationGO:00423252480.036
nucleotide catabolic processGO:00091661390.036
positive regulation of cell deathGO:00109421840.036
organophosphate catabolic processGO:00464341480.035
lipid modificationGO:0030258520.035
regulation of blood circulationGO:19035221100.035
peptide hormone secretionGO:0030072840.035
inorganic ion transmembrane transportGO:00986602290.034
neurological system processGO:00508772190.034
multi organism reproductive processGO:00447032620.034
brain developmentGO:00074202470.033
regulation of peptide transportGO:0090087870.033
purine nucleotide catabolic processGO:00061951360.033
regulation of neuron deathGO:19012141150.033
response to toxic substanceGO:00096361330.033
cellular catabolic processGO:00442482950.032
positive regulation of phosphate metabolic processGO:00459372620.032
amine metabolic processGO:0009308380.032
monocarboxylic acid metabolic processGO:00327871520.032
purine containing compound metabolic processGO:00725212530.032
axon developmentGO:0061564960.031
protein oligomerizationGO:00512591910.031
regulation of neuron differentiationGO:00456642080.031
transcription dna templatedGO:00063513770.031
vesicle mediated transportGO:00161921810.031
positive regulation of cellular biosynthetic processGO:00313282950.030
organonitrogen compound catabolic processGO:19015651790.030
positive regulation of response to stimulusGO:00485842850.030
tube developmentGO:0035295890.030
heart morphogenesisGO:000300730.029
regulation of catalytic activityGO:00507903040.029
heterocycle catabolic processGO:00467001670.029
programmed cell deathGO:00125013920.029
Mouse
phosphatidylinositol dephosphorylationGO:004685640.029
cell morphogenesis involved in differentiationGO:00009041190.029
single organism cellular localizationGO:19025801020.029
regulation of anatomical structure sizeGO:00900661350.029
regulation of apoptotic processGO:00429813350.029
macromolecular complex subunit organizationGO:00439333390.028
nucleoside triphosphate catabolic processGO:00091431230.028
positive regulation of developmental processGO:00510942830.028
regulation of cellular ketone metabolic processGO:0010565270.028
carbohydrate derivative catabolic processGO:19011361470.028
insulin secretionGO:0030073690.028
cellular response to peptideGO:19016531330.027
establishment of vesicle localizationGO:0051650310.027
cellular amino acid metabolic processGO:00065201070.027
protein localizationGO:00081041910.027
synaptic transmissionGO:00072682350.027
establishment of protein localizationGO:00451841410.027
response to peptideGO:19016522920.027
protein complex biogenesisGO:00702712630.027
negative regulation of apoptotic processGO:00430661810.026
peptide transportGO:0015833970.026
exocytosisGO:0006887600.026
cell type specific apoptotic processGO:00972851340.026
Mouse
regulation of metal ion transportGO:00109591180.026
ion transmembrane transportGO:00342203650.026
nucleic acid templated transcriptionGO:00976593790.026
eye morphogenesisGO:004859240.026
regenerationGO:00310991630.025
regulation of peptide secretionGO:0002791820.025
head developmentGO:00603222470.025
positive regulation of purine nucleotide metabolic processGO:1900544910.025
axis specificationGO:000979840.025
reproductive processGO:00224143720.025
cellular response to external stimulusGO:00714961180.025
guanosine containing compound metabolic processGO:1901068740.025
blood circulationGO:00080151830.025
cellular lipid metabolic processGO:00442552080.025
positive regulation of neurotransmitter secretionGO:000195690.025
positive regulation of signal transductionGO:00099671750.024
organic hydroxy compound metabolic processGO:19016151150.024
nucleoside monophosphate metabolic processGO:0009123930.024
ribonucleoside catabolic processGO:00424541260.024
regulation of neuron apoptotic processGO:0043523830.024
protein transportGO:00150311320.024
single organism behaviorGO:00447081300.024
positive regulation of neuron projection developmentGO:0010976990.024
regulation of peptide hormone secretionGO:0090276800.023
regulation of neuron projection developmentGO:00109751610.023
response to corticosteroidGO:00319602350.023
homeostatic processGO:00425923310.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
central nervous system developmentGO:00074173110.023
nucleoside catabolic processGO:00091641260.023
rna biosynthetic processGO:00327743800.023
regulation of vesicle mediated transportGO:0060627810.023
nucleoside triphosphate metabolic processGO:00091411440.023
positive regulation of gene expressionGO:00106282440.023
positive regulation of cellular component organizationGO:00511302000.023
cellular component biogenesisGO:00440853680.022
response to monosaccharideGO:00342841590.022
ras protein signal transductionGO:0007265290.022
negative regulation of biosynthetic processGO:00098901680.022
response to mechanical stimulusGO:00096121340.022
regulation of rna biosynthetic processGO:20011413810.022
growthGO:00400071650.022
amide transportGO:00428861050.022
response to growth factorGO:00708481890.022
response to oxidative stressGO:00069791860.021
response to insulinGO:00328681330.021
anterior posterior pattern specificationGO:000995210.021
nucleobase containing compound catabolic processGO:00346551520.021
negative regulation of cell deathGO:00605482290.021
positive regulation of nervous system developmentGO:00519621780.021
rna metabolic processGO:00160704060.021
response to metal ionGO:00100382530.021
response to ethanolGO:00454711620.021
regulation of system processGO:00440572080.021
embryonic pattern specificationGO:000988010.021
positive regulation of ion transportGO:0043270940.021
positive regulation of secretionGO:00510471400.021
negative regulation of macromolecule metabolic processGO:00106052600.021
ribonucleotide metabolic processGO:00092592310.021
regulation of insulin secretionGO:0050796650.021
response to bacteriumGO:00096172000.021
ribose phosphate metabolic processGO:00196932350.020
response to biotic stimulusGO:00096072260.020
heart developmentGO:0007507720.020
regulation of cell proliferationGO:00421273590.020
neuromuscular synaptic transmissionGO:000727420.020
reproductionGO:00000032450.020
regulation of hormone secretionGO:00468831060.020
positive regulation of rna metabolic processGO:00512542030.020
lipid biosynthetic processGO:00086101280.020
regulation of proteasomal protein catabolic processGO:006113640.020
centrosome organizationGO:005129710.020
response to nutrientGO:00075842480.020
membrane organizationGO:0061024940.020
cellular response to stressGO:00335542690.020
Mouse
cell cycleGO:00070491010.020
atp metabolic processGO:0046034720.020
response to peptide hormoneGO:00434342780.020
sensory perceptionGO:00076001010.019
carboxylic acid transportGO:00469421150.019
cellular component movementGO:00069282480.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
response to glucocorticoidGO:00513842230.019
positive regulation of catalytic activityGO:00430851840.019
negative regulation of gene expressionGO:00106291990.019
axonogenesisGO:0007409710.019
sensory organ developmentGO:0007423740.019
purine nucleoside monophosphate metabolic processGO:0009126840.019
cellular response to alcoholGO:0097306870.019
regulation of reactive oxygen species metabolic processGO:2000377260.018
positive regulation of phosphorylationGO:00423271770.018
cell cycle processGO:0022402570.018
developmental process involved in reproductionGO:00030061590.018
learning or memoryGO:0007611900.018
positive regulation of cellular amine metabolic processGO:003324030.018
peptidyl amino acid modificationGO:00181931260.018
hormone secretionGO:00468791150.018
positive regulation of biosynthetic processGO:00098913190.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
regulation of purine nucleotide catabolic processGO:0033121650.018
response to hypoxiaGO:00016662310.018
negative regulation of programmed cell deathGO:00430691830.018
dna metabolic processGO:0006259960.018
single organism reproductive processGO:00447022970.017
regulation of purine nucleotide metabolic processGO:19005421150.017
response to ketoneGO:19016541820.017
g protein coupled receptor signaling pathwayGO:00071862420.017
embryonic axis specificationGO:000057810.017
hormone transportGO:00099141210.017
secretion by cellGO:00329402480.017
negative regulation of metabolic processGO:00098923310.017
eye developmentGO:0001654500.017
positive regulation of phosphorus metabolic processGO:00105622620.017
organic acid transportGO:00158491160.017
regulation of nucleoside metabolic processGO:0009118660.017
multicellular organismal reproductive processGO:00486092330.017
gtp metabolic processGO:0046039720.017
positive regulation of cell proliferationGO:00082842490.017
response to cytokineGO:00340972150.017
regulation of protein transportGO:0051223680.017
glutamate receptor signaling pathwayGO:0007215430.017
regulation of embryonic developmentGO:004599520.017
response to histamineGO:003477630.017
positive regulation of protein metabolic processGO:00512471780.017
positive regulation of cellular catabolic processGO:0031331710.017
negative regulation of cellular metabolic processGO:00313242810.016
cognitionGO:0050890920.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
neuron apoptotic processGO:0051402880.016
Mouse
regulation of protein modification processGO:00313991940.016
negative regulation of cellular biosynthetic processGO:00313271610.016
regulation of cell cycleGO:0051726730.016
regulation of membrane potentialGO:00423911100.016
endomembrane system organizationGO:0010256480.016
cardiac conductionGO:006133720.016
response to calcium ionGO:0051592590.016
regulation of programmed cell deathGO:00430673410.016
positive regulation of catabolic processGO:0009896780.015
cell adhesionGO:00071551100.015
organelle organizationGO:00069962660.015
negative regulation of secretionGO:0051048820.015
axon guidanceGO:0007411240.015
regulation of anatomical structure morphogenesisGO:00226031410.015
positive regulation of molecular functionGO:00440932300.015
regulation of lipid metabolic processGO:0019216680.015
ribonucleoside monophosphate metabolic processGO:0009161880.015
regulation of cell projection organizationGO:00313441750.015
cellular response to insulin stimulusGO:0032869810.015
dendrite developmentGO:0016358720.015
regulation of synaptic transmissionGO:00508041410.015
positive regulation of secretion by cellGO:19035321280.014
single organism organelle organizationGO:19025891800.014
response to organophosphorusGO:00466831020.014
response to estrogenGO:00436272320.014
regulation of blood vessel sizeGO:0050880890.014
embryo developmentGO:0009790490.014
regulation of cell maturationGO:190342930.014
protein autophosphorylationGO:0046777660.014
peptidyl tyrosine modificationGO:0018212720.014
divalent inorganic cation transportGO:00725111340.014
cell growthGO:00160491040.014
positive regulation of mesenchymal cell proliferationGO:000205340.014
response to glucoseGO:00097491360.014
regulation of transmembrane transportGO:00347621220.014
gtp catabolic processGO:0006184710.014
response to axon injuryGO:0048678590.014
synaptic vesicle endocytosisGO:004848840.014
potassium ion transportGO:0006813970.014
Rat
regulation of smooth muscle cell proliferationGO:0048660750.013
synaptic transmission glycinergicGO:006001220.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
regulation of protein phosphorylationGO:00019321830.013
cellular response to growth factor stimulusGO:00713631620.013
negative regulation of multicellular organismal processGO:00512412030.013
calcium ion transportGO:00068161310.013
gamete generationGO:00072761240.013
multi multicellular organism processGO:00447061380.013
negative regulation of neuron deathGO:1901215690.013
alcohol metabolic processGO:0006066770.013
cellular chemical homeostasisGO:00550822470.013
cellular response to organic cyclic compoundGO:00714072020.013
positive regulation of cell differentiationGO:00455972170.013
regulation of organic acid transportGO:0032890350.013
positive regulation of apoptotic processGO:00430651540.013
behaviorGO:00076102050.013
positive regulation of programmed cell deathGO:00430681570.013
inflammatory responseGO:00069541500.013
small molecule biosynthetic processGO:00442831240.013
locomotionGO:00400112370.013
negative regulation of cellular component organizationGO:0051129830.012
ion homeostasisGO:00508012120.012
regulation of cellular component biogenesisGO:0044087860.012
regulation of cell growthGO:0001558850.012
response to hexoseGO:00097461440.012
regulation of cell cycle g2 m phase transitionGO:190274940.012
regulation of mapk cascadeGO:00434081160.012
negative regulation of transportGO:00510511360.012
cellular homeostasisGO:00197252520.012
cellular response to abiotic stimulusGO:0071214850.012
Mouse
negative regulation of cell proliferationGO:00082851190.012
cellular response to peptide hormone stimulusGO:00713751200.012
metaphase anaphase transition of cell cycleGO:004478410.012
regulation of neurotransmitter levelsGO:0001505420.012
response to other organismGO:00517072200.012
inorganic cation transmembrane transportGO:00986622020.012
regulation of tube sizeGO:0035150890.012
response to carbohydrateGO:00097431830.012
positive regulation of cellular protein metabolic processGO:00322701670.012
response to purine containing compoundGO:00140741260.012
positive regulation of transcription dna templatedGO:00458931970.012
purine ribonucleoside monophosphate catabolic processGO:0009169550.012
negative regulation of ion transportGO:0043271510.012
rna localizationGO:000640340.011
cytoplasmic transportGO:00164821150.011
signal transduction by phosphorylationGO:00230141440.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
cardiovascular system developmentGO:00723581340.011
proteolysisGO:00065081750.011
organ morphogenesisGO:0009887750.011
regulation of growthGO:00400081050.011
regulation of cellular protein metabolic processGO:00322682670.011
neurotransmitter gated ion channel clusteringGO:007257830.011
sexual reproductionGO:00199531480.011
positive regulation of cell projection organizationGO:00313461110.011
positive regulation of growthGO:0045927550.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
taxisGO:0042330670.011
regulation of organelle organizationGO:0033043800.011
regulation of ion transmembrane transporter activityGO:0032412480.011
glycerolipid metabolic processGO:0046486670.011
regulation of ion transmembrane transportGO:00347651210.011
chemical homeostasisGO:00488782920.011
regulation of protein localizationGO:0032880810.011
regulation of nucleotide catabolic processGO:0030811650.011
protein targetingGO:0006605610.011
anion transmembrane transportGO:0098656770.011
circulatory system processGO:00030131830.011
neurotransmitter transportGO:0006836420.011
positive regulation of purine nucleotide catabolic processGO:0033123530.011
regulation of homeostatic processGO:00328441010.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
regulation of sodium ion transmembrane transporter activityGO:200064940.011
positive regulation of gtp catabolic processGO:0033126480.011
guanosine containing compound catabolic processGO:1901069710.011
negative regulation of secretion by cellGO:1903531720.011
small gtpase mediated signal transductionGO:0007264360.011
negative regulation of protein metabolic processGO:00512481140.011
biological adhesionGO:00226101100.011
positive regulation of intracellular protein transportGO:0090316200.010
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.010
rho protein signal transductionGO:0007266110.010
positive regulation of cardiac muscle contractionGO:006045240.010
endocytosisGO:0006897840.010
signal releaseGO:00230611450.010
positive regulation of hydrolase activityGO:0051345860.010
tissue developmentGO:00098882520.010
positive regulation of intracellular signal transductionGO:19025331380.010
cellular cation homeostasisGO:00300031800.010
regulation of action potentialGO:0098900140.010
negative regulation of signalingGO:00230571570.010
microtubule organizing center organizationGO:003102310.010
negative regulation of macromolecule biosynthetic processGO:00105581480.010
cellular response to lipidGO:00713962010.010
regulation of nucleotide metabolic processGO:00061401170.010
multicellular organismal signalingGO:0035637440.010
single organism membrane organizationGO:0044802740.010
olfactory behaviorGO:004204820.010
adult locomotory behaviorGO:000834440.010
peptidyl serine phosphorylationGO:0018105330.010
regulation of anion transportGO:0044070430.010

Scn2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
Human
nervous system diseaseDOID:86300.043
Human
central nervous system diseaseDOID:33100.031
Human
brain diseaseDOID:93600.011
Human
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011