Rattus norvegicus

184 known processes

Pam

peptidylglycine alpha-amidating monooxygenase

Pam biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell cell signalingGO:00072673350.380
Rat
intracellular signal transductionGO:00355563140.187
protein complex subunit organizationGO:00718223020.175
regulation of cell proliferationGO:00421273590.171
positive regulation of multicellular organismal processGO:00512403870.168
cation homeostasisGO:00550801950.155
positive regulation of signalingGO:00230562700.150
central nervous system developmentGO:00074173110.139
inorganic cation transmembrane transportGO:00986622020.136
regulation of molecular functionGO:00650093980.134
apoptotic processGO:00069153810.130
cellular divalent inorganic cation homeostasisGO:00725031620.130
cellular catabolic processGO:00442482950.129
organic substance catabolic processGO:19015753160.127
neuron developmentGO:00486662860.124
positive regulation of response to stimulusGO:00485842850.123
homeostatic processGO:00425923310.122
Rat
head developmentGO:00603222470.119
positive regulation of cell communicationGO:00106472710.116
nucleobase containing small molecule metabolic processGO:00550863160.116
cellular response to organic cyclic compoundGO:00714072020.114
Rat
single organism catabolic processGO:00447122830.113
regulation of apoptotic processGO:00429813350.113
ribonucleotide catabolic processGO:00092611360.111
cellular calcium ion homeostasisGO:00068741600.111
purine containing compound catabolic processGO:00725231380.110
cation transmembrane transportGO:00986552630.109
catabolic processGO:00090563510.109
regulation of multicellular organismal developmentGO:20000263760.106
organophosphate metabolic processGO:00196373700.106
cellular component movementGO:00069282480.103
purine ribonucleotide catabolic processGO:00091541360.103
nucleoside phosphate metabolic processGO:00067532830.102
cellular homeostasisGO:00197252520.101
regulation of phosphate metabolic processGO:00192203490.098
neuron differentiationGO:00301823680.096
organophosphate catabolic processGO:00464341480.095
cellular ion homeostasisGO:00068731840.094
organonitrogen compound catabolic processGO:19015651790.094
cellular metal ion homeostasisGO:00068751720.093
cation transportGO:00068123820.093
regulation of signal transductionGO:00099663180.093
response to bacteriumGO:00096172000.092
response to woundingGO:00096112540.091
calcium ion homeostasisGO:00550741620.088
regulation of nervous system developmentGO:00519602640.088
nucleotide metabolic processGO:00091172790.088
purine nucleotide catabolic processGO:00061951360.086
response to oxygen levelsGO:00704822650.084
ion homeostasisGO:00508012120.084
response to hypoxiaGO:00016662310.083
ribonucleotide metabolic processGO:00092592310.083
heterocycle catabolic processGO:00467001670.082
cellular chemical homeostasisGO:00550822470.081
secretion by cellGO:00329402480.081
cell projection organizationGO:00300303020.081
regulation of neurogenesisGO:00507672470.081
inorganic ion transmembrane transportGO:00986602290.078
hormone secretionGO:00468791150.078
response to extracellular stimulusGO:00099913800.077
cellular component assemblyGO:00226073600.077
positive regulation of intracellular signal transductionGO:19025331380.076
regulation of hormone levelsGO:00108171870.075
regulation of intracellular signal transductionGO:19025312180.074
regulation of secretionGO:00510462240.074
synaptic transmissionGO:00072682350.074
Rat
ribose phosphate metabolic processGO:00196932350.073
divalent inorganic cation homeostasisGO:00725071650.073
purine nucleoside catabolic processGO:00061521240.072
carbohydrate derivative catabolic processGO:19011361470.070
signal releaseGO:00230611450.070
brain developmentGO:00074202470.069
aromatic compound catabolic processGO:00194391680.069
positive regulation of transportGO:00510502450.069
response to other organismGO:00517072200.069
purine nucleotide metabolic processGO:00061632290.068
protein complex assemblyGO:00064612630.068
nucleoside triphosphate metabolic processGO:00091411440.068
purine ribonucleotide metabolic processGO:00091502270.067
purine ribonucleoside triphosphate metabolic processGO:00092051400.067
protein complex biogenesisGO:00702712630.067
anatomical structure morphogenesisGO:00096532980.066
regulation of cellular component organizationGO:00511283680.066
cellular cation homeostasisGO:00300031800.066
response to glucocorticoidGO:00513842230.066
circulatory system processGO:00030131830.065
metal ion transportGO:00300012890.065
neuron projection developmentGO:00311752730.065
regulation of cell differentiationGO:00455953200.065
regulation of nucleotide metabolic processGO:00061401170.065
regulation of system processGO:00440572080.065
lipid metabolic processGO:00066292830.064
regulation of cellular localizationGO:00603412630.064
carbohydrate derivative metabolic processGO:19011353460.064
purine ribonucleoside triphosphate catabolic processGO:00092071220.063
nucleoside catabolic processGO:00091641260.063
nucleoside triphosphate catabolic processGO:00091431230.062
nucleotide catabolic processGO:00091661390.062
transmembrane transportGO:00550854120.062
regulation of phosphorus metabolic processGO:00511743490.062
regulation of synaptic transmissionGO:00508041410.061
carboxylic acid metabolic processGO:00197522890.061
response to external biotic stimulusGO:00432072210.060
regulation of secretion by cellGO:19035302080.060
purine containing compound metabolic processGO:00725212530.059
positive regulation of signal transductionGO:00099671750.058
ribonucleoside triphosphate catabolic processGO:00092031220.058
regulation of cell motilityGO:20001451310.058
response to inorganic substanceGO:00100353770.058
reproductionGO:00000032450.058
nitrogen compound transportGO:00717052290.057
positive regulation of cytosolic calcium ion concentrationGO:00072041220.057
macromolecular complex subunit organizationGO:00439333390.056
positive regulation of phosphorus metabolic processGO:00105622620.056
cellular component biogenesisGO:00440853680.056
cytoskeleton organizationGO:00070101110.056
regulation of purine nucleotide metabolic processGO:19005421150.055
tissue developmentGO:00098882520.055
purine nucleoside metabolic processGO:00422781690.055
negative regulation of multicellular organismal processGO:00512412030.054
regulation of cell developmentGO:00602842630.054
positive regulation of developmental processGO:00510942830.054
neurological system processGO:00508772190.053
Rat
positive regulation of catalytic activityGO:00430851840.053
regulation of metal ion transportGO:00109591180.053
response to biotic stimulusGO:00096072260.052
intracellular transportGO:00469071850.051
positive regulation of cell proliferationGO:00082842490.051
response to nutrient levelsGO:00316673700.051
actin filament based processGO:0030029860.051
regulation of neuron projection developmentGO:00109751610.051
small molecule catabolic processGO:0044282590.050
regulation of phosphorylationGO:00423252480.050
organic acid metabolic processGO:00060822920.049
positive regulation of cellular component organizationGO:00511302000.049
purine ribonucleoside metabolic processGO:00461281680.049
nucleobase containing compound catabolic processGO:00346551520.049
positive regulation of phosphate metabolic processGO:00459372620.049
chemical homeostasisGO:00488782920.049
Rat
cellular response to oxygen containing compoundGO:19017013860.048
secretionGO:00469033070.047
locomotionGO:00400112370.047
localization of cellGO:00516742020.046
oxoacid metabolic processGO:00434362900.046
macromolecular complex assemblyGO:00650032730.046
response to corticosteroidGO:00319602350.045
multicellular organismal reproductive processGO:00486092330.045
metal ion homeostasisGO:00550651860.044
ribonucleoside metabolic processGO:00091191740.044
positive regulation of nitrogen compound metabolic processGO:00511733340.044
response to peptideGO:19016522920.044
Rat
positive regulation of cell differentiationGO:00455972170.043
nucleoside phosphate catabolic processGO:19012921400.043
regulation of hormone secretionGO:00468831060.043
response to molecule of bacterial originGO:00022371940.043
regulation of ion transportGO:00432692450.043
multi multicellular organism processGO:00447061380.042
protein homooligomerizationGO:0051260910.042
response to nutrientGO:00075842480.042
organic cyclic compound catabolic processGO:19013611750.042
cytosolic calcium ion homeostasisGO:00514801400.042
response to metal ionGO:00100382530.041
single organism reproductive processGO:00447022970.041
single organism intracellular transportGO:19025821660.041
cell migrationGO:00164771970.041
regulation of protein metabolic processGO:00512462890.041
positive regulation of nucleoside metabolic processGO:0045979550.040
regulation of catalytic activityGO:00507903040.040
multicellular organism reproductionGO:00325042330.040
hormone transportGO:00099141210.040
divalent metal ion transportGO:00708381320.039
regulation of neuron differentiationGO:00456642080.039
macromolecule localizationGO:00330362520.039
regulation of cellular component movementGO:00512701500.039
heart processGO:0003015570.039
response to decreased oxygen levelsGO:00362932370.038
glycosyl compound metabolic processGO:19016571820.038
action potentialGO:0001508540.038
positive regulation of secretionGO:00510471400.038
cell part morphogenesisGO:00329901230.038
organic anion transportGO:00157111320.038
ion transmembrane transportGO:00342203650.038
regulation of cell projection organizationGO:00313441750.037
response to estradiolGO:00323551640.037
regulation of anatomical structure sizeGO:00900661350.037
positive regulation of molecular functionGO:00440932300.037
positive regulation of hydrolase activityGO:0051345860.036
cellular response to endogenous stimulusGO:00714953770.036
Rat
forebrain developmentGO:0030900980.036
ras protein signal transductionGO:0007265290.036
regulation of membrane potentialGO:00423911100.036
cellular component morphogenesisGO:00329891550.036
regulation of anatomical structure morphogenesisGO:00226031410.035
protein oligomerizationGO:00512591910.035
response to alkaloidGO:00432791320.035
Rat
response to acid chemicalGO:00011012220.034
Rat
regulation of transcription dna templatedGO:00063553740.034
positive regulation of nucleobase containing compound metabolic processGO:00459353190.034
ribonucleoside catabolic processGO:00424541260.034
positive regulation of neurogenesisGO:00507691650.034
regulation of programmed cell deathGO:00430673410.034
amide transportGO:00428861050.034
regulation of purine nucleotide catabolic processGO:0033121650.034
vesicle mediated transportGO:00161921810.034
chemosensory behaviorGO:000763520.033
small gtpase mediated signal transductionGO:0007264360.033
purine ribonucleoside catabolic processGO:00461301240.033
purine nucleoside triphosphate metabolic processGO:00091441410.033
regulation of locomotionGO:00400121480.033
multi organism reproductive processGO:00447032620.033
circulatory system developmentGO:00723591340.033
regulation of rna metabolic processGO:00512523910.033
response to radiationGO:00093141370.033
cell motilityGO:00488702020.032
cellular nitrogen compound catabolic processGO:00442701630.032
positive regulation of cell developmentGO:00107201760.032
inflammatory responseGO:00069541500.032
divalent inorganic cation transportGO:00725111340.032
single organism organelle organizationGO:19025891800.032
regulation of blood vessel sizeGO:0050880890.032
neuron projection morphogenesisGO:00488121220.032
cellular response to growth factor stimulusGO:00713631620.031
response to monosaccharideGO:00342841590.031
programmed cell deathGO:00125013920.031
ribonucleoside triphosphate metabolic processGO:00091991410.031
calcium ion transportGO:00068161310.031
regulation of hydrolase activityGO:00513361430.031
positive regulation of locomotionGO:00400171020.031
cellular ketone metabolic processGO:0042180510.030
regulation of calcium ion transportGO:0051924770.030
purine nucleoside triphosphate catabolic processGO:00091461220.030
g protein coupled receptor signaling pathwayGO:00071862420.030
reproductive processGO:00224143720.030
nucleoside metabolic processGO:00091161790.029
response to growth factorGO:00708481890.029
gastrulationGO:000736920.029
defense responseGO:00069521940.029
single organism biosynthetic processGO:00447113420.028
response to estrogenGO:00436272320.028
response to cytokineGO:00340972150.028
organelle organizationGO:00069962660.028
positive regulation of cellular protein metabolic processGO:00322701670.028
purine ribonucleoside monophosphate metabolic processGO:0009167840.028
response to peptide hormoneGO:00434342780.028
Rat
calcium ion transmembrane transportGO:0070588700.027
response to carbohydrateGO:00097431830.027
cell projection morphogenesisGO:00488581230.027
tube developmentGO:0035295890.027
regulation of cellular amino acid metabolic processGO:000652120.026
positive regulation of nucleotide metabolic processGO:0045981910.026
heart morphogenesisGO:000300730.026
cellular response to hormone stimulusGO:00328702470.026
regulation of cell morphogenesis involved in differentiationGO:0010769720.026
regulation of cell morphogenesisGO:0022604770.026
negative regulation of metabolic processGO:00098923310.026
establishment of protein localizationGO:00451841410.026
olfactory learningGO:000835510.026
nucleic acid templated transcriptionGO:00976593790.025
guanosine containing compound metabolic processGO:1901068740.025
regulation of cellular protein metabolic processGO:00322682670.024
anion transportGO:00068201780.024
lipid biosynthetic processGO:00086101280.024
sexual reproductionGO:00199531480.024
neuronal action potentialGO:0019228350.024
cellular response to nitrogen compoundGO:19016992100.024
Rat
adult locomotory behaviorGO:000834440.024
multicellular organismal signalingGO:0035637440.023
heart contractionGO:0060047570.023
heart developmentGO:0007507720.023
positive regulation of nervous system developmentGO:00519621780.023
glycosyl compound catabolic processGO:19016581260.023
cellular response to organonitrogen compoundGO:00714171970.023
Rat
response to ketoneGO:19016541820.023
organic acid catabolic processGO:0016054490.023
transmission of nerve impulseGO:0019226420.023
cellular response to abiotic stimulusGO:0071214850.022
blood circulationGO:00080151830.022
regulation of nucleotide catabolic processGO:0030811650.022
positive regulation of nucleotide catabolic processGO:0030813530.022
positive regulation of protein metabolic processGO:00512471780.022
sensory perceptionGO:00076001010.022
Rat
carboxylic acid catabolic processGO:0046395490.022
cell morphogenesis involved in differentiationGO:00009041190.022
monovalent inorganic cation transportGO:00156721720.022
neuron neuron synaptic transmissionGO:0007270600.021
lipid catabolic processGO:0016042460.021
response to lipopolysaccharideGO:00324961910.021
cellular amine metabolic processGO:0044106380.021
Rat
cardiac chamber developmentGO:000320510.021
negative regulation of cellular metabolic processGO:00313242810.021
response to hexoseGO:00097461440.021
regenerationGO:00310991630.020
axis specificationGO:000979840.020
response to calcium ionGO:0051592590.020
multicellular organism growthGO:003526410.020
positive regulation of phosphorylationGO:00423271770.020
response to light stimulusGO:0009416520.020
regulation of cellular catabolic processGO:00313291010.020
negative regulation of transportGO:00510511360.020
positive regulation of secretion by cellGO:19035321280.020
regulation of transferase activityGO:00513381230.020
negative regulation of cell deathGO:00605482290.020
cell morphogenesis involved in neuron differentiationGO:00486671060.020
positive regulation of cellular component biogenesisGO:0044089550.020
positive regulation of neuron projection developmentGO:0010976990.020
negative regulation of gene expressionGO:00106291990.019
negative regulation of nervous system developmentGO:0051961790.019
regulation of cellular amine metabolic processGO:003323880.019
atp catabolic processGO:0006200540.019
regulation of nucleoside metabolic processGO:0009118660.019
mesoderm developmentGO:000749820.019
cellular lipid catabolic processGO:0044242370.019
cell morphogenesisGO:00009021420.019
positive regulation of catabolic processGO:0009896780.019
cellular response to corticosteroid stimulusGO:0071384690.019
reproductive system developmentGO:00614581280.018
response to ethanolGO:00454711620.018
Rat
positive regulation of purine nucleotide metabolic processGO:1900544910.018
amine metabolic processGO:0009308380.018
Rat
atp metabolic processGO:0046034720.018
regulation of response to stressGO:00801341260.018
muscle system processGO:00030121150.018
lipid localizationGO:0010876620.018
olfactory behaviorGO:004204820.018
regulation of protein phosphorylationGO:00019321830.018
dendrite developmentGO:0016358720.018
peptide secretionGO:0002790860.018
cellular lipid metabolic processGO:00442552080.018
positive regulation of neuron differentiationGO:00456661260.018
organ regenerationGO:00311001010.018
gtp catabolic processGO:0006184710.018
endocytosisGO:0006897840.018
regulation of cellular ketone metabolic processGO:0010565270.018
negative regulation of ion transportGO:0043271510.018
regulation of protein modification processGO:00313991940.018
protein secretionGO:0009306340.018
regulation of cell migrationGO:00303341280.018
negative regulation of nitrogen compound metabolic processGO:00511721610.017
limbic system developmentGO:0021761380.017
regulation of peptide transportGO:0090087870.017
telencephalon developmentGO:0021537620.017
nucleoside monophosphate metabolic processGO:0009123930.017
regulation of protein transportGO:0051223680.017
developmental process involved in reproductionGO:00030061590.017
positive regulation of purine nucleotide catabolic processGO:0033123530.017
organonitrogen compound biosynthetic processGO:19015661670.017
Rat
regulation of catabolic processGO:00098941130.017
protein phosphorylationGO:00064683450.017
response to purine containing compoundGO:00140741260.017
cellular response to stressGO:00335542690.017
fatty acid metabolic processGO:0006631990.017
single organism behaviorGO:00447081300.017
positive regulation of cell motilityGO:2000147970.017
gtp metabolic processGO:0046039720.017
transcription dna templatedGO:00063513770.017
negative regulation of cell proliferationGO:00082851190.016
positive regulation of apoptotic processGO:00430651540.016
actin cytoskeleton organizationGO:0030036730.016
carboxylic acid transportGO:00469421150.016
second messenger mediated signalingGO:0019932510.016
cellular amino acid metabolic processGO:00065201070.016
organic acid transportGO:00158491160.016
sequestering of metal ionGO:005123890.016
positive regulation of cellular component movementGO:00512721020.016
positive regulation of gtpase activityGO:0043547470.016
cytoplasmic transportGO:00164821150.016
regulation of cellular component biogenesisGO:0044087860.016
regulation of small gtpase mediated signal transductionGO:0051056480.016
maintenance of locationGO:0051235170.016
cellular response to cytokine stimulusGO:00713451270.016
purine nucleoside monophosphate catabolic processGO:0009128550.016
regulation of blood circulationGO:19035221100.015
peptide hormone secretionGO:0030072840.015
respiratory system developmentGO:0060541450.015
positive regulation of biosynthetic processGO:00098913190.015
neurotransmitter transportGO:0006836420.015
hormone metabolic processGO:0042445690.015
growthGO:00400071650.015
positive regulation of gene expressionGO:00106282440.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
regulation of protein kinase activityGO:00458591050.015
protein transportGO:00150311320.015
regulation of response to external stimulusGO:00321011060.015
cellular response to oxygen levelsGO:0071453600.015
amino acid transportGO:0006865700.015
regulation of tube sizeGO:0035150890.015
signal transduction by phosphorylationGO:00230141440.015
sequestering of calcium ionGO:005120880.015
epithelium developmentGO:0060429960.015
alpha amino acid metabolic processGO:1901605710.015
cellular macromolecule localizationGO:00707271220.015
positive regulation of cellular catabolic processGO:0031331710.015
vascular process in circulatory systemGO:0003018960.015
positive regulation of protein modification processGO:00314011420.015
neural crest cell differentiationGO:001403320.015
regulation of gtpase activityGO:0043087570.015
purine nucleoside monophosphate metabolic processGO:0009126840.015
proteolysisGO:00065081750.014
negative regulation of cell communicationGO:00106481580.014
positive regulation of corticosteroid hormone secretionGO:200084840.014
protein heterooligomerizationGO:0051291890.014
positive regulation of cytoskeleton organizationGO:0051495260.014
regulation of cell growthGO:0001558850.014
response to glucoseGO:00097491360.014
female pregnancyGO:00075651220.014
wound healingGO:00420601220.014
acute inflammatory responseGO:0002526580.014
regulation of lipid metabolic processGO:0019216680.014
positive regulation of protein kinase activityGO:0045860730.014
neural crest cell developmentGO:001403220.014
peptide transportGO:0015833970.014
regulation of kinase activityGO:00435491170.014
transcription from rna polymerase ii promoterGO:00063662520.014
axonogenesisGO:0007409710.014
regulation of establishment of protein localizationGO:0070201690.014
nucleoside monophosphate catabolic processGO:0009125560.014
positive regulation of cellular amine metabolic processGO:003324030.013
steroid metabolic processGO:0008202730.013
ribonucleoside monophosphate metabolic processGO:0009161880.013
cardiovascular system developmentGO:00723581340.013
positive regulation of cell projection organizationGO:00313461110.013
calcium ion importGO:0070509220.013
behaviorGO:00076102050.013
Rat
membrane organizationGO:0061024940.013
positive regulation of programmed cell deathGO:00430681570.013
negative regulation of neurogenesisGO:0050768780.013
camp metabolic processGO:0046058630.013
axon developmentGO:0061564960.013
purine containing compound biosynthetic processGO:0072522850.013
cardiac ventricle developmentGO:000323110.013
cell growthGO:00160491040.013
insulin secretionGO:0030073690.013
regulation of peptide hormone secretionGO:0090276800.013
pallium developmentGO:0021543420.013
organic hydroxy compound transportGO:0015850770.013
organophosphate biosynthetic processGO:00904071430.013
rho protein signal transductionGO:0007266110.013
receptor mediated endocytosisGO:0006898420.013
ribonucleoside monophosphate catabolic processGO:0009158550.013
response to nicotineGO:0035094510.013
Rat
potassium ion transportGO:0006813970.013
ensheathment of neuronsGO:0007272400.013
agingGO:00075682410.013
Rat
cyclic nucleotide metabolic processGO:0009187800.013
negative regulation of developmental processGO:00510931250.013
regulation of response to woundingGO:1903034690.013
cellular protein localizationGO:00346131220.013
cellular response to lipidGO:00713962010.012
ossificationGO:0001503700.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
regulation of neurotransmitter levelsGO:0001505420.012
Rat
muscle contractionGO:0006936880.012
negative regulation of biosynthetic processGO:00098901680.012
regulation of muscle contractionGO:0006937530.012
negative regulation of macromolecule metabolic processGO:00106052600.012
actin filament depolymerizationGO:003004230.012
reactive nitrogen species metabolic processGO:200105710.012
muscle cell proliferationGO:0033002840.012
glucose homeostasisGO:0042593750.012
Rat
anterior posterior pattern specificationGO:000995210.012
actin filament organizationGO:0007015420.012
regulation of body fluid levelsGO:0050878900.012
mapk cascadeGO:00001651400.012
positive regulation of mapk cascadeGO:0043410920.012
jak stat cascadeGO:0007259260.012
reproductive structure developmentGO:00486081280.012
negative regulation of molecular functionGO:00440921330.012
positive regulation of cell deathGO:00109421840.012
regulation of smooth muscle cell proliferationGO:0048660750.012
regulation of ras protein signal transductionGO:0046578450.012
monocarboxylic acid transportGO:0015718520.012
cellular modified amino acid metabolic processGO:0006575610.012
sensory organ developmentGO:0007423740.012
gliogenesisGO:0042063930.012
positive regulation of calcium ion transportGO:0051928360.011
actin mediated cell contractionGO:0070252120.011
reactive oxygen species metabolic processGO:0072593370.011
choline transportGO:001587140.011
cytokine mediated signaling pathwayGO:0019221430.011
positive regulation of smooth muscle cell proliferationGO:0048661510.011
organic acid biosynthetic processGO:0016053830.011
regulation of axon extensionGO:0030516240.011
response to oxidative stressGO:00069791860.011
Rat
regulation of gtp catabolic processGO:0033124580.011
negative regulation of secretionGO:0051048820.011
organ morphogenesisGO:0009887750.011
rhythmic processGO:00485111560.011

Pam disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.045
musculoskeletal system diseaseDOID:1700.030
muscular diseaseDOID:008000000.015
muscle tissue diseaseDOID:6600.015
central nervous system diseaseDOID:33100.014
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.013
sensory system diseaseDOID:005015500.013