Rattus norvegicus

80 known processes

Slit2

slit homolog 2 (Drosophila)

Slit2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.204
metal ion transportGO:00300012890.180
ion transmembrane transportGO:00342203650.178
inorganic cation transmembrane transportGO:00986622020.129
cation transportGO:00068123820.129
inorganic ion transmembrane transportGO:00986602290.106
cation transmembrane transportGO:00986552630.096
regulation of ion transportGO:00432692450.092
calcium ion transmembrane transportGO:0070588700.071
muscle system processGO:00030121150.070
positive regulation of cell proliferationGO:00082842490.068
vesicle mediated transportGO:00161921810.067
carboxylic acid metabolic processGO:00197522890.067
homeostatic processGO:00425923310.067
calcium ion transportGO:00068161310.067
secretionGO:00469033070.065
behaviorGO:00076102050.062
biological adhesionGO:00226101100.061
Mouse Fly
regulation of secretion by cellGO:19035302080.061
monovalent inorganic cation transportGO:00156721720.059
regulation of vesicle mediated transportGO:0060627810.057
neuron differentiationGO:00301823680.056
Human Zebrafish Mouse Rat Fly
programmed cell deathGO:00125013920.056
Human
regulation of transmembrane transportGO:00347621220.055
cellular metal ion homeostasisGO:00068751720.055
negative regulation of cell deathGO:00605482290.054
regulation of hormone levelsGO:00108171870.053
development of primary sexual characteristicsGO:00451371070.047
Human Fly
divalent metal ion transportGO:00708381320.046
regulation of molecular functionGO:00650093980.046
Human
growthGO:00400071650.045
Human Zebrafish Mouse Rat
positive regulation of multicellular organismal processGO:00512403870.045
regulation of phosphorus metabolic processGO:00511743490.044
Human
neurological system processGO:00508772190.044
cellular ion homeostasisGO:00068731840.044
organic anion transportGO:00157111320.044
brain developmentGO:00074202470.042
positive regulation of transportGO:00510502450.040
response to nutrient levelsGO:00316673700.040
protein localizationGO:00081041910.040
cellular calcium ion homeostasisGO:00068741600.040
cellular divalent inorganic cation homeostasisGO:00725031620.040
regulation of protein metabolic processGO:00512462890.040
Human
organic acid metabolic processGO:00060822920.038
kidney developmentGO:0001822670.038
Human Mouse
regulation of cell proliferationGO:00421273590.037
Mouse
cell projection organizationGO:00300303020.037
Human Zebrafish Mouse Rat Fly
sex differentiationGO:00075481130.036
Human Fly
embryonic appendage morphogenesisGO:003511340.036
tube developmentGO:0035295890.036
Human Mouse Fly
cell part morphogenesisGO:00329901230.036
Human Zebrafish Mouse Rat Fly
positive regulation of molecular functionGO:00440932300.036
regulation of system processGO:00440572080.035
protein complex subunit organizationGO:00718223020.034
Human
development of primary female sexual characteristicsGO:0046545560.033
Human
calcium ion homeostasisGO:00550741620.033
tissue developmentGO:00098882520.033
Human Zebrafish Mouse Fly
single organism reproductive processGO:00447022970.033
Human Fly
cellular component biogenesisGO:00440853680.033
Human
heart morphogenesisGO:000300730.032
Zebrafish Fly
cellular amine metabolic processGO:0044106380.032
multi organism reproductive processGO:00447032620.032
head developmentGO:00603222470.031
axon choice point recognitionGO:001619820.031
Fly
female gonad developmentGO:0008585530.031
Human
regulation of multicellular organismal developmentGO:20000263760.031
Human Zebrafish Mouse Rat Fly
divalent inorganic cation transportGO:00725111340.031
negative regulation of multicellular organismal processGO:00512412030.031
Human Zebrafish Mouse Rat
central nervous system developmentGO:00074173110.031
divalent inorganic cation homeostasisGO:00725071650.031
intracellular transportGO:00469071850.030
ion homeostasisGO:00508012120.030
forebrain developmentGO:0030900980.030
Human Mouse
response to extracellular stimulusGO:00099913800.029
secretion by cellGO:00329402480.029
gland developmentGO:00487321550.029
Mouse Fly
positive regulation of phosphate metabolic processGO:00459372620.028
cellular amino acid metabolic processGO:00065201070.028
regulation of cell migrationGO:00303341280.028
cellular component assemblyGO:00226073600.027
Human
renal system developmentGO:0072001670.027
Human Mouse
learningGO:0007612330.027
macromolecular complex assemblyGO:00650032730.027
Human
regulation of metal ion transportGO:00109591180.027
regulation of intracellular signal transductionGO:19025312180.027
Human
response to ketoneGO:19016541820.027
Human
salivary gland developmentGO:000743130.027
Fly
regulation of secretionGO:00510462240.027
cell morphogenesis involved in differentiationGO:00009041190.026
Human Zebrafish Mouse Rat Fly
regulation of nervous system developmentGO:00519602640.026
Human Zebrafish Mouse Rat
positive regulation of secretionGO:00510471400.026
single organism biosynthetic processGO:00447113420.026
protein oligomerizationGO:00512591910.026
regulation of cellular amine metabolic processGO:003323880.026
regulation of transmembrane transporter activityGO:0022898490.026
positive regulation of nitrogen compound metabolic processGO:00511733340.026
response to estrogenGO:00436272320.026
regulation of phosphate metabolic processGO:00192203490.025
Human
cation homeostasisGO:00550801950.025
regulation of cellular amino acid metabolic processGO:000652120.025
regulation of ion transmembrane transportGO:00347651210.025
learning or memoryGO:0007611900.025
cell adhesionGO:00071551100.025
Mouse Fly
response to oxygen levelsGO:00704822650.025
response to ethanolGO:00454711620.024
macromolecule localizationGO:00330362520.024
ossificationGO:0001503700.024
carbohydrate metabolic processGO:00059751300.024
intracellular signal transductionGO:00355563140.024
Human
locomotionGO:00400112370.024
multicellular organismal reproductive processGO:00486092330.024
Human
rhythmic processGO:00485111560.024
Human
single organism organelle organizationGO:19025891800.024
Human
neuron projection developmentGO:00311752730.023
Human Zebrafish Mouse Rat Fly
regulation of catalytic activityGO:00507903040.023
Human
proteolysisGO:00065081750.023
negative regulation of cell communicationGO:00106481580.023
Human
cellular response to endogenous stimulusGO:00714953770.023
Human
cellular chemical homeostasisGO:00550822470.022
ovulation cycleGO:0042698670.022
Human
positive regulation of phosphorus metabolic processGO:00105622620.022
regulation of transporter activityGO:0032409500.022
positive regulation of biosynthetic processGO:00098913190.022
reproductive system developmentGO:00614581280.022
Human Fly
regulation of cellular ketone metabolic processGO:0010565270.022
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633930.022
response to estradiolGO:00323551640.021
response to radiationGO:00093141370.021
regulation of cellular localizationGO:00603412630.021
anion transportGO:00068201780.021
response to glucocorticoidGO:00513842230.021
Human
positive regulation of cell communicationGO:00106472710.021
developmental growthGO:00485891000.021
Human Zebrafish Mouse Rat
regulation of protein modification processGO:00313991940.021
Human
hormone metabolic processGO:0042445690.021
positive regulation of cytosolic calcium ion concentrationGO:00072041220.021
cellular component morphogenesisGO:00329891550.020
Human Zebrafish Mouse Rat Fly
regulation of neurogenesisGO:00507672470.020
Human Zebrafish Mouse Rat
sodium ion transportGO:0006814820.020
epithelial cell proliferationGO:0050673540.020
prostate gland epithelium morphogenesisGO:006074020.020
nucleoside phosphate metabolic processGO:00067532830.020
Human
chemosensory behaviorGO:000763520.020
positive regulation of cellular biosynthetic processGO:00313282950.020
g protein coupled receptor signaling pathwayGO:00071862420.020
cellular homeostasisGO:00197252520.020
regulation of programmed cell deathGO:00430673410.020
Human
apoptotic processGO:00069153810.020
Human
gastrulationGO:000736920.020
Fly
protein complex biogenesisGO:00702712630.020
Human
salivary gland morphogenesisGO:000743510.020
blood circulationGO:00080151830.020
Human
single organism behaviorGO:00447081300.019
receptor metabolic processGO:0043112180.019
metal ion homeostasisGO:00550651860.019
macromolecular complex subunit organizationGO:00439333390.019
Human
positive regulation of cellular component organizationGO:00511302000.019
response to corticosteroidGO:00319602350.019
Human
circadian rhythmGO:0007623880.019
single organism carbohydrate metabolic processGO:00447231180.019
regulation of phosphorylationGO:00423252480.019
Human
cellular ketone metabolic processGO:0042180510.019
organ morphogenesisGO:0009887750.019
Zebrafish Mouse Fly
negative regulation of programmed cell deathGO:00430691830.019
sequestering of calcium ionGO:005120880.019
agingGO:00075682410.019
nucleobase containing small molecule metabolic processGO:00550863160.019
Human
regulation of g0 to g1 transitionGO:007031630.019
olfactory behaviorGO:004204820.019
organonitrogen compound biosynthetic processGO:19015661670.019
muscle contractionGO:0006936880.019
appendage morphogenesisGO:003510740.019
nucleotide metabolic processGO:00091172790.018
Human
sequestering of metal ionGO:005123890.018
regulation of ion transmembrane transporter activityGO:0032412480.018
female sex differentiationGO:0046660590.018
Human
organic hydroxy compound transportGO:0015850770.018
cellular response to hormone stimulusGO:00328702470.018
Human
monosaccharide metabolic processGO:0005996610.018
cell cell signalingGO:00072673350.018
Fly
carbohydrate derivative metabolic processGO:19011353460.018
Human
cerebral cortex tangential migrationGO:002180010.018
Human
organophosphate metabolic processGO:00196373700.018
Human
cell morphogenesisGO:00009021420.018
Human Zebrafish Mouse Rat Fly
regulation of hydrolase activityGO:00513361430.018
small gtpase mediated signal transductionGO:0007264360.017
Human
multicellular organismal signalingGO:0035637440.017
cellular response to growth factor stimulusGO:00713631620.017
Human
single organism intracellular transportGO:19025821660.017
gonad developmentGO:00084061040.017
Human Fly
negative regulation of metabolic processGO:00098923310.017
Human Mouse
response to decreased oxygen levelsGO:00362932370.017
urogenital system developmentGO:0001655780.017
Human Mouse
positive regulation of cell developmentGO:00107201760.017
positive regulation of locomotionGO:00400171020.017
Human Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353190.017
cytosolic calcium ion homeostasisGO:00514801400.017
olfactory learningGO:000835510.017
negative regulation of macromolecule metabolic processGO:00106052600.017
Human Mouse
regulation of cellular component movementGO:00512701500.017
cellular cation homeostasisGO:00300031800.017
regulation of peptide secretionGO:0002791820.017
nucleic acid templated transcriptionGO:00976593790.017
male sex differentiationGO:0046661640.016
reproductive processGO:00224143720.016
Human Fly
positive regulation of rna biosynthetic processGO:19026801970.016
response to metal ionGO:00100382530.016
cytoskeleton organizationGO:00070101110.016
Human
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.016
peptidyl amino acid modificationGO:00181931260.016
single organism catabolic processGO:00447122830.016
Human
cellular response to lipidGO:00713962010.016
purine ribonucleotide metabolic processGO:00091502270.016
Human
regulation of purine nucleotide metabolic processGO:19005421150.016
chemical homeostasisGO:00488782920.016
oxoacid metabolic processGO:00434362900.016
catabolic processGO:00090563510.016
Human
regulation of growthGO:00400081050.016
Human Zebrafish Mouse Rat
cognitionGO:0050890920.016
positive regulation of cell differentiationGO:00455972170.016
chemotaxisGO:0006935660.016
response to carbohydrateGO:00097431830.015
negative regulation of cellular metabolic processGO:00313242810.015
Human
positive regulation of long term synaptic potentiationGO:190027340.015
dendrite developmentGO:0016358720.015
Fly
cellular response to oxygen containing compoundGO:19017013860.015
Human
cytoplasmic transportGO:00164821150.015
cellular response to steroid hormone stimulusGO:0071383930.015
ribose phosphate metabolic processGO:00196932350.015
Human
organ formationGO:004864530.015
Zebrafish Fly
positive regulation of signalingGO:00230562700.015
reproductionGO:00000032450.015
Human
epithelium developmentGO:0060429960.015
Human Zebrafish Mouse Fly
steroid metabolic processGO:0008202730.014
cellular response to organic cyclic compoundGO:00714072020.014
purine containing compound metabolic processGO:00725212530.014
Human
reproductive structure developmentGO:00486081280.014
Human Fly
cell fate determinationGO:000170920.014
regulation of cellular component organizationGO:00511283680.014
Human Zebrafish Mouse Rat
regulation of cardiac muscle contractionGO:0055117170.014
cellular response to stressGO:00335542690.014
response to oxidative stressGO:00069791860.014
regulation of anatomical structure sizeGO:00900661350.014
Human Zebrafish Mouse Rat
endoplasmic reticulum to cytosol transportGO:190351340.014
respiratory system developmentGO:0060541450.014
Fly
positive regulation of developmental processGO:00510942830.014
endocytosisGO:0006897840.014
cell motilityGO:00488702020.014
response to hypoxiaGO:00016662310.014
response to nutrientGO:00075842480.014
regulation of proteasomal protein catabolic processGO:006113640.014
eye morphogenesisGO:004859240.014
nitrogen compound transportGO:00717052290.014
ras protein signal transductionGO:0007265290.014
response to vitaminGO:00332731310.014
localization of cellGO:00516742020.014
prostate gland morphogenesisGO:006051220.014
positive regulation of transcription dna templatedGO:00458931970.014
lipid metabolic processGO:00066292830.013
regulation of nucleotide metabolic processGO:00061401170.013
response to acid chemicalGO:00011012220.013
negative regulation of apoptotic processGO:00430661810.013
negative regulation of developmental processGO:00510931250.013
Human Zebrafish Mouse Rat
sexual reproductionGO:00199531480.013
cellular response to external stimulusGO:00714961180.013
response to inorganic substanceGO:00100353770.013
positive regulation of gene expressionGO:00106282440.013
positive regulation of secretion by cellGO:19035321280.013
associative learningGO:0008306190.013
muscle structure developmentGO:0061061870.013
motor neuron axon guidanceGO:000804510.013
Human
calcium ion importGO:0070509220.013
regulation of neuron differentiationGO:00456642080.013
Human Zebrafish Mouse Rat
positive regulation of neurogenesisGO:00507691650.013
cellular response to alcoholGO:0097306870.013
amine metabolic processGO:0009308380.013
negative regulation of signalingGO:00230571570.013
Human
positive regulation of nucleoside metabolic processGO:0045979550.013
regulation of calcium ion transportGO:0051924770.013
positive regulation of ion transmembrane transportGO:0034767240.013
limb morphogenesisGO:003510840.013
response to growth factorGO:00708481890.013
Human
regulation of stem cell differentiationGO:200073620.012
multi multicellular organism processGO:00447061380.012
cellular macromolecule localizationGO:00707271220.012
maintenance of locationGO:0051235170.012
neuron projection morphogenesisGO:00488121220.012
Human Zebrafish Mouse Rat Fly
signal releaseGO:00230611450.012
cell migrationGO:00164771970.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
positive regulation of nucleotide metabolic processGO:0045981910.012
circulatory system processGO:00030131830.012
Human
axis specificationGO:000979840.012
embryonic pattern specificationGO:000988010.012
anatomical structure morphogenesisGO:00096532980.012
Human Zebrafish Mouse Rat Fly
protein phosphorylationGO:00064683450.012
Human
single organism cellular localizationGO:19025801020.012
neuron fate commitmentGO:004866340.012
purine ribonucleoside catabolic processGO:00461301240.012
Human
circulatory system developmentGO:00723591340.012
Human Zebrafish Fly
response to cocaineGO:0042220390.012
cell projection morphogenesisGO:00488581230.012
Human Zebrafish Mouse Rat Fly
regulation of blood vessel sizeGO:0050880890.012
olfactory bulb interneuron differentiationGO:002188910.012
Human
monoamine transportGO:0015844430.012
positive regulation of epithelial cell proliferationGO:0050679320.012
organic acid transportGO:00158491160.012
cellular component movementGO:00069282480.012
single organismal cell cell adhesionGO:0016337420.012
Mouse Fly
positive regulation of rna metabolic processGO:00512542030.012
positive regulation of signal transductionGO:00099671750.012
regulation of transcription dna templatedGO:00063553740.012
regulation of cell growthGO:0001558850.012
Human Zebrafish Mouse Rat
purine nucleotide metabolic processGO:00061632290.012
Human
rho protein signal transductionGO:0007266110.012
protein complex assemblyGO:00064612630.012
Human
regulation of striated muscle contractionGO:0006942210.011
purine nucleoside metabolic processGO:00422781690.011
Human
taxisGO:0042330670.011
ribonucleotide metabolic processGO:00092592310.011
Human
negative regulation of response to stimulusGO:00485851550.011
action potentialGO:0001508540.011
alcohol metabolic processGO:0006066770.011
response to monosaccharideGO:00342841590.011
exocytosisGO:0006887600.011
regulation of protein phosphorylationGO:00019321830.011
Human
vascular process in circulatory systemGO:0003018960.011
Human
neuron developmentGO:00486662860.011
Human Zebrafish Mouse Rat Fly
regulation of b cell differentiationGO:004557710.011
response to calcium ionGO:0051592590.011
ovulation cycle processGO:0022602500.011
Human
regulation of rna metabolic processGO:00512523910.011
axon midline choice point recognitionGO:001619920.011
Fly
regulation of membrane potentialGO:00423911100.011
regulation of muscle system processGO:0090257790.011
lung developmentGO:0030324430.011
respiratory gaseous exchangeGO:000758540.011
response to molecule of bacterial originGO:00022371940.011
regulation of developmental growthGO:0048638450.011
Zebrafish Mouse Rat
transcription from rna polymerase ii promoterGO:00063662520.011
membrane hyperpolarizationGO:0060081110.011
regulation of homeostatic processGO:00328441010.011
response to light stimulusGO:0009416520.011
erythrocyte differentiationGO:003021810.011
regulation of epithelial cell proliferationGO:0050678490.011
cellular catabolic processGO:00442482950.011
Human
cell morphogenesis involved in neuron differentiationGO:00486671060.010
Human Zebrafish Mouse Rat Fly
response to glucoseGO:00097491360.010
lipid transportGO:0006869610.010
sensory organ developmentGO:0007423740.010
organelle organizationGO:00069962660.010
Human
regulation of peptide transportGO:0090087870.010
positive regulation of cellular amine metabolic processGO:003324030.010
negative regulation of neuron differentiationGO:0045665620.010
Human Zebrafish Mouse Rat
cellular carbohydrate metabolic processGO:0044262720.010
response to electrical stimulusGO:0051602560.010
developmental process involved in reproductionGO:00030061590.010
Human Fly
regulation of tube sizeGO:0035150890.010
calcium ion transport into cytosolGO:0060402380.010
protein tetramerizationGO:0051262380.010
synapse organizationGO:0050808460.010
organophosphate biosynthetic processGO:00904071430.010
negative regulation of growthGO:0045926370.010
Human Zebrafish Mouse Rat
n methyl d aspartate receptor clusteringGO:009711420.010

Slit2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
urinary system diseaseDOID:1800.030
nervous system diseaseDOID:86300.023
cardiovascular system diseaseDOID:128700.019
vascular diseaseDOID:17800.019
hypertensionDOID:1076300.013
artery diseaseDOID:005082800.013
musculoskeletal system diseaseDOID:1700.012
central nervous system diseaseDOID:33100.012