Rattus norvegicus

24 known processes

Sigmar1

sigma non-opioid intracellular receptor 1

(Aliases: Oprs1)

Sigmar1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442552080.249
lipid metabolic processGO:00066292830.190
oxoacid metabolic processGO:00434362900.118
organic acid metabolic processGO:00060822920.096
small molecule biosynthetic processGO:00442831240.090
carboxylic acid metabolic processGO:00197522890.086
regulation of cellular component organizationGO:00511283680.082
single organism biosynthetic processGO:00447113420.075
agingGO:00075682410.072
response to peptideGO:19016522920.072
negative regulation of metabolic processGO:00098923310.068
reproductive processGO:00224143720.066
response to inorganic substanceGO:00100353770.064
response to peptide hormoneGO:00434342780.061
lipid biosynthetic processGO:00086101280.059
neuron differentiationGO:00301823680.058
organic substance catabolic processGO:19015753160.056
cation transportGO:00068123820.056
programmed cell deathGO:00125013920.056
response to nutrient levelsGO:00316673700.055
single organism reproductive processGO:00447022970.049
negative regulation of cellular metabolic processGO:00313242810.049
rna biosynthetic processGO:00327743800.049
brain developmentGO:00074202470.048
carbohydrate derivative metabolic processGO:19011353460.048
secretion by cellGO:00329402480.047
negative regulation of macromolecule metabolic processGO:00106052600.046
central nervous system developmentGO:00074173110.044
cellular component movementGO:00069282480.044
multicellular organismal reproductive processGO:00486092330.043
head developmentGO:00603222470.042
regulation of apoptotic processGO:00429813350.041
regulation of molecular functionGO:00650093980.041
cellular response to lipidGO:00713962010.041
response to purine containing compoundGO:00140741260.040
regulation of neuron differentiationGO:00456642080.040
response to estrogenGO:00436272320.039
organophosphate metabolic processGO:00196373700.039
regulation of phosphorus metabolic processGO:00511743490.037
neurological system processGO:00508772190.037
intracellular signal transductionGO:00355563140.037
transcription dna templatedGO:00063513770.036
negative regulation of apoptotic processGO:00430661810.036
cellular response to oxygen containing compoundGO:19017013860.036
response to extracellular stimulusGO:00099913800.036
immune system processGO:00023762040.035
multicellular organism reproductionGO:00325042330.035
apoptotic processGO:00069153810.035
regulation of nucleic acid templated transcriptionGO:19035063800.035
positive regulation of transportGO:00510502450.034
regulation of transcription dna templatedGO:00063553740.034
regulation of protein metabolic processGO:00512462890.034
positive regulation of biosynthetic processGO:00098913190.034
single organism catabolic processGO:00447122830.034
amine metabolic processGO:0009308380.034
regulation of cell differentiationGO:00455953200.033
response to nutrientGO:00075842480.033
regulation of programmed cell deathGO:00430673410.033
regulation of cellular localizationGO:00603412630.033
negative regulation of cell deathGO:00605482290.033
cellular component biogenesisGO:00440853680.032
response to biotic stimulusGO:00096072260.032
muscle structure developmentGO:0061061870.032
regulation of cell developmentGO:00602842630.032
cell cell signalingGO:00072673350.031
phospholipid metabolic processGO:0006644610.031
reproductionGO:00000032450.031
organic hydroxy compound metabolic processGO:19016151150.031
positive regulation of nitrogen compound metabolic processGO:00511733340.031
secretionGO:00469033070.031
neuron projection developmentGO:00311752730.031
regulation of phosphate metabolic processGO:00192203490.031
regulation of catalytic activityGO:00507903040.030
multi organism reproductive processGO:00447032620.030
metal ion transportGO:00300012890.030
response to woundingGO:00096112540.030
behaviorGO:00076102050.029
cellular response to stressGO:00335542690.029
cellular response to endogenous stimulusGO:00714953770.029
neuron developmentGO:00486662860.029
regulation of cellular protein metabolic processGO:00322682670.029
regulation of cell growthGO:0001558850.029
protein phosphorylationGO:00064683450.029
catabolic processGO:00090563510.028
response to metal ionGO:00100382530.028
isoprenoid metabolic processGO:0006720450.028
synaptic transmissionGO:00072682350.028
regulation of synaptic transmissionGO:00508041410.028
organophosphate biosynthetic processGO:00904071430.027
chemical homeostasisGO:00488782920.027
growthGO:00400071650.027
cell growthGO:00160491040.027
circulatory system processGO:00030131830.026
homeostatic processGO:00425923310.026
organonitrogen compound biosynthetic processGO:19015661670.026
cell projection organizationGO:00300303020.026
cellular response to cytokine stimulusGO:00713451270.026
regulation of secretionGO:00510462240.026
response to vitaminGO:00332731310.026
regulation of multicellular organismal developmentGO:20000263760.026
ion homeostasisGO:00508012120.026
cation homeostasisGO:00550801950.025
cellular amine metabolic processGO:0044106380.025
negative regulation of programmed cell deathGO:00430691830.025
cellular amino acid metabolic processGO:00065201070.025
response to external biotic stimulusGO:00432072210.025
positive regulation of multicellular organismal processGO:00512403870.025
defense responseGO:00069521940.025
positive regulation of response to stimulusGO:00485842850.025
regulation of intracellular signal transductionGO:19025312180.025
tissue developmentGO:00098882520.024
positive regulation of phosphate metabolic processGO:00459372620.024
cell motilityGO:00488702020.024
alcohol metabolic processGO:0006066770.024
positive regulation of cell differentiationGO:00455972170.024
regulation of system processGO:00440572080.024
small gtpase mediated signal transductionGO:0007264360.024
sexual reproductionGO:00199531480.024
negative regulation of protein metabolic processGO:00512481140.024
cellular response to organic cyclic compoundGO:00714072020.024
rna metabolic processGO:00160704060.023
eye morphogenesisGO:004859240.023
monocarboxylic acid metabolic processGO:00327871520.023
reproductive structure developmentGO:00486081280.023
nucleic acid templated transcriptionGO:00976593790.023
response to bacteriumGO:00096172000.023
gamete generationGO:00072761240.023
gland developmentGO:00487321550.023
regulation of cell projection organizationGO:00313441750.022
cellular catabolic processGO:00442482950.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.022
regulation of hormone levelsGO:00108171870.022
cellular component assemblyGO:00226073600.022
regulation of rna biosynthetic processGO:20011413810.022
metal ion homeostasisGO:00550651860.022
inflammatory responseGO:00069541500.022
circulatory system developmentGO:00723591340.022
response to corticosteroidGO:00319602350.022
locomotionGO:00400112370.021
blood circulationGO:00080151830.021
regulation of nervous system developmentGO:00519602640.021
neuron deathGO:00709971270.021
carboxylic acid biosynthetic processGO:0046394830.021
spermatogenesisGO:0007283990.021
cellular calcium ion homeostasisGO:00068741600.021
anatomical structure morphogenesisGO:00096532980.021
heart morphogenesisGO:000300730.021
positive regulation of cellular biosynthetic processGO:00313282950.021
regulation of rna metabolic processGO:00512523910.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
cellular homeostasisGO:00197252520.020
response to molecule of bacterial originGO:00022371940.020
organic acid transportGO:00158491160.020
protein complex biogenesisGO:00702712630.020
nitrogen compound transportGO:00717052290.020
organic acid biosynthetic processGO:0016053830.020
positive regulation of phosphorus metabolic processGO:00105622620.020
developmental process involved in reproductionGO:00030061590.020
carboxylic acid transportGO:00469421150.020
negative regulation of signalingGO:00230571570.020
regulation of neuron projection developmentGO:00109751610.019
cell migrationGO:00164771970.019
regulation of cell proliferationGO:00421273590.019
rhythmic processGO:00485111560.019
regulation of secretion by cellGO:19035302080.019
ribose phosphate metabolic processGO:00196932350.019
positive regulation of cell proliferationGO:00082842490.019
response to estradiolGO:00323551640.018
regulation of cell migrationGO:00303341280.018
regulation of vesicle mediated transportGO:0060627810.018
cellular metal ion homeostasisGO:00068751720.018
positive regulation of cellular component organizationGO:00511302000.018
cellular chemical homeostasisGO:00550822470.018
cellular response to hormone stimulusGO:00328702470.018
cellular ketone metabolic processGO:0042180510.018
male gamete generationGO:0048232990.018
cellular response to nitrogen compoundGO:19016992100.018
regulation of blood pressureGO:0008217830.018
protein complex subunit organizationGO:00718223020.018
regulation of lipid metabolic processGO:0019216680.018
regulation of cellular amine metabolic processGO:003323880.017
regulation of neurogenesisGO:00507672470.017
single organism carbohydrate metabolic processGO:00447231180.017
synaptic vesicle endocytosisGO:004848840.017
negative regulation of cellular biosynthetic processGO:00313271610.017
positive regulation of cellular amine metabolic processGO:003324030.017
response to campGO:0051591910.017
response to ketoneGO:19016541820.017
localization of cellGO:00516742020.017
alpha amino acid metabolic processGO:1901605710.017
response to radiationGO:00093141370.017
regulation of growthGO:00400081050.017
organelle organizationGO:00069962660.017
ion transmembrane transportGO:00342203650.017
response to hypoxiaGO:00016662310.017
response to cytokineGO:00340972150.017
heterocycle catabolic processGO:00467001670.017
negative regulation of biosynthetic processGO:00098901680.017
ribonucleotide metabolic processGO:00092592310.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
regulation of cellular amino acid metabolic processGO:000652120.016
regenerationGO:00310991630.016
g protein coupled receptor signaling pathwayGO:00071862420.016
organic anion transportGO:00157111320.016
anion transportGO:00068201780.016
intracellular transportGO:00469071850.016
regulation of ion transportGO:00432692450.016
heart developmentGO:0007507720.016
macromolecular complex subunit organizationGO:00439333390.016
positive regulation of rna biosynthetic processGO:19026801970.016
response to decreased oxygen levelsGO:00362932370.016
fatty acid metabolic processGO:0006631990.016
purine nucleoside metabolic processGO:00422781690.016
cell type specific apoptotic processGO:00972851340.016
inorganic ion transmembrane transportGO:00986602290.016
nucleobase containing small molecule metabolic processGO:00550863160.016
ras protein signal transductionGO:0007265290.016
regulation of protein modification processGO:00313991940.016
negative regulation of response to stimulusGO:00485851550.016
positive regulation of apoptotic processGO:00430651540.015
carbohydrate metabolic processGO:00059751300.015
positive regulation of rna metabolic processGO:00512542030.015
cell adhesionGO:00071551100.015
positive regulation of developmental processGO:00510942830.015
organophosphate catabolic processGO:00464341480.015
retina morphogenesis in camera type eyeGO:006004210.015
acute inflammatory responseGO:0002526580.015
response to other organismGO:00517072200.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
regulation of hormone secretionGO:00468831060.015
cellular nitrogen compound catabolic processGO:00442701630.015
cellular cation homeostasisGO:00300031800.015
positive regulation of intracellular signal transductionGO:19025331380.015
positive regulation of phosphorylationGO:00423271770.015
carbohydrate derivative biosynthetic processGO:19011371240.015
regulation of cellular ketone metabolic processGO:0010565270.015
sulfur compound metabolic processGO:0006790700.015
steroid metabolic processGO:0008202730.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
reproductive system developmentGO:00614581280.015
nucleoside phosphate metabolic processGO:00067532830.014
regulation of signal transductionGO:00099663180.014
response to acid chemicalGO:00011012220.014
regulation of protein phosphorylationGO:00019321830.014
cofactor metabolic processGO:0051186950.014
negative regulation of transportGO:00510511360.014
negative regulation of cellular protein metabolic processGO:00322691060.014
coenzyme metabolic processGO:0006732860.014
nucleotide metabolic processGO:00091172790.014
purine nucleoside triphosphate catabolic processGO:00091461220.014
regulation of phosphorylationGO:00423252480.014
response to lipopolysaccharideGO:00324961910.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
response to temperature stimulusGO:0009266940.014
positive regulation of secretion by cellGO:19035321280.014
regulation of kinase activityGO:00435491170.014
regulation of neuron apoptotic processGO:0043523830.014
mapk cascadeGO:00001651400.014
response to alkaloidGO:00432791320.014
negative regulation of rna biosynthetic processGO:19026791180.014
negative regulation of molecular functionGO:00440921330.014
cation transmembrane transportGO:00986552630.014
response to oxidative stressGO:00069791860.014
positive regulation of transcription dna templatedGO:00458931970.014
endocytosisGO:0006897840.014
ribonucleoside monophosphate metabolic processGO:0009161880.014
purine containing compound metabolic processGO:00725212530.014
organonitrogen compound catabolic processGO:19015651790.014
response to growth factorGO:00708481890.013
regulation of homeostatic processGO:00328441010.013
aromatic compound catabolic processGO:00194391680.013
dephosphorylationGO:0016311980.013
circadian rhythmGO:0007623880.013
transmembrane transportGO:00550854120.013
muscle organ developmentGO:0007517500.013
regulation of cellular component movementGO:00512701500.013
response to oxygen levelsGO:00704822650.013
positive regulation of molecular functionGO:00440932300.013
alpha amino acid biosynthetic processGO:1901607230.013
adult locomotory behaviorGO:000834440.013
response to glucocorticoidGO:00513842230.013
response to hexoseGO:00097461440.013
synaptic growth at neuromuscular junctionGO:005112410.013
potassium ion transportGO:0006813970.013
monocarboxylic acid biosynthetic processGO:0072330480.013
regulation of protein kinase activityGO:00458591050.013
steroid biosynthetic processGO:0006694480.013
biological adhesionGO:00226101100.013
camera type eye developmentGO:0043010480.013
positive regulation of immune system processGO:0002684900.013
cellular amino acid biosynthetic processGO:0008652320.013
nucleoside metabolic processGO:00091161790.013
negative regulation of multicellular organismal processGO:00512412030.013
negative regulation of cell developmentGO:0010721820.012
regulation of neuron deathGO:19012141150.012
camera type eye morphogenesisGO:004859320.012
negative regulation of neuron deathGO:1901215690.012
cellular modified amino acid metabolic processGO:0006575610.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
sensory organ developmentGO:0007423740.012
regulation of synaptic plasticityGO:0048167700.012
protein oligomerizationGO:00512591910.012
positive regulation of secretionGO:00510471400.012
positive regulation of cellular component movementGO:00512721020.012
regulation of cell cycleGO:0051726730.012
positive regulation of synaptic vesicle transportGO:190280530.012
cellular response to growth factor stimulusGO:00713631620.012
muscle tissue developmentGO:0060537580.012
positive regulation of gene expressionGO:00106282440.012
positive regulation of signalingGO:00230562700.012
female pregnancyGO:00075651220.012
macromolecule localizationGO:00330362520.012
phospholipid biosynthetic processGO:0008654290.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
positive regulation of cell developmentGO:00107201760.012
positive regulation of synaptic transmissionGO:0050806620.012
single organism behaviorGO:00447081300.012
positive regulation of ion transportGO:0043270940.012
positive regulation of cell communicationGO:00106472710.012
organic hydroxy compound transportGO:0015850770.012
negative regulation of cell communicationGO:00106481580.012
response to ethanolGO:00454711620.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
purine ribonucleoside metabolic processGO:00461281680.011
inorganic cation transmembrane transportGO:00986622020.011
ribonucleoside catabolic processGO:00424541260.011
transmission of nerve impulseGO:0019226420.011
intermediate filament based processGO:004510330.011
proteolysisGO:00065081750.011
axon developmentGO:0061564960.011
glycosyl compound catabolic processGO:19016581260.011
regulation of plasma lipoprotein particle levelsGO:009700630.011
neuron apoptotic processGO:0051402880.011
nucleobase containing compound catabolic processGO:00346551520.011
negative regulation of cell proliferationGO:00082851190.011
negative regulation of rna metabolic processGO:00512531230.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
nucleoside phosphate biosynthetic processGO:19012931020.011
cellular ion homeostasisGO:00068731840.011
forebrain developmentGO:0030900980.011
molting cycle processGO:002240420.011
calcium ion homeostasisGO:00550741620.011
positive regulation of protein modification processGO:00314011420.011
regulation of catabolic processGO:00098941130.011
multicellular organismal signalingGO:0035637440.011
action potentialGO:0001508540.011
cardiovascular system developmentGO:00723581340.011
response to mechanical stimulusGO:00096121340.011
development of primary sexual characteristicsGO:00451371070.010
regulation of calcium ion transportGO:0051924770.010
regulation of transferase activityGO:00513381230.010
glycosyl compound metabolic processGO:19016571820.010
peptide secretionGO:0002790860.010
ribonucleoside triphosphate metabolic processGO:00091991410.010
motor neuron axon guidanceGO:000804510.010
purine containing compound catabolic processGO:00725231380.010
vasculature developmentGO:0001944700.010
hair follicle developmentGO:000194220.010
response to glucoseGO:00097491360.010
nucleoside triphosphate metabolic processGO:00091411440.010
neuronal action potentialGO:0019228350.010
cytokine productionGO:0001816610.010
regulation of nucleotide metabolic processGO:00061401170.010
sequestering of calcium ionGO:005120880.010
purine ribonucleoside monophosphate metabolic processGO:0009167840.010
regulation of immune system processGO:00026821230.010
gonad developmentGO:00084061040.010
positive regulation of catalytic activityGO:00430851840.010
divalent metal ion transportGO:00708381320.010
positive regulation of neuron differentiationGO:00456661260.010
regulation of anatomical structure morphogenesisGO:00226031410.010

Sigmar1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
disease of metabolismDOID:001466700.014