Rattus norvegicus

0 known processes

Trem2

triggering receptor expressed on myeloid cells 2

Trem2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
anatomical structure morphogenesisGO:00096532980.096
regulation of rna metabolic processGO:00512523910.094
transcription dna templatedGO:00063513770.089
response to corticosteroidGO:00319602350.088
rna biosynthetic processGO:00327743800.086
cellular component movementGO:00069282480.083
regulation of nucleic acid templated transcriptionGO:19035063800.082
positive regulation of nitrogen compound metabolic processGO:00511733340.081
cellular response to endogenous stimulusGO:00714953770.078
cellular response to oxygen containing compoundGO:19017013860.076
regulation of multicellular organismal developmentGO:20000263760.075
response to peptide hormoneGO:00434342780.075
response to peptideGO:19016522920.074
response to acid chemicalGO:00011012220.073
rna metabolic processGO:00160704060.071
regulation of apoptotic processGO:00429813350.070
gland developmentGO:00487321550.068
cellular response to peptide hormone stimulusGO:00713751200.067
growthGO:00400071650.066
organophosphate metabolic processGO:00196373700.064
neuron projection developmentGO:00311752730.063
limb morphogenesisGO:003510840.063
positive regulation of nucleobase containing compound metabolic processGO:00459353190.063
regulation of rna biosynthetic processGO:20011413810.062
transcription from rna polymerase ii promoterGO:00063662520.062
positive regulation of response to stimulusGO:00485842850.061
cell morphogenesis involved in neuron differentiationGO:00486671060.060
cellular response to stressGO:00335542690.059
response to estrogenGO:00436272320.058
cellular response to peptideGO:19016531330.056
central nervous system developmentGO:00074173110.055
regulation of phosphorus metabolic processGO:00511743490.054
nucleic acid templated transcriptionGO:00976593790.054
organic acid metabolic processGO:00060822920.053
neuron developmentGO:00486662860.053
cell migrationGO:00164771970.053
neuron differentiationGO:00301823680.052
oxoacid metabolic processGO:00434362900.051
response to inorganic substanceGO:00100353770.051
response to oxidative stressGO:00069791860.051
cation homeostasisGO:00550801950.051
positive regulation of cell proliferationGO:00082842490.050
response to glucocorticoidGO:00513842230.048
cellular component morphogenesisGO:00329891550.048
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.048
response to extracellular stimulusGO:00099913800.048
regulation of cell differentiationGO:00455953200.047
cell projection organizationGO:00300303020.046
response to oxygen levelsGO:00704822650.046
locomotionGO:00400112370.045
cell cell signalingGO:00072673350.045
cellular response to nitrogen compoundGO:19016992100.044
positive regulation of gene expressionGO:00106282440.044
appendage morphogenesisGO:003510740.044
positive regulation of nucleic acid templated transcriptionGO:19035081970.044
regulation of transcription dna templatedGO:00063553740.043
positive regulation of molecular functionGO:00440932300.042
protein phosphorylationGO:00064683450.042
regulation of transcription from rna polymerase ii promoterGO:00063572340.042
localization of cellGO:00516742020.041
cellular chemical homeostasisGO:00550822470.041
positive regulation of rna metabolic processGO:00512542030.041
response to reactive oxygen speciesGO:00003021200.040
regulation of catalytic activityGO:00507903040.040
regulation of phosphate metabolic processGO:00192203490.040
developmental growthGO:00485891000.040
nucleoside catabolic processGO:00091641260.039
positive regulation of cellular biosynthetic processGO:00313282950.039
carboxylic acid metabolic processGO:00197522890.039
response to cytokineGO:00340972150.039
ion homeostasisGO:00508012120.038
biological adhesionGO:00226101100.038
monovalent inorganic cation transportGO:00156721720.038
ion transmembrane transportGO:00342203650.038
positive regulation of rna biosynthetic processGO:19026801970.038
cell motilityGO:00488702020.038
skeletal system developmentGO:0001501410.038
cell adhesionGO:00071551100.038
apoptotic processGO:00069153810.038
regulation of cell developmentGO:00602842630.037
response to ketoneGO:19016541820.037
response to estradiolGO:00323551640.037
transmembrane transportGO:00550854120.037
response to growth factorGO:00708481890.037
regulation of cell proliferationGO:00421273590.037
positive regulation of transcription dna templatedGO:00458931970.036
regulation of programmed cell deathGO:00430673410.036
regulation of cellular component organizationGO:00511283680.036
regulation of system processGO:00440572080.036
cell projection morphogenesisGO:00488581230.036
negative regulation of metabolic processGO:00098923310.036
ossificationGO:0001503700.036
carbohydrate derivative metabolic processGO:19011353460.035
regulation of molecular functionGO:00650093980.035
positive regulation of phosphate metabolic processGO:00459372620.035
response to woundingGO:00096112540.035
response to alkaloidGO:00432791320.035
multicellular organism reproductionGO:00325042330.035
cellular amino acid metabolic processGO:00065201070.035
positive regulation of developmental processGO:00510942830.035
brain developmentGO:00074202470.034
cellular cation homeostasisGO:00300031800.034
cellular response to lipidGO:00713962010.034
regulation of protein modification processGO:00313991940.034
intracellular signal transductionGO:00355563140.034
organonitrogen compound catabolic processGO:19015651790.034
regulation of nervous system developmentGO:00519602640.034
synaptic transmissionGO:00072682350.033
chemical homeostasisGO:00488782920.033
regulation of anatomical structure sizeGO:00900661350.033
cellular component biogenesisGO:00440853680.033
negative regulation of cell differentiationGO:0045596990.033
behaviorGO:00076102050.033
positive regulation of transportGO:00510502450.033
gliogenesisGO:0042063930.033
reproductive processGO:00224143720.033
tissue developmentGO:00098882520.033
cell growthGO:00160491040.033
negative regulation of gene expressionGO:00106291990.033
positive regulation of phosphorus metabolic processGO:00105622620.032
cellular divalent inorganic cation homeostasisGO:00725031620.032
cell morphogenesis involved in differentiationGO:00009041190.032
negative regulation of multicellular organismal processGO:00512412030.032
response to bacteriumGO:00096172000.032
regenerationGO:00310991630.032
ribose phosphate metabolic processGO:00196932350.032
cellular catabolic processGO:00442482950.032
head developmentGO:00603222470.032
cellular ketone metabolic processGO:0042180510.031
homeostatic processGO:00425923310.031
response to nutrient levelsGO:00316673700.031
blood circulationGO:00080151830.031
nucleoside metabolic processGO:00091161790.031
negative regulation of macromolecule metabolic processGO:00106052600.030
cellular response to organonitrogen compoundGO:00714171970.030
cellular calcium ion homeostasisGO:00068741600.030
amine metabolic processGO:0009308380.030
cytosolic calcium ion homeostasisGO:00514801400.030
positive regulation of protein metabolic processGO:00512471780.030
positive regulation of cell communicationGO:00106472710.030
positive regulation of signalingGO:00230562700.030
cation transportGO:00068123820.030
organ morphogenesisGO:0009887750.029
single organism catabolic processGO:00447122830.029
positive regulation of biosynthetic processGO:00098913190.029
axonogenesisGO:0007409710.029
axon developmentGO:0061564960.029
agingGO:00075682410.029
cellular homeostasisGO:00197252520.028
embryonic appendage morphogenesisGO:003511340.028
cell morphogenesisGO:00009021420.028
regulation of intracellular signal transductionGO:19025312180.028
cellular ion homeostasisGO:00068731840.028
cellular amine metabolic processGO:0044106380.028
endocytosisGO:0006897840.028
positive regulation of neuron differentiationGO:00456661260.027
purine nucleotide metabolic processGO:00061632290.027
ribonucleoside metabolic processGO:00091191740.027
response to mechanical stimulusGO:00096121340.027
circulatory system processGO:00030131830.027
forebrain developmentGO:0030900980.027
negative regulation of programmed cell deathGO:00430691830.027
liver developmentGO:0001889900.027
regulation of cellular ketone metabolic processGO:0010565270.027
organelle organizationGO:00069962660.027
cellular response to organic cyclic compoundGO:00714072020.027
calcium ion homeostasisGO:00550741620.027
cellular component assemblyGO:00226073600.027
cellular metal ion homeostasisGO:00068751720.027
positive regulation of nervous system developmentGO:00519621780.027
cellular response to growth factor stimulusGO:00713631620.027
glial cell differentiationGO:0010001650.027
neuron projection morphogenesisGO:00488121220.026
metal ion transportGO:00300012890.026
regulation of membrane potentialGO:00423911100.026
regulation of anatomical structure morphogenesisGO:00226031410.026
negative regulation of natural killer cell mediated immunityGO:000271640.026
regulation of cellular amino acid metabolic processGO:000652120.026
regulation of ion transportGO:00432692450.025
negative regulation of macromolecule biosynthetic processGO:00105581480.025
regulation of cellular amine metabolic processGO:003323880.025
carbohydrate derivative catabolic processGO:19011361470.025
divalent inorganic cation homeostasisGO:00725071650.025
mesoderm developmentGO:000749820.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.024
organic cyclic compound catabolic processGO:19013611750.024
purine ribonucleotide metabolic processGO:00091502270.024
response to external biotic stimulusGO:00432072210.024
reproductive system developmentGO:00614581280.024
positive regulation of cellular component organizationGO:00511302000.024
purine ribonucleoside triphosphate catabolic processGO:00092071220.024
regulation of cell migrationGO:00303341280.024
defense responseGO:00069521940.024
ribonucleotide metabolic processGO:00092592310.024
ras protein signal transductionGO:0007265290.024
negative regulation of developmental processGO:00510931250.023
receptor mediated endocytosisGO:0006898420.023
negative regulation of signalingGO:00230571570.023
regulation of signal transductionGO:00099663180.023
single organism cell adhesionGO:0098602460.023
wound healingGO:00420601220.023
catabolic processGO:00090563510.023
hepaticobiliary system developmentGO:0061008900.023
programmed cell deathGO:00125013920.023
vesicle mediated transportGO:00161921810.023
metal ion homeostasisGO:00550651860.023
response to other organismGO:00517072200.023
cell part morphogenesisGO:00329901230.023
purine ribonucleoside triphosphate metabolic processGO:00092051400.023
sensory perception of painGO:0019233730.023
reproductionGO:00000032450.023
tube developmentGO:0035295890.023
nucleotide metabolic processGO:00091172790.023
developmental process involved in reproductionGO:00030061590.022
embryonic limb morphogenesisGO:003032640.022
positive regulation of cell differentiationGO:00455972170.022
anterior posterior pattern specificationGO:000995210.022
reproductive structure developmentGO:00486081280.022
organophosphate catabolic processGO:00464341480.022
gastrulationGO:000736920.022
response to hydrogen peroxideGO:0042542890.022
regulation of synaptic transmissionGO:00508041410.022
glycosyl compound metabolic processGO:19016571820.022
development of primary sexual characteristicsGO:00451371070.022
nucleoside triphosphate catabolic processGO:00091431230.021
regulation of cellular protein metabolic processGO:00322682670.021
regulation of cell growthGO:0001558850.021
positive regulation of cell developmentGO:00107201760.021
positive regulation of catalytic activityGO:00430851840.021
circulatory system developmentGO:00723591340.021
positive regulation of apoptotic processGO:00430651540.021
regulation of cell projection organizationGO:00313441750.021
multi organism reproductive processGO:00447032620.021
cellular response to hormone stimulusGO:00328702470.021
glycosyl compound catabolic processGO:19016581260.021
purine nucleoside triphosphate catabolic processGO:00091461220.021
cellular response to external stimulusGO:00714961180.021
positive regulation of multicellular organismal processGO:00512403870.021
single organism carbohydrate metabolic processGO:00447231180.020
neurological system processGO:00508772190.020
purine ribonucleoside metabolic processGO:00461281680.020
negative regulation of apoptotic processGO:00430661810.020
negative regulation of cell deathGO:00605482290.020
regulation of neurogenesisGO:00507672470.020
purine containing compound metabolic processGO:00725212530.020
purine ribonucleoside catabolic processGO:00461301240.020
positive regulation of cellular amine metabolic processGO:003324030.020
negative regulation of rna biosynthetic processGO:19026791180.020
carbohydrate metabolic processGO:00059751300.020
response to molecule of bacterial originGO:00022371940.019
nucleoside triphosphate metabolic processGO:00091411440.019
nucleobase containing small molecule metabolic processGO:00550863160.019
positive regulation of phosphorylationGO:00423271770.019
regulation of neuron differentiationGO:00456642080.019
cellular response to fluid shear stressGO:007149840.019
negative regulation of transcription dna templatedGO:00458921160.019
negative regulation of cell communicationGO:00106481580.019
response to retinoic acidGO:0032526630.019
organic hydroxy compound metabolic processGO:19016151150.019
response to nutrientGO:00075842480.019
negative regulation of cellular metabolic processGO:00313242810.019
positive regulation of cytosolic calcium ion concentrationGO:00072041220.019
negative regulation of transportGO:00510511360.018
single organism biosynthetic processGO:00447113420.018
response to hyperoxiaGO:0055093450.018
regulation of growthGO:00400081050.018
nucleoside phosphate metabolic processGO:00067532830.018
immune system processGO:00023762040.018
nucleotide catabolic processGO:00091661390.018
regulation of immune system processGO:00026821230.018
cellular nitrogen compound catabolic processGO:00442701630.018
regulation of neuron projection developmentGO:00109751610.018
regulation of synaptic plasticityGO:0048167700.018
prostate gland epithelium morphogenesisGO:006074020.018
multi multicellular organism processGO:00447061380.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.018
cardiovascular system developmentGO:00723581340.018
positive regulation of cell deathGO:00109421840.018
organophosphate biosynthetic processGO:00904071430.018
inorganic cation transmembrane transportGO:00986622020.018
positive regulation of immune system processGO:0002684900.017
mapk cascadeGO:00001651400.017
purine nucleoside metabolic processGO:00422781690.017
response to increased oxygen levelsGO:0036296450.017
immune system developmentGO:0002520410.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
ribonucleoside triphosphate metabolic processGO:00091991410.017
nucleobase containing compound catabolic processGO:00346551520.017
protein complex assemblyGO:00064612630.017
single organism reproductive processGO:00447022970.017
ribonucleoside triphosphate catabolic processGO:00092031220.017
ribonucleoside catabolic processGO:00424541260.017
purine nucleoside triphosphate metabolic processGO:00091441410.017
immune responseGO:00069551040.017
muscle system processGO:00030121150.017
salivary gland morphogenesisGO:000743510.017
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.017
multicellular organismal signalingGO:0035637440.017
cellular response to extracellular stimulusGO:0031668730.017
female pregnancyGO:00075651220.017
purine nucleotide catabolic processGO:00061951360.017
positive regulation of purine nucleotide metabolic processGO:1900544910.017
anatomical structure formation involved in morphogenesisGO:0048646830.016
positive regulation of neuron projection developmentGO:0010976990.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
response to decreased oxygen levelsGO:00362932370.016
regulation of response to stressGO:00801341260.016
hematopoietic or lymphoid organ developmentGO:0048534360.016
regulation of cell adhesionGO:0030155520.016
protein complex subunit organizationGO:00718223020.016
rhythmic processGO:00485111560.016
organic substance catabolic processGO:19015753160.016
heart morphogenesisGO:000300730.016
response to organophosphorusGO:00466831020.016
sexual reproductionGO:00199531480.016
action potentialGO:0001508540.016
negative regulation of molecular functionGO:00440921330.016
response to vitaminGO:00332731310.016
multicellular organismal reproductive processGO:00486092330.016
macromolecular complex subunit organizationGO:00439333390.015
purine nucleoside catabolic processGO:00061521240.015
positive regulation of neurogenesisGO:00507691650.015
digestive system developmentGO:0055123410.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
nucleoside phosphate catabolic processGO:19012921400.015
small gtpase mediated signal transductionGO:0007264360.015
protein complex biogenesisGO:00702712630.015
positive regulation of signal transductionGO:00099671750.015
heart developmentGO:0007507720.015
regulation of cellular component movementGO:00512701500.015
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.015
response to purine containing compoundGO:00140741260.015
response to hypoxiaGO:00016662310.015
transmission of nerve impulseGO:0019226420.015
organic acid transportGO:00158491160.015
cellular lipid metabolic processGO:00442552080.015
regulation of kinase activityGO:00435491170.015
negative regulation of biosynthetic processGO:00098901680.015
potassium ion transportGO:0006813970.015
negative regulation of cellular protein metabolic processGO:00322691060.015
regulation of cell motilityGO:20001451310.015
regulation of protein phosphorylationGO:00019321830.015
formation of primary germ layerGO:000170410.015
blood vessel morphogenesisGO:0048514580.015
response to ethanolGO:00454711620.015
regulation of cell morphogenesis involved in differentiationGO:0010769720.014
hemopoiesisGO:0030097340.014
positive regulation of intracellular signal transductionGO:19025331380.014
positive regulation of programmed cell deathGO:00430681570.014
negative regulation of cellular biosynthetic processGO:00313271610.014
somatic stem cell divisionGO:004810320.014
palate developmentGO:006002120.014
cellular response to insulin stimulusGO:0032869810.014
angiogenesisGO:0001525530.014
purine ribonucleotide catabolic processGO:00091541360.014
urogenital system developmentGO:0001655780.014
purine containing compound catabolic processGO:00725231380.014
positive regulation of protein modification processGO:00314011420.014
inflammatory responseGO:00069541500.014
heterocycle catabolic processGO:00467001670.014
regulation of smooth muscle contractionGO:0006940290.014
establishment of protein localizationGO:00451841410.014
wnt signaling pathway planar cell polarity pathwayGO:006007120.014
response to lipopolysaccharideGO:00324961910.014
divalent metal ion transportGO:00708381320.014
regulation of cellular catabolic processGO:00313291010.014
single organismal cell cell adhesionGO:0016337420.014
regulation of cell morphogenesisGO:0022604770.014
negative regulation of nervous system developmentGO:0051961790.014
regulation of locomotionGO:00400121480.014
regulation of hydrolase activityGO:00513361430.014
cellular carbohydrate metabolic processGO:0044262720.013
organ formationGO:004864530.013
secretionGO:00469033070.013
muscle structure developmentGO:0061061870.013
protein oligomerizationGO:00512591910.013
platelet aggregationGO:007052740.013
positive regulation of cellular catabolic processGO:0031331710.013
response to interleukin 1GO:0070555550.013
positive regulation of ion transportGO:0043270940.013
gamete generationGO:00072761240.013
calcium ion transportGO:00068161310.013
small molecule biosynthetic processGO:00442831240.013
cation transmembrane transportGO:00986552630.013
membrane organizationGO:0061024940.013
aromatic compound catabolic processGO:00194391680.013
response to testosteroneGO:0033574550.013
regulation of hormone levelsGO:00108171870.013
macromolecular complex assemblyGO:00650032730.013
regulation of blood pressureGO:0008217830.012
regulation of canonical wnt signaling pathwayGO:006082840.012
blood vessel developmentGO:0001568690.012
telencephalon developmentGO:0021537620.012
protein autophosphorylationGO:0046777660.012
response to carbohydrateGO:00097431830.012
salivary gland developmentGO:000743130.012
vasculature developmentGO:0001944700.012
oxidation reduction processGO:00551143040.012
motor neuron axon guidanceGO:000804510.012
positive regulation of hydrolase activityGO:0051345860.012
regulation of homeostatic processGO:00328441010.012
protein localizationGO:00081041910.012
multicellular organism growthGO:003526410.012
cellular response to acid chemicalGO:0071229750.012
response to biotic stimulusGO:00096072260.012
muscle contractionGO:0006936880.012
negative regulation of rna metabolic processGO:00512531230.012
regulation of cellular localizationGO:00603412630.012
positive regulation of nucleotide metabolic processGO:0045981910.012
negative regulation of response to stimulusGO:00485851550.012
cellular response to cytokine stimulusGO:00713451270.012
regulation of smooth muscle cell migrationGO:0014910360.012
organ regenerationGO:00311001010.012
neuron apoptotic processGO:0051402880.012
positive regulation of smooth muscle cell proliferationGO:0048661510.012
neuronal action potentialGO:0019228350.012
b cell differentiationGO:003018320.012
regulation of purine nucleotide metabolic processGO:19005421150.012
neuromuscular processGO:005090520.012
response to monosaccharideGO:00342841590.012
cytoskeleton organizationGO:00070101110.012
rho protein signal transductionGO:0007266110.012
morphogenesis of a polarized epitheliumGO:000173810.012
negative regulation of neurogenesisGO:0050768780.012
cellular macromolecule localizationGO:00707271220.012
organonitrogen compound biosynthetic processGO:19015661670.012
sensory perceptionGO:00076001010.012
response to insulinGO:00328681330.012
positive regulation of purine nucleotide catabolic processGO:0033123530.012
response to metal ionGO:00100382530.012
signal transduction by phosphorylationGO:00230141440.012
negative regulation of signal transductionGO:0009968830.012
tissue regenerationGO:0042246360.011
glycerolipid metabolic processGO:0046486670.011
single organism intracellular transportGO:19025821660.011
establishment of tissue polarityGO:000716420.011
negative regulation of innate immune responseGO:004582440.011
cell type specific apoptotic processGO:00972851340.011
regulation of vesicle mediated transportGO:0060627810.011
positive regulation of protein phosphorylationGO:00019341350.011
smooth muscle cell proliferationGO:0048659770.011
stem cell divisionGO:001714540.011
regulation of body fluid levelsGO:0050878900.011
negative regulation of canonical wnt signaling pathwayGO:009009040.011
developmental growth involved in morphogenesisGO:0060560330.011
nitrogen compound transportGO:00717052290.011
embryonic hindlimb morphogenesisGO:003511620.011
positive regulation of catabolic processGO:0009896780.011
regulation of purine nucleotide catabolic processGO:0033121650.011
response to fatty acidGO:0070542650.011
sequestering of calcium ionGO:005120880.011
single organism organelle organizationGO:19025891800.011
ribonucleoside monophosphate metabolic processGO:0009161880.011
negative regulation of phosphate metabolic processGO:0045936800.011
positive regulation of cellular protein metabolic processGO:00322701670.011
atp catabolic processGO:0006200540.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
negative regulation of mitotic cell cycle phase transitionGO:190199130.011
anion transportGO:00068201780.011
cellular response to mechanical stimulusGO:0071260480.011
response to activityGO:0014823730.011
response to transition metal nanoparticleGO:19902671220.011
hematopoietic progenitor cell differentiationGO:000224420.011
cell cycleGO:00070491010.011
peptidyl tyrosine modificationGO:0018212720.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.011
regulation of nucleotide metabolic processGO:00061401170.011
muscle cell proliferationGO:0033002840.011
negative regulation of cell cycle phase transitionGO:190198840.011
response to toxic substanceGO:00096361330.011
carboxylic acid transportGO:00469421150.010
regulation of blood circulationGO:19035221100.010
regulation of neuron apoptotic processGO:0043523830.010
negative regulation of cell developmentGO:0010721820.010
regulation of protein metabolic processGO:00512462890.010
regulation of calcium ion transportGO:0051924770.010
hexose metabolic processGO:0019318580.010
positive regulation of myeloid leukocyte differentiationGO:000276370.010
regulation of catabolic processGO:00098941130.010
cellular response to reactive oxygen speciesGO:0034614550.010
chemotaxisGO:0006935660.010
regulation of metal ion transportGO:00109591180.010

Trem2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
musculoskeletal system diseaseDOID:1700.017
connective tissue diseaseDOID:6500.014
immune system diseaseDOID:291400.010